#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P70673 uniprotkb:Q63563 intact:EBI-9560239|uniprotkb:Q62906|uniprotkb:Q9JM48|ensembl:ENSRNOP00000028685 intact:EBI-8744493|uniprotkb:O89115 psi-mi:kcj11_rat(display_long)|uniprotkb:Kcnj11(gene name)|psi-mi:Kcnj11(display_short)|uniprotkb:BIR(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir6.2"(gene name synonym)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 11(gene name synonym) psi-mi:abcc9_rat(display_long)|uniprotkb:Abcc9(gene name)|psi-mi:Abcc9(display_short)|uniprotkb:Sulfonylurea receptor 2(gene name synonym)|uniprotkb:Sur2(gene name synonym) psi-mi:"MI:0813"(proximity ligation assay) Lybaert et al. (2013) imex:IM-22655|pubmed:23587463 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:2364"(proximity) psi-mi:"MI:0469"(IntAct) intact:EBI-9560088|imex:IM-22655-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:69247|refseq:NP_112648.2|dip:DIP-58641N|ensembl:ENSRNOG00000021128(gene)|ensembl:ENSRNOT00000028685(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002931"(response to ischemia)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008282"(inward rectifying potassium channel)|go:"GO:0014704"(intercalated disc)|go:"GO:0015272"(ATP-activated inward rectifier potassium channel activity)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0030315"(T-tubule)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030673"(axolemma)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0033198"(response to ATP)|go:"GO:0033574"(response to testosterone)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042493"|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0050877"(nervous system process)|go:"GO:0070852"(cell body fiber)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0098662"(inorganic cation transmembrane transport)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:2001259"(positive regulation of cation channel activity)|interpro:IPR003279(Potassium channel, inwardly rectifying, Kir6.2)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647|rcsb pdb:5TWV|rcsb pdb:6BAA|rcsb pdb:6PZ9|rcsb pdb:6PZA|reactome:R-RNO-1296025|reactome:R-RNO-382556|reactome:R-RNO-422356|reactome:R-RNO-5578775 interpro:IPR000388(Sulphonylurea receptor, N-terminus)|interpro:IPR001475(Sulphonylurea receptor, type 2, N-terminus)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|refseq:NP_037172.2|rgd:3787|interpro:IPR036640|reactome:R-RNO-1296025|reactome:R-RNO-382556|reactome:R-RNO-5578775|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006932"(substrate-dependent cell migration, cell contraction)|go:"GO:0008281"(sulfonylurea receptor activity)|go:"GO:0008282"(inward rectifying potassium channel)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030315"(T-tubule)|go:"GO:0033198"(response to ATP)|go:"GO:0036094"(small molecule binding)|go:"GO:0042493"|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0055085"(transmembrane transport)|go:"GO:0061337"(cardiac conduction)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:0098662"(inorganic cation transmembrane transport)|go:"GO:1990573"(potassium ion import across plasma membrane) - - - figure legend:2C|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-myometrium)|taxid:10116(RAT MYOMETRIUM) - 2014/06/18 2014/10/16 rogid:5ZUdreoVKRhgvPw3N3zwAId+2eg10116 rogid:9+2t8tAz+PwezsKIvDGfwW3VBSQ10116 intact-crc:501A802C12CFC027|rigid:hKg5un0LcJnhb/DW8Tqc4+PZdcE false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:Q14654 uniprotkb:O60706 intact:EBI-2866553|uniprotkb:Q58EX3|uniprotkb:Q2M1H7|uniprotkb:B4DWI4|uniprotkb:E9PNK0|uniprotkb:Q8IW96|ensembl:ENSP00000345708|ensembl:ENSP00000434755 intact:EBI-9008881|ensembl:ENSP00000261201|uniprotkb:O60707 psi-mi:kcj11_human(display_long)|uniprotkb:KCNJ11(gene name)|psi-mi:KCNJ11(display_short)|uniprotkb:IKATP(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir6.2"(gene name synonym)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 11(gene name synonym) psi-mi:abcc9_human(display_long)|uniprotkb:ABCC9(gene name)|psi-mi:ABCC9(display_short)|uniprotkb:SUR2(gene name synonym)|uniprotkb:Sulfonylurea receptor 2(gene name synonym) psi-mi:"MI:0813"(proximity ligation assay) Lybaert et al. (2013) imex:IM-22655|pubmed:23587463 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0469"(IntAct) intact:EBI-9559963|imex:IM-22655-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001159762.1|dip:DIP-58643N|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:2001259"(positive regulation of cation channel activity)|interpro:IPR003279(Potassium channel, inwardly rectifying, Kir6.2)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647|rcsb pdb:6C3O|rcsb pdb:6C3P|reactome:R-HSA-1296025|reactome:R-HSA-382556|reactome:R-HSA-422356|reactome:R-HSA-5578775|reactome:R-HSA-5678420|reactome:R-HSA-5683177|ensembl:ENST00000339994(transcript)|ensembl:ENST00000528731(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002931"(response to ischemia)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008282"(inward rectifying potassium channel)|go:"GO:0014704"(intercalated disc)|go:"GO:0015272"(ATP-activated inward rectifier potassium channel activity)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0030315"(T-tubule)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030673"(axolemma)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0033198"(response to ATP)|go:"GO:0033574"(response to testosterone)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042493"|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0050877"(nervous system process)|go:"GO:0070852"(cell body fiber)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0098662"(inorganic cation transmembrane transport)|ensembl:ENSG00000187486(gene) refseq:XP_011518847.1|go:"GO:0061337"(cardiac conduction)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:0098662"(inorganic cation transmembrane transport)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000388(Sulphonylurea receptor, N-terminus)|interpro:IPR001475(Sulphonylurea receptor, type 2, N-terminus)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|reactome:R-HSA-1296025|reactome:R-HSA-382556|reactome:R-HSA-5578775|reactome:R-HSA-5678420|ensembl:ENSG00000069431(gene)|ensembl:ENST00000261201(transcript)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0008281"(sulfonylurea receptor activity)|go:"GO:0008282"(inward rectifying potassium channel)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0030017"(sarcomere)|go:"GO:0031004"(potassium ion-transporting ATPase complex)|go:"GO:0033198"(response to ATP)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0043225"(ATPase-coupled inorganic anion transmembrane transporter activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0055085"(transmembrane transport)|refseq:NP_005682.2|refseq:NP_064693.2|refseq:XP_005253341.1|refseq:XP_005253343.1|refseq:XP_005253344.1|refseq:XP_005253345.1 - - - figure legend:2A|comment:Coexpression was detected in the syncytiotrophoblast layer.|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-placenta)|taxid:9606(Homo sapiens placenta) - 2014/06/18 2014/10/16 rogid:EgyckzNz0VCMnwzK/U9vz8J2auk9606 rogid:WDuOtY4Ll5cAIxhvQUkvQzlatDs9606 intact-crc:DDFE88371025BC91|rigid:SC7anKlQjx/lbdOFc63fJM1YSjY false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody)