#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P43618	uniprotkb:Q04477	intact:EBI-23036|uniprotkb:D6VTS9|uniprotkb:Q6B2K8|ensemblfungi:YFR046C	intact:EBI-27228|uniprotkb:D6VZU0|ensemblfungi:YMR117C	psi-mi:cenpt_yeast(display_long)|uniprotkb:CNN1(gene name)|psi-mi:CNN1(display_short)|uniprotkb:Co-purified with NNF1 protein 1(gene name synonym)|uniprotkb:CENP-T homolog(gene name synonym)|uniprotkb:Constitutive centromere-associated network protein CNN1(gene name synonym)|uniprotkb:YFR046C(locus name)	psi-mi:spc24_yeast(display_long)|uniprotkb:SPC24(gene name)|psi-mi:SPC24(display_short)|uniprotkb:YM9718.16C(orf name)|uniprotkb:YMR117C(locus name)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Malvezzi et al. (2013)	pubmed:23334295|imex:IM-22196	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9076094|imex:IM-22196-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001942|refseq:NP_116704.1|dip:DIP-5186N|ensemblfungi:YFR046C(gene)|ensemblfungi:YFR046C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:1901720"(negative regulation of NMS complex assembly)|rcsb pdb:4GEQ|rcsb pdb:6WUC|rcsb pdb:6YPC	refseq:NP_013835.1|sgd:S000004723|mint:Q04477|dip:DIP-893N|ensemblfungi:YMR117C(gene)|ensemblfungi:YMR117C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF	-	crc64:48CEEC087A056D42	crc64:8BE4B8619DD4C8FB	figure legend:f1b f3c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:3.5x10^-6(molar)	2014/01/07	2014/10/16	rogid:Pkvt7uOWT2WqZlcWh8NeZH67Mvs559292	rogid:B12w0JvNs2He1WjK6c241nF3pZc559292	intact-crc:27D58E8CF84B1A94|rigid:/GG1YCjvGaMSXVZOMBYLsFt20Gk	false	binding-associated region:60-84	binding-associated region:155-213	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43618	uniprotkb:P40014	intact:EBI-23036|uniprotkb:D6VTS9|uniprotkb:Q6B2K8|ensemblfungi:YFR046C	intact:EBI-22458|uniprotkb:D3DLR6|ensemblfungi:YER018C	psi-mi:cenpt_yeast(display_long)|uniprotkb:CNN1(gene name)|psi-mi:CNN1(display_short)|uniprotkb:Co-purified with NNF1 protein 1(gene name synonym)|uniprotkb:CENP-T homolog(gene name synonym)|uniprotkb:Constitutive centromere-associated network protein CNN1(gene name synonym)|uniprotkb:YFR046C(locus name)	psi-mi:spc25_yeast(display_long)|uniprotkb:YER018C(locus name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Malvezzi et al. (2013)	pubmed:23334295|imex:IM-22196	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9076094|imex:IM-22196-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001942|refseq:NP_116704.1|dip:DIP-5186N|ensemblfungi:YFR046C(gene)|ensemblfungi:YFR046C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:1901720"(negative regulation of NMS complex assembly)|rcsb pdb:4GEQ|rcsb pdb:6WUC|rcsb pdb:6YPC	refseq:NP_010934.3|sgd:S000000820|dip:DIP-2990N|mint:P40014|ensemblfungi:YER018C(gene)|ensemblfungi:YER018C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF	-	crc64:48CEEC087A056D42	crc64:1BED6CCFF330A5D8	figure legend:f1b f3c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:3.5x10^-6(molar)	2014/01/07	2014/10/16	rogid:Pkvt7uOWT2WqZlcWh8NeZH67Mvs559292	rogid:i5gKRZA7GAjnCVzuX/qP8YmpQRA559292	intact-crc:27D58E8CF84B1A94|rigid:/GG1YCjvGaMSXVZOMBYLsFt20Gk	false	binding-associated region:60-84	binding-associated region:133-221|mutation disrupting interaction:159-159	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43618	uniprotkb:Q04477	intact:EBI-23036|uniprotkb:D6VTS9|uniprotkb:Q6B2K8|ensemblfungi:YFR046C	intact:EBI-27228|uniprotkb:D6VZU0|ensemblfungi:YMR117C	psi-mi:cenpt_yeast(display_long)|uniprotkb:CNN1(gene name)|psi-mi:CNN1(display_short)|uniprotkb:Co-purified with NNF1 protein 1(gene name synonym)|uniprotkb:CENP-T homolog(gene name synonym)|uniprotkb:Constitutive centromere-associated network protein CNN1(gene name synonym)|uniprotkb:YFR046C(locus name)	psi-mi:spc24_yeast(display_long)|uniprotkb:SPC24(gene name)|psi-mi:SPC24(display_short)|uniprotkb:YM9718.16C(orf name)|uniprotkb:YMR117C(locus name)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Malvezzi et al. (2013)	pubmed:23334295|imex:IM-22196	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9076287|imex:IM-22196-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001942|refseq:NP_116704.1|dip:DIP-5186N|ensemblfungi:YFR046C(gene)|ensemblfungi:YFR046C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:1901720"(negative regulation of NMS complex assembly)|rcsb pdb:4GEQ|rcsb pdb:6WUC|rcsb pdb:6YPC	refseq:NP_013835.1|sgd:S000004723|mint:Q04477|dip:DIP-893N|ensemblfungi:YMR117C(gene)|ensemblfungi:YMR117C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF	-	crc64:48CEEC087A056D42	crc64:8BE4B8619DD4C8FB	figure legend:f1b f3c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:3.5x10^-6(molar)	2014/01/07	2014/10/16	rogid:Pkvt7uOWT2WqZlcWh8NeZH67Mvs559292	rogid:B12w0JvNs2He1WjK6c241nF3pZc559292	intact-crc:D15FF59A612855B0|rigid:/GG1YCjvGaMSXVZOMBYLsFt20Gk	false	binding-associated region:60-84	binding-associated region:155-213|mutation disrupting interaction:160-160	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43618	uniprotkb:P40014	intact:EBI-23036|uniprotkb:D6VTS9|uniprotkb:Q6B2K8|ensemblfungi:YFR046C	intact:EBI-22458|uniprotkb:D3DLR6|ensemblfungi:YER018C	psi-mi:cenpt_yeast(display_long)|uniprotkb:CNN1(gene name)|psi-mi:CNN1(display_short)|uniprotkb:Co-purified with NNF1 protein 1(gene name synonym)|uniprotkb:CENP-T homolog(gene name synonym)|uniprotkb:Constitutive centromere-associated network protein CNN1(gene name synonym)|uniprotkb:YFR046C(locus name)	psi-mi:spc25_yeast(display_long)|uniprotkb:YER018C(locus name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Malvezzi et al. (2013)	pubmed:23334295|imex:IM-22196	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9076287|imex:IM-22196-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001942|refseq:NP_116704.1|dip:DIP-5186N|ensemblfungi:YFR046C(gene)|ensemblfungi:YFR046C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:1901720"(negative regulation of NMS complex assembly)|rcsb pdb:4GEQ|rcsb pdb:6WUC|rcsb pdb:6YPC	refseq:NP_010934.3|sgd:S000000820|dip:DIP-2990N|mint:P40014|ensemblfungi:YER018C(gene)|ensemblfungi:YER018C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF	-	crc64:48CEEC087A056D42	crc64:1BED6CCFF330A5D8	figure legend:f1b f3c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:3.5x10^-6(molar)	2014/01/07	2014/10/16	rogid:Pkvt7uOWT2WqZlcWh8NeZH67Mvs559292	rogid:i5gKRZA7GAjnCVzuX/qP8YmpQRA559292	intact-crc:D15FF59A612855B0|rigid:/GG1YCjvGaMSXVZOMBYLsFt20Gk	false	binding-associated region:60-84	binding-associated region:133-221	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43618	uniprotkb:Q04477	intact:EBI-23036|uniprotkb:D6VTS9|uniprotkb:Q6B2K8|ensemblfungi:YFR046C	intact:EBI-27228|uniprotkb:D6VZU0|ensemblfungi:YMR117C	psi-mi:cenpt_yeast(display_long)|uniprotkb:CNN1(gene name)|psi-mi:CNN1(display_short)|uniprotkb:Co-purified with NNF1 protein 1(gene name synonym)|uniprotkb:CENP-T homolog(gene name synonym)|uniprotkb:Constitutive centromere-associated network protein CNN1(gene name synonym)|uniprotkb:YFR046C(locus name)	psi-mi:spc24_yeast(display_long)|uniprotkb:SPC24(gene name)|psi-mi:SPC24(display_short)|uniprotkb:YM9718.16C(orf name)|uniprotkb:YMR117C(locus name)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Malvezzi et al. (2013)	pubmed:23334295|imex:IM-22196	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9076769|imex:IM-22196-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001942|refseq:NP_116704.1|dip:DIP-5186N|ensemblfungi:YFR046C(gene)|ensemblfungi:YFR046C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:1901720"(negative regulation of NMS complex assembly)|rcsb pdb:4GEQ|rcsb pdb:6WUC|rcsb pdb:6YPC	refseq:NP_013835.1|sgd:S000004723|mint:Q04477|dip:DIP-893N|ensemblfungi:YMR117C(gene)|ensemblfungi:YMR117C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF	-	crc64:48CEEC087A056D42	crc64:8BE4B8619DD4C8FB	figure legend:f5c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:16.0x10^-9(molar)	2014/01/07	2014/10/16	rogid:Pkvt7uOWT2WqZlcWh8NeZH67Mvs559292	rogid:B12w0JvNs2He1WjK6c241nF3pZc559292	intact-crc:9EEE6E7C42757110|rigid:/GG1YCjvGaMSXVZOMBYLsFt20Gk	false	binding-associated region:1-270	binding-associated region:155-213	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43618	uniprotkb:P40014	intact:EBI-23036|uniprotkb:D6VTS9|uniprotkb:Q6B2K8|ensemblfungi:YFR046C	intact:EBI-22458|uniprotkb:D3DLR6|ensemblfungi:YER018C	psi-mi:cenpt_yeast(display_long)|uniprotkb:CNN1(gene name)|psi-mi:CNN1(display_short)|uniprotkb:Co-purified with NNF1 protein 1(gene name synonym)|uniprotkb:CENP-T homolog(gene name synonym)|uniprotkb:Constitutive centromere-associated network protein CNN1(gene name synonym)|uniprotkb:YFR046C(locus name)	psi-mi:spc25_yeast(display_long)|uniprotkb:YER018C(locus name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Malvezzi et al. (2013)	pubmed:23334295|imex:IM-22196	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9076769|imex:IM-22196-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001942|refseq:NP_116704.1|dip:DIP-5186N|ensemblfungi:YFR046C(gene)|ensemblfungi:YFR046C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:1901720"(negative regulation of NMS complex assembly)|rcsb pdb:4GEQ|rcsb pdb:6WUC|rcsb pdb:6YPC	refseq:NP_010934.3|sgd:S000000820|dip:DIP-2990N|mint:P40014|ensemblfungi:YER018C(gene)|ensemblfungi:YER018C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF	-	crc64:48CEEC087A056D42	crc64:1BED6CCFF330A5D8	figure legend:f5c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:16.0x10^-9(molar)	2014/01/07	2014/10/16	rogid:Pkvt7uOWT2WqZlcWh8NeZH67Mvs559292	rogid:i5gKRZA7GAjnCVzuX/qP8YmpQRA559292	intact-crc:9EEE6E7C42757110|rigid:/GG1YCjvGaMSXVZOMBYLsFt20Gk	false	binding-associated region:1-270	binding-associated region:133-221	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43618	uniprotkb:Q04477	intact:EBI-23036|uniprotkb:D6VTS9|uniprotkb:Q6B2K8|ensemblfungi:YFR046C	intact:EBI-27228|uniprotkb:D6VZU0|ensemblfungi:YMR117C	psi-mi:cenpt_yeast(display_long)|uniprotkb:CNN1(gene name)|psi-mi:CNN1(display_short)|uniprotkb:Co-purified with NNF1 protein 1(gene name synonym)|uniprotkb:CENP-T homolog(gene name synonym)|uniprotkb:Constitutive centromere-associated network protein CNN1(gene name synonym)|uniprotkb:YFR046C(locus name)	psi-mi:spc24_yeast(display_long)|uniprotkb:SPC24(gene name)|psi-mi:SPC24(display_short)|uniprotkb:YM9718.16C(orf name)|uniprotkb:YMR117C(locus name)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Malvezzi et al. (2013)	pubmed:23334295|imex:IM-22196	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9076737|imex:IM-22196-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001942|refseq:NP_116704.1|dip:DIP-5186N|ensemblfungi:YFR046C(gene)|ensemblfungi:YFR046C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:1901720"(negative regulation of NMS complex assembly)|rcsb pdb:4GEQ|rcsb pdb:6WUC|rcsb pdb:6YPC	refseq:NP_013835.1|sgd:S000004723|mint:Q04477|dip:DIP-893N|ensemblfungi:YMR117C(gene)|ensemblfungi:YMR117C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF	-	crc64:48CEEC087A056D42	crc64:8BE4B8619DD4C8FB	figure legend:sf3b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:3.5x10^-6(molar)	2014/01/07	2014/10/16	rogid:Pkvt7uOWT2WqZlcWh8NeZH67Mvs559292	rogid:B12w0JvNs2He1WjK6c241nF3pZc559292	intact-crc:3D602AE866847498|rigid:/GG1YCjvGaMSXVZOMBYLsFt20Gk	false	binding-associated region:60-84|mutation disrupting interaction:70-70	binding-associated region:155-213	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43618	uniprotkb:P40014	intact:EBI-23036|uniprotkb:D6VTS9|uniprotkb:Q6B2K8|ensemblfungi:YFR046C	intact:EBI-22458|uniprotkb:D3DLR6|ensemblfungi:YER018C	psi-mi:cenpt_yeast(display_long)|uniprotkb:CNN1(gene name)|psi-mi:CNN1(display_short)|uniprotkb:Co-purified with NNF1 protein 1(gene name synonym)|uniprotkb:CENP-T homolog(gene name synonym)|uniprotkb:Constitutive centromere-associated network protein CNN1(gene name synonym)|uniprotkb:YFR046C(locus name)	psi-mi:spc25_yeast(display_long)|uniprotkb:YER018C(locus name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Malvezzi et al. (2013)	pubmed:23334295|imex:IM-22196	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9076737|imex:IM-22196-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001942|refseq:NP_116704.1|dip:DIP-5186N|ensemblfungi:YFR046C(gene)|ensemblfungi:YFR046C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:1901720"(negative regulation of NMS complex assembly)|rcsb pdb:4GEQ|rcsb pdb:6WUC|rcsb pdb:6YPC	refseq:NP_010934.3|sgd:S000000820|dip:DIP-2990N|mint:P40014|ensemblfungi:YER018C(gene)|ensemblfungi:YER018C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF	-	crc64:48CEEC087A056D42	crc64:1BED6CCFF330A5D8	figure legend:sf3b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:3.5x10^-6(molar)	2014/01/07	2014/10/16	rogid:Pkvt7uOWT2WqZlcWh8NeZH67Mvs559292	rogid:i5gKRZA7GAjnCVzuX/qP8YmpQRA559292	intact-crc:3D602AE866847498|rigid:/GG1YCjvGaMSXVZOMBYLsFt20Gk	false	binding-associated region:60-84|mutation disrupting interaction:70-70	binding-associated region:133-221	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43618	uniprotkb:Q04477	intact:EBI-23036|uniprotkb:D6VTS9|uniprotkb:Q6B2K8|ensemblfungi:YFR046C	intact:EBI-27228|uniprotkb:D6VZU0|ensemblfungi:YMR117C	psi-mi:cenpt_yeast(display_long)|uniprotkb:CNN1(gene name)|psi-mi:CNN1(display_short)|uniprotkb:Co-purified with NNF1 protein 1(gene name synonym)|uniprotkb:CENP-T homolog(gene name synonym)|uniprotkb:Constitutive centromere-associated network protein CNN1(gene name synonym)|uniprotkb:YFR046C(locus name)	psi-mi:spc24_yeast(display_long)|uniprotkb:SPC24(gene name)|psi-mi:SPC24(display_short)|uniprotkb:YM9718.16C(orf name)|uniprotkb:YMR117C(locus name)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Malvezzi et al. (2013)	pubmed:23334295|imex:IM-22196	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9076685|imex:IM-22196-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001942|refseq:NP_116704.1|dip:DIP-5186N|ensemblfungi:YFR046C(gene)|ensemblfungi:YFR046C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:1901720"(negative regulation of NMS complex assembly)|rcsb pdb:4GEQ|rcsb pdb:6WUC|rcsb pdb:6YPC	refseq:NP_013835.1|sgd:S000004723|mint:Q04477|dip:DIP-893N|ensemblfungi:YMR117C(gene)|ensemblfungi:YMR117C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF	-	crc64:48CEEC087A056D42	crc64:8BE4B8619DD4C8FB	figure legend:sf3b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:3.5x10^-6(molar)	2014/01/07	2014/10/16	rogid:Pkvt7uOWT2WqZlcWh8NeZH67Mvs559292	rogid:B12w0JvNs2He1WjK6c241nF3pZc559292	intact-crc:C5F2997C8C47DB10|rigid:/GG1YCjvGaMSXVZOMBYLsFt20Gk	false	binding-associated region:60-84|mutation disrupting interaction:70-70,69-69,73-73	binding-associated region:155-213	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43618	uniprotkb:P40014	intact:EBI-23036|uniprotkb:D6VTS9|uniprotkb:Q6B2K8|ensemblfungi:YFR046C	intact:EBI-22458|uniprotkb:D3DLR6|ensemblfungi:YER018C	psi-mi:cenpt_yeast(display_long)|uniprotkb:CNN1(gene name)|psi-mi:CNN1(display_short)|uniprotkb:Co-purified with NNF1 protein 1(gene name synonym)|uniprotkb:CENP-T homolog(gene name synonym)|uniprotkb:Constitutive centromere-associated network protein CNN1(gene name synonym)|uniprotkb:YFR046C(locus name)	psi-mi:spc25_yeast(display_long)|uniprotkb:YER018C(locus name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Malvezzi et al. (2013)	pubmed:23334295|imex:IM-22196	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9076685|imex:IM-22196-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001942|refseq:NP_116704.1|dip:DIP-5186N|ensemblfungi:YFR046C(gene)|ensemblfungi:YFR046C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:1901720"(negative regulation of NMS complex assembly)|rcsb pdb:4GEQ|rcsb pdb:6WUC|rcsb pdb:6YPC	refseq:NP_010934.3|sgd:S000000820|dip:DIP-2990N|mint:P40014|ensemblfungi:YER018C(gene)|ensemblfungi:YER018C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF	-	crc64:48CEEC087A056D42	crc64:1BED6CCFF330A5D8	figure legend:sf3b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:3.5x10^-6(molar)	2014/01/07	2014/10/16	rogid:Pkvt7uOWT2WqZlcWh8NeZH67Mvs559292	rogid:i5gKRZA7GAjnCVzuX/qP8YmpQRA559292	intact-crc:C5F2997C8C47DB10|rigid:/GG1YCjvGaMSXVZOMBYLsFt20Gk	false	binding-associated region:60-84|mutation disrupting interaction:70-70,69-69,73-73	binding-associated region:133-221	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43618	uniprotkb:Q04477	intact:EBI-23036|uniprotkb:D6VTS9|uniprotkb:Q6B2K8|ensemblfungi:YFR046C	intact:EBI-27228|uniprotkb:D6VZU0|ensemblfungi:YMR117C	psi-mi:cenpt_yeast(display_long)|uniprotkb:CNN1(gene name)|psi-mi:CNN1(display_short)|uniprotkb:Co-purified with NNF1 protein 1(gene name synonym)|uniprotkb:CENP-T homolog(gene name synonym)|uniprotkb:Constitutive centromere-associated network protein CNN1(gene name synonym)|uniprotkb:YFR046C(locus name)	psi-mi:spc24_yeast(display_long)|uniprotkb:SPC24(gene name)|psi-mi:SPC24(display_short)|uniprotkb:YM9718.16C(orf name)|uniprotkb:YMR117C(locus name)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Malvezzi et al. (2013)	pubmed:23334295|imex:IM-22196	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9076753|imex:IM-22196-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001942|refseq:NP_116704.1|dip:DIP-5186N|ensemblfungi:YFR046C(gene)|ensemblfungi:YFR046C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:1901720"(negative regulation of NMS complex assembly)|rcsb pdb:4GEQ|rcsb pdb:6WUC|rcsb pdb:6YPC	refseq:NP_013835.1|sgd:S000004723|mint:Q04477|dip:DIP-893N|ensemblfungi:YMR117C(gene)|ensemblfungi:YMR117C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF	-	crc64:48CEEC087A056D42	crc64:8BE4B8619DD4C8FB	figure legend:sf3b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:3.5x10^-6(molar)	2014/01/07	2014/10/16	rogid:Pkvt7uOWT2WqZlcWh8NeZH67Mvs559292	rogid:B12w0JvNs2He1WjK6c241nF3pZc559292	intact-crc:3ED25F08B29AE318|rigid:/GG1YCjvGaMSXVZOMBYLsFt20Gk	false	mutation disrupting interaction:73-73|binding-associated region:60-84	binding-associated region:155-213	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43618	uniprotkb:P40014	intact:EBI-23036|uniprotkb:D6VTS9|uniprotkb:Q6B2K8|ensemblfungi:YFR046C	intact:EBI-22458|uniprotkb:D3DLR6|ensemblfungi:YER018C	psi-mi:cenpt_yeast(display_long)|uniprotkb:CNN1(gene name)|psi-mi:CNN1(display_short)|uniprotkb:Co-purified with NNF1 protein 1(gene name synonym)|uniprotkb:CENP-T homolog(gene name synonym)|uniprotkb:Constitutive centromere-associated network protein CNN1(gene name synonym)|uniprotkb:YFR046C(locus name)	psi-mi:spc25_yeast(display_long)|uniprotkb:YER018C(locus name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Malvezzi et al. (2013)	pubmed:23334295|imex:IM-22196	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9076753|imex:IM-22196-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001942|refseq:NP_116704.1|dip:DIP-5186N|ensemblfungi:YFR046C(gene)|ensemblfungi:YFR046C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:1901720"(negative regulation of NMS complex assembly)|rcsb pdb:4GEQ|rcsb pdb:6WUC|rcsb pdb:6YPC	refseq:NP_010934.3|sgd:S000000820|dip:DIP-2990N|mint:P40014|ensemblfungi:YER018C(gene)|ensemblfungi:YER018C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF	-	crc64:48CEEC087A056D42	crc64:1BED6CCFF330A5D8	figure legend:sf3b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:3.5x10^-6(molar)	2014/01/07	2014/10/16	rogid:Pkvt7uOWT2WqZlcWh8NeZH67Mvs559292	rogid:i5gKRZA7GAjnCVzuX/qP8YmpQRA559292	intact-crc:3ED25F08B29AE318|rigid:/GG1YCjvGaMSXVZOMBYLsFt20Gk	false	mutation disrupting interaction:73-73|binding-associated region:60-84	binding-associated region:133-221	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43618	uniprotkb:Q04477	intact:EBI-23036|uniprotkb:D6VTS9|uniprotkb:Q6B2K8|ensemblfungi:YFR046C	intact:EBI-27228|uniprotkb:D6VZU0|ensemblfungi:YMR117C	psi-mi:cenpt_yeast(display_long)|uniprotkb:CNN1(gene name)|psi-mi:CNN1(display_short)|uniprotkb:Co-purified with NNF1 protein 1(gene name synonym)|uniprotkb:CENP-T homolog(gene name synonym)|uniprotkb:Constitutive centromere-associated network protein CNN1(gene name synonym)|uniprotkb:YFR046C(locus name)	psi-mi:spc24_yeast(display_long)|uniprotkb:SPC24(gene name)|psi-mi:SPC24(display_short)|uniprotkb:YM9718.16C(orf name)|uniprotkb:YMR117C(locus name)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Malvezzi et al. (2013)	pubmed:23334295|imex:IM-22196	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9076796|imex:IM-22196-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001942|refseq:NP_116704.1|dip:DIP-5186N|ensemblfungi:YFR046C(gene)|ensemblfungi:YFR046C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:1901720"(negative regulation of NMS complex assembly)|rcsb pdb:4GEQ|rcsb pdb:6WUC|rcsb pdb:6YPC	refseq:NP_013835.1|sgd:S000004723|mint:Q04477|dip:DIP-893N|ensemblfungi:YMR117C(gene)|ensemblfungi:YMR117C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF	-	crc64:48CEEC087A056D42	crc64:8BE4B8619DD4C8FB	figure legend:f5c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:25.0x10^-9(molar)	2014/01/07	2014/10/16	rogid:Pkvt7uOWT2WqZlcWh8NeZH67Mvs559292	rogid:B12w0JvNs2He1WjK6c241nF3pZc559292	intact-crc:2C2980F938C487C1|rigid:/GG1YCjvGaMSXVZOMBYLsFt20Gk	false	binding-associated region:1-129,167-270	binding-associated region:155-213	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43618	uniprotkb:P40014	intact:EBI-23036|uniprotkb:D6VTS9|uniprotkb:Q6B2K8|ensemblfungi:YFR046C	intact:EBI-22458|uniprotkb:D3DLR6|ensemblfungi:YER018C	psi-mi:cenpt_yeast(display_long)|uniprotkb:CNN1(gene name)|psi-mi:CNN1(display_short)|uniprotkb:Co-purified with NNF1 protein 1(gene name synonym)|uniprotkb:CENP-T homolog(gene name synonym)|uniprotkb:Constitutive centromere-associated network protein CNN1(gene name synonym)|uniprotkb:YFR046C(locus name)	psi-mi:spc25_yeast(display_long)|uniprotkb:YER018C(locus name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Malvezzi et al. (2013)	pubmed:23334295|imex:IM-22196	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9076796|imex:IM-22196-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001942|refseq:NP_116704.1|dip:DIP-5186N|ensemblfungi:YFR046C(gene)|ensemblfungi:YFR046C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:1901720"(negative regulation of NMS complex assembly)|rcsb pdb:4GEQ|rcsb pdb:6WUC|rcsb pdb:6YPC	refseq:NP_010934.3|sgd:S000000820|dip:DIP-2990N|mint:P40014|ensemblfungi:YER018C(gene)|ensemblfungi:YER018C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF	-	crc64:48CEEC087A056D42	crc64:1BED6CCFF330A5D8	figure legend:f5c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:25.0x10^-9(molar)	2014/01/07	2014/10/16	rogid:Pkvt7uOWT2WqZlcWh8NeZH67Mvs559292	rogid:i5gKRZA7GAjnCVzuX/qP8YmpQRA559292	intact-crc:2C2980F938C487C1|rigid:/GG1YCjvGaMSXVZOMBYLsFt20Gk	false	binding-associated region:1-129,167-270	binding-associated region:133-221	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43618	uniprotkb:Q04477	intact:EBI-23036|uniprotkb:D6VTS9|uniprotkb:Q6B2K8|ensemblfungi:YFR046C	intact:EBI-27228|uniprotkb:D6VZU0|ensemblfungi:YMR117C	psi-mi:cenpt_yeast(display_long)|uniprotkb:CNN1(gene name)|psi-mi:CNN1(display_short)|uniprotkb:Co-purified with NNF1 protein 1(gene name synonym)|uniprotkb:CENP-T homolog(gene name synonym)|uniprotkb:Constitutive centromere-associated network protein CNN1(gene name synonym)|uniprotkb:YFR046C(locus name)	psi-mi:spc24_yeast(display_long)|uniprotkb:SPC24(gene name)|psi-mi:SPC24(display_short)|uniprotkb:YM9718.16C(orf name)|uniprotkb:YMR117C(locus name)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Malvezzi et al. (2013)	pubmed:23334295|imex:IM-22196	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9076721|imex:IM-22196-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001942|refseq:NP_116704.1|dip:DIP-5186N|ensemblfungi:YFR046C(gene)|ensemblfungi:YFR046C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:1901720"(negative regulation of NMS complex assembly)|rcsb pdb:4GEQ|rcsb pdb:6WUC|rcsb pdb:6YPC	refseq:NP_013835.1|sgd:S000004723|mint:Q04477|dip:DIP-893N|ensemblfungi:YMR117C(gene)|ensemblfungi:YMR117C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF	-	crc64:48CEEC087A056D42	crc64:8BE4B8619DD4C8FB	figure legend:sf3b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:3.5x10^-6(molar)	2014/01/07	2014/10/16	rogid:Pkvt7uOWT2WqZlcWh8NeZH67Mvs559292	rogid:B12w0JvNs2He1WjK6c241nF3pZc559292	intact-crc:E0988842B669DD20|rigid:/GG1YCjvGaMSXVZOMBYLsFt20Gk	false	mutation disrupting interaction:69-69|binding-associated region:60-84	binding-associated region:155-213	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43618	uniprotkb:P40014	intact:EBI-23036|uniprotkb:D6VTS9|uniprotkb:Q6B2K8|ensemblfungi:YFR046C	intact:EBI-22458|uniprotkb:D3DLR6|ensemblfungi:YER018C	psi-mi:cenpt_yeast(display_long)|uniprotkb:CNN1(gene name)|psi-mi:CNN1(display_short)|uniprotkb:Co-purified with NNF1 protein 1(gene name synonym)|uniprotkb:CENP-T homolog(gene name synonym)|uniprotkb:Constitutive centromere-associated network protein CNN1(gene name synonym)|uniprotkb:YFR046C(locus name)	psi-mi:spc25_yeast(display_long)|uniprotkb:YER018C(locus name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Malvezzi et al. (2013)	pubmed:23334295|imex:IM-22196	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9076721|imex:IM-22196-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001942|refseq:NP_116704.1|dip:DIP-5186N|ensemblfungi:YFR046C(gene)|ensemblfungi:YFR046C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:1901720"(negative regulation of NMS complex assembly)|rcsb pdb:4GEQ|rcsb pdb:6WUC|rcsb pdb:6YPC	refseq:NP_010934.3|sgd:S000000820|dip:DIP-2990N|mint:P40014|ensemblfungi:YER018C(gene)|ensemblfungi:YER018C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF	-	crc64:48CEEC087A056D42	crc64:1BED6CCFF330A5D8	figure legend:sf3b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:3.5x10^-6(molar)	2014/01/07	2014/10/16	rogid:Pkvt7uOWT2WqZlcWh8NeZH67Mvs559292	rogid:i5gKRZA7GAjnCVzuX/qP8YmpQRA559292	intact-crc:E0988842B669DD20|rigid:/GG1YCjvGaMSXVZOMBYLsFt20Gk	false	mutation disrupting interaction:69-69|binding-associated region:60-84	binding-associated region:133-221	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43618	uniprotkb:Q04477	intact:EBI-23036|uniprotkb:D6VTS9|uniprotkb:Q6B2K8|ensemblfungi:YFR046C	intact:EBI-27228|uniprotkb:D6VZU0|ensemblfungi:YMR117C	psi-mi:cenpt_yeast(display_long)|uniprotkb:CNN1(gene name)|psi-mi:CNN1(display_short)|uniprotkb:Co-purified with NNF1 protein 1(gene name synonym)|uniprotkb:CENP-T homolog(gene name synonym)|uniprotkb:Constitutive centromere-associated network protein CNN1(gene name synonym)|uniprotkb:YFR046C(locus name)	psi-mi:spc24_yeast(display_long)|uniprotkb:SPC24(gene name)|psi-mi:SPC24(display_short)|uniprotkb:YM9718.16C(orf name)|uniprotkb:YMR117C(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Malvezzi et al. (2013)	pubmed:23334295|imex:IM-22196	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9076143|imex:IM-22196-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001942|refseq:NP_116704.1|dip:DIP-5186N|ensemblfungi:YFR046C(gene)|ensemblfungi:YFR046C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:1901720"(negative regulation of NMS complex assembly)|rcsb pdb:4GEQ|rcsb pdb:6WUC|rcsb pdb:6YPC	refseq:NP_013835.1|sgd:S000004723|mint:Q04477|dip:DIP-893N|ensemblfungi:YMR117C(gene)|ensemblfungi:YMR117C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF	rcsb pdb:4GEQ	crc64:48CEEC087A056D42	crc64:8BE4B8619DD4C8FB	figure legend:f1c f1d f2a t1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/01/07	2014/10/16	rogid:Pkvt7uOWT2WqZlcWh8NeZH67Mvs559292	rogid:B12w0JvNs2He1WjK6c241nF3pZc559292	intact-crc:A803E17F4BEF82DE|rigid:/GG1YCjvGaMSXVZOMBYLsFt20Gk	false	binding-associated region:60-84	binding-associated region:155-213	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43618	uniprotkb:P40014	intact:EBI-23036|uniprotkb:D6VTS9|uniprotkb:Q6B2K8|ensemblfungi:YFR046C	intact:EBI-22458|uniprotkb:D3DLR6|ensemblfungi:YER018C	psi-mi:cenpt_yeast(display_long)|uniprotkb:CNN1(gene name)|psi-mi:CNN1(display_short)|uniprotkb:Co-purified with NNF1 protein 1(gene name synonym)|uniprotkb:CENP-T homolog(gene name synonym)|uniprotkb:Constitutive centromere-associated network protein CNN1(gene name synonym)|uniprotkb:YFR046C(locus name)	psi-mi:spc25_yeast(display_long)|uniprotkb:YER018C(locus name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short)	psi-mi:"MI:0114"(x-ray crystallography)	Malvezzi et al. (2013)	pubmed:23334295|imex:IM-22196	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9076143|imex:IM-22196-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001942|refseq:NP_116704.1|dip:DIP-5186N|ensemblfungi:YFR046C(gene)|ensemblfungi:YFR046C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:1901720"(negative regulation of NMS complex assembly)|rcsb pdb:4GEQ|rcsb pdb:6WUC|rcsb pdb:6YPC	refseq:NP_010934.3|sgd:S000000820|dip:DIP-2990N|mint:P40014|ensemblfungi:YER018C(gene)|ensemblfungi:YER018C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF	rcsb pdb:4GEQ	crc64:48CEEC087A056D42	crc64:1BED6CCFF330A5D8	figure legend:f1c f1d f2a t1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/01/07	2014/10/16	rogid:Pkvt7uOWT2WqZlcWh8NeZH67Mvs559292	rogid:i5gKRZA7GAjnCVzuX/qP8YmpQRA559292	intact-crc:A803E17F4BEF82DE|rigid:/GG1YCjvGaMSXVZOMBYLsFt20Gk	false	binding-associated region:60-84	binding-associated region:133-221	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43618	uniprotkb:Q04477	intact:EBI-23036|uniprotkb:D6VTS9|uniprotkb:Q6B2K8|ensemblfungi:YFR046C	intact:EBI-27228|uniprotkb:D6VZU0|ensemblfungi:YMR117C	psi-mi:cenpt_yeast(display_long)|uniprotkb:CNN1(gene name)|psi-mi:CNN1(display_short)|uniprotkb:Co-purified with NNF1 protein 1(gene name synonym)|uniprotkb:CENP-T homolog(gene name synonym)|uniprotkb:Constitutive centromere-associated network protein CNN1(gene name synonym)|uniprotkb:YFR046C(locus name)	psi-mi:spc24_yeast(display_long)|uniprotkb:SPC24(gene name)|psi-mi:SPC24(display_short)|uniprotkb:YM9718.16C(orf name)|uniprotkb:YMR117C(locus name)	psi-mi:"MI:0071"(molecular sieving)	Malvezzi et al. (2013)	pubmed:23334295|imex:IM-22196	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9076483|imex:IM-22196-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001942|refseq:NP_116704.1|dip:DIP-5186N|ensemblfungi:YFR046C(gene)|ensemblfungi:YFR046C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:1901720"(negative regulation of NMS complex assembly)|rcsb pdb:4GEQ|rcsb pdb:6WUC|rcsb pdb:6YPC	refseq:NP_013835.1|sgd:S000004723|mint:Q04477|dip:DIP-893N|ensemblfungi:YMR117C(gene)|ensemblfungi:YMR117C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF	-	crc64:48CEEC087A056D42	crc64:8BE4B8619DD4C8FB	figure legend:f3d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/01/07	2014/10/16	rogid:Pkvt7uOWT2WqZlcWh8NeZH67Mvs559292	rogid:B12w0JvNs2He1WjK6c241nF3pZc559292	intact-crc:8A8C373C056DDA65|rigid:/GG1YCjvGaMSXVZOMBYLsFt20Gk	false	his tag:?-?|binding-associated region:1-270	his tag:?-?|binding-associated region:155-213	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P43618	uniprotkb:P40014	intact:EBI-23036|uniprotkb:D6VTS9|uniprotkb:Q6B2K8|ensemblfungi:YFR046C	intact:EBI-22458|uniprotkb:D3DLR6|ensemblfungi:YER018C	psi-mi:cenpt_yeast(display_long)|uniprotkb:CNN1(gene name)|psi-mi:CNN1(display_short)|uniprotkb:Co-purified with NNF1 protein 1(gene name synonym)|uniprotkb:CENP-T homolog(gene name synonym)|uniprotkb:Constitutive centromere-associated network protein CNN1(gene name synonym)|uniprotkb:YFR046C(locus name)	psi-mi:spc25_yeast(display_long)|uniprotkb:YER018C(locus name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short)	psi-mi:"MI:0071"(molecular sieving)	Malvezzi et al. (2013)	pubmed:23334295|imex:IM-22196	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9076483|imex:IM-22196-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001942|refseq:NP_116704.1|dip:DIP-5186N|ensemblfungi:YFR046C(gene)|ensemblfungi:YFR046C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:1901720"(negative regulation of NMS complex assembly)|rcsb pdb:4GEQ|rcsb pdb:6WUC|rcsb pdb:6YPC	refseq:NP_010934.3|sgd:S000000820|dip:DIP-2990N|mint:P40014|ensemblfungi:YER018C(gene)|ensemblfungi:YER018C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF	-	crc64:48CEEC087A056D42	crc64:1BED6CCFF330A5D8	figure legend:f3d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/01/07	2014/10/16	rogid:Pkvt7uOWT2WqZlcWh8NeZH67Mvs559292	rogid:i5gKRZA7GAjnCVzuX/qP8YmpQRA559292	intact-crc:8A8C373C056DDA65|rigid:/GG1YCjvGaMSXVZOMBYLsFt20Gk	false	his tag:?-?|binding-associated region:1-270	mutation disrupting interaction:159-159|binding-associated region:133-221	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P43618	uniprotkb:Q04477	intact:EBI-23036|uniprotkb:D6VTS9|uniprotkb:Q6B2K8|ensemblfungi:YFR046C	intact:EBI-27228|uniprotkb:D6VZU0|ensemblfungi:YMR117C	psi-mi:cenpt_yeast(display_long)|uniprotkb:CNN1(gene name)|psi-mi:CNN1(display_short)|uniprotkb:Co-purified with NNF1 protein 1(gene name synonym)|uniprotkb:CENP-T homolog(gene name synonym)|uniprotkb:Constitutive centromere-associated network protein CNN1(gene name synonym)|uniprotkb:YFR046C(locus name)	psi-mi:spc24_yeast(display_long)|uniprotkb:SPC24(gene name)|psi-mi:SPC24(display_short)|uniprotkb:YM9718.16C(orf name)|uniprotkb:YMR117C(locus name)	psi-mi:"MI:0071"(molecular sieving)	Malvezzi et al. (2013)	pubmed:23334295|imex:IM-22196	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9077006|imex:IM-22196-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001942|refseq:NP_116704.1|dip:DIP-5186N|ensemblfungi:YFR046C(gene)|ensemblfungi:YFR046C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:1901720"(negative regulation of NMS complex assembly)|rcsb pdb:4GEQ|rcsb pdb:6WUC|rcsb pdb:6YPC	refseq:NP_013835.1|sgd:S000004723|mint:Q04477|dip:DIP-893N|ensemblfungi:YMR117C(gene)|ensemblfungi:YMR117C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF	-	crc64:48CEEC087A056D42	crc64:8BE4B8619DD4C8FB	figure legend:f6g|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/01/07	2014/10/16	rogid:Pkvt7uOWT2WqZlcWh8NeZH67Mvs559292	rogid:B12w0JvNs2He1WjK6c241nF3pZc559292	intact-crc:F1A15BC1822EF686|rigid:/GG1YCjvGaMSXVZOMBYLsFt20Gk	false	binding-associated region:1-270|his tag:?-?|mutation disrupting interaction:74-74	his tag:?-?	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P43618	uniprotkb:P40014	intact:EBI-23036|uniprotkb:D6VTS9|uniprotkb:Q6B2K8|ensemblfungi:YFR046C	intact:EBI-22458|uniprotkb:D3DLR6|ensemblfungi:YER018C	psi-mi:cenpt_yeast(display_long)|uniprotkb:CNN1(gene name)|psi-mi:CNN1(display_short)|uniprotkb:Co-purified with NNF1 protein 1(gene name synonym)|uniprotkb:CENP-T homolog(gene name synonym)|uniprotkb:Constitutive centromere-associated network protein CNN1(gene name synonym)|uniprotkb:YFR046C(locus name)	psi-mi:spc25_yeast(display_long)|uniprotkb:YER018C(locus name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short)	psi-mi:"MI:0071"(molecular sieving)	Malvezzi et al. (2013)	pubmed:23334295|imex:IM-22196	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9077006|imex:IM-22196-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001942|refseq:NP_116704.1|dip:DIP-5186N|ensemblfungi:YFR046C(gene)|ensemblfungi:YFR046C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:1901720"(negative regulation of NMS complex assembly)|rcsb pdb:4GEQ|rcsb pdb:6WUC|rcsb pdb:6YPC	refseq:NP_010934.3|sgd:S000000820|dip:DIP-2990N|mint:P40014|ensemblfungi:YER018C(gene)|ensemblfungi:YER018C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF	-	crc64:48CEEC087A056D42	crc64:1BED6CCFF330A5D8	figure legend:f6g|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/01/07	2014/10/16	rogid:Pkvt7uOWT2WqZlcWh8NeZH67Mvs559292	rogid:i5gKRZA7GAjnCVzuX/qP8YmpQRA559292	intact-crc:F1A15BC1822EF686|rigid:/GG1YCjvGaMSXVZOMBYLsFt20Gk	false	binding-associated region:1-270|his tag:?-?|mutation disrupting interaction:74-74	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P40568	uniprotkb:P39731	intact:EBI-25398|uniprotkb:D6VVU0|ensemblfungi:YIR010W	intact:EBI-11606|uniprotkb:D6VPI3|ensemblfungi:YAL034W-A	psi-mi:dsn1_yeast(display_long)|uniprotkb:YIB10W(orf name)|uniprotkb:YIR010W(locus name)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)	psi-mi:mtw1_yeast(display_long)|uniprotkb:MTW1(gene name)|psi-mi:MTW1(display_short)|uniprotkb:YAL034W-A(locus name)|uniprotkb:YAL034AW(orf name)|uniprotkb:DSN3(gene name synonym)|uniprotkb:NSL2(gene name synonym)|uniprotkb:Mis12-like protein(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Malvezzi et al. (2013)	pubmed:23334295|imex:IM-22196	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9076905|imex:IM-22196-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001449|refseq:NP_012275.3|mint:P40568|dip:DIP-4794N|ensemblfungi:YIR010W(gene)|ensemblfungi:YIR010W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000922"(spindle pole)|go:"GO:0000939"(inner kinetochore)|go:"GO:0007059"(chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|interpro:IPR018247|rcsb pdb:5T6J|rcsb pdb:6MJE|reactome:R-SCE-6798695	ensemblfungi:YAL034W-A(gene)|ensemblfungi:YAL034W-A_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR008685(Mis12)|refseq:NP_009367.1|sgd:S000000032|mint:P39731|dip:DIP-1464N	-	-	-	figure legend:f4d|comment:"Strikingly, the deletion of the 29 terminal residues of  Dsn1, although not compromising Mtw1 complex assembly,  completely disrupted the binding to the Ndc80 complex  (Figure 4D)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/01/07	2014/10/16	rogid:DfxCEgsBR5iDmrfMZEzeaxrZyls559292	rogid:p+tSpERopX07gzW0YKWtjDQg+Tk559292	intact-crc:FFAA39EEECED99BF|rigid:x5aDq63JfkDYhlniYYUV2staR18	false	binding-associated region:172-547|his tag:?-?	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P40568	uniprotkb:P40460	intact:EBI-25398|uniprotkb:D6VVU0|ensemblfungi:YIR010W	intact:EBI-25247|uniprotkb:D6VVE3|ensemblfungi:YIL144W	psi-mi:dsn1_yeast(display_long)|uniprotkb:YIB10W(orf name)|uniprotkb:YIR010W(locus name)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)	psi-mi:ndc80_yeast(display_long)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:80 kDa spindle component protein(gene name synonym)|uniprotkb:HEC1(gene name synonym)|uniprotkb:Nuclear division cycle protein 80(gene name synonym)|uniprotkb:TID3(gene name synonym)|uniprotkb:Two-hybrid interaction with DMC1 protein 3(gene name synonym)|uniprotkb:YIL144W(locus name)	psi-mi:"MI:0071"(molecular sieving)	Malvezzi et al. (2013)	pubmed:23334295|imex:IM-22196	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9076905|imex:IM-22196-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001449|refseq:NP_012275.3|mint:P40568|dip:DIP-4794N|ensemblfungi:YIR010W(gene)|ensemblfungi:YIR010W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000922"(spindle pole)|go:"GO:0000939"(inner kinetochore)|go:"GO:0007059"(chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|interpro:IPR018247|rcsb pdb:5T6J|rcsb pdb:6MJE|reactome:R-SCE-6798695	sgd:S000001406|refseq:NP_012122.3|mint:P40460|dip:DIP-818N|ensemblfungi:YIL144W(gene)|ensemblfungi:YIL144W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF	-	-	crc64:7DBC492227A80093	figure legend:f4d|comment:"Strikingly, the deletion of the 29 terminal residues of  Dsn1, although not compromising Mtw1 complex assembly,  completely disrupted the binding to the Ndc80 complex  (Figure 4D)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/01/07	2014/10/16	rogid:DfxCEgsBR5iDmrfMZEzeaxrZyls559292	rogid:ZrT7N4pBKz6upSglhGhOqgeoAYw559292	intact-crc:FFAA39EEECED99BF|rigid:x5aDq63JfkDYhlniYYUV2staR18	false	binding-associated region:172-547|his tag:?-?	his tag:?-?	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P40568	uniprotkb:P47149	intact:EBI-25398|uniprotkb:D6VVU0|ensemblfungi:YIR010W	intact:EBI-12098|uniprotkb:Q06779|uniprotkb:D6VWT1|ensemblfungi:YJR112W	psi-mi:dsn1_yeast(display_long)|uniprotkb:YIB10W(orf name)|uniprotkb:YIR010W(locus name)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)	psi-mi:nnf1_yeast(display_long)|uniprotkb:J2011(orf name)|uniprotkb:YJR112W(locus name)|uniprotkb:NNF1(gene name)|psi-mi:NNF1(display_short)	psi-mi:"MI:0071"(molecular sieving)	Malvezzi et al. (2013)	pubmed:23334295|imex:IM-22196	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9076905|imex:IM-22196-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001449|refseq:NP_012275.3|mint:P40568|dip:DIP-4794N|ensemblfungi:YIR010W(gene)|ensemblfungi:YIR010W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000922"(spindle pole)|go:"GO:0000939"(inner kinetochore)|go:"GO:0007059"(chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|interpro:IPR018247|rcsb pdb:5T6J|rcsb pdb:6MJE|reactome:R-SCE-6798695	ensemblfungi:YJR112W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0051301"(cell division)|interpro:IPR007128(Nnf1)|interpro:IPR016851(Kinetochore-associated protein Nnf1p)|ensemblfungi:YJR112W(gene)|refseq:NP_012646.3|sgd:S000003873|mint:P47149|dip:DIP-3017N	-	-	-	figure legend:f4d|comment:"Strikingly, the deletion of the 29 terminal residues of  Dsn1, although not compromising Mtw1 complex assembly,  completely disrupted the binding to the Ndc80 complex  (Figure 4D)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/01/07	2014/10/16	rogid:DfxCEgsBR5iDmrfMZEzeaxrZyls559292	rogid:fveaY324dma1QT0Cugtm+8PPV2A559292	intact-crc:FFAA39EEECED99BF|rigid:x5aDq63JfkDYhlniYYUV2staR18	false	binding-associated region:172-547|his tag:?-?	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P40568	uniprotkb:Q12143	intact:EBI-25398|uniprotkb:D6VVU0|ensemblfungi:YIR010W	intact:EBI-33666|uniprotkb:Q6B152|uniprotkb:D6W3D7|ensemblfungi:YPL233W	psi-mi:dsn1_yeast(display_long)|uniprotkb:YIB10W(orf name)|uniprotkb:YIR010W(locus name)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)	psi-mi:nsl1_yeast(display_long)|uniprotkb:NSL1(gene name)|psi-mi:NSL1(display_short)|uniprotkb:YPL233W(locus name)	psi-mi:"MI:0071"(molecular sieving)	Malvezzi et al. (2013)	pubmed:23334295|imex:IM-22196	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9076905|imex:IM-22196-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001449|refseq:NP_012275.3|mint:P40568|dip:DIP-4794N|ensemblfungi:YIR010W(gene)|ensemblfungi:YIR010W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000922"(spindle pole)|go:"GO:0000939"(inner kinetochore)|go:"GO:0007059"(chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|interpro:IPR018247|rcsb pdb:5T6J|rcsb pdb:6MJE|reactome:R-SCE-6798695	refseq:NP_015091.1|sgd:S000006154|mint:Q12143|dip:DIP-5393N|ensemblfungi:YPL233W(gene)|ensemblfungi:YPL233W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000922"(spindle pole)|go:"GO:0007059"(chromosome segregation)|go:"GO:0051301"(cell division)|interpro:IPR013950(Kinetochore Mis14)	-	-	-	figure legend:f4d|comment:"Strikingly, the deletion of the 29 terminal residues of  Dsn1, although not compromising Mtw1 complex assembly,  completely disrupted the binding to the Ndc80 complex  (Figure 4D)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/01/07	2014/10/16	rogid:DfxCEgsBR5iDmrfMZEzeaxrZyls559292	rogid:WAB+WzTulMOWWY5f5mUAmwh3z6o559292	intact-crc:FFAA39EEECED99BF|rigid:x5aDq63JfkDYhlniYYUV2staR18	false	binding-associated region:172-547|his tag:?-?	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P40568	uniprotkb:P33895	intact:EBI-25398|uniprotkb:D6VVU0|ensemblfungi:YIR010W	intact:EBI-12377|uniprotkb:Q6B1X5|ensemblfungi:YOL069W|uniprotkb:D6W1Z8	psi-mi:dsn1_yeast(display_long)|uniprotkb:YIB10W(orf name)|uniprotkb:YIR010W(locus name)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)	psi-mi:nuf2_yeast(display_long)|uniprotkb:YOL069W(locus name)|uniprotkb:NUF2(gene name)|psi-mi:NUF2(display_short)	psi-mi:"MI:0071"(molecular sieving)	Malvezzi et al. (2013)	pubmed:23334295|imex:IM-22196	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9076905|imex:IM-22196-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001449|refseq:NP_012275.3|mint:P40568|dip:DIP-4794N|ensemblfungi:YIR010W(gene)|ensemblfungi:YIR010W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000922"(spindle pole)|go:"GO:0000939"(inner kinetochore)|go:"GO:0007059"(chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|interpro:IPR018247|rcsb pdb:5T6J|rcsb pdb:6MJE|reactome:R-SCE-6798695	ensemblfungi:YOL069W(gene)|ensemblfungi:YOL069W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005816"(spindle pole body)|go:"GO:0005876"(spindle microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|interpro:IPR005549(Nuf2)|interpro:IPR038275|rcsb pdb:5TCS|rcsb pdb:5TD8|go:"GO:0045132"(meiotic chromosome segregation)|refseq:NP_014572.1|sgd:S000005430|mint:P33895|dip:DIP-1481N	-	-	-	figure legend:f4d|comment:"Strikingly, the deletion of the 29 terminal residues of  Dsn1, although not compromising Mtw1 complex assembly,  completely disrupted the binding to the Ndc80 complex  (Figure 4D)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/01/07	2014/10/16	rogid:DfxCEgsBR5iDmrfMZEzeaxrZyls559292	rogid:oof/8nhKWQCx5bp4lvc7f33OO+0559292	intact-crc:FFAA39EEECED99BF|rigid:x5aDq63JfkDYhlniYYUV2staR18	false	binding-associated region:172-547|his tag:?-?	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P40568	uniprotkb:Q04477	intact:EBI-25398|uniprotkb:D6VVU0|ensemblfungi:YIR010W	intact:EBI-27228|uniprotkb:D6VZU0|ensemblfungi:YMR117C	psi-mi:dsn1_yeast(display_long)|uniprotkb:YIB10W(orf name)|uniprotkb:YIR010W(locus name)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)	psi-mi:spc24_yeast(display_long)|uniprotkb:SPC24(gene name)|psi-mi:SPC24(display_short)|uniprotkb:YM9718.16C(orf name)|uniprotkb:YMR117C(locus name)	psi-mi:"MI:0071"(molecular sieving)	Malvezzi et al. (2013)	pubmed:23334295|imex:IM-22196	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9076905|imex:IM-22196-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001449|refseq:NP_012275.3|mint:P40568|dip:DIP-4794N|ensemblfungi:YIR010W(gene)|ensemblfungi:YIR010W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000922"(spindle pole)|go:"GO:0000939"(inner kinetochore)|go:"GO:0007059"(chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|interpro:IPR018247|rcsb pdb:5T6J|rcsb pdb:6MJE|reactome:R-SCE-6798695	refseq:NP_013835.1|sgd:S000004723|mint:Q04477|dip:DIP-893N|ensemblfungi:YMR117C(gene)|ensemblfungi:YMR117C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF	-	-	crc64:8BE4B8619DD4C8FB	figure legend:f4d|comment:"Strikingly, the deletion of the 29 terminal residues of  Dsn1, although not compromising Mtw1 complex assembly,  completely disrupted the binding to the Ndc80 complex  (Figure 4D)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/01/07	2014/10/16	rogid:DfxCEgsBR5iDmrfMZEzeaxrZyls559292	rogid:B12w0JvNs2He1WjK6c241nF3pZc559292	intact-crc:FFAA39EEECED99BF|rigid:x5aDq63JfkDYhlniYYUV2staR18	false	binding-associated region:172-547|his tag:?-?	his tag:?-?	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P40568	uniprotkb:P40014	intact:EBI-25398|uniprotkb:D6VVU0|ensemblfungi:YIR010W	intact:EBI-22458|uniprotkb:D3DLR6|ensemblfungi:YER018C	psi-mi:dsn1_yeast(display_long)|uniprotkb:YIB10W(orf name)|uniprotkb:YIR010W(locus name)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)	psi-mi:spc25_yeast(display_long)|uniprotkb:YER018C(locus name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short)	psi-mi:"MI:0071"(molecular sieving)	Malvezzi et al. (2013)	pubmed:23334295|imex:IM-22196	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9076905|imex:IM-22196-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001449|refseq:NP_012275.3|mint:P40568|dip:DIP-4794N|ensemblfungi:YIR010W(gene)|ensemblfungi:YIR010W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000922"(spindle pole)|go:"GO:0000939"(inner kinetochore)|go:"GO:0007059"(chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|interpro:IPR018247|rcsb pdb:5T6J|rcsb pdb:6MJE|reactome:R-SCE-6798695	refseq:NP_010934.3|sgd:S000000820|dip:DIP-2990N|mint:P40014|ensemblfungi:YER018C(gene)|ensemblfungi:YER018C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF	-	-	crc64:1BED6CCFF330A5D8	figure legend:f4d|comment:"Strikingly, the deletion of the 29 terminal residues of  Dsn1, although not compromising Mtw1 complex assembly,  completely disrupted the binding to the Ndc80 complex  (Figure 4D)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/01/07	2014/10/16	rogid:DfxCEgsBR5iDmrfMZEzeaxrZyls559292	rogid:i5gKRZA7GAjnCVzuX/qP8YmpQRA559292	intact-crc:FFAA39EEECED99BF|rigid:x5aDq63JfkDYhlniYYUV2staR18	false	binding-associated region:172-547|his tag:?-?	mutation disrupting interaction:159-159	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P40568	uniprotkb:P39731	intact:EBI-25398|uniprotkb:D6VVU0|ensemblfungi:YIR010W	intact:EBI-11606|uniprotkb:D6VPI3|ensemblfungi:YAL034W-A	psi-mi:dsn1_yeast(display_long)|uniprotkb:YIB10W(orf name)|uniprotkb:YIR010W(locus name)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)	psi-mi:mtw1_yeast(display_long)|uniprotkb:MTW1(gene name)|psi-mi:MTW1(display_short)|uniprotkb:YAL034W-A(locus name)|uniprotkb:YAL034AW(orf name)|uniprotkb:DSN3(gene name synonym)|uniprotkb:NSL2(gene name synonym)|uniprotkb:Mis12-like protein(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Malvezzi et al. (2013)	pubmed:23334295|imex:IM-22196	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9076935|imex:IM-22196-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001449|refseq:NP_012275.3|mint:P40568|dip:DIP-4794N|ensemblfungi:YIR010W(gene)|ensemblfungi:YIR010W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000922"(spindle pole)|go:"GO:0000939"(inner kinetochore)|go:"GO:0007059"(chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|interpro:IPR018247|rcsb pdb:5T6J|rcsb pdb:6MJE|reactome:R-SCE-6798695	ensemblfungi:YAL034W-A(gene)|ensemblfungi:YAL034W-A_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR008685(Mis12)|refseq:NP_009367.1|sgd:S000000032|mint:P39731|dip:DIP-1464N	-	-	-	figure legend:sf4b|comment:"For this purpose, we used a  version of the Mtw1 complex harbouring a deletion of the  first 171 amino acids of Dsn1 (Dsn1DN); this deletant is  functional in vivo and less prone to degradation in solution  (Hornung et al, 2011). Confirming our hypothesis, the  Ndc8025V159D complex failed to form a 1:1 interaction with  the Mtw1Dsn1DN complex when mixed in equimolar  concentrations (Figure 4B). The same result was observed  for the Ndc8024L160D complex (Supplementary Figure S4),"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/01/07	2014/10/16	rogid:DfxCEgsBR5iDmrfMZEzeaxrZyls559292	rogid:p+tSpERopX07gzW0YKWtjDQg+Tk559292	intact-crc:B893A7FE6F474A24|rigid:x5aDq63JfkDYhlniYYUV2staR18	false	binding-associated region:172-576|his tag:?-?	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P40568	uniprotkb:P40460	intact:EBI-25398|uniprotkb:D6VVU0|ensemblfungi:YIR010W	intact:EBI-25247|uniprotkb:D6VVE3|ensemblfungi:YIL144W	psi-mi:dsn1_yeast(display_long)|uniprotkb:YIB10W(orf name)|uniprotkb:YIR010W(locus name)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)	psi-mi:ndc80_yeast(display_long)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:80 kDa spindle component protein(gene name synonym)|uniprotkb:HEC1(gene name synonym)|uniprotkb:Nuclear division cycle protein 80(gene name synonym)|uniprotkb:TID3(gene name synonym)|uniprotkb:Two-hybrid interaction with DMC1 protein 3(gene name synonym)|uniprotkb:YIL144W(locus name)	psi-mi:"MI:0071"(molecular sieving)	Malvezzi et al. (2013)	pubmed:23334295|imex:IM-22196	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9076935|imex:IM-22196-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001449|refseq:NP_012275.3|mint:P40568|dip:DIP-4794N|ensemblfungi:YIR010W(gene)|ensemblfungi:YIR010W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000922"(spindle pole)|go:"GO:0000939"(inner kinetochore)|go:"GO:0007059"(chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|interpro:IPR018247|rcsb pdb:5T6J|rcsb pdb:6MJE|reactome:R-SCE-6798695	sgd:S000001406|refseq:NP_012122.3|mint:P40460|dip:DIP-818N|ensemblfungi:YIL144W(gene)|ensemblfungi:YIL144W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF	-	-	crc64:7DBC492227A80093	figure legend:sf4b|comment:"For this purpose, we used a  version of the Mtw1 complex harbouring a deletion of the  first 171 amino acids of Dsn1 (Dsn1DN); this deletant is  functional in vivo and less prone to degradation in solution  (Hornung et al, 2011). Confirming our hypothesis, the  Ndc8025V159D complex failed to form a 1:1 interaction with  the Mtw1Dsn1DN complex when mixed in equimolar  concentrations (Figure 4B). The same result was observed  for the Ndc8024L160D complex (Supplementary Figure S4),"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/01/07	2014/10/16	rogid:DfxCEgsBR5iDmrfMZEzeaxrZyls559292	rogid:ZrT7N4pBKz6upSglhGhOqgeoAYw559292	intact-crc:B893A7FE6F474A24|rigid:x5aDq63JfkDYhlniYYUV2staR18	false	binding-associated region:172-576|his tag:?-?	his tag:?-?	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P40568	uniprotkb:P47149	intact:EBI-25398|uniprotkb:D6VVU0|ensemblfungi:YIR010W	intact:EBI-12098|uniprotkb:Q06779|uniprotkb:D6VWT1|ensemblfungi:YJR112W	psi-mi:dsn1_yeast(display_long)|uniprotkb:YIB10W(orf name)|uniprotkb:YIR010W(locus name)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)	psi-mi:nnf1_yeast(display_long)|uniprotkb:J2011(orf name)|uniprotkb:YJR112W(locus name)|uniprotkb:NNF1(gene name)|psi-mi:NNF1(display_short)	psi-mi:"MI:0071"(molecular sieving)	Malvezzi et al. (2013)	pubmed:23334295|imex:IM-22196	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9076935|imex:IM-22196-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001449|refseq:NP_012275.3|mint:P40568|dip:DIP-4794N|ensemblfungi:YIR010W(gene)|ensemblfungi:YIR010W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000922"(spindle pole)|go:"GO:0000939"(inner kinetochore)|go:"GO:0007059"(chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|interpro:IPR018247|rcsb pdb:5T6J|rcsb pdb:6MJE|reactome:R-SCE-6798695	ensemblfungi:YJR112W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0051301"(cell division)|interpro:IPR007128(Nnf1)|interpro:IPR016851(Kinetochore-associated protein Nnf1p)|ensemblfungi:YJR112W(gene)|refseq:NP_012646.3|sgd:S000003873|mint:P47149|dip:DIP-3017N	-	-	-	figure legend:sf4b|comment:"For this purpose, we used a  version of the Mtw1 complex harbouring a deletion of the  first 171 amino acids of Dsn1 (Dsn1DN); this deletant is  functional in vivo and less prone to degradation in solution  (Hornung et al, 2011). Confirming our hypothesis, the  Ndc8025V159D complex failed to form a 1:1 interaction with  the Mtw1Dsn1DN complex when mixed in equimolar  concentrations (Figure 4B). The same result was observed  for the Ndc8024L160D complex (Supplementary Figure S4),"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/01/07	2014/10/16	rogid:DfxCEgsBR5iDmrfMZEzeaxrZyls559292	rogid:fveaY324dma1QT0Cugtm+8PPV2A559292	intact-crc:B893A7FE6F474A24|rigid:x5aDq63JfkDYhlniYYUV2staR18	false	binding-associated region:172-576|his tag:?-?	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P40568	uniprotkb:Q12143	intact:EBI-25398|uniprotkb:D6VVU0|ensemblfungi:YIR010W	intact:EBI-33666|uniprotkb:Q6B152|uniprotkb:D6W3D7|ensemblfungi:YPL233W	psi-mi:dsn1_yeast(display_long)|uniprotkb:YIB10W(orf name)|uniprotkb:YIR010W(locus name)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)	psi-mi:nsl1_yeast(display_long)|uniprotkb:NSL1(gene name)|psi-mi:NSL1(display_short)|uniprotkb:YPL233W(locus name)	psi-mi:"MI:0071"(molecular sieving)	Malvezzi et al. (2013)	pubmed:23334295|imex:IM-22196	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9076935|imex:IM-22196-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001449|refseq:NP_012275.3|mint:P40568|dip:DIP-4794N|ensemblfungi:YIR010W(gene)|ensemblfungi:YIR010W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000922"(spindle pole)|go:"GO:0000939"(inner kinetochore)|go:"GO:0007059"(chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|interpro:IPR018247|rcsb pdb:5T6J|rcsb pdb:6MJE|reactome:R-SCE-6798695	refseq:NP_015091.1|sgd:S000006154|mint:Q12143|dip:DIP-5393N|ensemblfungi:YPL233W(gene)|ensemblfungi:YPL233W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000922"(spindle pole)|go:"GO:0007059"(chromosome segregation)|go:"GO:0051301"(cell division)|interpro:IPR013950(Kinetochore Mis14)	-	-	-	figure legend:sf4b|comment:"For this purpose, we used a  version of the Mtw1 complex harbouring a deletion of the  first 171 amino acids of Dsn1 (Dsn1DN); this deletant is  functional in vivo and less prone to degradation in solution  (Hornung et al, 2011). Confirming our hypothesis, the  Ndc8025V159D complex failed to form a 1:1 interaction with  the Mtw1Dsn1DN complex when mixed in equimolar  concentrations (Figure 4B). The same result was observed  for the Ndc8024L160D complex (Supplementary Figure S4),"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/01/07	2014/10/16	rogid:DfxCEgsBR5iDmrfMZEzeaxrZyls559292	rogid:WAB+WzTulMOWWY5f5mUAmwh3z6o559292	intact-crc:B893A7FE6F474A24|rigid:x5aDq63JfkDYhlniYYUV2staR18	false	binding-associated region:172-576|his tag:?-?	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P40568	uniprotkb:P33895	intact:EBI-25398|uniprotkb:D6VVU0|ensemblfungi:YIR010W	intact:EBI-12377|uniprotkb:Q6B1X5|ensemblfungi:YOL069W|uniprotkb:D6W1Z8	psi-mi:dsn1_yeast(display_long)|uniprotkb:YIB10W(orf name)|uniprotkb:YIR010W(locus name)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)	psi-mi:nuf2_yeast(display_long)|uniprotkb:YOL069W(locus name)|uniprotkb:NUF2(gene name)|psi-mi:NUF2(display_short)	psi-mi:"MI:0071"(molecular sieving)	Malvezzi et al. (2013)	pubmed:23334295|imex:IM-22196	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9076935|imex:IM-22196-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001449|refseq:NP_012275.3|mint:P40568|dip:DIP-4794N|ensemblfungi:YIR010W(gene)|ensemblfungi:YIR010W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000922"(spindle pole)|go:"GO:0000939"(inner kinetochore)|go:"GO:0007059"(chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|interpro:IPR018247|rcsb pdb:5T6J|rcsb pdb:6MJE|reactome:R-SCE-6798695	ensemblfungi:YOL069W(gene)|ensemblfungi:YOL069W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005816"(spindle pole body)|go:"GO:0005876"(spindle microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|interpro:IPR005549(Nuf2)|interpro:IPR038275|rcsb pdb:5TCS|rcsb pdb:5TD8|go:"GO:0045132"(meiotic chromosome segregation)|refseq:NP_014572.1|sgd:S000005430|mint:P33895|dip:DIP-1481N	-	-	-	figure legend:sf4b|comment:"For this purpose, we used a  version of the Mtw1 complex harbouring a deletion of the  first 171 amino acids of Dsn1 (Dsn1DN); this deletant is  functional in vivo and less prone to degradation in solution  (Hornung et al, 2011). Confirming our hypothesis, the  Ndc8025V159D complex failed to form a 1:1 interaction with  the Mtw1Dsn1DN complex when mixed in equimolar  concentrations (Figure 4B). The same result was observed  for the Ndc8024L160D complex (Supplementary Figure S4),"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/01/07	2014/10/16	rogid:DfxCEgsBR5iDmrfMZEzeaxrZyls559292	rogid:oof/8nhKWQCx5bp4lvc7f33OO+0559292	intact-crc:B893A7FE6F474A24|rigid:x5aDq63JfkDYhlniYYUV2staR18	false	binding-associated region:172-576|his tag:?-?	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P40568	uniprotkb:Q04477	intact:EBI-25398|uniprotkb:D6VVU0|ensemblfungi:YIR010W	intact:EBI-27228|uniprotkb:D6VZU0|ensemblfungi:YMR117C	psi-mi:dsn1_yeast(display_long)|uniprotkb:YIB10W(orf name)|uniprotkb:YIR010W(locus name)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)	psi-mi:spc24_yeast(display_long)|uniprotkb:SPC24(gene name)|psi-mi:SPC24(display_short)|uniprotkb:YM9718.16C(orf name)|uniprotkb:YMR117C(locus name)	psi-mi:"MI:0071"(molecular sieving)	Malvezzi et al. (2013)	pubmed:23334295|imex:IM-22196	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9076935|imex:IM-22196-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001449|refseq:NP_012275.3|mint:P40568|dip:DIP-4794N|ensemblfungi:YIR010W(gene)|ensemblfungi:YIR010W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000922"(spindle pole)|go:"GO:0000939"(inner kinetochore)|go:"GO:0007059"(chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|interpro:IPR018247|rcsb pdb:5T6J|rcsb pdb:6MJE|reactome:R-SCE-6798695	refseq:NP_013835.1|sgd:S000004723|mint:Q04477|dip:DIP-893N|ensemblfungi:YMR117C(gene)|ensemblfungi:YMR117C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF	-	-	crc64:8BE4B8619DD4C8FB	figure legend:sf4b|comment:"For this purpose, we used a  version of the Mtw1 complex harbouring a deletion of the  first 171 amino acids of Dsn1 (Dsn1DN); this deletant is  functional in vivo and less prone to degradation in solution  (Hornung et al, 2011). Confirming our hypothesis, the  Ndc8025V159D complex failed to form a 1:1 interaction with  the Mtw1Dsn1DN complex when mixed in equimolar  concentrations (Figure 4B). The same result was observed  for the Ndc8024L160D complex (Supplementary Figure S4),"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/01/07	2014/10/16	rogid:DfxCEgsBR5iDmrfMZEzeaxrZyls559292	rogid:B12w0JvNs2He1WjK6c241nF3pZc559292	intact-crc:B893A7FE6F474A24|rigid:x5aDq63JfkDYhlniYYUV2staR18	false	binding-associated region:172-576|his tag:?-?	his tag:?-?|mutation disrupting interaction:160-160	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P40568	uniprotkb:P40014	intact:EBI-25398|uniprotkb:D6VVU0|ensemblfungi:YIR010W	intact:EBI-22458|uniprotkb:D3DLR6|ensemblfungi:YER018C	psi-mi:dsn1_yeast(display_long)|uniprotkb:YIB10W(orf name)|uniprotkb:YIR010W(locus name)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)	psi-mi:spc25_yeast(display_long)|uniprotkb:YER018C(locus name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short)	psi-mi:"MI:0071"(molecular sieving)	Malvezzi et al. (2013)	pubmed:23334295|imex:IM-22196	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9076935|imex:IM-22196-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001449|refseq:NP_012275.3|mint:P40568|dip:DIP-4794N|ensemblfungi:YIR010W(gene)|ensemblfungi:YIR010W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000922"(spindle pole)|go:"GO:0000939"(inner kinetochore)|go:"GO:0007059"(chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|interpro:IPR018247|rcsb pdb:5T6J|rcsb pdb:6MJE|reactome:R-SCE-6798695	refseq:NP_010934.3|sgd:S000000820|dip:DIP-2990N|mint:P40014|ensemblfungi:YER018C(gene)|ensemblfungi:YER018C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF	-	-	crc64:1BED6CCFF330A5D8	figure legend:sf4b|comment:"For this purpose, we used a  version of the Mtw1 complex harbouring a deletion of the  first 171 amino acids of Dsn1 (Dsn1DN); this deletant is  functional in vivo and less prone to degradation in solution  (Hornung et al, 2011). Confirming our hypothesis, the  Ndc8025V159D complex failed to form a 1:1 interaction with  the Mtw1Dsn1DN complex when mixed in equimolar  concentrations (Figure 4B). The same result was observed  for the Ndc8024L160D complex (Supplementary Figure S4),"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/01/07	2014/10/16	rogid:DfxCEgsBR5iDmrfMZEzeaxrZyls559292	rogid:i5gKRZA7GAjnCVzuX/qP8YmpQRA559292	intact-crc:B893A7FE6F474A24|rigid:x5aDq63JfkDYhlniYYUV2staR18	false	binding-associated region:172-576|his tag:?-?	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P40568	uniprotkb:P39731	intact:EBI-25398|uniprotkb:D6VVU0|ensemblfungi:YIR010W	intact:EBI-11606|uniprotkb:D6VPI3|ensemblfungi:YAL034W-A	psi-mi:dsn1_yeast(display_long)|uniprotkb:YIB10W(orf name)|uniprotkb:YIR010W(locus name)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)	psi-mi:mtw1_yeast(display_long)|uniprotkb:MTW1(gene name)|psi-mi:MTW1(display_short)|uniprotkb:YAL034W-A(locus name)|uniprotkb:YAL034AW(orf name)|uniprotkb:DSN3(gene name synonym)|uniprotkb:NSL2(gene name synonym)|uniprotkb:Mis12-like protein(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Malvezzi et al. (2013)	pubmed:23334295|imex:IM-22196	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9076832|imex:IM-22196-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001449|refseq:NP_012275.3|mint:P40568|dip:DIP-4794N|ensemblfungi:YIR010W(gene)|ensemblfungi:YIR010W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000922"(spindle pole)|go:"GO:0000939"(inner kinetochore)|go:"GO:0007059"(chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|interpro:IPR018247|rcsb pdb:5T6J|rcsb pdb:6MJE|reactome:R-SCE-6798695	ensemblfungi:YAL034W-A(gene)|ensemblfungi:YAL034W-A_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR008685(Mis12)|refseq:NP_009367.1|sgd:S000000032|mint:P39731|dip:DIP-1464N	-	-	-	figure legend:f4b|comment:"For this purpose, we used a  version of the Mtw1 complex harbouring a deletion of the  first 171 amino acids of Dsn1 (Dsn1DN); this deletant is  functional in vivo and less prone to degradation in solution  (Hornung et al, 2011). Confirming our hypothesis, the  Ndc8025V159D complex failed to form a 1:1 interaction with  the Mtw1Dsn1DN complex when mixed in equimolar  concentrations (Figure 4B). The same result was observed  for the Ndc8024L160D complex (Supplementary Figure S4),"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/01/07	2014/10/16	rogid:DfxCEgsBR5iDmrfMZEzeaxrZyls559292	rogid:p+tSpERopX07gzW0YKWtjDQg+Tk559292	intact-crc:0FB17D942199E6D2|rigid:x5aDq63JfkDYhlniYYUV2staR18	false	his tag:?-?|binding-associated region:172-576	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P40568	uniprotkb:P40460	intact:EBI-25398|uniprotkb:D6VVU0|ensemblfungi:YIR010W	intact:EBI-25247|uniprotkb:D6VVE3|ensemblfungi:YIL144W	psi-mi:dsn1_yeast(display_long)|uniprotkb:YIB10W(orf name)|uniprotkb:YIR010W(locus name)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)	psi-mi:ndc80_yeast(display_long)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:80 kDa spindle component protein(gene name synonym)|uniprotkb:HEC1(gene name synonym)|uniprotkb:Nuclear division cycle protein 80(gene name synonym)|uniprotkb:TID3(gene name synonym)|uniprotkb:Two-hybrid interaction with DMC1 protein 3(gene name synonym)|uniprotkb:YIL144W(locus name)	psi-mi:"MI:0071"(molecular sieving)	Malvezzi et al. (2013)	pubmed:23334295|imex:IM-22196	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9076832|imex:IM-22196-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001449|refseq:NP_012275.3|mint:P40568|dip:DIP-4794N|ensemblfungi:YIR010W(gene)|ensemblfungi:YIR010W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000922"(spindle pole)|go:"GO:0000939"(inner kinetochore)|go:"GO:0007059"(chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|interpro:IPR018247|rcsb pdb:5T6J|rcsb pdb:6MJE|reactome:R-SCE-6798695	sgd:S000001406|refseq:NP_012122.3|mint:P40460|dip:DIP-818N|ensemblfungi:YIL144W(gene)|ensemblfungi:YIL144W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF	-	-	crc64:7DBC492227A80093	figure legend:f4b|comment:"For this purpose, we used a  version of the Mtw1 complex harbouring a deletion of the  first 171 amino acids of Dsn1 (Dsn1DN); this deletant is  functional in vivo and less prone to degradation in solution  (Hornung et al, 2011). Confirming our hypothesis, the  Ndc8025V159D complex failed to form a 1:1 interaction with  the Mtw1Dsn1DN complex when mixed in equimolar  concentrations (Figure 4B). The same result was observed  for the Ndc8024L160D complex (Supplementary Figure S4),"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/01/07	2014/10/16	rogid:DfxCEgsBR5iDmrfMZEzeaxrZyls559292	rogid:ZrT7N4pBKz6upSglhGhOqgeoAYw559292	intact-crc:0FB17D942199E6D2|rigid:x5aDq63JfkDYhlniYYUV2staR18	false	his tag:?-?|binding-associated region:172-576	his tag:?-?	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P40568	uniprotkb:P47149	intact:EBI-25398|uniprotkb:D6VVU0|ensemblfungi:YIR010W	intact:EBI-12098|uniprotkb:Q06779|uniprotkb:D6VWT1|ensemblfungi:YJR112W	psi-mi:dsn1_yeast(display_long)|uniprotkb:YIB10W(orf name)|uniprotkb:YIR010W(locus name)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)	psi-mi:nnf1_yeast(display_long)|uniprotkb:J2011(orf name)|uniprotkb:YJR112W(locus name)|uniprotkb:NNF1(gene name)|psi-mi:NNF1(display_short)	psi-mi:"MI:0071"(molecular sieving)	Malvezzi et al. (2013)	pubmed:23334295|imex:IM-22196	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9076832|imex:IM-22196-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001449|refseq:NP_012275.3|mint:P40568|dip:DIP-4794N|ensemblfungi:YIR010W(gene)|ensemblfungi:YIR010W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000922"(spindle pole)|go:"GO:0000939"(inner kinetochore)|go:"GO:0007059"(chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|interpro:IPR018247|rcsb pdb:5T6J|rcsb pdb:6MJE|reactome:R-SCE-6798695	ensemblfungi:YJR112W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0051301"(cell division)|interpro:IPR007128(Nnf1)|interpro:IPR016851(Kinetochore-associated protein Nnf1p)|ensemblfungi:YJR112W(gene)|refseq:NP_012646.3|sgd:S000003873|mint:P47149|dip:DIP-3017N	-	-	-	figure legend:f4b|comment:"For this purpose, we used a  version of the Mtw1 complex harbouring a deletion of the  first 171 amino acids of Dsn1 (Dsn1DN); this deletant is  functional in vivo and less prone to degradation in solution  (Hornung et al, 2011). Confirming our hypothesis, the  Ndc8025V159D complex failed to form a 1:1 interaction with  the Mtw1Dsn1DN complex when mixed in equimolar  concentrations (Figure 4B). The same result was observed  for the Ndc8024L160D complex (Supplementary Figure S4),"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/01/07	2014/10/16	rogid:DfxCEgsBR5iDmrfMZEzeaxrZyls559292	rogid:fveaY324dma1QT0Cugtm+8PPV2A559292	intact-crc:0FB17D942199E6D2|rigid:x5aDq63JfkDYhlniYYUV2staR18	false	his tag:?-?|binding-associated region:172-576	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P40568	uniprotkb:Q12143	intact:EBI-25398|uniprotkb:D6VVU0|ensemblfungi:YIR010W	intact:EBI-33666|uniprotkb:Q6B152|uniprotkb:D6W3D7|ensemblfungi:YPL233W	psi-mi:dsn1_yeast(display_long)|uniprotkb:YIB10W(orf name)|uniprotkb:YIR010W(locus name)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)	psi-mi:nsl1_yeast(display_long)|uniprotkb:NSL1(gene name)|psi-mi:NSL1(display_short)|uniprotkb:YPL233W(locus name)	psi-mi:"MI:0071"(molecular sieving)	Malvezzi et al. (2013)	pubmed:23334295|imex:IM-22196	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9076832|imex:IM-22196-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001449|refseq:NP_012275.3|mint:P40568|dip:DIP-4794N|ensemblfungi:YIR010W(gene)|ensemblfungi:YIR010W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000922"(spindle pole)|go:"GO:0000939"(inner kinetochore)|go:"GO:0007059"(chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|interpro:IPR018247|rcsb pdb:5T6J|rcsb pdb:6MJE|reactome:R-SCE-6798695	refseq:NP_015091.1|sgd:S000006154|mint:Q12143|dip:DIP-5393N|ensemblfungi:YPL233W(gene)|ensemblfungi:YPL233W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000922"(spindle pole)|go:"GO:0007059"(chromosome segregation)|go:"GO:0051301"(cell division)|interpro:IPR013950(Kinetochore Mis14)	-	-	-	figure legend:f4b|comment:"For this purpose, we used a  version of the Mtw1 complex harbouring a deletion of the  first 171 amino acids of Dsn1 (Dsn1DN); this deletant is  functional in vivo and less prone to degradation in solution  (Hornung et al, 2011). Confirming our hypothesis, the  Ndc8025V159D complex failed to form a 1:1 interaction with  the Mtw1Dsn1DN complex when mixed in equimolar  concentrations (Figure 4B). The same result was observed  for the Ndc8024L160D complex (Supplementary Figure S4),"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/01/07	2014/10/16	rogid:DfxCEgsBR5iDmrfMZEzeaxrZyls559292	rogid:WAB+WzTulMOWWY5f5mUAmwh3z6o559292	intact-crc:0FB17D942199E6D2|rigid:x5aDq63JfkDYhlniYYUV2staR18	false	his tag:?-?|binding-associated region:172-576	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P40568	uniprotkb:P33895	intact:EBI-25398|uniprotkb:D6VVU0|ensemblfungi:YIR010W	intact:EBI-12377|uniprotkb:Q6B1X5|ensemblfungi:YOL069W|uniprotkb:D6W1Z8	psi-mi:dsn1_yeast(display_long)|uniprotkb:YIB10W(orf name)|uniprotkb:YIR010W(locus name)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)	psi-mi:nuf2_yeast(display_long)|uniprotkb:YOL069W(locus name)|uniprotkb:NUF2(gene name)|psi-mi:NUF2(display_short)	psi-mi:"MI:0071"(molecular sieving)	Malvezzi et al. (2013)	pubmed:23334295|imex:IM-22196	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9076832|imex:IM-22196-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001449|refseq:NP_012275.3|mint:P40568|dip:DIP-4794N|ensemblfungi:YIR010W(gene)|ensemblfungi:YIR010W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000922"(spindle pole)|go:"GO:0000939"(inner kinetochore)|go:"GO:0007059"(chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|interpro:IPR018247|rcsb pdb:5T6J|rcsb pdb:6MJE|reactome:R-SCE-6798695	ensemblfungi:YOL069W(gene)|ensemblfungi:YOL069W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005816"(spindle pole body)|go:"GO:0005876"(spindle microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|interpro:IPR005549(Nuf2)|interpro:IPR038275|rcsb pdb:5TCS|rcsb pdb:5TD8|go:"GO:0045132"(meiotic chromosome segregation)|refseq:NP_014572.1|sgd:S000005430|mint:P33895|dip:DIP-1481N	-	-	-	figure legend:f4b|comment:"For this purpose, we used a  version of the Mtw1 complex harbouring a deletion of the  first 171 amino acids of Dsn1 (Dsn1DN); this deletant is  functional in vivo and less prone to degradation in solution  (Hornung et al, 2011). Confirming our hypothesis, the  Ndc8025V159D complex failed to form a 1:1 interaction with  the Mtw1Dsn1DN complex when mixed in equimolar  concentrations (Figure 4B). The same result was observed  for the Ndc8024L160D complex (Supplementary Figure S4),"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/01/07	2014/10/16	rogid:DfxCEgsBR5iDmrfMZEzeaxrZyls559292	rogid:oof/8nhKWQCx5bp4lvc7f33OO+0559292	intact-crc:0FB17D942199E6D2|rigid:x5aDq63JfkDYhlniYYUV2staR18	false	his tag:?-?|binding-associated region:172-576	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P40568	uniprotkb:Q04477	intact:EBI-25398|uniprotkb:D6VVU0|ensemblfungi:YIR010W	intact:EBI-27228|uniprotkb:D6VZU0|ensemblfungi:YMR117C	psi-mi:dsn1_yeast(display_long)|uniprotkb:YIB10W(orf name)|uniprotkb:YIR010W(locus name)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)	psi-mi:spc24_yeast(display_long)|uniprotkb:SPC24(gene name)|psi-mi:SPC24(display_short)|uniprotkb:YM9718.16C(orf name)|uniprotkb:YMR117C(locus name)	psi-mi:"MI:0071"(molecular sieving)	Malvezzi et al. (2013)	pubmed:23334295|imex:IM-22196	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9076832|imex:IM-22196-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001449|refseq:NP_012275.3|mint:P40568|dip:DIP-4794N|ensemblfungi:YIR010W(gene)|ensemblfungi:YIR010W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000922"(spindle pole)|go:"GO:0000939"(inner kinetochore)|go:"GO:0007059"(chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|interpro:IPR018247|rcsb pdb:5T6J|rcsb pdb:6MJE|reactome:R-SCE-6798695	refseq:NP_013835.1|sgd:S000004723|mint:Q04477|dip:DIP-893N|ensemblfungi:YMR117C(gene)|ensemblfungi:YMR117C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF	-	-	crc64:8BE4B8619DD4C8FB	figure legend:f4b|comment:"For this purpose, we used a  version of the Mtw1 complex harbouring a deletion of the  first 171 amino acids of Dsn1 (Dsn1DN); this deletant is  functional in vivo and less prone to degradation in solution  (Hornung et al, 2011). Confirming our hypothesis, the  Ndc8025V159D complex failed to form a 1:1 interaction with  the Mtw1Dsn1DN complex when mixed in equimolar  concentrations (Figure 4B). The same result was observed  for the Ndc8024L160D complex (Supplementary Figure S4),"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/01/07	2014/10/16	rogid:DfxCEgsBR5iDmrfMZEzeaxrZyls559292	rogid:B12w0JvNs2He1WjK6c241nF3pZc559292	intact-crc:0FB17D942199E6D2|rigid:x5aDq63JfkDYhlniYYUV2staR18	false	his tag:?-?|binding-associated region:172-576	his tag:?-?	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P40568	uniprotkb:P40014	intact:EBI-25398|uniprotkb:D6VVU0|ensemblfungi:YIR010W	intact:EBI-22458|uniprotkb:D3DLR6|ensemblfungi:YER018C	psi-mi:dsn1_yeast(display_long)|uniprotkb:YIB10W(orf name)|uniprotkb:YIR010W(locus name)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)	psi-mi:spc25_yeast(display_long)|uniprotkb:YER018C(locus name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short)	psi-mi:"MI:0071"(molecular sieving)	Malvezzi et al. (2013)	pubmed:23334295|imex:IM-22196	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9076832|imex:IM-22196-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001449|refseq:NP_012275.3|mint:P40568|dip:DIP-4794N|ensemblfungi:YIR010W(gene)|ensemblfungi:YIR010W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000922"(spindle pole)|go:"GO:0000939"(inner kinetochore)|go:"GO:0007059"(chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|interpro:IPR018247|rcsb pdb:5T6J|rcsb pdb:6MJE|reactome:R-SCE-6798695	refseq:NP_010934.3|sgd:S000000820|dip:DIP-2990N|mint:P40014|ensemblfungi:YER018C(gene)|ensemblfungi:YER018C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF	-	-	crc64:1BED6CCFF330A5D8	figure legend:f4b|comment:"For this purpose, we used a  version of the Mtw1 complex harbouring a deletion of the  first 171 amino acids of Dsn1 (Dsn1DN); this deletant is  functional in vivo and less prone to degradation in solution  (Hornung et al, 2011). Confirming our hypothesis, the  Ndc8025V159D complex failed to form a 1:1 interaction with  the Mtw1Dsn1DN complex when mixed in equimolar  concentrations (Figure 4B). The same result was observed  for the Ndc8024L160D complex (Supplementary Figure S4),"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/01/07	2014/10/16	rogid:DfxCEgsBR5iDmrfMZEzeaxrZyls559292	rogid:i5gKRZA7GAjnCVzuX/qP8YmpQRA559292	intact-crc:0FB17D942199E6D2|rigid:x5aDq63JfkDYhlniYYUV2staR18	false	his tag:?-?|binding-associated region:172-576	mutation disrupting interaction:159-159	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P40014	uniprotkb:Q04477	intact:EBI-22458|uniprotkb:D3DLR6|ensemblfungi:YER018C	intact:EBI-27228|uniprotkb:D6VZU0|ensemblfungi:YMR117C	psi-mi:spc25_yeast(display_long)|uniprotkb:YER018C(locus name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short)	psi-mi:spc24_yeast(display_long)|uniprotkb:SPC24(gene name)|psi-mi:SPC24(display_short)|uniprotkb:YM9718.16C(orf name)|uniprotkb:YMR117C(locus name)	psi-mi:"MI:0071"(molecular sieving)	Malvezzi et al. (2013)	pubmed:23334295|imex:IM-22196	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9076422|imex:IM-22196-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010934.3|sgd:S000000820|dip:DIP-2990N|mint:P40014|ensemblfungi:YER018C(gene)|ensemblfungi:YER018C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF	refseq:NP_013835.1|sgd:S000004723|mint:Q04477|dip:DIP-893N|ensemblfungi:YMR117C(gene)|ensemblfungi:YMR117C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF	-	crc64:1BED6CCFF330A5D8	crc64:8BE4B8619DD4C8FB	figure legend:f3b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/01/07	2014/10/16	rogid:i5gKRZA7GAjnCVzuX/qP8YmpQRA559292	rogid:B12w0JvNs2He1WjK6c241nF3pZc559292	intact-crc:90F9EB3241BC20D1|rigid:kFcOWWSr5XGaZIDaoMeh05/UAGU	false	binding-associated region:133-221	binding-associated region:155-213	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P33895	uniprotkb:P43618	intact:EBI-12377|uniprotkb:Q6B1X5|ensemblfungi:YOL069W|uniprotkb:D6W1Z8	intact:EBI-23036|uniprotkb:D6VTS9|uniprotkb:Q6B2K8|ensemblfungi:YFR046C	psi-mi:nuf2_yeast(display_long)|uniprotkb:YOL069W(locus name)|uniprotkb:NUF2(gene name)|psi-mi:NUF2(display_short)	psi-mi:cenpt_yeast(display_long)|uniprotkb:CNN1(gene name)|psi-mi:CNN1(display_short)|uniprotkb:Co-purified with NNF1 protein 1(gene name synonym)|uniprotkb:CENP-T homolog(gene name synonym)|uniprotkb:Constitutive centromere-associated network protein CNN1(gene name synonym)|uniprotkb:YFR046C(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Malvezzi et al. (2013)	pubmed:23334295|imex:IM-22196	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9077065|imex:IM-22196-16	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YOL069W(gene)|ensemblfungi:YOL069W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005816"(spindle pole body)|go:"GO:0005876"(spindle microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|interpro:IPR005549(Nuf2)|interpro:IPR038275|rcsb pdb:5TCS|rcsb pdb:5TD8|go:"GO:0045132"(meiotic chromosome segregation)|refseq:NP_014572.1|sgd:S000005430|mint:P33895|dip:DIP-1481N	sgd:S000001942|refseq:NP_116704.1|dip:DIP-5186N|ensemblfungi:YFR046C(gene)|ensemblfungi:YFR046C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:1901720"(negative regulation of NMS complex assembly)|rcsb pdb:4GEQ|rcsb pdb:6WUC|rcsb pdb:6YPC	-	-	crc64:48CEEC087A056D42	figure legend:f6h|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2014/01/07	2014/10/16	rogid:oof/8nhKWQCx5bp4lvc7f33OO+0559292	rogid:Pkvt7uOWT2WqZlcWh8NeZH67Mvs559292	intact-crc:0E8758639D4FA883|rigid:INo+l9pmfn0rmmPntVleWqxfNTI	false	myc tag:?-?	flag tag:?-?|mutation disrupting interaction:74-74	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P33895	uniprotkb:P43618	intact:EBI-12377|uniprotkb:Q6B1X5|ensemblfungi:YOL069W|uniprotkb:D6W1Z8	intact:EBI-23036|uniprotkb:D6VTS9|uniprotkb:Q6B2K8|ensemblfungi:YFR046C	psi-mi:nuf2_yeast(display_long)|uniprotkb:YOL069W(locus name)|uniprotkb:NUF2(gene name)|psi-mi:NUF2(display_short)	psi-mi:cenpt_yeast(display_long)|uniprotkb:CNN1(gene name)|psi-mi:CNN1(display_short)|uniprotkb:Co-purified with NNF1 protein 1(gene name synonym)|uniprotkb:CENP-T homolog(gene name synonym)|uniprotkb:Constitutive centromere-associated network protein CNN1(gene name synonym)|uniprotkb:YFR046C(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Malvezzi et al. (2013)	pubmed:23334295|imex:IM-22196	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9077081|imex:IM-22196-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YOL069W(gene)|ensemblfungi:YOL069W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005816"(spindle pole body)|go:"GO:0005876"(spindle microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|interpro:IPR005549(Nuf2)|interpro:IPR038275|rcsb pdb:5TCS|rcsb pdb:5TD8|go:"GO:0045132"(meiotic chromosome segregation)|refseq:NP_014572.1|sgd:S000005430|mint:P33895|dip:DIP-1481N	sgd:S000001942|refseq:NP_116704.1|dip:DIP-5186N|ensemblfungi:YFR046C(gene)|ensemblfungi:YFR046C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:1901720"(negative regulation of NMS complex assembly)|rcsb pdb:4GEQ|rcsb pdb:6WUC|rcsb pdb:6YPC	-	-	crc64:48CEEC087A056D42	figure legend:f7b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2014/01/07	2014/10/16	rogid:oof/8nhKWQCx5bp4lvc7f33OO+0559292	rogid:Pkvt7uOWT2WqZlcWh8NeZH67Mvs559292	intact-crc:881D913B95038736|rigid:INo+l9pmfn0rmmPntVleWqxfNTI	false	myc tag:?-?	mutation increasing interaction:16-16|flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)