#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q8R313	uniprotkb:Q62739	intact:EBI-9202179	intact:EBI-2028671|uniprotkb:A1L127|ensembl:ENSRNOP00000007258	psi-mi:exoc6_mouse(display_long)|uniprotkb:Exoc6(gene name)|psi-mi:Exoc6(display_short)|uniprotkb:Sec15a(gene name synonym)|uniprotkb:Sec15l1(gene name synonym)|uniprotkb:Exocyst complex component Sec15A(gene name synonym)|uniprotkb:SEC15-like protein 1(gene name synonym)	psi-mi:rab3i_rat(display_long)|uniprotkb:Rab3ip(gene name)|psi-mi:Rab3ip(display_short)|uniprotkb:Rabin3(gene name synonym)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:Rabin8(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chiba et al. (2013)	pubmed:23435566|imex:IM-22606	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9202177|imex:IM-22606-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR007225(Exocyst complex subunit Sec15-like)|interpro:IPR042044|interpro:IPR042045|reactome:R-MMU-264876|reactome:R-MMU-5620916|go:"GO:0000145"(exocyst)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016020"(membrane)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030426"(growth cone)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090522"(vesicle tethering involved in exocytosis)|go:"GO:0090543"(Flemming body)	rgd:620650|refseq:NP_059009.2|refseq:XP_006241419.1|refseq:XP_006241420.1|refseq:XP_006241421.1|refseq:XP_006241422.1|ensembl:ENSRNOG00000005362(gene)|ensembl:ENSRNOT00000007258(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0030027"(lamellipodium)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051020"(GTPase binding)|go:"GO:0051490"(negative regulation of filopodium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:1990635"(proximal dendrite)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|reactome:R-RNO-5620912|reactome:R-RNO-5620916|reactome:R-RNO-5620922|reactome:R-RNO-8876198	-	-	-	figure legend:f6b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line)	-	2014/02/12	2021/02/11	rogid:Y1GSnTfn1f1mFwrz+efnmwIfCSM10090	rogid:xIGhMD0AZHp4HesXNftX6RaVv/o10116	intact-crc:B25A28D6B99F44D8|rigid:FHVbWPIwzQZuxAyIdxIuSW9HrjA	false	flag tag:?-?	yellow fluorescent protein tag:?-?|mutation disrupting interaction:272-272	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q62739	uniprotkb:P62492	intact:EBI-2028671|uniprotkb:A1L127|ensembl:ENSRNOP00000007258	intact:EBI-770256|uniprotkb:P24410|uniprotkb:Q3V1Z6|uniprotkb:Q9JLX1|ensembl:ENSMUSP00000129163	psi-mi:rab3i_rat(display_long)|uniprotkb:Rab3ip(gene name)|psi-mi:Rab3ip(display_short)|uniprotkb:Rabin3(gene name synonym)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:Rabin8(gene name synonym)	psi-mi:rb11a_mouse(display_long)|uniprotkb:Rab11a(gene name)|psi-mi:Rab11a(display_short)|uniprotkb:Rab11(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Chiba et al. (2013)	pubmed:23435566|imex:IM-22606	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-9202154|imex:IM-22606-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:620650|refseq:NP_059009.2|refseq:XP_006241419.1|refseq:XP_006241420.1|refseq:XP_006241421.1|refseq:XP_006241422.1|ensembl:ENSRNOG00000005362(gene)|ensembl:ENSRNOT00000007258(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0030027"(lamellipodium)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051020"(GTPase binding)|go:"GO:0051490"(negative regulation of filopodium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:1990635"(proximal dendrite)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|reactome:R-RNO-5620912|reactome:R-RNO-5620916|reactome:R-RNO-5620922|reactome:R-RNO-8876198	refseq:NP_059078.2|ensembl:ENSMUSG00000004771(gene)|ensembl:ENSMUST00000172298(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0006887"(exocytosis)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008017"(microtubule binding)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010796"(regulation of multivesicular body size)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0030424"(axon)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031489"(myosin V binding)|go:"GO:0031982"(vesicle)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032402"(melanosome transport)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072594"(establishment of protein localization to organelle)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090150"(establishment of protein localization to membrane)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098837"(postsynaptic recycling endosome)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62492|reactome:R-MMU-432040|reactome:R-MMU-5620912|reactome:R-MMU-5620916|reactome:R-MMU-8854214|reactome:R-MMU-8873719|go:"GO:0034394"(protein localization to cell surface)	go:"GO:0005813"(centrosome)	-	-	figure legend:f4b|comment:"When YFP-Rabin8(WT) or the S272A mutant was coexpressed  with CFP-Rab11(QL), Rabin8(S272A) was more  abundantly accumulated on the Rab11(QL)-containing vesicles  around the centrosome than Rabin8(WT) (Figure 4B)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line)	-	2014/02/12	2021/02/11	rogid:xIGhMD0AZHp4HesXNftX6RaVv/o10116	rogid:FjkzGzN2VDTyv94M9vD/EJC2qoU10090	intact-crc:99376D8917EC3A8B|rigid:aJYuXz2O28ajYGxeAz8V4Z5jmZI	false	yellow fluorescent protein tag:?-?|mutation increasing interaction:272-272	cyan fluorescent protein tag:?-?	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P62492	uniprotkb:Q62739	intact:EBI-770256|uniprotkb:P24410|uniprotkb:Q3V1Z6|uniprotkb:Q9JLX1|ensembl:ENSMUSP00000129163	intact:EBI-2028671|uniprotkb:A1L127|ensembl:ENSRNOP00000007258	psi-mi:rb11a_mouse(display_long)|uniprotkb:Rab11a(gene name)|psi-mi:Rab11a(display_short)|uniprotkb:Rab11(gene name synonym)	psi-mi:rab3i_rat(display_long)|uniprotkb:Rab3ip(gene name)|psi-mi:Rab3ip(display_short)|uniprotkb:Rabin3(gene name synonym)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:Rabin8(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Chiba et al. (2013)	pubmed:23435566|imex:IM-22606	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-9202284|imex:IM-22606-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_059078.2|ensembl:ENSMUSG00000004771(gene)|ensembl:ENSMUST00000172298(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0006887"(exocytosis)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008017"(microtubule binding)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010796"(regulation of multivesicular body size)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0030424"(axon)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031489"(myosin V binding)|go:"GO:0031982"(vesicle)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032402"(melanosome transport)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072594"(establishment of protein localization to organelle)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090150"(establishment of protein localization to membrane)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098837"(postsynaptic recycling endosome)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62492|reactome:R-MMU-432040|reactome:R-MMU-5620912|reactome:R-MMU-5620916|reactome:R-MMU-8854214|reactome:R-MMU-8873719|go:"GO:0034394"(protein localization to cell surface)	rgd:620650|refseq:NP_059009.2|refseq:XP_006241419.1|refseq:XP_006241420.1|refseq:XP_006241421.1|refseq:XP_006241422.1|ensembl:ENSRNOG00000005362(gene)|ensembl:ENSRNOT00000007258(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0030027"(lamellipodium)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051020"(GTPase binding)|go:"GO:0051490"(negative regulation of filopodium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:1990635"(proximal dendrite)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|reactome:R-RNO-5620912|reactome:R-RNO-5620916|reactome:R-RNO-5620922|reactome:R-RNO-8876198	go:"GO:0005813"(centrosome)	-	-	figure legend:f6g sf4b|comment:"Rabin8(I329S) was distributed diffusely in the cytoplasm  and did not colocalize with Rab11(QL) on pericentrosomal  vesicles in RPE1 cells (Figure 6G), indicating that binding to  Rab11 and/or PS is required for Rabin8 recruitment and  trafficking to the pericentrosome."|comment:"Rabin8 colocalized  with Rab11(WT) or Rab11(QL) on pericentrosomal  and endosomal vesicles but diffusely distributed in the cytoplasm in cells expressing Rab11(SN) (Supplementary  Figure S4B)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line)	-	2014/02/12	2021/02/11	rogid:FjkzGzN2VDTyv94M9vD/EJC2qoU10090	rogid:xIGhMD0AZHp4HesXNftX6RaVv/o10116	intact-crc:E8AE8A7B1715E4B8|rigid:aJYuXz2O28ajYGxeAz8V4Z5jmZI	false	green fluorescent protein tag:?-?	flag tag:?-?|mutation disrupting interaction:329-329	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0707"(anti tag immunostaining)
uniprotkb:Q8R313	uniprotkb:Q62739	intact:EBI-9202179	intact:EBI-2028671|uniprotkb:A1L127|ensembl:ENSRNOP00000007258	psi-mi:exoc6_mouse(display_long)|uniprotkb:Exoc6(gene name)|psi-mi:Exoc6(display_short)|uniprotkb:Sec15a(gene name synonym)|uniprotkb:Sec15l1(gene name synonym)|uniprotkb:Exocyst complex component Sec15A(gene name synonym)|uniprotkb:SEC15-like protein 1(gene name synonym)	psi-mi:rab3i_rat(display_long)|uniprotkb:Rab3ip(gene name)|psi-mi:Rab3ip(display_short)|uniprotkb:Rabin3(gene name synonym)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:Rabin8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chiba et al. (2013)	pubmed:23435566|imex:IM-22606	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9202210|imex:IM-22606-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR007225(Exocyst complex subunit Sec15-like)|interpro:IPR042044|interpro:IPR042045|reactome:R-MMU-264876|reactome:R-MMU-5620916|go:"GO:0000145"(exocyst)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016020"(membrane)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030426"(growth cone)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090522"(vesicle tethering involved in exocytosis)|go:"GO:0090543"(Flemming body)	rgd:620650|refseq:NP_059009.2|refseq:XP_006241419.1|refseq:XP_006241420.1|refseq:XP_006241421.1|refseq:XP_006241422.1|ensembl:ENSRNOG00000005362(gene)|ensembl:ENSRNOT00000007258(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0030027"(lamellipodium)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051020"(GTPase binding)|go:"GO:0051490"(negative regulation of filopodium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:1990635"(proximal dendrite)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|reactome:R-RNO-5620912|reactome:R-RNO-5620916|reactome:R-RNO-5620922|reactome:R-RNO-8876198	-	-	-	figure legend:f6d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/02/12	2021/02/11	rogid:Y1GSnTfn1f1mFwrz+efnmwIfCSM10090	rogid:xIGhMD0AZHp4HesXNftX6RaVv/o10116	intact-crc:DB0CBECF3E9AB43A|rigid:FHVbWPIwzQZuxAyIdxIuSW9HrjA	false	green fluorescent protein tag:?-?	glutathione s tranferase tag:?-?|mutation increasing interaction:329-329	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q62739	uniprotkb:P62492	intact:EBI-2028671|uniprotkb:A1L127|ensembl:ENSRNOP00000007258	intact:EBI-770256|uniprotkb:P24410|uniprotkb:Q3V1Z6|uniprotkb:Q9JLX1|ensembl:ENSMUSP00000129163	psi-mi:rab3i_rat(display_long)|uniprotkb:Rab3ip(gene name)|psi-mi:Rab3ip(display_short)|uniprotkb:Rabin3(gene name synonym)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:Rabin8(gene name synonym)	psi-mi:rb11a_mouse(display_long)|uniprotkb:Rab11a(gene name)|psi-mi:Rab11a(display_short)|uniprotkb:Rab11(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chiba et al. (2013)	pubmed:23435566|imex:IM-22606	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9202270|imex:IM-22606-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:620650|refseq:NP_059009.2|refseq:XP_006241419.1|refseq:XP_006241420.1|refseq:XP_006241421.1|refseq:XP_006241422.1|ensembl:ENSRNOG00000005362(gene)|ensembl:ENSRNOT00000007258(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0030027"(lamellipodium)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051020"(GTPase binding)|go:"GO:0051490"(negative regulation of filopodium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:1990635"(proximal dendrite)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|reactome:R-RNO-5620912|reactome:R-RNO-5620916|reactome:R-RNO-5620922|reactome:R-RNO-8876198	refseq:NP_059078.2|ensembl:ENSMUSG00000004771(gene)|ensembl:ENSMUST00000172298(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0006887"(exocytosis)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008017"(microtubule binding)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010796"(regulation of multivesicular body size)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0030424"(axon)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031489"(myosin V binding)|go:"GO:0031982"(vesicle)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032402"(melanosome transport)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072594"(establishment of protein localization to organelle)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090150"(establishment of protein localization to membrane)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098837"(postsynaptic recycling endosome)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62492|reactome:R-MMU-432040|reactome:R-MMU-5620912|reactome:R-MMU-5620916|reactome:R-MMU-8854214|reactome:R-MMU-8873719|go:"GO:0034394"(protein localization to cell surface)	-	-	-	figure legend:f6d sf4a sf4c|comment:"Rabin8(I329S) lost the ability to bind to  Rab11(QL) and exhibited increased binding to Sec15  (Figure 6D)."|comment:"Rabin8 bound to Rab11(WT)  and GTP hydrolysis-deficient Rab11(QL), but not to GDPlocked  Rab11(SN) (Supplementary Figure S4A)."|comment:"GST pull-down  assays showed that Rab11(QL) bound to Rabin8(WT) and to  the S272A and S272E mutants to a similar extent  (Supplementary Figure S4C), indicating that Rabin8 phosphorylation  has no apparent effect on its binding to Rab11-  GTP, at least in in vitro binding assays."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/02/12	2021/02/11	rogid:xIGhMD0AZHp4HesXNftX6RaVv/o10116	rogid:FjkzGzN2VDTyv94M9vD/EJC2qoU10090	intact-crc:C76E52B4F4BC2EC6|rigid:aJYuXz2O28ajYGxeAz8V4Z5jmZI	false	mutation disrupting interaction:329-329|glutathione s tranferase tag:?-?	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q62739	uniprotkb:P62492	intact:EBI-2028671|uniprotkb:A1L127|ensembl:ENSRNOP00000007258	intact:EBI-770256|uniprotkb:P24410|uniprotkb:Q3V1Z6|uniprotkb:Q9JLX1|ensembl:ENSMUSP00000129163	psi-mi:rab3i_rat(display_long)|uniprotkb:Rab3ip(gene name)|psi-mi:Rab3ip(display_short)|uniprotkb:Rabin3(gene name synonym)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:Rabin8(gene name synonym)	psi-mi:rb11a_mouse(display_long)|uniprotkb:Rab11a(gene name)|psi-mi:Rab11a(display_short)|uniprotkb:Rab11(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chiba et al. (2013)	pubmed:23435566|imex:IM-22606	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9206835|imex:IM-22606-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:620650|refseq:NP_059009.2|refseq:XP_006241419.1|refseq:XP_006241420.1|refseq:XP_006241421.1|refseq:XP_006241422.1|ensembl:ENSRNOG00000005362(gene)|ensembl:ENSRNOT00000007258(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0030027"(lamellipodium)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051020"(GTPase binding)|go:"GO:0051490"(negative regulation of filopodium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:1990635"(proximal dendrite)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|reactome:R-RNO-5620912|reactome:R-RNO-5620916|reactome:R-RNO-5620922|reactome:R-RNO-8876198	refseq:NP_059078.2|ensembl:ENSMUSG00000004771(gene)|ensembl:ENSMUST00000172298(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0006887"(exocytosis)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008017"(microtubule binding)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010796"(regulation of multivesicular body size)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0030424"(axon)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031489"(myosin V binding)|go:"GO:0031982"(vesicle)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032402"(melanosome transport)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072594"(establishment of protein localization to organelle)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090150"(establishment of protein localization to membrane)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098837"(postsynaptic recycling endosome)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62492|reactome:R-MMU-432040|reactome:R-MMU-5620912|reactome:R-MMU-5620916|reactome:R-MMU-8854214|reactome:R-MMU-8873719|go:"GO:0034394"(protein localization to cell surface)	-	-	-	figure legend:sf4d|comment:"When the post-nuclear supernatants  of cells expressing Rab11(QL) or Rab11(QL, 2CA)  were subjected to coimmunoprecipitation assays with  Rabin8, Rabin8 coprecipitated Rab11(QL) and Rab11(QL,  2CA) to a similar extent (Supplementary Figure S4D), indicating  that the C-terminal lipid modification of Rab11 does  not affect its binding to Rabin8."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/02/12	2021/02/11	rogid:xIGhMD0AZHp4HesXNftX6RaVv/o10116	rogid:FjkzGzN2VDTyv94M9vD/EJC2qoU10090	intact-crc:7D2661269FACDBF2|rigid:aJYuXz2O28ajYGxeAz8V4Z5jmZI	false	flag tag:?-?	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)