#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O43502	uniprotkb:Q86YC2	intact:EBI-2267048|uniprotkb:Q3B783|uniprotkb:O43503|intact:EBI-28969664|ensembl:ENSP00000336701	intact:EBI-1222653|uniprotkb:Q8N7Y6|uniprotkb:Q8ND31|uniprotkb:Q9H6W1|uniprotkb:A6NIE1|ensembl:ENSP00000261584	psi-mi:ra51c_human(display_long)|uniprotkb:RAD51 homolog C(gene name synonym)|uniprotkb:RAD51C(gene name)|psi-mi:RAD51C(display_short)|uniprotkb:RAD51L2(gene name synonym)|uniprotkb:RAD51-like protein 2(gene name synonym)	psi-mi:palb2_human(display_long)|uniprotkb:PALB2(gene name)|psi-mi:PALB2(display_short)|uniprotkb:FANCN(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Park et al. (2013)	imex:IM-22188|pubmed:24141787	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9118380|imex:IM-22188-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000336701|ensembl:ENST00000421782|ensembl:ENSP00000391450|refseq:NP_002867.1|refseq:NP_478123.1|dip:DIP-41247N|ensembl:ENSG00000108384(gene)|ensembl:ENST00000337432(transcript)|go:"GO:0000707"(meiotic DNA recombinase assembly)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007066"(female meiosis sister chromatid cohesion)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030054"(cell junction)|go:"GO:0033063"(Rad51B-Rad51C-Rad51D-XRCC2 complex)|go:"GO:0033065"(Rad51C-XRCC3 complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|mint:O43502|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|reactome:R-HSA-983231	refseq:NP_078951.2|dip:DIP-38427N|ensembl:ENSG00000083093(gene)|ensembl:ENST00000261584(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001756"(somitogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007498"(mesoderm development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0048568"(embryonic organ development)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031920|interpro:IPR036322|interpro:IPR042417|mint:Q86YC2|rcsb pdb:2W18|rcsb pdb:3EU7|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|go:"GO:0001833"(inner cell mass cell proliferation)	-	-	-	figure legend:1B|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2014/02/06	2015/12/03	rogid:z3aviP3W7VXZGS7njC09B9M+fZs9606	rogid:/CusSIimN2s+1JZ83gI0GtaHdz09606	intact-crc:A6AAB966F29AC716|rigid:19NtrhBEdVRX6VYRuZNNpdKQByk	false	flag tag:n-n|his tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O43502	uniprotkb:P51587	intact:EBI-2267048|uniprotkb:Q3B783|uniprotkb:O43503|intact:EBI-28969664|ensembl:ENSP00000336701	intact:EBI-79792|ensembl:ENSP00000369497|ensembl:ENSP00000439902|uniprotkb:Q5TBJ7|uniprotkb:O00183|uniprotkb:O15008|uniprotkb:Q13879	psi-mi:ra51c_human(display_long)|uniprotkb:RAD51 homolog C(gene name synonym)|uniprotkb:RAD51C(gene name)|psi-mi:RAD51C(display_short)|uniprotkb:RAD51L2(gene name synonym)|uniprotkb:RAD51-like protein 2(gene name synonym)	psi-mi:brca2_human(display_long)|uniprotkb:BRCA2(gene name)|psi-mi:BRCA2(display_short)|uniprotkb:FANCD1(gene name synonym)|uniprotkb:FACD(gene name synonym)|uniprotkb:Fanconi anemia group D1 protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Park et al. (2013)	imex:IM-22188|pubmed:24141787	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9118380|imex:IM-22188-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000336701|ensembl:ENST00000421782|ensembl:ENSP00000391450|refseq:NP_002867.1|refseq:NP_478123.1|dip:DIP-41247N|ensembl:ENSG00000108384(gene)|ensembl:ENST00000337432(transcript)|go:"GO:0000707"(meiotic DNA recombinase assembly)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007066"(female meiosis sister chromatid cohesion)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030054"(cell junction)|go:"GO:0033063"(Rad51B-Rad51C-Rad51D-XRCC2 complex)|go:"GO:0033065"(Rad51C-XRCC3 complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|mint:O43502|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|reactome:R-HSA-983231	ensembl:ENSG00000139618(gene)|ensembl:ENST00000380152(transcript)|ensembl:ENST00000544455(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007569"(cell aging)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008585"(female gonad development)|go:"GO:0010165"(response to X-ray)|go:"GO:0010225"(response to UV-C)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030141"(secretory granule)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033593"(BRCA2-MAGE-D1 complex)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048478"(replication fork protection)|go:"GO:0051298"(centrosome duplication)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:1990426"(mitotic recombination-dependent replication fork processing)|interpro:IPR002093(BRCA2 repeat)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR015187(BRCA2, oligonucleotide/oligosaccharide-binding 1)|interpro:IPR015188(BRCA2, oligonucleotide/oligosaccharide-binding 3)|interpro:IPR015205(Tower)|interpro:IPR015252(BRCA2, helical)|interpro:IPR015525(Breast cancer type 2 susceptibility protein)|interpro:IPR036315|mint:P51587|rcsb pdb:1N0W|rcsb pdb:3EU7|rcsb pdb:6GY2|go:"GO:0007141"(male meiosis I)|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|rcsb pdb:6HQU|refseq:NP_000050.2|dip:DIP-24214N	-	-	-	figure legend:1B|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2014/02/06	2015/12/03	rogid:z3aviP3W7VXZGS7njC09B9M+fZs9606	rogid:GvNlXMFXTHiRgOGT5EBlQUVh/+k9606	intact-crc:A6AAB966F29AC716|rigid:19NtrhBEdVRX6VYRuZNNpdKQByk	false	flag tag:n-n|his tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O43502	uniprotkb:Q06609	intact:EBI-2267048|uniprotkb:Q3B783|uniprotkb:O43503|intact:EBI-28969664|ensembl:ENSP00000336701	intact:EBI-297202|uniprotkb:Q6FHX9|ensembl:ENSP00000267868|ensembl:ENSP00000433924|uniprotkb:B0FXP0|uniprotkb:Q9BV60|intact:EBI-1059207|uniprotkb:B2R8T6|uniprotkb:Q6ZNA8	psi-mi:ra51c_human(display_long)|uniprotkb:RAD51 homolog C(gene name synonym)|uniprotkb:RAD51C(gene name)|psi-mi:RAD51C(display_short)|uniprotkb:RAD51L2(gene name synonym)|uniprotkb:RAD51-like protein 2(gene name synonym)	psi-mi:rad51_human(display_long)|uniprotkb:RAD51(gene name)|psi-mi:RAD51(display_short)|uniprotkb:RAD51A(gene name synonym)|uniprotkb:RECA(gene name synonym)|uniprotkb:RAD51 homolog A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Park et al. (2013)	imex:IM-22188|pubmed:24141787	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9119758|imex:IM-22188-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000336701|ensembl:ENST00000421782|ensembl:ENSP00000391450|refseq:NP_002867.1|refseq:NP_478123.1|dip:DIP-41247N|ensembl:ENSG00000108384(gene)|ensembl:ENST00000337432(transcript)|go:"GO:0000707"(meiotic DNA recombinase assembly)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007066"(female meiosis sister chromatid cohesion)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030054"(cell junction)|go:"GO:0033063"(Rad51B-Rad51C-Rad51D-XRCC2 complex)|go:"GO:0033065"(Rad51C-XRCC3 complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|mint:O43502|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|reactome:R-HSA-983231	interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020587|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|mint:Q06609|rcsb pdb:1B22|rcsb pdb:1N0W|rcsb pdb:5H1B|rcsb pdb:5H1C|rcsb pdb:5JZC|rcsb pdb:5NP7|rcsb pdb:5NWL|rcsb pdb:7C9A|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|reactome:R-HSA-8953750|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0042148"(strand invasion)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051106"(positive regulation of DNA ligation)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0072719"(cellular response to cisplatin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072757"(cellular response to camptothecin)|go:"GO:1904631"(response to glucoside)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|go:"GO:1990426"(mitotic recombination-dependent replication fork processing)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010995(DNA repair Rad51/transcription factor NusA, alpha-helical)|interpro:IPR011941(DNA repair protein RAD51)|ensembl:ENSG00000051180(gene)|ensembl:ENST00000267868(transcript)|ensembl:ENST00000532743(transcript)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000800"(lateral element)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006312"(mitotic recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016605"(PML body)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0005815"(microtubule organizing center)|refseq:NP_001157742.1|refseq:NP_002866.2|refseq:NP_597994.3|refseq:XP_011520159.1|refseq:XP_011520160.1|refseq:XP_011520161.1|refseq:XP_011520162.1|refseq:XP_011520163.1|refseq:NP_001157741.1|refseq:XP_006720689.1|dip:DIP-462N	-	-	-	figure legend:Supplement. 5|comment:Depletion of RAD51 does not change levels of CoIPed PALB2 and BRCA2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2014/02/06	2015/12/03	rogid:z3aviP3W7VXZGS7njC09B9M+fZs9606	rogid:B7WPMU7tZuNcA2qjsTR+7i/OwFw9606	intact-crc:C9C7D8DAC0A6982D|rigid:aGUgRn+HEEpIIUshIHSPnxYT7vY	false	his tag:n-n|flag tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O43502	uniprotkb:Q86YC2	intact:EBI-2267048|uniprotkb:Q3B783|uniprotkb:O43503|intact:EBI-28969664|ensembl:ENSP00000336701	intact:EBI-1222653|uniprotkb:Q8N7Y6|uniprotkb:Q8ND31|uniprotkb:Q9H6W1|uniprotkb:A6NIE1|ensembl:ENSP00000261584	psi-mi:ra51c_human(display_long)|uniprotkb:RAD51 homolog C(gene name synonym)|uniprotkb:RAD51C(gene name)|psi-mi:RAD51C(display_short)|uniprotkb:RAD51L2(gene name synonym)|uniprotkb:RAD51-like protein 2(gene name synonym)	psi-mi:palb2_human(display_long)|uniprotkb:PALB2(gene name)|psi-mi:PALB2(display_short)|uniprotkb:FANCN(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Park et al. (2013)	imex:IM-22188|pubmed:24141787	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9119758|imex:IM-22188-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000336701|ensembl:ENST00000421782|ensembl:ENSP00000391450|refseq:NP_002867.1|refseq:NP_478123.1|dip:DIP-41247N|ensembl:ENSG00000108384(gene)|ensembl:ENST00000337432(transcript)|go:"GO:0000707"(meiotic DNA recombinase assembly)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007066"(female meiosis sister chromatid cohesion)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030054"(cell junction)|go:"GO:0033063"(Rad51B-Rad51C-Rad51D-XRCC2 complex)|go:"GO:0033065"(Rad51C-XRCC3 complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|mint:O43502|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|reactome:R-HSA-983231	refseq:NP_078951.2|dip:DIP-38427N|ensembl:ENSG00000083093(gene)|ensembl:ENST00000261584(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001756"(somitogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007498"(mesoderm development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0048568"(embryonic organ development)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031920|interpro:IPR036322|interpro:IPR042417|mint:Q86YC2|rcsb pdb:2W18|rcsb pdb:3EU7|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|go:"GO:0001833"(inner cell mass cell proliferation)	-	-	-	figure legend:Supplement. 5|comment:Depletion of RAD51 does not change levels of CoIPed PALB2 and BRCA2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2014/02/06	2015/12/03	rogid:z3aviP3W7VXZGS7njC09B9M+fZs9606	rogid:/CusSIimN2s+1JZ83gI0GtaHdz09606	intact-crc:C9C7D8DAC0A6982D|rigid:aGUgRn+HEEpIIUshIHSPnxYT7vY	false	his tag:n-n|flag tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O43502	uniprotkb:P51587	intact:EBI-2267048|uniprotkb:Q3B783|uniprotkb:O43503|intact:EBI-28969664|ensembl:ENSP00000336701	intact:EBI-79792|ensembl:ENSP00000369497|ensembl:ENSP00000439902|uniprotkb:Q5TBJ7|uniprotkb:O00183|uniprotkb:O15008|uniprotkb:Q13879	psi-mi:ra51c_human(display_long)|uniprotkb:RAD51 homolog C(gene name synonym)|uniprotkb:RAD51C(gene name)|psi-mi:RAD51C(display_short)|uniprotkb:RAD51L2(gene name synonym)|uniprotkb:RAD51-like protein 2(gene name synonym)	psi-mi:brca2_human(display_long)|uniprotkb:BRCA2(gene name)|psi-mi:BRCA2(display_short)|uniprotkb:FANCD1(gene name synonym)|uniprotkb:FACD(gene name synonym)|uniprotkb:Fanconi anemia group D1 protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Park et al. (2013)	imex:IM-22188|pubmed:24141787	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9119758|imex:IM-22188-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000336701|ensembl:ENST00000421782|ensembl:ENSP00000391450|refseq:NP_002867.1|refseq:NP_478123.1|dip:DIP-41247N|ensembl:ENSG00000108384(gene)|ensembl:ENST00000337432(transcript)|go:"GO:0000707"(meiotic DNA recombinase assembly)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007066"(female meiosis sister chromatid cohesion)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030054"(cell junction)|go:"GO:0033063"(Rad51B-Rad51C-Rad51D-XRCC2 complex)|go:"GO:0033065"(Rad51C-XRCC3 complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|mint:O43502|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|reactome:R-HSA-983231	ensembl:ENSG00000139618(gene)|ensembl:ENST00000380152(transcript)|ensembl:ENST00000544455(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007569"(cell aging)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008585"(female gonad development)|go:"GO:0010165"(response to X-ray)|go:"GO:0010225"(response to UV-C)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030141"(secretory granule)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033593"(BRCA2-MAGE-D1 complex)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048478"(replication fork protection)|go:"GO:0051298"(centrosome duplication)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:1990426"(mitotic recombination-dependent replication fork processing)|interpro:IPR002093(BRCA2 repeat)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR015187(BRCA2, oligonucleotide/oligosaccharide-binding 1)|interpro:IPR015188(BRCA2, oligonucleotide/oligosaccharide-binding 3)|interpro:IPR015205(Tower)|interpro:IPR015252(BRCA2, helical)|interpro:IPR015525(Breast cancer type 2 susceptibility protein)|interpro:IPR036315|mint:P51587|rcsb pdb:1N0W|rcsb pdb:3EU7|rcsb pdb:6GY2|go:"GO:0007141"(male meiosis I)|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|rcsb pdb:6HQU|refseq:NP_000050.2|dip:DIP-24214N	-	-	-	figure legend:Supplement. 5|comment:Depletion of RAD51 does not change levels of CoIPed PALB2 and BRCA2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2014/02/06	2015/12/03	rogid:z3aviP3W7VXZGS7njC09B9M+fZs9606	rogid:GvNlXMFXTHiRgOGT5EBlQUVh/+k9606	intact-crc:C9C7D8DAC0A6982D|rigid:aGUgRn+HEEpIIUshIHSPnxYT7vY	false	his tag:n-n|flag tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O43502	uniprotkb:Q06609	intact:EBI-2267048|uniprotkb:Q3B783|uniprotkb:O43503|intact:EBI-28969664|ensembl:ENSP00000336701	intact:EBI-297202|uniprotkb:Q6FHX9|ensembl:ENSP00000267868|ensembl:ENSP00000433924|uniprotkb:B0FXP0|uniprotkb:Q9BV60|intact:EBI-1059207|uniprotkb:B2R8T6|uniprotkb:Q6ZNA8	psi-mi:ra51c_human(display_long)|uniprotkb:RAD51 homolog C(gene name synonym)|uniprotkb:RAD51C(gene name)|psi-mi:RAD51C(display_short)|uniprotkb:RAD51L2(gene name synonym)|uniprotkb:RAD51-like protein 2(gene name synonym)	psi-mi:rad51_human(display_long)|uniprotkb:RAD51(gene name)|psi-mi:RAD51(display_short)|uniprotkb:RAD51A(gene name synonym)|uniprotkb:RECA(gene name synonym)|uniprotkb:RAD51 homolog A(gene name synonym)	psi-mi:"MI:0858"(immunodepleted coimmunoprecipitation)	Park et al. (2013)	imex:IM-22188|pubmed:24141787	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9118502|imex:IM-22188-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000336701|ensembl:ENST00000421782|ensembl:ENSP00000391450|refseq:NP_002867.1|refseq:NP_478123.1|dip:DIP-41247N|ensembl:ENSG00000108384(gene)|ensembl:ENST00000337432(transcript)|go:"GO:0000707"(meiotic DNA recombinase assembly)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007066"(female meiosis sister chromatid cohesion)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030054"(cell junction)|go:"GO:0033063"(Rad51B-Rad51C-Rad51D-XRCC2 complex)|go:"GO:0033065"(Rad51C-XRCC3 complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|mint:O43502|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|reactome:R-HSA-983231	interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020587|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|mint:Q06609|rcsb pdb:1B22|rcsb pdb:1N0W|rcsb pdb:5H1B|rcsb pdb:5H1C|rcsb pdb:5JZC|rcsb pdb:5NP7|rcsb pdb:5NWL|rcsb pdb:7C9A|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|reactome:R-HSA-8953750|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0042148"(strand invasion)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051106"(positive regulation of DNA ligation)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0072719"(cellular response to cisplatin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072757"(cellular response to camptothecin)|go:"GO:1904631"(response to glucoside)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|go:"GO:1990426"(mitotic recombination-dependent replication fork processing)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010995(DNA repair Rad51/transcription factor NusA, alpha-helical)|interpro:IPR011941(DNA repair protein RAD51)|ensembl:ENSG00000051180(gene)|ensembl:ENST00000267868(transcript)|ensembl:ENST00000532743(transcript)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000800"(lateral element)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006312"(mitotic recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016605"(PML body)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0005815"(microtubule organizing center)|refseq:NP_001157742.1|refseq:NP_002866.2|refseq:NP_597994.3|refseq:XP_011520159.1|refseq:XP_011520160.1|refseq:XP_011520161.1|refseq:XP_011520162.1|refseq:XP_011520163.1|refseq:NP_001157741.1|refseq:XP_006720689.1|dip:DIP-462N	-	-	-	figure legend:1D|comment:Less PALB2, BRCA2 and RAD51  co-immunoprecipitated with HF-RAD51C as a result of the immunodepletion of RAD51.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2014/02/06	2015/12/03	rogid:z3aviP3W7VXZGS7njC09B9M+fZs9606	rogid:B7WPMU7tZuNcA2qjsTR+7i/OwFw9606	intact-crc:92CCFF671C2BA85F|rigid:aGUgRn+HEEpIIUshIHSPnxYT7vY	false	flag tag:n-n|his tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O43502	uniprotkb:P51587	intact:EBI-2267048|uniprotkb:Q3B783|uniprotkb:O43503|intact:EBI-28969664|ensembl:ENSP00000336701	intact:EBI-79792|ensembl:ENSP00000369497|ensembl:ENSP00000439902|uniprotkb:Q5TBJ7|uniprotkb:O00183|uniprotkb:O15008|uniprotkb:Q13879	psi-mi:ra51c_human(display_long)|uniprotkb:RAD51 homolog C(gene name synonym)|uniprotkb:RAD51C(gene name)|psi-mi:RAD51C(display_short)|uniprotkb:RAD51L2(gene name synonym)|uniprotkb:RAD51-like protein 2(gene name synonym)	psi-mi:brca2_human(display_long)|uniprotkb:BRCA2(gene name)|psi-mi:BRCA2(display_short)|uniprotkb:FANCD1(gene name synonym)|uniprotkb:FACD(gene name synonym)|uniprotkb:Fanconi anemia group D1 protein(gene name synonym)	psi-mi:"MI:0858"(immunodepleted coimmunoprecipitation)	Park et al. (2013)	imex:IM-22188|pubmed:24141787	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9118502|imex:IM-22188-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000336701|ensembl:ENST00000421782|ensembl:ENSP00000391450|refseq:NP_002867.1|refseq:NP_478123.1|dip:DIP-41247N|ensembl:ENSG00000108384(gene)|ensembl:ENST00000337432(transcript)|go:"GO:0000707"(meiotic DNA recombinase assembly)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007066"(female meiosis sister chromatid cohesion)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030054"(cell junction)|go:"GO:0033063"(Rad51B-Rad51C-Rad51D-XRCC2 complex)|go:"GO:0033065"(Rad51C-XRCC3 complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|mint:O43502|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|reactome:R-HSA-983231	ensembl:ENSG00000139618(gene)|ensembl:ENST00000380152(transcript)|ensembl:ENST00000544455(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007569"(cell aging)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008585"(female gonad development)|go:"GO:0010165"(response to X-ray)|go:"GO:0010225"(response to UV-C)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030141"(secretory granule)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033593"(BRCA2-MAGE-D1 complex)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048478"(replication fork protection)|go:"GO:0051298"(centrosome duplication)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:1990426"(mitotic recombination-dependent replication fork processing)|interpro:IPR002093(BRCA2 repeat)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR015187(BRCA2, oligonucleotide/oligosaccharide-binding 1)|interpro:IPR015188(BRCA2, oligonucleotide/oligosaccharide-binding 3)|interpro:IPR015205(Tower)|interpro:IPR015252(BRCA2, helical)|interpro:IPR015525(Breast cancer type 2 susceptibility protein)|interpro:IPR036315|mint:P51587|rcsb pdb:1N0W|rcsb pdb:3EU7|rcsb pdb:6GY2|go:"GO:0007141"(male meiosis I)|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|rcsb pdb:6HQU|refseq:NP_000050.2|dip:DIP-24214N	-	-	-	figure legend:1D|comment:Less PALB2, BRCA2 and RAD51  co-immunoprecipitated with HF-RAD51C as a result of the immunodepletion of RAD51.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2014/02/06	2015/12/03	rogid:z3aviP3W7VXZGS7njC09B9M+fZs9606	rogid:GvNlXMFXTHiRgOGT5EBlQUVh/+k9606	intact-crc:92CCFF671C2BA85F|rigid:aGUgRn+HEEpIIUshIHSPnxYT7vY	false	flag tag:n-n|his tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O43502	uniprotkb:Q86YC2	intact:EBI-2267048|uniprotkb:Q3B783|uniprotkb:O43503|intact:EBI-28969664|ensembl:ENSP00000336701	intact:EBI-1222653|uniprotkb:Q8N7Y6|uniprotkb:Q8ND31|uniprotkb:Q9H6W1|uniprotkb:A6NIE1|ensembl:ENSP00000261584	psi-mi:ra51c_human(display_long)|uniprotkb:RAD51 homolog C(gene name synonym)|uniprotkb:RAD51C(gene name)|psi-mi:RAD51C(display_short)|uniprotkb:RAD51L2(gene name synonym)|uniprotkb:RAD51-like protein 2(gene name synonym)	psi-mi:palb2_human(display_long)|uniprotkb:PALB2(gene name)|psi-mi:PALB2(display_short)|uniprotkb:FANCN(gene name synonym)	psi-mi:"MI:0858"(immunodepleted coimmunoprecipitation)	Park et al. (2013)	imex:IM-22188|pubmed:24141787	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9118502|imex:IM-22188-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000336701|ensembl:ENST00000421782|ensembl:ENSP00000391450|refseq:NP_002867.1|refseq:NP_478123.1|dip:DIP-41247N|ensembl:ENSG00000108384(gene)|ensembl:ENST00000337432(transcript)|go:"GO:0000707"(meiotic DNA recombinase assembly)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007066"(female meiosis sister chromatid cohesion)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030054"(cell junction)|go:"GO:0033063"(Rad51B-Rad51C-Rad51D-XRCC2 complex)|go:"GO:0033065"(Rad51C-XRCC3 complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|mint:O43502|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|reactome:R-HSA-983231	refseq:NP_078951.2|dip:DIP-38427N|ensembl:ENSG00000083093(gene)|ensembl:ENST00000261584(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001756"(somitogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007498"(mesoderm development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0048568"(embryonic organ development)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031920|interpro:IPR036322|interpro:IPR042417|mint:Q86YC2|rcsb pdb:2W18|rcsb pdb:3EU7|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|go:"GO:0001833"(inner cell mass cell proliferation)	-	-	-	figure legend:1D|comment:Less PALB2, BRCA2 and RAD51  co-immunoprecipitated with HF-RAD51C as a result of the immunodepletion of RAD51.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2014/02/06	2015/12/03	rogid:z3aviP3W7VXZGS7njC09B9M+fZs9606	rogid:/CusSIimN2s+1JZ83gI0GtaHdz09606	intact-crc:92CCFF671C2BA85F|rigid:aGUgRn+HEEpIIUshIHSPnxYT7vY	false	flag tag:n-n|his tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q86YC2	uniprotkb:O43502	intact:EBI-1222653|uniprotkb:Q8N7Y6|uniprotkb:Q8ND31|uniprotkb:Q9H6W1|uniprotkb:A6NIE1|ensembl:ENSP00000261584	intact:EBI-2267048|uniprotkb:Q3B783|uniprotkb:O43503|intact:EBI-28969664|ensembl:ENSP00000336701	psi-mi:palb2_human(display_long)|uniprotkb:PALB2(gene name)|psi-mi:PALB2(display_short)|uniprotkb:FANCN(gene name synonym)	psi-mi:ra51c_human(display_long)|uniprotkb:RAD51 homolog C(gene name synonym)|uniprotkb:RAD51C(gene name)|psi-mi:RAD51C(display_short)|uniprotkb:RAD51L2(gene name synonym)|uniprotkb:RAD51-like protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Park et al. (2013)	imex:IM-22188|pubmed:24141787	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9118591|imex:IM-22188-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_078951.2|dip:DIP-38427N|ensembl:ENSG00000083093(gene)|ensembl:ENST00000261584(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001756"(somitogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007498"(mesoderm development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0048568"(embryonic organ development)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031920|interpro:IPR036322|interpro:IPR042417|mint:Q86YC2|rcsb pdb:2W18|rcsb pdb:3EU7|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|go:"GO:0001833"(inner cell mass cell proliferation)	ensembl:ENSP00000336701|ensembl:ENST00000421782|ensembl:ENSP00000391450|refseq:NP_002867.1|refseq:NP_478123.1|dip:DIP-41247N|ensembl:ENSG00000108384(gene)|ensembl:ENST00000337432(transcript)|go:"GO:0000707"(meiotic DNA recombinase assembly)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007066"(female meiosis sister chromatid cohesion)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030054"(cell junction)|go:"GO:0033063"(Rad51B-Rad51C-Rad51D-XRCC2 complex)|go:"GO:0033065"(Rad51C-XRCC3 complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|mint:O43502|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|reactome:R-HSA-983231	-	-	-	figure legend:2B|comment:"The PALB2 c-terminal deletion construct aa 1-150 precipitated small amounts of RAD51 (but no BRCA2, RAD51C or RAD51D)"|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2014/02/06	2015/12/03	rogid:/CusSIimN2s+1JZ83gI0GtaHdz09606	rogid:z3aviP3W7VXZGS7njC09B9M+fZs9606	intact-crc:AB0DE7B3CE06F175|rigid:aGUgRn+HEEpIIUshIHSPnxYT7vY	false	flag tag:n-n|his tag:n-n|necessary binding region:551-1186	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q86YC2	uniprotkb:Q06609	intact:EBI-1222653|uniprotkb:Q8N7Y6|uniprotkb:Q8ND31|uniprotkb:Q9H6W1|uniprotkb:A6NIE1|ensembl:ENSP00000261584	intact:EBI-297202|uniprotkb:Q6FHX9|ensembl:ENSP00000267868|ensembl:ENSP00000433924|uniprotkb:B0FXP0|uniprotkb:Q9BV60|intact:EBI-1059207|uniprotkb:B2R8T6|uniprotkb:Q6ZNA8	psi-mi:palb2_human(display_long)|uniprotkb:PALB2(gene name)|psi-mi:PALB2(display_short)|uniprotkb:FANCN(gene name synonym)	psi-mi:rad51_human(display_long)|uniprotkb:RAD51(gene name)|psi-mi:RAD51(display_short)|uniprotkb:RAD51A(gene name synonym)|uniprotkb:RECA(gene name synonym)|uniprotkb:RAD51 homolog A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Park et al. (2013)	imex:IM-22188|pubmed:24141787	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9118591|imex:IM-22188-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_078951.2|dip:DIP-38427N|ensembl:ENSG00000083093(gene)|ensembl:ENST00000261584(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001756"(somitogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007498"(mesoderm development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0048568"(embryonic organ development)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031920|interpro:IPR036322|interpro:IPR042417|mint:Q86YC2|rcsb pdb:2W18|rcsb pdb:3EU7|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|go:"GO:0001833"(inner cell mass cell proliferation)	interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020587|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|mint:Q06609|rcsb pdb:1B22|rcsb pdb:1N0W|rcsb pdb:5H1B|rcsb pdb:5H1C|rcsb pdb:5JZC|rcsb pdb:5NP7|rcsb pdb:5NWL|rcsb pdb:7C9A|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|reactome:R-HSA-8953750|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0042148"(strand invasion)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051106"(positive regulation of DNA ligation)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0072719"(cellular response to cisplatin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072757"(cellular response to camptothecin)|go:"GO:1904631"(response to glucoside)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|go:"GO:1990426"(mitotic recombination-dependent replication fork processing)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010995(DNA repair Rad51/transcription factor NusA, alpha-helical)|interpro:IPR011941(DNA repair protein RAD51)|ensembl:ENSG00000051180(gene)|ensembl:ENST00000267868(transcript)|ensembl:ENST00000532743(transcript)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000800"(lateral element)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006312"(mitotic recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016605"(PML body)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0005815"(microtubule organizing center)|refseq:NP_001157742.1|refseq:NP_002866.2|refseq:NP_597994.3|refseq:XP_011520159.1|refseq:XP_011520160.1|refseq:XP_011520161.1|refseq:XP_011520162.1|refseq:XP_011520163.1|refseq:NP_001157741.1|refseq:XP_006720689.1|dip:DIP-462N	-	-	-	figure legend:2B|comment:"The PALB2 c-terminal deletion construct aa 1-150 precipitated small amounts of RAD51 (but no BRCA2, RAD51C or RAD51D)"|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2014/02/06	2015/12/03	rogid:/CusSIimN2s+1JZ83gI0GtaHdz09606	rogid:B7WPMU7tZuNcA2qjsTR+7i/OwFw9606	intact-crc:AB0DE7B3CE06F175|rigid:aGUgRn+HEEpIIUshIHSPnxYT7vY	false	flag tag:n-n|his tag:n-n|necessary binding region:551-1186	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q86YC2	uniprotkb:P51587	intact:EBI-1222653|uniprotkb:Q8N7Y6|uniprotkb:Q8ND31|uniprotkb:Q9H6W1|uniprotkb:A6NIE1|ensembl:ENSP00000261584	intact:EBI-79792|ensembl:ENSP00000369497|ensembl:ENSP00000439902|uniprotkb:Q5TBJ7|uniprotkb:O00183|uniprotkb:O15008|uniprotkb:Q13879	psi-mi:palb2_human(display_long)|uniprotkb:PALB2(gene name)|psi-mi:PALB2(display_short)|uniprotkb:FANCN(gene name synonym)	psi-mi:brca2_human(display_long)|uniprotkb:BRCA2(gene name)|psi-mi:BRCA2(display_short)|uniprotkb:FANCD1(gene name synonym)|uniprotkb:FACD(gene name synonym)|uniprotkb:Fanconi anemia group D1 protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Park et al. (2013)	imex:IM-22188|pubmed:24141787	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9118591|imex:IM-22188-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_078951.2|dip:DIP-38427N|ensembl:ENSG00000083093(gene)|ensembl:ENST00000261584(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001756"(somitogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007498"(mesoderm development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0048568"(embryonic organ development)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031920|interpro:IPR036322|interpro:IPR042417|mint:Q86YC2|rcsb pdb:2W18|rcsb pdb:3EU7|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|go:"GO:0001833"(inner cell mass cell proliferation)	ensembl:ENSG00000139618(gene)|ensembl:ENST00000380152(transcript)|ensembl:ENST00000544455(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007569"(cell aging)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008585"(female gonad development)|go:"GO:0010165"(response to X-ray)|go:"GO:0010225"(response to UV-C)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030141"(secretory granule)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033593"(BRCA2-MAGE-D1 complex)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048478"(replication fork protection)|go:"GO:0051298"(centrosome duplication)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:1990426"(mitotic recombination-dependent replication fork processing)|interpro:IPR002093(BRCA2 repeat)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR015187(BRCA2, oligonucleotide/oligosaccharide-binding 1)|interpro:IPR015188(BRCA2, oligonucleotide/oligosaccharide-binding 3)|interpro:IPR015205(Tower)|interpro:IPR015252(BRCA2, helical)|interpro:IPR015525(Breast cancer type 2 susceptibility protein)|interpro:IPR036315|mint:P51587|rcsb pdb:1N0W|rcsb pdb:3EU7|rcsb pdb:6GY2|go:"GO:0007141"(male meiosis I)|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|rcsb pdb:6HQU|refseq:NP_000050.2|dip:DIP-24214N	-	-	-	figure legend:2B|comment:"The PALB2 c-terminal deletion construct aa 1-150 precipitated small amounts of RAD51 (but no BRCA2, RAD51C or RAD51D)"|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2014/02/06	2015/12/03	rogid:/CusSIimN2s+1JZ83gI0GtaHdz09606	rogid:GvNlXMFXTHiRgOGT5EBlQUVh/+k9606	intact-crc:AB0DE7B3CE06F175|rigid:aGUgRn+HEEpIIUshIHSPnxYT7vY	false	flag tag:n-n|his tag:n-n|necessary binding region:551-1186	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O43542	uniprotkb:O43502	intact:EBI-2849976|uniprotkb:Q9BU18|uniprotkb:O43568|ensembl:ENSP00000343392|ensembl:ENSP00000451362|ensembl:ENSP00000451974|ensembl:ENSP00000452598	intact:EBI-2267048|uniprotkb:Q3B783|uniprotkb:O43503|intact:EBI-28969664|ensembl:ENSP00000336701	psi-mi:xrcc3_human(display_long)|uniprotkb:XRCC3(gene name)|psi-mi:XRCC3(display_short)|uniprotkb:X-ray repair cross-complementing protein 3(gene name synonym)	psi-mi:ra51c_human(display_long)|uniprotkb:RAD51 homolog C(gene name synonym)|uniprotkb:RAD51C(gene name)|psi-mi:RAD51C(display_short)|uniprotkb:RAD51L2(gene name synonym)|uniprotkb:RAD51-like protein 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Park et al. (2013)	imex:IM-22188|pubmed:24141787	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9119744|imex:IM-22188-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011535440.1|refseq:NP_001093588.1|refseq:NP_001093589.1|refseq:NP_005423.1|refseq:XP_005268103.1|dip:DIP-42016N|ensembl:ENSG00000126215(gene)|ensembl:ENST00000352127(transcript)|ensembl:ENST00000553264(transcript)|ensembl:ENST00000554913(transcript)|ensembl:ENST00000555055(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0010033"(response to organic substance)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0033065"(Rad51C-XRCC3 complex)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0045003"(double-strand break repair via synthesis-dependent strand annealing)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071140"(resolution of mitotic recombination intermediates)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:0090656"(t-circle formation)|go:"GO:0090657"(telomeric loop disassembly)|go:"GO:0090737"(telomere maintenance via telomere trimming)|interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|go:"GO:0005524"(ATP binding)	ensembl:ENSP00000336701|ensembl:ENST00000421782|ensembl:ENSP00000391450|refseq:NP_002867.1|refseq:NP_478123.1|dip:DIP-41247N|ensembl:ENSG00000108384(gene)|ensembl:ENST00000337432(transcript)|go:"GO:0000707"(meiotic DNA recombinase assembly)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007066"(female meiosis sister chromatid cohesion)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030054"(cell junction)|go:"GO:0033063"(Rad51B-Rad51C-Rad51D-XRCC2 complex)|go:"GO:0033065"(Rad51C-XRCC3 complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|mint:O43502|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|reactome:R-HSA-983231	-	-	-	figure legend:Supplement. 2|comment:Levels of CoIPed RAD51C are lower in cells reconstituted with PALB2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-eufa1341)|taxid:9606(Homo sapiens)	-	2014/02/06	2015/12/03	rogid:3vDLDeKRnmV6Wg9dK2yMbIRqzVk9606	rogid:z3aviP3W7VXZGS7njC09B9M+fZs9606	intact-crc:9374D5FF7BFE5FD5|rigid:sr0xpEAg16hEZ5USNQ6Gd6psuVw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O43542	uniprotkb:Q86YC2	intact:EBI-2849976|uniprotkb:Q9BU18|uniprotkb:O43568|ensembl:ENSP00000343392|ensembl:ENSP00000451362|ensembl:ENSP00000451974|ensembl:ENSP00000452598	intact:EBI-1222653|uniprotkb:Q8N7Y6|uniprotkb:Q8ND31|uniprotkb:Q9H6W1|uniprotkb:A6NIE1|ensembl:ENSP00000261584	psi-mi:xrcc3_human(display_long)|uniprotkb:XRCC3(gene name)|psi-mi:XRCC3(display_short)|uniprotkb:X-ray repair cross-complementing protein 3(gene name synonym)	psi-mi:palb2_human(display_long)|uniprotkb:PALB2(gene name)|psi-mi:PALB2(display_short)|uniprotkb:FANCN(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Park et al. (2013)	imex:IM-22188|pubmed:24141787	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9119744|imex:IM-22188-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011535440.1|refseq:NP_001093588.1|refseq:NP_001093589.1|refseq:NP_005423.1|refseq:XP_005268103.1|dip:DIP-42016N|ensembl:ENSG00000126215(gene)|ensembl:ENST00000352127(transcript)|ensembl:ENST00000553264(transcript)|ensembl:ENST00000554913(transcript)|ensembl:ENST00000555055(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0010033"(response to organic substance)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0033065"(Rad51C-XRCC3 complex)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0045003"(double-strand break repair via synthesis-dependent strand annealing)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071140"(resolution of mitotic recombination intermediates)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:0090656"(t-circle formation)|go:"GO:0090657"(telomeric loop disassembly)|go:"GO:0090737"(telomere maintenance via telomere trimming)|interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|go:"GO:0005524"(ATP binding)	refseq:NP_078951.2|dip:DIP-38427N|ensembl:ENSG00000083093(gene)|ensembl:ENST00000261584(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001756"(somitogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007498"(mesoderm development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0048568"(embryonic organ development)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031920|interpro:IPR036322|interpro:IPR042417|mint:Q86YC2|rcsb pdb:2W18|rcsb pdb:3EU7|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|go:"GO:0001833"(inner cell mass cell proliferation)	-	-	-	figure legend:Supplement. 2|comment:Levels of CoIPed RAD51C are lower in cells reconstituted with PALB2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-eufa1341)|taxid:9606(Homo sapiens)	-	2014/02/06	2015/12/03	rogid:3vDLDeKRnmV6Wg9dK2yMbIRqzVk9606	rogid:/CusSIimN2s+1JZ83gI0GtaHdz09606	intact-crc:9374D5FF7BFE5FD5|rigid:sr0xpEAg16hEZ5USNQ6Gd6psuVw	false	-	ha tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O43542	uniprotkb:P51587	intact:EBI-2849976|uniprotkb:Q9BU18|uniprotkb:O43568|ensembl:ENSP00000343392|ensembl:ENSP00000451362|ensembl:ENSP00000451974|ensembl:ENSP00000452598	intact:EBI-79792|ensembl:ENSP00000369497|ensembl:ENSP00000439902|uniprotkb:Q5TBJ7|uniprotkb:O00183|uniprotkb:O15008|uniprotkb:Q13879	psi-mi:xrcc3_human(display_long)|uniprotkb:XRCC3(gene name)|psi-mi:XRCC3(display_short)|uniprotkb:X-ray repair cross-complementing protein 3(gene name synonym)	psi-mi:brca2_human(display_long)|uniprotkb:BRCA2(gene name)|psi-mi:BRCA2(display_short)|uniprotkb:FANCD1(gene name synonym)|uniprotkb:FACD(gene name synonym)|uniprotkb:Fanconi anemia group D1 protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Park et al. (2013)	imex:IM-22188|pubmed:24141787	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9119744|imex:IM-22188-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011535440.1|refseq:NP_001093588.1|refseq:NP_001093589.1|refseq:NP_005423.1|refseq:XP_005268103.1|dip:DIP-42016N|ensembl:ENSG00000126215(gene)|ensembl:ENST00000352127(transcript)|ensembl:ENST00000553264(transcript)|ensembl:ENST00000554913(transcript)|ensembl:ENST00000555055(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0010033"(response to organic substance)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0033065"(Rad51C-XRCC3 complex)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0045003"(double-strand break repair via synthesis-dependent strand annealing)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071140"(resolution of mitotic recombination intermediates)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:0090656"(t-circle formation)|go:"GO:0090657"(telomeric loop disassembly)|go:"GO:0090737"(telomere maintenance via telomere trimming)|interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|go:"GO:0005524"(ATP binding)	ensembl:ENSG00000139618(gene)|ensembl:ENST00000380152(transcript)|ensembl:ENST00000544455(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007569"(cell aging)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008585"(female gonad development)|go:"GO:0010165"(response to X-ray)|go:"GO:0010225"(response to UV-C)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030141"(secretory granule)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033593"(BRCA2-MAGE-D1 complex)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048478"(replication fork protection)|go:"GO:0051298"(centrosome duplication)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:1990426"(mitotic recombination-dependent replication fork processing)|interpro:IPR002093(BRCA2 repeat)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR015187(BRCA2, oligonucleotide/oligosaccharide-binding 1)|interpro:IPR015188(BRCA2, oligonucleotide/oligosaccharide-binding 3)|interpro:IPR015205(Tower)|interpro:IPR015252(BRCA2, helical)|interpro:IPR015525(Breast cancer type 2 susceptibility protein)|interpro:IPR036315|mint:P51587|rcsb pdb:1N0W|rcsb pdb:3EU7|rcsb pdb:6GY2|go:"GO:0007141"(male meiosis I)|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|rcsb pdb:6HQU|refseq:NP_000050.2|dip:DIP-24214N	-	-	-	figure legend:Supplement. 2|comment:Levels of CoIPed RAD51C are lower in cells reconstituted with PALB2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-eufa1341)|taxid:9606(Homo sapiens)	-	2014/02/06	2015/12/03	rogid:3vDLDeKRnmV6Wg9dK2yMbIRqzVk9606	rogid:GvNlXMFXTHiRgOGT5EBlQUVh/+k9606	intact-crc:9374D5FF7BFE5FD5|rigid:sr0xpEAg16hEZ5USNQ6Gd6psuVw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O43502	uniprotkb:Q06609	intact:EBI-2267048|uniprotkb:Q3B783|uniprotkb:O43503|intact:EBI-28969664|ensembl:ENSP00000336701	intact:EBI-297202|uniprotkb:Q6FHX9|ensembl:ENSP00000267868|ensembl:ENSP00000433924|uniprotkb:B0FXP0|uniprotkb:Q9BV60|intact:EBI-1059207|uniprotkb:B2R8T6|uniprotkb:Q6ZNA8	psi-mi:ra51c_human(display_long)|uniprotkb:RAD51 homolog C(gene name synonym)|uniprotkb:RAD51C(gene name)|psi-mi:RAD51C(display_short)|uniprotkb:RAD51L2(gene name synonym)|uniprotkb:RAD51-like protein 2(gene name synonym)	psi-mi:rad51_human(display_long)|uniprotkb:RAD51(gene name)|psi-mi:RAD51(display_short)|uniprotkb:RAD51A(gene name synonym)|uniprotkb:RECA(gene name synonym)|uniprotkb:RAD51 homolog A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Park et al. (2013)	imex:IM-22188|pubmed:24141787	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9118355|imex:IM-22188-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000336701|ensembl:ENST00000421782|ensembl:ENSP00000391450|refseq:NP_002867.1|refseq:NP_478123.1|dip:DIP-41247N|ensembl:ENSG00000108384(gene)|ensembl:ENST00000337432(transcript)|go:"GO:0000707"(meiotic DNA recombinase assembly)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007066"(female meiosis sister chromatid cohesion)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030054"(cell junction)|go:"GO:0033063"(Rad51B-Rad51C-Rad51D-XRCC2 complex)|go:"GO:0033065"(Rad51C-XRCC3 complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|mint:O43502|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|reactome:R-HSA-983231	interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020587|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|mint:Q06609|rcsb pdb:1B22|rcsb pdb:1N0W|rcsb pdb:5H1B|rcsb pdb:5H1C|rcsb pdb:5JZC|rcsb pdb:5NP7|rcsb pdb:5NWL|rcsb pdb:7C9A|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|reactome:R-HSA-8953750|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0042148"(strand invasion)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051106"(positive regulation of DNA ligation)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0072719"(cellular response to cisplatin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072757"(cellular response to camptothecin)|go:"GO:1904631"(response to glucoside)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|go:"GO:1990426"(mitotic recombination-dependent replication fork processing)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010995(DNA repair Rad51/transcription factor NusA, alpha-helical)|interpro:IPR011941(DNA repair protein RAD51)|ensembl:ENSG00000051180(gene)|ensembl:ENST00000267868(transcript)|ensembl:ENST00000532743(transcript)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000800"(lateral element)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006312"(mitotic recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016605"(PML body)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0005815"(microtubule organizing center)|refseq:NP_001157742.1|refseq:NP_002866.2|refseq:NP_597994.3|refseq:XP_011520159.1|refseq:XP_011520160.1|refseq:XP_011520161.1|refseq:XP_011520162.1|refseq:XP_011520163.1|refseq:NP_001157741.1|refseq:XP_006720689.1|dip:DIP-462N	-	-	-	figure legend:1A|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2014/02/06	2015/12/03	rogid:z3aviP3W7VXZGS7njC09B9M+fZs9606	rogid:B7WPMU7tZuNcA2qjsTR+7i/OwFw9606	intact-crc:5DBBC3B55DBC8781|rigid:0fYMZEjW6YMt+64kqpcBJFabCW0	false	his tag:n-n|flag tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:O43502	uniprotkb:O15315	intact:EBI-2267048|uniprotkb:Q3B783|uniprotkb:O43503|intact:EBI-28969664|ensembl:ENSP00000336701	intact:EBI-2824089|uniprotkb:Q6FHX8|uniprotkb:Q86TR0|uniprotkb:O75210|uniprotkb:Q3Y4F8|uniprotkb:Q86U94|uniprotkb:Q86SY3|uniprotkb:Q86SY4|uniprotkb:Q86U93|uniprotkb:Q8N6H4|uniprotkb:Q9UPL5|uniprotkb:O60914|uniprotkb:Q86U92|ensembl:ENSP00000419471	psi-mi:ra51c_human(display_long)|uniprotkb:RAD51 homolog C(gene name synonym)|uniprotkb:RAD51C(gene name)|psi-mi:RAD51C(display_short)|uniprotkb:RAD51L2(gene name synonym)|uniprotkb:RAD51-like protein 2(gene name synonym)	psi-mi:ra51b_human(display_long)|uniprotkb:RAD51L1(gene name synonym)|uniprotkb:RAD51B(gene name)|psi-mi:RAD51B(display_short)|uniprotkb:REC2(gene name synonym)|uniprotkb:RAD51 homolog B(gene name synonym)|uniprotkb:RAD51-like protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Park et al. (2013)	imex:IM-22188|pubmed:24141787	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9118355|imex:IM-22188-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000336701|ensembl:ENST00000421782|ensembl:ENSP00000391450|refseq:NP_002867.1|refseq:NP_478123.1|dip:DIP-41247N|ensembl:ENSG00000108384(gene)|ensembl:ENST00000337432(transcript)|go:"GO:0000707"(meiotic DNA recombinase assembly)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007066"(female meiosis sister chromatid cohesion)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030054"(cell junction)|go:"GO:0033063"(Rad51B-Rad51C-Rad51D-XRCC2 complex)|go:"GO:0033065"(Rad51C-XRCC3 complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|mint:O43502|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|reactome:R-HSA-983231	refseq:NP_001308746.1|refseq:NP_002868.1|refseq:NP_598193.2|refseq:NP_598194.1|dip:DIP-41246N|ensembl:ENSG00000182185(gene)|ensembl:ENST00000487270(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001832"(blastocyst growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0033063"(Rad51B-Rad51C-Rad51D-XRCC2 complex)|go:"GO:0061053"(somite development)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020588|interpro:IPR027417|interpro:IPR030548|interpro:IPR033925|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-983231	-	-	-	figure legend:1A|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2014/02/06	2015/12/03	rogid:z3aviP3W7VXZGS7njC09B9M+fZs9606	rogid:4S4tV1ODcBs12pwNP/jgDd6wrMA9606	intact-crc:5DBBC3B55DBC8781|rigid:0fYMZEjW6YMt+64kqpcBJFabCW0	false	his tag:n-n|flag tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:O43502	uniprotkb:O75771	intact:EBI-2267048|uniprotkb:Q3B783|uniprotkb:O43503|intact:EBI-28969664|ensembl:ENSP00000336701	intact:EBI-1055693|uniprotkb:O76073|uniprotkb:O76085|uniprotkb:O94908|uniprotkb:Q9UFU5|uniprotkb:O43537|uniprotkb:O60355|uniprotkb:O75196|uniprotkb:O75847|uniprotkb:O75848|uniprotkb:E1P637|uniprotkb:B4DJU7|ensembl:ENSP00000338790|ensembl:ENSP00000378090	psi-mi:ra51c_human(display_long)|uniprotkb:RAD51 homolog C(gene name synonym)|uniprotkb:RAD51C(gene name)|psi-mi:RAD51C(display_short)|uniprotkb:RAD51L2(gene name synonym)|uniprotkb:RAD51-like protein 2(gene name synonym)	psi-mi:ra51d_human(display_long)|uniprotkb:R51H3(gene name synonym)|uniprotkb:RAD51-like protein 3(gene name synonym)|uniprotkb:TRAD(gene name synonym)|uniprotkb:RAD51D(gene name)|psi-mi:RAD51D(display_short)|uniprotkb:RAD51L3(gene name synonym)|uniprotkb:RAD51 homolog D(gene name synonym)	psi-mi:"MI:0096"(pull down)	Park et al. (2013)	imex:IM-22188|pubmed:24141787	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9118355|imex:IM-22188-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000336701|ensembl:ENST00000421782|ensembl:ENSP00000391450|refseq:NP_002867.1|refseq:NP_478123.1|dip:DIP-41247N|ensembl:ENSG00000108384(gene)|ensembl:ENST00000337432(transcript)|go:"GO:0000707"(meiotic DNA recombinase assembly)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007066"(female meiosis sister chromatid cohesion)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030054"(cell junction)|go:"GO:0033063"(Rad51B-Rad51C-Rad51D-XRCC2 complex)|go:"GO:0033065"(Rad51C-XRCC3 complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|mint:O43502|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|reactome:R-HSA-983231	refseq:NP_001136043.1|refseq:NP_002869.3|refseq:NP_598332.1|ensembl:ENSG00000185379(gene)|ensembl:ENST00000345365(transcript)|ensembl:ENST00000394589(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0033063"(Rad51B-Rad51C-Rad51D-XRCC2 complex)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0042148"(strand invasion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0043015"(gamma-tubulin binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020588|interpro:IPR027417|mint:O75771|rcsb pdb:2KZ3|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-6796648|dip:DIP-24265N	-	-	-	figure legend:1A|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2014/02/06	2015/12/03	rogid:z3aviP3W7VXZGS7njC09B9M+fZs9606	rogid:k2C+DzqcX3p4CT+b0XJ05bARvrI9606	intact-crc:5DBBC3B55DBC8781|rigid:0fYMZEjW6YMt+64kqpcBJFabCW0	false	his tag:n-n|flag tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:O43502	uniprotkb:O43543	intact:EBI-2267048|uniprotkb:Q3B783|uniprotkb:O43503|intact:EBI-28969664|ensembl:ENSP00000336701	intact:EBI-3918457|ensembl:ENSP00000352271|uniprotkb:B2R925	psi-mi:ra51c_human(display_long)|uniprotkb:RAD51 homolog C(gene name synonym)|uniprotkb:RAD51C(gene name)|psi-mi:RAD51C(display_short)|uniprotkb:RAD51L2(gene name synonym)|uniprotkb:RAD51-like protein 2(gene name synonym)	psi-mi:xrcc2_human(display_long)|uniprotkb:XRCC2(gene name)|psi-mi:XRCC2(display_short)|uniprotkb:X-ray repair cross-complementing protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Park et al. (2013)	imex:IM-22188|pubmed:24141787	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9118355|imex:IM-22188-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000336701|ensembl:ENST00000421782|ensembl:ENSP00000391450|refseq:NP_002867.1|refseq:NP_478123.1|dip:DIP-41247N|ensembl:ENSG00000108384(gene)|ensembl:ENST00000337432(transcript)|go:"GO:0000707"(meiotic DNA recombinase assembly)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007066"(female meiosis sister chromatid cohesion)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030054"(cell junction)|go:"GO:0033063"(Rad51B-Rad51C-Rad51D-XRCC2 complex)|go:"GO:0033065"(Rad51C-XRCC3 complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|mint:O43502|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|reactome:R-HSA-983231	ensembl:ENSG00000196584(gene)|ensembl:ENST00000359321(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0010165"(response to X-ray)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0033063"(Rad51B-Rad51C-Rad51D-XRCC2 complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042148"(strand invasion)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:2000269"(regulation of fibroblast apoptotic process)|interpro:IPR013632(Rad51, C-terminal)|interpro:IPR020588|interpro:IPR027417|interpro:IPR030547|mint:O43543|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|refseq:NP_005422.1|dip:DIP-24242N	-	-	-	figure legend:1A|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2014/02/06	2015/12/03	rogid:z3aviP3W7VXZGS7njC09B9M+fZs9606	rogid:sgFZ6wwKfudnc5XpIy9UaniHYsE9606	intact-crc:5DBBC3B55DBC8781|rigid:0fYMZEjW6YMt+64kqpcBJFabCW0	false	his tag:n-n|flag tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:O43502	uniprotkb:O43542	intact:EBI-2267048|uniprotkb:Q3B783|uniprotkb:O43503|intact:EBI-28969664|ensembl:ENSP00000336701	intact:EBI-2849976|uniprotkb:Q9BU18|uniprotkb:O43568|ensembl:ENSP00000343392|ensembl:ENSP00000451362|ensembl:ENSP00000451974|ensembl:ENSP00000452598	psi-mi:ra51c_human(display_long)|uniprotkb:RAD51 homolog C(gene name synonym)|uniprotkb:RAD51C(gene name)|psi-mi:RAD51C(display_short)|uniprotkb:RAD51L2(gene name synonym)|uniprotkb:RAD51-like protein 2(gene name synonym)	psi-mi:xrcc3_human(display_long)|uniprotkb:XRCC3(gene name)|psi-mi:XRCC3(display_short)|uniprotkb:X-ray repair cross-complementing protein 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Park et al. (2013)	imex:IM-22188|pubmed:24141787	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9118355|imex:IM-22188-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000336701|ensembl:ENST00000421782|ensembl:ENSP00000391450|refseq:NP_002867.1|refseq:NP_478123.1|dip:DIP-41247N|ensembl:ENSG00000108384(gene)|ensembl:ENST00000337432(transcript)|go:"GO:0000707"(meiotic DNA recombinase assembly)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007066"(female meiosis sister chromatid cohesion)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030054"(cell junction)|go:"GO:0033063"(Rad51B-Rad51C-Rad51D-XRCC2 complex)|go:"GO:0033065"(Rad51C-XRCC3 complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|mint:O43502|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|reactome:R-HSA-983231	refseq:XP_011535440.1|refseq:NP_001093588.1|refseq:NP_001093589.1|refseq:NP_005423.1|refseq:XP_005268103.1|dip:DIP-42016N|ensembl:ENSG00000126215(gene)|ensembl:ENST00000352127(transcript)|ensembl:ENST00000553264(transcript)|ensembl:ENST00000554913(transcript)|ensembl:ENST00000555055(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0010033"(response to organic substance)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0033065"(Rad51C-XRCC3 complex)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0045003"(double-strand break repair via synthesis-dependent strand annealing)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071140"(resolution of mitotic recombination intermediates)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:0090656"(t-circle formation)|go:"GO:0090657"(telomeric loop disassembly)|go:"GO:0090737"(telomere maintenance via telomere trimming)|interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|go:"GO:0005524"(ATP binding)	-	-	-	figure legend:1A|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2014/02/06	2015/12/03	rogid:z3aviP3W7VXZGS7njC09B9M+fZs9606	rogid:3vDLDeKRnmV6Wg9dK2yMbIRqzVk9606	intact-crc:5DBBC3B55DBC8781|rigid:0fYMZEjW6YMt+64kqpcBJFabCW0	false	his tag:n-n|flag tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:O43502	uniprotkb:P51587	intact:EBI-2267048|uniprotkb:Q3B783|uniprotkb:O43503|intact:EBI-28969664|ensembl:ENSP00000336701	intact:EBI-79792|ensembl:ENSP00000369497|ensembl:ENSP00000439902|uniprotkb:Q5TBJ7|uniprotkb:O00183|uniprotkb:O15008|uniprotkb:Q13879	psi-mi:ra51c_human(display_long)|uniprotkb:RAD51 homolog C(gene name synonym)|uniprotkb:RAD51C(gene name)|psi-mi:RAD51C(display_short)|uniprotkb:RAD51L2(gene name synonym)|uniprotkb:RAD51-like protein 2(gene name synonym)	psi-mi:brca2_human(display_long)|uniprotkb:BRCA2(gene name)|psi-mi:BRCA2(display_short)|uniprotkb:FANCD1(gene name synonym)|uniprotkb:FACD(gene name synonym)|uniprotkb:Fanconi anemia group D1 protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Park et al. (2013)	imex:IM-22188|pubmed:24141787	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9118355|imex:IM-22188-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000336701|ensembl:ENST00000421782|ensembl:ENSP00000391450|refseq:NP_002867.1|refseq:NP_478123.1|dip:DIP-41247N|ensembl:ENSG00000108384(gene)|ensembl:ENST00000337432(transcript)|go:"GO:0000707"(meiotic DNA recombinase assembly)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007066"(female meiosis sister chromatid cohesion)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030054"(cell junction)|go:"GO:0033063"(Rad51B-Rad51C-Rad51D-XRCC2 complex)|go:"GO:0033065"(Rad51C-XRCC3 complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|mint:O43502|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|reactome:R-HSA-983231	ensembl:ENSG00000139618(gene)|ensembl:ENST00000380152(transcript)|ensembl:ENST00000544455(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007569"(cell aging)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008585"(female gonad development)|go:"GO:0010165"(response to X-ray)|go:"GO:0010225"(response to UV-C)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030141"(secretory granule)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033593"(BRCA2-MAGE-D1 complex)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048478"(replication fork protection)|go:"GO:0051298"(centrosome duplication)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:1990426"(mitotic recombination-dependent replication fork processing)|interpro:IPR002093(BRCA2 repeat)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR015187(BRCA2, oligonucleotide/oligosaccharide-binding 1)|interpro:IPR015188(BRCA2, oligonucleotide/oligosaccharide-binding 3)|interpro:IPR015205(Tower)|interpro:IPR015252(BRCA2, helical)|interpro:IPR015525(Breast cancer type 2 susceptibility protein)|interpro:IPR036315|mint:P51587|rcsb pdb:1N0W|rcsb pdb:3EU7|rcsb pdb:6GY2|go:"GO:0007141"(male meiosis I)|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|rcsb pdb:6HQU|refseq:NP_000050.2|dip:DIP-24214N	-	-	-	figure legend:1A|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2014/02/06	2015/12/03	rogid:z3aviP3W7VXZGS7njC09B9M+fZs9606	rogid:GvNlXMFXTHiRgOGT5EBlQUVh/+k9606	intact-crc:5DBBC3B55DBC8781|rigid:0fYMZEjW6YMt+64kqpcBJFabCW0	false	his tag:n-n|flag tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:O43502	uniprotkb:Q86YC2	intact:EBI-2267048|uniprotkb:Q3B783|uniprotkb:O43503|intact:EBI-28969664|ensembl:ENSP00000336701	intact:EBI-1222653|uniprotkb:Q8N7Y6|uniprotkb:Q8ND31|uniprotkb:Q9H6W1|uniprotkb:A6NIE1|ensembl:ENSP00000261584	psi-mi:ra51c_human(display_long)|uniprotkb:RAD51 homolog C(gene name synonym)|uniprotkb:RAD51C(gene name)|psi-mi:RAD51C(display_short)|uniprotkb:RAD51L2(gene name synonym)|uniprotkb:RAD51-like protein 2(gene name synonym)	psi-mi:palb2_human(display_long)|uniprotkb:PALB2(gene name)|psi-mi:PALB2(display_short)|uniprotkb:FANCN(gene name synonym)	psi-mi:"MI:0096"(pull down)	Park et al. (2013)	imex:IM-22188|pubmed:24141787	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9118355|imex:IM-22188-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000336701|ensembl:ENST00000421782|ensembl:ENSP00000391450|refseq:NP_002867.1|refseq:NP_478123.1|dip:DIP-41247N|ensembl:ENSG00000108384(gene)|ensembl:ENST00000337432(transcript)|go:"GO:0000707"(meiotic DNA recombinase assembly)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007066"(female meiosis sister chromatid cohesion)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030054"(cell junction)|go:"GO:0033063"(Rad51B-Rad51C-Rad51D-XRCC2 complex)|go:"GO:0033065"(Rad51C-XRCC3 complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|mint:O43502|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|reactome:R-HSA-983231	refseq:NP_078951.2|dip:DIP-38427N|ensembl:ENSG00000083093(gene)|ensembl:ENST00000261584(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001756"(somitogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007498"(mesoderm development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0048568"(embryonic organ development)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031920|interpro:IPR036322|interpro:IPR042417|mint:Q86YC2|rcsb pdb:2W18|rcsb pdb:3EU7|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|go:"GO:0001833"(inner cell mass cell proliferation)	-	-	-	figure legend:1A|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2014/02/06	2015/12/03	rogid:z3aviP3W7VXZGS7njC09B9M+fZs9606	rogid:/CusSIimN2s+1JZ83gI0GtaHdz09606	intact-crc:5DBBC3B55DBC8781|rigid:0fYMZEjW6YMt+64kqpcBJFabCW0	false	his tag:n-n|flag tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:O43502	uniprotkb:Q86YC2	intact:EBI-2267048|uniprotkb:Q3B783|uniprotkb:O43503|intact:EBI-28969664|ensembl:ENSP00000336701	intact:EBI-1222653|uniprotkb:Q8N7Y6|uniprotkb:Q8ND31|uniprotkb:Q9H6W1|uniprotkb:A6NIE1|ensembl:ENSP00000261584	psi-mi:ra51c_human(display_long)|uniprotkb:RAD51 homolog C(gene name synonym)|uniprotkb:RAD51C(gene name)|psi-mi:RAD51C(display_short)|uniprotkb:RAD51L2(gene name synonym)|uniprotkb:RAD51-like protein 2(gene name synonym)	psi-mi:palb2_human(display_long)|uniprotkb:PALB2(gene name)|psi-mi:PALB2(display_short)|uniprotkb:FANCN(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Park et al. (2013)	imex:IM-22188|pubmed:24141787	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9118886|imex:IM-22188-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000336701|ensembl:ENST00000421782|ensembl:ENSP00000391450|refseq:NP_002867.1|refseq:NP_478123.1|dip:DIP-41247N|ensembl:ENSG00000108384(gene)|ensembl:ENST00000337432(transcript)|go:"GO:0000707"(meiotic DNA recombinase assembly)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007066"(female meiosis sister chromatid cohesion)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030054"(cell junction)|go:"GO:0033063"(Rad51B-Rad51C-Rad51D-XRCC2 complex)|go:"GO:0033065"(Rad51C-XRCC3 complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|mint:O43502|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|reactome:R-HSA-983231	refseq:NP_078951.2|dip:DIP-38427N|ensembl:ENSG00000083093(gene)|ensembl:ENST00000261584(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001756"(somitogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007498"(mesoderm development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0048568"(embryonic organ development)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031920|interpro:IPR036322|interpro:IPR042417|mint:Q86YC2|rcsb pdb:2W18|rcsb pdb:3EU7|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|go:"GO:0001833"(inner cell mass cell proliferation)	-	-	-	figure legend:7|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/02/06	2015/12/03	rogid:z3aviP3W7VXZGS7njC09B9M+fZs9606	rogid:/CusSIimN2s+1JZ83gI0GtaHdz09606	intact-crc:DC5A8E8191A422C4|rigid:19NtrhBEdVRX6VYRuZNNpdKQByk	false	flag tag:n-n|mutation decreasing interaction:138-138|mutation decreasing interaction:258-258|mutation decreasing interaction:159-159|ha tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O43502	uniprotkb:P51587	intact:EBI-2267048|uniprotkb:Q3B783|uniprotkb:O43503|intact:EBI-28969664|ensembl:ENSP00000336701	intact:EBI-79792|ensembl:ENSP00000369497|ensembl:ENSP00000439902|uniprotkb:Q5TBJ7|uniprotkb:O00183|uniprotkb:O15008|uniprotkb:Q13879	psi-mi:ra51c_human(display_long)|uniprotkb:RAD51 homolog C(gene name synonym)|uniprotkb:RAD51C(gene name)|psi-mi:RAD51C(display_short)|uniprotkb:RAD51L2(gene name synonym)|uniprotkb:RAD51-like protein 2(gene name synonym)	psi-mi:brca2_human(display_long)|uniprotkb:BRCA2(gene name)|psi-mi:BRCA2(display_short)|uniprotkb:FANCD1(gene name synonym)|uniprotkb:FACD(gene name synonym)|uniprotkb:Fanconi anemia group D1 protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Park et al. (2013)	imex:IM-22188|pubmed:24141787	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9118886|imex:IM-22188-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000336701|ensembl:ENST00000421782|ensembl:ENSP00000391450|refseq:NP_002867.1|refseq:NP_478123.1|dip:DIP-41247N|ensembl:ENSG00000108384(gene)|ensembl:ENST00000337432(transcript)|go:"GO:0000707"(meiotic DNA recombinase assembly)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007066"(female meiosis sister chromatid cohesion)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030054"(cell junction)|go:"GO:0033063"(Rad51B-Rad51C-Rad51D-XRCC2 complex)|go:"GO:0033065"(Rad51C-XRCC3 complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|mint:O43502|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|reactome:R-HSA-983231	ensembl:ENSG00000139618(gene)|ensembl:ENST00000380152(transcript)|ensembl:ENST00000544455(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007569"(cell aging)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008585"(female gonad development)|go:"GO:0010165"(response to X-ray)|go:"GO:0010225"(response to UV-C)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030141"(secretory granule)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033593"(BRCA2-MAGE-D1 complex)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048478"(replication fork protection)|go:"GO:0051298"(centrosome duplication)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:1990426"(mitotic recombination-dependent replication fork processing)|interpro:IPR002093(BRCA2 repeat)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR015187(BRCA2, oligonucleotide/oligosaccharide-binding 1)|interpro:IPR015188(BRCA2, oligonucleotide/oligosaccharide-binding 3)|interpro:IPR015205(Tower)|interpro:IPR015252(BRCA2, helical)|interpro:IPR015525(Breast cancer type 2 susceptibility protein)|interpro:IPR036315|mint:P51587|rcsb pdb:1N0W|rcsb pdb:3EU7|rcsb pdb:6GY2|go:"GO:0007141"(male meiosis I)|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|rcsb pdb:6HQU|refseq:NP_000050.2|dip:DIP-24214N	-	-	-	figure legend:7|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/02/06	2015/12/03	rogid:z3aviP3W7VXZGS7njC09B9M+fZs9606	rogid:GvNlXMFXTHiRgOGT5EBlQUVh/+k9606	intact-crc:DC5A8E8191A422C4|rigid:19NtrhBEdVRX6VYRuZNNpdKQByk	false	flag tag:n-n|mutation decreasing interaction:138-138|mutation decreasing interaction:258-258|mutation decreasing interaction:159-159|ha tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q86YC2	uniprotkb:O43502	intact:EBI-1222653|uniprotkb:Q8N7Y6|uniprotkb:Q8ND31|uniprotkb:Q9H6W1|uniprotkb:A6NIE1|ensembl:ENSP00000261584	intact:EBI-2267048|uniprotkb:Q3B783|uniprotkb:O43503|intact:EBI-28969664|ensembl:ENSP00000336701	psi-mi:palb2_human(display_long)|uniprotkb:PALB2(gene name)|psi-mi:PALB2(display_short)|uniprotkb:FANCN(gene name synonym)	psi-mi:ra51c_human(display_long)|uniprotkb:RAD51 homolog C(gene name synonym)|uniprotkb:RAD51C(gene name)|psi-mi:RAD51C(display_short)|uniprotkb:RAD51L2(gene name synonym)|uniprotkb:RAD51-like protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Park et al. (2013)	imex:IM-22188|pubmed:24141787	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9211182|imex:IM-22188-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_078951.2|dip:DIP-38427N|ensembl:ENSG00000083093(gene)|ensembl:ENST00000261584(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001756"(somitogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007498"(mesoderm development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0048568"(embryonic organ development)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031920|interpro:IPR036322|interpro:IPR042417|mint:Q86YC2|rcsb pdb:2W18|rcsb pdb:3EU7|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|go:"GO:0001833"(inner cell mass cell proliferation)	ensembl:ENSP00000336701|ensembl:ENST00000421782|ensembl:ENSP00000391450|refseq:NP_002867.1|refseq:NP_478123.1|dip:DIP-41247N|ensembl:ENSG00000108384(gene)|ensembl:ENST00000337432(transcript)|go:"GO:0000707"(meiotic DNA recombinase assembly)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007066"(female meiosis sister chromatid cohesion)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030054"(cell junction)|go:"GO:0033063"(Rad51B-Rad51C-Rad51D-XRCC2 complex)|go:"GO:0033065"(Rad51C-XRCC3 complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|mint:O43502|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|reactome:R-HSA-983231	-	-	-	figure legend:6d|comment:"PALB2 mutant leu939trp did precipitate more BRCA2 and less RAD51C (same levels of RAD51)"|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-eufa1341)|taxid:9606(Homo sapiens)	-	2014/02/06	2015/12/03	rogid:/CusSIimN2s+1JZ83gI0GtaHdz09606	rogid:z3aviP3W7VXZGS7njC09B9M+fZs9606	intact-crc:5214B95A63B7F564|rigid:aGUgRn+HEEpIIUshIHSPnxYT7vY	false	flag tag:n-n|ha tag:n-n|mutation decreasing interaction:1143-1143	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q86YC2	uniprotkb:Q06609	intact:EBI-1222653|uniprotkb:Q8N7Y6|uniprotkb:Q8ND31|uniprotkb:Q9H6W1|uniprotkb:A6NIE1|ensembl:ENSP00000261584	intact:EBI-297202|uniprotkb:Q6FHX9|ensembl:ENSP00000267868|ensembl:ENSP00000433924|uniprotkb:B0FXP0|uniprotkb:Q9BV60|intact:EBI-1059207|uniprotkb:B2R8T6|uniprotkb:Q6ZNA8	psi-mi:palb2_human(display_long)|uniprotkb:PALB2(gene name)|psi-mi:PALB2(display_short)|uniprotkb:FANCN(gene name synonym)	psi-mi:rad51_human(display_long)|uniprotkb:RAD51(gene name)|psi-mi:RAD51(display_short)|uniprotkb:RAD51A(gene name synonym)|uniprotkb:RECA(gene name synonym)|uniprotkb:RAD51 homolog A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Park et al. (2013)	imex:IM-22188|pubmed:24141787	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9211182|imex:IM-22188-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_078951.2|dip:DIP-38427N|ensembl:ENSG00000083093(gene)|ensembl:ENST00000261584(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001756"(somitogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007498"(mesoderm development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0048568"(embryonic organ development)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031920|interpro:IPR036322|interpro:IPR042417|mint:Q86YC2|rcsb pdb:2W18|rcsb pdb:3EU7|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|go:"GO:0001833"(inner cell mass cell proliferation)	interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020587|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|mint:Q06609|rcsb pdb:1B22|rcsb pdb:1N0W|rcsb pdb:5H1B|rcsb pdb:5H1C|rcsb pdb:5JZC|rcsb pdb:5NP7|rcsb pdb:5NWL|rcsb pdb:7C9A|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|reactome:R-HSA-8953750|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0042148"(strand invasion)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051106"(positive regulation of DNA ligation)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0072719"(cellular response to cisplatin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072757"(cellular response to camptothecin)|go:"GO:1904631"(response to glucoside)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|go:"GO:1990426"(mitotic recombination-dependent replication fork processing)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010995(DNA repair Rad51/transcription factor NusA, alpha-helical)|interpro:IPR011941(DNA repair protein RAD51)|ensembl:ENSG00000051180(gene)|ensembl:ENST00000267868(transcript)|ensembl:ENST00000532743(transcript)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000800"(lateral element)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006312"(mitotic recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016605"(PML body)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0005815"(microtubule organizing center)|refseq:NP_001157742.1|refseq:NP_002866.2|refseq:NP_597994.3|refseq:XP_011520159.1|refseq:XP_011520160.1|refseq:XP_011520161.1|refseq:XP_011520162.1|refseq:XP_011520163.1|refseq:NP_001157741.1|refseq:XP_006720689.1|dip:DIP-462N	-	-	-	figure legend:6d|comment:"PALB2 mutant leu939trp did precipitate more BRCA2 and less RAD51C (same levels of RAD51)"|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-eufa1341)|taxid:9606(Homo sapiens)	-	2014/02/06	2015/12/03	rogid:/CusSIimN2s+1JZ83gI0GtaHdz09606	rogid:B7WPMU7tZuNcA2qjsTR+7i/OwFw9606	intact-crc:5214B95A63B7F564|rigid:aGUgRn+HEEpIIUshIHSPnxYT7vY	false	flag tag:n-n|ha tag:n-n|mutation decreasing interaction:1143-1143	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q86YC2	uniprotkb:P51587	intact:EBI-1222653|uniprotkb:Q8N7Y6|uniprotkb:Q8ND31|uniprotkb:Q9H6W1|uniprotkb:A6NIE1|ensembl:ENSP00000261584	intact:EBI-79792|ensembl:ENSP00000369497|ensembl:ENSP00000439902|uniprotkb:Q5TBJ7|uniprotkb:O00183|uniprotkb:O15008|uniprotkb:Q13879	psi-mi:palb2_human(display_long)|uniprotkb:PALB2(gene name)|psi-mi:PALB2(display_short)|uniprotkb:FANCN(gene name synonym)	psi-mi:brca2_human(display_long)|uniprotkb:BRCA2(gene name)|psi-mi:BRCA2(display_short)|uniprotkb:FANCD1(gene name synonym)|uniprotkb:FACD(gene name synonym)|uniprotkb:Fanconi anemia group D1 protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Park et al. (2013)	imex:IM-22188|pubmed:24141787	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9211182|imex:IM-22188-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_078951.2|dip:DIP-38427N|ensembl:ENSG00000083093(gene)|ensembl:ENST00000261584(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001756"(somitogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007498"(mesoderm development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0048568"(embryonic organ development)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031920|interpro:IPR036322|interpro:IPR042417|mint:Q86YC2|rcsb pdb:2W18|rcsb pdb:3EU7|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|go:"GO:0001833"(inner cell mass cell proliferation)	ensembl:ENSG00000139618(gene)|ensembl:ENST00000380152(transcript)|ensembl:ENST00000544455(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007569"(cell aging)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008585"(female gonad development)|go:"GO:0010165"(response to X-ray)|go:"GO:0010225"(response to UV-C)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030141"(secretory granule)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033593"(BRCA2-MAGE-D1 complex)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048478"(replication fork protection)|go:"GO:0051298"(centrosome duplication)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:1990426"(mitotic recombination-dependent replication fork processing)|interpro:IPR002093(BRCA2 repeat)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR015187(BRCA2, oligonucleotide/oligosaccharide-binding 1)|interpro:IPR015188(BRCA2, oligonucleotide/oligosaccharide-binding 3)|interpro:IPR015205(Tower)|interpro:IPR015252(BRCA2, helical)|interpro:IPR015525(Breast cancer type 2 susceptibility protein)|interpro:IPR036315|mint:P51587|rcsb pdb:1N0W|rcsb pdb:3EU7|rcsb pdb:6GY2|go:"GO:0007141"(male meiosis I)|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|rcsb pdb:6HQU|refseq:NP_000050.2|dip:DIP-24214N	-	-	-	figure legend:6d|comment:"PALB2 mutant leu939trp did precipitate more BRCA2 and less RAD51C (same levels of RAD51)"|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-eufa1341)|taxid:9606(Homo sapiens)	-	2014/02/06	2015/12/03	rogid:/CusSIimN2s+1JZ83gI0GtaHdz09606	rogid:GvNlXMFXTHiRgOGT5EBlQUVh/+k9606	intact-crc:5214B95A63B7F564|rigid:aGUgRn+HEEpIIUshIHSPnxYT7vY	false	flag tag:n-n|ha tag:n-n|mutation decreasing interaction:1143-1143	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q86YC2	uniprotkb:O43502	intact:EBI-1222653|uniprotkb:Q8N7Y6|uniprotkb:Q8ND31|uniprotkb:Q9H6W1|uniprotkb:A6NIE1|ensembl:ENSP00000261584	intact:EBI-2267048|uniprotkb:Q3B783|uniprotkb:O43503|intact:EBI-28969664|ensembl:ENSP00000336701	psi-mi:palb2_human(display_long)|uniprotkb:PALB2(gene name)|psi-mi:PALB2(display_short)|uniprotkb:FANCN(gene name synonym)	psi-mi:ra51c_human(display_long)|uniprotkb:RAD51 homolog C(gene name synonym)|uniprotkb:RAD51C(gene name)|psi-mi:RAD51C(display_short)|uniprotkb:RAD51L2(gene name synonym)|uniprotkb:RAD51-like protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Park et al. (2013)	imex:IM-22188|pubmed:24141787	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9350269|imex:IM-22188-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_078951.2|dip:DIP-38427N|ensembl:ENSG00000083093(gene)|ensembl:ENST00000261584(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001756"(somitogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007498"(mesoderm development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0048568"(embryonic organ development)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031920|interpro:IPR036322|interpro:IPR042417|mint:Q86YC2|rcsb pdb:2W18|rcsb pdb:3EU7|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|go:"GO:0001833"(inner cell mass cell proliferation)	ensembl:ENSP00000336701|ensembl:ENST00000421782|ensembl:ENSP00000391450|refseq:NP_002867.1|refseq:NP_478123.1|dip:DIP-41247N|ensembl:ENSG00000108384(gene)|ensembl:ENST00000337432(transcript)|go:"GO:0000707"(meiotic DNA recombinase assembly)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007066"(female meiosis sister chromatid cohesion)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030054"(cell junction)|go:"GO:0033063"(Rad51B-Rad51C-Rad51D-XRCC2 complex)|go:"GO:0033065"(Rad51C-XRCC3 complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|mint:O43502|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|reactome:R-HSA-983231	-	-	-	figure legend:2C|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-eufa1341)|taxid:9606(Homo sapiens)	-	2014/02/06	2015/12/03	rogid:/CusSIimN2s+1JZ83gI0GtaHdz09606	rogid:z3aviP3W7VXZGS7njC09B9M+fZs9606	intact-crc:04CB3BC0F53C0A63|rigid:aGUgRn+HEEpIIUshIHSPnxYT7vY	false	necessary binding region:1098-1186|his tag:n-n|flag tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q86YC2	uniprotkb:P51587	intact:EBI-1222653|uniprotkb:Q8N7Y6|uniprotkb:Q8ND31|uniprotkb:Q9H6W1|uniprotkb:A6NIE1|ensembl:ENSP00000261584	intact:EBI-79792|ensembl:ENSP00000369497|ensembl:ENSP00000439902|uniprotkb:Q5TBJ7|uniprotkb:O00183|uniprotkb:O15008|uniprotkb:Q13879	psi-mi:palb2_human(display_long)|uniprotkb:PALB2(gene name)|psi-mi:PALB2(display_short)|uniprotkb:FANCN(gene name synonym)	psi-mi:brca2_human(display_long)|uniprotkb:BRCA2(gene name)|psi-mi:BRCA2(display_short)|uniprotkb:FANCD1(gene name synonym)|uniprotkb:FACD(gene name synonym)|uniprotkb:Fanconi anemia group D1 protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Park et al. (2013)	imex:IM-22188|pubmed:24141787	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9350269|imex:IM-22188-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_078951.2|dip:DIP-38427N|ensembl:ENSG00000083093(gene)|ensembl:ENST00000261584(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001756"(somitogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007498"(mesoderm development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0048568"(embryonic organ development)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031920|interpro:IPR036322|interpro:IPR042417|mint:Q86YC2|rcsb pdb:2W18|rcsb pdb:3EU7|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|go:"GO:0001833"(inner cell mass cell proliferation)	ensembl:ENSG00000139618(gene)|ensembl:ENST00000380152(transcript)|ensembl:ENST00000544455(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007569"(cell aging)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008585"(female gonad development)|go:"GO:0010165"(response to X-ray)|go:"GO:0010225"(response to UV-C)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030141"(secretory granule)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033593"(BRCA2-MAGE-D1 complex)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048478"(replication fork protection)|go:"GO:0051298"(centrosome duplication)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:1990426"(mitotic recombination-dependent replication fork processing)|interpro:IPR002093(BRCA2 repeat)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR015187(BRCA2, oligonucleotide/oligosaccharide-binding 1)|interpro:IPR015188(BRCA2, oligonucleotide/oligosaccharide-binding 3)|interpro:IPR015205(Tower)|interpro:IPR015252(BRCA2, helical)|interpro:IPR015525(Breast cancer type 2 susceptibility protein)|interpro:IPR036315|mint:P51587|rcsb pdb:1N0W|rcsb pdb:3EU7|rcsb pdb:6GY2|go:"GO:0007141"(male meiosis I)|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|rcsb pdb:6HQU|refseq:NP_000050.2|dip:DIP-24214N	-	-	-	figure legend:2C|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-eufa1341)|taxid:9606(Homo sapiens)	-	2014/02/06	2015/12/03	rogid:/CusSIimN2s+1JZ83gI0GtaHdz09606	rogid:GvNlXMFXTHiRgOGT5EBlQUVh/+k9606	intact-crc:04CB3BC0F53C0A63|rigid:aGUgRn+HEEpIIUshIHSPnxYT7vY	false	necessary binding region:1098-1186|his tag:n-n|flag tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q86YC2	uniprotkb:Q06609	intact:EBI-1222653|uniprotkb:Q8N7Y6|uniprotkb:Q8ND31|uniprotkb:Q9H6W1|uniprotkb:A6NIE1|ensembl:ENSP00000261584	intact:EBI-297202|uniprotkb:Q6FHX9|ensembl:ENSP00000267868|ensembl:ENSP00000433924|uniprotkb:B0FXP0|uniprotkb:Q9BV60|intact:EBI-1059207|uniprotkb:B2R8T6|uniprotkb:Q6ZNA8	psi-mi:palb2_human(display_long)|uniprotkb:PALB2(gene name)|psi-mi:PALB2(display_short)|uniprotkb:FANCN(gene name synonym)	psi-mi:rad51_human(display_long)|uniprotkb:RAD51(gene name)|psi-mi:RAD51(display_short)|uniprotkb:RAD51A(gene name synonym)|uniprotkb:RECA(gene name synonym)|uniprotkb:RAD51 homolog A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Park et al. (2013)	imex:IM-22188|pubmed:24141787	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9350269|imex:IM-22188-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_078951.2|dip:DIP-38427N|ensembl:ENSG00000083093(gene)|ensembl:ENST00000261584(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001756"(somitogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007498"(mesoderm development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0048568"(embryonic organ development)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031920|interpro:IPR036322|interpro:IPR042417|mint:Q86YC2|rcsb pdb:2W18|rcsb pdb:3EU7|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|go:"GO:0001833"(inner cell mass cell proliferation)	interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020587|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|mint:Q06609|rcsb pdb:1B22|rcsb pdb:1N0W|rcsb pdb:5H1B|rcsb pdb:5H1C|rcsb pdb:5JZC|rcsb pdb:5NP7|rcsb pdb:5NWL|rcsb pdb:7C9A|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|reactome:R-HSA-8953750|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0042148"(strand invasion)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051106"(positive regulation of DNA ligation)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0072719"(cellular response to cisplatin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072757"(cellular response to camptothecin)|go:"GO:1904631"(response to glucoside)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|go:"GO:1990426"(mitotic recombination-dependent replication fork processing)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010995(DNA repair Rad51/transcription factor NusA, alpha-helical)|interpro:IPR011941(DNA repair protein RAD51)|ensembl:ENSG00000051180(gene)|ensembl:ENST00000267868(transcript)|ensembl:ENST00000532743(transcript)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000800"(lateral element)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006312"(mitotic recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016605"(PML body)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0005815"(microtubule organizing center)|refseq:NP_001157742.1|refseq:NP_002866.2|refseq:NP_597994.3|refseq:XP_011520159.1|refseq:XP_011520160.1|refseq:XP_011520161.1|refseq:XP_011520162.1|refseq:XP_011520163.1|refseq:NP_001157741.1|refseq:XP_006720689.1|dip:DIP-462N	-	-	-	figure legend:2C|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-eufa1341)|taxid:9606(Homo sapiens)	-	2014/02/06	2015/12/03	rogid:/CusSIimN2s+1JZ83gI0GtaHdz09606	rogid:B7WPMU7tZuNcA2qjsTR+7i/OwFw9606	intact-crc:04CB3BC0F53C0A63|rigid:aGUgRn+HEEpIIUshIHSPnxYT7vY	false	necessary binding region:1098-1186|his tag:n-n|flag tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q86YC2	uniprotkb:O43502	intact:EBI-1222653|uniprotkb:Q8N7Y6|uniprotkb:Q8ND31|uniprotkb:Q9H6W1|uniprotkb:A6NIE1|ensembl:ENSP00000261584	intact:EBI-2267048|uniprotkb:Q3B783|uniprotkb:O43503|intact:EBI-28969664|ensembl:ENSP00000336701	psi-mi:palb2_human(display_long)|uniprotkb:PALB2(gene name)|psi-mi:PALB2(display_short)|uniprotkb:FANCN(gene name synonym)	psi-mi:ra51c_human(display_long)|uniprotkb:RAD51 homolog C(gene name synonym)|uniprotkb:RAD51C(gene name)|psi-mi:RAD51C(display_short)|uniprotkb:RAD51L2(gene name synonym)|uniprotkb:RAD51-like protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Park et al. (2013)	imex:IM-22188|pubmed:24141787	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9118478|imex:IM-22188-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_078951.2|dip:DIP-38427N|ensembl:ENSG00000083093(gene)|ensembl:ENST00000261584(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001756"(somitogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007498"(mesoderm development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0048568"(embryonic organ development)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031920|interpro:IPR036322|interpro:IPR042417|mint:Q86YC2|rcsb pdb:2W18|rcsb pdb:3EU7|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|go:"GO:0001833"(inner cell mass cell proliferation)	ensembl:ENSP00000336701|ensembl:ENST00000421782|ensembl:ENSP00000391450|refseq:NP_002867.1|refseq:NP_478123.1|dip:DIP-41247N|ensembl:ENSG00000108384(gene)|ensembl:ENST00000337432(transcript)|go:"GO:0000707"(meiotic DNA recombinase assembly)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007066"(female meiosis sister chromatid cohesion)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030054"(cell junction)|go:"GO:0033063"(Rad51B-Rad51C-Rad51D-XRCC2 complex)|go:"GO:0033065"(Rad51C-XRCC3 complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|mint:O43502|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|reactome:R-HSA-983231	-	-	-	figure legend:1C|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-eufa1341)|taxid:9606(Homo sapiens)	-	2014/02/06	2015/12/03	rogid:/CusSIimN2s+1JZ83gI0GtaHdz09606	rogid:z3aviP3W7VXZGS7njC09B9M+fZs9606	intact-crc:3C8C82A4ACAF5B55|rigid:sr0xpEAg16hEZ5USNQ6Gd6psuVw	false	his tag:n-n|flag tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q86YC2	uniprotkb:P51587	intact:EBI-1222653|uniprotkb:Q8N7Y6|uniprotkb:Q8ND31|uniprotkb:Q9H6W1|uniprotkb:A6NIE1|ensembl:ENSP00000261584	intact:EBI-79792|ensembl:ENSP00000369497|ensembl:ENSP00000439902|uniprotkb:Q5TBJ7|uniprotkb:O00183|uniprotkb:O15008|uniprotkb:Q13879	psi-mi:palb2_human(display_long)|uniprotkb:PALB2(gene name)|psi-mi:PALB2(display_short)|uniprotkb:FANCN(gene name synonym)	psi-mi:brca2_human(display_long)|uniprotkb:BRCA2(gene name)|psi-mi:BRCA2(display_short)|uniprotkb:FANCD1(gene name synonym)|uniprotkb:FACD(gene name synonym)|uniprotkb:Fanconi anemia group D1 protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Park et al. (2013)	imex:IM-22188|pubmed:24141787	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9118478|imex:IM-22188-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_078951.2|dip:DIP-38427N|ensembl:ENSG00000083093(gene)|ensembl:ENST00000261584(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001756"(somitogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007498"(mesoderm development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0048568"(embryonic organ development)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031920|interpro:IPR036322|interpro:IPR042417|mint:Q86YC2|rcsb pdb:2W18|rcsb pdb:3EU7|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|go:"GO:0001833"(inner cell mass cell proliferation)	ensembl:ENSG00000139618(gene)|ensembl:ENST00000380152(transcript)|ensembl:ENST00000544455(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007569"(cell aging)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008585"(female gonad development)|go:"GO:0010165"(response to X-ray)|go:"GO:0010225"(response to UV-C)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030141"(secretory granule)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033593"(BRCA2-MAGE-D1 complex)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048478"(replication fork protection)|go:"GO:0051298"(centrosome duplication)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:1990426"(mitotic recombination-dependent replication fork processing)|interpro:IPR002093(BRCA2 repeat)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR015187(BRCA2, oligonucleotide/oligosaccharide-binding 1)|interpro:IPR015188(BRCA2, oligonucleotide/oligosaccharide-binding 3)|interpro:IPR015205(Tower)|interpro:IPR015252(BRCA2, helical)|interpro:IPR015525(Breast cancer type 2 susceptibility protein)|interpro:IPR036315|mint:P51587|rcsb pdb:1N0W|rcsb pdb:3EU7|rcsb pdb:6GY2|go:"GO:0007141"(male meiosis I)|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|rcsb pdb:6HQU|refseq:NP_000050.2|dip:DIP-24214N	-	-	-	figure legend:1C|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-eufa1341)|taxid:9606(Homo sapiens)	-	2014/02/06	2015/12/03	rogid:/CusSIimN2s+1JZ83gI0GtaHdz09606	rogid:GvNlXMFXTHiRgOGT5EBlQUVh/+k9606	intact-crc:3C8C82A4ACAF5B55|rigid:sr0xpEAg16hEZ5USNQ6Gd6psuVw	false	his tag:n-n|flag tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q86YC2	uniprotkb:O43542	intact:EBI-1222653|uniprotkb:Q8N7Y6|uniprotkb:Q8ND31|uniprotkb:Q9H6W1|uniprotkb:A6NIE1|ensembl:ENSP00000261584	intact:EBI-2849976|uniprotkb:Q9BU18|uniprotkb:O43568|ensembl:ENSP00000343392|ensembl:ENSP00000451362|ensembl:ENSP00000451974|ensembl:ENSP00000452598	psi-mi:palb2_human(display_long)|uniprotkb:PALB2(gene name)|psi-mi:PALB2(display_short)|uniprotkb:FANCN(gene name synonym)	psi-mi:xrcc3_human(display_long)|uniprotkb:XRCC3(gene name)|psi-mi:XRCC3(display_short)|uniprotkb:X-ray repair cross-complementing protein 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Park et al. (2013)	imex:IM-22188|pubmed:24141787	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9118478|imex:IM-22188-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_078951.2|dip:DIP-38427N|ensembl:ENSG00000083093(gene)|ensembl:ENST00000261584(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001756"(somitogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007498"(mesoderm development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0048568"(embryonic organ development)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031920|interpro:IPR036322|interpro:IPR042417|mint:Q86YC2|rcsb pdb:2W18|rcsb pdb:3EU7|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|go:"GO:0001833"(inner cell mass cell proliferation)	refseq:XP_011535440.1|refseq:NP_001093588.1|refseq:NP_001093589.1|refseq:NP_005423.1|refseq:XP_005268103.1|dip:DIP-42016N|ensembl:ENSG00000126215(gene)|ensembl:ENST00000352127(transcript)|ensembl:ENST00000553264(transcript)|ensembl:ENST00000554913(transcript)|ensembl:ENST00000555055(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0010033"(response to organic substance)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0033065"(Rad51C-XRCC3 complex)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0045003"(double-strand break repair via synthesis-dependent strand annealing)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071140"(resolution of mitotic recombination intermediates)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:0090656"(t-circle formation)|go:"GO:0090657"(telomeric loop disassembly)|go:"GO:0090737"(telomere maintenance via telomere trimming)|interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|go:"GO:0005524"(ATP binding)	-	-	-	figure legend:1C|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-eufa1341)|taxid:9606(Homo sapiens)	-	2014/02/06	2015/12/03	rogid:/CusSIimN2s+1JZ83gI0GtaHdz09606	rogid:3vDLDeKRnmV6Wg9dK2yMbIRqzVk9606	intact-crc:3C8C82A4ACAF5B55|rigid:sr0xpEAg16hEZ5USNQ6Gd6psuVw	false	his tag:n-n|flag tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O43502	uniprotkb:Q86YC2	intact:EBI-2267048|uniprotkb:Q3B783|uniprotkb:O43503|intact:EBI-28969664|ensembl:ENSP00000336701	intact:EBI-1222653|uniprotkb:Q8N7Y6|uniprotkb:Q8ND31|uniprotkb:Q9H6W1|uniprotkb:A6NIE1|ensembl:ENSP00000261584	psi-mi:ra51c_human(display_long)|uniprotkb:RAD51 homolog C(gene name synonym)|uniprotkb:RAD51C(gene name)|psi-mi:RAD51C(display_short)|uniprotkb:RAD51L2(gene name synonym)|uniprotkb:RAD51-like protein 2(gene name synonym)	psi-mi:palb2_human(display_long)|uniprotkb:PALB2(gene name)|psi-mi:PALB2(display_short)|uniprotkb:FANCN(gene name synonym)	psi-mi:"MI:0096"(pull down)	Park et al. (2013)	imex:IM-22188|pubmed:24141787	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9118625|imex:IM-22188-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000336701|ensembl:ENST00000421782|ensembl:ENSP00000391450|refseq:NP_002867.1|refseq:NP_478123.1|dip:DIP-41247N|ensembl:ENSG00000108384(gene)|ensembl:ENST00000337432(transcript)|go:"GO:0000707"(meiotic DNA recombinase assembly)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007066"(female meiosis sister chromatid cohesion)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030054"(cell junction)|go:"GO:0033063"(Rad51B-Rad51C-Rad51D-XRCC2 complex)|go:"GO:0033065"(Rad51C-XRCC3 complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|mint:O43502|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|reactome:R-HSA-983231	refseq:NP_078951.2|dip:DIP-38427N|ensembl:ENSG00000083093(gene)|ensembl:ENST00000261584(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001756"(somitogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007498"(mesoderm development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0048568"(embryonic organ development)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031920|interpro:IPR036322|interpro:IPR042417|mint:Q86YC2|rcsb pdb:2W18|rcsb pdb:3EU7|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|go:"GO:0001833"(inner cell mass cell proliferation)	-	-	-	figure legend:2D and 4a and b|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/02/06	2014/10/16	rogid:z3aviP3W7VXZGS7njC09B9M+fZs9606	rogid:/CusSIimN2s+1JZ83gI0GtaHdz09606	intact-crc:2BB254B93988196A|rigid:n4aGGy3uII75LpinuuDHv3oGOHU	false	his tag:c-c	sufficient binding region:859-1186(IPR015943)|mutation decreasing interaction:1030-1030|mutation decreasing interaction:1143-1143|maltose binding protein tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q06609	uniprotkb:Q86YC2	intact:EBI-297202|uniprotkb:Q6FHX9|ensembl:ENSP00000267868|ensembl:ENSP00000433924|uniprotkb:B0FXP0|uniprotkb:Q9BV60|intact:EBI-1059207|uniprotkb:B2R8T6|uniprotkb:Q6ZNA8	intact:EBI-1222653|uniprotkb:Q8N7Y6|uniprotkb:Q8ND31|uniprotkb:Q9H6W1|uniprotkb:A6NIE1|ensembl:ENSP00000261584	psi-mi:rad51_human(display_long)|uniprotkb:RAD51(gene name)|psi-mi:RAD51(display_short)|uniprotkb:RAD51A(gene name synonym)|uniprotkb:RECA(gene name synonym)|uniprotkb:RAD51 homolog A(gene name synonym)	psi-mi:palb2_human(display_long)|uniprotkb:PALB2(gene name)|psi-mi:PALB2(display_short)|uniprotkb:FANCN(gene name synonym)	psi-mi:"MI:0096"(pull down)	Park et al. (2013)	imex:IM-22188|pubmed:24141787	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9118852|imex:IM-22188-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020587|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|mint:Q06609|rcsb pdb:1B22|rcsb pdb:1N0W|rcsb pdb:5H1B|rcsb pdb:5H1C|rcsb pdb:5JZC|rcsb pdb:5NP7|rcsb pdb:5NWL|rcsb pdb:7C9A|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|reactome:R-HSA-8953750|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0042148"(strand invasion)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051106"(positive regulation of DNA ligation)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0072719"(cellular response to cisplatin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072757"(cellular response to camptothecin)|go:"GO:1904631"(response to glucoside)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|go:"GO:1990426"(mitotic recombination-dependent replication fork processing)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010995(DNA repair Rad51/transcription factor NusA, alpha-helical)|interpro:IPR011941(DNA repair protein RAD51)|ensembl:ENSG00000051180(gene)|ensembl:ENST00000267868(transcript)|ensembl:ENST00000532743(transcript)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000800"(lateral element)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006312"(mitotic recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016605"(PML body)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0005815"(microtubule organizing center)|refseq:NP_001157742.1|refseq:NP_002866.2|refseq:NP_597994.3|refseq:XP_011520159.1|refseq:XP_011520160.1|refseq:XP_011520161.1|refseq:XP_011520162.1|refseq:XP_011520163.1|refseq:NP_001157741.1|refseq:XP_006720689.1|dip:DIP-462N	refseq:NP_078951.2|dip:DIP-38427N|ensembl:ENSG00000083093(gene)|ensembl:ENST00000261584(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001756"(somitogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007498"(mesoderm development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0048568"(embryonic organ development)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031920|interpro:IPR036322|interpro:IPR042417|mint:Q86YC2|rcsb pdb:2W18|rcsb pdb:3EU7|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|go:"GO:0001833"(inner cell mass cell proliferation)	-	-	-	figure legend:4a and b|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/02/06	2014/10/16	rogid:B7WPMU7tZuNcA2qjsTR+7i/OwFw9606	rogid:/CusSIimN2s+1JZ83gI0GtaHdz09606	intact-crc:E7B90FAD8F89D019|rigid:JlK02iWUT9MB1nSR63QFussaBUQ	false	his tag:?-?	sufficient binding region:859-1186(IPR015943)|mutation decreasing interaction:939-939|mutation decreasing interaction:1143-1143|maltose binding protein tag:n-n|mutation decreasing interaction:1030-1030	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q86YC2	uniprotkb:P51587	intact:EBI-1222653|uniprotkb:Q8N7Y6|uniprotkb:Q8ND31|uniprotkb:Q9H6W1|uniprotkb:A6NIE1|ensembl:ENSP00000261584	intact:EBI-79792|ensembl:ENSP00000369497|ensembl:ENSP00000439902|uniprotkb:Q5TBJ7|uniprotkb:O00183|uniprotkb:O15008|uniprotkb:Q13879	psi-mi:palb2_human(display_long)|uniprotkb:PALB2(gene name)|psi-mi:PALB2(display_short)|uniprotkb:FANCN(gene name synonym)	psi-mi:brca2_human(display_long)|uniprotkb:BRCA2(gene name)|psi-mi:BRCA2(display_short)|uniprotkb:FANCD1(gene name synonym)|uniprotkb:FACD(gene name synonym)|uniprotkb:Fanconi anemia group D1 protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Park et al. (2013)	imex:IM-22188|pubmed:24141787	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9118793|imex:IM-22188-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_078951.2|dip:DIP-38427N|ensembl:ENSG00000083093(gene)|ensembl:ENST00000261584(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001756"(somitogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007498"(mesoderm development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0048568"(embryonic organ development)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031920|interpro:IPR036322|interpro:IPR042417|mint:Q86YC2|rcsb pdb:2W18|rcsb pdb:3EU7|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|go:"GO:0001833"(inner cell mass cell proliferation)	ensembl:ENSG00000139618(gene)|ensembl:ENST00000380152(transcript)|ensembl:ENST00000544455(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007569"(cell aging)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008585"(female gonad development)|go:"GO:0010165"(response to X-ray)|go:"GO:0010225"(response to UV-C)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030141"(secretory granule)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033593"(BRCA2-MAGE-D1 complex)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048478"(replication fork protection)|go:"GO:0051298"(centrosome duplication)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:1990426"(mitotic recombination-dependent replication fork processing)|interpro:IPR002093(BRCA2 repeat)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR015187(BRCA2, oligonucleotide/oligosaccharide-binding 1)|interpro:IPR015188(BRCA2, oligonucleotide/oligosaccharide-binding 3)|interpro:IPR015205(Tower)|interpro:IPR015252(BRCA2, helical)|interpro:IPR015525(Breast cancer type 2 susceptibility protein)|interpro:IPR036315|mint:P51587|rcsb pdb:1N0W|rcsb pdb:3EU7|rcsb pdb:6GY2|go:"GO:0007141"(male meiosis I)|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|rcsb pdb:6HQU|refseq:NP_000050.2|dip:DIP-24214N	-	-	-	figure legend:4a and b|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/02/06	2015/12/03	rogid:/CusSIimN2s+1JZ83gI0GtaHdz09606	rogid:GvNlXMFXTHiRgOGT5EBlQUVh/+k9606	intact-crc:814BBB1DC72E54CF|rigid:aEVew4dPMTS+yjbvdTAkm5Nxnss	false	mutation decreasing interaction:939-939|sufficient binding region:859-1186(IPR015943)|maltose binding protein tag:n-n|mutation decreasing interaction:1143-1143	sufficient binding region:1-75|glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q86YC2	uniprotkb:O43542	intact:EBI-1222653|uniprotkb:Q8N7Y6|uniprotkb:Q8ND31|uniprotkb:Q9H6W1|uniprotkb:A6NIE1|ensembl:ENSP00000261584	intact:EBI-2849976|uniprotkb:Q9BU18|uniprotkb:O43568|ensembl:ENSP00000343392|ensembl:ENSP00000451362|ensembl:ENSP00000451974|ensembl:ENSP00000452598	psi-mi:palb2_human(display_long)|uniprotkb:PALB2(gene name)|psi-mi:PALB2(display_short)|uniprotkb:FANCN(gene name synonym)	psi-mi:xrcc3_human(display_long)|uniprotkb:XRCC3(gene name)|psi-mi:XRCC3(display_short)|uniprotkb:X-ray repair cross-complementing protein 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Park et al. (2013)	imex:IM-22188|pubmed:24141787	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9118832|imex:IM-22188-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_078951.2|dip:DIP-38427N|ensembl:ENSG00000083093(gene)|ensembl:ENST00000261584(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001756"(somitogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007498"(mesoderm development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0048568"(embryonic organ development)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031920|interpro:IPR036322|interpro:IPR042417|mint:Q86YC2|rcsb pdb:2W18|rcsb pdb:3EU7|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|go:"GO:0001833"(inner cell mass cell proliferation)	refseq:XP_011535440.1|refseq:NP_001093588.1|refseq:NP_001093589.1|refseq:NP_005423.1|refseq:XP_005268103.1|dip:DIP-42016N|ensembl:ENSG00000126215(gene)|ensembl:ENST00000352127(transcript)|ensembl:ENST00000553264(transcript)|ensembl:ENST00000554913(transcript)|ensembl:ENST00000555055(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0010033"(response to organic substance)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0033065"(Rad51C-XRCC3 complex)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0045003"(double-strand break repair via synthesis-dependent strand annealing)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071140"(resolution of mitotic recombination intermediates)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:0090656"(t-circle formation)|go:"GO:0090657"(telomeric loop disassembly)|go:"GO:0090737"(telomere maintenance via telomere trimming)|interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|go:"GO:0005524"(ATP binding)	-	-	-	figure legend:4a and b|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/02/06	2014/10/16	rogid:/CusSIimN2s+1JZ83gI0GtaHdz09606	rogid:3vDLDeKRnmV6Wg9dK2yMbIRqzVk9606	intact-crc:C3CB47853E19B5C5|rigid:JUFE1Tab2TypIushobOrO2JI0q4	false	sufficient binding region:859-1186(IPR015943)|mutation decreasing interaction:939-939|mutation decreasing interaction:1143-1143|maltose binding protein tag:n-n	his tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)