#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:E1C4Y2 uniprotkb:R4GRT4 intact:EBI-9077663|ensembl:ENSGALP00000017703 intact:EBI-9077687 psi-mi:e1c4y2_chick(display_long)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short) psi-mi:r4grt4_chick(display_long) psi-mi:"MI:0114"(x-ray crystallography) Nishino et al. (2013) pubmed:23334297|imex:IM-22537 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-9077692|imex:IM-22537-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001264786.1|ensembl:ENSGALG00000010900(gene)|ensembl:ENSGALT00000017724(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|interpro:IPR013255(Kinetochore-Ndc80 subunit Spc25)|rcsb pdb:3VZ9|rcsb pdb:3VZA|reactome:R-GGA-141444|reactome:R-GGA-2467813|reactome:R-GGA-2500257|reactome:R-GGA-5663220|reactome:R-GGA-68877|reactome:R-GGA-9648025 interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|rcsb pdb:3VZA|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division) rcsb pdb:3VZ9 - - figure legend:t1 f3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/01/08 2014/10/16 rogid:7gkfMjZp4vNDoQ9A/RvEzmQD4fA9031 rogid:Zg9Z7PzBnhP2OUjOT/1a8rB9RLk9031 intact-crc:E154D8735CDD525A|rigid:kYvWUqHihYI385gDb8mEAGVnoJw false binding-associated region:131-234 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:F1NPG5 uniprotkb:E1C4Y2 intact:EBI-2132248|ensembl:ENSGALP00000042737 intact:EBI-9077663|ensembl:ENSGALP00000017703 psi-mi:cenpt_chick(display_long)|uniprotkb:CENPT(gene name)|psi-mi:CENPT(display_short) psi-mi:e1c4y2_chick(display_long)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short) psi-mi:"MI:0114"(x-ray crystallography) Nishino et al. (2013) pubmed:23334297|imex:IM-22537 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9077677|imex:IM-22537-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001263242.1|ensembl:ENSGALG00000028900(gene)|ensembl:ENSGALT00000043964(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:1903394"(protein localization to kinetochore involved in kinetochore assembly)|interpro:IPR009072(Histone-fold)|interpro:IPR028255|interpro:IPR032373|interpro:IPR035425|rcsb pdb:3B0C|rcsb pdb:3B0D|rcsb pdb:3VH5|rcsb pdb:3VH6|rcsb pdb:3VZA refseq:NP_001264786.1|ensembl:ENSGALG00000010900(gene)|ensembl:ENSGALT00000017724(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|interpro:IPR013255(Kinetochore-Ndc80 subunit Spc25)|rcsb pdb:3VZ9|rcsb pdb:3VZA|reactome:R-GGA-141444|reactome:R-GGA-2467813|reactome:R-GGA-2500257|reactome:R-GGA-5663220|reactome:R-GGA-68877|reactome:R-GGA-9648025 rcsb pdb:3VZA - - figure legend:t1 f3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/01/08 2014/10/16 rogid:kRNRHK5vtM8zuKPUe8EHn/G7U6E9031 rogid:7gkfMjZp4vNDoQ9A/RvEzmQD4fA9031 intact-crc:6C0C9B8A63ACA2ED|rigid:hscvY2vF89TSLyvzzcBC4YU7L3w false binding-associated region:63-98 binding-associated region:131-234 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:F1NPG5 uniprotkb:R4GRT4 intact:EBI-2132248|ensembl:ENSGALP00000042737 intact:EBI-9077687 psi-mi:cenpt_chick(display_long)|uniprotkb:CENPT(gene name)|psi-mi:CENPT(display_short) psi-mi:r4grt4_chick(display_long) psi-mi:"MI:0114"(x-ray crystallography) Nishino et al. (2013) pubmed:23334297|imex:IM-22537 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9077677|imex:IM-22537-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001263242.1|ensembl:ENSGALG00000028900(gene)|ensembl:ENSGALT00000043964(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:1903394"(protein localization to kinetochore involved in kinetochore assembly)|interpro:IPR009072(Histone-fold)|interpro:IPR028255|interpro:IPR032373|interpro:IPR035425|rcsb pdb:3B0C|rcsb pdb:3B0D|rcsb pdb:3VH5|rcsb pdb:3VH6|rcsb pdb:3VZA interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|rcsb pdb:3VZA|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division) rcsb pdb:3VZA - - figure legend:t1 f3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/01/08 2014/10/16 rogid:kRNRHK5vtM8zuKPUe8EHn/G7U6E9031 rogid:Zg9Z7PzBnhP2OUjOT/1a8rB9RLk9031 intact-crc:6C0C9B8A63ACA2ED|rigid:hscvY2vF89TSLyvzzcBC4YU7L3w false binding-associated region:63-98 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:F1NPG5 uniprotkb:E1C4Y2 intact:EBI-2132248|ensembl:ENSGALP00000042737 intact:EBI-9077663|ensembl:ENSGALP00000017703 psi-mi:cenpt_chick(display_long)|uniprotkb:CENPT(gene name)|psi-mi:CENPT(display_short) psi-mi:e1c4y2_chick(display_long)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short) psi-mi:"MI:0065"(isothermal titration calorimetry) Nishino et al. (2013) pubmed:23334297|imex:IM-22537 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9077741|imex:IM-22537-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001263242.1|ensembl:ENSGALG00000028900(gene)|ensembl:ENSGALT00000043964(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:1903394"(protein localization to kinetochore involved in kinetochore assembly)|interpro:IPR009072(Histone-fold)|interpro:IPR028255|interpro:IPR032373|interpro:IPR035425|rcsb pdb:3B0C|rcsb pdb:3B0D|rcsb pdb:3VH5|rcsb pdb:3VH6|rcsb pdb:3VZA refseq:NP_001264786.1|ensembl:ENSGALG00000010900(gene)|ensembl:ENSGALT00000017724(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|interpro:IPR013255(Kinetochore-Ndc80 subunit Spc25)|rcsb pdb:3VZ9|rcsb pdb:3VZA|reactome:R-GGA-141444|reactome:R-GGA-2467813|reactome:R-GGA-2500257|reactome:R-GGA-5663220|reactome:R-GGA-68877|reactome:R-GGA-9648025 - - - figure legend:f2d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:481.0x10^-9 2014/01/08 2014/10/16 rogid:kRNRHK5vtM8zuKPUe8EHn/G7U6E9031 rogid:7gkfMjZp4vNDoQ9A/RvEzmQD4fA9031 intact-crc:5C14C84DB80C17F1|rigid:hscvY2vF89TSLyvzzcBC4YU7L3w false binding-associated region:63-98|mutation increasing interaction:88-88,72-72 binding-associated region:131-234 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:F1NPG5 uniprotkb:R4GRT4 intact:EBI-2132248|ensembl:ENSGALP00000042737 intact:EBI-9077687 psi-mi:cenpt_chick(display_long)|uniprotkb:CENPT(gene name)|psi-mi:CENPT(display_short) psi-mi:r4grt4_chick(display_long) psi-mi:"MI:0065"(isothermal titration calorimetry) Nishino et al. (2013) pubmed:23334297|imex:IM-22537 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9077741|imex:IM-22537-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001263242.1|ensembl:ENSGALG00000028900(gene)|ensembl:ENSGALT00000043964(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:1903394"(protein localization to kinetochore involved in kinetochore assembly)|interpro:IPR009072(Histone-fold)|interpro:IPR028255|interpro:IPR032373|interpro:IPR035425|rcsb pdb:3B0C|rcsb pdb:3B0D|rcsb pdb:3VH5|rcsb pdb:3VH6|rcsb pdb:3VZA interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|rcsb pdb:3VZA|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division) - - - figure legend:f2d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:481.0x10^-9 2014/01/08 2014/10/16 rogid:kRNRHK5vtM8zuKPUe8EHn/G7U6E9031 rogid:Zg9Z7PzBnhP2OUjOT/1a8rB9RLk9031 intact-crc:5C14C84DB80C17F1|rigid:hscvY2vF89TSLyvzzcBC4YU7L3w false binding-associated region:63-98|mutation increasing interaction:88-88,72-72 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:F1NPG5 uniprotkb:E1C4Y2 intact:EBI-2132248|ensembl:ENSGALP00000042737 intact:EBI-9077663|ensembl:ENSGALP00000017703 psi-mi:cenpt_chick(display_long)|uniprotkb:CENPT(gene name)|psi-mi:CENPT(display_short) psi-mi:e1c4y2_chick(display_long)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short) psi-mi:"MI:0065"(isothermal titration calorimetry) Nishino et al. (2013) pubmed:23334297|imex:IM-22537 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9077770|imex:IM-22537-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001263242.1|ensembl:ENSGALG00000028900(gene)|ensembl:ENSGALT00000043964(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:1903394"(protein localization to kinetochore involved in kinetochore assembly)|interpro:IPR009072(Histone-fold)|interpro:IPR028255|interpro:IPR032373|interpro:IPR035425|rcsb pdb:3B0C|rcsb pdb:3B0D|rcsb pdb:3VH5|rcsb pdb:3VH6|rcsb pdb:3VZA refseq:NP_001264786.1|ensembl:ENSGALG00000010900(gene)|ensembl:ENSGALT00000017724(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|interpro:IPR013255(Kinetochore-Ndc80 subunit Spc25)|rcsb pdb:3VZ9|rcsb pdb:3VZA|reactome:R-GGA-141444|reactome:R-GGA-2467813|reactome:R-GGA-2500257|reactome:R-GGA-5663220|reactome:R-GGA-68877|reactome:R-GGA-9648025 - - - figure legend:f2h|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:1.29x10^-6 2014/01/08 2014/10/16 rogid:kRNRHK5vtM8zuKPUe8EHn/G7U6E9031 rogid:7gkfMjZp4vNDoQ9A/RvEzmQD4fA9031 intact-crc:E5708635073BB20C|rigid:hscvY2vF89TSLyvzzcBC4YU7L3w false phosphorylated residue:72-72|binding-associated region:63-98 binding-associated region:131-234 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:F1NPG5 uniprotkb:R4GRT4 intact:EBI-2132248|ensembl:ENSGALP00000042737 intact:EBI-9077687 psi-mi:cenpt_chick(display_long)|uniprotkb:CENPT(gene name)|psi-mi:CENPT(display_short) psi-mi:r4grt4_chick(display_long) psi-mi:"MI:0065"(isothermal titration calorimetry) Nishino et al. (2013) pubmed:23334297|imex:IM-22537 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9077770|imex:IM-22537-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001263242.1|ensembl:ENSGALG00000028900(gene)|ensembl:ENSGALT00000043964(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:1903394"(protein localization to kinetochore involved in kinetochore assembly)|interpro:IPR009072(Histone-fold)|interpro:IPR028255|interpro:IPR032373|interpro:IPR035425|rcsb pdb:3B0C|rcsb pdb:3B0D|rcsb pdb:3VH5|rcsb pdb:3VH6|rcsb pdb:3VZA interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|rcsb pdb:3VZA|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division) - - - figure legend:f2h|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:1.29x10^-6 2014/01/08 2014/10/16 rogid:kRNRHK5vtM8zuKPUe8EHn/G7U6E9031 rogid:Zg9Z7PzBnhP2OUjOT/1a8rB9RLk9031 intact-crc:E5708635073BB20C|rigid:hscvY2vF89TSLyvzzcBC4YU7L3w false phosphorylated residue:72-72|binding-associated region:63-98 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:F1NPG5 uniprotkb:E1C4Y2 intact:EBI-2132248|ensembl:ENSGALP00000042737 intact:EBI-9077663|ensembl:ENSGALP00000017703 psi-mi:cenpt_chick(display_long)|uniprotkb:CENPT(gene name)|psi-mi:CENPT(display_short) psi-mi:e1c4y2_chick(display_long)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short) psi-mi:"MI:0065"(isothermal titration calorimetry) Nishino et al. (2013) pubmed:23334297|imex:IM-22537 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9077783|imex:IM-22537-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001263242.1|ensembl:ENSGALG00000028900(gene)|ensembl:ENSGALT00000043964(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:1903394"(protein localization to kinetochore involved in kinetochore assembly)|interpro:IPR009072(Histone-fold)|interpro:IPR028255|interpro:IPR032373|interpro:IPR035425|rcsb pdb:3B0C|rcsb pdb:3B0D|rcsb pdb:3VH5|rcsb pdb:3VH6|rcsb pdb:3VZA refseq:NP_001264786.1|ensembl:ENSGALG00000010900(gene)|ensembl:ENSGALT00000017724(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|interpro:IPR013255(Kinetochore-Ndc80 subunit Spc25)|rcsb pdb:3VZ9|rcsb pdb:3VZA|reactome:R-GGA-141444|reactome:R-GGA-2467813|reactome:R-GGA-2500257|reactome:R-GGA-5663220|reactome:R-GGA-68877|reactome:R-GGA-9648025 - - - figure legend:f2g|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:518.0x10^-9 2014/01/08 2014/10/16 rogid:kRNRHK5vtM8zuKPUe8EHn/G7U6E9031 rogid:7gkfMjZp4vNDoQ9A/RvEzmQD4fA9031 intact-crc:79F47D3E3BC1D708|rigid:hscvY2vF89TSLyvzzcBC4YU7L3w false phosphorylated residue:88-88|binding-associated region:63-98|phosphorylated residue:72-72 binding-associated region:131-234 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:F1NPG5 uniprotkb:R4GRT4 intact:EBI-2132248|ensembl:ENSGALP00000042737 intact:EBI-9077687 psi-mi:cenpt_chick(display_long)|uniprotkb:CENPT(gene name)|psi-mi:CENPT(display_short) psi-mi:r4grt4_chick(display_long) psi-mi:"MI:0065"(isothermal titration calorimetry) Nishino et al. (2013) pubmed:23334297|imex:IM-22537 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9077783|imex:IM-22537-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001263242.1|ensembl:ENSGALG00000028900(gene)|ensembl:ENSGALT00000043964(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:1903394"(protein localization to kinetochore involved in kinetochore assembly)|interpro:IPR009072(Histone-fold)|interpro:IPR028255|interpro:IPR032373|interpro:IPR035425|rcsb pdb:3B0C|rcsb pdb:3B0D|rcsb pdb:3VH5|rcsb pdb:3VH6|rcsb pdb:3VZA interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|rcsb pdb:3VZA|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division) - - - figure legend:f2g|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:518.0x10^-9 2014/01/08 2014/10/16 rogid:kRNRHK5vtM8zuKPUe8EHn/G7U6E9031 rogid:Zg9Z7PzBnhP2OUjOT/1a8rB9RLk9031 intact-crc:79F47D3E3BC1D708|rigid:hscvY2vF89TSLyvzzcBC4YU7L3w false phosphorylated residue:88-88|binding-associated region:63-98|phosphorylated residue:72-72 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:F1NPG5 uniprotkb:E1C4Y2 intact:EBI-2132248|ensembl:ENSGALP00000042737 intact:EBI-9077663|ensembl:ENSGALP00000017703 psi-mi:cenpt_chick(display_long)|uniprotkb:CENPT(gene name)|psi-mi:CENPT(display_short) psi-mi:e1c4y2_chick(display_long)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short) psi-mi:"MI:0065"(isothermal titration calorimetry) Nishino et al. (2013) pubmed:23334297|imex:IM-22537 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9077729|imex:IM-22537-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001263242.1|ensembl:ENSGALG00000028900(gene)|ensembl:ENSGALT00000043964(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:1903394"(protein localization to kinetochore involved in kinetochore assembly)|interpro:IPR009072(Histone-fold)|interpro:IPR028255|interpro:IPR032373|interpro:IPR035425|rcsb pdb:3B0C|rcsb pdb:3B0D|rcsb pdb:3VH5|rcsb pdb:3VH6|rcsb pdb:3VZA refseq:NP_001264786.1|ensembl:ENSGALG00000010900(gene)|ensembl:ENSGALT00000017724(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|interpro:IPR013255(Kinetochore-Ndc80 subunit Spc25)|rcsb pdb:3VZ9|rcsb pdb:3VZA|reactome:R-GGA-141444|reactome:R-GGA-2467813|reactome:R-GGA-2500257|reactome:R-GGA-5663220|reactome:R-GGA-68877|reactome:R-GGA-9648025 - - - figure legend:f2f|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:6.67x10^-6 2014/01/08 2014/10/16 rogid:kRNRHK5vtM8zuKPUe8EHn/G7U6E9031 rogid:7gkfMjZp4vNDoQ9A/RvEzmQD4fA9031 intact-crc:E846E4FDA8ACB256|rigid:hscvY2vF89TSLyvzzcBC4YU7L3w false binding-associated region:63-98 binding-associated region:131-234 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:F1NPG5 uniprotkb:R4GRT4 intact:EBI-2132248|ensembl:ENSGALP00000042737 intact:EBI-9077687 psi-mi:cenpt_chick(display_long)|uniprotkb:CENPT(gene name)|psi-mi:CENPT(display_short) psi-mi:r4grt4_chick(display_long) psi-mi:"MI:0065"(isothermal titration calorimetry) Nishino et al. (2013) pubmed:23334297|imex:IM-22537 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9077729|imex:IM-22537-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001263242.1|ensembl:ENSGALG00000028900(gene)|ensembl:ENSGALT00000043964(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:1903394"(protein localization to kinetochore involved in kinetochore assembly)|interpro:IPR009072(Histone-fold)|interpro:IPR028255|interpro:IPR032373|interpro:IPR035425|rcsb pdb:3B0C|rcsb pdb:3B0D|rcsb pdb:3VH5|rcsb pdb:3VH6|rcsb pdb:3VZA interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|rcsb pdb:3VZA|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division) - - - figure legend:f2f|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:6.67x10^-6 2014/01/08 2014/10/16 rogid:kRNRHK5vtM8zuKPUe8EHn/G7U6E9031 rogid:Zg9Z7PzBnhP2OUjOT/1a8rB9RLk9031 intact-crc:E846E4FDA8ACB256|rigid:hscvY2vF89TSLyvzzcBC4YU7L3w false binding-associated region:63-98 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:F1NPG5 uniprotkb:E1C4Y2 intact:EBI-2132248|ensembl:ENSGALP00000042737 intact:EBI-9077663|ensembl:ENSGALP00000017703 psi-mi:cenpt_chick(display_long)|uniprotkb:CENPT(gene name)|psi-mi:CENPT(display_short) psi-mi:e1c4y2_chick(display_long)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short) psi-mi:"MI:0065"(isothermal titration calorimetry) Nishino et al. (2013) pubmed:23334297|imex:IM-22537 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9077755|imex:IM-22537-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001263242.1|ensembl:ENSGALG00000028900(gene)|ensembl:ENSGALT00000043964(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:1903394"(protein localization to kinetochore involved in kinetochore assembly)|interpro:IPR009072(Histone-fold)|interpro:IPR028255|interpro:IPR032373|interpro:IPR035425|rcsb pdb:3B0C|rcsb pdb:3B0D|rcsb pdb:3VH5|rcsb pdb:3VH6|rcsb pdb:3VZA refseq:NP_001264786.1|ensembl:ENSGALG00000010900(gene)|ensembl:ENSGALT00000017724(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|interpro:IPR013255(Kinetochore-Ndc80 subunit Spc25)|rcsb pdb:3VZ9|rcsb pdb:3VZA|reactome:R-GGA-141444|reactome:R-GGA-2467813|reactome:R-GGA-2500257|reactome:R-GGA-5663220|reactome:R-GGA-68877|reactome:R-GGA-9648025 - - - figure legend:f2e|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:610.0x10^-9 2014/01/08 2014/10/16 rogid:kRNRHK5vtM8zuKPUe8EHn/G7U6E9031 rogid:7gkfMjZp4vNDoQ9A/RvEzmQD4fA9031 intact-crc:00F642AB3907943F|rigid:hscvY2vF89TSLyvzzcBC4YU7L3w false binding-associated region:63-98|mutation increasing interaction:72-72 binding-associated region:131-234 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:F1NPG5 uniprotkb:R4GRT4 intact:EBI-2132248|ensembl:ENSGALP00000042737 intact:EBI-9077687 psi-mi:cenpt_chick(display_long)|uniprotkb:CENPT(gene name)|psi-mi:CENPT(display_short) psi-mi:r4grt4_chick(display_long) psi-mi:"MI:0065"(isothermal titration calorimetry) Nishino et al. (2013) pubmed:23334297|imex:IM-22537 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9077755|imex:IM-22537-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001263242.1|ensembl:ENSGALG00000028900(gene)|ensembl:ENSGALT00000043964(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:1903394"(protein localization to kinetochore involved in kinetochore assembly)|interpro:IPR009072(Histone-fold)|interpro:IPR028255|interpro:IPR032373|interpro:IPR035425|rcsb pdb:3B0C|rcsb pdb:3B0D|rcsb pdb:3VH5|rcsb pdb:3VH6|rcsb pdb:3VZA interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|rcsb pdb:3VZA|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division) - - - figure legend:f2e|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:610.0x10^-9 2014/01/08 2014/10/16 rogid:kRNRHK5vtM8zuKPUe8EHn/G7U6E9031 rogid:Zg9Z7PzBnhP2OUjOT/1a8rB9RLk9031 intact-crc:00F642AB3907943F|rigid:hscvY2vF89TSLyvzzcBC4YU7L3w false binding-associated region:63-98|mutation increasing interaction:72-72 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NG31 uniprotkb:Q9H081 intact:EBI-1001161|intact:EBI-2555927|uniprotkb:Q8NHE1|uniprotkb:Q8WXA6|uniprotkb:Q9HCK2|uniprotkb:Q9NR92|ensembl:ENSP00000335463 intact:EBI-1001205|uniprotkb:Q96N24|ensembl:ENSP00000370557|ensembl:ENSP00000461252|ensembl:ENSP00000484532 psi-mi:knl1_human(display_long)|uniprotkb:KNL1(gene name)|psi-mi:KNL1(display_short)|uniprotkb:ALL1-fused gene from chromosome 15q14 protein(gene name synonym)|uniprotkb:Bub-linking kinetochore protein(gene name synonym)|uniprotkb:CASC5(gene name synonym)|uniprotkb:Cancer susceptibility candidate gene 5 protein(gene name synonym)|uniprotkb:Cancer/testis antigen 29(gene name synonym)|uniprotkb:KIAA1570(gene name synonym)|uniprotkb:Kinetochore-null protein 1(gene name synonym)|uniprotkb:Protein CASC5(gene name synonym)|uniprotkb:Protein D40/AF15q14(gene name synonym) psi-mi:mis12_human(display_long)|uniprotkb:MIS12(gene name)|psi-mi:MIS12(display_short) psi-mi:"MI:0065"(isothermal titration calorimetry) Nishino et al. (2013) pubmed:23334297|imex:IM-22537 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9077890|imex:IM-22537-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000137812(gene)|ensembl:ENST00000346991(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001675"(acrosome assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016604"(nuclear body)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|interpro:IPR037388|interpro:IPR040850|interpro:IPR043651|mint:Q8NG31|rcsb pdb:3SI5|rcsb pdb:4A1G|rcsb pdb:4NF9|rcsb pdb:4NFA|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_653091.3|refseq:NP_733468.3|ensembl:ENSP00000335463|ensembl:ENST00000399668|ensembl:ENSP00000382576|dip:DIP-36474N refseq:NP_001245146.1|refseq:NP_001245147.1|refseq:NP_001245148.1|refseq:NP_001245149.1|refseq:XP_016880522.1|refseq:XP_016880523.1|refseq:XP_016880524.1|refseq:NP_076944.1|ensembl:ENSG00000167842(gene)|ensembl:ENST00000381165(transcript)|ensembl:ENST00000573759(transcript)|ensembl:ENST00000611091(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR008685(Mis12)|mint:Q9H081|rcsb pdb:5LSJ|rcsb pdb:5LSK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-5663220|refseq:XP_005256854.1 - - - figure legend:sf5d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:291.0x10^-9 2014/01/08 2014/10/16 rogid:VrKgxXm7DGkpFhJjZ98oQhkr5Eo9606 rogid:1qNMwDq3AYOWnRnPa2u3yt7O4109606 intact-crc:6DD1A2AFAC20E4EE|rigid:tJQTkZBGCeSsLFtGzu7vg3LBwtY false binding-associated region:2106-2316 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NG31 uniprotkb:Q8NBT2 intact:EBI-1001161|intact:EBI-2555927|uniprotkb:Q8NHE1|uniprotkb:Q8WXA6|uniprotkb:Q9HCK2|uniprotkb:Q9NR92|ensembl:ENSP00000335463 intact:EBI-999900|uniprotkb:C9JGC4|ensembl:ENSP00000465075|uniprotkb:B4DZZ7 psi-mi:knl1_human(display_long)|uniprotkb:KNL1(gene name)|psi-mi:KNL1(display_short)|uniprotkb:ALL1-fused gene from chromosome 15q14 protein(gene name synonym)|uniprotkb:Bub-linking kinetochore protein(gene name synonym)|uniprotkb:CASC5(gene name synonym)|uniprotkb:Cancer susceptibility candidate gene 5 protein(gene name synonym)|uniprotkb:Cancer/testis antigen 29(gene name synonym)|uniprotkb:KIAA1570(gene name synonym)|uniprotkb:Kinetochore-null protein 1(gene name synonym)|uniprotkb:Protein CASC5(gene name synonym)|uniprotkb:Protein D40/AF15q14(gene name synonym) psi-mi:spc24_human(display_long)|uniprotkb:SPBC24(gene name synonym)|uniprotkb:SPC24(gene name)|psi-mi:SPC24(display_short) psi-mi:"MI:0065"(isothermal titration calorimetry) Nishino et al. (2013) pubmed:23334297|imex:IM-22537 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9077890|imex:IM-22537-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000137812(gene)|ensembl:ENST00000346991(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001675"(acrosome assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016604"(nuclear body)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|interpro:IPR037388|interpro:IPR040850|interpro:IPR043651|mint:Q8NG31|rcsb pdb:3SI5|rcsb pdb:4A1G|rcsb pdb:4NF9|rcsb pdb:4NFA|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_653091.3|refseq:NP_733468.3|ensembl:ENSP00000335463|ensembl:ENST00000399668|ensembl:ENSP00000382576|dip:DIP-36474N refseq:NP_872319.1|ensembl:ENSG00000161888(gene)|ensembl:ENST00000592540(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|mint:Q8NBT2|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_001303960.1|refseq:NP_001303962.1|refseq:XP_005259810.1|dip:DIP-35754N - - - figure legend:sf5d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:291.0x10^-9 2014/01/08 2014/10/16 rogid:VrKgxXm7DGkpFhJjZ98oQhkr5Eo9606 rogid:ANMEuzMkpwcbiSjx6OaHAK8vVcA9606 intact-crc:6DD1A2AFAC20E4EE|rigid:tJQTkZBGCeSsLFtGzu7vg3LBwtY false binding-associated region:2106-2316 binding-associated region:57-197 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NG31 uniprotkb:Q9HBM1 intact:EBI-1001161|intact:EBI-2555927|uniprotkb:Q8NHE1|uniprotkb:Q8WXA6|uniprotkb:Q9HCK2|uniprotkb:Q9NR92|ensembl:ENSP00000335463 intact:EBI-999909|ensembl:ENSP00000282074|ensembl:ENSP00000481354|ensembl:ENSP00000483050|uniprotkb:D3DPC0|uniprotkb:A8K4X8 psi-mi:knl1_human(display_long)|uniprotkb:KNL1(gene name)|psi-mi:KNL1(display_short)|uniprotkb:ALL1-fused gene from chromosome 15q14 protein(gene name synonym)|uniprotkb:Bub-linking kinetochore protein(gene name synonym)|uniprotkb:CASC5(gene name synonym)|uniprotkb:Cancer susceptibility candidate gene 5 protein(gene name synonym)|uniprotkb:Cancer/testis antigen 29(gene name synonym)|uniprotkb:KIAA1570(gene name synonym)|uniprotkb:Kinetochore-null protein 1(gene name synonym)|uniprotkb:Protein CASC5(gene name synonym)|uniprotkb:Protein D40/AF15q14(gene name synonym) psi-mi:spc25_human(display_long)|uniprotkb:AD024(orf name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short)|uniprotkb:SPBC25(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Nishino et al. (2013) pubmed:23334297|imex:IM-22537 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9077890|imex:IM-22537-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000137812(gene)|ensembl:ENST00000346991(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001675"(acrosome assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016604"(nuclear body)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|interpro:IPR037388|interpro:IPR040850|interpro:IPR043651|mint:Q8NG31|rcsb pdb:3SI5|rcsb pdb:4A1G|rcsb pdb:4NF9|rcsb pdb:4NFA|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_653091.3|refseq:NP_733468.3|ensembl:ENSP00000335463|ensembl:ENST00000399668|ensembl:ENSP00000382576|dip:DIP-36474N refseq:NP_065726.1|ensembl:ENSG00000277909(gene)|ensembl:ENST00000282074(transcript)|ensembl:ENST00000611144(transcript)|ensembl:ENST00000616584(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|interpro:IPR013255(Kinetochore-Ndc80 subunit Spc25)|mint:Q9HBM1|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENSG00000152253(gene)|dip:DIP-35753N - - - figure legend:sf5d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:291.0x10^-9 2014/01/08 2014/10/16 rogid:VrKgxXm7DGkpFhJjZ98oQhkr5Eo9606 rogid:qR1LJPKAJwXtOdzKs4Zg0PqJrBM9606 intact-crc:6DD1A2AFAC20E4EE|rigid:tJQTkZBGCeSsLFtGzu7vg3LBwtY false binding-associated region:2106-2316 binding-associated region:70-224|mutation decreasing interaction:149-149,154-154 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96BT3 uniprotkb:Q8NBT2 intact:EBI-719918|uniprotkb:Q96I29|uniprotkb:Q96IC6|uniprotkb:Q96NK9|uniprotkb:Q9H901|ensembl:ENSP00000400140|ensembl:ENSP00000457810 intact:EBI-999900|uniprotkb:C9JGC4|ensembl:ENSP00000465075|uniprotkb:B4DZZ7 psi-mi:cenpt_human(display_long)|uniprotkb:Interphase centromere complex protein 22(gene name synonym)|uniprotkb:CENPT(gene name)|psi-mi:CENPT(display_short)|uniprotkb:C16orf56(gene name synonym)|uniprotkb:ICEN22(gene name synonym) psi-mi:spc24_human(display_long)|uniprotkb:SPBC24(gene name synonym)|uniprotkb:SPC24(gene name)|psi-mi:SPC24(display_short) psi-mi:"MI:0065"(isothermal titration calorimetry) Nishino et al. (2013) pubmed:23334297|imex:IM-22537 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9077859|imex:IM-22537-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079358.3|ensembl:ENSG00000102901(gene)|ensembl:ENST00000440851(transcript)|ensembl:ENST00000562787(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051276"(chromosome organization)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|go:"GO:1903394"(protein localization to kinetochore involved in kinetochore assembly)|interpro:IPR009072(Histone-fold)|interpro:IPR028255|interpro:IPR032373|interpro:IPR035425|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025 refseq:NP_872319.1|ensembl:ENSG00000161888(gene)|ensembl:ENST00000592540(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|mint:Q8NBT2|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_001303960.1|refseq:NP_001303962.1|refseq:XP_005259810.1|dip:DIP-35754N - - - figure legend:sf5b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:58.1x10^-9 2014/01/08 2014/10/16 rogid:TVIRAvfopdj+sRVaAOHj5xxYssg9606 rogid:ANMEuzMkpwcbiSjx6OaHAK8vVcA9606 intact-crc:2E3B6EB9D4122A25|rigid:3h5fhLmMA85P6gyUhlpFebMlQwY false mutation increasing interaction:85-85|binding-associated region:76-106|maltose binding protein tag:?-? binding-associated region:57-197 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96BT3 uniprotkb:Q9HBM1 intact:EBI-719918|uniprotkb:Q96I29|uniprotkb:Q96IC6|uniprotkb:Q96NK9|uniprotkb:Q9H901|ensembl:ENSP00000400140|ensembl:ENSP00000457810 intact:EBI-999909|ensembl:ENSP00000282074|ensembl:ENSP00000481354|ensembl:ENSP00000483050|uniprotkb:D3DPC0|uniprotkb:A8K4X8 psi-mi:cenpt_human(display_long)|uniprotkb:Interphase centromere complex protein 22(gene name synonym)|uniprotkb:CENPT(gene name)|psi-mi:CENPT(display_short)|uniprotkb:C16orf56(gene name synonym)|uniprotkb:ICEN22(gene name synonym) psi-mi:spc25_human(display_long)|uniprotkb:AD024(orf name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short)|uniprotkb:SPBC25(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Nishino et al. (2013) pubmed:23334297|imex:IM-22537 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9077859|imex:IM-22537-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079358.3|ensembl:ENSG00000102901(gene)|ensembl:ENST00000440851(transcript)|ensembl:ENST00000562787(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051276"(chromosome organization)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|go:"GO:1903394"(protein localization to kinetochore involved in kinetochore assembly)|interpro:IPR009072(Histone-fold)|interpro:IPR028255|interpro:IPR032373|interpro:IPR035425|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025 refseq:NP_065726.1|ensembl:ENSG00000277909(gene)|ensembl:ENST00000282074(transcript)|ensembl:ENST00000611144(transcript)|ensembl:ENST00000616584(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|interpro:IPR013255(Kinetochore-Ndc80 subunit Spc25)|mint:Q9HBM1|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENSG00000152253(gene)|dip:DIP-35753N - - - figure legend:sf5b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:58.1x10^-9 2014/01/08 2014/10/16 rogid:TVIRAvfopdj+sRVaAOHj5xxYssg9606 rogid:qR1LJPKAJwXtOdzKs4Zg0PqJrBM9606 intact-crc:2E3B6EB9D4122A25|rigid:3h5fhLmMA85P6gyUhlpFebMlQwY false mutation increasing interaction:85-85|binding-associated region:76-106|maltose binding protein tag:?-? binding-associated region:70-224 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96BT3 uniprotkb:Q8NBT2 intact:EBI-719918|uniprotkb:Q96I29|uniprotkb:Q96IC6|uniprotkb:Q96NK9|uniprotkb:Q9H901|ensembl:ENSP00000400140|ensembl:ENSP00000457810 intact:EBI-999900|uniprotkb:C9JGC4|ensembl:ENSP00000465075|uniprotkb:B4DZZ7 psi-mi:cenpt_human(display_long)|uniprotkb:Interphase centromere complex protein 22(gene name synonym)|uniprotkb:CENPT(gene name)|psi-mi:CENPT(display_short)|uniprotkb:C16orf56(gene name synonym)|uniprotkb:ICEN22(gene name synonym) psi-mi:spc24_human(display_long)|uniprotkb:SPBC24(gene name synonym)|uniprotkb:SPC24(gene name)|psi-mi:SPC24(display_short) psi-mi:"MI:0065"(isothermal titration calorimetry) Nishino et al. (2013) pubmed:23334297|imex:IM-22537 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9077845|imex:IM-22537-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079358.3|ensembl:ENSG00000102901(gene)|ensembl:ENST00000440851(transcript)|ensembl:ENST00000562787(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051276"(chromosome organization)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|go:"GO:1903394"(protein localization to kinetochore involved in kinetochore assembly)|interpro:IPR009072(Histone-fold)|interpro:IPR028255|interpro:IPR032373|interpro:IPR035425|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025 refseq:NP_872319.1|ensembl:ENSG00000161888(gene)|ensembl:ENST00000592540(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|mint:Q8NBT2|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_001303960.1|refseq:NP_001303962.1|refseq:XP_005259810.1|dip:DIP-35754N - - - figure legend:sf1h|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:150.0x10^-9 2014/01/08 2014/10/16 rogid:TVIRAvfopdj+sRVaAOHj5xxYssg9606 rogid:ANMEuzMkpwcbiSjx6OaHAK8vVcA9606 intact-crc:FA779040F695CA96|rigid:3h5fhLmMA85P6gyUhlpFebMlQwY false binding-associated region:76-106|mutation increasing interaction:85-85|maltose binding protein tag:?-? binding-associated region:131-197 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96BT3 uniprotkb:Q9HBM1 intact:EBI-719918|uniprotkb:Q96I29|uniprotkb:Q96IC6|uniprotkb:Q96NK9|uniprotkb:Q9H901|ensembl:ENSP00000400140|ensembl:ENSP00000457810 intact:EBI-999909|ensembl:ENSP00000282074|ensembl:ENSP00000481354|ensembl:ENSP00000483050|uniprotkb:D3DPC0|uniprotkb:A8K4X8 psi-mi:cenpt_human(display_long)|uniprotkb:Interphase centromere complex protein 22(gene name synonym)|uniprotkb:CENPT(gene name)|psi-mi:CENPT(display_short)|uniprotkb:C16orf56(gene name synonym)|uniprotkb:ICEN22(gene name synonym) psi-mi:spc25_human(display_long)|uniprotkb:AD024(orf name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short)|uniprotkb:SPBC25(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Nishino et al. (2013) pubmed:23334297|imex:IM-22537 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9077845|imex:IM-22537-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079358.3|ensembl:ENSG00000102901(gene)|ensembl:ENST00000440851(transcript)|ensembl:ENST00000562787(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051276"(chromosome organization)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|go:"GO:1903394"(protein localization to kinetochore involved in kinetochore assembly)|interpro:IPR009072(Histone-fold)|interpro:IPR028255|interpro:IPR032373|interpro:IPR035425|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025 refseq:NP_065726.1|ensembl:ENSG00000277909(gene)|ensembl:ENST00000282074(transcript)|ensembl:ENST00000611144(transcript)|ensembl:ENST00000616584(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|interpro:IPR013255(Kinetochore-Ndc80 subunit Spc25)|mint:Q9HBM1|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENSG00000152253(gene)|dip:DIP-35753N - - - figure legend:sf1h|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:150.0x10^-9 2014/01/08 2014/10/16 rogid:TVIRAvfopdj+sRVaAOHj5xxYssg9606 rogid:qR1LJPKAJwXtOdzKs4Zg0PqJrBM9606 intact-crc:FA779040F695CA96|rigid:3h5fhLmMA85P6gyUhlpFebMlQwY false binding-associated region:76-106|mutation increasing interaction:85-85|maltose binding protein tag:?-? binding-associated region:129-224 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96BT3 uniprotkb:Q8NBT2 intact:EBI-719918|uniprotkb:Q96I29|uniprotkb:Q96IC6|uniprotkb:Q96NK9|uniprotkb:Q9H901|ensembl:ENSP00000400140|ensembl:ENSP00000457810 intact:EBI-999900|uniprotkb:C9JGC4|ensembl:ENSP00000465075|uniprotkb:B4DZZ7 psi-mi:cenpt_human(display_long)|uniprotkb:Interphase centromere complex protein 22(gene name synonym)|uniprotkb:CENPT(gene name)|psi-mi:CENPT(display_short)|uniprotkb:C16orf56(gene name synonym)|uniprotkb:ICEN22(gene name synonym) psi-mi:spc24_human(display_long)|uniprotkb:SPBC24(gene name synonym)|uniprotkb:SPC24(gene name)|psi-mi:SPC24(display_short) psi-mi:"MI:0065"(isothermal titration calorimetry) Nishino et al. (2013) pubmed:23334297|imex:IM-22537 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9077833|imex:IM-22537-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079358.3|ensembl:ENSG00000102901(gene)|ensembl:ENST00000440851(transcript)|ensembl:ENST00000562787(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051276"(chromosome organization)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|go:"GO:1903394"(protein localization to kinetochore involved in kinetochore assembly)|interpro:IPR009072(Histone-fold)|interpro:IPR028255|interpro:IPR032373|interpro:IPR035425|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025 refseq:NP_872319.1|ensembl:ENSG00000161888(gene)|ensembl:ENST00000592540(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|mint:Q8NBT2|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_001303960.1|refseq:NP_001303962.1|refseq:XP_005259810.1|dip:DIP-35754N - - - figure legend:sf1g|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:645.0x10^-9 2014/01/08 2014/10/16 rogid:TVIRAvfopdj+sRVaAOHj5xxYssg9606 rogid:ANMEuzMkpwcbiSjx6OaHAK8vVcA9606 intact-crc:FA7E0040F695CA96|rigid:3h5fhLmMA85P6gyUhlpFebMlQwY false binding-associated region:76-106|maltose binding protein tag:?-? binding-associated region:131-197 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96BT3 uniprotkb:Q9HBM1 intact:EBI-719918|uniprotkb:Q96I29|uniprotkb:Q96IC6|uniprotkb:Q96NK9|uniprotkb:Q9H901|ensembl:ENSP00000400140|ensembl:ENSP00000457810 intact:EBI-999909|ensembl:ENSP00000282074|ensembl:ENSP00000481354|ensembl:ENSP00000483050|uniprotkb:D3DPC0|uniprotkb:A8K4X8 psi-mi:cenpt_human(display_long)|uniprotkb:Interphase centromere complex protein 22(gene name synonym)|uniprotkb:CENPT(gene name)|psi-mi:CENPT(display_short)|uniprotkb:C16orf56(gene name synonym)|uniprotkb:ICEN22(gene name synonym) psi-mi:spc25_human(display_long)|uniprotkb:AD024(orf name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short)|uniprotkb:SPBC25(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Nishino et al. (2013) pubmed:23334297|imex:IM-22537 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9077833|imex:IM-22537-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079358.3|ensembl:ENSG00000102901(gene)|ensembl:ENST00000440851(transcript)|ensembl:ENST00000562787(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051276"(chromosome organization)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|go:"GO:1903394"(protein localization to kinetochore involved in kinetochore assembly)|interpro:IPR009072(Histone-fold)|interpro:IPR028255|interpro:IPR032373|interpro:IPR035425|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025 refseq:NP_065726.1|ensembl:ENSG00000277909(gene)|ensembl:ENST00000282074(transcript)|ensembl:ENST00000611144(transcript)|ensembl:ENST00000616584(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|interpro:IPR013255(Kinetochore-Ndc80 subunit Spc25)|mint:Q9HBM1|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENSG00000152253(gene)|dip:DIP-35753N - - - figure legend:sf1g|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:645.0x10^-9 2014/01/08 2014/10/16 rogid:TVIRAvfopdj+sRVaAOHj5xxYssg9606 rogid:qR1LJPKAJwXtOdzKs4Zg0PqJrBM9606 intact-crc:FA7E0040F695CA96|rigid:3h5fhLmMA85P6gyUhlpFebMlQwY false binding-associated region:76-106|maltose binding protein tag:?-? binding-associated region:129-224 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NG31 uniprotkb:Q9H081 intact:EBI-1001161|intact:EBI-2555927|uniprotkb:Q8NHE1|uniprotkb:Q8WXA6|uniprotkb:Q9HCK2|uniprotkb:Q9NR92|ensembl:ENSP00000335463 intact:EBI-1001205|uniprotkb:Q96N24|ensembl:ENSP00000370557|ensembl:ENSP00000461252|ensembl:ENSP00000484532 psi-mi:knl1_human(display_long)|uniprotkb:KNL1(gene name)|psi-mi:KNL1(display_short)|uniprotkb:ALL1-fused gene from chromosome 15q14 protein(gene name synonym)|uniprotkb:Bub-linking kinetochore protein(gene name synonym)|uniprotkb:CASC5(gene name synonym)|uniprotkb:Cancer susceptibility candidate gene 5 protein(gene name synonym)|uniprotkb:Cancer/testis antigen 29(gene name synonym)|uniprotkb:KIAA1570(gene name synonym)|uniprotkb:Kinetochore-null protein 1(gene name synonym)|uniprotkb:Protein CASC5(gene name synonym)|uniprotkb:Protein D40/AF15q14(gene name synonym) psi-mi:mis12_human(display_long)|uniprotkb:MIS12(gene name)|psi-mi:MIS12(display_short) psi-mi:"MI:0065"(isothermal titration calorimetry) Nishino et al. (2013) pubmed:23334297|imex:IM-22537 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9077911|imex:IM-22537-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000137812(gene)|ensembl:ENST00000346991(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001675"(acrosome assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016604"(nuclear body)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|interpro:IPR037388|interpro:IPR040850|interpro:IPR043651|mint:Q8NG31|rcsb pdb:3SI5|rcsb pdb:4A1G|rcsb pdb:4NF9|rcsb pdb:4NFA|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_653091.3|refseq:NP_733468.3|ensembl:ENSP00000335463|ensembl:ENST00000399668|ensembl:ENSP00000382576|dip:DIP-36474N refseq:NP_001245146.1|refseq:NP_001245147.1|refseq:NP_001245148.1|refseq:NP_001245149.1|refseq:XP_016880522.1|refseq:XP_016880523.1|refseq:XP_016880524.1|refseq:NP_076944.1|ensembl:ENSG00000167842(gene)|ensembl:ENST00000381165(transcript)|ensembl:ENST00000573759(transcript)|ensembl:ENST00000611091(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR008685(Mis12)|mint:Q9H081|rcsb pdb:5LSJ|rcsb pdb:5LSK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-5663220|refseq:XP_005256854.1 - - - figure legend:sf5d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:18.9x10^-9 2014/01/08 2014/10/16 rogid:VrKgxXm7DGkpFhJjZ98oQhkr5Eo9606 rogid:1qNMwDq3AYOWnRnPa2u3yt7O4109606 intact-crc:E91FB55DBEBC948C|rigid:tJQTkZBGCeSsLFtGzu7vg3LBwtY false binding-associated region:2106-2316 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NG31 uniprotkb:Q8NBT2 intact:EBI-1001161|intact:EBI-2555927|uniprotkb:Q8NHE1|uniprotkb:Q8WXA6|uniprotkb:Q9HCK2|uniprotkb:Q9NR92|ensembl:ENSP00000335463 intact:EBI-999900|uniprotkb:C9JGC4|ensembl:ENSP00000465075|uniprotkb:B4DZZ7 psi-mi:knl1_human(display_long)|uniprotkb:KNL1(gene name)|psi-mi:KNL1(display_short)|uniprotkb:ALL1-fused gene from chromosome 15q14 protein(gene name synonym)|uniprotkb:Bub-linking kinetochore protein(gene name synonym)|uniprotkb:CASC5(gene name synonym)|uniprotkb:Cancer susceptibility candidate gene 5 protein(gene name synonym)|uniprotkb:Cancer/testis antigen 29(gene name synonym)|uniprotkb:KIAA1570(gene name synonym)|uniprotkb:Kinetochore-null protein 1(gene name synonym)|uniprotkb:Protein CASC5(gene name synonym)|uniprotkb:Protein D40/AF15q14(gene name synonym) psi-mi:spc24_human(display_long)|uniprotkb:SPBC24(gene name synonym)|uniprotkb:SPC24(gene name)|psi-mi:SPC24(display_short) psi-mi:"MI:0065"(isothermal titration calorimetry) Nishino et al. (2013) pubmed:23334297|imex:IM-22537 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9077911|imex:IM-22537-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000137812(gene)|ensembl:ENST00000346991(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001675"(acrosome assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016604"(nuclear body)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|interpro:IPR037388|interpro:IPR040850|interpro:IPR043651|mint:Q8NG31|rcsb pdb:3SI5|rcsb pdb:4A1G|rcsb pdb:4NF9|rcsb pdb:4NFA|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_653091.3|refseq:NP_733468.3|ensembl:ENSP00000335463|ensembl:ENST00000399668|ensembl:ENSP00000382576|dip:DIP-36474N refseq:NP_872319.1|ensembl:ENSG00000161888(gene)|ensembl:ENST00000592540(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|mint:Q8NBT2|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_001303960.1|refseq:NP_001303962.1|refseq:XP_005259810.1|dip:DIP-35754N - - - figure legend:sf5d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:18.9x10^-9 2014/01/08 2014/10/16 rogid:VrKgxXm7DGkpFhJjZ98oQhkr5Eo9606 rogid:ANMEuzMkpwcbiSjx6OaHAK8vVcA9606 intact-crc:E91FB55DBEBC948C|rigid:tJQTkZBGCeSsLFtGzu7vg3LBwtY false binding-associated region:2106-2316 binding-associated region:57-197 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NG31 uniprotkb:Q9HBM1 intact:EBI-1001161|intact:EBI-2555927|uniprotkb:Q8NHE1|uniprotkb:Q8WXA6|uniprotkb:Q9HCK2|uniprotkb:Q9NR92|ensembl:ENSP00000335463 intact:EBI-999909|ensembl:ENSP00000282074|ensembl:ENSP00000481354|ensembl:ENSP00000483050|uniprotkb:D3DPC0|uniprotkb:A8K4X8 psi-mi:knl1_human(display_long)|uniprotkb:KNL1(gene name)|psi-mi:KNL1(display_short)|uniprotkb:ALL1-fused gene from chromosome 15q14 protein(gene name synonym)|uniprotkb:Bub-linking kinetochore protein(gene name synonym)|uniprotkb:CASC5(gene name synonym)|uniprotkb:Cancer susceptibility candidate gene 5 protein(gene name synonym)|uniprotkb:Cancer/testis antigen 29(gene name synonym)|uniprotkb:KIAA1570(gene name synonym)|uniprotkb:Kinetochore-null protein 1(gene name synonym)|uniprotkb:Protein CASC5(gene name synonym)|uniprotkb:Protein D40/AF15q14(gene name synonym) psi-mi:spc25_human(display_long)|uniprotkb:AD024(orf name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short)|uniprotkb:SPBC25(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Nishino et al. (2013) pubmed:23334297|imex:IM-22537 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9077911|imex:IM-22537-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000137812(gene)|ensembl:ENST00000346991(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001675"(acrosome assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016604"(nuclear body)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|interpro:IPR037388|interpro:IPR040850|interpro:IPR043651|mint:Q8NG31|rcsb pdb:3SI5|rcsb pdb:4A1G|rcsb pdb:4NF9|rcsb pdb:4NFA|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_653091.3|refseq:NP_733468.3|ensembl:ENSP00000335463|ensembl:ENST00000399668|ensembl:ENSP00000382576|dip:DIP-36474N refseq:NP_065726.1|ensembl:ENSG00000277909(gene)|ensembl:ENST00000282074(transcript)|ensembl:ENST00000611144(transcript)|ensembl:ENST00000616584(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|interpro:IPR013255(Kinetochore-Ndc80 subunit Spc25)|mint:Q9HBM1|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENSG00000152253(gene)|dip:DIP-35753N - - - figure legend:sf5d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:18.9x10^-9 2014/01/08 2014/10/16 rogid:VrKgxXm7DGkpFhJjZ98oQhkr5Eo9606 rogid:qR1LJPKAJwXtOdzKs4Zg0PqJrBM9606 intact-crc:E91FB55DBEBC948C|rigid:tJQTkZBGCeSsLFtGzu7vg3LBwtY false binding-associated region:2106-2316 binding-associated region:70-224 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96BT3 uniprotkb:Q8NBT2 intact:EBI-719918|uniprotkb:Q96I29|uniprotkb:Q96IC6|uniprotkb:Q96NK9|uniprotkb:Q9H901|ensembl:ENSP00000400140|ensembl:ENSP00000457810 intact:EBI-999900|uniprotkb:C9JGC4|ensembl:ENSP00000465075|uniprotkb:B4DZZ7 psi-mi:cenpt_human(display_long)|uniprotkb:Interphase centromere complex protein 22(gene name synonym)|uniprotkb:CENPT(gene name)|psi-mi:CENPT(display_short)|uniprotkb:C16orf56(gene name synonym)|uniprotkb:ICEN22(gene name synonym) psi-mi:spc24_human(display_long)|uniprotkb:SPBC24(gene name synonym)|uniprotkb:SPC24(gene name)|psi-mi:SPC24(display_short) psi-mi:"MI:0065"(isothermal titration calorimetry) Nishino et al. (2013) pubmed:23334297|imex:IM-22537 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9077873|imex:IM-22537-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079358.3|ensembl:ENSG00000102901(gene)|ensembl:ENST00000440851(transcript)|ensembl:ENST00000562787(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051276"(chromosome organization)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|go:"GO:1903394"(protein localization to kinetochore involved in kinetochore assembly)|interpro:IPR009072(Histone-fold)|interpro:IPR028255|interpro:IPR032373|interpro:IPR035425|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025 refseq:NP_872319.1|ensembl:ENSG00000161888(gene)|ensembl:ENST00000592540(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|mint:Q8NBT2|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_001303960.1|refseq:NP_001303962.1|refseq:XP_005259810.1|dip:DIP-35754N - - - figure legend:sf5b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:94.0x10^-6 2014/01/08 2014/10/16 rogid:TVIRAvfopdj+sRVaAOHj5xxYssg9606 rogid:ANMEuzMkpwcbiSjx6OaHAK8vVcA9606 intact-crc:3157E7B16A5061D3|rigid:3h5fhLmMA85P6gyUhlpFebMlQwY false binding-associated region:76-106|mutation increasing interaction:85-85|maltose binding protein tag:?-? binding-associated region:57-197 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96BT3 uniprotkb:Q9HBM1 intact:EBI-719918|uniprotkb:Q96I29|uniprotkb:Q96IC6|uniprotkb:Q96NK9|uniprotkb:Q9H901|ensembl:ENSP00000400140|ensembl:ENSP00000457810 intact:EBI-999909|ensembl:ENSP00000282074|ensembl:ENSP00000481354|ensembl:ENSP00000483050|uniprotkb:D3DPC0|uniprotkb:A8K4X8 psi-mi:cenpt_human(display_long)|uniprotkb:Interphase centromere complex protein 22(gene name synonym)|uniprotkb:CENPT(gene name)|psi-mi:CENPT(display_short)|uniprotkb:C16orf56(gene name synonym)|uniprotkb:ICEN22(gene name synonym) psi-mi:spc25_human(display_long)|uniprotkb:AD024(orf name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short)|uniprotkb:SPBC25(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Nishino et al. (2013) pubmed:23334297|imex:IM-22537 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9077873|imex:IM-22537-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079358.3|ensembl:ENSG00000102901(gene)|ensembl:ENST00000440851(transcript)|ensembl:ENST00000562787(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051276"(chromosome organization)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|go:"GO:1903394"(protein localization to kinetochore involved in kinetochore assembly)|interpro:IPR009072(Histone-fold)|interpro:IPR028255|interpro:IPR032373|interpro:IPR035425|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025 refseq:NP_065726.1|ensembl:ENSG00000277909(gene)|ensembl:ENST00000282074(transcript)|ensembl:ENST00000611144(transcript)|ensembl:ENST00000616584(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|interpro:IPR013255(Kinetochore-Ndc80 subunit Spc25)|mint:Q9HBM1|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENSG00000152253(gene)|dip:DIP-35753N - - - figure legend:sf5b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:94.0x10^-6 2014/01/08 2014/10/16 rogid:TVIRAvfopdj+sRVaAOHj5xxYssg9606 rogid:qR1LJPKAJwXtOdzKs4Zg0PqJrBM9606 intact-crc:3157E7B16A5061D3|rigid:3h5fhLmMA85P6gyUhlpFebMlQwY false binding-associated region:76-106|mutation increasing interaction:85-85|maltose binding protein tag:?-? mutation increasing interaction:149-149,154-154|binding-associated region:70-224 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:F1NPG5 uniprotkb:E1C4Y2 intact:EBI-2132248|ensembl:ENSGALP00000042737 intact:EBI-9077663|ensembl:ENSGALP00000017703 psi-mi:cenpt_chick(display_long)|uniprotkb:CENPT(gene name)|psi-mi:CENPT(display_short) psi-mi:e1c4y2_chick(display_long)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short) psi-mi:"MI:0067"(light scattering) Nishino et al. (2013) pubmed:23334297|imex:IM-22537 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9077819|imex:IM-22537-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001263242.1|ensembl:ENSGALG00000028900(gene)|ensembl:ENSGALT00000043964(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:1903394"(protein localization to kinetochore involved in kinetochore assembly)|interpro:IPR009072(Histone-fold)|interpro:IPR028255|interpro:IPR032373|interpro:IPR035425|rcsb pdb:3B0C|rcsb pdb:3B0D|rcsb pdb:3VH5|rcsb pdb:3VH6|rcsb pdb:3VZA refseq:NP_001264786.1|ensembl:ENSGALG00000010900(gene)|ensembl:ENSGALT00000017724(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|interpro:IPR013255(Kinetochore-Ndc80 subunit Spc25)|rcsb pdb:3VZ9|rcsb pdb:3VZA|reactome:R-GGA-141444|reactome:R-GGA-2467813|reactome:R-GGA-2500257|reactome:R-GGA-5663220|reactome:R-GGA-68877|reactome:R-GGA-9648025 - - - figure legend:sf1b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:480.0x10^-9 2014/01/08 2014/10/16 rogid:kRNRHK5vtM8zuKPUe8EHn/G7U6E9031 rogid:7gkfMjZp4vNDoQ9A/RvEzmQD4fA9031 intact-crc:9A3465A05BE0C054|rigid:hscvY2vF89TSLyvzzcBC4YU7L3w false binding-associated region:2-98|maltose binding protein tag:?-? binding-associated region:131-234 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:F1NPG5 uniprotkb:R4GRT4 intact:EBI-2132248|ensembl:ENSGALP00000042737 intact:EBI-9077687 psi-mi:cenpt_chick(display_long)|uniprotkb:CENPT(gene name)|psi-mi:CENPT(display_short) psi-mi:r4grt4_chick(display_long) psi-mi:"MI:0067"(light scattering) Nishino et al. (2013) pubmed:23334297|imex:IM-22537 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9077819|imex:IM-22537-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001263242.1|ensembl:ENSGALG00000028900(gene)|ensembl:ENSGALT00000043964(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:1903394"(protein localization to kinetochore involved in kinetochore assembly)|interpro:IPR009072(Histone-fold)|interpro:IPR028255|interpro:IPR032373|interpro:IPR035425|rcsb pdb:3B0C|rcsb pdb:3B0D|rcsb pdb:3VH5|rcsb pdb:3VH6|rcsb pdb:3VZA interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|rcsb pdb:3VZA|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division) - - - figure legend:sf1b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:480.0x10^-9 2014/01/08 2014/10/16 rogid:kRNRHK5vtM8zuKPUe8EHn/G7U6E9031 rogid:Zg9Z7PzBnhP2OUjOT/1a8rB9RLk9031 intact-crc:9A3465A05BE0C054|rigid:hscvY2vF89TSLyvzzcBC4YU7L3w false binding-associated region:2-98|maltose binding protein tag:?-? - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:F1NPG5 uniprotkb:E1C4Y2 intact:EBI-2132248|ensembl:ENSGALP00000042737 intact:EBI-9077663|ensembl:ENSGALP00000017703 psi-mi:cenpt_chick(display_long)|uniprotkb:CENPT(gene name)|psi-mi:CENPT(display_short) psi-mi:e1c4y2_chick(display_long)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short) psi-mi:"MI:0067"(light scattering) Nishino et al. (2013) pubmed:23334297|imex:IM-22537 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9077805|imex:IM-22537-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001263242.1|ensembl:ENSGALG00000028900(gene)|ensembl:ENSGALT00000043964(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:1903394"(protein localization to kinetochore involved in kinetochore assembly)|interpro:IPR009072(Histone-fold)|interpro:IPR028255|interpro:IPR032373|interpro:IPR035425|rcsb pdb:3B0C|rcsb pdb:3B0D|rcsb pdb:3VH5|rcsb pdb:3VH6|rcsb pdb:3VZA refseq:NP_001264786.1|ensembl:ENSGALG00000010900(gene)|ensembl:ENSGALT00000017724(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|interpro:IPR013255(Kinetochore-Ndc80 subunit Spc25)|rcsb pdb:3VZ9|rcsb pdb:3VZA|reactome:R-GGA-141444|reactome:R-GGA-2467813|reactome:R-GGA-2500257|reactome:R-GGA-5663220|reactome:R-GGA-68877|reactome:R-GGA-9648025 - - - figure legend:f2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:381.0x10^-9 2014/01/08 2014/10/16 rogid:kRNRHK5vtM8zuKPUe8EHn/G7U6E9031 rogid:7gkfMjZp4vNDoQ9A/RvEzmQD4fA9031 intact-crc:FDB2437F635EEDC3|rigid:hscvY2vF89TSLyvzzcBC4YU7L3w false binding-associated region:63-98|mutation decreasing interaction:88-88,72-72|maltose binding protein tag:?-? binding-associated region:132-234 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:F1NPG5 uniprotkb:R4GRT4 intact:EBI-2132248|ensembl:ENSGALP00000042737 intact:EBI-9077687 psi-mi:cenpt_chick(display_long)|uniprotkb:CENPT(gene name)|psi-mi:CENPT(display_short) psi-mi:r4grt4_chick(display_long) psi-mi:"MI:0067"(light scattering) Nishino et al. (2013) pubmed:23334297|imex:IM-22537 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9077805|imex:IM-22537-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001263242.1|ensembl:ENSGALG00000028900(gene)|ensembl:ENSGALT00000043964(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:1903394"(protein localization to kinetochore involved in kinetochore assembly)|interpro:IPR009072(Histone-fold)|interpro:IPR028255|interpro:IPR032373|interpro:IPR035425|rcsb pdb:3B0C|rcsb pdb:3B0D|rcsb pdb:3VH5|rcsb pdb:3VH6|rcsb pdb:3VZA interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|rcsb pdb:3VZA|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division) - - - figure legend:f2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:381.0x10^-9 2014/01/08 2014/10/16 rogid:kRNRHK5vtM8zuKPUe8EHn/G7U6E9031 rogid:Zg9Z7PzBnhP2OUjOT/1a8rB9RLk9031 intact-crc:FDB2437F635EEDC3|rigid:hscvY2vF89TSLyvzzcBC4YU7L3w false binding-associated region:63-98|mutation decreasing interaction:88-88,72-72|maltose binding protein tag:?-? - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:F1NPG5 uniprotkb:E1C4Y2 intact:EBI-2132248|ensembl:ENSGALP00000042737 intact:EBI-9077663|ensembl:ENSGALP00000017703 psi-mi:cenpt_chick(display_long)|uniprotkb:CENPT(gene name)|psi-mi:CENPT(display_short) psi-mi:e1c4y2_chick(display_long)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short) psi-mi:"MI:0071"(molecular sieving) Nishino et al. (2013) pubmed:23334297|imex:IM-22537 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9517836|imex:IM-22537-22 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001263242.1|ensembl:ENSGALG00000028900(gene)|ensembl:ENSGALT00000043964(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:1903394"(protein localization to kinetochore involved in kinetochore assembly)|interpro:IPR009072(Histone-fold)|interpro:IPR028255|interpro:IPR032373|interpro:IPR035425|rcsb pdb:3B0C|rcsb pdb:3B0D|rcsb pdb:3VH5|rcsb pdb:3VH6|rcsb pdb:3VZA refseq:NP_001264786.1|ensembl:ENSGALG00000010900(gene)|ensembl:ENSGALT00000017724(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|interpro:IPR013255(Kinetochore-Ndc80 subunit Spc25)|rcsb pdb:3VZ9|rcsb pdb:3VZA|reactome:R-GGA-141444|reactome:R-GGA-2467813|reactome:R-GGA-2500257|reactome:R-GGA-5663220|reactome:R-GGA-68877|reactome:R-GGA-9648025 - - - figure legend:f4d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/01/08 2014/10/16 rogid:kRNRHK5vtM8zuKPUe8EHn/G7U6E9031 rogid:7gkfMjZp4vNDoQ9A/RvEzmQD4fA9031 intact-crc:1B9B9C8AD56DA8DF|rigid:hscvY2vF89TSLyvzzcBC4YU7L3w false maltose binding protein tag:?-?|binding-associated region:63-98|mutation disrupting interaction:68-68 binding-associated region:131-234 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:F1NPG5 uniprotkb:R4GRT4 intact:EBI-2132248|ensembl:ENSGALP00000042737 intact:EBI-9077687 psi-mi:cenpt_chick(display_long)|uniprotkb:CENPT(gene name)|psi-mi:CENPT(display_short) psi-mi:r4grt4_chick(display_long) psi-mi:"MI:0071"(molecular sieving) Nishino et al. (2013) pubmed:23334297|imex:IM-22537 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9517836|imex:IM-22537-22 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001263242.1|ensembl:ENSGALG00000028900(gene)|ensembl:ENSGALT00000043964(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:1903394"(protein localization to kinetochore involved in kinetochore assembly)|interpro:IPR009072(Histone-fold)|interpro:IPR028255|interpro:IPR032373|interpro:IPR035425|rcsb pdb:3B0C|rcsb pdb:3B0D|rcsb pdb:3VH5|rcsb pdb:3VH6|rcsb pdb:3VZA interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|rcsb pdb:3VZA|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division) - - - figure legend:f4d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/01/08 2014/10/16 rogid:kRNRHK5vtM8zuKPUe8EHn/G7U6E9031 rogid:Zg9Z7PzBnhP2OUjOT/1a8rB9RLk9031 intact-crc:1B9B9C8AD56DA8DF|rigid:hscvY2vF89TSLyvzzcBC4YU7L3w false maltose binding protein tag:?-?|binding-associated region:63-98|mutation disrupting interaction:68-68 - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:F1NPG5 uniprotkb:E1C4Y2 intact:EBI-2132248|ensembl:ENSGALP00000042737 intact:EBI-9077663|ensembl:ENSGALP00000017703 psi-mi:cenpt_chick(display_long)|uniprotkb:CENPT(gene name)|psi-mi:CENPT(display_short) psi-mi:e1c4y2_chick(display_long)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short) psi-mi:"MI:0071"(molecular sieving) Nishino et al. (2013) pubmed:23334297|imex:IM-22537 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9517712|imex:IM-22537-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001263242.1|ensembl:ENSGALG00000028900(gene)|ensembl:ENSGALT00000043964(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:1903394"(protein localization to kinetochore involved in kinetochore assembly)|interpro:IPR009072(Histone-fold)|interpro:IPR028255|interpro:IPR032373|interpro:IPR035425|rcsb pdb:3B0C|rcsb pdb:3B0D|rcsb pdb:3VH5|rcsb pdb:3VH6|rcsb pdb:3VZA refseq:NP_001264786.1|ensembl:ENSGALG00000010900(gene)|ensembl:ENSGALT00000017724(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|interpro:IPR013255(Kinetochore-Ndc80 subunit Spc25)|rcsb pdb:3VZ9|rcsb pdb:3VZA|reactome:R-GGA-141444|reactome:R-GGA-2467813|reactome:R-GGA-2500257|reactome:R-GGA-5663220|reactome:R-GGA-68877|reactome:R-GGA-9648025 - - - figure legend:f2a sf1c f2b f4c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/01/08 2014/10/16 rogid:kRNRHK5vtM8zuKPUe8EHn/G7U6E9031 rogid:7gkfMjZp4vNDoQ9A/RvEzmQD4fA9031 intact-crc:1FB59CA83196FFDA|rigid:hscvY2vF89TSLyvzzcBC4YU7L3w false mutation decreasing interaction:72-72,88-88|binding-associated region:63-98|maltose binding protein tag:?-? binding-associated region:131-234 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:F1NPG5 uniprotkb:R4GRT4 intact:EBI-2132248|ensembl:ENSGALP00000042737 intact:EBI-9077687 psi-mi:cenpt_chick(display_long)|uniprotkb:CENPT(gene name)|psi-mi:CENPT(display_short) psi-mi:r4grt4_chick(display_long) psi-mi:"MI:0071"(molecular sieving) Nishino et al. (2013) pubmed:23334297|imex:IM-22537 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9517712|imex:IM-22537-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001263242.1|ensembl:ENSGALG00000028900(gene)|ensembl:ENSGALT00000043964(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:1903394"(protein localization to kinetochore involved in kinetochore assembly)|interpro:IPR009072(Histone-fold)|interpro:IPR028255|interpro:IPR032373|interpro:IPR035425|rcsb pdb:3B0C|rcsb pdb:3B0D|rcsb pdb:3VH5|rcsb pdb:3VH6|rcsb pdb:3VZA interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|rcsb pdb:3VZA|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division) - - - figure legend:f2a sf1c f2b f4c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/01/08 2014/10/16 rogid:kRNRHK5vtM8zuKPUe8EHn/G7U6E9031 rogid:Zg9Z7PzBnhP2OUjOT/1a8rB9RLk9031 intact-crc:1FB59CA83196FFDA|rigid:hscvY2vF89TSLyvzzcBC4YU7L3w false mutation decreasing interaction:72-72,88-88|binding-associated region:63-98|maltose binding protein tag:?-? - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:F1NPG5 uniprotkb:E1C4Y2 intact:EBI-2132248|ensembl:ENSGALP00000042737 intact:EBI-9077663|ensembl:ENSGALP00000017703 psi-mi:cenpt_chick(display_long)|uniprotkb:CENPT(gene name)|psi-mi:CENPT(display_short) psi-mi:e1c4y2_chick(display_long)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short) psi-mi:"MI:0071"(molecular sieving) Nishino et al. (2013) pubmed:23334297|imex:IM-22537 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9517823|imex:IM-22537-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001263242.1|ensembl:ENSGALG00000028900(gene)|ensembl:ENSGALT00000043964(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:1903394"(protein localization to kinetochore involved in kinetochore assembly)|interpro:IPR009072(Histone-fold)|interpro:IPR028255|interpro:IPR032373|interpro:IPR035425|rcsb pdb:3B0C|rcsb pdb:3B0D|rcsb pdb:3VH5|rcsb pdb:3VH6|rcsb pdb:3VZA refseq:NP_001264786.1|ensembl:ENSGALG00000010900(gene)|ensembl:ENSGALT00000017724(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|interpro:IPR013255(Kinetochore-Ndc80 subunit Spc25)|rcsb pdb:3VZ9|rcsb pdb:3VZA|reactome:R-GGA-141444|reactome:R-GGA-2467813|reactome:R-GGA-2500257|reactome:R-GGA-5663220|reactome:R-GGA-68877|reactome:R-GGA-9648025 - - - figure legend:f4c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/01/08 2014/10/16 rogid:kRNRHK5vtM8zuKPUe8EHn/G7U6E9031 rogid:7gkfMjZp4vNDoQ9A/RvEzmQD4fA9031 intact-crc:59D32AF7B29EE04E|rigid:hscvY2vF89TSLyvzzcBC4YU7L3w false mutation disrupting interaction:74-74|binding-associated region:63-98|maltose binding protein tag:?-? binding-associated region:131-234 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:F1NPG5 uniprotkb:R4GRT4 intact:EBI-2132248|ensembl:ENSGALP00000042737 intact:EBI-9077687 psi-mi:cenpt_chick(display_long)|uniprotkb:CENPT(gene name)|psi-mi:CENPT(display_short) psi-mi:r4grt4_chick(display_long) psi-mi:"MI:0071"(molecular sieving) Nishino et al. (2013) pubmed:23334297|imex:IM-22537 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9517823|imex:IM-22537-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001263242.1|ensembl:ENSGALG00000028900(gene)|ensembl:ENSGALT00000043964(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:1903394"(protein localization to kinetochore involved in kinetochore assembly)|interpro:IPR009072(Histone-fold)|interpro:IPR028255|interpro:IPR032373|interpro:IPR035425|rcsb pdb:3B0C|rcsb pdb:3B0D|rcsb pdb:3VH5|rcsb pdb:3VH6|rcsb pdb:3VZA interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|rcsb pdb:3VZA|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division) - - - figure legend:f4c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/01/08 2014/10/16 rogid:kRNRHK5vtM8zuKPUe8EHn/G7U6E9031 rogid:Zg9Z7PzBnhP2OUjOT/1a8rB9RLk9031 intact-crc:59D32AF7B29EE04E|rigid:hscvY2vF89TSLyvzzcBC4YU7L3w false mutation disrupting interaction:74-74|binding-associated region:63-98|maltose binding protein tag:?-? - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:F1NPG5 uniprotkb:E1C4Y2 intact:EBI-2132248|ensembl:ENSGALP00000042737 intact:EBI-9077663|ensembl:ENSGALP00000017703 psi-mi:cenpt_chick(display_long)|uniprotkb:CENPT(gene name)|psi-mi:CENPT(display_short) psi-mi:e1c4y2_chick(display_long)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short) psi-mi:"MI:0071"(molecular sieving) Nishino et al. (2013) pubmed:23334297|imex:IM-22537 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9517809|imex:IM-22537-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001263242.1|ensembl:ENSGALG00000028900(gene)|ensembl:ENSGALT00000043964(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:1903394"(protein localization to kinetochore involved in kinetochore assembly)|interpro:IPR009072(Histone-fold)|interpro:IPR028255|interpro:IPR032373|interpro:IPR035425|rcsb pdb:3B0C|rcsb pdb:3B0D|rcsb pdb:3VH5|rcsb pdb:3VH6|rcsb pdb:3VZA refseq:NP_001264786.1|ensembl:ENSGALG00000010900(gene)|ensembl:ENSGALT00000017724(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|interpro:IPR013255(Kinetochore-Ndc80 subunit Spc25)|rcsb pdb:3VZ9|rcsb pdb:3VZA|reactome:R-GGA-141444|reactome:R-GGA-2467813|reactome:R-GGA-2500257|reactome:R-GGA-5663220|reactome:R-GGA-68877|reactome:R-GGA-9648025 - - - figure legend:f4c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/01/08 2014/10/16 rogid:kRNRHK5vtM8zuKPUe8EHn/G7U6E9031 rogid:7gkfMjZp4vNDoQ9A/RvEzmQD4fA9031 intact-crc:6D5159D57941B64C|rigid:hscvY2vF89TSLyvzzcBC4YU7L3w false maltose binding protein tag:?-?|binding-associated region:63-98|mutation disrupting interaction:74-74 binding-associated region:131-234 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:F1NPG5 uniprotkb:R4GRT4 intact:EBI-2132248|ensembl:ENSGALP00000042737 intact:EBI-9077687 psi-mi:cenpt_chick(display_long)|uniprotkb:CENPT(gene name)|psi-mi:CENPT(display_short) psi-mi:r4grt4_chick(display_long) psi-mi:"MI:0071"(molecular sieving) Nishino et al. (2013) pubmed:23334297|imex:IM-22537 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9517809|imex:IM-22537-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001263242.1|ensembl:ENSGALG00000028900(gene)|ensembl:ENSGALT00000043964(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:1903394"(protein localization to kinetochore involved in kinetochore assembly)|interpro:IPR009072(Histone-fold)|interpro:IPR028255|interpro:IPR032373|interpro:IPR035425|rcsb pdb:3B0C|rcsb pdb:3B0D|rcsb pdb:3VH5|rcsb pdb:3VH6|rcsb pdb:3VZA interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|rcsb pdb:3VZA|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division) - - - figure legend:f4c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/01/08 2014/10/16 rogid:kRNRHK5vtM8zuKPUe8EHn/G7U6E9031 rogid:Zg9Z7PzBnhP2OUjOT/1a8rB9RLk9031 intact-crc:6D5159D57941B64C|rigid:hscvY2vF89TSLyvzzcBC4YU7L3w false maltose binding protein tag:?-?|binding-associated region:63-98|mutation disrupting interaction:74-74 - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9H410 uniprotkb:Q8NG31 intact:EBI-1001144|uniprotkb:E1P5U9|uniprotkb:Q5JW56|uniprotkb:Q9H8P4|ensembl:ENSP00000362855|ensembl:ENSP00000389810|uniprotkb:Q5JW55|uniprotkb:B4DWT2 intact:EBI-1001161|intact:EBI-2555927|uniprotkb:Q8NHE1|uniprotkb:Q8WXA6|uniprotkb:Q9HCK2|uniprotkb:Q9NR92|ensembl:ENSP00000335463 psi-mi:dsn1_human(display_long)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)|uniprotkb:C20orf172(gene name synonym)|uniprotkb:MIS13(gene name synonym) psi-mi:knl1_human(display_long)|uniprotkb:KNL1(gene name)|psi-mi:KNL1(display_short)|uniprotkb:ALL1-fused gene from chromosome 15q14 protein(gene name synonym)|uniprotkb:Bub-linking kinetochore protein(gene name synonym)|uniprotkb:CASC5(gene name synonym)|uniprotkb:Cancer susceptibility candidate gene 5 protein(gene name synonym)|uniprotkb:Cancer/testis antigen 29(gene name synonym)|uniprotkb:KIAA1570(gene name synonym)|uniprotkb:Kinetochore-null protein 1(gene name synonym)|uniprotkb:Protein CASC5(gene name synonym)|uniprotkb:Protein D40/AF15q14(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Nishino et al. (2013) pubmed:23334297|imex:IM-22537 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9517794|imex:IM-22537-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138789.1|refseq:NP_001138787.1|refseq:NP_001138788.1|refseq:NP_079194.3|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-68877|reactome:R-HSA-9648025|rcsb pdb:5LSK|ensembl:ENSG00000149636(gene)|ensembl:ENST00000373750(transcript)|ensembl:ENST00000426836(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000939"(inner kinetochore)|go:"GO:0001650"(fibrillar center)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0051301"(cell division)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|mint:Q9H410|rcsb pdb:5LSI|rcsb pdb:5LSJ|refseq:NP_001138790.1|refseq:XP_006723939.1 ensembl:ENSG00000137812(gene)|ensembl:ENST00000346991(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001675"(acrosome assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016604"(nuclear body)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|interpro:IPR037388|interpro:IPR040850|interpro:IPR043651|mint:Q8NG31|rcsb pdb:3SI5|rcsb pdb:4A1G|rcsb pdb:4NF9|rcsb pdb:4NFA|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_653091.3|refseq:NP_733468.3|ensembl:ENSP00000335463|ensembl:ENST00000399668|ensembl:ENSP00000382576|dip:DIP-36474N - - - figure legend:sf2c f5d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/01/08 2014/10/16 rogid:cJ0wCtpLS+YkMj83k/SubkpHwuE9606 rogid:VrKgxXm7DGkpFhJjZ98oQhkr5Eo9606 intact-crc:64EFFD1D2285C0D4|rigid:RKO7CW1pcP252q5VN/PVeAY5BN0 false - binding-associated region:2106-2316 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9H410 uniprotkb:Q9H081 intact:EBI-1001144|uniprotkb:E1P5U9|uniprotkb:Q5JW56|uniprotkb:Q9H8P4|ensembl:ENSP00000362855|ensembl:ENSP00000389810|uniprotkb:Q5JW55|uniprotkb:B4DWT2 intact:EBI-1001205|uniprotkb:Q96N24|ensembl:ENSP00000370557|ensembl:ENSP00000461252|ensembl:ENSP00000484532 psi-mi:dsn1_human(display_long)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)|uniprotkb:C20orf172(gene name synonym)|uniprotkb:MIS13(gene name synonym) psi-mi:mis12_human(display_long)|uniprotkb:MIS12(gene name)|psi-mi:MIS12(display_short) psi-mi:"MI:0071"(molecular sieving) Nishino et al. (2013) pubmed:23334297|imex:IM-22537 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9517794|imex:IM-22537-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138789.1|refseq:NP_001138787.1|refseq:NP_001138788.1|refseq:NP_079194.3|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-68877|reactome:R-HSA-9648025|rcsb pdb:5LSK|ensembl:ENSG00000149636(gene)|ensembl:ENST00000373750(transcript)|ensembl:ENST00000426836(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000939"(inner kinetochore)|go:"GO:0001650"(fibrillar center)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0051301"(cell division)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|mint:Q9H410|rcsb pdb:5LSI|rcsb pdb:5LSJ|refseq:NP_001138790.1|refseq:XP_006723939.1 refseq:NP_001245146.1|refseq:NP_001245147.1|refseq:NP_001245148.1|refseq:NP_001245149.1|refseq:XP_016880522.1|refseq:XP_016880523.1|refseq:XP_016880524.1|refseq:NP_076944.1|ensembl:ENSG00000167842(gene)|ensembl:ENST00000381165(transcript)|ensembl:ENST00000573759(transcript)|ensembl:ENST00000611091(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR008685(Mis12)|mint:Q9H081|rcsb pdb:5LSJ|rcsb pdb:5LSK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-5663220|refseq:XP_005256854.1 - - - figure legend:sf2c f5d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/01/08 2014/10/16 rogid:cJ0wCtpLS+YkMj83k/SubkpHwuE9606 rogid:1qNMwDq3AYOWnRnPa2u3yt7O4109606 intact-crc:64EFFD1D2285C0D4|rigid:RKO7CW1pcP252q5VN/PVeAY5BN0 false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9H410 uniprotkb:Q96IY1 intact:EBI-1001144|uniprotkb:E1P5U9|uniprotkb:Q5JW56|uniprotkb:Q9H8P4|ensembl:ENSP00000362855|ensembl:ENSP00000389810|uniprotkb:Q5JW55|uniprotkb:B4DWT2 intact:EBI-2554690|uniprotkb:Q9H2M5|uniprotkb:Q5SY75|uniprotkb:Q9Y415|uniprotkb:Q9NRN8|ensembl:ENSP00000355944|uniprotkb:E7ETD5 psi-mi:dsn1_human(display_long)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)|uniprotkb:C20orf172(gene name synonym)|uniprotkb:MIS13(gene name synonym) psi-mi:nsl1_human(display_long)|uniprotkb:C1orf48(gene name synonym)|uniprotkb:DC8(orf name)|uniprotkb:DC31(orf name)|uniprotkb:MIS14(orf name)|uniprotkb:NSL1(gene name)|psi-mi:NSL1(display_short) psi-mi:"MI:0071"(molecular sieving) Nishino et al. (2013) pubmed:23334297|imex:IM-22537 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9517794|imex:IM-22537-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138789.1|refseq:NP_001138787.1|refseq:NP_001138788.1|refseq:NP_079194.3|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-68877|reactome:R-HSA-9648025|rcsb pdb:5LSK|ensembl:ENSG00000149636(gene)|ensembl:ENST00000373750(transcript)|ensembl:ENST00000426836(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000939"(inner kinetochore)|go:"GO:0001650"(fibrillar center)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0051301"(cell division)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|mint:Q9H410|rcsb pdb:5LSI|rcsb pdb:5LSJ|refseq:NP_001138790.1|refseq:XP_006723939.1 refseq:NP_056286.3|ensembl:ENSG00000117697(gene)|ensembl:ENST00000366977(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0005829"(cytosol)|go:"GO:0016607"(nuclear speck)|go:"GO:0051301"(cell division)|interpro:IPR013950(Kinetochore Mis14)|mint:Q96IY1|rcsb pdb:4NF9|rcsb pdb:5LSI|rcsb pdb:5LSJ|rcsb pdb:5LSK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-2500257|reactome:R-HSA-9648025|refseq:NP_001036014.1 - - - figure legend:sf2c f5d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/01/08 2014/10/16 rogid:cJ0wCtpLS+YkMj83k/SubkpHwuE9606 rogid:w4K2MEHLfZvFECNhtDanXWF0LQk9606 intact-crc:64EFFD1D2285C0D4|rigid:RKO7CW1pcP252q5VN/PVeAY5BN0 false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q96BT3 uniprotkb:Q8NBT2 intact:EBI-719918|uniprotkb:Q96I29|uniprotkb:Q96IC6|uniprotkb:Q96NK9|uniprotkb:Q9H901|ensembl:ENSP00000400140|ensembl:ENSP00000457810 intact:EBI-999900|uniprotkb:C9JGC4|ensembl:ENSP00000465075|uniprotkb:B4DZZ7 psi-mi:cenpt_human(display_long)|uniprotkb:Interphase centromere complex protein 22(gene name synonym)|uniprotkb:CENPT(gene name)|psi-mi:CENPT(display_short)|uniprotkb:C16orf56(gene name synonym)|uniprotkb:ICEN22(gene name synonym) psi-mi:spc24_human(display_long)|uniprotkb:SPBC24(gene name synonym)|uniprotkb:SPC24(gene name)|psi-mi:SPC24(display_short) psi-mi:"MI:0071"(molecular sieving) Nishino et al. (2013) pubmed:23334297|imex:IM-22537 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9517729|imex:IM-22537-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079358.3|ensembl:ENSG00000102901(gene)|ensembl:ENST00000440851(transcript)|ensembl:ENST00000562787(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051276"(chromosome organization)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|go:"GO:1903394"(protein localization to kinetochore involved in kinetochore assembly)|interpro:IPR009072(Histone-fold)|interpro:IPR028255|interpro:IPR032373|interpro:IPR035425|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025 refseq:NP_872319.1|ensembl:ENSG00000161888(gene)|ensembl:ENST00000592540(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|mint:Q8NBT2|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_001303960.1|refseq:NP_001303962.1|refseq:XP_005259810.1|dip:DIP-35754N - - - figure legend:sf1f sf1e sf5a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/01/08 2014/10/16 rogid:TVIRAvfopdj+sRVaAOHj5xxYssg9606 rogid:ANMEuzMkpwcbiSjx6OaHAK8vVcA9606 intact-crc:3F0AEDEE4040B5A5|rigid:3h5fhLmMA85P6gyUhlpFebMlQwY false binding-associated region:76-106|maltose binding protein tag:?-?|mutation increasing interaction:85-85 binding-associated region:131-197 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q96BT3 uniprotkb:Q9HBM1 intact:EBI-719918|uniprotkb:Q96I29|uniprotkb:Q96IC6|uniprotkb:Q96NK9|uniprotkb:Q9H901|ensembl:ENSP00000400140|ensembl:ENSP00000457810 intact:EBI-999909|ensembl:ENSP00000282074|ensembl:ENSP00000481354|ensembl:ENSP00000483050|uniprotkb:D3DPC0|uniprotkb:A8K4X8 psi-mi:cenpt_human(display_long)|uniprotkb:Interphase centromere complex protein 22(gene name synonym)|uniprotkb:CENPT(gene name)|psi-mi:CENPT(display_short)|uniprotkb:C16orf56(gene name synonym)|uniprotkb:ICEN22(gene name synonym) psi-mi:spc25_human(display_long)|uniprotkb:AD024(orf name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short)|uniprotkb:SPBC25(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Nishino et al. (2013) pubmed:23334297|imex:IM-22537 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9517729|imex:IM-22537-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079358.3|ensembl:ENSG00000102901(gene)|ensembl:ENST00000440851(transcript)|ensembl:ENST00000562787(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051276"(chromosome organization)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|go:"GO:1903394"(protein localization to kinetochore involved in kinetochore assembly)|interpro:IPR009072(Histone-fold)|interpro:IPR028255|interpro:IPR032373|interpro:IPR035425|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025 refseq:NP_065726.1|ensembl:ENSG00000277909(gene)|ensembl:ENST00000282074(transcript)|ensembl:ENST00000611144(transcript)|ensembl:ENST00000616584(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|interpro:IPR013255(Kinetochore-Ndc80 subunit Spc25)|mint:Q9HBM1|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENSG00000152253(gene)|dip:DIP-35753N - - - figure legend:sf1f sf1e sf5a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/01/08 2014/10/16 rogid:TVIRAvfopdj+sRVaAOHj5xxYssg9606 rogid:qR1LJPKAJwXtOdzKs4Zg0PqJrBM9606 intact-crc:3F0AEDEE4040B5A5|rigid:3h5fhLmMA85P6gyUhlpFebMlQwY false binding-associated region:76-106|maltose binding protein tag:?-?|mutation increasing interaction:85-85 mutation disrupting interaction:149-149,154-154|binding-associated region:129-224 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q8NG31 uniprotkb:Q9H081 intact:EBI-1001161|intact:EBI-2555927|uniprotkb:Q8NHE1|uniprotkb:Q8WXA6|uniprotkb:Q9HCK2|uniprotkb:Q9NR92|ensembl:ENSP00000335463 intact:EBI-1001205|uniprotkb:Q96N24|ensembl:ENSP00000370557|ensembl:ENSP00000461252|ensembl:ENSP00000484532 psi-mi:knl1_human(display_long)|uniprotkb:KNL1(gene name)|psi-mi:KNL1(display_short)|uniprotkb:ALL1-fused gene from chromosome 15q14 protein(gene name synonym)|uniprotkb:Bub-linking kinetochore protein(gene name synonym)|uniprotkb:CASC5(gene name synonym)|uniprotkb:Cancer susceptibility candidate gene 5 protein(gene name synonym)|uniprotkb:Cancer/testis antigen 29(gene name synonym)|uniprotkb:KIAA1570(gene name synonym)|uniprotkb:Kinetochore-null protein 1(gene name synonym)|uniprotkb:Protein CASC5(gene name synonym)|uniprotkb:Protein D40/AF15q14(gene name synonym) psi-mi:mis12_human(display_long)|uniprotkb:MIS12(gene name)|psi-mi:MIS12(display_short) psi-mi:"MI:0071"(molecular sieving) Nishino et al. (2013) pubmed:23334297|imex:IM-22537 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9517774|imex:IM-22537-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000137812(gene)|ensembl:ENST00000346991(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001675"(acrosome assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016604"(nuclear body)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|interpro:IPR037388|interpro:IPR040850|interpro:IPR043651|mint:Q8NG31|rcsb pdb:3SI5|rcsb pdb:4A1G|rcsb pdb:4NF9|rcsb pdb:4NFA|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_653091.3|refseq:NP_733468.3|ensembl:ENSP00000335463|ensembl:ENST00000399668|ensembl:ENSP00000382576|dip:DIP-36474N refseq:NP_001245146.1|refseq:NP_001245147.1|refseq:NP_001245148.1|refseq:NP_001245149.1|refseq:XP_016880522.1|refseq:XP_016880523.1|refseq:XP_016880524.1|refseq:NP_076944.1|ensembl:ENSG00000167842(gene)|ensembl:ENST00000381165(transcript)|ensembl:ENST00000573759(transcript)|ensembl:ENST00000611091(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR008685(Mis12)|mint:Q9H081|rcsb pdb:5LSJ|rcsb pdb:5LSK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-5663220|refseq:XP_005256854.1 - - - figure legend:sf5e sf5c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/01/08 2014/10/16 rogid:VrKgxXm7DGkpFhJjZ98oQhkr5Eo9606 rogid:1qNMwDq3AYOWnRnPa2u3yt7O4109606 intact-crc:A070C2EE3D0E1140|rigid:tJQTkZBGCeSsLFtGzu7vg3LBwtY false binding-associated region:2106-2316 - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q8NG31 uniprotkb:Q8NBT2 intact:EBI-1001161|intact:EBI-2555927|uniprotkb:Q8NHE1|uniprotkb:Q8WXA6|uniprotkb:Q9HCK2|uniprotkb:Q9NR92|ensembl:ENSP00000335463 intact:EBI-999900|uniprotkb:C9JGC4|ensembl:ENSP00000465075|uniprotkb:B4DZZ7 psi-mi:knl1_human(display_long)|uniprotkb:KNL1(gene name)|psi-mi:KNL1(display_short)|uniprotkb:ALL1-fused gene from chromosome 15q14 protein(gene name synonym)|uniprotkb:Bub-linking kinetochore protein(gene name synonym)|uniprotkb:CASC5(gene name synonym)|uniprotkb:Cancer susceptibility candidate gene 5 protein(gene name synonym)|uniprotkb:Cancer/testis antigen 29(gene name synonym)|uniprotkb:KIAA1570(gene name synonym)|uniprotkb:Kinetochore-null protein 1(gene name synonym)|uniprotkb:Protein CASC5(gene name synonym)|uniprotkb:Protein D40/AF15q14(gene name synonym) psi-mi:spc24_human(display_long)|uniprotkb:SPBC24(gene name synonym)|uniprotkb:SPC24(gene name)|psi-mi:SPC24(display_short) psi-mi:"MI:0071"(molecular sieving) Nishino et al. (2013) pubmed:23334297|imex:IM-22537 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9517774|imex:IM-22537-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000137812(gene)|ensembl:ENST00000346991(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001675"(acrosome assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016604"(nuclear body)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|interpro:IPR037388|interpro:IPR040850|interpro:IPR043651|mint:Q8NG31|rcsb pdb:3SI5|rcsb pdb:4A1G|rcsb pdb:4NF9|rcsb pdb:4NFA|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_653091.3|refseq:NP_733468.3|ensembl:ENSP00000335463|ensembl:ENST00000399668|ensembl:ENSP00000382576|dip:DIP-36474N refseq:NP_872319.1|ensembl:ENSG00000161888(gene)|ensembl:ENST00000592540(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|mint:Q8NBT2|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_001303960.1|refseq:NP_001303962.1|refseq:XP_005259810.1|dip:DIP-35754N - - - figure legend:sf5e sf5c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/01/08 2014/10/16 rogid:VrKgxXm7DGkpFhJjZ98oQhkr5Eo9606 rogid:ANMEuzMkpwcbiSjx6OaHAK8vVcA9606 intact-crc:A070C2EE3D0E1140|rigid:tJQTkZBGCeSsLFtGzu7vg3LBwtY false binding-associated region:2106-2316 binding-associated region:57-197 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q8NG31 uniprotkb:Q9HBM1 intact:EBI-1001161|intact:EBI-2555927|uniprotkb:Q8NHE1|uniprotkb:Q8WXA6|uniprotkb:Q9HCK2|uniprotkb:Q9NR92|ensembl:ENSP00000335463 intact:EBI-999909|ensembl:ENSP00000282074|ensembl:ENSP00000481354|ensembl:ENSP00000483050|uniprotkb:D3DPC0|uniprotkb:A8K4X8 psi-mi:knl1_human(display_long)|uniprotkb:KNL1(gene name)|psi-mi:KNL1(display_short)|uniprotkb:ALL1-fused gene from chromosome 15q14 protein(gene name synonym)|uniprotkb:Bub-linking kinetochore protein(gene name synonym)|uniprotkb:CASC5(gene name synonym)|uniprotkb:Cancer susceptibility candidate gene 5 protein(gene name synonym)|uniprotkb:Cancer/testis antigen 29(gene name synonym)|uniprotkb:KIAA1570(gene name synonym)|uniprotkb:Kinetochore-null protein 1(gene name synonym)|uniprotkb:Protein CASC5(gene name synonym)|uniprotkb:Protein D40/AF15q14(gene name synonym) psi-mi:spc25_human(display_long)|uniprotkb:AD024(orf name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short)|uniprotkb:SPBC25(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Nishino et al. (2013) pubmed:23334297|imex:IM-22537 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-9517774|imex:IM-22537-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000137812(gene)|ensembl:ENST00000346991(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001675"(acrosome assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016604"(nuclear body)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|interpro:IPR037388|interpro:IPR040850|interpro:IPR043651|mint:Q8NG31|rcsb pdb:3SI5|rcsb pdb:4A1G|rcsb pdb:4NF9|rcsb pdb:4NFA|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_653091.3|refseq:NP_733468.3|ensembl:ENSP00000335463|ensembl:ENST00000399668|ensembl:ENSP00000382576|dip:DIP-36474N refseq:NP_065726.1|ensembl:ENSG00000277909(gene)|ensembl:ENST00000282074(transcript)|ensembl:ENST00000611144(transcript)|ensembl:ENST00000616584(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|interpro:IPR013255(Kinetochore-Ndc80 subunit Spc25)|mint:Q9HBM1|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENSG00000152253(gene)|dip:DIP-35753N - - - figure legend:sf5e sf5c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/01/08 2014/10/16 rogid:VrKgxXm7DGkpFhJjZ98oQhkr5Eo9606 rogid:qR1LJPKAJwXtOdzKs4Zg0PqJrBM9606 intact-crc:A070C2EE3D0E1140|rigid:tJQTkZBGCeSsLFtGzu7vg3LBwtY false binding-associated region:2106-2316 binding-associated region:70-224 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)