#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P62942 uniprotkb:P42345 intact:EBI-1027571|uniprotkb:P20071|uniprotkb:Q4VC47|uniprotkb:Q6FGD9|uniprotkb:Q6LEU3|uniprotkb:Q9H103|uniprotkb:Q9H566|uniprotkb:D3DVW6|ensembl:ENSP00000371138|ensembl:ENSP00000371143|ensembl:ENSP00000383003|ensembl:ENSP00000503033|ensembl:ENSP00000503152 intact:EBI-359260|uniprotkb:Q5TER1|uniprotkb:Q4LE76|uniprotkb:Q6LE87|uniprotkb:Q96QG3|uniprotkb:Q9Y4I3|ensembl:ENSP00000354558|intact:EBI-28989074 psi-mi:fkb1a_human(display_long)|uniprotkb:FKBP1A(gene name)|psi-mi:FKBP1A(display_short)|uniprotkb:FKBP1(gene name synonym)|uniprotkb:FKBP12(gene name synonym)|uniprotkb:FK506-binding protein 1A(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:Immunophilin FKBP12(gene name synonym)|uniprotkb:12 kDa FK506-binding protein(gene name synonym)|uniprotkb:Calstabin-1(gene name synonym) psi-mi:mtor_human(display_long)|uniprotkb:MTOR(gene name)|psi-mi:MTOR(display_short)|uniprotkb:FRAP(gene name synonym)|uniprotkb:FRAP2(gene name synonym)|uniprotkb:FK506-binding protein 12-rapamycin complex-associated protein 1(gene name synonym)|uniprotkb:Rapamycin target protein 1(gene name synonym)|uniprotkb:FRAP1(gene name synonym)|uniprotkb:Mammalian target of rapamycin(gene name synonym)|uniprotkb:FKBP12-rapamycin complex-associated protein(gene name synonym)|uniprotkb:Mechanistic target of rapamycin(gene name synonym)|uniprotkb:RAFT1(gene name synonym)|uniprotkb:RAPT1(gene name synonym)|uniprotkb:Rapamycin and FKBP12 target 1(gene name synonym) psi-mi:"MI:0813"(proximity ligation assay) Gu et al. (2013) imex:IM-22069|pubmed:22664266 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0469"(IntAct) intact:EBI-9120172|imex:IM-22069-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000088832(gene)|ensembl:ENST00000381719(transcript)|ensembl:ENST00000381724(transcript)|ensembl:ENST00000400137(transcript)|ensembl:ENST00000677335(transcript)|ensembl:ENST00000678408(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005527"(macrolide binding)|go:"GO:0005528"(FK506 binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0014802"(terminal cisterna)|go:"GO:0016020"(membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030018"(Z disc)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031312"(extrinsic component of organelle membrane)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032925"(regulation of activin receptor signaling pathway)|go:"GO:0034713"(type I transforming growth factor beta receptor binding)|go:"GO:0042026"(protein refolding)|go:"GO:0042110"(T cell activation)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046332"(SMAD binding)|go:"GO:0048185"(activin binding)|go:"GO:0050776"(regulation of immune response)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:1902991"(regulation of amyloid precursor protein catabolic process)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990425"(ryanodine receptor complex)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|rcsb pdb:1A7X|rcsb pdb:1B6C|rcsb pdb:1BKF|rcsb pdb:1BL4|rcsb pdb:1D6O|rcsb pdb:1D7H|rcsb pdb:1D7I|rcsb pdb:1D7J|rcsb pdb:1EYM|rcsb pdb:1F40|rcsb pdb:1FAP|rcsb pdb:1FKB|rcsb pdb:1FKD|rcsb pdb:1FKF|rcsb pdb:1FKG|rcsb pdb:1FKH|rcsb pdb:1FKI|rcsb pdb:2DG4|rcsb pdb:2DG9|rcsb pdb:2FAP|rcsb pdb:2FKE|rcsb pdb:2ND5|rcsb pdb:2PPN|rcsb pdb:2PPO|rcsb pdb:2PPP|rcsb pdb:2RSE|rcsb pdb:3FAP|rcsb pdb:1FKJ|rcsb pdb:3H9R|rcsb pdb:3MDY|rcsb pdb:4DH0|rcsb pdb:4FAP|rcsb pdb:1FKR|rcsb pdb:4IPX|rcsb pdb:4N19|rcsb pdb:4ODP|rcsb pdb:4ODQ|rcsb pdb:4ODR|rcsb pdb:5I7P|rcsb pdb:5I7Q|rcsb pdb:6I1S|rcsb pdb:1FKS|rcsb pdb:6M4U|rcsb pdb:6OQA|rcsb pdb:6VCU|rcsb pdb:6YF0|rcsb pdb:6YF1|rcsb pdb:6YF2|rcsb pdb:6YF3|reactome:R-HSA-166208|rcsb pdb:1FKT|reactome:R-HSA-2025928|reactome:R-HSA-2173789|reactome:R-HSA-2173791|reactome:R-HSA-3656535|rcsb pdb:1J4H|rcsb pdb:1J4I|reactome:R-HSA-9679191|rcsb pdb:1J4R|rcsb pdb:1NSG|rcsb pdb:1QPF|rcsb pdb:1QPL|rcsb pdb:2DG3|refseq:NP_000792.1|refseq:NP_463460.1|dip:DIP-29710N ensembl:ENSG00000198793(gene)|refseq:NP_004949.1|ensembl:ENST00000361445(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001002"(RNA polymerase III type 1 promoter sequence-specific DNA binding)|go:"GO:0001003"(RNA polymerase III type 2 promoter sequence-specific DNA binding)|go:"GO:0001006"(RNA polymerase III type 3 promoter sequence-specific DNA binding)|go:"GO:0001156"(TFIIIC-class transcription factor complex binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002296"(T-helper 1 cell lineage commitment)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003179"(heart valve morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005764"(lysosome)|rcsb pdb:6SB0|rcsb pdb:6SB2|rcsb pdb:6ZWM|rcsb pdb:6ZWO|reactome:R-HSA-1257604|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-3371571|reactome:R-HSA-380972|reactome:R-HSA-389357|reactome:R-HSA-5218920|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-6804757|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0012505"(endomembrane system)|go:"GO:0014042"(positive regulation of neuron maturation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030425"(dendrite)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031529"(ruffle organization)|go:"GO:0031641"(regulation of myelination)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0031929"(TOR signaling)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0031998"(regulation of fatty acid beta-oxidation)|go:"GO:0032095"(regulation of response to food)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035176"(social behavior)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0042060"(wound healing)|go:"GO:0042220"(response to cocaine)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043200"(response to amino acid)|go:"GO:0043276"(anoikis)|go:"GO:0043278"(response to morphine)|go:"GO:0043610"(regulation of carbohydrate utilization)|go:"GO:0045182"(translation regulator activity)|go:"GO:0014736"(negative regulation of muscle atrophy)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048511"(rhythmic process)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071233"(cellular response to leucine)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090335"(regulation of brown fat cell differentiation)|go:"GO:0090559"(regulation of membrane permeability)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099547"(regulation of translation at synapse, modulating synaptic transmission)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900034"(regulation of cellular response to heat)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1903691"(positive regulation of wound healing, spreading of epidermal cells)|go:"GO:1904000"(positive regulation of eating behavior)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0008542"(visual learning)|go:"GO:1904058"(positive regulation of sensory perception of pain)|go:"GO:1904059"(regulation of locomotor rhythm)|go:"GO:1904193"(negative regulation of cholangiocyte apoptotic process)|go:"GO:1904197"(positive regulation of granulosa cell proliferation)|go:"GO:1904206"(positive regulation of skeletal muscle hypertrophy)|go:"GO:1904213"(negative regulation of iodide transmembrane transport)|go:"GO:1904690"(positive regulation of cytoplasmic translational initiation)|go:"GO:1990253"(cellular response to leucine starvation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR024585|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940|mint:P42345|go:"GO:1904056"(positive regulation of cholangiocyte proliferation)|rcsb pdb:1FAP|rcsb pdb:1NSG|rcsb pdb:2FAP|rcsb pdb:2GAQ|rcsb pdb:2NPU|rcsb pdb:2RSE|rcsb pdb:3FAP|rcsb pdb:3JBZ|rcsb pdb:4DRH|rcsb pdb:4DRI|rcsb pdb:4DRJ|rcsb pdb:4FAP|rcsb pdb:4JSN|rcsb pdb:4JSP|rcsb pdb:4JSV|rcsb pdb:4JSX|rcsb pdb:4JT5|rcsb pdb:4JT6|rcsb pdb:5FLC|rcsb pdb:5GPG|rcsb pdb:5H64|rcsb pdb:5WBH|rcsb pdb:5WBU|rcsb pdb:5WBY|rcsb pdb:5ZCS|rcsb pdb:6BCU|rcsb pdb:1AUE|rcsb pdb:6BCX|rcsb pdb:6M4U|rcsb pdb:6M4W|go:"GO:0005789"(endoplasmic reticulum membrane)|ensembl:ENSP00000354558|refseq:XP_005263495.1|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005829"(cytosol)|go:"GO:0007040"(lysosome organization)|go:"GO:0007281"(germ cell development)|go:"GO:0007420"(brain development)|go:"GO:0007569"(cell aging)|go:"GO:0007584"(response to nutrient)|go:"GO:0007616"(long-term memory)|go:"GO:0008361"(regulation of cell size)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006468"(protein phosphorylation)|dip:DIP-790N - - - figure legend:4|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/02/07 2014/10/16 rogid:3eikHNIIVs8AFM7PYVWurI/9KUY9606 rogid:z6uJxqv906jKZ7IqoavN5JTWJs09606 intact-crc:EC7D6EFF034BB054 false tag:?-? tag:?-?|sufficient binding region:2012..2025-2114..2144 - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) chebi:"CHEBI:9168" uniprotkb:P62942 intact:EBI-9120221|chebi:"CHEBI:100923"|chebi:"CHEBI:67812" intact:EBI-1027571|uniprotkb:P20071|uniprotkb:Q4VC47|uniprotkb:Q6FGD9|uniprotkb:Q6LEU3|uniprotkb:Q9H103|uniprotkb:Q9H566|uniprotkb:D3DVW6|ensembl:ENSP00000371138|ensembl:ENSP00000371143|ensembl:ENSP00000383003|ensembl:ENSP00000503033|ensembl:ENSP00000503152 psi-mi:sirolimus(display_short)|psi-mi:"CHEBI:9168"(display_long)|intact:"(-)-Rapamycin"(synonym)|intact:"(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-{(2S)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl}-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.0(4,9)]hexatriaconta-16,24,26,28-tetr"(synonym)|intact:Antibiotic AY 22989(synonym)|intact:Rapamune(synonym)|intact:rapamycin(synonym)|intact:sirolimus(synonym)|intact:Sirolimus(synonym)|intact:sirolimusum(synonym)|intact:"(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-3-{(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epo"(iupac name) psi-mi:fkb1a_human(display_long)|uniprotkb:FKBP1A(gene name)|psi-mi:FKBP1A(display_short)|uniprotkb:FKBP1(gene name synonym)|uniprotkb:FKBP12(gene name synonym)|uniprotkb:FK506-binding protein 1A(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:Immunophilin FKBP12(gene name synonym)|uniprotkb:12 kDa FK506-binding protein(gene name synonym)|uniprotkb:Calstabin-1(gene name synonym) psi-mi:"MI:0813"(proximity ligation assay) Gu et al. (2013) imex:IM-22069|pubmed:22664266 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0469"(IntAct) intact:EBI-9120172|imex:IM-22069-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000088832(gene)|ensembl:ENST00000381719(transcript)|ensembl:ENST00000381724(transcript)|ensembl:ENST00000400137(transcript)|ensembl:ENST00000677335(transcript)|ensembl:ENST00000678408(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005527"(macrolide binding)|go:"GO:0005528"(FK506 binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0014802"(terminal cisterna)|go:"GO:0016020"(membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030018"(Z disc)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031312"(extrinsic component of organelle membrane)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032925"(regulation of activin receptor signaling pathway)|go:"GO:0034713"(type I transforming growth factor beta receptor binding)|go:"GO:0042026"(protein refolding)|go:"GO:0042110"(T cell activation)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046332"(SMAD binding)|go:"GO:0048185"(activin binding)|go:"GO:0050776"(regulation of immune response)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:1902991"(regulation of amyloid precursor protein catabolic process)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990425"(ryanodine receptor complex)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|rcsb pdb:1A7X|rcsb pdb:1B6C|rcsb pdb:1BKF|rcsb pdb:1BL4|rcsb pdb:1D6O|rcsb pdb:1D7H|rcsb pdb:1D7I|rcsb pdb:1D7J|rcsb pdb:1EYM|rcsb pdb:1F40|rcsb pdb:1FAP|rcsb pdb:1FKB|rcsb pdb:1FKD|rcsb pdb:1FKF|rcsb pdb:1FKG|rcsb pdb:1FKH|rcsb pdb:1FKI|rcsb pdb:2DG4|rcsb pdb:2DG9|rcsb pdb:2FAP|rcsb pdb:2FKE|rcsb pdb:2ND5|rcsb pdb:2PPN|rcsb pdb:2PPO|rcsb pdb:2PPP|rcsb pdb:2RSE|rcsb pdb:3FAP|rcsb pdb:1FKJ|rcsb pdb:3H9R|rcsb pdb:3MDY|rcsb pdb:4DH0|rcsb pdb:4FAP|rcsb pdb:1FKR|rcsb pdb:4IPX|rcsb pdb:4N19|rcsb pdb:4ODP|rcsb pdb:4ODQ|rcsb pdb:4ODR|rcsb pdb:5I7P|rcsb pdb:5I7Q|rcsb pdb:6I1S|rcsb pdb:1FKS|rcsb pdb:6M4U|rcsb pdb:6OQA|rcsb pdb:6VCU|rcsb pdb:6YF0|rcsb pdb:6YF1|rcsb pdb:6YF2|rcsb pdb:6YF3|reactome:R-HSA-166208|rcsb pdb:1FKT|reactome:R-HSA-2025928|reactome:R-HSA-2173789|reactome:R-HSA-2173791|reactome:R-HSA-3656535|rcsb pdb:1J4H|rcsb pdb:1J4I|reactome:R-HSA-9679191|rcsb pdb:1J4R|rcsb pdb:1NSG|rcsb pdb:1QPF|rcsb pdb:1QPL|rcsb pdb:2DG3|refseq:NP_000792.1|refseq:NP_463460.1|dip:DIP-29710N - inchi key:QFJCIRLUMZQUOT-HPLJOQBZSA-N - figure legend:4|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/02/07 2014/10/16 - rogid:3eikHNIIVs8AFM7PYVWurI/9KUY9606 intact-crc:EC7D6EFF034BB054 false - tag:?-? - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation)