#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P36888	uniprotkb:Q12913	intact:EBI-3946257|uniprotkb:B7ZLT7|uniprotkb:F5H0A0|uniprotkb:A0AVG9|uniprotkb:B7ZLT8|uniprotkb:Q13414|ensembl:ENSP00000241453	intact:EBI-2264500|uniprotkb:Q9UDA9|uniprotkb:Q15255|uniprotkb:Q8NHM2|uniprotkb:Q6P4H4|ensembl:ENSP00000400010	psi-mi:flt3_human(display_long)|uniprotkb:FLK2(gene name synonym)|uniprotkb:FL cytokine receptor(gene name synonym)|uniprotkb:Fetal liver kinase-2(gene name synonym)|uniprotkb:FLT3(gene name)|psi-mi:FLT3(display_short)|uniprotkb:STK1(gene name synonym)|uniprotkb:Fms-like tyrosine kinase 3(gene name synonym)|uniprotkb:Stem cell tyrosine kinase 1(gene name synonym)|uniprotkb:CD135(gene name synonym)	psi-mi:ptprj_human(display_long)|uniprotkb:PTPRJ(gene name)|psi-mi:PTPRJ(display_short)|uniprotkb:DEP1(gene name synonym)|uniprotkb:HPTP eta(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase receptor type J(gene name synonym)|uniprotkb:Density-enhanced phosphatase 1(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Böhmer et al. (2013)	imex:IM-23053|pubmed:23650535	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9699658|imex:IM-23053-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0030097"(hemopoiesis)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0097028"(dendritic cell differentiation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001824(Receptor tyrosine kinase, class III, conserved site)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR030118|interpro:IPR036179|mint:P36888|rcsb pdb:1RJB|rcsb pdb:3QS7|rcsb pdb:3QS9|rcsb pdb:4RT7|rcsb pdb:4XUF|rcsb pdb:5X02|rcsb pdb:6IL3|rcsb pdb:6JQR|reactome:R-HSA-109704|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-9607240|go:"GO:0035726"(common myeloid progenitor cell proliferation)|reactome:R-HSA-9645135|reactome:R-HSA-9702509|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043235"(receptor complex)|reactome:R-HSA-9702518|reactome:R-HSA-9702569|reactome:R-HSA-9702577|reactome:R-HSA-9702581|reactome:R-HSA-9702590|reactome:R-HSA-9702596|reactome:R-HSA-9702600|reactome:R-HSA-9702605|go:"GO:0043406"(positive regulation of MAP kinase activity)|reactome:R-HSA-9702614|reactome:R-HSA-9702620|reactome:R-HSA-9702624|reactome:R-HSA-9702632|go:"GO:0043410"(positive regulation of MAPK cascade)|reactome:R-HSA-9702636|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|reactome:R-HSA-9702998|reactome:R-HSA-9703009|reactome:R-HSA-9703648|reactome:R-HSA-9706369|reactome:R-HSA-9706374|go:"GO:0043621"(protein self-association)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046651"(lymphocyte proliferation)|reactome:R-HSA-9706377|ensembl:ENSG00000122025(gene)|ensembl:ENST00000241453(transcript)|go:"GO:0001776"(leukocyte homeostasis)|go:"GO:0002318"(myeloid progenitor cell differentiation)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005021"(vascular endothelial growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010008"(endosome membrane)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019838"(growth factor binding)|refseq:NP_004110.2|dip:DIP-59769N	refseq:NP_002834.3|refseq:NP_001091973.1|go:"GO:0070097"(delta-catenin binding)|go:"GO:1905451"(positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR041201|mint:Q12913|rcsb pdb:2CFV|rcsb pdb:2DLE|rcsb pdb:2NZ6|reactome:R-HSA-202427|reactome:R-HSA-6798695|reactome:R-HSA-6807004|ensembl:ENSG00000149177(gene)|ensembl:ENST00000418331(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005161"(platelet-derived growth factor receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060242"(contact inhibition)|go:"GO:0070062"(extracellular exosome)|go:"GO:0035579"(specific granule membrane)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0006470"(protein dephosphorylation)|reactome:R-HSA-9706369	-	-	-	figure legend:1A|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2014/09/08	2014/10/16	rogid:Y9liE/Q9llf3LbnOegBdnVXZk3c9606	rogid:tGsQm2S/SSUjbnV/WwKSb4rPz/49606	intact-crc:415D4FD5C00221A9|rigid:XCOd7bmwlMddsE4rKYNrwHCo1ik	false	-	mutation increasing interaction strength:1239-1239	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:Q12913	uniprotkb:P36888	intact:EBI-2264500|uniprotkb:Q9UDA9|uniprotkb:Q15255|uniprotkb:Q8NHM2|uniprotkb:Q6P4H4|ensembl:ENSP00000400010	intact:EBI-3946257|uniprotkb:B7ZLT7|uniprotkb:F5H0A0|uniprotkb:A0AVG9|uniprotkb:B7ZLT8|uniprotkb:Q13414|ensembl:ENSP00000241453	psi-mi:ptprj_human(display_long)|uniprotkb:PTPRJ(gene name)|psi-mi:PTPRJ(display_short)|uniprotkb:DEP1(gene name synonym)|uniprotkb:HPTP eta(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase receptor type J(gene name synonym)|uniprotkb:Density-enhanced phosphatase 1(gene name synonym)	psi-mi:flt3_human(display_long)|uniprotkb:FLK2(gene name synonym)|uniprotkb:FL cytokine receptor(gene name synonym)|uniprotkb:Fetal liver kinase-2(gene name synonym)|uniprotkb:FLT3(gene name)|psi-mi:FLT3(display_short)|uniprotkb:STK1(gene name synonym)|uniprotkb:Fms-like tyrosine kinase 3(gene name synonym)|uniprotkb:Stem cell tyrosine kinase 1(gene name synonym)|uniprotkb:CD135(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Böhmer et al. (2013)	imex:IM-23053|pubmed:23650535	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9699672|imex:IM-23053-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002834.3|refseq:NP_001091973.1|go:"GO:0070097"(delta-catenin binding)|go:"GO:1905451"(positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR041201|mint:Q12913|rcsb pdb:2CFV|rcsb pdb:2DLE|rcsb pdb:2NZ6|reactome:R-HSA-202427|reactome:R-HSA-6798695|reactome:R-HSA-6807004|ensembl:ENSG00000149177(gene)|ensembl:ENST00000418331(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005161"(platelet-derived growth factor receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060242"(contact inhibition)|go:"GO:0070062"(extracellular exosome)|go:"GO:0035579"(specific granule membrane)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0006470"(protein dephosphorylation)|reactome:R-HSA-9706369	go:"GO:0030097"(hemopoiesis)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0097028"(dendritic cell differentiation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001824(Receptor tyrosine kinase, class III, conserved site)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR030118|interpro:IPR036179|mint:P36888|rcsb pdb:1RJB|rcsb pdb:3QS7|rcsb pdb:3QS9|rcsb pdb:4RT7|rcsb pdb:4XUF|rcsb pdb:5X02|rcsb pdb:6IL3|rcsb pdb:6JQR|reactome:R-HSA-109704|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-9607240|go:"GO:0035726"(common myeloid progenitor cell proliferation)|reactome:R-HSA-9645135|reactome:R-HSA-9702509|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043235"(receptor complex)|reactome:R-HSA-9702518|reactome:R-HSA-9702569|reactome:R-HSA-9702577|reactome:R-HSA-9702581|reactome:R-HSA-9702590|reactome:R-HSA-9702596|reactome:R-HSA-9702600|reactome:R-HSA-9702605|go:"GO:0043406"(positive regulation of MAP kinase activity)|reactome:R-HSA-9702614|reactome:R-HSA-9702620|reactome:R-HSA-9702624|reactome:R-HSA-9702632|go:"GO:0043410"(positive regulation of MAPK cascade)|reactome:R-HSA-9702636|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|reactome:R-HSA-9702998|reactome:R-HSA-9703009|reactome:R-HSA-9703648|reactome:R-HSA-9706369|reactome:R-HSA-9706374|go:"GO:0043621"(protein self-association)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046651"(lymphocyte proliferation)|reactome:R-HSA-9706377|ensembl:ENSG00000122025(gene)|ensembl:ENST00000241453(transcript)|go:"GO:0001776"(leukocyte homeostasis)|go:"GO:0002318"(myeloid progenitor cell differentiation)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005021"(vascular endothelial growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010008"(endosome membrane)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019838"(growth factor binding)|refseq:NP_004110.2|dip:DIP-59769N	-	-	-	figure legend:1B/C, 2A, 3|agonist:FLT3  ligand|antagonist:Compound 102 -a FLT3 kinase inhibitor  Hydrogen peroxide|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2014/09/08	2014/10/16	rogid:tGsQm2S/SSUjbnV/WwKSb4rPz/49606	rogid:Y9liE/Q9llf3LbnOegBdnVXZk3c9606	intact-crc:7914E951645D6459|rigid:XCOd7bmwlMddsE4rKYNrwHCo1ik	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P36888	uniprotkb:Q12913	intact:EBI-3946257|uniprotkb:B7ZLT7|uniprotkb:F5H0A0|uniprotkb:A0AVG9|uniprotkb:B7ZLT8|uniprotkb:Q13414|ensembl:ENSP00000241453	intact:EBI-2264500|uniprotkb:Q9UDA9|uniprotkb:Q15255|uniprotkb:Q8NHM2|uniprotkb:Q6P4H4|ensembl:ENSP00000400010	psi-mi:flt3_human(display_long)|uniprotkb:FLK2(gene name synonym)|uniprotkb:FL cytokine receptor(gene name synonym)|uniprotkb:Fetal liver kinase-2(gene name synonym)|uniprotkb:FLT3(gene name)|psi-mi:FLT3(display_short)|uniprotkb:STK1(gene name synonym)|uniprotkb:Fms-like tyrosine kinase 3(gene name synonym)|uniprotkb:Stem cell tyrosine kinase 1(gene name synonym)|uniprotkb:CD135(gene name synonym)	psi-mi:ptprj_human(display_long)|uniprotkb:PTPRJ(gene name)|psi-mi:PTPRJ(display_short)|uniprotkb:DEP1(gene name synonym)|uniprotkb:HPTP eta(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase receptor type J(gene name synonym)|uniprotkb:Density-enhanced phosphatase 1(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Böhmer et al. (2013)	imex:IM-23053|pubmed:23650535	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9699689|imex:IM-23053-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0030097"(hemopoiesis)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0097028"(dendritic cell differentiation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001824(Receptor tyrosine kinase, class III, conserved site)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR030118|interpro:IPR036179|mint:P36888|rcsb pdb:1RJB|rcsb pdb:3QS7|rcsb pdb:3QS9|rcsb pdb:4RT7|rcsb pdb:4XUF|rcsb pdb:5X02|rcsb pdb:6IL3|rcsb pdb:6JQR|reactome:R-HSA-109704|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-9607240|go:"GO:0035726"(common myeloid progenitor cell proliferation)|reactome:R-HSA-9645135|reactome:R-HSA-9702509|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043235"(receptor complex)|reactome:R-HSA-9702518|reactome:R-HSA-9702569|reactome:R-HSA-9702577|reactome:R-HSA-9702581|reactome:R-HSA-9702590|reactome:R-HSA-9702596|reactome:R-HSA-9702600|reactome:R-HSA-9702605|go:"GO:0043406"(positive regulation of MAP kinase activity)|reactome:R-HSA-9702614|reactome:R-HSA-9702620|reactome:R-HSA-9702624|reactome:R-HSA-9702632|go:"GO:0043410"(positive regulation of MAPK cascade)|reactome:R-HSA-9702636|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|reactome:R-HSA-9702998|reactome:R-HSA-9703009|reactome:R-HSA-9703648|reactome:R-HSA-9706369|reactome:R-HSA-9706374|go:"GO:0043621"(protein self-association)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046651"(lymphocyte proliferation)|reactome:R-HSA-9706377|ensembl:ENSG00000122025(gene)|ensembl:ENST00000241453(transcript)|go:"GO:0001776"(leukocyte homeostasis)|go:"GO:0002318"(myeloid progenitor cell differentiation)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005021"(vascular endothelial growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010008"(endosome membrane)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019838"(growth factor binding)|refseq:NP_004110.2|dip:DIP-59769N	refseq:NP_002834.3|refseq:NP_001091973.1|go:"GO:0070097"(delta-catenin binding)|go:"GO:1905451"(positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR041201|mint:Q12913|rcsb pdb:2CFV|rcsb pdb:2DLE|rcsb pdb:2NZ6|reactome:R-HSA-202427|reactome:R-HSA-6798695|reactome:R-HSA-6807004|ensembl:ENSG00000149177(gene)|ensembl:ENST00000418331(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005161"(platelet-derived growth factor receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060242"(contact inhibition)|go:"GO:0070062"(extracellular exosome)|go:"GO:0035579"(specific granule membrane)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0006470"(protein dephosphorylation)|reactome:R-HSA-9706369	-	-	-	figure legend:3B|comment:"weak interaction  Internal tandem duplications (ITD) of amino acid stretches can be found in the juxtamembrane domain or in the tyrosine kinase domain;this mutation confers cytokine-independent proliferation and resistance to apoptosis."|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-mv4-11)|taxid:9606(Human MV4-11, Acute Monocytic Leukemia cell line)	-	2014/09/08	2014/10/16	rogid:Y9liE/Q9llf3LbnOegBdnVXZk3c9606	rogid:tGsQm2S/SSUjbnV/WwKSb4rPz/49606	intact-crc:16EB326059EF7BF8|rigid:XCOd7bmwlMddsE4rKYNrwHCo1ik	false	mutation:?-?	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)