#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P06725 uniprotkb:Q16666-2 intact:EBI-9545359|uniprotkb:Q7M6K8 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 psi-mi:pp65_hcmva(display_long)|uniprotkb:UL83(gene name)|psi-mi:UL83(display_short)|uniprotkb:65 kDa matrix phosphoprotein(gene name synonym)|uniprotkb:Phosphoprotein UL83(gene name synonym)|uniprotkb:Tegument protein UL83(gene name synonym) psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Li et al. (2013) pubmed:24237704|imex:IM-22950 taxid:10360(hcmva)|taxid:10360("Human cytomegalovirus (strain AD169) (HHV-5)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9545375|imex:IM-22950-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-198933|dip:DIP-61111N|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0042025"(host cell nucleus)|interpro:IPR008649(Betaherpesvirus UL8283, N-terminal)|interpro:IPR036157|rcsb pdb:2X4R|rcsb pdb:2X4T|rcsb pdb:3GSO intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) - - isoform-comment:Major isoform. figure legend:2C and D and 3C|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/06/05 2014/10/16 rogid:E08MkuldmXJHq/yUezvPsoyd4eo10360 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 intact-crc:E5B60A3120CB19B5|rigid:JVE5EZgTyzRoLjsZRYFpDqQApgI false flag tag:c-c|necessary binding region:1-395..395 green fluorescent protein tag:c-c|necessary binding region:1-160 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P41218 uniprotkb:P06725 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-9545359|uniprotkb:Q7M6K8 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:pp65_hcmva(display_long)|uniprotkb:UL83(gene name)|psi-mi:UL83(display_short)|uniprotkb:65 kDa matrix phosphoprotein(gene name synonym)|uniprotkb:Phosphoprotein UL83(gene name synonym)|uniprotkb:Tegument protein UL83(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Li et al. (2013) pubmed:24237704|imex:IM-22950 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10360(hcmva)|taxid:10360("Human cytomegalovirus (strain AD169) (HHV-5)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9545422|imex:IM-22950-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG reactome:R-HSA-198933|dip:DIP-61111N|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0042025"(host cell nucleus)|interpro:IPR008649(Betaherpesvirus UL8283, N-terminal)|interpro:IPR036157|rcsb pdb:2X4R|rcsb pdb:2X4T|rcsb pdb:3GSO - - - figure legend:2D|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/06/05 2014/10/16 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:E08MkuldmXJHq/yUezvPsoyd4eo10360 intact-crc:53D18D7EA53B59D7|rigid:oMqWfG05wKLIRJEJYJErrBJ+AfM false sufficient binding region:1-160|green fluorescent protein tag:c-c flag tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q6K0P9 uniprotkb:P06725 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-9545359|uniprotkb:Q7M6K8 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:pp65_hcmva(display_long)|uniprotkb:UL83(gene name)|psi-mi:UL83(display_short)|uniprotkb:65 kDa matrix phosphoprotein(gene name synonym)|uniprotkb:Phosphoprotein UL83(gene name synonym)|uniprotkb:Tegument protein UL83(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Li et al. (2013) pubmed:24237704|imex:IM-22950 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10360(hcmva)|taxid:10360("Human cytomegalovirus (strain AD169) (HHV-5)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9545385|imex:IM-22950-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 reactome:R-HSA-198933|dip:DIP-61111N|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0042025"(host cell nucleus)|interpro:IPR008649(Betaherpesvirus UL8283, N-terminal)|interpro:IPR036157|rcsb pdb:2X4R|rcsb pdb:2X4T|rcsb pdb:3GSO - - - figure legend:2D|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/06/05 2014/10/16 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:E08MkuldmXJHq/yUezvPsoyd4eo10360 intact-crc:FC498B7704032B39|rigid:HpV3SztrbAtn7owLy2cVROcCtTo false green fluorescent protein tag:c-c|sufficient binding region:1-160 flag tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9ULZ3 uniprotkb:O14862 intact:EBI-751215|uniprotkb:Q96D12|uniprotkb:Q9BSZ5|uniprotkb:Q9HBD0|uniprotkb:Q9NXJ8|ensembl:ENSP00000247470 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 psi-mi:asc_human(display_long)|uniprotkb:PYD and CARD domain-containing protein(gene name synonym)|uniprotkb:Target of methylation-induced silencing 1(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 5(gene name synonym)|uniprotkb:ASC(gene name synonym)|uniprotkb:CARD5(gene name synonym)|uniprotkb:TMS1(gene name synonym)|uniprotkb:PYCARD(gene name)|psi-mi:PYCARD(display_short) psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Li et al. (2013) pubmed:24237704|imex:IM-22950 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9545458|imex:IM-22950-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_037390.2|refseq:NP_660183.1|dip:DIP-27618N|ensembl:ENSG00000103490(gene)|ensembl:ENST00000247470(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001773"(myeloid dendritic cell activation)|go:"GO:0002020"(protease binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0002277"(myeloid dendritic cell activation involved in immune response)|go:"GO:0002588"(positive regulation of antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0002821"(positive regulation of adaptive immune response)|go:"GO:0005138"(interleukin-6 receptor binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010803"(regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0017024"(myosin I binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032090"(Pyrin domain binding)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044351"(macropinocytosis)|go:"GO:0045087"(innate immune response)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070700"(BMP receptor binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0072558"(NLRP1 inflammasome complex)|go:"GO:0072559"(NLRP3 inflammasome complex)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097153"(cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:2000406"(positive regulation of T cell migration)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001242"(regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR004020(Pyrin)|interpro:IPR011029(DEATH-like)|interpro:IPR033516|rcsb pdb:1UCP|rcsb pdb:2KN6|rcsb pdb:3J63|rcsb pdb:5H8O|rcsb pdb:6K99|rcsb pdb:6KI0|rcsb pdb:6N1H|rcsb pdb:7KEU|reactome:R-HSA-5660668|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-844615|reactome:R-HSA-9660826 rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N - - - figure legend:Supplement. S2B|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/06/05 2014/10/16 rogid:FfpNhWZB7QfBFjoYBFZwTNpxntw9606 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 intact-crc:2CF1F9A55758A935|rigid:stiVjdxm1ieH106ep50DBvYwOnk false ha tag:c-c green fluorescent protein tag:c-c|sufficient binding region:1-93 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q16666-2 uniprotkb:Q16666-2 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Li et al. (2013) pubmed:24237704|imex:IM-22950 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9545514|imex:IM-22950-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) - isoform-comment:Major isoform. isoform-comment:Major isoform. figure legend:2H|comment:IFI16 oligomers have been detected. Oigimerization was inhibited by presence of HCMV UL83.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-fibroblast)|taxid:9606("Homo sapiens normal diploid fibroblasts (HDF0") - 2014/06/05 2014/10/16 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 intact-crc:3C40186F6DB85122|rigid:oCViYXQa8RUMNonzZW7sKLUIdi0 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q16666-2 uniprotkb:Q16666-2 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Li et al. (2013) pubmed:24237704|imex:IM-22950 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9545479|imex:IM-22950-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) - isoform-comment:Major isoform. isoform-comment:Major isoform. figure legend:2H|comment:IFI16 oligomers have been detected. Oigimerization was inhibited by presence of HCMV UL83.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/06/05 2014/10/16 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 intact-crc:9D2DBA5D2C3D287C|rigid:oCViYXQa8RUMNonzZW7sKLUIdi0 false sufficient binding region:1-160|green fluorescent protein tag:c-c sufficient binding region:1-160|green fluorescent protein tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)