#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:E9Q9K5	uniprotkb:P23327	intact:EBI-9639740|uniprotkb:Q8VIN7|uniprotkb:Q8VIN8|uniprotkb:Q8VIN9|uniprotkb:Q9CV36|ensembl:ENSMUSP00000093436	intact:EBI-9639760|uniprotkb:Q504Y6|ensembl:ENSP00000252825	psi-mi:trdn_mouse(display_long)|uniprotkb:Trdn(gene name)|psi-mi:Trdn(display_short)	psi-mi:srch_human(display_long)|uniprotkb:HRC(gene name)|psi-mi:HRC(display_short)|uniprotkb:HCP(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Singh et al. (2013)	pubmed:24125847|imex:IM-22948	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-9639739|imex:IM-22948-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_084002.2|ensembl:ENSMUSG00000019787(gene)|ensembl:ENSMUST00000095762(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0009617"(response to bacterium)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014701"(junctional sarcoplasmic reticulum membrane)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030314"(junctional membrane complex)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0034704"(calcium channel complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051280"(negative regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0060047"(heart contraction)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0086036"(regulation of cardiac muscle cell membrane potential)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR010798(Triadin)|reactome:R-MMU-2672351|reactome:R-MMU-5578775	refseq:NP_002143.1|ensembl:ENSG00000130528(gene)|ensembl:ENST00000252825(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006936"(muscle contraction)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0030018"(Z disc)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0033135"(regulation of peptidyl-serine phosphorylation)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0051117"(ATPase binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|go:"GO:1901899"(positive regulation of relaxation of cardiac muscle)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|interpro:IPR015666(Histidine-rich calcium-binding protein)|interpro:IPR019552|reactome:R-HSA-381426|reactome:R-HSA-8957275	-	-	-	comment:cardiac homogenate|figure legend:Fig 6A and B|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2014/07/10	2014/10/16	rogid:FUnhabghR4SUMI550kE/N9td8nI10090	rogid:0MaUpv/EsS+BOJ7Nv3HAtl6T/yQ9606	intact-crc:66445A401FF452B0|rigid:ikGITn94g6OR01oAfXtWMShCJpY	false	-	mutation decreasing interaction:96-96	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:Q28820	uniprotkb:P23327	intact:EBI-8060615|uniprotkb:Q28637|uniprotkb:Q28636|intact:MINT-224232|uniprotkb:Q28643	intact:EBI-9639760|uniprotkb:Q504Y6|ensembl:ENSP00000252825	psi-mi:trdn_rabit(display_long)|uniprotkb:TRDN(gene name)|psi-mi:TRDN(display_short)	psi-mi:srch_human(display_long)|uniprotkb:HRC(gene name)|psi-mi:HRC(display_short)|uniprotkb:HCP(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Singh et al. (2013)	pubmed:24125847|imex:IM-22948	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-9639791|imex:IM-22948-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001076212.1|go:"GO:0005102"(signaling receptor binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|interpro:IPR010798(Triadin)	refseq:NP_002143.1|ensembl:ENSG00000130528(gene)|ensembl:ENST00000252825(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006936"(muscle contraction)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0030018"(Z disc)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0033135"(regulation of peptidyl-serine phosphorylation)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0051117"(ATPase binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|go:"GO:1901899"(positive regulation of relaxation of cardiac muscle)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|interpro:IPR015666(Histidine-rich calcium-binding protein)|interpro:IPR019552|reactome:R-HSA-381426|reactome:R-HSA-8957275	-	comment:mint|function:May be involved in anchoring calsequestrin to the junctional sarcoplasmic reticulum and allowing its functional coupling with the ryanodine receptor	-	figure legend:Fig 6C and D|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2014/07/10	2014/10/16	rogid:gxTCeFZeuXwtVjW8kcC4WdIHa9s9986	rogid:0MaUpv/EsS+BOJ7Nv3HAtl6T/yQ9606	intact-crc:EE053CAD827364D5|rigid:azUzpN1lXPT3nSDBrL+MjR1f7i4	false	green fluorescent protein tag:?-?	mutation decreasing interaction:96-96|green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)