#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P43583 uniprotkb:Q03790 intact:EBI-22761|uniprotkb:D6VTM3|uniprotkb:P43584|ensemblfungi:YFL007W intact:EBI-27321|uniprotkb:D6VZX4|ensemblfungi:YMR153W psi-mi:blm10_yeast(display_long)|uniprotkb:YFL006W(orf name)|uniprotkb:YFL007W(locus name)|uniprotkb:BLM3(gene name synonym)|uniprotkb:BLM10(gene name)|psi-mi:BLM10(display_short)|uniprotkb:Bleomycin resistance protein BLM10(gene name synonym) psi-mi:nup53_yeast(display_long)|uniprotkb:Nuclear pore protein NUP53(gene name synonym)|uniprotkb:NUP53(gene name)|psi-mi:NUP53(display_short)|uniprotkb:YMR153W(locus name)|uniprotkb:YM8520.02(orf name) psi-mi:"MI:0096"(pull down) Weberruss et al. (2013) pubmed:23982732|imex:IM-22094 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-9117313|imex:IM-22094-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YFL007W(gene)|ensemblfungi:YFL007W_mRNA(transcript)|refseq:NP_116648.2|sgd:S000001887|dip:DIP-6344N|mint:P43583|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0043248"(proteasome assembly)|go:"GO:0043486"(histone exchange)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:1902906"(proteasome storage granule assembly)|go:"GO:1990236"(proteasome core complex import into nucleus)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021843|interpro:IPR032372|interpro:IPR032430|interpro:IPR035309|rcsb pdb:4V7O|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168 refseq:NP_013873.1|sgd:S000004762|dip:DIP-1467N|ensemblfungi:YMR153W(gene)|ensemblfungi:YMR153W_mRNA(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|go:"GO:0060188"(regulation of protein desumoylation)|go:"GO:0072417"(response to spindle checkpoint signaling)|interpro:IPR007846(MPPN)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017389(Nucleoporin, NUP53)|interpro:IPR035979|rcsb pdb:3W3Y|rcsb pdb:5UAZ - crc64:A195A4455C687644 crc64:2ECE0C561D27E523 figure legend:f4d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/02/04 2014/10/16 rogid:wOg3ZjlWLKBTVKFVD8w7+tUyJF8559292 rogid:csq2oRFswkgY2JkT+dmz/L7Zpfk559292 intact-crc:18E5845032C771A5|rigid:H6ZfwJJR0dDomQolD+9/o4fulYY false his tag:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P43583 uniprotkb:P32835 intact:EBI-22761|uniprotkb:D6VTM3|uniprotkb:P43584|ensemblfungi:YFL007W intact:EBI-7926|uniprotkb:D6VYT9|ensemblfungi:YLR293C psi-mi:blm10_yeast(display_long)|uniprotkb:YFL006W(orf name)|uniprotkb:YFL007W(locus name)|uniprotkb:BLM3(gene name synonym)|uniprotkb:BLM10(gene name)|psi-mi:BLM10(display_short)|uniprotkb:Bleomycin resistance protein BLM10(gene name synonym) psi-mi:gsp1_yeast(display_long)|uniprotkb:CNR1(gene name synonym)|uniprotkb:CST17(gene name synonym)|uniprotkb:GTPase Ran homolog(gene name synonym)|uniprotkb:L8003.19(orf name)|uniprotkb:YLR293C(locus name)|uniprotkb:GSP1(gene name)|psi-mi:GSP1(display_short)|uniprotkb:Genetic suppressor of PRP20-1(gene name synonym)|uniprotkb:Chromosome stability protein 17(gene name synonym) psi-mi:"MI:0096"(pull down) Weberruss et al. (2013) pubmed:23982732|imex:IM-22094 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-9117300|imex:IM-22094-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YFL007W(gene)|ensemblfungi:YFL007W_mRNA(transcript)|refseq:NP_116648.2|sgd:S000001887|dip:DIP-6344N|mint:P43583|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0043248"(proteasome assembly)|go:"GO:0043486"(histone exchange)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:1902906"(proteasome storage granule assembly)|go:"GO:1990236"(proteasome core complex import into nucleus)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021843|interpro:IPR032372|interpro:IPR032430|interpro:IPR035309|rcsb pdb:4V7O|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168 refseq:NP_013396.1|sgd:S000004284|mint:P32835|dip:DIP-747N|ensemblfungi:YLR293C(gene)|ensemblfungi:YLR293C_mRNA(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:1901987"(regulation of cell cycle phase transition)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:2X19|rcsb pdb:3ICQ|rcsb pdb:3M1I|rcsb pdb:3WYG|reactome:R-SCE-9615933 - crc64:A195A4455C687644 crc64:C9D027033F8C70E1 figure legend:f4b f4c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/02/04 2014/10/16 rogid:wOg3ZjlWLKBTVKFVD8w7+tUyJF8559292 rogid:1sewGL113s4tIFXpHVw2rtBUg/A559292 intact-crc:64C8ABC6B4A02450|rigid:mzKF+xiYGB7lVDZV9ABDVc9GH+o false his tag:?-?|sufficient binding region:1804-2143|mutation disrupting interaction:2021-2021 glutathione s tranferase tag:?-?|mutation increasing interaction:71-71 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P43583 uniprotkb:P32835 intact:EBI-22761|uniprotkb:D6VTM3|uniprotkb:P43584|ensemblfungi:YFL007W intact:EBI-7926|uniprotkb:D6VYT9|ensemblfungi:YLR293C psi-mi:blm10_yeast(display_long)|uniprotkb:YFL006W(orf name)|uniprotkb:YFL007W(locus name)|uniprotkb:BLM3(gene name synonym)|uniprotkb:BLM10(gene name)|psi-mi:BLM10(display_short)|uniprotkb:Bleomycin resistance protein BLM10(gene name synonym) psi-mi:gsp1_yeast(display_long)|uniprotkb:CNR1(gene name synonym)|uniprotkb:CST17(gene name synonym)|uniprotkb:GTPase Ran homolog(gene name synonym)|uniprotkb:L8003.19(orf name)|uniprotkb:YLR293C(locus name)|uniprotkb:GSP1(gene name)|psi-mi:GSP1(display_short)|uniprotkb:Genetic suppressor of PRP20-1(gene name synonym)|uniprotkb:Chromosome stability protein 17(gene name synonym) psi-mi:"MI:0276"(blue native page) Weberruss et al. (2013) pubmed:23982732|imex:IM-22094 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-9117369|imex:IM-22094-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YFL007W(gene)|ensemblfungi:YFL007W_mRNA(transcript)|refseq:NP_116648.2|sgd:S000001887|dip:DIP-6344N|mint:P43583|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0043248"(proteasome assembly)|go:"GO:0043486"(histone exchange)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070628"(proteasome binding)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:1902906"(proteasome storage granule assembly)|go:"GO:1990236"(proteasome core complex import into nucleus)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021843|interpro:IPR032372|interpro:IPR032430|interpro:IPR035309|rcsb pdb:4V7O|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168 refseq:NP_013396.1|sgd:S000004284|mint:P32835|dip:DIP-747N|ensemblfungi:YLR293C(gene)|ensemblfungi:YLR293C_mRNA(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:1901987"(regulation of cell cycle phase transition)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:2X19|rcsb pdb:3ICQ|rcsb pdb:3M1I|rcsb pdb:3WYG|reactome:R-SCE-9615933 - crc64:A195A4455C687644 crc64:C9D027033F8C70E1 figure legend:f4g|comment:"Native PAGE and fluoroimaging revealed that Blm10 was ejected from the CP by Gsp1‐GTP as indicated by the gel shift towards the fast‐migrating CP species. Gsp1 (molecular mass of 25 kDa) and Blm10 (240 kDa) co‐migrated in native PAGE as shown by western blotting against Blm10 and Gsp1 allowing the conclusion that Blm10 and Gsp1 associate in solution (Figure 4G)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/02/04 2014/10/16 rogid:wOg3ZjlWLKBTVKFVD8w7+tUyJF8559292 rogid:1sewGL113s4tIFXpHVw2rtBUg/A559292 intact-crc:62FF446D9BAEBE1D|rigid:mzKF+xiYGB7lVDZV9ABDVc9GH+o false his tag:?-? - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot)