#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q99962	uniprotkb:Q70E73	intact:EBI-77938|ensembl:ENSP00000369981|uniprotkb:Q9NQK5|uniprotkb:B2R618	intact:EBI-3940924|uniprotkb:Q9C0I2|uniprotkb:Q96Q37|ensembl:ENSP00000316543	psi-mi:sh3g2_human(display_long)|uniprotkb:SH3GL2(gene name)|psi-mi:SH3GL2(display_short)|uniprotkb:CNSA2(gene name synonym)|uniprotkb:SH3D2A(gene name synonym)|uniprotkb:Endophilin-1(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 2(gene name synonym)|uniprotkb:SH3 domain protein 2A(gene name synonym)|uniprotkb:EEN-B1(gene name synonym)	psi-mi:raph1_human(display_long)|uniprotkb:RAPH1(gene name)|psi-mi:RAPH1(display_short)|uniprotkb:ALS2CR18(gene name synonym)|uniprotkb:ALS2CR9(gene name synonym)|uniprotkb:KIAA1681(gene name synonym)|uniprotkb:LPD(gene name synonym)|uniprotkb:PREL2(gene name synonym)|uniprotkb:RMO1(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 18 protein(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 9 protein(gene name synonym)|uniprotkb:Lamellipodin(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 2(gene name synonym)|uniprotkb:Protein RMO1(gene name synonym)	psi-mi:"MI:0089"(protein array)	Vehlow et al. (2013)	imex:IM-22206|pubmed:24076656	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9119125|imex:IM-22206-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0097749"(membrane tubulation)|go:"GO:0097753"(membrane bending)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099050"(vesicle scission)|go:"GO:1903527"(positive regulation of membrane tubulation)|go:"GO:1905604"(negative regulation of blood-brain barrier permeability)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:2000369"(regulation of clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035824|interpro:IPR036028|mint:Q99962|rcsb pdb:1X03|rcsb pdb:1X04|rcsb pdb:2D4C|rcsb pdb:2DBM|reactome:R-HSA-177504|reactome:R-HSA-182971|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|ensembl:ENSG00000107295(gene)|ensembl:ENST00000380607(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0097441"(basal dendrite)|go:"GO:0097484"(dendrite extension)|refseq:NP_003017.1|dip:DIP-30996N	refseq:NP_976241.1|refseq:NP_998754.1|ensembl:ENST00000308091|ensembl:ENSP00000311293|ensembl:ENSP00000316543|ensembl:ENST00000418114|ensembl:ENSP00000396711|ensembl:ENST00000419464|ensembl:ENSP00000390578|ensembl:ENST00000423104|ensembl:ENSP00000397751|ensembl:ENST00000439222|ensembl:ENSP00000411138|ensembl:ENST00000453034|ensembl:ENSP00000406662|dip:DIP-61336N|ensembl:ENSG00000173166(gene)|ensembl:ENST00000319170(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016604"(nuclear body)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0048675"(axon extension)|interpro:IPR000159(Ras-association)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR039664|interpro:IPR039665|rcsb pdb:4GMV|rcsb pdb:4GN1	-	-	-	figure legend:sf1a-c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/02/06	2014/10/16	rogid:mAk7M0s5Dd2Qoa/e1rPYvVcV3xs9606	rogid:gvrXafpck5vbLuP/cmMV69yJgzs9606	intact-crc:F8DE0EF6DBE371D2|rigid:T2GbKFVD6QKrib8Y5qPS7u4XW5A	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:Q99963	uniprotkb:Q70E73	intact:EBI-473910|uniprotkb:O43553|uniprotkb:O43554|ensembl:ENSP00000391372	intact:EBI-3940924|uniprotkb:Q9C0I2|uniprotkb:Q96Q37|ensembl:ENSP00000316543	psi-mi:sh3g3_human(display_long)|uniprotkb:Endophilin-3(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 3(gene name synonym)|uniprotkb:SH3 domain protein 2C(gene name synonym)|uniprotkb:EEN-B2(gene name synonym)|uniprotkb:SH3GL3(gene name)|psi-mi:SH3GL3(display_short)|uniprotkb:CNSA3(gene name synonym)|uniprotkb:SH3D2C(gene name synonym)	psi-mi:raph1_human(display_long)|uniprotkb:RAPH1(gene name)|psi-mi:RAPH1(display_short)|uniprotkb:ALS2CR18(gene name synonym)|uniprotkb:ALS2CR9(gene name synonym)|uniprotkb:KIAA1681(gene name synonym)|uniprotkb:LPD(gene name synonym)|uniprotkb:PREL2(gene name synonym)|uniprotkb:RMO1(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 18 protein(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 9 protein(gene name synonym)|uniprotkb:Lamellipodin(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 2(gene name synonym)|uniprotkb:Protein RMO1(gene name synonym)	psi-mi:"MI:0089"(protein array)	Vehlow et al. (2013)	imex:IM-22206|pubmed:24076656	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9119140|imex:IM-22206-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001288037.1|refseq:NP_001288038.1|ensembl:ENSG00000140600(gene)|ensembl:ENST00000427482(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0006897"(endocytosis)|rcsb pdb:2Z0V|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9031628|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008289"(lipid binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0098793"(presynapse)|go:"GO:0098845"(postsynaptic endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0031901"(early endosome membrane)|go:"GO:1900186"(negative regulation of clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028501|interpro:IPR032469|interpro:IPR035824|interpro:IPR036028|mint:Q99963|rcsb pdb:2EW3|refseq:NP_003018.3|refseq:XP_011520191.1|refseq:NP_001311112.1|refseq:NP_001311114.1|refseq:NP_001311116.1|refseq:XP_016877975.1|dip:DIP-34766N	refseq:NP_976241.1|refseq:NP_998754.1|ensembl:ENST00000308091|ensembl:ENSP00000311293|ensembl:ENSP00000316543|ensembl:ENST00000418114|ensembl:ENSP00000396711|ensembl:ENST00000419464|ensembl:ENSP00000390578|ensembl:ENST00000423104|ensembl:ENSP00000397751|ensembl:ENST00000439222|ensembl:ENSP00000411138|ensembl:ENST00000453034|ensembl:ENSP00000406662|dip:DIP-61336N|ensembl:ENSG00000173166(gene)|ensembl:ENST00000319170(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016604"(nuclear body)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0048675"(axon extension)|interpro:IPR000159(Ras-association)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR039664|interpro:IPR039665|rcsb pdb:4GMV|rcsb pdb:4GN1	-	-	-	figure legend:sf1a-c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/02/06	2014/10/16	rogid:0MBJt+lIGr7wul+tAItvkg4LqIQ9606	rogid:gvrXafpck5vbLuP/cmMV69yJgzs9606	intact-crc:0DDEB7DDCBE3042E|rigid:9vymNhlKmX3lTtfG8tJPDoqdQ+Q	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:O35964	uniprotkb:Q70E73	intact:EBI-1149235|ensembl:ENSRNOP00000066789	intact:EBI-3940924|uniprotkb:Q9C0I2|uniprotkb:Q96Q37|ensembl:ENSP00000316543	psi-mi:sh3g1_rat(display_long)|uniprotkb:Endophilin-2(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 1(gene name synonym)|uniprotkb:SH3 domain protein 2B(gene name synonym)|uniprotkb:SH3p8(gene name synonym)|uniprotkb:Sh3gl1(gene name)|psi-mi:Sh3gl1(display_short)|uniprotkb:Sh3p8(gene name synonym)	psi-mi:raph1_human(display_long)|uniprotkb:RAPH1(gene name)|psi-mi:RAPH1(display_short)|uniprotkb:ALS2CR18(gene name synonym)|uniprotkb:ALS2CR9(gene name synonym)|uniprotkb:KIAA1681(gene name synonym)|uniprotkb:LPD(gene name synonym)|uniprotkb:PREL2(gene name synonym)|uniprotkb:RMO1(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 18 protein(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 9 protein(gene name synonym)|uniprotkb:Lamellipodin(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 2(gene name synonym)|uniprotkb:Protein RMO1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Vehlow et al. (2013)	imex:IM-22206|pubmed:24076656	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9119306|imex:IM-22206-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:708456|refseq:NP_112518.1|ensembl:ENSRNOG00000049683(gene)|ensembl:ENSRNOT00000074695(transcript)|go:"GO:0002102"(podosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008289"(lipid binding)|go:"GO:0016020"(membrane)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0051020"(GTPase binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|rcsb pdb:3C0C|reactome:R-RNO-182971|reactome:R-RNO-6807004|go:"GO:0017124"(SH3 domain binding)|reactome:R-RNO-8856825|reactome:R-RNO-8856828	refseq:NP_976241.1|refseq:NP_998754.1|ensembl:ENST00000308091|ensembl:ENSP00000311293|ensembl:ENSP00000316543|ensembl:ENST00000418114|ensembl:ENSP00000396711|ensembl:ENST00000419464|ensembl:ENSP00000390578|ensembl:ENST00000423104|ensembl:ENSP00000397751|ensembl:ENST00000439222|ensembl:ENSP00000411138|ensembl:ENST00000453034|ensembl:ENSP00000406662|dip:DIP-61336N|ensembl:ENSG00000173166(gene)|ensembl:ENST00000319170(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016604"(nuclear body)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0048675"(axon extension)|interpro:IPR000159(Ras-association)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR039664|interpro:IPR039665|rcsb pdb:4GMV|rcsb pdb:4GN1	-	-	-	figure legend:f1a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/02/06	2014/10/16	rogid:0aG42mdp8P/MQ8GurNZiUTipVz410116	rogid:gvrXafpck5vbLuP/cmMV69yJgzs9606	intact-crc:707BDA37F2DF20D6|rigid:/IeBGUvdsxHrSCXHIMkjRb7oBL0	false	glutathione s tranferase tag:?-?|binding-associated region:312-357	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q70E73	uniprotkb:Q99963	intact:EBI-3940924|uniprotkb:Q9C0I2|uniprotkb:Q96Q37|ensembl:ENSP00000316543	intact:EBI-473910|uniprotkb:O43553|uniprotkb:O43554|ensembl:ENSP00000391372	psi-mi:raph1_human(display_long)|uniprotkb:RAPH1(gene name)|psi-mi:RAPH1(display_short)|uniprotkb:ALS2CR18(gene name synonym)|uniprotkb:ALS2CR9(gene name synonym)|uniprotkb:KIAA1681(gene name synonym)|uniprotkb:LPD(gene name synonym)|uniprotkb:PREL2(gene name synonym)|uniprotkb:RMO1(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 18 protein(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 9 protein(gene name synonym)|uniprotkb:Lamellipodin(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 2(gene name synonym)|uniprotkb:Protein RMO1(gene name synonym)	psi-mi:sh3g3_human(display_long)|uniprotkb:Endophilin-3(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 3(gene name synonym)|uniprotkb:SH3 domain protein 2C(gene name synonym)|uniprotkb:EEN-B2(gene name synonym)|uniprotkb:SH3GL3(gene name)|psi-mi:SH3GL3(display_short)|uniprotkb:CNSA3(gene name synonym)|uniprotkb:SH3D2C(gene name synonym)	psi-mi:"MI:0096"(pull down)	Vehlow et al. (2013)	imex:IM-22206|pubmed:24076656	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9119315|imex:IM-22206-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_976241.1|refseq:NP_998754.1|ensembl:ENST00000308091|ensembl:ENSP00000311293|ensembl:ENSP00000316543|ensembl:ENST00000418114|ensembl:ENSP00000396711|ensembl:ENST00000419464|ensembl:ENSP00000390578|ensembl:ENST00000423104|ensembl:ENSP00000397751|ensembl:ENST00000439222|ensembl:ENSP00000411138|ensembl:ENST00000453034|ensembl:ENSP00000406662|dip:DIP-61336N|ensembl:ENSG00000173166(gene)|ensembl:ENST00000319170(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016604"(nuclear body)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0048675"(axon extension)|interpro:IPR000159(Ras-association)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR039664|interpro:IPR039665|rcsb pdb:4GMV|rcsb pdb:4GN1	refseq:NP_001288037.1|refseq:NP_001288038.1|ensembl:ENSG00000140600(gene)|ensembl:ENST00000427482(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0006897"(endocytosis)|rcsb pdb:2Z0V|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9031628|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008289"(lipid binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0098793"(presynapse)|go:"GO:0098845"(postsynaptic endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0031901"(early endosome membrane)|go:"GO:1900186"(negative regulation of clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028501|interpro:IPR032469|interpro:IPR035824|interpro:IPR036028|mint:Q99963|rcsb pdb:2EW3|refseq:NP_003018.3|refseq:XP_011520191.1|refseq:NP_001311112.1|refseq:NP_001311114.1|refseq:NP_001311116.1|refseq:XP_016877975.1|dip:DIP-34766N	-	-	-	figure legend:f1a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/02/06	2014/10/16	rogid:gvrXafpck5vbLuP/cmMV69yJgzs9606	rogid:0MBJt+lIGr7wul+tAItvkg4LqIQ9606	intact-crc:707BDA37F2DF20D6|rigid:9vymNhlKmX3lTtfG8tJPDoqdQ+Q	false	-	glutathione s tranferase tag:?-?|binding-associated region:285-344	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q70E73	uniprotkb:Q99962	intact:EBI-3940924|uniprotkb:Q9C0I2|uniprotkb:Q96Q37|ensembl:ENSP00000316543	intact:EBI-77938|ensembl:ENSP00000369981|uniprotkb:Q9NQK5|uniprotkb:B2R618	psi-mi:raph1_human(display_long)|uniprotkb:RAPH1(gene name)|psi-mi:RAPH1(display_short)|uniprotkb:ALS2CR18(gene name synonym)|uniprotkb:ALS2CR9(gene name synonym)|uniprotkb:KIAA1681(gene name synonym)|uniprotkb:LPD(gene name synonym)|uniprotkb:PREL2(gene name synonym)|uniprotkb:RMO1(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 18 protein(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 9 protein(gene name synonym)|uniprotkb:Lamellipodin(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 2(gene name synonym)|uniprotkb:Protein RMO1(gene name synonym)	psi-mi:sh3g2_human(display_long)|uniprotkb:SH3GL2(gene name)|psi-mi:SH3GL2(display_short)|uniprotkb:CNSA2(gene name synonym)|uniprotkb:SH3D2A(gene name synonym)|uniprotkb:Endophilin-1(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 2(gene name synonym)|uniprotkb:SH3 domain protein 2A(gene name synonym)|uniprotkb:EEN-B1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Vehlow et al. (2013)	imex:IM-22206|pubmed:24076656	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9119297|imex:IM-22206-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_976241.1|refseq:NP_998754.1|ensembl:ENST00000308091|ensembl:ENSP00000311293|ensembl:ENSP00000316543|ensembl:ENST00000418114|ensembl:ENSP00000396711|ensembl:ENST00000419464|ensembl:ENSP00000390578|ensembl:ENST00000423104|ensembl:ENSP00000397751|ensembl:ENST00000439222|ensembl:ENSP00000411138|ensembl:ENST00000453034|ensembl:ENSP00000406662|dip:DIP-61336N|ensembl:ENSG00000173166(gene)|ensembl:ENST00000319170(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016604"(nuclear body)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0048675"(axon extension)|interpro:IPR000159(Ras-association)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR039664|interpro:IPR039665|rcsb pdb:4GMV|rcsb pdb:4GN1	go:"GO:0097749"(membrane tubulation)|go:"GO:0097753"(membrane bending)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099050"(vesicle scission)|go:"GO:1903527"(positive regulation of membrane tubulation)|go:"GO:1905604"(negative regulation of blood-brain barrier permeability)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:2000369"(regulation of clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035824|interpro:IPR036028|mint:Q99962|rcsb pdb:1X03|rcsb pdb:1X04|rcsb pdb:2D4C|rcsb pdb:2DBM|reactome:R-HSA-177504|reactome:R-HSA-182971|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|ensembl:ENSG00000107295(gene)|ensembl:ENST00000380607(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0097441"(basal dendrite)|go:"GO:0097484"(dendrite extension)|refseq:NP_003017.1|dip:DIP-30996N	-	-	-	figure legend:f1a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/02/06	2014/10/16	rogid:gvrXafpck5vbLuP/cmMV69yJgzs9606	rogid:mAk7M0s5Dd2Qoa/e1rPYvVcV3xs9606	intact-crc:2231DC7D8673D948|rigid:T2GbKFVD6QKrib8Y5qPS7u4XW5A	false	-	glutathione s tranferase tag:?-?|binding-associated region:297-345	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:F2Z3U3	uniprotkb:Q62421	intact:EBI-9119343|ensembl:ENSMUSP00000121023	intact:EBI-5276163|uniprotkb:Q8R0B7	psi-mi:f2z3u3_mouse(display_long)|uniprotkb:Raph1(gene name)|psi-mi:Raph1(display_short)	psi-mi:sh3g3_mouse(display_long)|uniprotkb:Sh3gl3(gene name)|psi-mi:Sh3gl3(display_short)|uniprotkb:Sh3d2c(gene name synonym)|uniprotkb:Sh3d2c2(gene name synonym)|uniprotkb:Endophilin-3(gene name synonym)|uniprotkb:SH3 domain protein 2C(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 3(gene name synonym)|uniprotkb:SH3p13(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Vehlow et al. (2013)	imex:IM-22206|pubmed:24076656	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9119324|imex:IM-22206-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000026014(gene)|ensembl:ENSMUST00000140485(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016604"(nuclear body)|go:"GO:0031252"(cell leading edge)|go:"GO:0048675"(axon extension)|interpro:IPR000159(Ras-association)|refseq:NP_001038978.3|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR039664|interpro:IPR039665	interpro:IPR027267|refseq:NP_059096.3|interpro:IPR004148(BAR)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|interpro:IPR032469|interpro:IPR028501|interpro:IPR035824|reactome:R-MMU-182971|reactome:R-MMU-6807004|reactome:R-MMU-8856825|reactome:R-MMU-8856828|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008289"(lipid binding)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0098793"(presynapse)|go:"GO:0098845"(postsynaptic endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900186"(negative regulation of clathrin-dependent endocytosis)|go:"GO:2000369"(regulation of clathrin-dependent endocytosis)	-	-	-	figure legend:f1b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells)	-	2014/02/06	2014/10/16	rogid:d4IGt35ZAKJHcSZGoPSaj/9OGx010090	rogid:3sPAPXYHcYlcxZSNSjIkDy29J1I10090	intact-crc:9190FDEF2DED045F|rigid:bDOuxUllCsJpTGn8oz0FcoU11WY	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q6PFA2	uniprotkb:Q70E73	intact:EBI-1634219|ensembl:ENSMUSP00000103478|ensembl:ENSMUSP00000127344	intact:EBI-3940924|uniprotkb:Q9C0I2|uniprotkb:Q96Q37|ensembl:ENSP00000316543	psi-mi:q6pfa2_mouse(display_long)|uniprotkb:Clta(gene name)|psi-mi:Clta(display_short)	psi-mi:raph1_human(display_long)|uniprotkb:RAPH1(gene name)|psi-mi:RAPH1(display_short)|uniprotkb:ALS2CR18(gene name synonym)|uniprotkb:ALS2CR9(gene name synonym)|uniprotkb:KIAA1681(gene name synonym)|uniprotkb:LPD(gene name synonym)|uniprotkb:PREL2(gene name synonym)|uniprotkb:RMO1(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 18 protein(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 9 protein(gene name synonym)|uniprotkb:Lamellipodin(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 2(gene name synonym)|uniprotkb:Protein RMO1(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Vehlow et al. (2013)	imex:IM-22206|pubmed:24076656	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-9160566|imex:IM-22206-26	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001277399.1|refseq:NP_001073853.1|refseq:XP_006537653.1|ensembl:ENSMUSG00000028478(gene)|ensembl:ENSMUST00000107846(transcript)|ensembl:ENSMUST00000170241(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|interpro:IPR000996(Clathrin light chain)	refseq:NP_976241.1|refseq:NP_998754.1|ensembl:ENST00000308091|ensembl:ENSP00000311293|ensembl:ENSP00000316543|ensembl:ENST00000418114|ensembl:ENSP00000396711|ensembl:ENST00000419464|ensembl:ENSP00000390578|ensembl:ENST00000423104|ensembl:ENSP00000397751|ensembl:ENST00000439222|ensembl:ENSP00000411138|ensembl:ENST00000453034|ensembl:ENSP00000406662|dip:DIP-61336N|ensembl:ENSG00000173166(gene)|ensembl:ENST00000319170(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016604"(nuclear body)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0048675"(axon extension)|interpro:IPR000159(Ras-association)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR039664|interpro:IPR039665|rcsb pdb:4GMV|rcsb pdb:4GN1	-	-	-	figure legend:f4g f4i f4j|comment:"On average 28% of clathrin spots colocalized with Lpd, whereas 53% of Lpd‐positive spots colocalized with clathrin (Figure 4G), suggesting that Lpd is dynamically recruited to CCPs."|comment:"To analyse whether Lpd dynamically localizes to CCPs, we quantified Lpd recruitment during CCP scission in TIRFM movies. This analysis revealed that Lpd‐GFP colocalized with 57% of mRFP‐Clc labelled CCPs shortly before their scission (Figure 4I and J; Supplementary Movie S3)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/02/06	2014/10/16	rogid:LlnRbz6pNaDbFGKo/zVtbVKYdms10090	rogid:gvrXafpck5vbLuP/cmMV69yJgzs9606	intact-crc:9C5DDBBF690610B7|rigid:PHcSIFG9fNwaOplKDNFlG39ZQsQ	false	red fluorescent protein tag:?-?	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q99962	uniprotkb:Q70E73	intact:EBI-77938|ensembl:ENSP00000369981|uniprotkb:Q9NQK5|uniprotkb:B2R618	intact:EBI-3940924|uniprotkb:Q9C0I2|uniprotkb:Q96Q37|ensembl:ENSP00000316543	psi-mi:sh3g2_human(display_long)|uniprotkb:SH3GL2(gene name)|psi-mi:SH3GL2(display_short)|uniprotkb:CNSA2(gene name synonym)|uniprotkb:SH3D2A(gene name synonym)|uniprotkb:Endophilin-1(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 2(gene name synonym)|uniprotkb:SH3 domain protein 2A(gene name synonym)|uniprotkb:EEN-B1(gene name synonym)	psi-mi:raph1_human(display_long)|uniprotkb:RAPH1(gene name)|psi-mi:RAPH1(display_short)|uniprotkb:ALS2CR18(gene name synonym)|uniprotkb:ALS2CR9(gene name synonym)|uniprotkb:KIAA1681(gene name synonym)|uniprotkb:LPD(gene name synonym)|uniprotkb:PREL2(gene name synonym)|uniprotkb:RMO1(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 18 protein(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 9 protein(gene name synonym)|uniprotkb:Lamellipodin(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 2(gene name synonym)|uniprotkb:Protein RMO1(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Vehlow et al. (2013)	imex:IM-22206|pubmed:24076656	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-9119931|imex:IM-22206-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0097749"(membrane tubulation)|go:"GO:0097753"(membrane bending)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099050"(vesicle scission)|go:"GO:1903527"(positive regulation of membrane tubulation)|go:"GO:1905604"(negative regulation of blood-brain barrier permeability)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:2000369"(regulation of clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035824|interpro:IPR036028|mint:Q99962|rcsb pdb:1X03|rcsb pdb:1X04|rcsb pdb:2D4C|rcsb pdb:2DBM|reactome:R-HSA-177504|reactome:R-HSA-182971|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|ensembl:ENSG00000107295(gene)|ensembl:ENST00000380607(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0097441"(basal dendrite)|go:"GO:0097484"(dendrite extension)|refseq:NP_003017.1|dip:DIP-30996N	refseq:NP_976241.1|refseq:NP_998754.1|ensembl:ENST00000308091|ensembl:ENSP00000311293|ensembl:ENSP00000316543|ensembl:ENST00000418114|ensembl:ENSP00000396711|ensembl:ENST00000419464|ensembl:ENSP00000390578|ensembl:ENST00000423104|ensembl:ENSP00000397751|ensembl:ENST00000439222|ensembl:ENSP00000411138|ensembl:ENST00000453034|ensembl:ENSP00000406662|dip:DIP-61336N|ensembl:ENSG00000173166(gene)|ensembl:ENST00000319170(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016604"(nuclear body)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0048675"(axon extension)|interpro:IPR000159(Ras-association)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR039664|interpro:IPR039665|rcsb pdb:4GMV|rcsb pdb:4GN1	go:"GO:0005886"(plasma membrane)	-	-	figure legend:f1c f1f|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/02/06	2014/10/16	rogid:mAk7M0s5Dd2Qoa/e1rPYvVcV3xs9606	rogid:gvrXafpck5vbLuP/cmMV69yJgzs9606	intact-crc:C43B4935395002F1|rigid:T2GbKFVD6QKrib8Y5qPS7u4XW5A	false	green fluorescent protein tag:?-?	mcherry fluorescent protein tag:?-?	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q70E73	uniprotkb:Q99963	intact:EBI-3940924|uniprotkb:Q9C0I2|uniprotkb:Q96Q37|ensembl:ENSP00000316543	intact:EBI-473910|uniprotkb:O43553|uniprotkb:O43554|ensembl:ENSP00000391372	psi-mi:raph1_human(display_long)|uniprotkb:RAPH1(gene name)|psi-mi:RAPH1(display_short)|uniprotkb:ALS2CR18(gene name synonym)|uniprotkb:ALS2CR9(gene name synonym)|uniprotkb:KIAA1681(gene name synonym)|uniprotkb:LPD(gene name synonym)|uniprotkb:PREL2(gene name synonym)|uniprotkb:RMO1(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 18 protein(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 9 protein(gene name synonym)|uniprotkb:Lamellipodin(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 2(gene name synonym)|uniprotkb:Protein RMO1(gene name synonym)	psi-mi:sh3g3_human(display_long)|uniprotkb:Endophilin-3(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 3(gene name synonym)|uniprotkb:SH3 domain protein 2C(gene name synonym)|uniprotkb:EEN-B2(gene name synonym)|uniprotkb:SH3GL3(gene name)|psi-mi:SH3GL3(display_short)|uniprotkb:CNSA3(gene name synonym)|uniprotkb:SH3D2C(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Vehlow et al. (2013)	imex:IM-22206|pubmed:24076656	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-9120387|imex:IM-22206-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_976241.1|refseq:NP_998754.1|ensembl:ENST00000308091|ensembl:ENSP00000311293|ensembl:ENSP00000316543|ensembl:ENST00000418114|ensembl:ENSP00000396711|ensembl:ENST00000419464|ensembl:ENSP00000390578|ensembl:ENST00000423104|ensembl:ENSP00000397751|ensembl:ENST00000439222|ensembl:ENSP00000411138|ensembl:ENST00000453034|ensembl:ENSP00000406662|dip:DIP-61336N|ensembl:ENSG00000173166(gene)|ensembl:ENST00000319170(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016604"(nuclear body)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0048675"(axon extension)|interpro:IPR000159(Ras-association)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR039664|interpro:IPR039665|rcsb pdb:4GMV|rcsb pdb:4GN1	refseq:NP_001288037.1|refseq:NP_001288038.1|ensembl:ENSG00000140600(gene)|ensembl:ENST00000427482(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0006897"(endocytosis)|rcsb pdb:2Z0V|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9031628|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008289"(lipid binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0098793"(presynapse)|go:"GO:0098845"(postsynaptic endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0031901"(early endosome membrane)|go:"GO:1900186"(negative regulation of clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028501|interpro:IPR032469|interpro:IPR035824|interpro:IPR036028|mint:Q99963|rcsb pdb:2EW3|refseq:NP_003018.3|refseq:XP_011520191.1|refseq:NP_001311112.1|refseq:NP_001311114.1|refseq:NP_001311116.1|refseq:XP_016877975.1|dip:DIP-34766N	go:"GO:0005886"(plasma membrane)	-	-	figure legend:f1e f1f f2|comment:"To identify the part of Lpd that interacts with the SH3 domain of endophilin, we generated different truncation mutants of Lpd tagged with mCherry (Figure 2A) and co‐expressed them with GFP‐endophilin A3 in HeLa cells. We scored colocalization of both proteins in cells in which the expression of endophilin A3 caused membrane tubulation. As expected, we did not observe colocalization of the two C‐terminal truncation mutants of Lpd (Lpd‐N1, Lpd‐N2) with endophilin A3, as these do not contain SH3 domain‐binding sites (Figure 2B and C). However, all N‐terminal truncated Lpd constructs containing proline‐rich regions colocalized with endophilin A3 (Figure 2B and C), suggesting that the endophilin SH3 domain binds to various proline‐rich regions in the Lpd sequence."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/02/06	2014/10/16	rogid:gvrXafpck5vbLuP/cmMV69yJgzs9606	rogid:0MBJt+lIGr7wul+tAItvkg4LqIQ9606	intact-crc:61A592393C88F68C|rigid:9vymNhlKmX3lTtfG8tJPDoqdQ+Q	false	mcherry fluorescent protein tag:?-?	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:O35964	uniprotkb:Q70E73	intact:EBI-1149235|ensembl:ENSRNOP00000066789	intact:EBI-3940924|uniprotkb:Q9C0I2|uniprotkb:Q96Q37|ensembl:ENSP00000316543	psi-mi:sh3g1_rat(display_long)|uniprotkb:Endophilin-2(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 1(gene name synonym)|uniprotkb:SH3 domain protein 2B(gene name synonym)|uniprotkb:SH3p8(gene name synonym)|uniprotkb:Sh3gl1(gene name)|psi-mi:Sh3gl1(display_short)|uniprotkb:Sh3p8(gene name synonym)	psi-mi:raph1_human(display_long)|uniprotkb:RAPH1(gene name)|psi-mi:RAPH1(display_short)|uniprotkb:ALS2CR18(gene name synonym)|uniprotkb:ALS2CR9(gene name synonym)|uniprotkb:KIAA1681(gene name synonym)|uniprotkb:LPD(gene name synonym)|uniprotkb:PREL2(gene name synonym)|uniprotkb:RMO1(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 18 protein(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 9 protein(gene name synonym)|uniprotkb:Lamellipodin(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 2(gene name synonym)|uniprotkb:Protein RMO1(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Vehlow et al. (2013)	imex:IM-22206|pubmed:24076656	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-9120378|imex:IM-22206-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:708456|refseq:NP_112518.1|ensembl:ENSRNOG00000049683(gene)|ensembl:ENSRNOT00000074695(transcript)|go:"GO:0002102"(podosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008289"(lipid binding)|go:"GO:0016020"(membrane)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0051020"(GTPase binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|rcsb pdb:3C0C|reactome:R-RNO-182971|reactome:R-RNO-6807004|go:"GO:0017124"(SH3 domain binding)|reactome:R-RNO-8856825|reactome:R-RNO-8856828	refseq:NP_976241.1|refseq:NP_998754.1|ensembl:ENST00000308091|ensembl:ENSP00000311293|ensembl:ENSP00000316543|ensembl:ENST00000418114|ensembl:ENSP00000396711|ensembl:ENST00000419464|ensembl:ENSP00000390578|ensembl:ENST00000423104|ensembl:ENSP00000397751|ensembl:ENST00000439222|ensembl:ENSP00000411138|ensembl:ENST00000453034|ensembl:ENSP00000406662|dip:DIP-61336N|ensembl:ENSG00000173166(gene)|ensembl:ENST00000319170(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016604"(nuclear body)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0048675"(axon extension)|interpro:IPR000159(Ras-association)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR039664|interpro:IPR039665|rcsb pdb:4GMV|rcsb pdb:4GN1	go:"GO:0005886"(plasma membrane)	-	-	figure legend:f1d f1f|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/02/06	2014/10/16	rogid:0aG42mdp8P/MQ8GurNZiUTipVz410116	rogid:gvrXafpck5vbLuP/cmMV69yJgzs9606	intact-crc:5548D84765557DC2|rigid:/IeBGUvdsxHrSCXHIMkjRb7oBL0	false	green fluorescent protein tag:?-?	mcherry fluorescent protein tag:?-?	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:O35964	uniprotkb:Q70E73	intact:EBI-1149235|ensembl:ENSRNOP00000066789	intact:EBI-3940924|uniprotkb:Q9C0I2|uniprotkb:Q96Q37|ensembl:ENSP00000316543	psi-mi:sh3g1_rat(display_long)|uniprotkb:Endophilin-2(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 1(gene name synonym)|uniprotkb:SH3 domain protein 2B(gene name synonym)|uniprotkb:SH3p8(gene name synonym)|uniprotkb:Sh3gl1(gene name)|psi-mi:Sh3gl1(display_short)|uniprotkb:Sh3p8(gene name synonym)	psi-mi:raph1_human(display_long)|uniprotkb:RAPH1(gene name)|psi-mi:RAPH1(display_short)|uniprotkb:ALS2CR18(gene name synonym)|uniprotkb:ALS2CR9(gene name synonym)|uniprotkb:KIAA1681(gene name synonym)|uniprotkb:LPD(gene name synonym)|uniprotkb:PREL2(gene name synonym)|uniprotkb:RMO1(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 18 protein(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 9 protein(gene name synonym)|uniprotkb:Lamellipodin(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 2(gene name synonym)|uniprotkb:Protein RMO1(gene name synonym)	psi-mi:"MI:0047"(far western blotting)	Vehlow et al. (2013)	imex:IM-22206|pubmed:24076656	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9136254|imex:IM-22206-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:708456|refseq:NP_112518.1|ensembl:ENSRNOG00000049683(gene)|ensembl:ENSRNOT00000074695(transcript)|go:"GO:0002102"(podosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008289"(lipid binding)|go:"GO:0016020"(membrane)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0051020"(GTPase binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|rcsb pdb:3C0C|reactome:R-RNO-182971|reactome:R-RNO-6807004|go:"GO:0017124"(SH3 domain binding)|reactome:R-RNO-8856825|reactome:R-RNO-8856828	refseq:NP_976241.1|refseq:NP_998754.1|ensembl:ENST00000308091|ensembl:ENSP00000311293|ensembl:ENSP00000316543|ensembl:ENST00000418114|ensembl:ENSP00000396711|ensembl:ENST00000419464|ensembl:ENSP00000390578|ensembl:ENST00000423104|ensembl:ENSP00000397751|ensembl:ENST00000439222|ensembl:ENSP00000411138|ensembl:ENST00000453034|ensembl:ENSP00000406662|dip:DIP-61336N|ensembl:ENSG00000173166(gene)|ensembl:ENST00000319170(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016604"(nuclear body)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0048675"(axon extension)|interpro:IPR000159(Ras-association)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR039664|interpro:IPR039665|rcsb pdb:4GMV|rcsb pdb:4GN1	-	-	-	figure legend:f3b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/02/06	2014/10/16	rogid:0aG42mdp8P/MQ8GurNZiUTipVz410116	rogid:gvrXafpck5vbLuP/cmMV69yJgzs9606	intact-crc:0816EBA98F3DDCC5|rigid:/IeBGUvdsxHrSCXHIMkjRb7oBL0	false	binding-associated region:312-357|maltose binding protein tag:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99963	uniprotkb:Q70E73	intact:EBI-473910|uniprotkb:O43553|uniprotkb:O43554|ensembl:ENSP00000391372	intact:EBI-3940924|uniprotkb:Q9C0I2|uniprotkb:Q96Q37|ensembl:ENSP00000316543	psi-mi:sh3g3_human(display_long)|uniprotkb:Endophilin-3(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 3(gene name synonym)|uniprotkb:SH3 domain protein 2C(gene name synonym)|uniprotkb:EEN-B2(gene name synonym)|uniprotkb:SH3GL3(gene name)|psi-mi:SH3GL3(display_short)|uniprotkb:CNSA3(gene name synonym)|uniprotkb:SH3D2C(gene name synonym)	psi-mi:raph1_human(display_long)|uniprotkb:RAPH1(gene name)|psi-mi:RAPH1(display_short)|uniprotkb:ALS2CR18(gene name synonym)|uniprotkb:ALS2CR9(gene name synonym)|uniprotkb:KIAA1681(gene name synonym)|uniprotkb:LPD(gene name synonym)|uniprotkb:PREL2(gene name synonym)|uniprotkb:RMO1(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 18 protein(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 9 protein(gene name synonym)|uniprotkb:Lamellipodin(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 2(gene name synonym)|uniprotkb:Protein RMO1(gene name synonym)	psi-mi:"MI:0047"(far western blotting)	Vehlow et al. (2013)	imex:IM-22206|pubmed:24076656	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9137109|imex:IM-22206-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001288037.1|refseq:NP_001288038.1|ensembl:ENSG00000140600(gene)|ensembl:ENST00000427482(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0006897"(endocytosis)|rcsb pdb:2Z0V|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9031628|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008289"(lipid binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0098793"(presynapse)|go:"GO:0098845"(postsynaptic endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0031901"(early endosome membrane)|go:"GO:1900186"(negative regulation of clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028501|interpro:IPR032469|interpro:IPR035824|interpro:IPR036028|mint:Q99963|rcsb pdb:2EW3|refseq:NP_003018.3|refseq:XP_011520191.1|refseq:NP_001311112.1|refseq:NP_001311114.1|refseq:NP_001311116.1|refseq:XP_016877975.1|dip:DIP-34766N	refseq:NP_976241.1|refseq:NP_998754.1|ensembl:ENST00000308091|ensembl:ENSP00000311293|ensembl:ENSP00000316543|ensembl:ENST00000418114|ensembl:ENSP00000396711|ensembl:ENST00000419464|ensembl:ENSP00000390578|ensembl:ENST00000423104|ensembl:ENSP00000397751|ensembl:ENST00000439222|ensembl:ENSP00000411138|ensembl:ENST00000453034|ensembl:ENSP00000406662|dip:DIP-61336N|ensembl:ENSG00000173166(gene)|ensembl:ENST00000319170(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016604"(nuclear body)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0048675"(axon extension)|interpro:IPR000159(Ras-association)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR039664|interpro:IPR039665|rcsb pdb:4GMV|rcsb pdb:4GN1	-	-	-	figure legend:f3c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/02/06	2014/10/16	rogid:0MBJt+lIGr7wul+tAItvkg4LqIQ9606	rogid:gvrXafpck5vbLuP/cmMV69yJgzs9606	intact-crc:8F62F729E4AB94BD|rigid:9vymNhlKmX3lTtfG8tJPDoqdQ+Q	false	maltose binding protein tag:?-?|binding-associated region:285-344	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q99962	uniprotkb:Q70E73	intact:EBI-77938|ensembl:ENSP00000369981|uniprotkb:Q9NQK5|uniprotkb:B2R618	intact:EBI-3940924|uniprotkb:Q9C0I2|uniprotkb:Q96Q37|ensembl:ENSP00000316543	psi-mi:sh3g2_human(display_long)|uniprotkb:SH3GL2(gene name)|psi-mi:SH3GL2(display_short)|uniprotkb:CNSA2(gene name synonym)|uniprotkb:SH3D2A(gene name synonym)|uniprotkb:Endophilin-1(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 2(gene name synonym)|uniprotkb:SH3 domain protein 2A(gene name synonym)|uniprotkb:EEN-B1(gene name synonym)	psi-mi:raph1_human(display_long)|uniprotkb:RAPH1(gene name)|psi-mi:RAPH1(display_short)|uniprotkb:ALS2CR18(gene name synonym)|uniprotkb:ALS2CR9(gene name synonym)|uniprotkb:KIAA1681(gene name synonym)|uniprotkb:LPD(gene name synonym)|uniprotkb:PREL2(gene name synonym)|uniprotkb:RMO1(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 18 protein(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 9 protein(gene name synonym)|uniprotkb:Lamellipodin(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 2(gene name synonym)|uniprotkb:Protein RMO1(gene name synonym)	psi-mi:"MI:0047"(far western blotting)	Vehlow et al. (2013)	imex:IM-22206|pubmed:24076656	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9133784|imex:IM-22206-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0097749"(membrane tubulation)|go:"GO:0097753"(membrane bending)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099050"(vesicle scission)|go:"GO:1903527"(positive regulation of membrane tubulation)|go:"GO:1905604"(negative regulation of blood-brain barrier permeability)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:2000369"(regulation of clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035824|interpro:IPR036028|mint:Q99962|rcsb pdb:1X03|rcsb pdb:1X04|rcsb pdb:2D4C|rcsb pdb:2DBM|reactome:R-HSA-177504|reactome:R-HSA-182971|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|ensembl:ENSG00000107295(gene)|ensembl:ENST00000380607(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0097441"(basal dendrite)|go:"GO:0097484"(dendrite extension)|refseq:NP_003017.1|dip:DIP-30996N	refseq:NP_976241.1|refseq:NP_998754.1|ensembl:ENST00000308091|ensembl:ENSP00000311293|ensembl:ENSP00000316543|ensembl:ENST00000418114|ensembl:ENSP00000396711|ensembl:ENST00000419464|ensembl:ENSP00000390578|ensembl:ENST00000423104|ensembl:ENSP00000397751|ensembl:ENST00000439222|ensembl:ENSP00000411138|ensembl:ENST00000453034|ensembl:ENSP00000406662|dip:DIP-61336N|ensembl:ENSG00000173166(gene)|ensembl:ENST00000319170(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016604"(nuclear body)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0048675"(axon extension)|interpro:IPR000159(Ras-association)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR039664|interpro:IPR039665|rcsb pdb:4GMV|rcsb pdb:4GN1	-	-	-	figure legend:f3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/02/06	2014/10/16	rogid:mAk7M0s5Dd2Qoa/e1rPYvVcV3xs9606	rogid:gvrXafpck5vbLuP/cmMV69yJgzs9606	intact-crc:A796564011647B27|rigid:T2GbKFVD6QKrib8Y5qPS7u4XW5A	false	maltose binding protein tag:?-?|binding-associated region:297-345	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O35964	uniprotkb:Q70E73	intact:EBI-1149235|ensembl:ENSRNOP00000066789	intact:EBI-3940924|uniprotkb:Q9C0I2|uniprotkb:Q96Q37|ensembl:ENSP00000316543	psi-mi:sh3g1_rat(display_long)|uniprotkb:Endophilin-2(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 1(gene name synonym)|uniprotkb:SH3 domain protein 2B(gene name synonym)|uniprotkb:SH3p8(gene name synonym)|uniprotkb:Sh3gl1(gene name)|psi-mi:Sh3gl1(display_short)|uniprotkb:Sh3p8(gene name synonym)	psi-mi:raph1_human(display_long)|uniprotkb:RAPH1(gene name)|psi-mi:RAPH1(display_short)|uniprotkb:ALS2CR18(gene name synonym)|uniprotkb:ALS2CR9(gene name synonym)|uniprotkb:KIAA1681(gene name synonym)|uniprotkb:LPD(gene name synonym)|uniprotkb:PREL2(gene name synonym)|uniprotkb:RMO1(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 18 protein(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 9 protein(gene name synonym)|uniprotkb:Lamellipodin(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 2(gene name synonym)|uniprotkb:Protein RMO1(gene name synonym)	psi-mi:"MI:0081"(peptide array)	Vehlow et al. (2013)	imex:IM-22206|pubmed:24076656	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9150769|imex:IM-22206-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:708456|refseq:NP_112518.1|ensembl:ENSRNOG00000049683(gene)|ensembl:ENSRNOT00000074695(transcript)|go:"GO:0002102"(podosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008289"(lipid binding)|go:"GO:0016020"(membrane)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0051020"(GTPase binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|rcsb pdb:3C0C|reactome:R-RNO-182971|reactome:R-RNO-6807004|go:"GO:0017124"(SH3 domain binding)|reactome:R-RNO-8856825|reactome:R-RNO-8856828	refseq:NP_976241.1|refseq:NP_998754.1|ensembl:ENST00000308091|ensembl:ENSP00000311293|ensembl:ENSP00000316543|ensembl:ENST00000418114|ensembl:ENSP00000396711|ensembl:ENST00000419464|ensembl:ENSP00000390578|ensembl:ENST00000423104|ensembl:ENSP00000397751|ensembl:ENST00000439222|ensembl:ENSP00000411138|ensembl:ENST00000453034|ensembl:ENSP00000406662|dip:DIP-61336N|ensembl:ENSG00000173166(gene)|ensembl:ENST00000319170(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016604"(nuclear body)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0048675"(axon extension)|interpro:IPR000159(Ras-association)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR039664|interpro:IPR039665|rcsb pdb:4GMV|rcsb pdb:4GN1	-	-	-	figure legend:f3e sf2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/02/06	2014/10/16	rogid:0aG42mdp8P/MQ8GurNZiUTipVz410116	rogid:gvrXafpck5vbLuP/cmMV69yJgzs9606	intact-crc:C910DB37680648C6|rigid:/IeBGUvdsxHrSCXHIMkjRb7oBL0	false	maltose binding protein tag:?-?|binding-associated region:312-357	glutathione s tranferase tag:?-?|binding-associated region:1120-1131	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0083"(peptide synthesis)
uniprotkb:O35964	uniprotkb:Q70E73	intact:EBI-1149235|ensembl:ENSRNOP00000066789	intact:EBI-3940924|uniprotkb:Q9C0I2|uniprotkb:Q96Q37|ensembl:ENSP00000316543	psi-mi:sh3g1_rat(display_long)|uniprotkb:Endophilin-2(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 1(gene name synonym)|uniprotkb:SH3 domain protein 2B(gene name synonym)|uniprotkb:SH3p8(gene name synonym)|uniprotkb:Sh3gl1(gene name)|psi-mi:Sh3gl1(display_short)|uniprotkb:Sh3p8(gene name synonym)	psi-mi:raph1_human(display_long)|uniprotkb:RAPH1(gene name)|psi-mi:RAPH1(display_short)|uniprotkb:ALS2CR18(gene name synonym)|uniprotkb:ALS2CR9(gene name synonym)|uniprotkb:KIAA1681(gene name synonym)|uniprotkb:LPD(gene name synonym)|uniprotkb:PREL2(gene name synonym)|uniprotkb:RMO1(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 18 protein(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 9 protein(gene name synonym)|uniprotkb:Lamellipodin(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 2(gene name synonym)|uniprotkb:Protein RMO1(gene name synonym)	psi-mi:"MI:0081"(peptide array)	Vehlow et al. (2013)	imex:IM-22206|pubmed:24076656	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9150113|imex:IM-22206-20	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:708456|refseq:NP_112518.1|ensembl:ENSRNOG00000049683(gene)|ensembl:ENSRNOT00000074695(transcript)|go:"GO:0002102"(podosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008289"(lipid binding)|go:"GO:0016020"(membrane)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0051020"(GTPase binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|rcsb pdb:3C0C|reactome:R-RNO-182971|reactome:R-RNO-6807004|go:"GO:0017124"(SH3 domain binding)|reactome:R-RNO-8856825|reactome:R-RNO-8856828	refseq:NP_976241.1|refseq:NP_998754.1|ensembl:ENST00000308091|ensembl:ENSP00000311293|ensembl:ENSP00000316543|ensembl:ENST00000418114|ensembl:ENSP00000396711|ensembl:ENST00000419464|ensembl:ENSP00000390578|ensembl:ENST00000423104|ensembl:ENSP00000397751|ensembl:ENST00000439222|ensembl:ENSP00000411138|ensembl:ENST00000453034|ensembl:ENSP00000406662|dip:DIP-61336N|ensembl:ENSG00000173166(gene)|ensembl:ENST00000319170(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016604"(nuclear body)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0048675"(axon extension)|interpro:IPR000159(Ras-association)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR039664|interpro:IPR039665|rcsb pdb:4GMV|rcsb pdb:4GN1	-	-	-	figure legend:f3e sf2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/02/06	2014/10/16	rogid:0aG42mdp8P/MQ8GurNZiUTipVz410116	rogid:gvrXafpck5vbLuP/cmMV69yJgzs9606	intact-crc:F2A08B99566895CE|rigid:/IeBGUvdsxHrSCXHIMkjRb7oBL0	false	maltose binding protein tag:?-?|binding-associated region:312-357	binding-associated region:970-981|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0083"(peptide synthesis)
uniprotkb:O35964	uniprotkb:Q70E73	intact:EBI-1149235|ensembl:ENSRNOP00000066789	intact:EBI-3940924|uniprotkb:Q9C0I2|uniprotkb:Q96Q37|ensembl:ENSP00000316543	psi-mi:sh3g1_rat(display_long)|uniprotkb:Endophilin-2(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 1(gene name synonym)|uniprotkb:SH3 domain protein 2B(gene name synonym)|uniprotkb:SH3p8(gene name synonym)|uniprotkb:Sh3gl1(gene name)|psi-mi:Sh3gl1(display_short)|uniprotkb:Sh3p8(gene name synonym)	psi-mi:raph1_human(display_long)|uniprotkb:RAPH1(gene name)|psi-mi:RAPH1(display_short)|uniprotkb:ALS2CR18(gene name synonym)|uniprotkb:ALS2CR9(gene name synonym)|uniprotkb:KIAA1681(gene name synonym)|uniprotkb:LPD(gene name synonym)|uniprotkb:PREL2(gene name synonym)|uniprotkb:RMO1(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 18 protein(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 9 protein(gene name synonym)|uniprotkb:Lamellipodin(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 2(gene name synonym)|uniprotkb:Protein RMO1(gene name synonym)	psi-mi:"MI:0081"(peptide array)	Vehlow et al. (2013)	imex:IM-22206|pubmed:24076656	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9151561|imex:IM-22206-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:708456|refseq:NP_112518.1|ensembl:ENSRNOG00000049683(gene)|ensembl:ENSRNOT00000074695(transcript)|go:"GO:0002102"(podosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008289"(lipid binding)|go:"GO:0016020"(membrane)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0051020"(GTPase binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|rcsb pdb:3C0C|reactome:R-RNO-182971|reactome:R-RNO-6807004|go:"GO:0017124"(SH3 domain binding)|reactome:R-RNO-8856825|reactome:R-RNO-8856828	refseq:NP_976241.1|refseq:NP_998754.1|ensembl:ENST00000308091|ensembl:ENSP00000311293|ensembl:ENSP00000316543|ensembl:ENST00000418114|ensembl:ENSP00000396711|ensembl:ENST00000419464|ensembl:ENSP00000390578|ensembl:ENST00000423104|ensembl:ENSP00000397751|ensembl:ENST00000439222|ensembl:ENSP00000411138|ensembl:ENST00000453034|ensembl:ENSP00000406662|dip:DIP-61336N|ensembl:ENSG00000173166(gene)|ensembl:ENST00000319170(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016604"(nuclear body)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0048675"(axon extension)|interpro:IPR000159(Ras-association)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR039664|interpro:IPR039665|rcsb pdb:4GMV|rcsb pdb:4GN1	-	-	-	figure legend:f3e sf2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/02/06	2014/10/16	rogid:0aG42mdp8P/MQ8GurNZiUTipVz410116	rogid:gvrXafpck5vbLuP/cmMV69yJgzs9606	intact-crc:4EA79AE8C25FB53F|rigid:/IeBGUvdsxHrSCXHIMkjRb7oBL0	false	binding-associated region:312-357|maltose binding protein tag:?-?	glutathione s tranferase tag:?-?|binding-associated region:1228-1239	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0083"(peptide synthesis)
uniprotkb:O35964	uniprotkb:Q70E73	intact:EBI-1149235|ensembl:ENSRNOP00000066789	intact:EBI-3940924|uniprotkb:Q9C0I2|uniprotkb:Q96Q37|ensembl:ENSP00000316543	psi-mi:sh3g1_rat(display_long)|uniprotkb:Endophilin-2(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 1(gene name synonym)|uniprotkb:SH3 domain protein 2B(gene name synonym)|uniprotkb:SH3p8(gene name synonym)|uniprotkb:Sh3gl1(gene name)|psi-mi:Sh3gl1(display_short)|uniprotkb:Sh3p8(gene name synonym)	psi-mi:raph1_human(display_long)|uniprotkb:RAPH1(gene name)|psi-mi:RAPH1(display_short)|uniprotkb:ALS2CR18(gene name synonym)|uniprotkb:ALS2CR9(gene name synonym)|uniprotkb:KIAA1681(gene name synonym)|uniprotkb:LPD(gene name synonym)|uniprotkb:PREL2(gene name synonym)|uniprotkb:RMO1(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 18 protein(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 9 protein(gene name synonym)|uniprotkb:Lamellipodin(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 2(gene name synonym)|uniprotkb:Protein RMO1(gene name synonym)	psi-mi:"MI:0081"(peptide array)	Vehlow et al. (2013)	imex:IM-22206|pubmed:24076656	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9149623|imex:IM-22206-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:708456|refseq:NP_112518.1|ensembl:ENSRNOG00000049683(gene)|ensembl:ENSRNOT00000074695(transcript)|go:"GO:0002102"(podosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008289"(lipid binding)|go:"GO:0016020"(membrane)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0051020"(GTPase binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|rcsb pdb:3C0C|reactome:R-RNO-182971|reactome:R-RNO-6807004|go:"GO:0017124"(SH3 domain binding)|reactome:R-RNO-8856825|reactome:R-RNO-8856828	refseq:NP_976241.1|refseq:NP_998754.1|ensembl:ENST00000308091|ensembl:ENSP00000311293|ensembl:ENSP00000316543|ensembl:ENST00000418114|ensembl:ENSP00000396711|ensembl:ENST00000419464|ensembl:ENSP00000390578|ensembl:ENST00000423104|ensembl:ENSP00000397751|ensembl:ENST00000439222|ensembl:ENSP00000411138|ensembl:ENST00000453034|ensembl:ENSP00000406662|dip:DIP-61336N|ensembl:ENSG00000173166(gene)|ensembl:ENST00000319170(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016604"(nuclear body)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0048675"(axon extension)|interpro:IPR000159(Ras-association)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR039664|interpro:IPR039665|rcsb pdb:4GMV|rcsb pdb:4GN1	-	-	-	figure legend:f3e sf2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/02/06	2014/10/16	rogid:0aG42mdp8P/MQ8GurNZiUTipVz410116	rogid:gvrXafpck5vbLuP/cmMV69yJgzs9606	intact-crc:F2619A495C0E982D|rigid:/IeBGUvdsxHrSCXHIMkjRb7oBL0	false	maltose binding protein tag:?-?|binding-associated region:312-357	binding-associated region:835-846|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0083"(peptide synthesis)
uniprotkb:O35964	uniprotkb:Q70E73	intact:EBI-1149235|ensembl:ENSRNOP00000066789	intact:EBI-3940924|uniprotkb:Q9C0I2|uniprotkb:Q96Q37|ensembl:ENSP00000316543	psi-mi:sh3g1_rat(display_long)|uniprotkb:Endophilin-2(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 1(gene name synonym)|uniprotkb:SH3 domain protein 2B(gene name synonym)|uniprotkb:SH3p8(gene name synonym)|uniprotkb:Sh3gl1(gene name)|psi-mi:Sh3gl1(display_short)|uniprotkb:Sh3p8(gene name synonym)	psi-mi:raph1_human(display_long)|uniprotkb:RAPH1(gene name)|psi-mi:RAPH1(display_short)|uniprotkb:ALS2CR18(gene name synonym)|uniprotkb:ALS2CR9(gene name synonym)|uniprotkb:KIAA1681(gene name synonym)|uniprotkb:LPD(gene name synonym)|uniprotkb:PREL2(gene name synonym)|uniprotkb:RMO1(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 18 protein(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 9 protein(gene name synonym)|uniprotkb:Lamellipodin(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 2(gene name synonym)|uniprotkb:Protein RMO1(gene name synonym)	psi-mi:"MI:0081"(peptide array)	Vehlow et al. (2013)	imex:IM-22206|pubmed:24076656	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9147776|imex:IM-22206-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:708456|refseq:NP_112518.1|ensembl:ENSRNOG00000049683(gene)|ensembl:ENSRNOT00000074695(transcript)|go:"GO:0002102"(podosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008289"(lipid binding)|go:"GO:0016020"(membrane)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0051020"(GTPase binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|rcsb pdb:3C0C|reactome:R-RNO-182971|reactome:R-RNO-6807004|go:"GO:0017124"(SH3 domain binding)|reactome:R-RNO-8856825|reactome:R-RNO-8856828	refseq:NP_976241.1|refseq:NP_998754.1|ensembl:ENST00000308091|ensembl:ENSP00000311293|ensembl:ENSP00000316543|ensembl:ENST00000418114|ensembl:ENSP00000396711|ensembl:ENST00000419464|ensembl:ENSP00000390578|ensembl:ENST00000423104|ensembl:ENSP00000397751|ensembl:ENST00000439222|ensembl:ENSP00000411138|ensembl:ENST00000453034|ensembl:ENSP00000406662|dip:DIP-61336N|ensembl:ENSG00000173166(gene)|ensembl:ENST00000319170(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016604"(nuclear body)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0048675"(axon extension)|interpro:IPR000159(Ras-association)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR039664|interpro:IPR039665|rcsb pdb:4GMV|rcsb pdb:4GN1	-	-	-	figure legend:f3e sf2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/02/06	2014/10/16	rogid:0aG42mdp8P/MQ8GurNZiUTipVz410116	rogid:gvrXafpck5vbLuP/cmMV69yJgzs9606	intact-crc:D707FBC4772B9DA5|rigid:/IeBGUvdsxHrSCXHIMkjRb7oBL0	false	maltose binding protein tag:?-?|binding-associated region:312-357	glutathione s tranferase tag:?-?|binding-associated region:682-693	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0083"(peptide synthesis)
uniprotkb:O35964	uniprotkb:Q70E73	intact:EBI-1149235|ensembl:ENSRNOP00000066789	intact:EBI-3940924|uniprotkb:Q9C0I2|uniprotkb:Q96Q37|ensembl:ENSP00000316543	psi-mi:sh3g1_rat(display_long)|uniprotkb:Endophilin-2(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 1(gene name synonym)|uniprotkb:SH3 domain protein 2B(gene name synonym)|uniprotkb:SH3p8(gene name synonym)|uniprotkb:Sh3gl1(gene name)|psi-mi:Sh3gl1(display_short)|uniprotkb:Sh3p8(gene name synonym)	psi-mi:raph1_human(display_long)|uniprotkb:RAPH1(gene name)|psi-mi:RAPH1(display_short)|uniprotkb:ALS2CR18(gene name synonym)|uniprotkb:ALS2CR9(gene name synonym)|uniprotkb:KIAA1681(gene name synonym)|uniprotkb:LPD(gene name synonym)|uniprotkb:PREL2(gene name synonym)|uniprotkb:RMO1(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 18 protein(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 9 protein(gene name synonym)|uniprotkb:Lamellipodin(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 2(gene name synonym)|uniprotkb:Protein RMO1(gene name synonym)	psi-mi:"MI:0081"(peptide array)	Vehlow et al. (2013)	imex:IM-22206|pubmed:24076656	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9151187|imex:IM-22206-22	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:708456|refseq:NP_112518.1|ensembl:ENSRNOG00000049683(gene)|ensembl:ENSRNOT00000074695(transcript)|go:"GO:0002102"(podosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008289"(lipid binding)|go:"GO:0016020"(membrane)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0051020"(GTPase binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|rcsb pdb:3C0C|reactome:R-RNO-182971|reactome:R-RNO-6807004|go:"GO:0017124"(SH3 domain binding)|reactome:R-RNO-8856825|reactome:R-RNO-8856828	refseq:NP_976241.1|refseq:NP_998754.1|ensembl:ENST00000308091|ensembl:ENSP00000311293|ensembl:ENSP00000316543|ensembl:ENST00000418114|ensembl:ENSP00000396711|ensembl:ENST00000419464|ensembl:ENSP00000390578|ensembl:ENST00000423104|ensembl:ENSP00000397751|ensembl:ENST00000439222|ensembl:ENSP00000411138|ensembl:ENST00000453034|ensembl:ENSP00000406662|dip:DIP-61336N|ensembl:ENSG00000173166(gene)|ensembl:ENST00000319170(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016604"(nuclear body)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0048675"(axon extension)|interpro:IPR000159(Ras-association)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR039664|interpro:IPR039665|rcsb pdb:4GMV|rcsb pdb:4GN1	-	-	-	figure legend:f3e sf2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/02/06	2014/10/16	rogid:0aG42mdp8P/MQ8GurNZiUTipVz410116	rogid:gvrXafpck5vbLuP/cmMV69yJgzs9606	intact-crc:C2DFD23A47CB92D5|rigid:/IeBGUvdsxHrSCXHIMkjRb7oBL0	false	maltose binding protein tag:?-?|binding-associated region:312-357	binding-associated region:1147-1158|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0083"(peptide synthesis)
uniprotkb:O35964	uniprotkb:Q70E73	intact:EBI-1149235|ensembl:ENSRNOP00000066789	intact:EBI-3940924|uniprotkb:Q9C0I2|uniprotkb:Q96Q37|ensembl:ENSP00000316543	psi-mi:sh3g1_rat(display_long)|uniprotkb:Endophilin-2(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 1(gene name synonym)|uniprotkb:SH3 domain protein 2B(gene name synonym)|uniprotkb:SH3p8(gene name synonym)|uniprotkb:Sh3gl1(gene name)|psi-mi:Sh3gl1(display_short)|uniprotkb:Sh3p8(gene name synonym)	psi-mi:raph1_human(display_long)|uniprotkb:RAPH1(gene name)|psi-mi:RAPH1(display_short)|uniprotkb:ALS2CR18(gene name synonym)|uniprotkb:ALS2CR9(gene name synonym)|uniprotkb:KIAA1681(gene name synonym)|uniprotkb:LPD(gene name synonym)|uniprotkb:PREL2(gene name synonym)|uniprotkb:RMO1(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 18 protein(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 9 protein(gene name synonym)|uniprotkb:Lamellipodin(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 2(gene name synonym)|uniprotkb:Protein RMO1(gene name synonym)	psi-mi:"MI:0081"(peptide array)	Vehlow et al. (2013)	imex:IM-22206|pubmed:24076656	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9148516|imex:IM-22206-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:708456|refseq:NP_112518.1|ensembl:ENSRNOG00000049683(gene)|ensembl:ENSRNOT00000074695(transcript)|go:"GO:0002102"(podosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008289"(lipid binding)|go:"GO:0016020"(membrane)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0051020"(GTPase binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|rcsb pdb:3C0C|reactome:R-RNO-182971|reactome:R-RNO-6807004|go:"GO:0017124"(SH3 domain binding)|reactome:R-RNO-8856825|reactome:R-RNO-8856828	refseq:NP_976241.1|refseq:NP_998754.1|ensembl:ENST00000308091|ensembl:ENSP00000311293|ensembl:ENSP00000316543|ensembl:ENST00000418114|ensembl:ENSP00000396711|ensembl:ENST00000419464|ensembl:ENSP00000390578|ensembl:ENST00000423104|ensembl:ENSP00000397751|ensembl:ENST00000439222|ensembl:ENSP00000411138|ensembl:ENST00000453034|ensembl:ENSP00000406662|dip:DIP-61336N|ensembl:ENSG00000173166(gene)|ensembl:ENST00000319170(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016604"(nuclear body)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0048675"(axon extension)|interpro:IPR000159(Ras-association)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR039664|interpro:IPR039665|rcsb pdb:4GMV|rcsb pdb:4GN1	-	-	-	figure legend:f3e sf2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/02/06	2014/10/16	rogid:0aG42mdp8P/MQ8GurNZiUTipVz410116	rogid:gvrXafpck5vbLuP/cmMV69yJgzs9606	intact-crc:D217DC7B391DF41A|rigid:/IeBGUvdsxHrSCXHIMkjRb7oBL0	false	maltose binding protein tag:?-?|binding-associated region:312-357	binding-associated region:739-750|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0083"(peptide synthesis)
uniprotkb:O35964	uniprotkb:Q70E73	intact:EBI-1149235|ensembl:ENSRNOP00000066789	intact:EBI-3940924|uniprotkb:Q9C0I2|uniprotkb:Q96Q37|ensembl:ENSP00000316543	psi-mi:sh3g1_rat(display_long)|uniprotkb:Endophilin-2(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 1(gene name synonym)|uniprotkb:SH3 domain protein 2B(gene name synonym)|uniprotkb:SH3p8(gene name synonym)|uniprotkb:Sh3gl1(gene name)|psi-mi:Sh3gl1(display_short)|uniprotkb:Sh3p8(gene name synonym)	psi-mi:raph1_human(display_long)|uniprotkb:RAPH1(gene name)|psi-mi:RAPH1(display_short)|uniprotkb:ALS2CR18(gene name synonym)|uniprotkb:ALS2CR9(gene name synonym)|uniprotkb:KIAA1681(gene name synonym)|uniprotkb:LPD(gene name synonym)|uniprotkb:PREL2(gene name synonym)|uniprotkb:RMO1(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 18 protein(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 9 protein(gene name synonym)|uniprotkb:Lamellipodin(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 2(gene name synonym)|uniprotkb:Protein RMO1(gene name synonym)	psi-mi:"MI:0081"(peptide array)	Vehlow et al. (2013)	imex:IM-22206|pubmed:24076656	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9143009|imex:IM-22206-14	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:708456|refseq:NP_112518.1|ensembl:ENSRNOG00000049683(gene)|ensembl:ENSRNOT00000074695(transcript)|go:"GO:0002102"(podosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008289"(lipid binding)|go:"GO:0016020"(membrane)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0051020"(GTPase binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|rcsb pdb:3C0C|reactome:R-RNO-182971|reactome:R-RNO-6807004|go:"GO:0017124"(SH3 domain binding)|reactome:R-RNO-8856825|reactome:R-RNO-8856828	refseq:NP_976241.1|refseq:NP_998754.1|ensembl:ENST00000308091|ensembl:ENSP00000311293|ensembl:ENSP00000316543|ensembl:ENST00000418114|ensembl:ENSP00000396711|ensembl:ENST00000419464|ensembl:ENSP00000390578|ensembl:ENST00000423104|ensembl:ENSP00000397751|ensembl:ENST00000439222|ensembl:ENSP00000411138|ensembl:ENST00000453034|ensembl:ENSP00000406662|dip:DIP-61336N|ensembl:ENSG00000173166(gene)|ensembl:ENST00000319170(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016604"(nuclear body)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0048675"(axon extension)|interpro:IPR000159(Ras-association)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR039664|interpro:IPR039665|rcsb pdb:4GMV|rcsb pdb:4GN1	-	-	-	figure legend:f3e sf2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/02/06	2014/10/16	rogid:0aG42mdp8P/MQ8GurNZiUTipVz410116	rogid:gvrXafpck5vbLuP/cmMV69yJgzs9606	intact-crc:76C55A2D7F417027|rigid:/IeBGUvdsxHrSCXHIMkjRb7oBL0	false	binding-associated region:312-357|maltose binding protein tag:?-?	binding-associated region:604-615|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0083"(peptide synthesis)
uniprotkb:O35964	uniprotkb:Q70E73	intact:EBI-1149235|ensembl:ENSRNOP00000066789	intact:EBI-3940924|uniprotkb:Q9C0I2|uniprotkb:Q96Q37|ensembl:ENSP00000316543	psi-mi:sh3g1_rat(display_long)|uniprotkb:Endophilin-2(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 1(gene name synonym)|uniprotkb:SH3 domain protein 2B(gene name synonym)|uniprotkb:SH3p8(gene name synonym)|uniprotkb:Sh3gl1(gene name)|psi-mi:Sh3gl1(display_short)|uniprotkb:Sh3p8(gene name synonym)	psi-mi:raph1_human(display_long)|uniprotkb:RAPH1(gene name)|psi-mi:RAPH1(display_short)|uniprotkb:ALS2CR18(gene name synonym)|uniprotkb:ALS2CR9(gene name synonym)|uniprotkb:KIAA1681(gene name synonym)|uniprotkb:LPD(gene name synonym)|uniprotkb:PREL2(gene name synonym)|uniprotkb:RMO1(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 18 protein(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 9 protein(gene name synonym)|uniprotkb:Lamellipodin(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 2(gene name synonym)|uniprotkb:Protein RMO1(gene name synonym)	psi-mi:"MI:0081"(peptide array)	Vehlow et al. (2013)	imex:IM-22206|pubmed:24076656	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9148023|imex:IM-22206-16	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:708456|refseq:NP_112518.1|ensembl:ENSRNOG00000049683(gene)|ensembl:ENSRNOT00000074695(transcript)|go:"GO:0002102"(podosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008289"(lipid binding)|go:"GO:0016020"(membrane)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0051020"(GTPase binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|rcsb pdb:3C0C|reactome:R-RNO-182971|reactome:R-RNO-6807004|go:"GO:0017124"(SH3 domain binding)|reactome:R-RNO-8856825|reactome:R-RNO-8856828	refseq:NP_976241.1|refseq:NP_998754.1|ensembl:ENST00000308091|ensembl:ENSP00000311293|ensembl:ENSP00000316543|ensembl:ENST00000418114|ensembl:ENSP00000396711|ensembl:ENST00000419464|ensembl:ENSP00000390578|ensembl:ENST00000423104|ensembl:ENSP00000397751|ensembl:ENST00000439222|ensembl:ENSP00000411138|ensembl:ENST00000453034|ensembl:ENSP00000406662|dip:DIP-61336N|ensembl:ENSG00000173166(gene)|ensembl:ENST00000319170(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016604"(nuclear body)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0048675"(axon extension)|interpro:IPR000159(Ras-association)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR039664|interpro:IPR039665|rcsb pdb:4GMV|rcsb pdb:4GN1	-	-	-	figure legend:f3e sf2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/02/06	2014/10/16	rogid:0aG42mdp8P/MQ8GurNZiUTipVz410116	rogid:gvrXafpck5vbLuP/cmMV69yJgzs9606	intact-crc:684D0B69CF249179|rigid:/IeBGUvdsxHrSCXHIMkjRb7oBL0	false	binding-associated region:312-357|maltose binding protein tag:?-?	glutathione s tranferase tag:?-?|binding-associated region:697-708	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0083"(peptide synthesis)
uniprotkb:O35964	uniprotkb:Q70E73	intact:EBI-1149235|ensembl:ENSRNOP00000066789	intact:EBI-3940924|uniprotkb:Q9C0I2|uniprotkb:Q96Q37|ensembl:ENSP00000316543	psi-mi:sh3g1_rat(display_long)|uniprotkb:Endophilin-2(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 1(gene name synonym)|uniprotkb:SH3 domain protein 2B(gene name synonym)|uniprotkb:SH3p8(gene name synonym)|uniprotkb:Sh3gl1(gene name)|psi-mi:Sh3gl1(display_short)|uniprotkb:Sh3p8(gene name synonym)	psi-mi:raph1_human(display_long)|uniprotkb:RAPH1(gene name)|psi-mi:RAPH1(display_short)|uniprotkb:ALS2CR18(gene name synonym)|uniprotkb:ALS2CR9(gene name synonym)|uniprotkb:KIAA1681(gene name synonym)|uniprotkb:LPD(gene name synonym)|uniprotkb:PREL2(gene name synonym)|uniprotkb:RMO1(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 18 protein(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 9 protein(gene name synonym)|uniprotkb:Lamellipodin(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 2(gene name synonym)|uniprotkb:Protein RMO1(gene name synonym)	psi-mi:"MI:0081"(peptide array)	Vehlow et al. (2013)	imex:IM-22206|pubmed:24076656	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9149107|imex:IM-22206-18	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:708456|refseq:NP_112518.1|ensembl:ENSRNOG00000049683(gene)|ensembl:ENSRNOT00000074695(transcript)|go:"GO:0002102"(podosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008289"(lipid binding)|go:"GO:0016020"(membrane)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0051020"(GTPase binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|rcsb pdb:3C0C|reactome:R-RNO-182971|reactome:R-RNO-6807004|go:"GO:0017124"(SH3 domain binding)|reactome:R-RNO-8856825|reactome:R-RNO-8856828	refseq:NP_976241.1|refseq:NP_998754.1|ensembl:ENST00000308091|ensembl:ENSP00000311293|ensembl:ENSP00000316543|ensembl:ENST00000418114|ensembl:ENSP00000396711|ensembl:ENST00000419464|ensembl:ENSP00000390578|ensembl:ENST00000423104|ensembl:ENSP00000397751|ensembl:ENST00000439222|ensembl:ENSP00000411138|ensembl:ENST00000453034|ensembl:ENSP00000406662|dip:DIP-61336N|ensembl:ENSG00000173166(gene)|ensembl:ENST00000319170(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016604"(nuclear body)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0048675"(axon extension)|interpro:IPR000159(Ras-association)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR039664|interpro:IPR039665|rcsb pdb:4GMV|rcsb pdb:4GN1	-	-	-	figure legend:f3e sf2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/02/06	2014/10/16	rogid:0aG42mdp8P/MQ8GurNZiUTipVz410116	rogid:gvrXafpck5vbLuP/cmMV69yJgzs9606	intact-crc:4426219D7D5F9249|rigid:/IeBGUvdsxHrSCXHIMkjRb7oBL0	false	binding-associated region:312-357|maltose binding protein tag:?-?	binding-associated region:772-783|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0083"(peptide synthesis)
uniprotkb:P00533	uniprotkb:Q70E73	intact:EBI-297353|uniprotkb:Q9BZS2|uniprotkb:Q9GZX1|uniprotkb:Q9H2C9|uniprotkb:Q9H3C9|uniprotkb:Q9UMD7|uniprotkb:Q9UMD8|uniprotkb:Q9UMG5|uniprotkb:O00688|uniprotkb:O00732|uniprotkb:P06268|uniprotkb:Q14225|uniprotkb:Q92795|intact:EBI-28985169|ensembl:ENSP00000275493|uniprotkb:Q68GS5	intact:EBI-3940924|uniprotkb:Q9C0I2|uniprotkb:Q96Q37|ensembl:ENSP00000316543	psi-mi:egfr_human(display_long)|uniprotkb:ERBB1(gene name synonym)|uniprotkb:EGFR(gene name)|psi-mi:EGFR(display_short)|uniprotkb:Receptor tyrosine-protein kinase erbB-1(gene name synonym)|uniprotkb:Proto-oncogene c-ErbB-1(gene name synonym)|uniprotkb:ERBB(gene name synonym)|uniprotkb:HER1(gene name synonym)	psi-mi:raph1_human(display_long)|uniprotkb:RAPH1(gene name)|psi-mi:RAPH1(display_short)|uniprotkb:ALS2CR18(gene name synonym)|uniprotkb:ALS2CR9(gene name synonym)|uniprotkb:KIAA1681(gene name synonym)|uniprotkb:LPD(gene name synonym)|uniprotkb:PREL2(gene name synonym)|uniprotkb:RMO1(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 18 protein(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 9 protein(gene name synonym)|uniprotkb:Lamellipodin(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 2(gene name synonym)|uniprotkb:Protein RMO1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Vehlow et al. (2013)	imex:IM-22206|pubmed:24076656	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9160561|imex:IM-22206-25	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000146648(gene)|ensembl:ENST00000275493(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001503"(ossification)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001942"(hair follicle development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005006"(epidermal growth factor-activated receptor activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0007494"(midgut development)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035690"|go:"GO:0007611"(learning or memory)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033590"(response to cobalamin)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042311"(vasodilation)|go:"GO:0033594"(response to hydroxyisoflavone)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042698"(ovulation cycle)|go:"GO:0042743"(hydrogen peroxide metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043006"(activation of phospholipase A2 activity by calcium-mediated signaling)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043235"(receptor complex)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043586"(tongue development)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010750"(positive regulation of nitric oxide mediated signal transduction)|go:"GO:0010960"(magnesium ion homeostasis)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016101"(diterpenoid metabolic process)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030154"(cell differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030324"(lung development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032930"(positive regulation of superoxide anion generation)|rcsb pdb:4WD5|rcsb pdb:4WKQ|rcsb pdb:4WRG|rcsb pdb:4ZAU|rcsb pdb:4ZJV|rcsb pdb:4ZSE|rcsb pdb:5C8K|rcsb pdb:5C8M|rcsb pdb:5C8N|rcsb pdb:5CAL|rcsb pdb:5CAN|rcsb pdb:5CAO|rcsb pdb:5CAP|rcsb pdb:5CAQ|rcsb pdb:4UV7|rcsb pdb:5CAS|rcsb pdb:5CAU|rcsb pdb:5CAV|rcsb pdb:5CNN|rcsb pdb:5CNO|rcsb pdb:5CZH|rcsb pdb:5CZI|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048143"(astrocyte activation)|go:"GO:0048408"(epidermal growth factor binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050999"(regulation of nitric-oxide synthase activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051205"(protein insertion into membrane)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|rcsb pdb:5UGB|rcsb pdb:5UGC|rcsb pdb:5UWD|rcsb pdb:5WB7|rcsb pdb:5WB8|rcsb pdb:5X26|rcsb pdb:5X27|rcsb pdb:5X28|rcsb pdb:5X2A|rcsb pdb:5X2C|rcsb pdb:5X2F|rcsb pdb:5X2K|rcsb pdb:5XDK|rcsb pdb:5XDL|rcsb pdb:5XGM|rcsb pdb:5XGN|rcsb pdb:5XWD|rcsb pdb:5Y25|rcsb pdb:5Y9T|rcsb pdb:5YU9|rcsb pdb:5ZTO|rcsb pdb:5ZWJ|rcsb pdb:6ARU|rcsb pdb:6B3S|rcsb pdb:5D41|rcsb pdb:6D8E|rcsb pdb:6DUK|rcsb pdb:6JRJ|rcsb pdb:6JRK|rcsb pdb:6JRX|rcsb pdb:6JWL|rcsb pdb:6JX0|rcsb pdb:6JX4|rcsb pdb:6JXT|rcsb pdb:6JZ0|go:"GO:0097489"(multivesicular body, internal vesicle lumen)|go:"GO:0097708"(intracellular vesicle)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900020"(positive regulation of protein kinase C activity)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902722"(positive regulation of prolactin secretion)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1905208"(negative regulation of cardiocyte differentiation)|interpro:IPR000494(EGF receptor, L domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR006211(Furin-like cysteine rich region)|interpro:IPR006212(Furin-like repeat)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR009030(Growth factor, receptor)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0070141"(response to UV-A)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070435"(Shc-EGFR complex)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097421"(liver regeneration)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016245(Tyrosine protein kinase, receptor-type, EGF/ERB/XmrK)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR032778|interpro:IPR036941|mint:P00533|rcsb pdb:1DNQ|rcsb pdb:1DNR|rcsb pdb:1IVO|rcsb pdb:1M14|rcsb pdb:1M17|rcsb pdb:1MOX|rcsb pdb:1NQL|rcsb pdb:1XKK|rcsb pdb:1YY9|rcsb pdb:1Z9I|rcsb pdb:2EB2|rcsb pdb:2EB3|rcsb pdb:2EXP|rcsb pdb:2EXQ|rcsb pdb:2GS2|rcsb pdb:2GS6|rcsb pdb:2J5E|rcsb pdb:2J5F|rcsb pdb:2GS7|rcsb pdb:2J6M|rcsb pdb:2JIT|rcsb pdb:2ITN|rcsb pdb:2JIU|rcsb pdb:2ITO|rcsb pdb:2JIV|rcsb pdb:2KS1|rcsb pdb:2ITP|rcsb pdb:2M0B|rcsb pdb:2M20|rcsb pdb:2ITQ|rcsb pdb:2N5S|rcsb pdb:2RF9|rcsb pdb:2RFD|rcsb pdb:2RFE|rcsb pdb:2RGP|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BEL|rcsb pdb:2ITT|rcsb pdb:3BUO|rcsb pdb:3C09|rcsb pdb:3G5V|rcsb pdb:3G5Y|rcsb pdb:3GOP|rcsb pdb:3GT8|rcsb pdb:3IKA|rcsb pdb:3LZB|rcsb pdb:2ITU|rcsb pdb:3NJP|rcsb pdb:3OB2|rcsb pdb:2ITV|rcsb pdb:3OP0|rcsb pdb:2ITW|rcsb pdb:2ITX|rcsb pdb:2ITY|rcsb pdb:3P0Y|rcsb pdb:2ITZ|rcsb pdb:3PFV|rcsb pdb:3POZ|rcsb pdb:3QWQ|rcsb pdb:3UG1|rcsb pdb:3UG2|rcsb pdb:3VJN|rcsb pdb:3VJO|rcsb pdb:3VRP|rcsb pdb:3VRR|rcsb pdb:5EM7|rcsb pdb:5EM8|rcsb pdb:5FED|rcsb pdb:5FEE|rcsb pdb:5FEQ|rcsb pdb:5GMP|rcsb pdb:5GNK|rcsb pdb:5GTY|rcsb pdb:5GTZ|rcsb pdb:5HCX|rcsb pdb:5HCY|rcsb pdb:5HCZ|rcsb pdb:5HG5|rcsb pdb:5HG7|rcsb pdb:5HG8|rcsb pdb:5HG9|rcsb pdb:5HIB|rcsb pdb:5HIC|rcsb pdb:5EDP|rcsb pdb:5J9Y|rcsb pdb:5J9Z|rcsb pdb:5JEB|rcsb pdb:5LV6|rcsb pdb:5SX4|rcsb pdb:5EDQ|rcsb pdb:5EDR|rcsb pdb:5EM5|rcsb pdb:5SX5|rcsb pdb:5U8L|rcsb pdb:5UG8|rcsb pdb:5EM6|rcsb pdb:5UG9|rcsb pdb:5UGA|rcsb pdb:3W2O|rcsb pdb:4JR3|rcsb pdb:3W2P|rcsb pdb:3W2Q|rcsb pdb:4JRV|rcsb pdb:4KRL|rcsb pdb:4KRM|rcsb pdb:4KRO|rcsb pdb:3W2R|rcsb pdb:4KRP|rcsb pdb:4LI5|rcsb pdb:4LL0|rcsb pdb:3W2S|rcsb pdb:4LQM|rcsb pdb:4LRM|rcsb pdb:3W32|rcsb pdb:4R3P|rcsb pdb:4R3R|rcsb pdb:4R5S|rcsb pdb:3W33|rcsb pdb:4RIW|rcsb pdb:4G5J|rcsb pdb:4RIX|rcsb pdb:4G5P|rcsb pdb:4RIY|rcsb pdb:4RJ4|rcsb pdb:4RJ5|rcsb pdb:4HJO|rcsb pdb:4I1Z|rcsb pdb:4I20|rcsb pdb:4I21|rcsb pdb:4I22|rcsb pdb:4I23|rcsb pdb:4I24|rcsb pdb:4JQ7|rcsb pdb:4JQ8|rcsb pdb:4RJ6|rcsb pdb:4RJ7|rcsb pdb:4RJ8|rcsb pdb:4TKS|rcsb pdb:4UIP|rcsb pdb:6LUD|rcsb pdb:6P1D|rcsb pdb:6P1L|rcsb pdb:6P8Q|rcsb pdb:6S89|rcsb pdb:6S8A|rcsb pdb:6S9B|rcsb pdb:6S9C|rcsb pdb:6S9D|rcsb pdb:6TFU|rcsb pdb:6LUB|rcsb pdb:6TFV|rcsb pdb:6TFW|rcsb pdb:6TFY|rcsb pdb:6TFZ|rcsb pdb:6TG0|rcsb pdb:6TG1|rcsb pdb:6V5N|rcsb pdb:6V5P|rcsb pdb:6V66|rcsb pdb:6V6K|rcsb pdb:6V6O|rcsb pdb:6VH4|rcsb pdb:6VHN|rcsb pdb:6VHP|rcsb pdb:6WA2|rcsb pdb:6WAK|rcsb pdb:6WXN|rcsb pdb:6XL4|rcsb pdb:6Z4B|rcsb pdb:6Z4D|rcsb pdb:7A2A|rcsb pdb:7AEI|rcsb pdb:7AEM|reactome:R-HSA-1227986|reactome:R-HSA-1236382|reactome:R-HSA-1236394|reactome:R-HSA-1250196|reactome:R-HSA-1251932|reactome:R-HSA-1257604|reactome:R-HSA-177929|reactome:R-HSA-180292|reactome:R-HSA-180336|reactome:R-HSA-182971|reactome:R-HSA-1963640|reactome:R-HSA-1963642|reactome:R-HSA-212718|reactome:R-HSA-2179392|reactome:R-HSA-2219530|reactome:R-HSA-445144|reactome:R-HSA-5637810|reactome:R-HSA-5638303|reactome:R-HSA-5673001|reactome:R-HSA-6785631|reactome:R-HSA-6811558|reactome:R-HSA-8847993|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-179812|reactome:R-HSA-8857538|reactome:R-HSA-8863795|reactome:R-HSA-9009391|reactome:R-HSA-9013507|reactome:R-HSA-9609690|reactome:R-HSA-9634638|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-8866910|refseq:NP_005219.2|refseq:NP_958439.1|refseq:NP_958440.1|refseq:NP_958441.1|ensembl:ENSP00000275493|ensembl:ENST00000342916|ensembl:ENSP00000342376|ensembl:ENST00000344576|ensembl:ENSP00000345973|ensembl:ENST00000420316|ensembl:ENSP00000413843|dip:DIP-405N	refseq:NP_976241.1|refseq:NP_998754.1|ensembl:ENST00000308091|ensembl:ENSP00000311293|ensembl:ENSP00000316543|ensembl:ENST00000418114|ensembl:ENSP00000396711|ensembl:ENST00000419464|ensembl:ENSP00000390578|ensembl:ENST00000423104|ensembl:ENSP00000397751|ensembl:ENST00000439222|ensembl:ENSP00000411138|ensembl:ENST00000453034|ensembl:ENSP00000406662|dip:DIP-61336N|ensembl:ENSG00000173166(gene)|ensembl:ENST00000319170(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016604"(nuclear body)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0048675"(axon extension)|interpro:IPR000159(Ras-association)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR039664|interpro:IPR039665|rcsb pdb:4GMV|rcsb pdb:4GN1	-	-	-	figure legend:f4d|comment:"We also observed co‐immunoprecipitation of endogenous Lpd and EGFR in A431 (Figure 4C and D) and in HeLa cells (Figure 4E and F), which suggests that the actin cytoskeletal regulator Lpd and the EGFR form a protein complex in cells."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_431)|taxid:9606(Homo sapiens epidermoid carcinoma)	-	2014/02/06	2014/10/16	rogid:gXB5slVTC+z8DdqqXIzXG7lDwk09606	rogid:gvrXafpck5vbLuP/cmMV69yJgzs9606	intact-crc:805E988AB5362E9D|rigid:1cHLCUimkX8MALJN2BzPVFYDuhs	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q70E73	uniprotkb:P00533	intact:EBI-3940924|uniprotkb:Q9C0I2|uniprotkb:Q96Q37|ensembl:ENSP00000316543	intact:EBI-297353|uniprotkb:Q9BZS2|uniprotkb:Q9GZX1|uniprotkb:Q9H2C9|uniprotkb:Q9H3C9|uniprotkb:Q9UMD7|uniprotkb:Q9UMD8|uniprotkb:Q9UMG5|uniprotkb:O00688|uniprotkb:O00732|uniprotkb:P06268|uniprotkb:Q14225|uniprotkb:Q92795|intact:EBI-28985169|ensembl:ENSP00000275493|uniprotkb:Q68GS5	psi-mi:raph1_human(display_long)|uniprotkb:RAPH1(gene name)|psi-mi:RAPH1(display_short)|uniprotkb:ALS2CR18(gene name synonym)|uniprotkb:ALS2CR9(gene name synonym)|uniprotkb:KIAA1681(gene name synonym)|uniprotkb:LPD(gene name synonym)|uniprotkb:PREL2(gene name synonym)|uniprotkb:RMO1(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 18 protein(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 9 protein(gene name synonym)|uniprotkb:Lamellipodin(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 2(gene name synonym)|uniprotkb:Protein RMO1(gene name synonym)	psi-mi:egfr_human(display_long)|uniprotkb:ERBB1(gene name synonym)|uniprotkb:EGFR(gene name)|psi-mi:EGFR(display_short)|uniprotkb:Receptor tyrosine-protein kinase erbB-1(gene name synonym)|uniprotkb:Proto-oncogene c-ErbB-1(gene name synonym)|uniprotkb:ERBB(gene name synonym)|uniprotkb:HER1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Vehlow et al. (2013)	imex:IM-22206|pubmed:24076656	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9160551|imex:IM-22206-24	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_976241.1|refseq:NP_998754.1|ensembl:ENST00000308091|ensembl:ENSP00000311293|ensembl:ENSP00000316543|ensembl:ENST00000418114|ensembl:ENSP00000396711|ensembl:ENST00000419464|ensembl:ENSP00000390578|ensembl:ENST00000423104|ensembl:ENSP00000397751|ensembl:ENST00000439222|ensembl:ENSP00000411138|ensembl:ENST00000453034|ensembl:ENSP00000406662|dip:DIP-61336N|ensembl:ENSG00000173166(gene)|ensembl:ENST00000319170(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016604"(nuclear body)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0048675"(axon extension)|interpro:IPR000159(Ras-association)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR039664|interpro:IPR039665|rcsb pdb:4GMV|rcsb pdb:4GN1	ensembl:ENSG00000146648(gene)|ensembl:ENST00000275493(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001503"(ossification)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001942"(hair follicle development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005006"(epidermal growth factor-activated receptor activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0007494"(midgut development)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035690"|go:"GO:0007611"(learning or memory)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033590"(response to cobalamin)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042311"(vasodilation)|go:"GO:0033594"(response to hydroxyisoflavone)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042698"(ovulation cycle)|go:"GO:0042743"(hydrogen peroxide metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043006"(activation of phospholipase A2 activity by calcium-mediated signaling)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043235"(receptor complex)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043586"(tongue development)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010750"(positive regulation of nitric oxide mediated signal transduction)|go:"GO:0010960"(magnesium ion homeostasis)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016101"(diterpenoid metabolic process)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030154"(cell differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030324"(lung development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032930"(positive regulation of superoxide anion generation)|rcsb pdb:4WD5|rcsb pdb:4WKQ|rcsb pdb:4WRG|rcsb pdb:4ZAU|rcsb pdb:4ZJV|rcsb pdb:4ZSE|rcsb pdb:5C8K|rcsb pdb:5C8M|rcsb pdb:5C8N|rcsb pdb:5CAL|rcsb pdb:5CAN|rcsb pdb:5CAO|rcsb pdb:5CAP|rcsb pdb:5CAQ|rcsb pdb:4UV7|rcsb pdb:5CAS|rcsb pdb:5CAU|rcsb pdb:5CAV|rcsb pdb:5CNN|rcsb pdb:5CNO|rcsb pdb:5CZH|rcsb pdb:5CZI|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048143"(astrocyte activation)|go:"GO:0048408"(epidermal growth factor binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050999"(regulation of nitric-oxide synthase activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051205"(protein insertion into membrane)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|rcsb pdb:5UGB|rcsb pdb:5UGC|rcsb pdb:5UWD|rcsb pdb:5WB7|rcsb pdb:5WB8|rcsb pdb:5X26|rcsb pdb:5X27|rcsb pdb:5X28|rcsb pdb:5X2A|rcsb pdb:5X2C|rcsb pdb:5X2F|rcsb pdb:5X2K|rcsb pdb:5XDK|rcsb pdb:5XDL|rcsb pdb:5XGM|rcsb pdb:5XGN|rcsb pdb:5XWD|rcsb pdb:5Y25|rcsb pdb:5Y9T|rcsb pdb:5YU9|rcsb pdb:5ZTO|rcsb pdb:5ZWJ|rcsb pdb:6ARU|rcsb pdb:6B3S|rcsb pdb:5D41|rcsb pdb:6D8E|rcsb pdb:6DUK|rcsb pdb:6JRJ|rcsb pdb:6JRK|rcsb pdb:6JRX|rcsb pdb:6JWL|rcsb pdb:6JX0|rcsb pdb:6JX4|rcsb pdb:6JXT|rcsb pdb:6JZ0|go:"GO:0097489"(multivesicular body, internal vesicle lumen)|go:"GO:0097708"(intracellular vesicle)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900020"(positive regulation of protein kinase C activity)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902722"(positive regulation of prolactin secretion)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1905208"(negative regulation of cardiocyte differentiation)|interpro:IPR000494(EGF receptor, L domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR006211(Furin-like cysteine rich region)|interpro:IPR006212(Furin-like repeat)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR009030(Growth factor, receptor)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0070141"(response to UV-A)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070435"(Shc-EGFR complex)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097421"(liver regeneration)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016245(Tyrosine protein kinase, receptor-type, EGF/ERB/XmrK)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR032778|interpro:IPR036941|mint:P00533|rcsb pdb:1DNQ|rcsb pdb:1DNR|rcsb pdb:1IVO|rcsb pdb:1M14|rcsb pdb:1M17|rcsb pdb:1MOX|rcsb pdb:1NQL|rcsb pdb:1XKK|rcsb pdb:1YY9|rcsb pdb:1Z9I|rcsb pdb:2EB2|rcsb pdb:2EB3|rcsb pdb:2EXP|rcsb pdb:2EXQ|rcsb pdb:2GS2|rcsb pdb:2GS6|rcsb pdb:2J5E|rcsb pdb:2J5F|rcsb pdb:2GS7|rcsb pdb:2J6M|rcsb pdb:2JIT|rcsb pdb:2ITN|rcsb pdb:2JIU|rcsb pdb:2ITO|rcsb pdb:2JIV|rcsb pdb:2KS1|rcsb pdb:2ITP|rcsb pdb:2M0B|rcsb pdb:2M20|rcsb pdb:2ITQ|rcsb pdb:2N5S|rcsb pdb:2RF9|rcsb pdb:2RFD|rcsb pdb:2RFE|rcsb pdb:2RGP|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BEL|rcsb pdb:2ITT|rcsb pdb:3BUO|rcsb pdb:3C09|rcsb pdb:3G5V|rcsb pdb:3G5Y|rcsb pdb:3GOP|rcsb pdb:3GT8|rcsb pdb:3IKA|rcsb pdb:3LZB|rcsb pdb:2ITU|rcsb pdb:3NJP|rcsb pdb:3OB2|rcsb pdb:2ITV|rcsb pdb:3OP0|rcsb pdb:2ITW|rcsb pdb:2ITX|rcsb pdb:2ITY|rcsb pdb:3P0Y|rcsb pdb:2ITZ|rcsb pdb:3PFV|rcsb pdb:3POZ|rcsb pdb:3QWQ|rcsb pdb:3UG1|rcsb pdb:3UG2|rcsb pdb:3VJN|rcsb pdb:3VJO|rcsb pdb:3VRP|rcsb pdb:3VRR|rcsb pdb:5EM7|rcsb pdb:5EM8|rcsb pdb:5FED|rcsb pdb:5FEE|rcsb pdb:5FEQ|rcsb pdb:5GMP|rcsb pdb:5GNK|rcsb pdb:5GTY|rcsb pdb:5GTZ|rcsb pdb:5HCX|rcsb pdb:5HCY|rcsb pdb:5HCZ|rcsb pdb:5HG5|rcsb pdb:5HG7|rcsb pdb:5HG8|rcsb pdb:5HG9|rcsb pdb:5HIB|rcsb pdb:5HIC|rcsb pdb:5EDP|rcsb pdb:5J9Y|rcsb pdb:5J9Z|rcsb pdb:5JEB|rcsb pdb:5LV6|rcsb pdb:5SX4|rcsb pdb:5EDQ|rcsb pdb:5EDR|rcsb pdb:5EM5|rcsb pdb:5SX5|rcsb pdb:5U8L|rcsb pdb:5UG8|rcsb pdb:5EM6|rcsb pdb:5UG9|rcsb pdb:5UGA|rcsb pdb:3W2O|rcsb pdb:4JR3|rcsb pdb:3W2P|rcsb pdb:3W2Q|rcsb pdb:4JRV|rcsb pdb:4KRL|rcsb pdb:4KRM|rcsb pdb:4KRO|rcsb pdb:3W2R|rcsb pdb:4KRP|rcsb pdb:4LI5|rcsb pdb:4LL0|rcsb pdb:3W2S|rcsb pdb:4LQM|rcsb pdb:4LRM|rcsb pdb:3W32|rcsb pdb:4R3P|rcsb pdb:4R3R|rcsb pdb:4R5S|rcsb pdb:3W33|rcsb pdb:4RIW|rcsb pdb:4G5J|rcsb pdb:4RIX|rcsb pdb:4G5P|rcsb pdb:4RIY|rcsb pdb:4RJ4|rcsb pdb:4RJ5|rcsb pdb:4HJO|rcsb pdb:4I1Z|rcsb pdb:4I20|rcsb pdb:4I21|rcsb pdb:4I22|rcsb pdb:4I23|rcsb pdb:4I24|rcsb pdb:4JQ7|rcsb pdb:4JQ8|rcsb pdb:4RJ6|rcsb pdb:4RJ7|rcsb pdb:4RJ8|rcsb pdb:4TKS|rcsb pdb:4UIP|rcsb pdb:6LUD|rcsb pdb:6P1D|rcsb pdb:6P1L|rcsb pdb:6P8Q|rcsb pdb:6S89|rcsb pdb:6S8A|rcsb pdb:6S9B|rcsb pdb:6S9C|rcsb pdb:6S9D|rcsb pdb:6TFU|rcsb pdb:6LUB|rcsb pdb:6TFV|rcsb pdb:6TFW|rcsb pdb:6TFY|rcsb pdb:6TFZ|rcsb pdb:6TG0|rcsb pdb:6TG1|rcsb pdb:6V5N|rcsb pdb:6V5P|rcsb pdb:6V66|rcsb pdb:6V6K|rcsb pdb:6V6O|rcsb pdb:6VH4|rcsb pdb:6VHN|rcsb pdb:6VHP|rcsb pdb:6WA2|rcsb pdb:6WAK|rcsb pdb:6WXN|rcsb pdb:6XL4|rcsb pdb:6Z4B|rcsb pdb:6Z4D|rcsb pdb:7A2A|rcsb pdb:7AEI|rcsb pdb:7AEM|reactome:R-HSA-1227986|reactome:R-HSA-1236382|reactome:R-HSA-1236394|reactome:R-HSA-1250196|reactome:R-HSA-1251932|reactome:R-HSA-1257604|reactome:R-HSA-177929|reactome:R-HSA-180292|reactome:R-HSA-180336|reactome:R-HSA-182971|reactome:R-HSA-1963640|reactome:R-HSA-1963642|reactome:R-HSA-212718|reactome:R-HSA-2179392|reactome:R-HSA-2219530|reactome:R-HSA-445144|reactome:R-HSA-5637810|reactome:R-HSA-5638303|reactome:R-HSA-5673001|reactome:R-HSA-6785631|reactome:R-HSA-6811558|reactome:R-HSA-8847993|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-179812|reactome:R-HSA-8857538|reactome:R-HSA-8863795|reactome:R-HSA-9009391|reactome:R-HSA-9013507|reactome:R-HSA-9609690|reactome:R-HSA-9634638|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-8866910|refseq:NP_005219.2|refseq:NP_958439.1|refseq:NP_958440.1|refseq:NP_958441.1|ensembl:ENSP00000275493|ensembl:ENST00000342916|ensembl:ENSP00000342376|ensembl:ENST00000344576|ensembl:ENSP00000345973|ensembl:ENST00000420316|ensembl:ENSP00000413843|dip:DIP-405N	-	-	-	figure legend:f4c|comment:"We also observed co‐immunoprecipitation of endogenous Lpd and EGFR in A431 (Figure 4C and D) and in HeLa cells (Figure 4E and F), which suggests that the actin cytoskeletal regulator Lpd and the EGFR form a protein complex in cells."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_431)|taxid:9606(Homo sapiens epidermoid carcinoma)	-	2014/02/06	2014/10/16	rogid:gvrXafpck5vbLuP/cmMV69yJgzs9606	rogid:gXB5slVTC+z8DdqqXIzXG7lDwk09606	intact-crc:92D0D41B875C6F3E|rigid:1cHLCUimkX8MALJN2BzPVFYDuhs	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)