#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P08645 uniprotkb:Q9VAS8 intact:EBI-175963|uniprotkb:Q2XYB6|uniprotkb:Q540V3|uniprotkb:Q9V3N0|ensemblmetazoa:FBpp0072746|ensemblmetazoa:FBpp0292253|ensemblmetazoa:FBpp0304917 intact:EBI-118084|ensemblmetazoa:FBpp0303336 psi-mi:rap1_drome(display_long)|uniprotkb:Rap1(gene name)|psi-mi:Rap1(display_short)|uniprotkb:R(gene name synonym)|uniprotkb:RAP(gene name synonym)|uniprotkb:Rap1 GTPase(gene name synonym)|uniprotkb:Ras-like protein 3(gene name synonym)|uniprotkb:ras3(gene name synonym)|uniprotkb:CG1956(orf name) psi-mi:q9vas8_drome(display_long)|uniprotkb:spg(gene name)|psi-mi:spg(display_short)|uniprotkb:CG31048(orf name)|uniprotkb:CG11754(gene name synonym)|uniprotkb:CG14530(gene name synonym)|uniprotkb:Dm Dock4(gene name synonym)|uniprotkb:Dmel\CG31048(gene name synonym)|uniprotkb:Spg(gene name synonym)|uniprotkb:"mat(3)6"(gene name synonym)|uniprotkb:"mat3(6)"(gene name synonym)|uniprotkb:Dmel_CG31048(orf name) psi-mi:"MI:0813"(proximity ligation assay) Eguchi et al. (2013) imex:IM-23079|pubmed:23747680 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:2364"(proximity) psi-mi:"MI:0469"(IntAct) intact:EBI-9700741|imex:IM-23079-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001189023.1|refseq:NP_476857.1|flybase:FBgn0004636|refseq:NP_001261295.1|ensemblmetazoa:FBgn0004636(gene)|ensemblmetazoa:FBtr0072867(transcript)|ensemblmetazoa:FBtr0303154(transcript)|ensemblmetazoa:FBtr0332671(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007391"(dorsal closure)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007601"(visual perception)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031252"(cell leading edge)|go:"GO:0032486"(Rap protein signal transduction)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035099"(hemocyte migration)|go:"GO:0035317"(imaginal disc-derived wing hair organization)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0045874"(positive regulation of sevenless signaling pathway)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:2000301"(negative regulation of synaptic vesicle exocytosis)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|interpro:IPR038851|reactome:R-DME-170968|reactome:R-DME-354192|reactome:R-DME-381676|reactome:R-DME-392517|reactome:R-DME-5674135|reactome:R-DME-6798695 flybase:FBgn0264324|ensemblmetazoa:FBgn0264324(gene)|ensemblmetazoa:FBtr0330304(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0045874"(positive regulation of sevenless signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR032376|interpro:IPR035892|interpro:IPR036028|interpro:IPR037811|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|reactome:R-DME-9013149|reactome:R-DME-9013404|reactome:R-DME-983231|refseq:NP_733258.4 go:"GO:0005886"(plasma membrane) - - figure legend:5|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-eye_imaginal_disc)|taxid:7227(Drosophila melanogaster) - 2014/09/10 2015/04/29 rogid:mu2X455U2/v4pF+nXz0kpjvYiA07227 rogid:LgFMSKAtFnpo2IL3QNXFDB5z3Pk7227 intact-crc:2C9E03C21A9F1459|rigid:QZ1nPW4RNwGUq7XFI0S3o2ZvRZQ false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody)