#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O35245	uniprotkb:E2JF22	intact:EBI-9823400|uniprotkb:C0KJK2|uniprotkb:E9Q4F6|uniprotkb:E9QQA3|uniprotkb:Q8BPR6|uniprotkb:Q9ES37|uniprotkb:Q9QWP0|uniprotkb:Q9Z193|uniprotkb:Q9Z194|ensembl:ENSMUSP00000084041	intact:EBI-9837938	psi-mi:pkd2_mouse(display_long)|uniprotkb:Pkd2(gene name)|psi-mi:Pkd2(display_short)|uniprotkb:Polycystic kidney disease 2 protein homolog(gene name synonym)|uniprotkb:TRPP2(gene name synonym)|uniprotkb:Transient receptor potential cation channel subfamily P member 2(gene name synonym)	psi-mi:piez1_mouse(display_long)|uniprotkb:Piezo1(gene name)|psi-mi:Piezo1(display_short)|uniprotkb:Fam38a(gene name synonym)|uniprotkb:Protein FAM38A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Peyronnet et al. (2013)	pubmed:24157948|imex:IM-23195	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9837999|imex:IM-23195-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032887.3|refseq:XP_006534878.1|dip:DIP-60904N|ensembl:ENSMUSG00000034462(gene)|ensembl:ENSMUST00000086831(transcript)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0001947"(heart looping)|go:"GO:0002133"(polycystin complex)|go:"GO:0003127"(detection of nodal flow)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015267"(channel activity)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0021510"(spinal cord development)|go:"GO:0021915"(neural tube development)|go:"GO:0022843"(voltage-gated cation channel activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031514"(motile cilium)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0034703"(cation channel complex)|go:"GO:0035502"(metanephric part of ureteric bud development)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0035904"(aorta development)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042805"(actinin binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044782"(cilium organization)|go:"GO:0045180"(basal cortex)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051117"(ATPase binding)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060674"(placenta blood vessel development)|go:"GO:0061333"(renal tubule morphogenesis)|go:"GO:0061441"(renal artery morphogenesis)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071458"(integral component of cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:0071464"(cellular response to hydrostatic pressure)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071910"(determination of liver left/right asymmetry)|go:"GO:0072075"(metanephric mesenchyme development)|go:"GO:0072177"(mesonephric duct development)|go:"GO:0072208"(metanephric smooth muscle tissue development)|go:"GO:0072214"(metanephric cortex development)|go:"GO:0072218"(metanephric ascending thin limb development)|go:"GO:0072219"(metanephric cortical collecting duct development)|go:"GO:0072235"(metanephric distal tubule development)|go:"GO:0072284"(metanephric S-shaped body morphogenesis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0097730"(non-motile cilium)|go:"GO:0098662"(inorganic cation transmembrane transport)|go:"GO:0198738"(cell-cell signaling by wnt)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:0005262"(calcium channel activity)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003915(Polycystic kidney disease type 2 protein)|interpro:IPR011992(EF-Hand type)|interpro:IPR013122(Polycystin cation channel, PKD1/PKD2)|interpro:IPR027359|reactome:R-MMU-5620916	dip:DIP-59655N|go:"GO:0005261"(cation channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006812"(cation transport)|go:"GO:0008381"(mechanosensitive ion channel activity)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033625"(positive regulation of integrin activation)|go:"GO:0033634"(positive regulation of cell-cell adhesion mediated by integrin)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0071260"(cellular response to mechanical stimulus)|interpro:IPR027272|interpro:IPR031334|interpro:IPR031805|rcsb pdb:3JAC|rcsb pdb:4RAX|rcsb pdb:5Z10|rcsb pdb:6B3R|rcsb pdb:6BPZ|rcsb pdb:6LQI	-	-	-	figure legend:sf8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2014/10/09	2014/10/16	rogid:LeuBtL/A49zoh206XX45E1g8n/810090	rogid:hdah8UO1NXUhBKy6tqyZOD22z+E10090	intact-crc:5100CF7F13A3AC77|rigid:SytOJok3/9mf10MI1AkZAwNXCFs	false	myc tag:?-?|binding-associated region:1-740	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O35245	uniprotkb:E2JF22	intact:EBI-9823400|uniprotkb:C0KJK2|uniprotkb:E9Q4F6|uniprotkb:E9QQA3|uniprotkb:Q8BPR6|uniprotkb:Q9ES37|uniprotkb:Q9QWP0|uniprotkb:Q9Z193|uniprotkb:Q9Z194|ensembl:ENSMUSP00000084041	intact:EBI-9837938	psi-mi:pkd2_mouse(display_long)|uniprotkb:Pkd2(gene name)|psi-mi:Pkd2(display_short)|uniprotkb:Polycystic kidney disease 2 protein homolog(gene name synonym)|uniprotkb:TRPP2(gene name synonym)|uniprotkb:Transient receptor potential cation channel subfamily P member 2(gene name synonym)	psi-mi:piez1_mouse(display_long)|uniprotkb:Piezo1(gene name)|psi-mi:Piezo1(display_short)|uniprotkb:Fam38a(gene name synonym)|uniprotkb:Protein FAM38A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Peyronnet et al. (2013)	pubmed:24157948|imex:IM-23195	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9837936|imex:IM-23195-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032887.3|refseq:XP_006534878.1|dip:DIP-60904N|ensembl:ENSMUSG00000034462(gene)|ensembl:ENSMUST00000086831(transcript)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0001947"(heart looping)|go:"GO:0002133"(polycystin complex)|go:"GO:0003127"(detection of nodal flow)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015267"(channel activity)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0021510"(spinal cord development)|go:"GO:0021915"(neural tube development)|go:"GO:0022843"(voltage-gated cation channel activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031514"(motile cilium)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0034703"(cation channel complex)|go:"GO:0035502"(metanephric part of ureteric bud development)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0035904"(aorta development)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042805"(actinin binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044782"(cilium organization)|go:"GO:0045180"(basal cortex)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051117"(ATPase binding)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060674"(placenta blood vessel development)|go:"GO:0061333"(renal tubule morphogenesis)|go:"GO:0061441"(renal artery morphogenesis)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071458"(integral component of cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:0071464"(cellular response to hydrostatic pressure)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071910"(determination of liver left/right asymmetry)|go:"GO:0072075"(metanephric mesenchyme development)|go:"GO:0072177"(mesonephric duct development)|go:"GO:0072208"(metanephric smooth muscle tissue development)|go:"GO:0072214"(metanephric cortex development)|go:"GO:0072218"(metanephric ascending thin limb development)|go:"GO:0072219"(metanephric cortical collecting duct development)|go:"GO:0072235"(metanephric distal tubule development)|go:"GO:0072284"(metanephric S-shaped body morphogenesis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0097730"(non-motile cilium)|go:"GO:0098662"(inorganic cation transmembrane transport)|go:"GO:0198738"(cell-cell signaling by wnt)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:0005262"(calcium channel activity)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003915(Polycystic kidney disease type 2 protein)|interpro:IPR011992(EF-Hand type)|interpro:IPR013122(Polycystin cation channel, PKD1/PKD2)|interpro:IPR027359|reactome:R-MMU-5620916	dip:DIP-59655N|go:"GO:0005261"(cation channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006812"(cation transport)|go:"GO:0008381"(mechanosensitive ion channel activity)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033625"(positive regulation of integrin activation)|go:"GO:0033634"(positive regulation of cell-cell adhesion mediated by integrin)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0071260"(cellular response to mechanical stimulus)|interpro:IPR027272|interpro:IPR031334|interpro:IPR031805|rcsb pdb:3JAC|rcsb pdb:4RAX|rcsb pdb:5Z10|rcsb pdb:6B3R|rcsb pdb:6BPZ|rcsb pdb:6LQI	-	-	-	figure legend:f5a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2014/10/09	2014/10/16	rogid:LeuBtL/A49zoh206XX45E1g8n/810090	rogid:hdah8UO1NXUhBKy6tqyZOD22z+E10090	intact-crc:72EF875AD5280A2A|rigid:SytOJok3/9mf10MI1AkZAwNXCFs	false	binding-associated region:1-203|myc tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O35245	uniprotkb:E2JF22	intact:EBI-9823400|uniprotkb:C0KJK2|uniprotkb:E9Q4F6|uniprotkb:E9QQA3|uniprotkb:Q8BPR6|uniprotkb:Q9ES37|uniprotkb:Q9QWP0|uniprotkb:Q9Z193|uniprotkb:Q9Z194|ensembl:ENSMUSP00000084041	intact:EBI-9837938	psi-mi:pkd2_mouse(display_long)|uniprotkb:Pkd2(gene name)|psi-mi:Pkd2(display_short)|uniprotkb:Polycystic kidney disease 2 protein homolog(gene name synonym)|uniprotkb:TRPP2(gene name synonym)|uniprotkb:Transient receptor potential cation channel subfamily P member 2(gene name synonym)	psi-mi:piez1_mouse(display_long)|uniprotkb:Piezo1(gene name)|psi-mi:Piezo1(display_short)|uniprotkb:Fam38a(gene name synonym)|uniprotkb:Protein FAM38A(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Peyronnet et al. (2013)	pubmed:24157948|imex:IM-23195	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-9844041|imex:IM-23195-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032887.3|refseq:XP_006534878.1|dip:DIP-60904N|ensembl:ENSMUSG00000034462(gene)|ensembl:ENSMUST00000086831(transcript)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0001947"(heart looping)|go:"GO:0002133"(polycystin complex)|go:"GO:0003127"(detection of nodal flow)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015267"(channel activity)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0021510"(spinal cord development)|go:"GO:0021915"(neural tube development)|go:"GO:0022843"(voltage-gated cation channel activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031514"(motile cilium)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0034703"(cation channel complex)|go:"GO:0035502"(metanephric part of ureteric bud development)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0035904"(aorta development)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042805"(actinin binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044782"(cilium organization)|go:"GO:0045180"(basal cortex)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051117"(ATPase binding)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060674"(placenta blood vessel development)|go:"GO:0061333"(renal tubule morphogenesis)|go:"GO:0061441"(renal artery morphogenesis)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071458"(integral component of cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:0071464"(cellular response to hydrostatic pressure)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071910"(determination of liver left/right asymmetry)|go:"GO:0072075"(metanephric mesenchyme development)|go:"GO:0072177"(mesonephric duct development)|go:"GO:0072208"(metanephric smooth muscle tissue development)|go:"GO:0072214"(metanephric cortex development)|go:"GO:0072218"(metanephric ascending thin limb development)|go:"GO:0072219"(metanephric cortical collecting duct development)|go:"GO:0072235"(metanephric distal tubule development)|go:"GO:0072284"(metanephric S-shaped body morphogenesis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0097730"(non-motile cilium)|go:"GO:0098662"(inorganic cation transmembrane transport)|go:"GO:0198738"(cell-cell signaling by wnt)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:0005262"(calcium channel activity)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003915(Polycystic kidney disease type 2 protein)|interpro:IPR011992(EF-Hand type)|interpro:IPR013122(Polycystin cation channel, PKD1/PKD2)|interpro:IPR027359|reactome:R-MMU-5620916	dip:DIP-59655N|go:"GO:0005261"(cation channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006812"(cation transport)|go:"GO:0008381"(mechanosensitive ion channel activity)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033625"(positive regulation of integrin activation)|go:"GO:0033634"(positive regulation of cell-cell adhesion mediated by integrin)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0071260"(cellular response to mechanical stimulus)|interpro:IPR027272|interpro:IPR031334|interpro:IPR031805|rcsb pdb:3JAC|rcsb pdb:4RAX|rcsb pdb:5Z10|rcsb pdb:6B3R|rcsb pdb:6BPZ|rcsb pdb:6LQI	go:"GO:0005886"(plasma membrane)	-	-	figure legend:sf9|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-prox_tubule_cell)|taxid:10090(Mouse proximal tubule cells)	-	2014/10/09	2014/10/16	rogid:LeuBtL/A49zoh206XX45E1g8n/810090	rogid:hdah8UO1NXUhBKy6tqyZOD22z+E10090	intact-crc:C3A72091186B2F7A|rigid:SytOJok3/9mf10MI1AkZAwNXCFs	false	binding-associated region:1-740|mcherry fluorescent protein tag:?-?	enhanced green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)