#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P14075 uniprotkb:Q9H1Q7 intact:EBI-9675533|uniprotkb:Q77YG4 intact:EBI-748452|uniprotkb:Q5JUA5|uniprotkb:Q5JUA6|uniprotkb:Q6PK19|uniprotkb:Q86WF5|uniprotkb:Q96CG7|uniprotkb:Q9H1Q6|uniprotkb:Q9H6D1|ensembl:ENSP00000353868 psi-mi:env_htl1c(display_long)|uniprotkb:env(gene name)|psi-mi:env(display_short)|uniprotkb:Env polyprotein(gene name synonym) psi-mi:ped1a_human(display_long)|uniprotkb:PCED1A(gene name)|psi-mi:PCED1A(display_short)|uniprotkb:C20orf81(gene name synonym)|uniprotkb:FAM113A(gene name synonym)|uniprotkb:Protein FAM113A(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-23(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675530|imex:IM-22977-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018154|refseq:NP_057865.1|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0055036"(virion membrane) refseq:NP_073597.2|refseq:NP_001258097.1|refseq:XP_005260861.1|refseq:XP_005260862.1|ensembl:ENSG00000132635(gene)|ensembl:ENST00000360652(transcript)|interpro:IPR026057|mint:Q9H1Q7 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:QMX2JJtovlfFJqzVbOdRDHnLTgQ11927 rogid:L1RRthUFVoaARhQE6LnQV1QLqLk9606 intact-crc:7B6E7EB480CEFAE1|rigid:mKrFoBssKUwQwa7qXzhiZ7ilwc0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14075 uniprotkb:Q9Y3Q8 intact:EBI-9675533|uniprotkb:Q77YG4 intact:EBI-739485|uniprotkb:A8MWR6|ensembl:ENSP00000300181|uniprotkb:A4D2C3|uniprotkb:D6W5V9 psi-mi:env_htl1c(display_long)|uniprotkb:env(gene name)|psi-mi:env(display_short)|uniprotkb:Env polyprotein(gene name synonym) psi-mi:t22d4_human(display_long)|uniprotkb:TSC22D4(gene name)|psi-mi:TSC22D4(display_short)|uniprotkb:TILZ2(gene name synonym)|uniprotkb:TSC22-related-inducible leucine zipper protein 2(gene name synonym)|uniprotkb:Tsc-22-like protein THG-1(gene name synonym)|uniprotkb:THG1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675537|imex:IM-22977-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018154|refseq:NP_057865.1|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0055036"(virion membrane) ensembl:ENSG00000166925(gene)|ensembl:ENST00000300181(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006970"(response to osmotic stress)|interpro:IPR000580(TSC-22 / Dip / Bun)|interpro:IPR042553|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_112197.1|refseq:NP_001289972.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:QMX2JJtovlfFJqzVbOdRDHnLTgQ11927 rogid:eL12cHY76zEPOXzT1HFKPSckS8Y9606 intact-crc:FE6C41ED60906FBB|rigid:B3rb3smPGmDI+EotSgjayUxhJ/I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q2Q067 uniprotkb:Q13015 intact:EBI-9675545 intact:EBI-6269719|ensembl:ENSP00000357917 psi-mi:q2q067_9dela(display_long)|uniprotkb:HBZ(gene name)|psi-mi:HBZ(display_short) psi-mi:af1q_human(display_long)|uniprotkb:MLLT11(gene name)|psi-mi:MLLT11(display_short)|uniprotkb:AF1Q(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11908(humt-)|taxid:11908(Human T-lymphotropic virus 1) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675551|imex:IM-22977-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6DNQ|interpro:IPR026220|go:"GO:0016032"(viral process) ensembl:ENSG00000213190(gene)|ensembl:ENST00000368921(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR026778|interpro:IPR033461|mint:Q13015|refseq:NP_006809.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:j9b0X2J4Nu0iW1SeHJj8GlrL3IE11908 rogid:23mnJAG1OcDgM7eT2rTi1Gv0ZgA9606 intact-crc:0C7904073D95E6AA|rigid:dTWVRZzUodcD/NE2txop73gyvEY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q2Q067 uniprotkb:Q15287 intact:EBI-9675545 intact:EBI-395959|uniprotkb:A8K1P0|uniprotkb:B4DDU8|uniprotkb:B4DZU7|uniprotkb:B7ZA17|uniprotkb:O75308|uniprotkb:Q32P25|uniprotkb:Q8WY42|uniprotkb:Q9NYG3|ensembl:ENSP00000301730|ensembl:ENSP00000315859|ensembl:ENSP00000380275|ensembl:ENSP00000457723|ensembl:ENSP00000457820 psi-mi:q2q067_9dela(display_long)|uniprotkb:HBZ(gene name)|psi-mi:HBZ(display_short) psi-mi:rnps1_human(display_long)|uniprotkb:SR-related protein LDC2(gene name synonym)|uniprotkb:RNPS1(gene name)|psi-mi:RNPS1(display_short)|uniprotkb:LDC2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11908(humt-)|taxid:11908(Human T-lymphotropic virus 1) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675542|imex:IM-22977-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6DNQ|interpro:IPR026220|go:"GO:0016032"(viral process) refseq:NP_006702.1|refseq:NP_542161.1|refseq:NP_001273554.1|refseq:NP_001273555.1|refseq:NP_001273556.1|ensembl:ENSG00000205937(gene)|ensembl:ENST00000301730(transcript)|ensembl:ENST00000320225(transcript)|ensembl:ENST00000397086(transcript)|ensembl:ENST00000565678(transcript)|ensembl:ENST00000568631(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0061574"(ASAP complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034201|interpro:IPR035979|mint:Q15287|rcsb pdb:4A8X|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-9010553|reactome:R-HSA-975957|refseq:XP_005255105.1|refseq:XP_005255106.1|refseq:XP_016878363.1|dip:DIP-32943N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:j9b0X2J4Nu0iW1SeHJj8GlrL3IE11908 rogid:nANu/nh/pD/F6dYE2Sa28OegPGs9606 intact-crc:7475A88CB4A451E4|rigid:b7IxA2EbkcyvNChamphjTr0AjQE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q2Q067 uniprotkb:O95251 intact:EBI-9675545 intact:EBI-473199|uniprotkb:B3KN74|uniprotkb:B4DFB4|uniprotkb:B4DFE0|uniprotkb:B4DF85|uniprotkb:B4DGY4|uniprotkb:E7ER15|uniprotkb:G5E9K7|intact:EBI-10986821|ensembl:ENSP00000259021 psi-mi:q2q067_9dela(display_long)|uniprotkb:HBZ(gene name)|psi-mi:HBZ(display_short) psi-mi:kat7_human(display_long)|uniprotkb:KAT7(gene name)|psi-mi:KAT7(display_short)|uniprotkb:HBO1(gene name synonym)|uniprotkb:HBOa(gene name synonym)|uniprotkb:MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2(gene name synonym)|uniprotkb:Histone acetyltransferase binding to ORC1(gene name synonym)|uniprotkb:MYST2(gene name synonym)|uniprotkb:Lysine acetyltransferase 7(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11908(humt-)|taxid:11908(Human T-lymphotropic virus 1) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675556|imex:IM-22977-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6DNQ|interpro:IPR026220|go:"GO:0016032"(viral process) refseq:NP_001186084.1|refseq:NP_001186085.1|refseq:NP_001186086.1|refseq:NP_001186087.1|refseq:NP_008998.1|dip:DIP-29697N|ensembl:ENSG00000136504(gene)|ensembl:ENST00000259021(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031098"(stress-activated protein kinase signaling cascade)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0036409"(histone H3-K14 acetyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0072708"(response to sorbitol)|go:"GO:0072710"(response to hydroxyurea)|go:"GO:0072716"(response to actinomycin D)|go:"GO:0072720"(response to dithiothreitol)|go:"GO:0072739"(response to anisomycin)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:0090734"(site of DNA damage)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902035"(positive regulation of hematopoietic stem cell proliferation)|go:"GO:2000819"(regulation of nucleotide-excision repair)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR002717(MOZ/SAS-like protein)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR036060|interpro:IPR036388|interpro:IPR040706|mint:O95251|rcsb pdb:5GK9|rcsb pdb:6MAJ|rcsb pdb:6MAK|reactome:R-HSA-3214847 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:j9b0X2J4Nu0iW1SeHJj8GlrL3IE11908 rogid:K27pgvPEe1/+rZXYUkPfMY7PZMs9606 intact-crc:0B54B18759A78F9A|rigid:7DdFZCqzKV+fETi0a7eODFXuIgs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q2Q067 uniprotkb:P32243 intact:EBI-9675545 intact:EBI-954480|uniprotkb:Q6GTV3|uniprotkb:Q9HAW3|uniprotkb:B2RAN5|uniprotkb:Q9P2R1|ensembl:ENSP00000343819|ensembl:ENSP00000386185|ensembl:ENSP00000452336|ensembl:ENSP00000500061 psi-mi:q2q067_9dela(display_long)|uniprotkb:HBZ(gene name)|psi-mi:HBZ(display_short) psi-mi:otx2_human(display_long)|uniprotkb:Orthodenticle homolog 2(gene name synonym)|uniprotkb:OTX2(gene name)|psi-mi:OTX2(display_short) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11908(humt-)|taxid:11908(Human T-lymphotropic virus 1) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675571|imex:IM-22977-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6DNQ|interpro:IPR026220|go:"GO:0016032"(viral process) refseq:NP_068374.1|refseq:NP_758840.1|refseq:NP_001257452.1|refseq:NP_001257453.1|refseq:NP_001257454.1|ensembl:ENSG00000165588(gene)|ensembl:ENST00000339475(transcript)|ensembl:ENST00000408990(transcript)|ensembl:ENST00000555006(transcript)|ensembl:ENST00000673035(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007411"(axon guidance)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0030426"(growth cone)|go:"GO:0030900"(forebrain development)|go:"GO:0030901"(midbrain development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0040036"(regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0090009"(primitive streak formation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000543"(positive regulation of gastrulation)|interpro:IPR001356(Homeobox)|interpro:IPR003022(Transcription factor Otx2)|interpro:IPR003025(Transcription factor Otx)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:j9b0X2J4Nu0iW1SeHJj8GlrL3IE11908 rogid:ceYynldw4n+AnFOVi5L0PONYj609606 intact-crc:57C81ED72E2C7113|rigid:9HKjcGKrnbQsUIHtBlVMjmBJj70 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q2Q067 uniprotkb:P31249 intact:EBI-9675545 intact:EBI-3957655|ensembl:ENSP00000249440|ensembl:ENSP00000386498|ensembl:ENSP00000507129|uniprotkb:Q99955|uniprotkb:Q9BSC5 psi-mi:q2q067_9dela(display_long)|uniprotkb:HBZ(gene name)|psi-mi:HBZ(display_short) psi-mi:hxd3_human(display_long)|uniprotkb:HOXD3(gene name)|psi-mi:HOXD3(display_short)|uniprotkb:HOX1D(gene name synonym)|uniprotkb:HOX4A(gene name synonym)|uniprotkb:Homeobox protein Hox-4A(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11908(humt-)|taxid:11908(Human T-lymphotropic virus 1) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675566|imex:IM-22977-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6DNQ|interpro:IPR026220|go:"GO:0016032"(viral process) ensembl:ENSG00000128652(gene)|ensembl:ENST00000249440(transcript)|ensembl:ENST00000410016(transcript)|ensembl:ENST00000683222(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016235"(aggresome)|go:"GO:0016604"(nuclear body)|go:"GO:0030878"(thyroid gland development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051216"(cartilage development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR025281|reactome:R-HSA-5617472|refseq:XP_011509367.1|refseq:XP_011509368.1|refseq:NP_008829.3|refseq:XP_005246566.1|refseq:XP_005246567.1|refseq:XP_005246568.1|refseq:XP_005246570.1|refseq:XP_006712540.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:j9b0X2J4Nu0iW1SeHJj8GlrL3IE11908 rogid:6egSlcCWXDnEWbOnwNGI/0ZxBM49606 intact-crc:57CB331D2EA1D213|rigid:xDboQUlGrEHbADgxPl8tFHEDGPA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q2Q067 uniprotkb:P02794 intact:EBI-9675545 intact:EBI-713259|uniprotkb:Q3KRA8|uniprotkb:Q3SWW1|ensembl:ENSP00000273550|ensembl:ENSP00000484477|uniprotkb:B3KNR5 psi-mi:q2q067_9dela(display_long)|uniprotkb:HBZ(gene name)|psi-mi:HBZ(display_short) psi-mi:frih_human(display_long)|uniprotkb:Cell proliferation-inducing gene 15 protein(gene name synonym)|uniprotkb:FTH1(gene name)|psi-mi:FTH1(display_short)|uniprotkb:FTH(gene name synonym)|uniprotkb:FTHL6(gene name synonym)|uniprotkb:PIG15(orf name)|uniprotkb:OK/SW-cl.84(orf name) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11908(humt-)|taxid:11908(Human T-lymphotropic virus 1) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675561|imex:IM-22977-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6DNQ|interpro:IPR026220|go:"GO:0016032"(viral process) refseq:NP_002023.2|ensembl:ENSG00000167996(gene)|ensembl:ENST00000273550(transcript)|ensembl:ENST00000620041(transcript)|go:"GO:0004322"(ferroxidase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006880"(intracellular sequestering of iron ion)|go:"GO:0006955"(immune response)|go:"GO:0008043"(intracellular ferritin complex)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008199"(ferric iron binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0044754"(autolysosome)|mint:P02794|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:1FHA|rcsb pdb:2CEI|rcsb pdb:2CHI|rcsb pdb:2CIH|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001519(Ferritin, N-terminal)|interpro:IPR008331(Ferritin and Dps)|interpro:IPR009040(Ferritin-like)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR012347(Ferritin-related)|interpro:IPR014034(Ferritin, conserved site)|rcsb pdb:2CLU|rcsb pdb:2CN6|rcsb pdb:2CN7|rcsb pdb:2FHA|rcsb pdb:2IU2|rcsb pdb:2Z6M|rcsb pdb:3AJO|rcsb pdb:3AJP|rcsb pdb:3AJQ|rcsb pdb:3ERZ|rcsb pdb:3ES3|rcsb pdb:4DYX|rcsb pdb:4DYY|rcsb pdb:4DYZ|rcsb pdb:4Y08|rcsb pdb:4YKH|rcsb pdb:4ZJK|rcsb pdb:5CMQ|rcsb pdb:5CMR|rcsb pdb:5GN8|rcsb pdb:5GOU|rcsb pdb:5JKK|rcsb pdb:5JKL|rcsb pdb:5JKM|rcsb pdb:5N26|rcsb pdb:5N27|rcsb pdb:5UP7|rcsb pdb:5UP8|rcsb pdb:5UP9|rcsb pdb:5VTD|rcsb pdb:5XB1|rcsb pdb:5YI5|rcsb pdb:5ZND|rcsb pdb:6B8F|rcsb pdb:6B8G|rcsb pdb:4DZ0|rcsb pdb:6FTV|rcsb pdb:6GSR|rcsb pdb:6H5I|rcsb pdb:6H6T|rcsb pdb:6H6U|rcsb pdb:6IPC|rcsb pdb:6IPO|rcsb pdb:6IPP|rcsb pdb:6IPQ|rcsb pdb:6J4A|rcsb pdb:6J7G|rcsb pdb:6JOB|rcsb pdb:6JPS|rcsb pdb:6KE2|rcsb pdb:6KE4|rcsb pdb:4OYN|rcsb pdb:6M52|rcsb pdb:6M54|rcsb pdb:6WYF|rcsb pdb:6WYG|rcsb pdb:6WYH|rcsb pdb:6Z6U|rcsb pdb:6Z9E|rcsb pdb:6Z9F|rcsb pdb:7A6A|rcsb pdb:7A6B|rcsb pdb:7CK8|rcsb pdb:7CK9|rcsb pdb:7JGK|rcsb pdb:7JGL|rcsb pdb:7JGM|rcsb pdb:7JGN|rcsb pdb:7JGO|rcsb pdb:7JGP|rcsb pdb:7JGQ|rcsb pdb:7K26|rcsb pdb:7K3V|rcsb pdb:7K3W|reactome:R-HSA-3000480|reactome:R-HSA-432722|reactome:R-HSA-6798695|reactome:R-HSA-917937|dip:DIP-38301N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:j9b0X2J4Nu0iW1SeHJj8GlrL3IE11908 rogid:TchHgRpv+inA8BQ5i0OHaa267tQ9606 intact-crc:57C97CBC55C9FCB0|rigid:VYNMsot3bR90yEWhV8bCJBDq9y0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q2Q067 uniprotkb:Q15365 intact:EBI-9675545 intact:EBI-946095|uniprotkb:Q13157|uniprotkb:Q14975|ensembl:ENSP00000305556 psi-mi:q2q067_9dela(display_long)|uniprotkb:HBZ(gene name)|psi-mi:HBZ(display_short) psi-mi:pcbp1_human(display_long)|uniprotkb:PCBP1(gene name)|psi-mi:PCBP1(display_short)|uniprotkb:Alpha-CP1(gene name synonym)|uniprotkb:Nucleic acid-binding protein SUB2.3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11908(humt-)|taxid:11908(Human T-lymphotropic virus 1) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675576|imex:IM-22977-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6DNQ|interpro:IPR026220|go:"GO:0016032"(viral process) refseq:NP_006187.2|dip:DIP-38136N|ensembl:ENSG00000169564(gene)|ensembl:ENST00000303577(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098847"(sequence-specific single stranded DNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15365|rcsb pdb:1WVN|rcsb pdb:1ZTG|rcsb pdb:3VKE|reactome:R-HSA-72163|reactome:R-HSA-72203 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:j9b0X2J4Nu0iW1SeHJj8GlrL3IE11908 rogid:x72fawo4plQ+ipfqIoREIDHc2bA9606 intact-crc:74755C8E81C551E4|rigid:QfbjiTWvFxGWmySHh6WpWP4NvfI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q2Q067 uniprotkb:Q9UH92 intact:EBI-9675545 intact:EBI-741109|intact:EBI-28976799|ensembl:ENSP00000246912|uniprotkb:Q53XM6|uniprotkb:Q96FL2|uniprotkb:Q9H2V0|uniprotkb:Q9H2V1|uniprotkb:Q9H2V2|uniprotkb:Q9NXN3|uniprotkb:B2RAV8|uniprotkb:A8K2J3|uniprotkb:B2RD73 psi-mi:q2q067_9dela(display_long)|uniprotkb:HBZ(gene name)|psi-mi:HBZ(display_short) psi-mi:mlx_human(display_long)|uniprotkb:Max-like bHLHZip protein(gene name synonym)|uniprotkb:BHLHD13(gene name synonym)|uniprotkb:Protein BigMax(gene name synonym)|uniprotkb:Transcription factor-like protein 4(gene name synonym)|uniprotkb:MLX(gene name)|psi-mi:MLX(display_short)|uniprotkb:TCFL4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 13(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11908(humt-)|taxid:11908(Human T-lymphotropic virus 1) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675586|imex:IM-22977-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6DNQ|interpro:IPR026220|go:"GO:0016032"(viral process) refseq:NP_733752.1|refseq:NP_937847.1|refseq:NP_937848.1|ensembl:ENSG00000108788(gene)|ensembl:ENST00000246912(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR032647|interpro:IPR036638|reactome:R-HSA-163765|go:"GO:0005654"(nucleoplasm)|ensembl:ENSP00000246912|ensembl:ENST00000346833|ensembl:ENSP00000320913|ensembl:ENST00000435881|ensembl:ENSP00000416627 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:j9b0X2J4Nu0iW1SeHJj8GlrL3IE11908 rogid:5zIr/dC+5Gre7BiEy/8g0MEdppY9606 intact-crc:F6696509E8DD15B9|rigid:qa+eFixyWgLr29JX/uHLc0Sjnik false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q2Q067 uniprotkb:Q9HD26 intact:EBI-9675545 intact:EBI-349832|uniprotkb:A6NM30|uniprotkb:Q59FS4|uniprotkb:Q969U8|ensembl:ENSP00000357484 psi-mi:q2q067_9dela(display_long)|uniprotkb:HBZ(gene name)|psi-mi:HBZ(display_short) psi-mi:gopc_human(display_long)|uniprotkb:CAL(gene name synonym)|uniprotkb:FIG(gene name synonym)|uniprotkb:GOPC(gene name)|psi-mi:GOPC(display_short)|uniprotkb:PDZ protein interacting specifically with TC10(gene name synonym)|uniprotkb:CFTR-associated ligand(gene name synonym)|uniprotkb:Fused in glioblastoma(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11908(humt-)|taxid:11908(Human T-lymphotropic virus 1) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675581|imex:IM-22977-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6DNQ|interpro:IPR026220|go:"GO:0016032"(viral process) refseq:NP_001017408.1|refseq:NP_065132.1|go:"GO:0043004"(cytoplasmic sequestering of CFTR protein)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045176"(apical protein localization)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR038879|mint:Q9HD26|rcsb pdb:2DC2|rcsb pdb:2LOB|rcsb pdb:4E34|rcsb pdb:4E35|rcsb pdb:4JOE|rcsb pdb:4JOF|rcsb pdb:4JOG|rcsb pdb:4JOH|rcsb pdb:4JOJ|rcsb pdb:4JOK|rcsb pdb:4JOP|rcsb pdb:4JOR|rcsb pdb:4K6Y|rcsb pdb:4K72|rcsb pdb:4K75|rcsb pdb:4K76|rcsb pdb:4K78|rcsb pdb:4NMO|rcsb pdb:4NMP|rcsb pdb:4NMQ|rcsb pdb:4NMR|rcsb pdb:4NMS|rcsb pdb:4NMT|go:"GO:0042802"(identical protein binding)|rcsb pdb:4NMV|rcsb pdb:4Q6H|rcsb pdb:4Q6S|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6OV7|rcsb pdb:6V84|rcsb pdb:6XNJ|reactome:R-HSA-5627083|reactome:R-HSA-9013406|ensembl:ENSG00000047932(gene)|ensembl:ENST00000368498(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0010360"(negative regulation of anion channel activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030425"(dendrite)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0032991"(protein-containing complex) psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:j9b0X2J4Nu0iW1SeHJj8GlrL3IE11908 rogid:bXzu5wvJifZwB+Q52cgC4tZQl/k9606 intact-crc:7078347BB2092720|rigid:hWgX/hgFqbIsPKT0U437nmr2u40 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q2Q067 uniprotkb:Q15038 intact:EBI-9675545 intact:EBI-724310|ensembl:ENSP00000394699|uniprotkb:E9PB45|uniprotkb:A8K254|uniprotkb:B4DDT5|uniprotkb:C9JA96|uniprotkb:C9JP84|uniprotkb:B4E1G3|uniprotkb:F8VU62 psi-mi:q2q067_9dela(display_long)|uniprotkb:HBZ(gene name)|psi-mi:HBZ(display_short) psi-mi:dazp2_human(display_long)|uniprotkb:Deleted in azoospermia-associated protein 2(gene name synonym)|uniprotkb:DAZAP2(gene name)|psi-mi:DAZAP2(display_short)|uniprotkb:KIAA0058(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11908(humt-)|taxid:11908(Human T-lymphotropic virus 1) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675591|imex:IM-22977-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6DNQ|interpro:IPR026220|go:"GO:0016032"(viral process) ensembl:ENSG00000183283(gene)|ensembl:ENST00000412716(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050699"(WW domain binding)|interpro:IPR022730|mint:Q15038|refseq:NP_001129736.1|refseq:NP_055579.1|ensembl:ENSP00000394699|ensembl:ENST00000425012|ensembl:ENSP00000408251|ensembl:ENST00000439799|ensembl:ENSP00000398804|ensembl:ENST00000449723|ensembl:ENSP00000412812|ensembl:ENST00000549555|ensembl:ENSP00000448051|ensembl:ENST00000549732|ensembl:ENSP00000446554|refseq:NP_001129741.1|refseq:NP_001129739.1|refseq:NP_001129740.1|refseq:NP_001129738.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:j9b0X2J4Nu0iW1SeHJj8GlrL3IE11908 rogid:ASRqCZBG4q1U/y95PUSMKsgfm/g9606 intact-crc:0C7B491CFE8EA0AA|rigid:k4XC3Bxm8qxHmMtz4Sq5gJdyg1g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C206 uniprotkb:Q96R06 intact:EBI-9675596|uniprotkb:O56230 intact:EBI-413317|uniprotkb:O95213|uniprotkb:Q9BWE8|uniprotkb:Q9NT17|uniprotkb:Q9UFE6|intact:EBI-28972684|ensembl:ENSP00000323300 psi-mi:rex_htl1c(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-1(gene name synonym)|uniprotkb:p27Rex(gene name synonym) psi-mi:spag5_human(display_long)|uniprotkb:SPAG5(gene name)|psi-mi:SPAG5(display_short)|uniprotkb:Astrin(gene name synonym)|uniprotkb:Mitotic spindle-associated protein p126(gene name synonym)|uniprotkb:Deepest(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675598|imex:IM-22977-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1EXY|refseq:NP_057863.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) refseq:NP_006452.3|ensembl:ENSP00000323300|ensembl:ENSG00000076382(gene)|ensembl:ENST00000321765(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007051"(spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0016604"(nuclear body)|go:"GO:0030496"(midbody)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0036064"(ciliary basal body)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0051301"(cell division)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR028728|mint:Q96R06|dip:DIP-30998N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:Jg3y2XqUP/JBerfBYcxMesTuQFQ11927 rogid:WOMksaINKpqSxqeGIzbmcSRcgdw9606 intact-crc:5556F435A2E51EC5|rigid:GZPtivvl1EWB/yUq46LpaLg7z2k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C206 uniprotkb:O43186 intact:EBI-9675596|uniprotkb:O56230 intact:EBI-748171|uniprotkb:Q0QD45|ensembl:ENSP00000221996|ensembl:ENSP00000445565 psi-mi:rex_htl1c(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-1(gene name synonym)|uniprotkb:p27Rex(gene name synonym) psi-mi:crx_human(display_long)|uniprotkb:CRX(gene name)|psi-mi:CRX(display_short)|uniprotkb:CORD2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675603|imex:IM-22977-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1EXY|refseq:NP_057863.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) refseq:NP_000545.1|ensembl:ENSG00000105392(gene)|ensembl:ENST00000221996(transcript)|ensembl:ENST00000539067(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050896"(response to stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:Jg3y2XqUP/JBerfBYcxMesTuQFQ11927 rogid:v/bkO/0iLzq1Q2HtieWQQ40RF9M9606 intact-crc:F487CE594415476D|rigid:1I6FqAFm29fEgwnuKuim24HT63Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C206 uniprotkb:Q96FJ2 intact:EBI-9675596|uniprotkb:O56230 intact:EBI-742371|uniprotkb:B2R5B4|ensembl:ENSP00000477310 psi-mi:rex_htl1c(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-1(gene name synonym)|uniprotkb:p27Rex(gene name synonym) psi-mi:dyl2_human(display_long)|uniprotkb:DYNLL2(gene name)|psi-mi:DYNLL2(display_short)|uniprotkb:Dynein light chain LC8-type 2(gene name synonym)|uniprotkb:DLC2(gene name synonym)|uniprotkb:8 kDa dynein light chain b(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675608|imex:IM-22977-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1EXY|refseq:NP_057863.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) go:"GO:0005813"(centrosome)|refseq:NP_542408.1|ensembl:ENSG00000264364(gene)|ensembl:ENST00000579991(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0007017"(microtubule-based process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0030286"(dynein complex)|go:"GO:0031475"(myosin V complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097542"(ciliary tip)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:Q96FJ2|rcsb pdb:2XQQ|rcsb pdb:3P8M|rcsb pdb:4D07|reactome:R-HSA-139910|reactome:R-HSA-141444|reactome:R-HSA-1632852|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-5620924|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:Jg3y2XqUP/JBerfBYcxMesTuQFQ11927 rogid:4RFpJF40RBja5mOvt/aCv3miiDU9606 intact-crc:970FD050C9F6392C|rigid:Nh0EMng3CiDDBeEjvC43fAW+OyU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C206 uniprotkb:Q9H4K1 intact:EBI-9675596|uniprotkb:O56230 intact:EBI-740128|uniprotkb:Q6ICD0|uniprotkb:Q9Y413|ensembl:ENSP00000483356|uniprotkb:A0A087X0F7 psi-mi:rex_htl1c(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-1(gene name synonym)|uniprotkb:p27Rex(gene name synonym) psi-mi:ribc2_human(display_long)|uniprotkb:RIBC2(gene name)|psi-mi:RIBC2(display_short)|uniprotkb:C22orf11(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675638|imex:IM-22977-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1EXY|refseq:NP_057863.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) ensembl:ENSG00000128408(gene)|ensembl:ENST00000614167(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR008805(RIB43A)|refseq:XP_005261581.1|refseq:NP_056468.3 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2019/11/14 rogid:Jg3y2XqUP/JBerfBYcxMesTuQFQ11927 rogid:rU6ggF8fZGGy7ICGFHxeMZQLkw49606 intact-crc:67C651E837DBC283|rigid:DAO5fJ3tQ4SSM7vG0klip2Rqyqs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C206 uniprotkb:Q6PF05 intact:EBI-9675596|uniprotkb:O56230 intact:EBI-8656864|ensembl:ENSP00000422188|uniprotkb:Q96LJ2|intact:MINT-8163808|uniprotkb:Q6RGS4|uniprotkb:Q8N7R3|uniprotkb:G8IJH6 psi-mi:rex_htl1c(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-1(gene name synonym)|uniprotkb:p27Rex(gene name synonym) psi-mi:tt23l_human(display_long)|uniprotkb:TTC23L(gene name)|psi-mi:TTC23L(display_short) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675613|imex:IM-22977-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1EXY|refseq:NP_057863.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) ensembl:ENSG00000205838(gene)|ensembl:ENST00000505624(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0030496"(midbody)|go:"GO:0034976"(response to endoplasmic reticulum stress)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR042621|mint:Q6PF05|refseq:NP_001304878.1|refseq:NP_653326.3 psi-mi:"MI:0471"(mint) - comment:mint figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:Jg3y2XqUP/JBerfBYcxMesTuQFQ11927 rogid:SRndoUysST7RgIovvs89vd30vMk9606 intact-crc:2AFD588737C73B09|rigid:ZAN3rdneLPDamL9kMFNrIq2H8bs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C206 uniprotkb:O14641 intact:EBI-9675596|uniprotkb:O56230 intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3 psi-mi:rex_htl1c(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-1(gene name synonym)|uniprotkb:p27Rex(gene name synonym) psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675618|imex:IM-22977-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1EXY|refseq:NP_057863.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:Jg3y2XqUP/JBerfBYcxMesTuQFQ11927 rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606 intact-crc:F486AC49A953F688|rigid:5+hz7SScxJR48jHh6c3fpIGSdgM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C206 uniprotkb:Q8N448 intact:EBI-9675596|uniprotkb:O56230 intact:EBI-2340947|uniprotkb:Q6ZMH2|uniprotkb:Q5W0P0|uniprotkb:Q96SH4|ensembl:ENSP00000325929|ensembl:ENSP00000497224 psi-mi:rex_htl1c(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-1(gene name synonym)|uniprotkb:p27Rex(gene name synonym) psi-mi:lnx2_human(display_long)|uniprotkb:LNX2(gene name)|psi-mi:LNX2(display_short)|uniprotkb:PDZRN1(gene name synonym)|uniprotkb:Numb-binding protein 2(gene name synonym)|uniprotkb:PDZ domain-containing RING finger protein 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675623|imex:IM-22977-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1EXY|refseq:NP_057863.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) refseq:NP_699202.1|refseq:XP_016875923.1|ensembl:ENSG00000139517(gene)|ensembl:ENST00000316334(transcript)|ensembl:ENST00000649248(transcript)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036034|mint:Q8N448|rcsb pdb:2VWR|rcsb pdb:5DIN|rcsb pdb:5E11|rcsb pdb:5E1Y|rcsb pdb:5E21|rcsb pdb:5E22 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:Jg3y2XqUP/JBerfBYcxMesTuQFQ11927 rogid:cIS5t4XkbnIgelDlUc692nI285g9606 intact-crc:ED3C558A41F01271|rigid:75b2LoQRYcBqemSLaxTZkX5CZX4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C206 uniprotkb:Q8N448 intact:EBI-9675596|uniprotkb:O56230 intact:EBI-2340947|uniprotkb:Q6ZMH2|uniprotkb:Q5W0P0|uniprotkb:Q96SH4|ensembl:ENSP00000325929|ensembl:ENSP00000497224 psi-mi:rex_htl1c(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-1(gene name synonym)|uniprotkb:p27Rex(gene name synonym) psi-mi:lnx2_human(display_long)|uniprotkb:LNX2(gene name)|psi-mi:LNX2(display_short)|uniprotkb:PDZRN1(gene name synonym)|uniprotkb:Numb-binding protein 2(gene name synonym)|uniprotkb:PDZ domain-containing RING finger protein 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675628|imex:IM-22977-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1EXY|refseq:NP_057863.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) refseq:NP_699202.1|refseq:XP_016875923.1|ensembl:ENSG00000139517(gene)|ensembl:ENST00000316334(transcript)|ensembl:ENST00000649248(transcript)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036034|mint:Q8N448|rcsb pdb:2VWR|rcsb pdb:5DIN|rcsb pdb:5E11|rcsb pdb:5E1Y|rcsb pdb:5E21|rcsb pdb:5E22 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:Jg3y2XqUP/JBerfBYcxMesTuQFQ11927 rogid:cIS5t4XkbnIgelDlUc692nI285g9606 intact-crc:95300C635618E33F|rigid:75b2LoQRYcBqemSLaxTZkX5CZX4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C206 uniprotkb:P37198 intact:EBI-9675596|uniprotkb:O56230 intact:EBI-347978|intact:EBI-28983799|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|uniprotkb:Q6GTM2|uniprotkb:Q503A4|uniprotkb:Q96C43|uniprotkb:Q9NSL1|uniprotkb:B3KWU5 psi-mi:rex_htl1c(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-1(gene name synonym)|uniprotkb:p27Rex(gene name synonym) psi-mi:nup62_human(display_long)|uniprotkb:NUP62(gene name)|psi-mi:NUP62(display_short)|uniprotkb:62 kDa nucleoporin(gene name synonym)|uniprotkb:Nucleoporin Nup62(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675633|imex:IM-22977-20 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1EXY|refseq:NP_057863.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) refseq:NP_714941.1|ensembl:ENSG00000213024(gene)|ensembl:ENST00000352066(transcript)|ensembl:ENST00000422090(transcript)|ensembl:ENST00000596217(transcript)|ensembl:ENST00000597029(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007569"(cell aging)|go:"GO:0008219"(cell death)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0003682"(chromatin binding)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0051028"(mRNA transport)|go:"GO:0051425"(PTB domain binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072686"(mitotic spindle)|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|go:"GO:0090543"(Flemming body)|go:"GO:0098534"(centriole assembly)|go:"GO:1903438"(positive regulation of mitotic cytokinetic process)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007758(Nucleoporin, Nsp1-like, C-terminal)|interpro:IPR026010|interpro:IPR033072|mint:P37198|rcsb pdb:2H4D|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|refseq:NP_714940.1|refseq:NP_001180286.1|refseq:NP_036478.2|refseq:NP_057637.2|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|dip:DIP-29749N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:Jg3y2XqUP/JBerfBYcxMesTuQFQ11927 rogid:v7mvKvTtVEnLMwcpUZIcdAzge009606 intact-crc:A92744F6E5454129|rigid:4FMEsLx4zgQj7SHGCI1f9JblGzs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C206 uniprotkb:Q9GZT8 intact:EBI-9675596|uniprotkb:O56230 intact:EBI-740897|uniprotkb:Q9H2D2|uniprotkb:Q9HC18|uniprotkb:Q6X735|uniprotkb:Q53TX4|ensembl:ENSP00000386394|ensembl:ENSP00000387315|ensembl:ENSP00000498853 psi-mi:rex_htl1c(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-1(gene name synonym)|uniprotkb:p27Rex(gene name synonym) psi-mi:nif3l_human(display_long)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein(gene name synonym)|uniprotkb:MDS015(orf name)|uniprotkb:My018(orf name)|uniprotkb:NIF3L1(gene name)|psi-mi:NIF3L1(display_short)|uniprotkb:ALS2CR1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675658|imex:IM-22977-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1EXY|refseq:NP_057863.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) refseq:NP_001129511.1|refseq:NP_001135827.1|refseq:NP_068596.2|refseq:XP_011509887.1|refseq:XP_011509884.1|refseq:XP_011509885.1|refseq:XP_011509886.1|refseq:NP_001135828.1|refseq:XP_005246799.1|refseq:XP_016860119.1|ensembl:ENSG00000196290(gene)|ensembl:ENST00000409020(transcript)|ensembl:ENST00000409357(transcript)|ensembl:ENST00000651500(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1903507"(negative regulation of nucleic acid-templated transcription)|interpro:IPR002678(NGG1p interacting factor 3, NIF3)|interpro:IPR017222(Uncharacterised conserved protein UCP037490, NIF3, eukaryota)|interpro:IPR036069|mint:Q9GZT8 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:Jg3y2XqUP/JBerfBYcxMesTuQFQ11927 rogid:Vvyb7CJpcwGtGAVKT2Zoqycr2yQ9606 intact-crc:F3E4F4EF9A4079DD|rigid:4NMGGQW91m+i2YQg0k5ZtqLL550 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C206 uniprotkb:Q53EZ4 intact:EBI-9675596|uniprotkb:O56230 intact:EBI-747776|uniprotkb:Q32WF5|uniprotkb:Q3MV20|uniprotkb:Q5VY28|uniprotkb:Q6N034|ensembl:ENSP00000360540|uniprotkb:Q96H32|uniprotkb:Q9NVS7|uniprotkb:B2RDG8|intact:EBI-10173536|uniprotkb:D3DR37|intact:EBI-28973801 psi-mi:rex_htl1c(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-1(gene name synonym)|uniprotkb:p27Rex(gene name synonym) psi-mi:cep55_human(display_long)|uniprotkb:Up-regulated in colon cancer 6(gene name synonym)|uniprotkb:CEP55(gene name)|psi-mi:CEP55(display_short)|uniprotkb:URCC6(gene name synonym)|uniprotkb:C10orf3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675653|imex:IM-22977-24 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1EXY|refseq:NP_057863.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) refseq:NP_001120654.1|refseq:NP_060601.3|ensembl:ENSG00000138180(gene)|ensembl:ENST00000371485(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|mint:Q53EZ4|rcsb pdb:3E1R|rcsb pdb:3WUT|rcsb pdb:3WUU|rcsb pdb:3WUV|go:"GO:0005814"(centriole)|ensembl:ENSP00000360540|dip:DIP-44581N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:Jg3y2XqUP/JBerfBYcxMesTuQFQ11927 rogid:tuo36vVb8ZgPDR81YjZFNEg559w9606 intact-crc:C76B6A56A28B9154|rigid:yhhSNDtugoLmK9/ZM9LQkj2SQag false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C206 uniprotkb:P23497 intact:EBI-9675596|uniprotkb:O56230 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 psi-mi:rex_htl1c(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-1(gene name synonym)|uniprotkb:p27Rex(gene name synonym) psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675663|imex:IM-22977-26 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1EXY|refseq:NP_057863.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:Jg3y2XqUP/JBerfBYcxMesTuQFQ11927 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 intact-crc:4A2D2A73E7C436C9|rigid:UcDjCflEfLDER3KTBmkMsoilAu4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C206 uniprotkb:P63165 intact:EBI-9675596|uniprotkb:O56230 intact:EBI-80140|uniprotkb:P55856|uniprotkb:Q6FGG0|uniprotkb:Q6NZ62|uniprotkb:Q93068|intact:EBI-28970052|ensembl:ENSP00000376076|ensembl:ENSP00000376077|uniprotkb:B2R4I5|uniprotkb:A8MUS8 psi-mi:rex_htl1c(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-1(gene name synonym)|uniprotkb:p27Rex(gene name synonym) psi-mi:sumo1_human(display_long)|uniprotkb:SUMO1(gene name)|psi-mi:SUMO1(display_short)|uniprotkb:Sentrin(gene name synonym)|uniprotkb:Ubiquitin-like protein SMT3C(gene name synonym)|uniprotkb:Ubiquitin-homology domain protein PIC1(gene name synonym)|uniprotkb:Ubiquitin-like protein UBL1(gene name synonym)|uniprotkb:GAP-modifying protein 1(gene name synonym)|uniprotkb:SMT3 homolog 3(gene name synonym)|uniprotkb:SMT3C(gene name synonym)|uniprotkb:SMT3H3(gene name synonym)|uniprotkb:UBL1(gene name synonym)|uniprotkb:OK/SW-cl.43(orf name) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675643|imex:IM-22977-22 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1EXY|refseq:NP_057863.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) refseq:NP_001005781.1|refseq:NP_003343.1|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045759"(negative regulation of action potential)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:0060021"(roof of mouth development)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0097165"(nuclear stress granule)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|mint:P63165|rcsb pdb:1A5R|rcsb pdb:1TGZ|rcsb pdb:1WYW|rcsb pdb:1Y8R|rcsb pdb:1Z5S|rcsb pdb:2ASQ|rcsb pdb:2BF8|rcsb pdb:2G4D|rcsb pdb:2IO2|rcsb pdb:2IY0|rcsb pdb:2IY1|rcsb pdb:2KQS|rcsb pdb:2LAS|rcsb pdb:2MW5|rcsb pdb:2N1A|rcsb pdb:2N1V|rcsb pdb:2PE6|rcsb pdb:2UYZ|rcsb pdb:2VRR|rcsb pdb:3KYC|rcsb pdb:3KYD|rcsb pdb:3RZW|rcsb pdb:3UIP|rcsb pdb:4WJN|rcsb pdb:4WJO|rcsb pdb:4WJP|rcsb pdb:4WJQ|rcsb pdb:5AEK|rcsb pdb:5B7A|rcsb pdb:5ELJ|rcsb pdb:5GHD|rcsb pdb:6EOP|rcsb pdb:6EOT|rcsb pdb:6J4I|rcsb pdb:6JXU|rcsb pdb:6JXV|rcsb pdb:6K5T|rcsb pdb:6TRW|rcsb pdb:6UYO|rcsb pdb:6UYP|rcsb pdb:6UYQ|rcsb pdb:6UYR|rcsb pdb:6UYS|ensembl:ENSG00000116030(gene)|ensembl:ENST00000392245(transcript)|ensembl:ENST00000392246(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010621"(negative regulation of transcription by transcription factor localization)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019899"(enzyme binding)|rcsb pdb:6UYU|rcsb pdb:6UYV|rcsb pdb:6UYX|rcsb pdb:6UYY|rcsb pdb:6UYZ|rcsb pdb:6V7P|rcsb pdb:6V7Q|rcsb pdb:6V7R|rcsb pdb:6UYT|rcsb pdb:6V7S|rcsb pdb:6WW3|rcsb pdb:6XOG|rcsb pdb:6XOH|rcsb pdb:6XOI|reactome:R-HSA-3065676|reactome:R-HSA-3065678|reactome:R-HSA-3065679|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-4551638|reactome:R-HSA-877312|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000392244|ensembl:ENSP00000376075|ensembl:ENSP00000376076|ensembl:ENSP00000376077|refseq:NP_001005782.1|dip:DIP-29080N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:Jg3y2XqUP/JBerfBYcxMesTuQFQ11927 rogid:mflrn+v4fHL8UdmLodfZBZA6eAQ9606 intact-crc:7E6CDB2B866C830D|rigid:t7EF4fKWWh55UZDohaw+Ju+t6Kc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C206 uniprotkb:Q9NZD8 intact:EBI-9675596|uniprotkb:O56230 intact:EBI-742688|uniprotkb:B4DW44|uniprotkb:Q6ZMB6|ensembl:ENSP00000204566|ensembl:ENSP00000404111 psi-mi:rex_htl1c(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-1(gene name synonym)|uniprotkb:p27Rex(gene name synonym) psi-mi:spg21_human(display_long)|uniprotkb:Spastic paraplegia 21 autosomal recessive Mast syndrome protein(gene name synonym)|uniprotkb:Acid cluster protein 33(gene name synonym)|uniprotkb:SPG21(gene name)|psi-mi:SPG21(display_short)|uniprotkb:ACP33(gene name synonym)|uniprotkb:BM-019(orf name)|uniprotkb:GL010(orf name)|uniprotkb:Spastic paraplegia 21 protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675648|imex:IM-22977-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1EXY|refseq:NP_057863.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) refseq:NP_001121361.1|refseq:NP_001121362.1|refseq:NP_057714.1|ensembl:ENSG00000090487(gene)|ensembl:ENST00000204566(transcript)|ensembl:ENST00000433215(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR026151|interpro:IPR029058|mint:Q9NZD8|refseq:XP_005254494.1|refseq:XP_016877786.1|refseq:XP_016877787.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:Jg3y2XqUP/JBerfBYcxMesTuQFQ11927 rogid:MoKySBpEYFNm7Lox/HM5nnkmhkA9606 intact-crc:293A2F8382E454D2|rigid:bgkC4cu3dTUi1zvtGwDBkwzL61c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C206 uniprotkb:O14503 intact:EBI-9675596|uniprotkb:O56230 intact:EBI-711810|uniprotkb:Q96TD3|ensembl:ENSP00000256495 psi-mi:rex_htl1c(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-1(gene name synonym)|uniprotkb:p27Rex(gene name synonym) psi-mi:bhe40_human(display_long)|uniprotkb:BHLHE40(gene name)|psi-mi:BHLHE40(display_short)|uniprotkb:Differentially expressed in chondrocytes protein 1(gene name synonym)|uniprotkb:Enhancer-of-split and hairy-related protein 2(gene name synonym)|uniprotkb:Stimulated by retinoic acid gene 13 protein(gene name synonym)|uniprotkb:BHLHB2(gene name synonym)|uniprotkb:DEC1(gene name synonym)|uniprotkb:SHARP2(gene name synonym)|uniprotkb:STRA13(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675688|imex:IM-22977-31 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1EXY|refseq:NP_057863.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) ensembl:ENSG00000134107(gene)|ensembl:ENST00000256495(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016604"(nuclear body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043426"(MRF binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|refseq:NP_003661.1|dip:DIP-36698N|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:O14503|reactome:R-HSA-1368108 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:Jg3y2XqUP/JBerfBYcxMesTuQFQ11927 rogid:JZrZ1Yo2PF33s9Lf8rLTHCqoptk9606 intact-crc:F4865B66A0F0F688|rigid:ghLwRctQMwqQcdiD+Lnej6Zuh+w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C206 uniprotkb:Q9BRK4 intact:EBI-9675596|uniprotkb:O56230 intact:EBI-741037|ensembl:ENSP00000359240|ensembl:ENSP00000359243|uniprotkb:Q8N3I0|uniprotkb:Q96J79|uniprotkb:Q96JL2|uniprotkb:B1AL14|uniprotkb:D3DR72 psi-mi:rex_htl1c(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-1(gene name synonym)|uniprotkb:p27Rex(gene name synonym) psi-mi:lzts2_human(display_long)|uniprotkb:Protein LAPSER1(gene name synonym)|uniprotkb:LZTS2(gene name)|psi-mi:LZTS2(display_short)|uniprotkb:KIAA1813(gene name synonym)|uniprotkb:LAPSER1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675683|imex:IM-22977-30 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1EXY|refseq:NP_057863.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) refseq:NP_115805.1|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:0031982"(vesicle)|go:"GO:0051013"(microtubule severing)|go:"GO:0051168"(nuclear export)|go:"GO:0051255"(spindle midzone assembly)|go:"GO:0060682"(primary ureteric bud growth)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR028597|mint:Q9BRK4|ensembl:ENSG00000107816(gene)|ensembl:ENST00000370220(transcript)|ensembl:ENST00000370223(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|refseq:XP_016872269.1|refseq:NP_001305028.1|refseq:NP_001305029.1|refseq:NP_001305030.1|refseq:XP_005270279.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:Jg3y2XqUP/JBerfBYcxMesTuQFQ11927 rogid:OaMJmnmfm6JniKUJeyg7fS6zRcw9606 intact-crc:05A9280A6FC17A6B|rigid:qKnVDPtBw11oLxC2439IbDFJUWA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C206 uniprotkb:Q9BRK4 intact:EBI-9675596|uniprotkb:O56230 intact:EBI-741037|ensembl:ENSP00000359240|ensembl:ENSP00000359243|uniprotkb:Q8N3I0|uniprotkb:Q96J79|uniprotkb:Q96JL2|uniprotkb:B1AL14|uniprotkb:D3DR72 psi-mi:rex_htl1c(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-1(gene name synonym)|uniprotkb:p27Rex(gene name synonym) psi-mi:lzts2_human(display_long)|uniprotkb:Protein LAPSER1(gene name synonym)|uniprotkb:LZTS2(gene name)|psi-mi:LZTS2(display_short)|uniprotkb:KIAA1813(gene name synonym)|uniprotkb:LAPSER1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675678|imex:IM-22977-29 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1EXY|refseq:NP_057863.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) refseq:NP_115805.1|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:0031982"(vesicle)|go:"GO:0051013"(microtubule severing)|go:"GO:0051168"(nuclear export)|go:"GO:0051255"(spindle midzone assembly)|go:"GO:0060682"(primary ureteric bud growth)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR028597|mint:Q9BRK4|ensembl:ENSG00000107816(gene)|ensembl:ENST00000370220(transcript)|ensembl:ENST00000370223(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|refseq:XP_016872269.1|refseq:NP_001305028.1|refseq:NP_001305029.1|refseq:NP_001305030.1|refseq:XP_005270279.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:Jg3y2XqUP/JBerfBYcxMesTuQFQ11927 rogid:OaMJmnmfm6JniKUJeyg7fS6zRcw9606 intact-crc:7DA571E378298B25|rigid:qKnVDPtBw11oLxC2439IbDFJUWA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C206 uniprotkb:Q8N3Z6 intact:EBI-9675596|uniprotkb:O56230 intact:EBI-7265024|uniprotkb:Q9P0F0|uniprotkb:Q8TBK8|uniprotkb:Q8N2M1|uniprotkb:Q5T0Q9|uniprotkb:D3DRQ0|uniprotkb:Q9H648|uniprotkb:Q8N4J2|uniprotkb:Q5T0Q8|intact:MINT-1182798|uniprotkb:B2RCI4|uniprotkb:Q5T0R0|ensembl:ENSP00000337839|ensembl:ENSP00000443113 psi-mi:rex_htl1c(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-1(gene name synonym)|uniprotkb:p27Rex(gene name synonym) psi-mi:zchc7_human(display_long)|uniprotkb:ZCCHC7(gene name)|psi-mi:ZCCHC7(display_short)|uniprotkb:TRAMP-like complex RNA-binding factor ZCCHC7(gene name synonym)|uniprotkb:HSPC086(orf name) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675673|imex:IM-22977-28 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1EXY|refseq:NP_057863.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) refseq:NP_115602.2|refseq:XP_005251665.1|refseq:XP_005251669.1|ensembl:ENSG00000147905(gene)|ensembl:ENST00000336755(transcript)|ensembl:ENST00000534928(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036875|refseq:NP_001276048.1|refseq:NP_001276049.1|refseq:NP_001276050.1 psi-mi:"MI:0471"(mint) - comment:mint|comment:homomint figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:Jg3y2XqUP/JBerfBYcxMesTuQFQ11927 rogid:zm8NMOhdnKspXWuNvY/gjLTMQcI9606 intact-crc:C0FA670CBFB8FCF7|rigid:mWavqKwWQSDYdLFgkXFfSaIT95w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C206 uniprotkb:P63279 intact:EBI-9675596|uniprotkb:O56230 intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69 psi-mi:rex_htl1c(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-1(gene name synonym)|uniprotkb:p27Rex(gene name synonym) psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675668|imex:IM-22977-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1EXY|refseq:NP_057863.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:Jg3y2XqUP/JBerfBYcxMesTuQFQ11927 rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606 intact-crc:AE16299B31CACB92|rigid:oGQ0JrQU9ht9/aRdjBi/8l9qCbo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C206 uniprotkb:O75928 intact:EBI-9675596|uniprotkb:O56230 intact:EBI-348555|uniprotkb:O75927|uniprotkb:Q96BT5|uniprotkb:Q96KE3|ensembl:ENSP00000465676 psi-mi:rex_htl1c(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-1(gene name synonym)|uniprotkb:p27Rex(gene name synonym) psi-mi:pias2_human(display_long)|uniprotkb:Protein inhibitor of activated STAT x(gene name synonym)|uniprotkb:Msx-interacting zinc finger protein(gene name synonym)|uniprotkb:DAB2-interacting protein(gene name synonym)|uniprotkb:Androgen receptor-interacting protein 3(gene name synonym)|uniprotkb:PIAS-NY protein(gene name synonym)|uniprotkb:PIAS2(gene name)|psi-mi:PIAS2(display_short)|uniprotkb:Protein inhibitor of activated STAT2(gene name synonym)|uniprotkb:PIASX(gene name synonym)|uniprotkb:E3 SUMO-protein transferase PIAS2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675693|imex:IM-22977-32 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1EXY|refseq:NP_057863.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) refseq:NP_004662.2|refseq:NP_775298.1|refseq:NP_001310989.1|ensembl:ENSG00000078043(gene)|ensembl:ENST00000585916(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023321|interpro:IPR027228|interpro:IPR036361|interpro:IPR038654|mint:O75928|rcsb pdb:2ASQ|rcsb pdb:4FO9|reactome:R-HSA-3108214|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-4090294 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:Jg3y2XqUP/JBerfBYcxMesTuQFQ11927 rogid:/7gObRzCbafNTNMKe8leGG/h2NQ9606 intact-crc:F4850D3954068CCE|rigid:gBuzMlGhQBqSDVhh2EIOpj6h0bc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:Q9UI95 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-77889|ensembl:ENSP00000235310|ensembl:ENSP00000365855|ensembl:ENSP00000365882|uniprotkb:Q5TGW7|uniprotkb:Q9UNA7|uniprotkb:Q9Y6I6|uniprotkb:B3KNE3 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:md2l2_human(display_long)|uniprotkb:MAD2L2(gene name)|psi-mi:MAD2L2(display_short)|uniprotkb:MAD2B(gene name synonym)|uniprotkb:REV7(gene name synonym)|uniprotkb:Mitotic arrest deficient 2-like protein 2(gene name synonym)|uniprotkb:REV7 homolog(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675705|imex:IM-22977-34 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) ensembl:ENSG00000116670(gene)|ensembl:ENST00000235310(transcript)|ensembl:ENST00000376667(transcript)|ensembl:ENST00000376692(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007015"(actin filament organization)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0016035"(zeta DNA polymerase complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042772"(DNA damage response, signal transduction resulting in transcription)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR036570|rcsb pdb:3ABD|rcsb pdb:3ABE|rcsb pdb:3VU7|rcsb pdb:4EXT|rcsb pdb:4GK0|rcsb pdb:4GK5|rcsb pdb:5XPT|rcsb pdb:5XPU|rcsb pdb:6BC8|rcsb pdb:6BCD|rcsb pdb:6BI7|rcsb pdb:6K07|rcsb pdb:6K08|rcsb pdb:6KEA|rcsb pdb:6KTO|rcsb pdb:6M7A|rcsb pdb:6M7B|rcsb pdb:6NIF|rcsb pdb:6VE5|rcsb pdb:6WS0|rcsb pdb:6WS5|rcsb pdb:6WW9|rcsb pdb:6WWA|rcsb pdb:7L9P|reactome:R-HSA-110312|reactome:R-HSA-5655862|reactome:R-HSA-5656121|refseq:NP_001120797.1|refseq:NP_006332.3|refseq:XP_011538809.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:KBeawMhcP3iXUel74pUDl85A/vw9606 intact-crc:A98F19FA8231EED0|rigid:AQVllxvjOHfIELZFBe7Hetk+tWo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:Q5T8I9 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-9675710|uniprotkb:Q96NN0|uniprotkb:B1AM16|uniprotkb:B1AM17|uniprotkb:Q96EJ7|uniprotkb:A8MRR6|ensembl:ENSP00000359049|ensembl:ENSP00000385655|ensembl:ENSP00000499017 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:henmt_human(display_long)|uniprotkb:HENMT1(gene name)|psi-mi:HENMT1(display_short)|uniprotkb:C1orf59(gene name synonym)|uniprotkb:HEN1 methyltransferase homolog 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675719|imex:IM-22977-35 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_001096062.1|refseq:NP_653185.2|ensembl:ENSG00000162639(gene)|ensembl:ENST00000370032(transcript)|ensembl:ENST00000402983(transcript)|ensembl:ENST00000651461(transcript)|go:"GO:0001510"(RNA methylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008171"(O-methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0034587"(piRNA metabolic process)|go:"GO:0043186"(P granule)|go:"GO:0046872"(metal ion binding)|go:"GO:0090486"(small RNA 2'-O-methyltransferase)|interpro:IPR026610|interpro:IPR029063|rcsb pdb:4XCX|rcsb pdb:5WY0|reactome:R-HSA-5601884 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:UXyyHUVxIewQH/NZwBful5PQcvc9606 intact-crc:4A4790F510D991C1|rigid:Y+xqm/GixGdNWYkZ1cq8BBVqe7k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:O14595 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-2802973|uniprotkb:Q6NZY3|uniprotkb:Q9UEX1|uniprotkb:A8K5H4|uniprotkb:Q53ZR2|ensembl:ENSP00000381148 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:ctds2_human(display_long)|uniprotkb:NIF2(gene name synonym)|uniprotkb:OS4(gene name synonym)|uniprotkb:SCP2(gene name synonym)|uniprotkb:Nuclear LIM interactor-interacting factor 2(gene name synonym)|uniprotkb:Protein OS-4(gene name synonym)|uniprotkb:Small C-terminal domain phosphatase 2(gene name synonym)|uniprotkb:Small CTD phosphatase 2(gene name synonym)|uniprotkb:CTDSP2(gene name)|psi-mi:CTDSP2(display_short) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675700|imex:IM-22977-33 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_005721.3|interpro:IPR011948(Dullard-like phosphatase domain)|interpro:IPR023214|interpro:IPR036412|interpro:IPR040078|mint:O14595|rcsb pdb:2Q5E|reactome:R-HSA-381038|ensembl:ENSG00000175215(gene)|ensembl:ENST00000398073(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008420"(RNA polymerase II CTD heptapeptide repeat phosphatase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR004274(NLI interacting factor)|dip:DIP-61245N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:aYyUZE/wrtAyE4rMDaGGO8pNkYw9606 intact-crc:CEFBB795D5E6275A|rigid:/M5HrXG7bQFk58qqPumO178/aCU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8WW34 uniprotkb:P14079 intact:EBI-9675724|uniprotkb:Q5JY54|uniprotkb:Q6ZU23|ensembl:ENSP00000354312 intact:EBI-9675698|uniprotkb:O56231 psi-mi:tm239_human(display_long)|uniprotkb:TMEM239(gene name)|psi-mi:TMEM239(display_short) psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675730|imex:IM-22977-36 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001305136.1|refseq:XP_011527431.1|refseq:NP_001161142.1|ensembl:ENSG00000198326(gene)|ensembl:ENST00000361033(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR031694 interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:/IAp0KVUESWppSZWM55RQ+08om09606 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 intact-crc:5A231C185F8B1068|rigid:lazUsuvTmR9UCvjhtsXBj5ny5YA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:Q6NYC8 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-2557469|uniprotkb:A8MSS7|uniprotkb:Q8NDQ4|uniprotkb:A2AIB8|uniprotkb:Q9BRL9|uniprotkb:B7ZCV7|uniprotkb:Q8TF52|uniprotkb:Q6ZUJ6|uniprotkb:Q68CK8|uniprotkb:A4UBI6|uniprotkb:A6NCB7|uniprotkb:A2AB01|uniprotkb:Q6ZTV1|ensembl:ENSP00000274853|ensembl:ENSP00000373067|ensembl:ENSP00000382150|ensembl:ENSP00000383400|ensembl:ENSP00000388790|ensembl:ENSP00000400129|ensembl:ENSP00000400990|ensembl:ENSP00000404066|ensembl:ENSP00000405234|ensembl:ENSP00000412456|ensembl:ENSP00000413596|ensembl:ENSP00000416648|ensembl:ENSP00000480270 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:ppr18_human(display_long)|uniprotkb:PPP1R18(gene name)|psi-mi:PPP1R18(display_short)|uniprotkb:HKMT1098(gene name synonym)|uniprotkb:KIAA1949(gene name synonym)|uniprotkb:Protein phosphatase 1 F-actin cytoskeleton-targeting subunit(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 18(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675750|imex:IM-22977-40 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_001128342.1|refseq:NP_597728.1|ensembl:ENSG00000146112(gene)|ensembl:ENSG00000206485(gene)|ensembl:ENSG00000225060(gene)|ensembl:ENSG00000229998(gene)|ensembl:ENST00000274853(transcript)|ensembl:ENST00000383573(transcript)|ensembl:ENST00000399199(transcript)|ensembl:ENST00000400554(transcript)|ensembl:ENST00000437121(transcript)|ensembl:ENST00000438815(transcript)|ensembl:ENST00000438945(transcript)|ensembl:ENSG00000230341(gene)|ensembl:ENST00000443517(transcript)|ensembl:ENSG00000234000(gene)|ensembl:ENST00000444206(transcript)|ensembl:ENST00000449705(transcript)|ensembl:ENST00000451544(transcript)|ensembl:ENST00000455935(transcript)|ensembl:ENST00000615527(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0019902"(phosphatase binding)|interpro:IPR025903|interpro:IPR025907|interpro:IPR026671|mint:Q6NYC8 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:63zpNZuwQb7VD0pOrr6yaRpPNmA9606 intact-crc:9F167CC56024BB38|rigid:tCmMeavhf6cC5sotfoHYwwQBlnY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:Q6PF05 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-8656864|ensembl:ENSP00000422188|uniprotkb:Q96LJ2|intact:MINT-8163808|uniprotkb:Q6RGS4|uniprotkb:Q8N7R3|uniprotkb:G8IJH6 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:tt23l_human(display_long)|uniprotkb:TTC23L(gene name)|psi-mi:TTC23L(display_short) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675745|imex:IM-22977-39 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) ensembl:ENSG00000205838(gene)|ensembl:ENST00000505624(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0030496"(midbody)|go:"GO:0034976"(response to endoplasmic reticulum stress)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR042621|mint:Q6PF05|refseq:NP_001304878.1|refseq:NP_653326.3 psi-mi:"MI:0471"(mint) - comment:mint figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:SRndoUysST7RgIovvs89vd30vMk9606 intact-crc:2AFFE2C8FE0B3768|rigid:Tle3OnFVOzKeBMVeCotXaOD/ixI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:Q8N4L8 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-1104933|ensembl:ENSP00000361392|uniprotkb:Q6RWT2 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:ccd24_human(display_long)|uniprotkb:CCDC24(gene name)|psi-mi:CCDC24(display_short) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675740|imex:IM-22977-38 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) ensembl:ENSG00000159214(gene)|ensembl:ENST00000372318(transcript)|go:"GO:0001835"(blastocyst hatching)|interpro:IPR031367|refseq:NP_689712.1|refseq:XP_016855930.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:+WHY6f4VV8Z2uvuWOUYqOSCN36o9606 intact-crc:28C7F9631AE15A21|rigid:CTvhQm5xMNVUURO/CBaTiM24ZHg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:O43186 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-748171|uniprotkb:Q0QD45|ensembl:ENSP00000221996|ensembl:ENSP00000445565 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:crx_human(display_long)|uniprotkb:CRX(gene name)|psi-mi:CRX(display_short)|uniprotkb:CORD2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675735|imex:IM-22977-37 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_000545.1|ensembl:ENSG00000105392(gene)|ensembl:ENST00000221996(transcript)|ensembl:ENST00000539067(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050896"(response to stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:v/bkO/0iLzq1Q2HtieWQQ40RF9M9606 intact-crc:B6F763A54FEB67F1|rigid:FuKIZMUGNIJ0P4hSi3/FF++Rvh4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:Q8N448 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-2340947|uniprotkb:Q6ZMH2|uniprotkb:Q5W0P0|uniprotkb:Q96SH4|ensembl:ENSP00000325929|ensembl:ENSP00000497224 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:lnx2_human(display_long)|uniprotkb:LNX2(gene name)|psi-mi:LNX2(display_short)|uniprotkb:PDZRN1(gene name synonym)|uniprotkb:Numb-binding protein 2(gene name synonym)|uniprotkb:PDZ domain-containing RING finger protein 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675775|imex:IM-22977-45 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_699202.1|refseq:XP_016875923.1|ensembl:ENSG00000139517(gene)|ensembl:ENST00000316334(transcript)|ensembl:ENST00000649248(transcript)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036034|mint:Q8N448|rcsb pdb:2VWR|rcsb pdb:5DIN|rcsb pdb:5E11|rcsb pdb:5E1Y|rcsb pdb:5E21|rcsb pdb:5E22 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:cIS5t4XkbnIgelDlUc692nI285g9606 intact-crc:9532B62C9FD4EF5E|rigid:3kgPaEk7p/HZAs6GpyyrQsws0mg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:P43268 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-6447147|ensembl:ENSP00000321835|ensembl:ENSP00000377273|ensembl:ENSP00000465718|uniprotkb:B7Z5J3|uniprotkb:B7Z9J6|uniprotkb:Q96AW9|uniprotkb:A8K314 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:etv4_human(display_long)|uniprotkb:Adenovirus E1A enhancer-binding protein(gene name synonym)|uniprotkb:E1A-F(gene name synonym)|uniprotkb:E1AF(gene name synonym)|uniprotkb:PEA3(gene name synonym)|uniprotkb:Polyomavirus enhancer activator 3 homolog(gene name synonym)|uniprotkb:ETV4(gene name)|psi-mi:ETV4(display_short) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675755|imex:IM-22977-41 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) ensembl:ENSG00000175832(gene)|ensembl:ENST00000319349(transcript)|ensembl:ENST00000393664(transcript)|ensembl:ENST00000591713(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030154"(cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR006715(PEA3-type ETS-domain transcription factor, N-terminal)|interpro:IPR036388|interpro:IPR036390|rcsb pdb:4UUV|rcsb pdb:5ILU|reactome:R-HSA-5687128|rcsb pdb:4CO8|refseq:NP_001073143.1|refseq:NP_001248366.1|refseq:NP_001248367.1|refseq:NP_001977.1|refseq:NP_001248368.1|dip:DIP-748N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:9CuoBGjLzbo93LSm5yNFuBQlATg9606 intact-crc:2226403F525CBC14|rigid:aSIvNfO1eP2MzxNUKXk5HD5e8uQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:Q8N448 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-2340947|uniprotkb:Q6ZMH2|uniprotkb:Q5W0P0|uniprotkb:Q96SH4|ensembl:ENSP00000325929|ensembl:ENSP00000497224 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:lnx2_human(display_long)|uniprotkb:LNX2(gene name)|psi-mi:LNX2(display_short)|uniprotkb:PDZRN1(gene name synonym)|uniprotkb:Numb-binding protein 2(gene name synonym)|uniprotkb:PDZ domain-containing RING finger protein 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675770|imex:IM-22977-44 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_699202.1|refseq:XP_016875923.1|ensembl:ENSG00000139517(gene)|ensembl:ENST00000316334(transcript)|ensembl:ENST00000649248(transcript)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036034|mint:Q8N448|rcsb pdb:2VWR|rcsb pdb:5DIN|rcsb pdb:5E11|rcsb pdb:5E1Y|rcsb pdb:5E21|rcsb pdb:5E22 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:cIS5t4XkbnIgelDlUc692nI285g9606 intact-crc:ED3EEFC5883C1E10|rigid:3kgPaEk7p/HZAs6GpyyrQsws0mg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:O15287 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-81610|ensembl:ENSP00000367910 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:fancg_human(display_long)|uniprotkb:FANCG(gene name)|psi-mi:FANCG(display_short)|uniprotkb:XRCC9(gene name synonym)|uniprotkb:DNA repair protein XRCC9(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675765|imex:IM-22977-43 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) ensembl:ENSG00000221829(gene)|refseq:NP_004620.1|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007286"(spermatid development)|go:"GO:0009314"(response to radiation)|ensembl:ENST00000378643(transcript)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0043240"(Fanconi anaemia nuclear complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039684|mint:O15287|rcsb pdb:7KZP|rcsb pdb:7KZQ|go:"GO:0001541"(ovarian follicle development)|rcsb pdb:7KZR|go:"GO:0003684"(damaged DNA binding)|rcsb pdb:7KZS|go:"GO:0005654"(nucleoplasm)|rcsb pdb:7KZT|rcsb pdb:7KZV|reactome:R-HSA-6783310|go:"GO:0005730"(nucleolus) psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:jVGeic2vn/qrZgro3IKXWhNteHo9606 intact-crc:CEFB412DD4BA465A|rigid:VUsCUWR++GF76Fc8mT3LpR/eMV0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:Q8IZQ1 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-1569256|uniprotkb:Q4W5K5|uniprotkb:Q6P0Q5|uniprotkb:Q8N1T2|uniprotkb:Q8NAV6|uniprotkb:Q96BS7|uniprotkb:Q96D33|uniprotkb:Q96N85|uniprotkb:Q9Y2J7|ensembl:ENSP00000295888 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:wdfy3_human(display_long)|uniprotkb:Autophagy-linked FYVE protein(gene name synonym)|uniprotkb:WDFY3(gene name)|psi-mi:WDFY3(display_short)|uniprotkb:KIAA0993(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675780|imex:IM-22977-46 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_055806.2|refseq:XP_011530065.1|refseq:XP_011530067.1|ensembl:ENSG00000163625(gene)|ensembl:ENST00000295888(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016605"(PML body)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035973"(aggrephagy)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR019775|interpro:IPR023362|interpro:IPR036322|interpro:IPR036372|mint:Q8IZQ1|rcsb pdb:3WIM|rcsb pdb:6W9N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:yVIfhD/TU9JhrQR8WCChT4Jpi8c9606 intact-crc:74C00DF6A4084002|rigid:oCtNq/MukZ+J4BT1dPOIPMFLnno false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:Q9H4K1 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-740128|uniprotkb:Q6ICD0|uniprotkb:Q9Y413|ensembl:ENSP00000483356|uniprotkb:A0A087X0F7 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:ribc2_human(display_long)|uniprotkb:RIBC2(gene name)|psi-mi:RIBC2(display_short)|uniprotkb:C22orf11(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675785|imex:IM-22977-47 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) ensembl:ENSG00000128408(gene)|ensembl:ENST00000614167(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR008805(RIB43A)|refseq:XP_005261581.1|refseq:NP_056468.3 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2019/11/14 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:rU6ggF8fZGGy7ICGFHxeMZQLkw49606 intact-crc:67C4EBA7FE17CEE2|rigid:jBn3FS21nDC+gzVuol8QDxilLn4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:Q01844 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-739737|uniprotkb:Q92635|uniprotkb:Q96FE8|uniprotkb:Q96MX4|uniprotkb:Q9BWA2|uniprotkb:Q5THL0|intact:EBI-28987207|ensembl:ENSP00000381031|intact:EBI-10985407|uniprotkb:B0QYK1|uniprotkb:Q96MN4 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:ews_human(display_long)|uniprotkb:EWSR1(gene name)|psi-mi:EWSR1(display_short)|uniprotkb:EWS(gene name synonym)|uniprotkb:EWS oncogene(gene name synonym)|uniprotkb:Ewing sarcoma breakpoint region 1 protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675760|imex:IM-22977-42 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_001156757.1|refseq:NP_005234.1|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q01844|rcsb pdb:2CPE|interpro:IPR001876(Zinc finger, RanBP2-type)|ensembl:ENSG00000182944(gene)|ensembl:ENST00000397938(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001156759.1|refseq:NP_053733.2|refseq:NP_001156758.1|ensembl:ENST00000332035|ensembl:ENSP00000331699|ensembl:ENST00000333395|ensembl:ENSP00000327456|ensembl:ENSP00000381031|ensembl:ENST00000406548|ensembl:ENSP00000385726|ensembl:ENST00000414183|ensembl:ENSP00000400142|dip:DIP-34449N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:7PxoTjcmcdUA3clzf0eW+iCFaS49606 intact-crc:5BA46271BAAF9455|rigid:W1Y++AnlhlHy57P93jLHoPiQVx8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:P02538 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-702198|uniprotkb:P48667|uniprotkb:Q08AR4|uniprotkb:Q6NT67|uniprotkb:Q96CL4|uniprotkb:A4QPC1|ensembl:ENSP00000369317 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:k2c6a_human(display_long)|uniprotkb:Cytokeratin-6A(gene name synonym)|uniprotkb:Keratin-6A(gene name synonym)|uniprotkb:Cytokeratin-6D(gene name synonym)|uniprotkb:KRT6A(gene name)|psi-mi:KRT6A(display_short)|uniprotkb:K6A(gene name synonym)|uniprotkb:KRT6D(gene name synonym)|uniprotkb:Type-II keratin Kb6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675822|imex:IM-22977-52 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_005545.1|dip:DIP-533N|ensembl:ENSG00000205420(gene)|ensembl:ENST00000330722(transcript)|go:"GO:0001899"(negative regulation of cytolysis by symbiont of host cells)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0042060"(wound healing)|go:"GO:0045095"(keratin filament)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051838"(cytolysis by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000536"(negative regulation of entry of bacterium into host cell)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|mint:P02538|rcsb pdb:5KI0|reactome:R-HSA-6805567|reactome:R-HSA-6809371 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:feIxUFTSMnjattUda5vdGhiL9H89606 intact-crc:EA69F9551EFD1F36|rigid:apTyTuUgTkDGDy+Rz4ocMLr+PHc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:P17482 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-745290|uniprotkb:Q9H1I1|uniprotkb:B2RDB7|ensembl:ENSP00000309439 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:hxb9_human(display_long)|uniprotkb:Homeobox protein Hox-2E(gene name synonym)|uniprotkb:Homeobox protein Hox-2.5(gene name synonym)|uniprotkb:HOXB9(gene name)|psi-mi:HOXB9(display_short)|uniprotkb:HOX2E(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675812|imex:IM-22977-50 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_076922.1|ensembl:ENSG00000170689(gene)|ensembl:ENST00000311177(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0030879"(mammary gland development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006711(Hox9 activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017112(Homeobox, Hox9)|interpro:IPR017970|interpro:IPR020479|mint:P17482 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:1pOMN5hO0W2eq4PII7uRN7EZ7DY9606 intact-crc:A859933493100892|rigid:oY0MEygEOSObMcI0BiNFhUcwoAI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:Q6PF18 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-9675802|uniprotkb:Q86YQ9|ensembl:ENSP00000347486 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:morn3_human(display_long)|uniprotkb:MORN3(gene name)|psi-mi:MORN3(display_short) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675807|imex:IM-22977-49 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_776254.3|refseq:XP_005253926.1|refseq:XP_011536515.1|ensembl:ENSG00000139714(gene)|ensembl:ENST00000355329(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR003409(MORN motif) psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:DqvOxujxoozjpdQzRPQrZurWHY09606 intact-crc:BA5CADEE5DBF5A80|rigid:NI6zQlnJDA+4KGe0fV628ScgQbg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:Q9NP87 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-9675790|uniprotkb:Q86WQ9|uniprotkb:D3DVK4|uniprotkb:Q6P5X8|ensembl:ENSP00000242248 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:dpolm_human(display_long)|uniprotkb:POLM(gene name)|psi-mi:POLM(display_short)|uniprotkb:Terminal transferase(gene name synonym)|uniprotkb:polmu(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675797|imex:IM-22977-48 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_001271259.1|refseq:NP_001271260.1|refseq:NP_037416.1|rcsb pdb:6IPK|rcsb pdb:6IPL|rcsb pdb:6IPM|rcsb pdb:6IPN|rcsb pdb:6P1M|rcsb pdb:6P1N|rcsb pdb:6P1O|rcsb pdb:6P1P|rcsb pdb:6P1Q|rcsb pdb:6P1R|rcsb pdb:6P1S|rcsb pdb:6P1T|rcsb pdb:6P1U|rcsb pdb:6P1V|rcsb pdb:6P1W|rcsb pdb:6WIC|rcsb pdb:6WID|rcsb pdb:6WIE|rcsb pdb:7CO6|rcsb pdb:7CO8|rcsb pdb:7CO9|rcsb pdb:7COA|rcsb pdb:7COB|rcsb pdb:7COC|rcsb pdb:7COD|reactome:R-HSA-5693571|ensembl:ENSG00000122678(gene)|ensembl:ENST00000242248(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|interpro:IPR001357(BRCT)|interpro:IPR001726(DNA nucleotidylexotransferase)|interpro:IPR002054(DNA-directed DNA polymerase, family X)|interpro:IPR010996(DNA-directed DNA polymerase, family X, beta-like, N-terminal)|interpro:IPR018944|interpro:IPR019843|interpro:IPR022312|interpro:IPR027249|interpro:IPR027421|interpro:IPR028207|interpro:IPR029398|interpro:IPR036420|interpro:IPR037160|interpro:IPR043519|rcsb pdb:2DUN|rcsb pdb:2HTF|rcsb pdb:4LZD|rcsb pdb:4LZG|rcsb pdb:4M04|rcsb pdb:4M0A|rcsb pdb:4YCX|rcsb pdb:4YD1|rcsb pdb:4YD2|rcsb pdb:5TWP|rcsb pdb:5TWQ|rcsb pdb:5TWR|rcsb pdb:5TWS|rcsb pdb:5TXX|rcsb pdb:5TXZ|rcsb pdb:5TYB|rcsb pdb:5TYC|rcsb pdb:5TYD|rcsb pdb:5TYE|rcsb pdb:5TYF|rcsb pdb:5TYG|rcsb pdb:5TYU|rcsb pdb:5TYV|rcsb pdb:5TYW|rcsb pdb:5TYX|rcsb pdb:5TYY|rcsb pdb:5TYZ|rcsb pdb:5VZ7|rcsb pdb:5VZ8|rcsb pdb:5VZ9|rcsb pdb:5VZA|rcsb pdb:5VZB|rcsb pdb:5VZC|rcsb pdb:5VZD|rcsb pdb:5VZE|rcsb pdb:5VZF|rcsb pdb:5VZG|rcsb pdb:5VZH|rcsb pdb:5VZI|rcsb pdb:5W4F|rcsb pdb:5ZLC|rcsb pdb:6AEC|rcsb pdb:6AEH|rcsb pdb:6AK5|rcsb pdb:6AK6|rcsb pdb:6AK8|rcsb pdb:6AK9|rcsb pdb:6AKH|rcsb pdb:6IPD|rcsb pdb:6IPE|rcsb pdb:6IPF|rcsb pdb:6IPG|rcsb pdb:6IPH|rcsb pdb:6IPI|rcsb pdb:6IPJ psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:PjYb9sk0XvVaJwJ3JdGQY4IvenE9606 intact-crc:97FEB20C74AE33C7|rigid:nZA7YVznR+9uH7ecylRKeQjBF8k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:P19013 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-2371606|uniprotkb:Q6GTR8|uniprotkb:Q96LA7|uniprotkb:Q9BTL1|intact:EBI-22121113|uniprotkb:B4DRS2|uniprotkb:F8VS64|intact:EBI-22010019|intact:EBI-28973341|ensembl:ENSP00000448220 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:k2c4_human(display_long)|uniprotkb:KRT4(gene name)|psi-mi:KRT4(display_short)|uniprotkb:CYK4(gene name synonym)|uniprotkb:Cytokeratin-4(gene name synonym)|uniprotkb:Keratin-4(gene name synonym)|uniprotkb:Type-II keratin Kb4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675817|imex:IM-22977-51 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) ensembl:ENSP00000448220|refseq:NP_002263.3|ensembl:ENSG00000170477(gene)|ensembl:ENST00000551956(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0009986"(cell surface)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0045095"(keratin filament)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|mint:P19013|reactome:R-HSA-6805567|reactome:R-HSA-6809371 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2020/03/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:WBLRjdlqvNYbC7R2ZSNON6QLcOU9606 intact-crc:1BE81823D2B6F890|rigid:Wnd+0bdcXFGiZEIPOUvcc1+px8U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:P19012 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675832|imex:IM-22977-54 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606 intact-crc:B260CED14060A3EA|rigid:RR3ow1wldjtVSxYngkmxlWNhEyM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:P05787 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-297852|uniprotkb:Q14099|uniprotkb:Q14716|uniprotkb:Q14717|uniprotkb:Q53GJ0|uniprotkb:Q6DHW5|uniprotkb:Q6GMY0|uniprotkb:Q6P4C7|uniprotkb:Q96J60|ensembl:ENSP00000293308|ensembl:ENSP00000447402|ensembl:ENSP00000447566|uniprotkb:A8K4H3|uniprotkb:B0AZN5|uniprotkb:F8VXB4 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:k2c8_human(display_long)|uniprotkb:Keratin-8(gene name synonym)|uniprotkb:KRT8(gene name)|psi-mi:KRT8(display_short)|uniprotkb:CYK8(gene name synonym)|uniprotkb:Cytokeratin-8(gene name synonym)|uniprotkb:Type-II keratin Kb8(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675827|imex:IM-22977-53 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_001243222.1|ensembl:ENSG00000170421(gene)|ensembl:ENST00000293308(transcript)|ensembl:ENST00000546897(transcript)|ensembl:ENST00000552551(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005911"(cell-cell junction)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030018"(Z disc)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045095"(keratin filament)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051599"(response to hydrostatic pressure)|go:"GO:0051707"(response to other organism)|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097284"(hepatocyte apoptotic process)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|mint:P05787|reactome:R-HSA-6805567|reactome:R-HSA-6809371|refseq:NP_002264.1|dip:DIP-424N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:zyV8eOjx426ehjJYK4jsizORUws9606 intact-crc:EA6B412C425F3836|rigid:x7czc5DkQYDo3LHUx9TWiA9EhDY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:Q6PEX3 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-3957672|ensembl:ENSP00000353742|uniprotkb:B0RZD3 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:kr261_human(display_long)|uniprotkb:KRTAP26-1(gene name)|psi-mi:KRTAP26-1(display_short)|uniprotkb:KAP26.1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675837|imex:IM-22977-55 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) ensembl:ENSG00000197683(gene)|ensembl:ENST00000360542(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|interpro:IPR007951(PMG)|reactome:R-HSA-6805567|refseq:NP_981950.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:VKgQPRg2qO2FXQx0fQ/dd/5kMws9606 intact-crc:2A58AC4B5B2EEA02|rigid:+5jUHKk7X2WXFr/jH8bKukyHA9c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:P07196 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-475646|uniprotkb:Q16154|uniprotkb:B9ZVN2|uniprotkb:Q8IU72|ensembl:ENSP00000482169 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:nfl_human(display_long)|uniprotkb:Neurofilament triplet L protein(gene name synonym)|uniprotkb:68 kDa neurofilament protein(gene name synonym)|uniprotkb:NEFL(gene name)|psi-mi:NEFL(display_short)|uniprotkb:NF68(gene name synonym)|uniprotkb:NFL(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675842|imex:IM-22977-56 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_006149.2|ensembl:ENSG00000277586(gene)|ensembl:ENST00000610854(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005883"(neurofilament)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031133"(regulation of axon diameter)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0030426"(growth cone)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045105"(intermediate filament polymerization or depolymerization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051258"(protein polymerization)|go:"GO:0051412"(response to corticosterone)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0060074"(synapse maturation)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:0099182"(presynaptic intermediate filament cytoskeleton)|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton)|go:"GO:1903935"(response to sodium arsenite)|go:"GO:1903937"(response to acrylamide)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027692|interpro:IPR039008|mint:P07196|reactome:R-HSA-438066|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:tgdjWnqcql4YMbd89ujbDoqN/Yg9606 intact-crc:926763DE2F070B78|rigid:6OwJJGC5AlyUzGbTEhKg6wK+2uc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:P07196 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-475646|uniprotkb:Q16154|uniprotkb:B9ZVN2|uniprotkb:Q8IU72|ensembl:ENSP00000482169 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:nfl_human(display_long)|uniprotkb:Neurofilament triplet L protein(gene name synonym)|uniprotkb:68 kDa neurofilament protein(gene name synonym)|uniprotkb:NEFL(gene name)|psi-mi:NEFL(display_short)|uniprotkb:NF68(gene name synonym)|uniprotkb:NFL(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675847|imex:IM-22977-57 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_006149.2|ensembl:ENSG00000277586(gene)|ensembl:ENST00000610854(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005883"(neurofilament)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031133"(regulation of axon diameter)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0030426"(growth cone)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045105"(intermediate filament polymerization or depolymerization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051258"(protein polymerization)|go:"GO:0051412"(response to corticosterone)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0060074"(synapse maturation)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:0099182"(presynaptic intermediate filament cytoskeleton)|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton)|go:"GO:1903935"(response to sodium arsenite)|go:"GO:1903937"(response to acrylamide)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027692|interpro:IPR039008|mint:P07196|reactome:R-HSA-438066|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:tgdjWnqcql4YMbd89ujbDoqN/Yg9606 intact-crc:EA6B3A3738EFFA36|rigid:6OwJJGC5AlyUzGbTEhKg6wK+2uc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29474 uniprotkb:P14079 intact:EBI-1391623|uniprotkb:A0S0A7|uniprotkb:E9PFR2|uniprotkb:Q13662|uniprotkb:Q14251|uniprotkb:Q14434|uniprotkb:Q6GSL5|uniprotkb:A8KA63|uniprotkb:B2RCQ1|uniprotkb:Q548C1|uniprotkb:Q9UDC6|uniprotkb:A0S0A8|ensembl:ENSP00000297494 intact:EBI-9675698|uniprotkb:O56231 psi-mi:nos3_human(display_long)|uniprotkb:Endothelial NOS(gene name synonym)|uniprotkb:EC-NOS(gene name synonym)|uniprotkb:NOS type III(gene name synonym)|uniprotkb:Constitutive NOS(gene name synonym)|uniprotkb:NOS3(gene name)|psi-mi:NOS3(display_short) psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675852|imex:IM-22977-58 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000594.2|refseq:NP_001153581.1|refseq:NP_001153582.1|refseq:NP_001153583.1|refseq:XP_016867721.1|dip:DIP-38479N|ensembl:ENSG00000164867(gene)|go:"GO:0034405"(response to fluid shear stress)|go:"GO:0034617"(tetrahydrobiopterin binding)|go:"GO:0034618"(arginine binding)|go:"GO:0042311"(vasodilation)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050661"(NADP binding)|go:"GO:0070168"(negative regulation of biomineral tissue development)|go:"GO:0097746"(blood vessel diameter maintenance)|ensembl:ENST00000297494(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003100"(regulation of systemic arterial blood pressure by endothelin)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003184"(pulmonary valve morphogenesis)|go:"GO:0003203"(endocardial cushion morphogenesis)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004517"(nitric-oxide synthase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006527"(arginine catabolic process)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007263"(nitric oxide mediated signal transduction)|interpro:IPR001094(Flavodoxin-like)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR004030(Nitric oxide synthase, oxygenase region)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR012144(Nitric-oxide synthase)|interpro:IPR017927|interpro:IPR017938|interpro:IPR023173|interpro:IPR029039|interpro:IPR036119|interpro:IPR039261|mint:P29474|rcsb pdb:1M9J|rcsb pdb:1M9K|rcsb pdb:1M9M|rcsb pdb:1M9Q|rcsb pdb:1M9R|rcsb pdb:1NIW|rcsb pdb:2LL7|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0009725"(response to hormone)|go:"GO:0010181"(FMN binding)|go:"GO:0010544"(negative regulation of platelet activation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014740"(negative regulation of muscle hyperplasia)|go:"GO:0014806"(smooth muscle hyperplasia)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0020037"(heme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031284"(positive regulation of guanylate cyclase activity)|go:"GO:0031644"(regulation of nervous system process)|go:"GO:0032496"(response to lipopolysaccharide)|rcsb pdb:2MG5|rcsb pdb:2N8J|rcsb pdb:3EAH|rcsb pdb:3NOS|rcsb pdb:4D1O|rcsb pdb:4D1P|rcsb pdb:5UO8|rcsb pdb:5UO9|rcsb pdb:5UOA|rcsb pdb:5UOB|rcsb pdb:5UOC|rcsb pdb:5VVB|rcsb pdb:5VVC|rcsb pdb:5VVD|rcsb pdb:5XOF|rcsb pdb:6AV6|rcsb pdb:6AV7|rcsb pdb:6CIE|rcsb pdb:6CIF|rcsb pdb:6NH1|rcsb pdb:6NH2|rcsb pdb:6NH3|rcsb pdb:6NH4|rcsb pdb:6NH5|rcsb pdb:6NH6|rcsb pdb:6NH7|rcsb pdb:6NH8|rcsb pdb:6NHF|rcsb pdb:6POU|rcsb pdb:6POV|rcsb pdb:6POW|rcsb pdb:6POX|rcsb pdb:6POY|rcsb pdb:6POZ|rcsb pdb:6PP0|rcsb pdb:6PP1|rcsb pdb:6PP2|rcsb pdb:6PP3|rcsb pdb:6PP4|reactome:R-HSA-1222556|reactome:R-HSA-1474151|reactome:R-HSA-203615|reactome:R-HSA-203641|reactome:R-HSA-203754|reactome:R-HSA-392154|reactome:R-HSA-5218920|reactome:R-HSA-9009391 interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2018/04/06 rogid:FIvVY2y5ltfs8KVWaMEHCEt2pMk9606 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 intact-crc:37C0A90C1EF2AC35|rigid:EjPL/4tW1FuddaOPDoXBHt3D6NE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9P2K5 uniprotkb:P14079 intact:EBI-9675857|uniprotkb:A7MCZ9|uniprotkb:C9K0J4|uniprotkb:Q9NUQ1|uniprotkb:Q7Z4B7|uniprotkb:C9J921|uniprotkb:Q6NUM5|uniprotkb:Q9H922|uniprotkb:Q7L388 intact:EBI-9675698|uniprotkb:O56231 psi-mi:myef2_human(display_long)|uniprotkb:MYEF2(gene name)|psi-mi:MYEF2(display_short)|uniprotkb:KIAA1341(gene name synonym)|uniprotkb:MST156(gene name synonym) psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675869|imex:IM-22977-59 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_057216.2|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:Q9P2K5|refseq:NP_001288139.1|interpro:IPR034630|interpro:IPR034631|interpro:IPR034632|interpro:IPR035979|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0014902"(myotube differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000815"(regulation of mRNA stability involved in response to oxidative stress) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:v/dNVOlL/ndJDraGpMrPedvq/FU9606 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 intact-crc:C1665B46A43D1CCD|rigid:/kF/tDcEfmVod4PyGORbmdQpgCc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:Q9UK41 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-727424|uniprotkb:Q86VK0|ensembl:ENSP00000292510|ensembl:ENSP00000434064|ensembl:ENSP00000496519|ensembl:ENSP00000496693 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:vps28_human(display_long)|uniprotkb:VPS28(gene name)|psi-mi:VPS28(display_short)|uniprotkb:ESCRT-I complex subunit VPS28(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675874|imex:IM-22977-60 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_057292.1|refseq:NP_898880.1|ensembl:ENSG00000160948(gene)|ensembl:ENSG00000285339(gene)|ensembl:ENST00000292510(transcript)|ensembl:ENST00000526054(transcript)|ensembl:ENST00000642867(transcript)|ensembl:ENST00000643186(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR007143(Vacuolar protein sorting-associated, VPS28)|interpro:IPR017898|interpro:IPR017899|interpro:IPR037202|interpro:IPR037206|interpro:IPR038358|mint:Q9UK41|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:GUcc7bRf1LaLklAYVLEHRSihPjA9606 intact-crc:91D0B45621447D2C|rigid:nhymNDABi2xc9Bnswb/HAVWosyE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:Q9P0T4 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-745520|uniprotkb:B2RDM6|ensembl:ENSP00000270451|ensembl:ENSP00000466047|ensembl:ENSP00000466564 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:zn581_human(display_long)|uniprotkb:ZNF581(gene name)|psi-mi:ZNF581(display_short)|uniprotkb:HSPC189(orf name) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675894|imex:IM-22977-64 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_057619.1|ensembl:ENSG00000171425(gene)|ensembl:ENST00000270451(transcript)|ensembl:ENST00000587252(transcript)|ensembl:ENST00000588537(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9P0T4|go:"GO:0005634"(nucleus)|refseq:XP_006723303.1|refseq:XP_016882356.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:SpE0ZPhcfXB4PnyufoyWq4iNAs89606 intact-crc:3994047019D51A20|rigid:OirJ8/gCqK7sI2xk3QhYekBrmTQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:Q969H6 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-366525|uniprotkb:Q53FS5|uniprotkb:Q9Y2Q6|uniprotkb:A6NL80|ensembl:ENSP00000350098 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:pop5_human(display_long)|uniprotkb:POP5(gene name)|psi-mi:POP5(display_short)|uniprotkb:AD-008(orf name)|uniprotkb:HSPC004(orf name)|uniprotkb:x0003(orf name) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675889|imex:IM-22977-63 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_057002.2|refseq:NP_937845.1|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|interpro:IPR002759(Ribonuclease P-related)|interpro:IPR016819(Ribonuclease P/MRP protein, subunit Pop5)|interpro:IPR038085|rcsb pdb:6AHR|rcsb pdb:6AHU|reactome:R-HSA-6784531|ensembl:ENSG00000167272(gene)|ensembl:ENST00000357500(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0005730"(nucleolus) psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:WYNesu92ICtpEM2lwO63c6hjcMY9606 intact-crc:A56C8756D6E5BF89|rigid:7kmKU2Wq9Vx9Pjq7tIQ45iPlo3g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:Q9BPX1 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-742664|uniprotkb:Q9UKU3|ensembl:ENSP00000263278 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:dhb14_human(display_long)|uniprotkb:DHRS10(gene name synonym)|uniprotkb:Dehydrogenase/reductase SDR family member 10(gene name synonym)|uniprotkb:17-beta-hydroxysteroid dehydrogenase DHRS10(gene name synonym)|uniprotkb:Retinal short-chain dehydrogenase/reductase retSDR3(gene name synonym)|uniprotkb:HSD17B14(gene name)|psi-mi:HSD17B14(display_short)|uniprotkb:SDR3(gene name synonym)|uniprotkb:SDR47C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 47C member 1(gene name synonym)|uniprotkb:UNQ502/PRO474(orf name) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675879|imex:IM-22977-61 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_057330.2|ensembl:ENSG00000087076(gene)|ensembl:ENST00000263278(transcript)|go:"GO:0004303"(estradiol 17-beta-dehydrogenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006706"(steroid catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047045"("testosterone 17-beta-dehydrogenase (NADP+) activity")|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|rcsb pdb:1YDE|rcsb pdb:5EN4|rcsb pdb:5HS6|rcsb pdb:5ICM|rcsb pdb:5ICS|rcsb pdb:5JS6|rcsb pdb:5JSF|rcsb pdb:5L7T|rcsb pdb:5L7W|rcsb pdb:5L7Y|rcsb pdb:5O42|rcsb pdb:5O43|rcsb pdb:5O6O|rcsb pdb:5O6X|rcsb pdb:5O6Z|rcsb pdb:5O72|rcsb pdb:5O7C|rcsb pdb:6EMM|rcsb pdb:6FFB|rcsb pdb:6G4L|rcsb pdb:6GBT|rcsb pdb:6GTB|rcsb pdb:6GTU|rcsb pdb:6H0M|rcsb pdb:6HNO|rcsb pdb:6QCK|rcsb pdb:6ZDE|rcsb pdb:6ZDI|reactome:R-HSA-193144 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:/t03kHO/EWlqKNv7+TkWbTV9jpM9606 intact-crc:E78D9EB0AACA2682|rigid:O0MxVr8hCLOVRXTikI9Ms/s4NVc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:Q9NZD8 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-742688|uniprotkb:B4DW44|uniprotkb:Q6ZMB6|ensembl:ENSP00000204566|ensembl:ENSP00000404111 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:spg21_human(display_long)|uniprotkb:Spastic paraplegia 21 autosomal recessive Mast syndrome protein(gene name synonym)|uniprotkb:Acid cluster protein 33(gene name synonym)|uniprotkb:SPG21(gene name)|psi-mi:SPG21(display_short)|uniprotkb:ACP33(gene name synonym)|uniprotkb:BM-019(orf name)|uniprotkb:GL010(orf name)|uniprotkb:Spastic paraplegia 21 protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675884|imex:IM-22977-62 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_001121361.1|refseq:NP_001121362.1|refseq:NP_057714.1|ensembl:ENSG00000090487(gene)|ensembl:ENST00000204566(transcript)|ensembl:ENST00000433215(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR026151|interpro:IPR029058|mint:Q9NZD8|refseq:XP_005254494.1|refseq:XP_016877786.1|refseq:XP_016877787.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:MoKySBpEYFNm7Lox/HM5nnkmhkA9606 intact-crc:293895CC4B2858B3|rigid:0JtDal2rUCd9gNxrsnD2qQXZftU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:Q9NX63 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-743375|ensembl:ENSP00000262570 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:mic19_human(display_long)|uniprotkb:CHCHD3(gene name)|psi-mi:CHCHD3(display_short)|uniprotkb:MINOS3(gene name synonym)|uniprotkb:Coiled-coil-helix-coiled-coil-helix domain-containing protein 3(gene name synonym)|uniprotkb:MIC19(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675899|imex:IM-22977-65 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) go:"GO:0008053"(mitochondrial fusion)|refseq:NP_060282.1|refseq:NP_001304106.1|ensembl:ENSG00000106554(gene)|ensembl:ENST00000262570(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0042407"(cristae formation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061617"(MICOS complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140275"(MIB complex)|mint:Q9NX63|reactome:R-HSA-1268020|reactome:R-HSA-8949613|go:"GO:0019902"(phosphatase binding) psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:Ox0+PoTPYwxw8cKNqpzvSCg+Smg9606 intact-crc:D55D3D1C9DBFC04D|rigid:KVsO9LcpE80tfk+Oojaewfgh4zo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:P25786 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-359352|uniprotkb:Q9BRV9|uniprotkb:A8K400|uniprotkb:Q53YE8|ensembl:ENSP00000379676 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:psa1_human(display_long)|uniprotkb:PSMA1(gene name)|psi-mi:PSMA1(display_short)|uniprotkb:PROS30(gene name synonym)|uniprotkb:PSC2(gene name synonym)|uniprotkb:Proteasome component C2(gene name synonym)|uniprotkb:Macropain subunit C2(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C2(gene name synonym)|uniprotkb:Proteasome nu chain(gene name synonym)|uniprotkb:30 kDa prosomal protein(gene name synonym)|uniprotkb:HC2(gene name synonym)|uniprotkb:NU(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675904|imex:IM-22977-66 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_002777.1|refseq:NP_683877.1|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000129084(gene)|ensembl:ENST00000396394(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0003723"(RNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0005844"(polysome)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|mint:P25786|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|dip:DIP-29369N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:tAADzZ1G9E/0BBeS8vybNx97v7k9606 intact-crc:85694AA92D558925|rigid:G3NxB9GjJ3j72vMre9Ne9XlZ57c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:Q9NSA3 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-747082|ensembl:ENSP00000366466|ensembl:ENSP00000366468|ensembl:ENSP00000366474|ensembl:ENSP00000383696|uniprotkb:Q5T4V2 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:cnbp1_human(display_long)|uniprotkb:Inhibitor of beta-catenin and Tcf-4(gene name synonym)|uniprotkb:CTNNBIP1(gene name)|psi-mi:CTNNBIP1(display_short)|uniprotkb:ICAT(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675909|imex:IM-22977-67 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_001012329.1|refseq:NP_064633.1|ensembl:ENSG00000178585(gene)|ensembl:ENST00000377256(transcript)|ensembl:ENST00000377258(transcript)|ensembl:ENST00000377263(transcript)|ensembl:ENST00000400904(transcript)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0002528"(regulation of vascular permeability involved in acute inflammatory response)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0060633"(negative regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0072201"(negative regulation of mesenchymal cell proliferation)|interpro:IPR009428(Beta-catenin-interacting ICAT)|interpro:IPR036911|interpro:IPR042999|rcsb pdb:1LUJ|rcsb pdb:1M1E|rcsb pdb:1T08|reactome:R-HSA-3769402|refseq:XP_016857342.1|refseq:XP_016857343.1|refseq:XP_016857344.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:+u/qGVFIboIBdcxthYr2OA1US3w9606 intact-crc:B655772F6FC89F83|rigid:nMufRz+/oZeA/YhH5H5XJk5Zlyg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A8K1J0 uniprotkb:P14079 intact:EBI-9675917 intact:EBI-9675698|uniprotkb:O56231 psi-mi:a8k1j0_human(display_long) psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675914|imex:IM-22977-68 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR035175 interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:vDMi5ExMRZu+QfhPYYmxG+0DwB09606 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 intact-crc:AADA3892D0B4FAF3|rigid:a0hKMu4AEvDtrDWELOlxh0WbWnc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:Q15654 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675963|imex:IM-22977-74 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606 intact-crc:A40DBAA5EFFF8DCC|rigid:lqhLuQdZeyGZbvvv9o2VSccp+Tk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:P82932 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-716172|uniprotkb:Q96Q64|uniprotkb:Q9BSK8|uniprotkb:Q9BW89|uniprotkb:B2R573|ensembl:ENSP00000382250 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:rt06_human(display_long)|uniprotkb:MRPS6(gene name)|psi-mi:MRPS6(display_short)|uniprotkb:C21orf101(gene name synonym)|uniprotkb:RPMS6(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein bS6m(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675958|imex:IM-22977-73 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_115865.1|ensembl:ENSG00000243927(gene)|ensembl:ENST00000399312(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR000529(Ribosomal protein S6)|interpro:IPR014717(Translation elongation factor EF1B/ribosomal protein S6)|interpro:IPR035980|mint:P82932|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZSA|rcsb pdb:6ZS9|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:mMPTr45GZxT1pj2RBZvvG6TrQmo9606 intact-crc:1F60C0ABA30C845A|rigid:i3xXdNaXW0JVBwMoWJJckFbZ+IQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5W5X9 uniprotkb:P14079 intact:EBI-6447954|ensembl:ENSP00000377690|ensembl:ENSP00000377692|ensembl:ENSP00000452923|uniprotkb:A8K6M5|uniprotkb:Q96BC9|uniprotkb:Q53HK0|uniprotkb:Q9H9S7|uniprotkb:Q9H8W9 intact:EBI-9675698|uniprotkb:O56231 psi-mi:ttc23_human(display_long)|uniprotkb:Cervical cancer proto-oncogene 8 protein(gene name synonym)|uniprotkb:HCC8(orf name)|uniprotkb:TTC23(gene name)|psi-mi:TTC23(display_short) psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675953|imex:IM-22977-72 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016878001.1|refseq:XP_016878002.1|refseq:XP_016878003.1|refseq:XP_016878004.1|refseq:XP_016878005.1|refseq:XP_016878006.1|refseq:XP_016878007.1|ensembl:ENSG00000103852(gene)|ensembl:ENST00000394132(transcript)|ensembl:ENST00000394135(transcript)|ensembl:ENST00000558663(transcript)|go:"GO:0005929"(cilium)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR042621|refseq:NP_001275544.1|refseq:NP_001275545.1 interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:9nX5a+iLJlIBNrWGL+LaB6HNUE09606 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 intact-crc:1BB0DA0BF537D176|rigid:0346ff2aCpwFg7R+95beF7F8+U8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:Q9HAQ2 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-8472129|intact:MINT-8417679|uniprotkb:Q9H8A4|uniprotkb:Q86Z28|ensembl:ENSP00000265529|ensembl:ENSP00000391100|ensembl:ENSP00000507186 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:kif9_human(display_long)|uniprotkb:KIF9(gene name)|psi-mi:KIF9(display_short) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675948|imex:IM-22977-71 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:XP_011532306.1|refseq:NP_071737.1|refseq:NP_001128350.1|refseq:NP_878905.2|refseq:XP_016862518.1|ensembl:ENSG00000088727(gene)|ensembl:ENST00000265529(transcript)|ensembl:ENST00000452770(transcript)|ensembl:ENST00000684063(transcript)|go:"GO:0002102"(podosome)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0031982"(vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0071801"(regulation of podosome assembly)|go:"GO:1903008"(organelle disassembly)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|mint:Q9HAQ2|rcsb pdb:3NWN|reactome:R-HSA-6811434|reactome:R-HSA-983189 psi-mi:"MI:0471"(mint) - comment:mint|comment:homomint figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:53+NnzzIaB0e+FlgTdFXGvetKtg9606 intact-crc:476C31E1A608DF9D|rigid:9zzXM0MEiWtUP/sfL4+DvggkpjE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:Q33E94 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-9675925|uniprotkb:Q33DW7|uniprotkb:Q8SNA1|uniprotkb:Q33E95|uniprotkb:Q8NDF9|uniprotkb:B2RDW4|uniprotkb:Q96S80|uniprotkb:Q6YM53|uniprotkb:A8K5Y0|uniprotkb:Q8NC78|uniprotkb:Q33DW6|uniprotkb:Q9BXI0|uniprotkb:Q8MHQ1|ensembl:ENSP00000376585 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:rfx4_human(display_long)|uniprotkb:RFX4(gene name)|psi-mi:RFX4(display_short)|uniprotkb:Regulatory factor X 4(gene name synonym)|uniprotkb:Testis development protein NYD-SP10(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675922|imex:IM-22977-69 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_001193620.1|refseq:NP_115880.2|refseq:NP_998759.1|ensembl:ENSG00000111783(gene)|ensembl:ENST00000392842(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0021537"(telencephalon development)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060271"(cilium assembly)|go:"GO:0070613"(regulation of protein processing)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003150(DNA-binding RFX)|interpro:IPR036388|interpro:IPR036390|interpro:IPR039779 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:O/qU4dSVZOwdQyCzqRqgouHNd6s9606 intact-crc:E5CAA51DD474A751|rigid:03tv8gQUXP/mF/ijK4sarQnvvao false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:Q9GZT8 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-740897|uniprotkb:Q9H2D2|uniprotkb:Q9HC18|uniprotkb:Q6X735|uniprotkb:Q53TX4|ensembl:ENSP00000386394|ensembl:ENSP00000387315|ensembl:ENSP00000498853 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:nif3l_human(display_long)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein(gene name synonym)|uniprotkb:MDS015(orf name)|uniprotkb:My018(orf name)|uniprotkb:NIF3L1(gene name)|psi-mi:NIF3L1(display_short)|uniprotkb:ALS2CR1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675943|imex:IM-22977-70 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_001129511.1|refseq:NP_001135827.1|refseq:NP_068596.2|refseq:XP_011509887.1|refseq:XP_011509884.1|refseq:XP_011509885.1|refseq:XP_011509886.1|refseq:NP_001135828.1|refseq:XP_005246799.1|refseq:XP_016860119.1|ensembl:ENSG00000196290(gene)|ensembl:ENST00000409020(transcript)|ensembl:ENST00000409357(transcript)|ensembl:ENST00000651500(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1903507"(negative regulation of nucleic acid-templated transcription)|interpro:IPR002678(NGG1p interacting factor 3, NIF3)|interpro:IPR017222(Uncharacterised conserved protein UCP037490, NIF3, eukaryota)|interpro:IPR036069|mint:Q9GZT8 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:Vvyb7CJpcwGtGAVKT2Zoqycr2yQ9606 intact-crc:F3E64EA0538C75BC|rigid:x17gWkhywLJG4lBfe0ESvGuhKis false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:Q6ZVK8 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-740486|intact:EBI-954151|ensembl:ENSP00000480722|uniprotkb:Q9H687|uniprotkb:Q8IZ75 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:nud18_human(display_long)|uniprotkb:NUDT18(gene name)|psi-mi:NUDT18(display_short)|uniprotkb:2-hydroxy-dADP phosphatase(gene name synonym)|uniprotkb:7,8-dihydro-8-oxoguanine phosphatase(gene name synonym)|uniprotkb:MTH3(gene name synonym)|uniprotkb:MutT homolog 3(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 18(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676001|imex:IM-22977-79 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_079091.3|ensembl:ENST00000611621(transcript)|ensembl:ENSG00000275074(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0044715"(8-oxo-dGDP phosphatase activity)|go:"GO:0044716"(8-oxo-GDP phosphatase activity)|go:"GO:0044717"(8-hydroxy-dADP phosphatase activity)|go:"GO:0046057"(dADP catabolic process)|go:"GO:0046067"(dGDP catabolic process)|go:"GO:0046712"(GDP catabolic process)|go:"GO:0055086"(nucleobase-containing small molecule metabolic process)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR020476|interpro:IPR042970|rcsb pdb:3GG6|rcsb pdb:4HVY|reactome:R-HSA-2393930 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:IBrXB2HhvhcyxMTQ0Xs5hGiimzA9606 intact-crc:10B064B124B6DB2C|rigid:iqmd6OEDYiB8xhFLBLx7NvQuFwc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8N883 uniprotkb:P14079 intact:EBI-9675993|uniprotkb:Q9BSN8|uniprotkb:Q8TCF4|uniprotkb:Q494T8|ensembl:ENSP00000270649 intact:EBI-9675698|uniprotkb:O56231 psi-mi:zn614_human(display_long)|uniprotkb:ZNF614(gene name)|psi-mi:ZNF614(display_short) psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675990|imex:IM-22977-78 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079316.2|ensembl:ENSG00000142556(gene)|ensembl:ENST00000270649(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436 interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:DTfWPcCHy/ZIwvALRCnGC6SMX749606 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 intact-crc:CA25A3AECFED7251|rigid:Hr2UBhwM50pqrX2T12B5CslJQTc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:Q6ZVK8 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-740486|intact:EBI-954151|ensembl:ENSP00000480722|uniprotkb:Q9H687|uniprotkb:Q8IZ75 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:nud18_human(display_long)|uniprotkb:NUDT18(gene name)|psi-mi:NUDT18(display_short)|uniprotkb:2-hydroxy-dADP phosphatase(gene name synonym)|uniprotkb:7,8-dihydro-8-oxoguanine phosphatase(gene name synonym)|uniprotkb:MTH3(gene name synonym)|uniprotkb:MutT homolog 3(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 18(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675985|imex:IM-22977-77 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_079091.3|ensembl:ENST00000611621(transcript)|ensembl:ENSG00000275074(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0044715"(8-oxo-dGDP phosphatase activity)|go:"GO:0044716"(8-oxo-GDP phosphatase activity)|go:"GO:0044717"(8-hydroxy-dADP phosphatase activity)|go:"GO:0046057"(dADP catabolic process)|go:"GO:0046067"(dGDP catabolic process)|go:"GO:0046712"(GDP catabolic process)|go:"GO:0055086"(nucleobase-containing small molecule metabolic process)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR020476|interpro:IPR042970|rcsb pdb:3GG6|rcsb pdb:4HVY|reactome:R-HSA-2393930 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:IBrXB2HhvhcyxMTQ0Xs5hGiimzA9606 intact-crc:68BC3D58335E2A62|rigid:iqmd6OEDYiB8xhFLBLx7NvQuFwc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BV90 uniprotkb:P14079 intact:EBI-9675976|uniprotkb:Q1W6H3|uniprotkb:Q6IEF8|uniprotkb:Q9H5W4|ensembl:ENSP00000372482 intact:EBI-9675698|uniprotkb:O56231 psi-mi:snr25_human(display_long)|uniprotkb:SNRNP25(gene name)|psi-mi:SNRNP25(display_short)|uniprotkb:C16orf33(gene name synonym)|uniprotkb:Minus-99 protein(gene name synonym) psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675973|imex:IM-22977-76 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078847.1|ensembl:ENSG00000161981(gene)|ensembl:ENST00000383018(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0045171"(intercellular bridge)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR039690|interpro:IPR040610|reactome:R-HSA-72165 interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:B7etUEbENf9LDAcnXK/Qy0rc4/k9606 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 intact-crc:C3CF8A10E08FF758|rigid:Hnorz5WAkw+fAt5QrEgcyLKO46w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:Q96BZ8 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-726510|uniprotkb:Q9HCU7|ensembl:ENSP00000222224|ensembl:ENSP00000477607|ensembl:ENSP00000478485|ensembl:ENSP00000479538|ensembl:ENSP00000480516|ensembl:ENSP00000481079|ensembl:ENSP00000481252|ensembl:ENSP00000481386|ensembl:ENSP00000481948|ensembl:ENSP00000483164 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:leng1_human(display_long)|uniprotkb:LENG1(gene name)|psi-mi:LENG1(display_short) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9675968|imex:IM-22977-75 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_077292.2|ensembl:ENSG00000105617(gene)|ensembl:ENSG00000275935(gene)|ensembl:ENSG00000276628(gene)|ensembl:ENSG00000276774(gene)|ensembl:ENSG00000277457(gene)|ensembl:ENSG00000277808(gene)|ensembl:ENSG00000278257(gene)|ensembl:ENSG00000278426(gene)|ensembl:ENSG00000278516(gene)|ensembl:ENST00000222224(transcript)|ensembl:ENST00000610998(transcript)|ensembl:ENST00000613622(transcript)|ensembl:ENST00000614037(transcript)|ensembl:ENST00000616103(transcript)|ensembl:ENST00000616816(transcript)|ensembl:ENST00000617592(transcript)|ensembl:ENST00000619669(transcript)|ensembl:ENST00000621285(transcript)|ensembl:ENST00000621927(transcript)|interpro:IPR019339|interpro:IPR039875|ensembl:ENSG00000276959(gene) psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:CbwywThJZ/wcqO76EMhiG8tvJN09606 intact-crc:32185BFEB0673F97|rigid:8MajMyBcnvMsy1teFd1rcCrz0RY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:Q96MT8 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-741977|uniprotkb:Q96CR0|uniprotkb:Q9H8F5|uniprotkb:Q9H8N0|uniprotkb:D3DND8|uniprotkb:D3DND9|uniprotkb:D3DNE0|ensembl:ENSP00000426129|ensembl:ENSP00000475903|ensembl:ENSP00000502085|ensembl:ENSP00000506896 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:cep63_human(display_long)|uniprotkb:CEP63(gene name)|psi-mi:CEP63(display_short) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676011|imex:IM-22977-81 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) go:"GO:0000922"(spindle pole)|go:"GO:0005829"(cytosol)|refseq:NP_001035842.1|refseq:NP_001035843.1|refseq:NP_001035859.1|refseq:NP_079456.2|ensembl:ENSG00000182923(gene)|ensembl:ENST00000513612(transcript)|ensembl:ENST00000606977(transcript)|ensembl:ENST00000675561(transcript)|ensembl:ENST00000683596(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005814"(centriole)|go:"GO:0005813"(centrosome)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|interpro:IPR029608|interpro:IPR031470|mint:Q96MT8|rcsb pdb:6CSU|rcsb pdb:6CSV|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|go:"GO:0007099"(centriole replication)|refseq:XP_011511496.1|refseq:XP_005247854.1|refseq:XP_006713823.1|refseq:XP_016862743.1|refseq:XP_016862744.1|refseq:XP_016862745.1|refseq:XP_016862751.1|refseq:XP_016862752.1|refseq:XP_016862753.1|refseq:XP_016862755.1|refseq:XP_016862756.1|dip:DIP-36374N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:/WPfint+sTGNCYCH9XG5rPYSOm09606 intact-crc:5CD4C5F6F7260E38|rigid:m33nyxKJYvhOb1y+xLbuKM7yhcY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:Q96MT8 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-741977|uniprotkb:Q96CR0|uniprotkb:Q9H8F5|uniprotkb:Q9H8N0|uniprotkb:D3DND8|uniprotkb:D3DND9|uniprotkb:D3DNE0|ensembl:ENSP00000426129|ensembl:ENSP00000475903|ensembl:ENSP00000502085|ensembl:ENSP00000506896 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:cep63_human(display_long)|uniprotkb:CEP63(gene name)|psi-mi:CEP63(display_short) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676016|imex:IM-22977-82 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) go:"GO:0000922"(spindle pole)|go:"GO:0005829"(cytosol)|refseq:NP_001035842.1|refseq:NP_001035843.1|refseq:NP_001035859.1|refseq:NP_079456.2|ensembl:ENSG00000182923(gene)|ensembl:ENST00000513612(transcript)|ensembl:ENST00000606977(transcript)|ensembl:ENST00000675561(transcript)|ensembl:ENST00000683596(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005814"(centriole)|go:"GO:0005813"(centrosome)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|interpro:IPR029608|interpro:IPR031470|mint:Q96MT8|rcsb pdb:6CSU|rcsb pdb:6CSV|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|go:"GO:0007099"(centriole replication)|refseq:XP_011511496.1|refseq:XP_005247854.1|refseq:XP_006713823.1|refseq:XP_016862743.1|refseq:XP_016862744.1|refseq:XP_016862745.1|refseq:XP_016862751.1|refseq:XP_016862752.1|refseq:XP_016862753.1|refseq:XP_016862755.1|refseq:XP_016862756.1|dip:DIP-36374N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:/WPfint+sTGNCYCH9XG5rPYSOm09606 intact-crc:24D89C1FE0CEFF76|rigid:m33nyxKJYvhOb1y+xLbuKM7yhcY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:Q5H9K5 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-2818620|uniprotkb:Q8NDS3|uniprotkb:Q96JN6|ensembl:ENSP00000361868|ensembl:ENSP00000437529 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:zmat1_human(display_long)|uniprotkb:ZMAT1(gene name)|psi-mi:ZMAT1(display_short)|uniprotkb:KIAA1789(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676026|imex:IM-22977-84 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) ensembl:ENSG00000166432(gene)|ensembl:ENST00000372782(transcript)|ensembl:ENST00000540921(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001269329.1|refseq:NP_001269330.1|refseq:XP_006724774.1|refseq:XP_016885393.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:hN4WqKioK0ZoOheB8rdh/4RaDX89606 intact-crc:1390090FEB729AB3|rigid:TEhoU2dHhpFQB5sa90IIuNI6Eoo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:Q9C086 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-715611|ensembl:ENSP00000233331 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:in80b_human(display_long)|uniprotkb:PAP-1-associated protein 1(gene name synonym)|uniprotkb:High mobility group AT-hook 1-like 4(gene name synonym)|uniprotkb:INO80B(gene name)|psi-mi:INO80B(display_short)|uniprotkb:HMGA1L4(gene name synonym)|uniprotkb:PAPA1(gene name synonym)|uniprotkb:ZNHIT4(gene name synonym)|uniprotkb:Zinc finger HIT domain-containing protein 4(gene name synonym)|uniprotkb:IES2 homolog(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676021|imex:IM-22977-83 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_112578.2|interpro:IPR029523|mint:Q9C086|rcsb pdb:6HTS|reactome:R-HSA-5689603|reactome:R-HSA-5696394|interpro:IPR007529(Zinc finger, HIT-type)|ensembl:ENSG00000115274(gene)|ensembl:ENST00000233331(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0031011"(Ino80 complex)|go:"GO:0043044"|go:"GO:0046872"(metal ion binding)|interpro:IPR006880(PAPA-1-like conserved region) psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:4nwc9Jv4wjrMHJTe7kMJt1Z0nks9606 intact-crc:B87BE3EF85BA7FE1|rigid:+93QJl5Q0Wu4Y8SsZ3KfP7gVGn4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:Q53HC0 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-719994|uniprotkb:Q9H697|uniprotkb:B3KNQ0|ensembl:ENSP00000238156|ensembl:ENSP00000488830 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:ccd92_human(display_long)|uniprotkb:Limkain beta-2(gene name synonym)|uniprotkb:CCDC92(gene name)|psi-mi:CCDC92(display_short) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676006|imex:IM-22977-80 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_079416.1|ensembl:ENSG00000119242(gene)|ensembl:ENSG00000275035(gene)|ensembl:ENST00000238156(transcript)|ensembl:ENST00000632401(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR033224|interpro:IPR039496|interpro:IPR040370|mint:Q53HC0|refseq:NP_001291886.1|refseq:NP_001291887.1|refseq:NP_001291888.1|refseq:NP_001291889.1|refseq:NP_001291890.1|refseq:XP_005253681.1|refseq:XP_016875473.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:Iu/FzTqEpzn8N5WUTt1OwoKWxyc9606 intact-crc:4E4D862ADC035DC0|rigid:6KI5X6DXx27+SUDj5xhWPc5/sKo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:O14964 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676061|imex:IM-22977-91 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606 intact-crc:CEFBCE4DCC6A275A|rigid:qUv1su1OTbVGQ03lScj/r5VT2Fw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:O14964 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676056|imex:IM-22977-90 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606 intact-crc:B6F797A4DB82D614|rigid:qUv1su1OTbVGQ03lScj/r5VT2Fw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:Q969F0 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-743099|ensembl:ENSP00000359375 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:fate1_human(display_long)|uniprotkb:Tumor antigen BJ-HCC-2(gene name synonym)|uniprotkb:Cancer/testis antigen 43(gene name synonym)|uniprotkb:FATE1(gene name)|psi-mi:FATE1(display_short)|uniprotkb:FATE(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676051|imex:IM-22977-89 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_149076.1|ensembl:ENSG00000147378(gene)|ensembl:ENST00000370350(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|interpro:IPR039153|interpro:IPR039433|mint:Q969F0 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:Nm1N6lO92MHr5rIKC007oouF5RE9606 intact-crc:829E9A554D55319F|rigid:nKr2+UEHSKF/5jctkdLdn5Zb5TI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:P78560 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-520375|uniprotkb:B7Z2Q5|ensembl:ENSP00000327647|ensembl:ENSP00000439068 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:cradd_human(display_long)|uniprotkb:Caspase and RIP adapter with death domain(gene name synonym)|uniprotkb:RIP-associated protein with a death domain(gene name synonym)|uniprotkb:CRADD(gene name)|psi-mi:CRADD(display_short)|uniprotkb:RAIDD(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676046|imex:IM-22977-88 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_003796.1|refseq:NP_001307029.1|refseq:NP_001307030.1|refseq:NP_001307028.1|refseq:XP_016875633.1|ensembl:ENSG00000169372(gene)|ensembl:ENST00000332896(transcript)|ensembl:ENST00000542893(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005829"(cytosol)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0070513"(death domain binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000488(Death)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR011029(DEATH-like)|interpro:IPR037926|interpro:IPR037939|interpro:IPR042148|mint:P78560|rcsb pdb:2O71|rcsb pdb:2OF5|rcsb pdb:3CRD|reactome:R-HSA-6803207|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm) psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:koYvv+L+23G4lMEFIFmYYBNaNkk9606 intact-crc:3DCA089F4D8F1783|rigid:0jPLmZ5kahwMuAt4JZAfGjEdWEs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:Q9UJX2 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-396137|uniprotkb:O75433|uniprotkb:Q9BS73|uniprotkb:B4E3A2|uniprotkb:B7WP05|uniprotkb:Q53FN2|uniprotkb:A8K6E5|uniprotkb:D3DQB7|ensembl:ENSP00000378350 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:cdc23_human(display_long)|uniprotkb:CDC23(gene name)|psi-mi:CDC23(display_short)|uniprotkb:ANAPC8(gene name synonym)|uniprotkb:Anaphase-promoting complex subunit 8(gene name synonym)|uniprotkb:Cyclosome subunit 8(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676041|imex:IM-22977-87 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_004652.2|dip:DIP-32959N|ensembl:ENSG00000094880(gene)|ensembl:ENST00000394886(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007091"(metaphase/anaphase transition of mitotic cell cycle)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR007192(Cdc23)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q9UJX2|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:uTZL2UHzZHLoKnio/1LcuSzZpW09606 intact-crc:C33D217C726EA33B|rigid:ZvYOFI3dBj0LUT2OupLzmgSVehQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:Q9BY27 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-742953|ensembl:ENSP00000248879|uniprotkb:Q9BW33|uniprotkb:A8K1N7|uniprotkb:D3DX29|uniprotkb:B3KMC0 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:dgc6l_human(display_long)|uniprotkb:DiGeorge syndrome critical region 6-like protein(gene name synonym)|uniprotkb:DGCR6L(gene name)|psi-mi:DGCR6L(display_short) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676036|imex:IM-22977-86 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) go:"GO:0005634"(nucleus)|interpro:IPR010849(DiGeorge syndrome critical 6)|ensembl:ENSG00000128185(gene)|ensembl:ENST00000248879(transcript)|refseq:NP_150282.2 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:kgKOLihCtc75qwW051IZsGLspI09606 intact-crc:B6C776005E0EA534|rigid:7ojyAekopTtJ6YR6b7+YYowkRyw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:Q8IUF8 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-751580|uniprotkb:Q6AHW4|uniprotkb:Q6SKS0|uniprotkb:Q8IU69|uniprotkb:Q8IUF6|uniprotkb:Q8IUF7|uniprotkb:Q96KB0|uniprotkb:Q96C17|uniprotkb:D3DN35|ensembl:ENSP00000328251|ensembl:ENSP00000377748 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:riox2_human(display_long)|uniprotkb:RIOX2(gene name)|psi-mi:RIOX2(display_short)|uniprotkb:60S ribosomal protein L27a histidine hydroxylase(gene name synonym)|uniprotkb:Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA(gene name synonym)|uniprotkb:Histone lysine demethylase MINA(gene name synonym)|uniprotkb:MDIG(gene name synonym)|uniprotkb:MINA(gene name synonym)|uniprotkb:MINA53(gene name synonym)|uniprotkb:MYC-induced nuclear antigen(gene name synonym)|uniprotkb:Mineral dust-induced gene protein(gene name synonym)|uniprotkb:NO52(gene name synonym)|uniprotkb:Nucleolar protein 52(gene name synonym)|uniprotkb:Ribosomal oxygenase MINA(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676031|imex:IM-22977-85 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_001035998.1|refseq:NP_116167.3|refseq:NP_694822.2|refseq:NP_001248758.1|refseq:XP_005247895.1|dip:DIP-28141N|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR039994|mint:Q8IUF8|rcsb pdb:2XDV|rcsb pdb:4BU2|rcsb pdb:4BXF|reactome:R-HSA-3214842|ensembl:ENSG00000170854(gene)|ensembl:ENST00000333396(transcript)|ensembl:ENST00000394198(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity) psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:tdjUsv9EuHn+AADASjfGu9U15Xc9606 intact-crc:25298C3F307DAB65|rigid:V1d91icJHWkGK6GKOkVnGzvpqh4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03346 uniprotkb:Q9UBB9 intact:EBI-9676099 intact:EBI-1105213|uniprotkb:O95908|uniprotkb:Q5H8V8|uniprotkb:Q9UGV7|uniprotkb:Q9Y2Q8|ensembl:ENSP00000383892|ensembl:ENSP00000384297|ensembl:ENSP00000384421|ensembl:ENSP00000480171|ensembl:ENSP00000385861|uniprotkb:Q20WL0 psi-mi:gag_htlv2(display_long)|uniprotkb:gag(gene name)|psi-mi:gag(display_short)|uniprotkb:Pr53Gag(gene name synonym) psi-mi:tfp11_human(display_long)|uniprotkb:TFIP11(gene name)|psi-mi:TFIP11(display_short)|uniprotkb:HSPC006(orf name)|uniprotkb:STIP(gene name synonym)|uniprotkb:Septin and tuftelin-interacting protein 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676110|imex:IM-22977-97 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR003139(Delta-retroviral matrix, N-terminal)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010999(Retroviral matrix, N-terminal)|rcsb pdb:1JVR|refseq:NP_041002.1|interpro:IPR036875|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016032"(viral process)|go:"GO:0019013"(viral nucleocapsid) ensembl:ENSG00000100109(gene)|refseq:NP_001008697.1|refseq:NP_036275.1|go:"GO:0016607"(nuclear speck)|ensembl:ENST00000405938(transcript)|ensembl:ENST00000407148(transcript)|ensembl:ENST00000407431(transcript)|ensembl:ENST00000407690(transcript)|ensembl:ENST00000619735(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|interpro:IPR022159|interpro:IPR022783|interpro:IPR024933|mint:Q9UBB9|reactome:R-HSA-72163|refseq:XP_011528381.1|refseq:XP_016884224.1|refseq:NP_001333786.1|refseq:NP_001333787.1|refseq:NP_001333788.1|refseq:NP_001333790.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:i0OVEZNGSX2eXoKpHd0xWBzfWA811909 rogid:Brk0v9dAoy5ntoJVHFsvt+FFE3g9606 intact-crc:9C75C374C75FEABE|rigid:Z1l1AXVohJDtdcE7g1WLblUFJSU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03346 uniprotkb:Q8N448 intact:EBI-9676099 intact:EBI-2340947|uniprotkb:Q6ZMH2|uniprotkb:Q5W0P0|uniprotkb:Q96SH4|ensembl:ENSP00000325929|ensembl:ENSP00000497224 psi-mi:gag_htlv2(display_long)|uniprotkb:gag(gene name)|psi-mi:gag(display_short)|uniprotkb:Pr53Gag(gene name synonym) psi-mi:lnx2_human(display_long)|uniprotkb:LNX2(gene name)|psi-mi:LNX2(display_short)|uniprotkb:PDZRN1(gene name synonym)|uniprotkb:Numb-binding protein 2(gene name synonym)|uniprotkb:PDZ domain-containing RING finger protein 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676105|imex:IM-22977-96 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR003139(Delta-retroviral matrix, N-terminal)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010999(Retroviral matrix, N-terminal)|rcsb pdb:1JVR|refseq:NP_041002.1|interpro:IPR036875|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016032"(viral process)|go:"GO:0019013"(viral nucleocapsid) refseq:NP_699202.1|refseq:XP_016875923.1|ensembl:ENSG00000139517(gene)|ensembl:ENST00000316334(transcript)|ensembl:ENST00000649248(transcript)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036034|mint:Q8N448|rcsb pdb:2VWR|rcsb pdb:5DIN|rcsb pdb:5E11|rcsb pdb:5E1Y|rcsb pdb:5E21|rcsb pdb:5E22 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:i0OVEZNGSX2eXoKpHd0xWBzfWA811909 rogid:cIS5t4XkbnIgelDlUc692nI285g9606 intact-crc:ED3C5467A7FF4271|rigid:RKfWd06J0TbiNw54SvcYCPRypbA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03346 uniprotkb:Q07687 intact:EBI-9676099 intact:EBI-3908234|intact:EBI-28987231|ensembl:ENSP00000234198|uniprotkb:B4DMK4|uniprotkb:B7ZA14 psi-mi:gag_htlv2(display_long)|uniprotkb:gag(gene name)|psi-mi:gag(display_short)|uniprotkb:Pr53Gag(gene name synonym) psi-mi:dlx2_human(display_long)|uniprotkb:DLX2(gene name)|psi-mi:DLX2(display_short) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676096|imex:IM-22977-95 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR003139(Delta-retroviral matrix, N-terminal)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010999(Retroviral matrix, N-terminal)|rcsb pdb:1JVR|refseq:NP_041002.1|interpro:IPR036875|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016032"(viral process)|go:"GO:0019013"(viral nucleocapsid) refseq:NP_004396.1|ensembl:ENSP00000234198|ensembl:ENST00000466293|ensembl:ENSP00000446904|ensembl:ENSG00000115844(gene)|ensembl:ENST00000234198(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0021544"(subpallium development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021893"(cerebral cortex GABAergic interneuron fate commitment)|go:"GO:0030154"(cell differentiation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0048755"(branching morphogenesis of a nerve)|go:"GO:0051216"(cartilage development)|go:"GO:1902871"(positive regulation of amacrine cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR022135 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:i0OVEZNGSX2eXoKpHd0xWBzfWA811909 rogid:q2XVmJGOg+QrKEqqAYvC5LqS4ag9606 intact-crc:9D8D7408FE5DA6B2|rigid:dEei1iB26OAEtxEd+jMWN88DK8I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03383 uniprotkb:O43513 intact:EBI-9676086|uniprotkb:P03382 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 psi-mi:env_htlv2(display_long)|uniprotkb:env(gene name)|psi-mi:env(display_short)|uniprotkb:Env polyprotein(gene name synonym) psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676091|imex:IM-22977-94 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018154|refseq:NP_041006.1|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0055036"(virion membrane)|go:"GO:0019031"(viral envelope) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:iX64ZtD99Z1yVZ7DOWVSdgLJaTY11909 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 intact-crc:1F65F1047EB89DB6|rigid:dKvxa1OWsn5X9j4gdjbP/hruQ98 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:Q92546 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-2823702|uniprotkb:Q5TCV5|ensembl:ENSP00000367318 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:rgp1_human(display_long)|uniprotkb:RGP1(gene name)|psi-mi:RGP1(display_short)|uniprotkb:Retrograde Golgi transport protein RGP1 homolog(gene name synonym)|uniprotkb:KIAA0258(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676080|imex:IM-22977-93 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_001073965.2|ensembl:ENSG00000107185(gene)|ensembl:ENST00000378078(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034066"(Ric1-Rgp1 guanyl-nucleotide exchange factor complex)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:1903363"(negative regulation of cellular protein catabolic process)|interpro:IPR014848(Rgp1)|reactome:R-HSA-6811438|reactome:R-HSA-6811440|reactome:R-HSA-8876198 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:1clc9Psb0xKDstfEkTk/dxivDfM9606 intact-crc:B6A83C556B4AA345|rigid:iYxKJA+9erFJAczH6Mw/xQcZmE4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7L2R6 uniprotkb:P14079 intact:EBI-9676069|uniprotkb:A8MYG0|uniprotkb:B9EIL1|uniprotkb:Q9BV49|uniprotkb:B7ZAI5|uniprotkb:B4DF18|ensembl:ENSP00000379689 intact:EBI-9675698|uniprotkb:O56231 psi-mi:zn765_human(display_long)|uniprotkb:ZNF765(gene name)|psi-mi:ZNF765(display_short) psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676066|imex:IM-22977-92 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035275.1|ensembl:ENSG00000196417(gene)|ensembl:ENST00000396408(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236 interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:MS5zXNA3eHIBbkf6TPiX+bwOw8Q9606 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 intact-crc:0D35635CC30B9323|rigid:to1aqlkw9mugzsQ2vm6AyUUZZzY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03346 uniprotkb:Q53G59 intact:EBI-9676099 intact:EBI-740929|ensembl:ENSP00000356230|uniprotkb:A6NEN8|uniprotkb:B7Z7B8|uniprotkb:Q9HBX5 psi-mi:gag_htlv2(display_long)|uniprotkb:gag(gene name)|psi-mi:gag(display_short)|uniprotkb:Pr53Gag(gene name synonym) psi-mi:klh12_human(display_long)|uniprotkb:CUL3-interacting protein 1(gene name synonym)|uniprotkb:KLHL12(gene name)|psi-mi:KLHL12(display_short)|uniprotkb:C3IP1(gene name synonym)|uniprotkb:DKIR homolog(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676120|imex:IM-22977-99 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR003139(Delta-retroviral matrix, N-terminal)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010999(Retroviral matrix, N-terminal)|rcsb pdb:1JVR|refseq:NP_041002.1|interpro:IPR036875|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016032"(viral process)|go:"GO:0019013"(viral nucleocapsid) go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048208"(COPII vesicle coating)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|mint:Q53G59|rcsb pdb:2VPJ|rcsb pdb:6TTK|rcsb pdb:6V7O|reactome:R-HSA-4641258|refseq:NP_067646.1|ensembl:ENSG00000117153(gene)|ensembl:ENST00000367261(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0034451"(centriolar satellite)|refseq:NP_001289980.1|refseq:NP_001290038.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:i0OVEZNGSX2eXoKpHd0xWBzfWA811909 rogid:C4I/Ys9vqNqfG61HsXRZhywP4vE9606 intact-crc:00D61B089D7F7EE1|rigid:M7/EYGZGlFdLeyS35Ijja14hzhA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03346 uniprotkb:Q719H9 intact:EBI-9676099 intact:EBI-9027502|uniprotkb:A8K1F5|ensembl:ENSP00000314831|ensembl:ENSP00000384367|ensembl:ENSP00000408405|ensembl:ENSP00000464170 psi-mi:gag_htlv2(display_long)|uniprotkb:gag(gene name)|psi-mi:gag(display_short)|uniprotkb:Pr53Gag(gene name synonym) psi-mi:kctd1_human(display_long)|uniprotkb:KCTD1(gene name)|psi-mi:KCTD1(display_short)|uniprotkb:C18orf5(gene name synonym)|uniprotkb:Potassium channel tetramerization domain-containing protein 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676115|imex:IM-22977-98 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR003139(Delta-retroviral matrix, N-terminal)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010999(Retroviral matrix, N-terminal)|rcsb pdb:1JVR|refseq:NP_041002.1|interpro:IPR036875|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016032"(viral process)|go:"GO:0019013"(viral nucleocapsid) refseq:XP_016881197.1|refseq:NP_001129677.1|refseq:NP_001136202.1|refseq:NP_001245150.1|refseq:NP_945342.1|ensembl:ENSG00000134504(gene)|ensembl:ENST00000317932(transcript)|ensembl:ENST00000408011(transcript)|ensembl:ENST00000417602(transcript)|ensembl:ENST00000579973(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR011333(BTB/POZ fold)|mint:Q719H9|rcsb pdb:5BXB|rcsb pdb:5BXD|rcsb pdb:6S4L|reactome:R-HSA-8866904 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:i0OVEZNGSX2eXoKpHd0xWBzfWA811909 rogid:mv4g8/+TuoNkCitdTYpsxJH52I09606 intact-crc:A5C945152A100D93|rigid:tbFcYZQ8I+hupGNp+x7aITO7E2E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03363 uniprotkb:P19012 intact:EBI-9676133 intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546 psi-mi:pol_htlv2(display_long)|uniprotkb:gag-pro-pol(gene name)|psi-mi:gag-pro-pol(display_short)|uniprotkb:Pr160Gag-Pro-Pol(gene name synonym) psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676155|imex:IM-22977-105 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001037(Integrase, C-terminal, retroviral)|interpro:IPR001584(Integrase, catalytic core)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR001995(Peptidase A2A, retrovirus, catalytic)|interpro:IPR002156(Ribonuclease H)|interpro:IPR003139(Delta-retroviral matrix, N-terminal)|interpro:IPR003308(Integrase, N-terminal zinc-binding domain)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR018061|interpro:IPR021109|rcsb pdb:1JVR|refseq:NP_041003.3|interpro:IPR036397|interpro:IPR036862|interpro:IPR036875|rcsb pdb:6QBT|rcsb pdb:6QBV|rcsb pdb:6QBW|interpro:IPR043502|interpro:IPR043128|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0003964"(RNA-directed DNA polymerase activity)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015074"(DNA integration)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0044826"(viral genome integration into host DNA)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0075713"(establishment of integrated proviral latency) refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:3FlrPwlig4Db1uLRMaZz+1EKx7Q11909 rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606 intact-crc:B263E360ADA3FF8B|rigid:gm0TOhSxnVo1lYSZBmxJRMTbSQ4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03363 uniprotkb:Q9UBB9 intact:EBI-9676133 intact:EBI-1105213|uniprotkb:O95908|uniprotkb:Q5H8V8|uniprotkb:Q9UGV7|uniprotkb:Q9Y2Q8|ensembl:ENSP00000383892|ensembl:ENSP00000384297|ensembl:ENSP00000384421|ensembl:ENSP00000480171|ensembl:ENSP00000385861|uniprotkb:Q20WL0 psi-mi:pol_htlv2(display_long)|uniprotkb:gag-pro-pol(gene name)|psi-mi:gag-pro-pol(display_short)|uniprotkb:Pr160Gag-Pro-Pol(gene name synonym) psi-mi:tfp11_human(display_long)|uniprotkb:TFIP11(gene name)|psi-mi:TFIP11(display_short)|uniprotkb:HSPC006(orf name)|uniprotkb:STIP(gene name synonym)|uniprotkb:Septin and tuftelin-interacting protein 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676150|imex:IM-22977-104 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001037(Integrase, C-terminal, retroviral)|interpro:IPR001584(Integrase, catalytic core)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR001995(Peptidase A2A, retrovirus, catalytic)|interpro:IPR002156(Ribonuclease H)|interpro:IPR003139(Delta-retroviral matrix, N-terminal)|interpro:IPR003308(Integrase, N-terminal zinc-binding domain)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR018061|interpro:IPR021109|rcsb pdb:1JVR|refseq:NP_041003.3|interpro:IPR036397|interpro:IPR036862|interpro:IPR036875|rcsb pdb:6QBT|rcsb pdb:6QBV|rcsb pdb:6QBW|interpro:IPR043502|interpro:IPR043128|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0003964"(RNA-directed DNA polymerase activity)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015074"(DNA integration)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0044826"(viral genome integration into host DNA)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0075713"(establishment of integrated proviral latency) ensembl:ENSG00000100109(gene)|refseq:NP_001008697.1|refseq:NP_036275.1|go:"GO:0016607"(nuclear speck)|ensembl:ENST00000405938(transcript)|ensembl:ENST00000407148(transcript)|ensembl:ENST00000407431(transcript)|ensembl:ENST00000407690(transcript)|ensembl:ENST00000619735(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|interpro:IPR022159|interpro:IPR022783|interpro:IPR024933|mint:Q9UBB9|reactome:R-HSA-72163|refseq:XP_011528381.1|refseq:XP_016884224.1|refseq:NP_001333786.1|refseq:NP_001333787.1|refseq:NP_001333788.1|refseq:NP_001333790.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:3FlrPwlig4Db1uLRMaZz+1EKx7Q11909 rogid:Brk0v9dAoy5ntoJVHFsvt+FFE3g9606 intact-crc:9C745567055FEABE|rigid:7K845N6JcSpmfSABMb0bHemXljE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03363 uniprotkb:Q6P597 intact:EBI-9676133 intact:EBI-1643885|uniprotkb:Q6GMU2|uniprotkb:Q8NAL1|uniprotkb:Q8WWJ9|uniprotkb:A0AVM3|uniprotkb:A2RUT6|ensembl:ENSP00000375810 psi-mi:pol_htlv2(display_long)|uniprotkb:gag-pro-pol(gene name)|psi-mi:gag-pro-pol(display_short)|uniprotkb:Pr160Gag-Pro-Pol(gene name synonym) psi-mi:klc3_human(display_long)|uniprotkb:KLC3(gene name)|psi-mi:KLC3(display_short)|uniprotkb:KLC2(gene name synonym)|uniprotkb:KLC2L(gene name synonym)|uniprotkb:kinesin light chain 2(gene name synonym)|uniprotkb:KLC2-like(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676145|imex:IM-22977-103 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001037(Integrase, C-terminal, retroviral)|interpro:IPR001584(Integrase, catalytic core)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR001995(Peptidase A2A, retrovirus, catalytic)|interpro:IPR002156(Ribonuclease H)|interpro:IPR003139(Delta-retroviral matrix, N-terminal)|interpro:IPR003308(Integrase, N-terminal zinc-binding domain)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR018061|interpro:IPR021109|rcsb pdb:1JVR|refseq:NP_041003.3|interpro:IPR036397|interpro:IPR036862|interpro:IPR036875|rcsb pdb:6QBT|rcsb pdb:6QBV|rcsb pdb:6QBW|interpro:IPR043502|interpro:IPR043128|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0003964"(RNA-directed DNA polymerase activity)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015074"(DNA integration)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0044826"(viral genome integration into host DNA)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0075713"(establishment of integrated proviral latency) refseq:NP_803136.2|ensembl:ENSG00000104892(gene)|ensembl:ENST00000391946(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0031514"(motile cilium)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043005"(neuron projection)|interpro:IPR002151(Kinesin light chain)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q6P597|reactome:R-HSA-2132295|reactome:R-HSA-5625970|reactome:R-HSA-6811434|reactome:R-HSA-983189 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:3FlrPwlig4Db1uLRMaZz+1EKx7Q11909 rogid:nFc6MpOU6+ge5OJRjn3XIM/q02g9606 intact-crc:2D4C63B66F8496D6|rigid:5GaLt2GgC+5sh7zp/rsgcxCBDgQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03363 uniprotkb:Q93062 intact:EBI-9676133 intact:EBI-740322|uniprotkb:Q92516|uniprotkb:Q92517|uniprotkb:Q92518|uniprotkb:Q96J26|uniprotkb:D3DSU9|ensembl:ENSP00000318102|ensembl:ENSP00000380486 psi-mi:pol_htlv2(display_long)|uniprotkb:gag-pro-pol(gene name)|psi-mi:gag-pro-pol(display_short)|uniprotkb:Pr160Gag-Pro-Pol(gene name synonym) psi-mi:rbpms_human(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676140|imex:IM-22977-102 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001037(Integrase, C-terminal, retroviral)|interpro:IPR001584(Integrase, catalytic core)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR001995(Peptidase A2A, retrovirus, catalytic)|interpro:IPR002156(Ribonuclease H)|interpro:IPR003139(Delta-retroviral matrix, N-terminal)|interpro:IPR003308(Integrase, N-terminal zinc-binding domain)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR018061|interpro:IPR021109|rcsb pdb:1JVR|refseq:NP_041003.3|interpro:IPR036397|interpro:IPR036862|interpro:IPR036875|rcsb pdb:6QBT|rcsb pdb:6QBV|rcsb pdb:6QBW|interpro:IPR043502|interpro:IPR043128|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0003964"(RNA-directed DNA polymerase activity)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015074"(DNA integration)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0044826"(viral genome integration into host DNA)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0075713"(establishment of integrated proviral latency) refseq:NP_001008710.1|refseq:NP_001008711.1|refseq:NP_001008712.1|refseq:NP_006858.1|ensembl:ENSG00000157110(gene)|ensembl:ENST00000320203(transcript)|ensembl:ENST00000397323(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008143"("poly(A) binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:Q93062|rcsb pdb:1BNY|rcsb pdb:5CYJ|rcsb pdb:5DET|refseq:XP_016868475.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:3FlrPwlig4Db1uLRMaZz+1EKx7Q11909 rogid:3PsLJDzqs+19eVFeQlN+yLielYM9606 intact-crc:98B1E1FA856B51AD|rigid:v0K+83AxnpIHlS2NiZT6s5OmyoI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03363 uniprotkb:O60504 intact:EBI-9676133 intact:EBI-741237|ensembl:ENSP00000240123|uniprotkb:Q5BJE4|uniprotkb:Q6NX54|uniprotkb:Q9UQE4|intact:EBI-1222937|uniprotkb:Q96FY4 psi-mi:pol_htlv2(display_long)|uniprotkb:gag-pro-pol(gene name)|psi-mi:gag-pro-pol(display_short)|uniprotkb:Pr160Gag-Pro-Pol(gene name synonym) psi-mi:vinex_human(display_long)|uniprotkb:SCAM1(gene name synonym)|uniprotkb:SH3-containing adapter molecule 1(gene name synonym)|uniprotkb:Sorbin and SH3 domain-containing protein 3(gene name synonym)|uniprotkb:SORBS3(gene name)|psi-mi:SORBS3(display_short) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676130|imex:IM-22977-101 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001037(Integrase, C-terminal, retroviral)|interpro:IPR001584(Integrase, catalytic core)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR001995(Peptidase A2A, retrovirus, catalytic)|interpro:IPR002156(Ribonuclease H)|interpro:IPR003139(Delta-retroviral matrix, N-terminal)|interpro:IPR003308(Integrase, N-terminal zinc-binding domain)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR018061|interpro:IPR021109|rcsb pdb:1JVR|refseq:NP_041003.3|interpro:IPR036397|interpro:IPR036862|interpro:IPR036875|rcsb pdb:6QBT|rcsb pdb:6QBV|rcsb pdb:6QBW|interpro:IPR043502|interpro:IPR043128|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0003964"(RNA-directed DNA polymerase activity)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015074"(DNA integration)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0044826"(viral genome integration into host DNA)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0075713"(establishment of integrated proviral latency) ensembl:ENSG00000120896(gene)|ensembl:ENST00000240123(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0017166"(vinculin binding)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0051495"(positive regulation of cytoskeleton organization)|go:"GO:0051496"(positive regulation of stress fiber assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR028510|interpro:IPR035607|interpro:IPR035608|interpro:IPR035609|interpro:IPR036028|mint:O60504|rcsb pdb:2CT3|rcsb pdb:2DLM|rcsb pdb:2NWM|rcsb pdb:2YUP|reactome:R-HSA-445355|refseq:NP_001018003.1|refseq:NP_005766.3|refseq:XP_005273428.1|refseq:XP_016868433.1|refseq:XP_016868434.1|refseq:XP_016868435.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:3FlrPwlig4Db1uLRMaZz+1EKx7Q11909 rogid:Mq3VXduU/1gqfUwliO9sBBOb/Vc9606 intact-crc:7581F7EB8DEA4B97|rigid:doB3pKJ/BZrFvmhHJRI+e9eC1cI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03346 uniprotkb:Q12933 intact:EBI-9676099 intact:EBI-355744|uniprotkb:Q96NT2|uniprotkb:A8K107|uniprotkb:B4DPJ7|uniprotkb:Q7Z337|intact:EBI-1046651|ensembl:ENSP00000247668 psi-mi:gag_htlv2(display_long)|uniprotkb:gag(gene name)|psi-mi:gag(display_short)|uniprotkb:Pr53Gag(gene name synonym) psi-mi:traf2_human(display_long)|uniprotkb:TRAF2(gene name)|psi-mi:TRAF2(display_short)|uniprotkb:TRAP3(gene name synonym)|uniprotkb:Tumor necrosis factor type 2 receptor-associated protein 3(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRAF2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676125|imex:IM-22977-100 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR003139(Delta-retroviral matrix, N-terminal)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010999(Retroviral matrix, N-terminal)|rcsb pdb:1JVR|refseq:NP_041002.1|interpro:IPR036875|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016032"(viral process)|go:"GO:0019013"(viral nucleocapsid) refseq:NP_066961.2|refseq:XP_011517279.1|refseq:XP_011517280.1|refseq:XP_011517276.1|refseq:XP_011517277.1|refseq:XP_011517278.1|ensembl:ENSG00000127191(gene)|ensembl:ENST00000247668(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002947"(tumor necrosis factor receptor superfamily complex)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0097057"(TRAF2-GSTP1 complex)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990604"(IRE1-TRAF2-ASK1 complex)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005174"(CD40 receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034351"(negative regulation of glial cell apoptotic process)|go:"GO:0034622"|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043120"(tumor necrosis factor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027133|interpro:IPR032070|interpro:IPR037305|interpro:IPR043211|mint:Q12933|rcsb pdb:1CA4|rcsb pdb:1CA9|rcsb pdb:1CZY|rcsb pdb:1CZZ|rcsb pdb:1D00|rcsb pdb:1D01|rcsb pdb:1D0A|rcsb pdb:1D0J|rcsb pdb:1F3V|rcsb pdb:1QSC|rcsb pdb:3KNV|rcsb pdb:3M06|rcsb pdb:3M0A|rcsb pdb:3M0D|reactome:R-HSA-140534|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5668541|reactome:R-HSA-5675482|reactome:R-HSA-5676594|reactome:R-HSA-5689880|reactome:R-HSA-69416|reactome:R-HSA-75893|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-9693928|refseq:XP_016870584.1|dip:DIP-6223N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:i0OVEZNGSX2eXoKpHd0xWBzfWA811909 rogid:JhaoM5kRLh3zwhXr+BsCCRNOYa09606 intact-crc:479E3EA848A8F009|rigid:NXUiqS4ErQ+lr6AUlL0x7CdrCRs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q85601 uniprotkb:Q8N448 intact:EBI-9676175 intact:EBI-2340947|uniprotkb:Q6ZMH2|uniprotkb:Q5W0P0|uniprotkb:Q96SH4|ensembl:ENSP00000325929|ensembl:ENSP00000497224 psi-mi:rex_htlv2(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-2(gene name synonym) psi-mi:lnx2_human(display_long)|uniprotkb:LNX2(gene name)|psi-mi:LNX2(display_short)|uniprotkb:PDZRN1(gene name synonym)|uniprotkb:Numb-binding protein 2(gene name synonym)|uniprotkb:PDZ domain-containing RING finger protein 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676193|imex:IM-22977-112 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041004.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) refseq:NP_699202.1|refseq:XP_016875923.1|ensembl:ENSG00000139517(gene)|ensembl:ENST00000316334(transcript)|ensembl:ENST00000649248(transcript)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036034|mint:Q8N448|rcsb pdb:2VWR|rcsb pdb:5DIN|rcsb pdb:5E11|rcsb pdb:5E1Y|rcsb pdb:5E21|rcsb pdb:5E22 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:JALmnTn2BuPjeDXSyA8raxDgM0411909 rogid:cIS5t4XkbnIgelDlUc692nI285g9606 intact-crc:CE816C45A3EA2E4C|rigid:AvVh3MEdbHmiEfuktF2hClh3on8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q85601 uniprotkb:Q8N448 intact:EBI-9676175 intact:EBI-2340947|uniprotkb:Q6ZMH2|uniprotkb:Q5W0P0|uniprotkb:Q96SH4|ensembl:ENSP00000325929|ensembl:ENSP00000497224 psi-mi:rex_htlv2(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-2(gene name synonym) psi-mi:lnx2_human(display_long)|uniprotkb:LNX2(gene name)|psi-mi:LNX2(display_short)|uniprotkb:PDZRN1(gene name synonym)|uniprotkb:Numb-binding protein 2(gene name synonym)|uniprotkb:PDZ domain-containing RING finger protein 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676188|imex:IM-22977-111 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041004.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) refseq:NP_699202.1|refseq:XP_016875923.1|ensembl:ENSG00000139517(gene)|ensembl:ENST00000316334(transcript)|ensembl:ENST00000649248(transcript)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036034|mint:Q8N448|rcsb pdb:2VWR|rcsb pdb:5DIN|rcsb pdb:5E11|rcsb pdb:5E1Y|rcsb pdb:5E21|rcsb pdb:5E22 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:JALmnTn2BuPjeDXSyA8raxDgM0411909 rogid:cIS5t4XkbnIgelDlUc692nI285g9606 intact-crc:B68D35ACB402DF02|rigid:AvVh3MEdbHmiEfuktF2hClh3on8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q85601 uniprotkb:Q96FJ2 intact:EBI-9676175 intact:EBI-742371|uniprotkb:B2R5B4|ensembl:ENSP00000477310 psi-mi:rex_htlv2(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-2(gene name synonym) psi-mi:dyl2_human(display_long)|uniprotkb:DYNLL2(gene name)|psi-mi:DYNLL2(display_short)|uniprotkb:Dynein light chain LC8-type 2(gene name synonym)|uniprotkb:DLC2(gene name synonym)|uniprotkb:8 kDa dynein light chain b(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676183|imex:IM-22977-110 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041004.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) go:"GO:0005813"(centrosome)|refseq:NP_542408.1|ensembl:ENSG00000264364(gene)|ensembl:ENST00000579991(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0007017"(microtubule-based process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0030286"(dynein complex)|go:"GO:0031475"(myosin V complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097542"(ciliary tip)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:Q96FJ2|rcsb pdb:2XQQ|rcsb pdb:3P8M|rcsb pdb:4D07|reactome:R-HSA-139910|reactome:R-HSA-141444|reactome:R-HSA-1632852|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-5620924|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:JALmnTn2BuPjeDXSyA8raxDgM0411909 rogid:4RFpJF40RBja5mOvt/aCv3miiDU9606 intact-crc:CCBEB0763C04F45F|rigid:0i6piXIDT5hPVHTIqdAcNyclymc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q85601 uniprotkb:O43186 intact:EBI-9676175 intact:EBI-748171|uniprotkb:Q0QD45|ensembl:ENSP00000221996|ensembl:ENSP00000445565 psi-mi:rex_htlv2(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-2(gene name synonym) psi-mi:crx_human(display_long)|uniprotkb:CRX(gene name)|psi-mi:CRX(display_short)|uniprotkb:CORD2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676178|imex:IM-22977-109 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041004.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) refseq:NP_000545.1|ensembl:ENSG00000105392(gene)|ensembl:ENST00000221996(transcript)|ensembl:ENST00000539067(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050896"(response to stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:JALmnTn2BuPjeDXSyA8raxDgM0411909 rogid:v/bkO/0iLzq1Q2HtieWQQ40RF9M9606 intact-crc:6DA9B98DD4E2F949|rigid:6EduZwIMoH/qbIZNQQgr9Typ3uo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03363 uniprotkb:Q13064 intact:EBI-9676133 intact:EBI-2340269|ensembl:ENSP00000313881 psi-mi:pol_htlv2(display_long)|uniprotkb:gag-pro-pol(gene name)|psi-mi:gag-pro-pol(display_short)|uniprotkb:Pr160Gag-Pro-Pol(gene name synonym) psi-mi:mkrn3_human(display_long)|uniprotkb:MKRN3(gene name)|psi-mi:MKRN3(display_short)|uniprotkb:D15S9(gene name synonym)|uniprotkb:RNF63(gene name synonym)|uniprotkb:ZNF127(gene name synonym)|uniprotkb:Zinc finger protein 127(gene name synonym)|uniprotkb:RING finger protein 63(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase makorin-3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676170|imex:IM-22977-108 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001037(Integrase, C-terminal, retroviral)|interpro:IPR001584(Integrase, catalytic core)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR001995(Peptidase A2A, retrovirus, catalytic)|interpro:IPR002156(Ribonuclease H)|interpro:IPR003139(Delta-retroviral matrix, N-terminal)|interpro:IPR003308(Integrase, N-terminal zinc-binding domain)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR018061|interpro:IPR021109|rcsb pdb:1JVR|refseq:NP_041003.3|interpro:IPR036397|interpro:IPR036862|interpro:IPR036875|rcsb pdb:6QBT|rcsb pdb:6QBV|rcsb pdb:6QBW|interpro:IPR043502|interpro:IPR043128|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0003964"(RNA-directed DNA polymerase activity)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015074"(DNA integration)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0044826"(viral genome integration into host DNA)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0075713"(establishment of integrated proviral latency) refseq:NP_005655.1|ensembl:ENSG00000179455(gene)|ensembl:ENST00000314520(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR026294|interpro:IPR031644|interpro:IPR036855|interpro:IPR041367|mint:Q13064 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:3FlrPwlig4Db1uLRMaZz+1EKx7Q11909 rogid:3sZzqtO8FoR/vVI64iFKb0iuuSc9606 intact-crc:9704C5FB17C8D5CA|rigid:BcA/TmkyVuQSsJZr2SYgKWYKVVE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03363 uniprotkb:Q8IYF3 intact:EBI-9676133 intact:EBI-742397|ensembl:ENSP00000340995|ensembl:ENSP00000379226|uniprotkb:Q5JQQ8|uniprotkb:Q96LZ4|uniprotkb:Q96M47|uniprotkb:Q9BXU6|uniprotkb:A8K8V6 psi-mi:pol_htlv2(display_long)|uniprotkb:gag-pro-pol(gene name)|psi-mi:gag-pro-pol(display_short)|uniprotkb:Pr160Gag-Pro-Pol(gene name synonym) psi-mi:tex11_human(display_long)|uniprotkb:TEX11(gene name)|psi-mi:TEX11(display_short)|uniprotkb:Protein ZIP4 homolog(gene name synonym)|uniprotkb:ZIP4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676165|imex:IM-22977-107 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001037(Integrase, C-terminal, retroviral)|interpro:IPR001584(Integrase, catalytic core)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR001995(Peptidase A2A, retrovirus, catalytic)|interpro:IPR002156(Ribonuclease H)|interpro:IPR003139(Delta-retroviral matrix, N-terminal)|interpro:IPR003308(Integrase, N-terminal zinc-binding domain)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR018061|interpro:IPR021109|rcsb pdb:1JVR|refseq:NP_041003.3|interpro:IPR036397|interpro:IPR036862|interpro:IPR036875|rcsb pdb:6QBT|rcsb pdb:6QBV|rcsb pdb:6QBW|interpro:IPR043502|interpro:IPR043128|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0003964"(RNA-directed DNA polymerase activity)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015074"(DNA integration)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0044826"(viral genome integration into host DNA)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0075713"(establishment of integrated proviral latency) ensembl:ENSG00000120498(gene)|ensembl:ENST00000344304(transcript)|ensembl:ENST00000395889(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000801"(central element)|go:"GO:0005694"(chromosome)|go:"GO:0006311"(meiotic gene conversion)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008584"(male gonad development)|go:"GO:0009566"(fertilization)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0051026"(chiasma assembly)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013940(Meiosis specific protein SPO22)|interpro:IPR019734|interpro:IPR042861|refseq:NP_001003811.1|refseq:NP_112566.2|refseq:XP_011529298.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:3FlrPwlig4Db1uLRMaZz+1EKx7Q11909 rogid:xzJnHUKkYr8TqYKI9wKTTwxgB+U9606 intact-crc:3EF782483FBA65F2|rigid:82zVBJEADNgPVr6TdMBh2NaSapo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03363 uniprotkb:O14770 intact:EBI-9676133 intact:EBI-2804934|uniprotkb:Q96KI5|uniprotkb:Q9NRS3|uniprotkb:Q9NRS1|uniprotkb:Q9NRS2|uniprotkb:Q96KI4|ensembl:ENSP00000453793|uniprotkb:A6NJI5|uniprotkb:A8MWD5|uniprotkb:B3KP98|uniprotkb:B3KPQ6|uniprotkb:Q96DI2 psi-mi:pol_htlv2(display_long)|uniprotkb:gag-pro-pol(gene name)|psi-mi:gag-pro-pol(display_short)|uniprotkb:Pr160Gag-Pro-Pol(gene name synonym) psi-mi:meis2_human(display_long)|uniprotkb:MRG1(gene name synonym)|uniprotkb:Meis1-related protein 1(gene name synonym)|uniprotkb:MEIS2(gene name)|psi-mi:MEIS2(display_short) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676160|imex:IM-22977-106 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001037(Integrase, C-terminal, retroviral)|interpro:IPR001584(Integrase, catalytic core)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR001995(Peptidase A2A, retrovirus, catalytic)|interpro:IPR002156(Ribonuclease H)|interpro:IPR003139(Delta-retroviral matrix, N-terminal)|interpro:IPR003308(Integrase, N-terminal zinc-binding domain)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR018061|interpro:IPR021109|rcsb pdb:1JVR|refseq:NP_041003.3|interpro:IPR036397|interpro:IPR036862|interpro:IPR036875|rcsb pdb:6QBT|rcsb pdb:6QBV|rcsb pdb:6QBW|interpro:IPR043502|interpro:IPR043128|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0003964"(RNA-directed DNA polymerase activity)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015074"(DNA integration)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0044826"(viral genome integration into host DNA)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0075713"(establishment of integrated proviral latency) ensembl:ENSG00000134138(gene)|ensembl:ENST00000561208(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008542"(visual learning)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0031016"(pancreas development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070848"(response to growth factor)|go:"GO:0110024"(positive regulation of cardiac muscle myoblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|mint:O14770|rcsb pdb:3K2A|rcsb pdb:4XRM|rcsb pdb:5BNG|rcsb pdb:5EG0|refseq:NP_001207411.1|refseq:NP_733774.1|refseq:NP_733775.1|refseq:NP_733776.1|refseq:NP_733777.1|refseq:NP_002390.1|refseq:NP_758526.1|refseq:NP_758527.1|ensembl:ENST00000314177|ensembl:ENSP00000326296|ensembl:ENST00000338564|ensembl:ENSP00000341400|ensembl:ENST00000340545|ensembl:ENSP00000339549|ensembl:ENST00000397620|ensembl:ENSP00000380745|ensembl:ENST00000397624|ensembl:ENSP00000380749|ensembl:ENST00000424352|ensembl:ENSP00000404185|ensembl:ENST00000557796|ensembl:ENSP00000452693|ensembl:ENST00000559085|ensembl:ENSP00000453390|ensembl:ENST00000559561|ensembl:ENSP00000453497|ensembl:ENSP00000453793|refseq:XP_016877694.1|dip:DIP-61027N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:3FlrPwlig4Db1uLRMaZz+1EKx7Q11909 rogid:dzZaH/NCkNWqc4N6ZVa+i5Knqrg9606 intact-crc:75801B0F5DC4AFB0|rigid:BmVi4jUnfGRwXUgrTPOQZ6IQu1o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:Q9Y2D8 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676224|imex:IM-22977-117 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606 intact-crc:F8E919D488AD9845|rigid:4yfIE9G9j3f1FHFEjsZvM0d9kys false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q85601 uniprotkb:P23497 intact:EBI-9676175 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 psi-mi:rex_htlv2(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-2(gene name synonym) psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676213|imex:IM-22977-116 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041004.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:JALmnTn2BuPjeDXSyA8raxDgM0411909 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 intact-crc:4939C2962306E702|rigid:lQlD/0PRD7YCsWn6bf4Xmfh04rE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q85601 uniprotkb:Q9GZT8 intact:EBI-9676175 intact:EBI-740897|uniprotkb:Q9H2D2|uniprotkb:Q9HC18|uniprotkb:Q6X735|uniprotkb:Q53TX4|ensembl:ENSP00000386394|ensembl:ENSP00000387315|ensembl:ENSP00000498853 psi-mi:rex_htlv2(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-2(gene name synonym) psi-mi:nif3l_human(display_long)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein(gene name synonym)|uniprotkb:MDS015(orf name)|uniprotkb:My018(orf name)|uniprotkb:NIF3L1(gene name)|psi-mi:NIF3L1(display_short)|uniprotkb:ALS2CR1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676208|imex:IM-22977-115 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041004.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) refseq:NP_001129511.1|refseq:NP_001135827.1|refseq:NP_068596.2|refseq:XP_011509887.1|refseq:XP_011509884.1|refseq:XP_011509885.1|refseq:XP_011509886.1|refseq:NP_001135828.1|refseq:XP_005246799.1|refseq:XP_016860119.1|ensembl:ENSG00000196290(gene)|ensembl:ENST00000409020(transcript)|ensembl:ENST00000409357(transcript)|ensembl:ENST00000651500(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1903507"(negative regulation of nucleic acid-templated transcription)|interpro:IPR002678(NGG1p interacting factor 3, NIF3)|interpro:IPR017222(Uncharacterised conserved protein UCP037490, NIF3, eukaryota)|interpro:IPR036069|mint:Q9GZT8 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:JALmnTn2BuPjeDXSyA8raxDgM0411909 rogid:Vvyb7CJpcwGtGAVKT2Zoqycr2yQ9606 intact-crc:A85594C96FB2B4AE|rigid:Eeg/kPnMrNcgtF3nawxkSuKXhr0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q85601 uniprotkb:Q9NZD8 intact:EBI-9676175 intact:EBI-742688|uniprotkb:B4DW44|uniprotkb:Q6ZMB6|ensembl:ENSP00000204566|ensembl:ENSP00000404111 psi-mi:rex_htlv2(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-2(gene name synonym) psi-mi:spg21_human(display_long)|uniprotkb:Spastic paraplegia 21 autosomal recessive Mast syndrome protein(gene name synonym)|uniprotkb:Acid cluster protein 33(gene name synonym)|uniprotkb:SPG21(gene name)|psi-mi:SPG21(display_short)|uniprotkb:ACP33(gene name synonym)|uniprotkb:BM-019(orf name)|uniprotkb:GL010(orf name)|uniprotkb:Spastic paraplegia 21 protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676203|imex:IM-22977-114 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041004.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) refseq:NP_001121361.1|refseq:NP_001121362.1|refseq:NP_057714.1|ensembl:ENSG00000090487(gene)|ensembl:ENST00000204566(transcript)|ensembl:ENST00000433215(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR026151|interpro:IPR029058|mint:Q9NZD8|refseq:XP_005254494.1|refseq:XP_016877786.1|refseq:XP_016877787.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:JALmnTn2BuPjeDXSyA8raxDgM0411909 rogid:MoKySBpEYFNm7Lox/HM5nnkmhkA9606 intact-crc:728B4FA5771699A1|rigid:PhBBRBQZ21r8tcNqA2YD7Ybt72Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q85601 uniprotkb:P37198 intact:EBI-9676175 intact:EBI-347978|intact:EBI-28983799|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|uniprotkb:Q6GTM2|uniprotkb:Q503A4|uniprotkb:Q96C43|uniprotkb:Q9NSL1|uniprotkb:B3KWU5 psi-mi:rex_htlv2(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-2(gene name synonym) psi-mi:nup62_human(display_long)|uniprotkb:NUP62(gene name)|psi-mi:NUP62(display_short)|uniprotkb:62 kDa nucleoporin(gene name synonym)|uniprotkb:Nucleoporin Nup62(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676198|imex:IM-22977-113 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041004.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) refseq:NP_714941.1|ensembl:ENSG00000213024(gene)|ensembl:ENST00000352066(transcript)|ensembl:ENST00000422090(transcript)|ensembl:ENST00000596217(transcript)|ensembl:ENST00000597029(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007569"(cell aging)|go:"GO:0008219"(cell death)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0003682"(chromatin binding)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0051028"(mRNA transport)|go:"GO:0051425"(PTB domain binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072686"(mitotic spindle)|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|go:"GO:0090543"(Flemming body)|go:"GO:0098534"(centriole assembly)|go:"GO:1903438"(positive regulation of mitotic cytokinetic process)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007758(Nucleoporin, Nsp1-like, C-terminal)|interpro:IPR026010|interpro:IPR033072|mint:P37198|rcsb pdb:2H4D|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|refseq:NP_714940.1|refseq:NP_001180286.1|refseq:NP_036478.2|refseq:NP_057637.2|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|dip:DIP-29749N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:JALmnTn2BuPjeDXSyA8raxDgM0411909 rogid:v7mvKvTtVEnLMwcpUZIcdAzge009606 intact-crc:493B79B8B40E1863|rigid:uMd7gRCfPbGpX1IxaR8rSTAOZxQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:Q01844 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-739737|uniprotkb:Q92635|uniprotkb:Q96FE8|uniprotkb:Q96MX4|uniprotkb:Q9BWA2|uniprotkb:Q5THL0|intact:EBI-28987207|ensembl:ENSP00000381031|intact:EBI-10985407|uniprotkb:B0QYK1|uniprotkb:Q96MN4 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:ews_human(display_long)|uniprotkb:EWSR1(gene name)|psi-mi:EWSR1(display_short)|uniprotkb:EWS(gene name synonym)|uniprotkb:EWS oncogene(gene name synonym)|uniprotkb:Ewing sarcoma breakpoint region 1 protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676254|imex:IM-22977-123 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_001156757.1|refseq:NP_005234.1|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q01844|rcsb pdb:2CPE|interpro:IPR001876(Zinc finger, RanBP2-type)|ensembl:ENSG00000182944(gene)|ensembl:ENST00000397938(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001156759.1|refseq:NP_053733.2|refseq:NP_001156758.1|ensembl:ENST00000332035|ensembl:ENSP00000331699|ensembl:ENST00000333395|ensembl:ENSP00000327456|ensembl:ENSP00000381031|ensembl:ENST00000406548|ensembl:ENSP00000385726|ensembl:ENST00000414183|ensembl:ENSP00000400142|dip:DIP-34449N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:7PxoTjcmcdUA3clzf0eW+iCFaS49606 intact-crc:5BA7C302104BC834|rigid:BYm1nho/YSR651NDf7C7dvaMZqg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:P26196 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-351257|uniprotkb:Q5D048|ensembl:ENSP00000433704|ensembl:ENSP00000442266|ensembl:ENSP00000478754 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:ddx6_human(display_long)|uniprotkb:DDX6(gene name)|psi-mi:DDX6(display_short)|uniprotkb:HLR2(gene name synonym)|uniprotkb:RCK(gene name synonym)|uniprotkb:DEAD box protein 6(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p54(gene name synonym)|uniprotkb:Oncogene RCK(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676249|imex:IM-22977-122 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_004388.2|refseq:NP_001244120.1|ensembl:ENSG00000110367(gene)|ensembl:ENST00000526070(transcript)|ensembl:ENST00000534980(transcript)|ensembl:ENST00000620157(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000932"(P-body)|go:"GO:0001520"(outer dense fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045296"(cadherin binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0097227"(sperm annulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P26196|rcsb pdb:1VEC|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT5|rcsb pdb:5ANR|rcsb pdb:6F9S|rcsb pdb:6S8S|reactome:R-HSA-430039|refseq:XP_005271474.1|dip:DIP-29195N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:pBOpwnVU+BmxUyC/uo2ig53QRto9606 intact-crc:5280577C33FCD9E6|rigid:Qle6X+wzTjynIXb54Njjcw6vI1k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:Q8WW24 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-750487|ensembl:ENSP00000295201 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:tekt4_human(display_long)|uniprotkb:TEKT4(gene name)|psi-mi:TEKT4(display_short) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676244|imex:IM-22977-121 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_653306.1|ensembl:ENSG00000163060(gene)|ensembl:ENST00000295201(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0036126"(sperm flagellum)|go:"GO:0060271"(cilium assembly)|go:"GO:0060294"(cilium movement involved in cell motility)|interpro:IPR000435(Tektin) psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:uSPBMKPN9VTr6rsdxgUPpfWynIA9606 intact-crc:713139E4EEEA72A3|rigid:a6XBBxghgGxvMsBFAntpEH7LKA0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:Q8N4L8 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-1104933|ensembl:ENSP00000361392|uniprotkb:Q6RWT2 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:ccd24_human(display_long)|uniprotkb:CCDC24(gene name)|psi-mi:CCDC24(display_short) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676239|imex:IM-22977-120 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) ensembl:ENSG00000159214(gene)|ensembl:ENST00000372318(transcript)|go:"GO:0001835"(blastocyst hatching)|interpro:IPR031367|refseq:NP_689712.1|refseq:XP_016855930.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:+WHY6f4VV8Z2uvuWOUYqOSCN36o9606 intact-crc:28C45810B0050640|rigid:tzmQCoiSgdUyXUWls/F4IkdhXNM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:Q96FJ2 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-742371|uniprotkb:B2R5B4|ensembl:ENSP00000477310 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:dyl2_human(display_long)|uniprotkb:DYNLL2(gene name)|psi-mi:DYNLL2(display_short)|uniprotkb:Dynein light chain LC8-type 2(gene name synonym)|uniprotkb:DLC2(gene name synonym)|uniprotkb:8 kDa dynein light chain b(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676234|imex:IM-22977-119 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) go:"GO:0005813"(centrosome)|refseq:NP_542408.1|ensembl:ENSG00000264364(gene)|ensembl:ENST00000579991(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0007017"(microtubule-based process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0030286"(dynein complex)|go:"GO:0031475"(myosin V complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097542"(ciliary tip)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:Q96FJ2|rcsb pdb:2XQQ|rcsb pdb:3P8M|rcsb pdb:4D07|reactome:R-HSA-139910|reactome:R-HSA-141444|reactome:R-HSA-1632852|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-5620924|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:4RFpJF40RBja5mOvt/aCv3miiDU9606 intact-crc:970ECB6CAADE692C|rigid:gVX0bDFfeiIcpLN0X+JSBtPWPeQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:O43186 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-748171|uniprotkb:Q0QD45|ensembl:ENSP00000221996|ensembl:ENSP00000445565 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:crx_human(display_long)|uniprotkb:CRX(gene name)|psi-mi:CRX(display_short)|uniprotkb:CORD2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676229|imex:IM-22977-118 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_000545.1|ensembl:ENSG00000105392(gene)|ensembl:ENST00000221996(transcript)|ensembl:ENST00000539067(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050896"(response to stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:v/bkO/0iLzq1Q2HtieWQQ40RF9M9606 intact-crc:140978ED0879C2E7|rigid:CbXhSStMGDnr4S1rdtD3hZH+NyI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:Q9UK41 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-727424|uniprotkb:Q86VK0|ensembl:ENSP00000292510|ensembl:ENSP00000434064|ensembl:ENSP00000496519|ensembl:ENSP00000496693 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:vps28_human(display_long)|uniprotkb:VPS28(gene name)|psi-mi:VPS28(display_short)|uniprotkb:ESCRT-I complex subunit VPS28(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676289|imex:IM-22977-130 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_057292.1|refseq:NP_898880.1|ensembl:ENSG00000160948(gene)|ensembl:ENSG00000285339(gene)|ensembl:ENST00000292510(transcript)|ensembl:ENST00000526054(transcript)|ensembl:ENST00000642867(transcript)|ensembl:ENST00000643186(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR007143(Vacuolar protein sorting-associated, VPS28)|interpro:IPR017898|interpro:IPR017899|interpro:IPR037202|interpro:IPR037206|interpro:IPR038358|mint:Q9UK41|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:GUcc7bRf1LaLklAYVLEHRSihPjA9606 intact-crc:91D315258BA0214D|rigid:asB4TaUf88TiPLK6fnIODUbmeUo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:Q6PEX3 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-3957672|ensembl:ENSP00000353742|uniprotkb:B0RZD3 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:kr261_human(display_long)|uniprotkb:KRTAP26-1(gene name)|psi-mi:KRTAP26-1(display_short)|uniprotkb:KAP26.1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676284|imex:IM-22977-129 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) ensembl:ENSG00000197683(gene)|ensembl:ENST00000360542(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|interpro:IPR007951(PMG)|reactome:R-HSA-6805567|refseq:NP_981950.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:VKgQPRg2qO2FXQx0fQ/dd/5kMws9606 intact-crc:2A5B0D38F1CAB663|rigid:si8ReoMWQMPSvGPbjGA7CYOwLyY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:P19012 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676279|imex:IM-22977-128 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606 intact-crc:B2636FA2EA84FF8B|rigid:mKLJpXEWDfcaiLr6DaSSHYk4YbE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:Q9NP87 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-9675790|uniprotkb:Q86WQ9|uniprotkb:D3DVK4|uniprotkb:Q6P5X8|ensembl:ENSP00000242248 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:dpolm_human(display_long)|uniprotkb:POLM(gene name)|psi-mi:POLM(display_short)|uniprotkb:Terminal transferase(gene name synonym)|uniprotkb:polmu(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676274|imex:IM-22977-127 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_001271259.1|refseq:NP_001271260.1|refseq:NP_037416.1|rcsb pdb:6IPK|rcsb pdb:6IPL|rcsb pdb:6IPM|rcsb pdb:6IPN|rcsb pdb:6P1M|rcsb pdb:6P1N|rcsb pdb:6P1O|rcsb pdb:6P1P|rcsb pdb:6P1Q|rcsb pdb:6P1R|rcsb pdb:6P1S|rcsb pdb:6P1T|rcsb pdb:6P1U|rcsb pdb:6P1V|rcsb pdb:6P1W|rcsb pdb:6WIC|rcsb pdb:6WID|rcsb pdb:6WIE|rcsb pdb:7CO6|rcsb pdb:7CO8|rcsb pdb:7CO9|rcsb pdb:7COA|rcsb pdb:7COB|rcsb pdb:7COC|rcsb pdb:7COD|reactome:R-HSA-5693571|ensembl:ENSG00000122678(gene)|ensembl:ENST00000242248(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|interpro:IPR001357(BRCT)|interpro:IPR001726(DNA nucleotidylexotransferase)|interpro:IPR002054(DNA-directed DNA polymerase, family X)|interpro:IPR010996(DNA-directed DNA polymerase, family X, beta-like, N-terminal)|interpro:IPR018944|interpro:IPR019843|interpro:IPR022312|interpro:IPR027249|interpro:IPR027421|interpro:IPR028207|interpro:IPR029398|interpro:IPR036420|interpro:IPR037160|interpro:IPR043519|rcsb pdb:2DUN|rcsb pdb:2HTF|rcsb pdb:4LZD|rcsb pdb:4LZG|rcsb pdb:4M04|rcsb pdb:4M0A|rcsb pdb:4YCX|rcsb pdb:4YD1|rcsb pdb:4YD2|rcsb pdb:5TWP|rcsb pdb:5TWQ|rcsb pdb:5TWR|rcsb pdb:5TWS|rcsb pdb:5TXX|rcsb pdb:5TXZ|rcsb pdb:5TYB|rcsb pdb:5TYC|rcsb pdb:5TYD|rcsb pdb:5TYE|rcsb pdb:5TYF|rcsb pdb:5TYG|rcsb pdb:5TYU|rcsb pdb:5TYV|rcsb pdb:5TYW|rcsb pdb:5TYX|rcsb pdb:5TYY|rcsb pdb:5TYZ|rcsb pdb:5VZ7|rcsb pdb:5VZ8|rcsb pdb:5VZ9|rcsb pdb:5VZA|rcsb pdb:5VZB|rcsb pdb:5VZC|rcsb pdb:5VZD|rcsb pdb:5VZE|rcsb pdb:5VZF|rcsb pdb:5VZG|rcsb pdb:5VZH|rcsb pdb:5VZI|rcsb pdb:5W4F|rcsb pdb:5ZLC|rcsb pdb:6AEC|rcsb pdb:6AEH|rcsb pdb:6AK5|rcsb pdb:6AK6|rcsb pdb:6AK8|rcsb pdb:6AK9|rcsb pdb:6AKH|rcsb pdb:6IPD|rcsb pdb:6IPE|rcsb pdb:6IPF|rcsb pdb:6IPG|rcsb pdb:6IPH|rcsb pdb:6IPI|rcsb pdb:6IPJ psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:PjYb9sk0XvVaJwJ3JdGQY4IvenE9606 intact-crc:97FD137FDE4A6FA6|rigid:SDYmq+6CVOVi7/mRw1A+pYSXU6U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:P37198 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-347978|intact:EBI-28983799|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|uniprotkb:Q6GTM2|uniprotkb:Q503A4|uniprotkb:Q96C43|uniprotkb:Q9NSL1|uniprotkb:B3KWU5 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:nup62_human(display_long)|uniprotkb:NUP62(gene name)|psi-mi:NUP62(display_short)|uniprotkb:62 kDa nucleoporin(gene name synonym)|uniprotkb:Nucleoporin Nup62(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676269|imex:IM-22977-126 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_714941.1|ensembl:ENSG00000213024(gene)|ensembl:ENST00000352066(transcript)|ensembl:ENST00000422090(transcript)|ensembl:ENST00000596217(transcript)|ensembl:ENST00000597029(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007569"(cell aging)|go:"GO:0008219"(cell death)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0003682"(chromatin binding)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0051028"(mRNA transport)|go:"GO:0051425"(PTB domain binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072686"(mitotic spindle)|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|go:"GO:0090543"(Flemming body)|go:"GO:0098534"(centriole assembly)|go:"GO:1903438"(positive regulation of mitotic cytokinetic process)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007758(Nucleoporin, Nsp1-like, C-terminal)|interpro:IPR026010|interpro:IPR033072|mint:P37198|rcsb pdb:2H4D|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|refseq:NP_714940.1|refseq:NP_001180286.1|refseq:NP_036478.2|refseq:NP_057637.2|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|dip:DIP-29749N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:v7mvKvTtVEnLMwcpUZIcdAzge009606 intact-crc:A9265FCA866D1129|rigid:0aOeFxGwa2yIy+c4oRdVecWLcp8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:Q8N448 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-2340947|uniprotkb:Q6ZMH2|uniprotkb:Q5W0P0|uniprotkb:Q96SH4|ensembl:ENSP00000325929|ensembl:ENSP00000497224 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:lnx2_human(display_long)|uniprotkb:LNX2(gene name)|psi-mi:LNX2(display_short)|uniprotkb:PDZRN1(gene name synonym)|uniprotkb:Numb-binding protein 2(gene name synonym)|uniprotkb:PDZ domain-containing RING finger protein 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676264|imex:IM-22977-125 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_699202.1|refseq:XP_016875923.1|ensembl:ENSG00000139517(gene)|ensembl:ENST00000316334(transcript)|ensembl:ENST00000649248(transcript)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036034|mint:Q8N448|rcsb pdb:2VWR|rcsb pdb:5DIN|rcsb pdb:5E11|rcsb pdb:5E1Y|rcsb pdb:5E21|rcsb pdb:5E22 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:cIS5t4XkbnIgelDlUc692nI285g9606 intact-crc:9531175F3530B33F|rigid:Hu5/ge6BY/bCqsLnV0xjt5qq6yE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:Q8N448 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-2340947|uniprotkb:Q6ZMH2|uniprotkb:Q5W0P0|uniprotkb:Q96SH4|ensembl:ENSP00000325929|ensembl:ENSP00000497224 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:lnx2_human(display_long)|uniprotkb:LNX2(gene name)|psi-mi:LNX2(display_short)|uniprotkb:PDZRN1(gene name synonym)|uniprotkb:Numb-binding protein 2(gene name synonym)|uniprotkb:PDZ domain-containing RING finger protein 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676259|imex:IM-22977-124 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_699202.1|refseq:XP_016875923.1|ensembl:ENSG00000139517(gene)|ensembl:ENST00000316334(transcript)|ensembl:ENST00000649248(transcript)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036034|mint:Q8N448|rcsb pdb:2VWR|rcsb pdb:5DIN|rcsb pdb:5E11|rcsb pdb:5E1Y|rcsb pdb:5E21|rcsb pdb:5E22 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:cIS5t4XkbnIgelDlUc692nI285g9606 intact-crc:ED3D4EB622D84271|rigid:Hu5/ge6BY/bCqsLnV0xjt5qq6yE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:Q6ZUT1 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-3920396|ensembl:ENSP00000339076|ensembl:ENSP00000402208|uniprotkb:Q7Z357|uniprotkb:Q8N2T3|uniprotkb:Q6IN53|uniprotkb:Q5RL41 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:nkap1_human(display_long)|uniprotkb:NKAPD1(gene name)|psi-mi:NKAPD1(display_short)|uniprotkb:C11orf57(gene name synonym)|uniprotkb:NKAP domain containing protein 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676314|imex:IM-22977-135 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) ensembl:ENSG00000150776(gene)|ensembl:ENST00000280352(transcript)|ensembl:ENST00000420986(transcript)|go:"GO:0042802"(identical protein binding)|interpro:IPR043407|refseq:NP_001287946.1|refseq:NP_001287948.1|refseq:NP_001287950.1|refseq:NP_001076439.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:7Lz1Il3OjnAW5tcASdyVUZf+4y89606 intact-crc:3CA2AA4582BCA474|rigid:RHUQJj45h8uuE4w1Vwz00u4bxSE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:Q96HA8 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-741158|uniprotkb:B4DE68|uniprotkb:Q9NW95|ensembl:ENSP00000287387 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:ntaq1_human(display_long)|uniprotkb:NTAQ1(gene name)|psi-mi:NTAQ1(display_short)|uniprotkb:C8orf32(gene name synonym)|uniprotkb:Protein NH2-terminal glutamine deamidase(gene name synonym)|uniprotkb:WDYHV motif-containing protein 1(gene name synonym)|uniprotkb:WDYHV1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676309|imex:IM-22977-134 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_060494.1|refseq:NP_001269953.1|ensembl:ENSG00000156795(gene)|ensembl:ENST00000287387(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008418"(protein-N-terminal asparagine amidohydrolase activity)|interpro:IPR023128|interpro:IPR037132|interpro:IPR039733|mint:Q96HA8|rcsb pdb:3C9Q|rcsb pdb:4W79|rcsb pdb:6KGJ|go:"GO:0070773"(protein-N-terminal glutamine amidohydrolase activity) psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:RKX6ww+Z/Zw6bmOXa0r8C0mxlvc9606 intact-crc:C173B4B8349D1C72|rigid:ObbRcI481yv6Iu2z6fQ6TiH4nk0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:Q9P0T4 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-745520|uniprotkb:B2RDM6|ensembl:ENSP00000270451|ensembl:ENSP00000466047|ensembl:ENSP00000466564 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:zn581_human(display_long)|uniprotkb:ZNF581(gene name)|psi-mi:ZNF581(display_short)|uniprotkb:HSPC189(orf name) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676304|imex:IM-22977-133 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_057619.1|ensembl:ENSG00000171425(gene)|ensembl:ENST00000270451(transcript)|ensembl:ENST00000587252(transcript)|ensembl:ENST00000588537(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9P0T4|go:"GO:0005634"(nucleus)|refseq:XP_006723303.1|refseq:XP_016882356.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:SpE0ZPhcfXB4PnyufoyWq4iNAs89606 intact-crc:3997A503B3314641|rigid:fnZX+FQcRyfrXURrdYRIxpn3/3M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:Q66PJ3 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-2683099|uniprotkb:Q9NR05|uniprotkb:Q4F966|uniprotkb:Q9P2R9|uniprotkb:Q96BI2|uniprotkb:Q504R8|uniprotkb:A4UCR8|uniprotkb:B3V0L0|uniprotkb:B3V0L1 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:ar6p4_human(display_long)|uniprotkb:HSP-975(gene name synonym)|uniprotkb:HSVI-binding protein(gene name synonym)|uniprotkb:SR-15(gene name synonym)|uniprotkb:SRp25(gene name synonym)|uniprotkb:Splicing factor SRrp37(gene name synonym)|uniprotkb:ARL6IP4(gene name)|psi-mi:ARL6IP4(display_short) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676299|imex:IM-22977-132 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) interpro:IPR019532|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|refseq:NP_001002251.2|refseq:NP_001002252.2|refseq:NP_001265307.1|refseq:NP_001265308.1|refseq:NP_001265309.1|refseq:NP_061164.3|refseq:NP_057722.3|mint:Q66PJ3 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:ZNWWhsvMwbPRZb3BlP50N3hc4Ls9606 intact-crc:B68A24E41352AAA5|rigid:1mbGn8VQ0dzcakz03l44aI4mUKA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:Q9NZD8 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-742688|uniprotkb:B4DW44|uniprotkb:Q6ZMB6|ensembl:ENSP00000204566|ensembl:ENSP00000404111 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:spg21_human(display_long)|uniprotkb:Spastic paraplegia 21 autosomal recessive Mast syndrome protein(gene name synonym)|uniprotkb:Acid cluster protein 33(gene name synonym)|uniprotkb:SPG21(gene name)|psi-mi:SPG21(display_short)|uniprotkb:ACP33(gene name synonym)|uniprotkb:BM-019(orf name)|uniprotkb:GL010(orf name)|uniprotkb:Spastic paraplegia 21 protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676294|imex:IM-22977-131 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_001121361.1|refseq:NP_001121362.1|refseq:NP_057714.1|ensembl:ENSG00000090487(gene)|ensembl:ENST00000204566(transcript)|ensembl:ENST00000433215(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR026151|interpro:IPR029058|mint:Q9NZD8|refseq:XP_005254494.1|refseq:XP_016877786.1|refseq:XP_016877787.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:MoKySBpEYFNm7Lox/HM5nnkmhkA9606 intact-crc:293B34BFE1CC04D2|rigid:2R/jnnVOInc6+RMFMKYwJOOakKc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:P82932 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-716172|uniprotkb:Q96Q64|uniprotkb:Q9BSK8|uniprotkb:Q9BW89|uniprotkb:B2R573|ensembl:ENSP00000382250 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:rt06_human(display_long)|uniprotkb:MRPS6(gene name)|psi-mi:MRPS6(display_short)|uniprotkb:C21orf101(gene name synonym)|uniprotkb:RPMS6(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein bS6m(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676329|imex:IM-22977-138 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_115865.1|ensembl:ENSG00000243927(gene)|ensembl:ENST00000399312(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR000529(Ribosomal protein S6)|interpro:IPR014717(Translation elongation factor EF1B/ribosomal protein S6)|interpro:IPR035980|mint:P82932|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZSA|rcsb pdb:6ZS9|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:mMPTr45GZxT1pj2RBZvvG6TrQmo9606 intact-crc:1F6361D809E8D83B|rigid:hCeLrXkOSuops84LJobStx/OcXA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:Q9GZT8 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-740897|uniprotkb:Q9H2D2|uniprotkb:Q9HC18|uniprotkb:Q6X735|uniprotkb:Q53TX4|ensembl:ENSP00000386394|ensembl:ENSP00000387315|ensembl:ENSP00000498853 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:nif3l_human(display_long)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein(gene name synonym)|uniprotkb:MDS015(orf name)|uniprotkb:My018(orf name)|uniprotkb:NIF3L1(gene name)|psi-mi:NIF3L1(display_short)|uniprotkb:ALS2CR1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676324|imex:IM-22977-137 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_001129511.1|refseq:NP_001135827.1|refseq:NP_068596.2|refseq:XP_011509887.1|refseq:XP_011509884.1|refseq:XP_011509885.1|refseq:XP_011509886.1|refseq:NP_001135828.1|refseq:XP_005246799.1|refseq:XP_016860119.1|ensembl:ENSG00000196290(gene)|ensembl:ENST00000409020(transcript)|ensembl:ENST00000409357(transcript)|ensembl:ENST00000651500(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1903507"(negative regulation of nucleic acid-templated transcription)|interpro:IPR002678(NGG1p interacting factor 3, NIF3)|interpro:IPR017222(Uncharacterised conserved protein UCP037490, NIF3, eukaryota)|interpro:IPR036069|mint:Q9GZT8 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:Vvyb7CJpcwGtGAVKT2Zoqycr2yQ9606 intact-crc:F3E5EFD3F96829DD|rigid:ZM2PXr7lLwa1wyfEyh9xpDXOSjY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:A8K1J0 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-9675917 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:a8k1j0_human(display_long) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676319|imex:IM-22977-136 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) interpro:IPR035175 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:vDMi5ExMRZu+QfhPYYmxG+0DwB09606 intact-crc:082423DA97265FE5|rigid:ZkrRLhTGl78sUjJAReVhhiPemhE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:P23497 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676344|imex:IM-22977-141 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 intact-crc:4A2C314F84EC66C9|rigid:ZMlo7twhUJAFXioQwRaEUmDdd4Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:P35711 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-3505701|uniprotkb:Q86UK8|uniprotkb:Q8J017|uniprotkb:Q8J018|uniprotkb:Q8J019|uniprotkb:Q8J020|uniprotkb:Q8N1D9|uniprotkb:Q8N7E0|uniprotkb:Q8TEA4|uniprotkb:B7Z8V0|uniprotkb:F5H5B0|ensembl:ENSP00000398273 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:sox5_human(display_long)|uniprotkb:SOX5(gene name)|psi-mi:SOX5(display_short) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676339|imex:IM-22977-140 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_008871.3|refseq:NP_694534.1|refseq:NP_821078.1|refseq:NP_001248343.1|refseq:NP_001248344.1|ensembl:ENSG00000134532(gene)|ensembl:ENST00000451604(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001502"(cartilage condensation)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0045165"(cell fate commitment)|go:"GO:0051216"(cartilage development)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0061036"(positive regulation of cartilage development)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:2000741"(positive regulation of mesenchymal stem cell differentiation)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|mint:P35711|refseq:NP_001317714.1|refseq:XP_016875385.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:YVl5zcnqafFgRvQt8B79kMtbz+g9606 intact-crc:05317F4DDDC83665|rigid:DQz53+P9sHPbU/vTPfwDIijl15I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:P14672 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-367146|uniprotkb:Q14CX2|uniprotkb:Q05BQ3|ensembl:ENSP00000320935|ensembl:ENSP00000499804 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:glut4_human(display_long)|uniprotkb:SLC2A4(gene name)|psi-mi:SLC2A4(display_short)|uniprotkb:GLUT4(gene name synonym)|uniprotkb:Glucose transporter type 4, insulin-responsive(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676334|imex:IM-22977-139 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_001033.1|go:"GO:0055056"(D-glucose transmembrane transporter activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0098694"(regulation of synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0098793"(presynapse)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR002441("Glucose transporter, type 4 (GLUT4)")|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|reactome:R-HSA-1445148|reactome:R-HSA-189200|reactome:R-HSA-381340|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0012505"(endomembrane system)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031550"(positive regulation of brain-derived neurotrophic factor receptor signaling pathway)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0044381"(glucose import in response to insulin stimulus)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0046323"(glucose import)|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSG00000181856(gene)|ensembl:ENSG00000288174(gene)|ensembl:ENST00000317370(transcript)|ensembl:ENST00000673224(transcript)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005771"(multivesicular body)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0007611"(learning or memory)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010021"(amylopectin biosynthetic process) psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:P9bY7eO9/4e2pVIARFLZ3qmuwHA9606 intact-crc:8E75F7A934E03E06|rigid:RIQv16sIWDk5eo5ywFfali/h/4E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:Q8N5F7 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-721539|uniprotkb:Q96BQ2|uniprotkb:Q9H638|intact:EBI-745962|intact:EBI-1055594|uniprotkb:Q6IPW6|ensembl:ENSP00000360464 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:nkap_human(display_long)|uniprotkb:NKAP(gene name)|psi-mi:NKAP(display_short) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676359|imex:IM-22977-144 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_078804.2|ensembl:ENSG00000101882(gene)|ensembl:ENST00000371410(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046638"(positive regulation of alpha-beta T cell differentiation)|interpro:IPR009269(Protein of unknown function DUF926)|interpro:IPR040466|mint:Q8N5F7|rcsb pdb:6QDV psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:AiSgP+Qr12IZX1LBTsna82wmkks9606 intact-crc:DE1BB16C66710C50|rigid:p9CUP6zkHvup9CPs3SX8gqf6Ykc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:Q96CN9 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-746252|uniprotkb:Q9H6N7|ensembl:ENSP00000318821 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:gcc1_human(display_long)|uniprotkb:Golgi coiled-coil protein 1(gene name synonym)|uniprotkb:GCC1(gene name)|psi-mi:GCC1(display_short) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676354|imex:IM-22977-143 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_078799.2|ensembl:ENSG00000179562(gene)|ensembl:ENST00000321407(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0031267"(small GTPase binding)|interpro:IPR000237(GRIP)|reactome:R-HSA-6811440|go:"GO:0000138"(Golgi trans cisterna) psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:SCI+peKjPIvl/HbUUpHGM++qiRE9606 intact-crc:CE0A3EDFC6E15CF7|rigid:gDeQNnnU/SXaDQia3V+ioE8RHbw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:Q05516 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-711925|ensembl:ENSP00000338157|ensembl:ENSP00000376721|ensembl:ENSP00000506794|ensembl:ENSP00000506894|ensembl:ENSP00000506924|ensembl:ENSP00000506953|ensembl:ENSP00000507788|ensembl:ENSP00000508351|uniprotkb:Q8TAL4 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:zbt16_human(display_long)|uniprotkb:Zinc finger protein PLZF(gene name synonym)|uniprotkb:Promyelocytic leukemia zinc finger protein(gene name synonym)|uniprotkb:Zinc finger protein 145(gene name synonym)|uniprotkb:ZBTB16(gene name)|psi-mi:ZBTB16(display_short)|uniprotkb:PLZF(gene name synonym)|uniprotkb:ZNF145(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676349|imex:IM-22977-142 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) ensembl:ENSG00000109906(gene)|ensembl:ENST00000335953(transcript)|ensembl:ENST00000392996(transcript)|ensembl:ENST00000682278(transcript)|ensembl:ENST00000682697(transcript)|ensembl:ENST00000682971(transcript)|ensembl:ENST00000683318(transcript)|ensembl:ENST00000683554(transcript)|ensembl:ENST00000684295(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001823"(mesonephros development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043931"(ossification involved in bone maturation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048133"(male germ-line stem cell asymmetric division)|go:"GO:0051138"(positive regulation of NK T cell differentiation)|go:"GO:0051216"(cartilage development)|go:"GO:0061036"(positive regulation of cartilage development)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q05516|rcsb pdb:1BUO|rcsb pdb:1CS3|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_001018011.1|refseq:NP_005997.2|refseq:XP_016873746.1|refseq:XP_016873747.1|refseq:XP_016873748.1|dip:DIP-2654N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:wJmkU9GC3S18VXyYd8asd+hN+yU9606 intact-crc:2D45BC72B6328E7A|rigid:FQTttVzu5bsZTQmYQ/nlgfEx6r0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:Q8NHQ1 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676394|imex:IM-22977-151 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606 intact-crc:10A6E6B07ECE076F|rigid:LoP13yR1Vt/fK6BqoTRzlk2mxDc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:Q96MT8 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-741977|uniprotkb:Q96CR0|uniprotkb:Q9H8F5|uniprotkb:Q9H8N0|uniprotkb:D3DND8|uniprotkb:D3DND9|uniprotkb:D3DNE0|ensembl:ENSP00000426129|ensembl:ENSP00000475903|ensembl:ENSP00000502085|ensembl:ENSP00000506896 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:cep63_human(display_long)|uniprotkb:CEP63(gene name)|psi-mi:CEP63(display_short) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676389|imex:IM-22977-150 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) go:"GO:0000922"(spindle pole)|go:"GO:0005829"(cytosol)|refseq:NP_001035842.1|refseq:NP_001035843.1|refseq:NP_001035859.1|refseq:NP_079456.2|ensembl:ENSG00000182923(gene)|ensembl:ENST00000513612(transcript)|ensembl:ENST00000606977(transcript)|ensembl:ENST00000675561(transcript)|ensembl:ENST00000683596(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005814"(centriole)|go:"GO:0005813"(centrosome)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|interpro:IPR029608|interpro:IPR031470|mint:Q96MT8|rcsb pdb:6CSU|rcsb pdb:6CSV|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|go:"GO:0007099"(centriole replication)|refseq:XP_011511496.1|refseq:XP_005247854.1|refseq:XP_006713823.1|refseq:XP_016862743.1|refseq:XP_016862744.1|refseq:XP_016862745.1|refseq:XP_016862751.1|refseq:XP_016862752.1|refseq:XP_016862753.1|refseq:XP_016862755.1|refseq:XP_016862756.1|dip:DIP-36374N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:/WPfint+sTGNCYCH9XG5rPYSOm09606 intact-crc:24DB3D6C4A2AA317|rigid:95RNNJDoRmBJ84J5mCX6GqbxkMA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:Q96MT8 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-741977|uniprotkb:Q96CR0|uniprotkb:Q9H8F5|uniprotkb:Q9H8N0|uniprotkb:D3DND8|uniprotkb:D3DND9|uniprotkb:D3DNE0|ensembl:ENSP00000426129|ensembl:ENSP00000475903|ensembl:ENSP00000502085|ensembl:ENSP00000506896 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:cep63_human(display_long)|uniprotkb:CEP63(gene name)|psi-mi:CEP63(display_short) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676384|imex:IM-22977-149 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) go:"GO:0000922"(spindle pole)|go:"GO:0005829"(cytosol)|refseq:NP_001035842.1|refseq:NP_001035843.1|refseq:NP_001035859.1|refseq:NP_079456.2|ensembl:ENSG00000182923(gene)|ensembl:ENST00000513612(transcript)|ensembl:ENST00000606977(transcript)|ensembl:ENST00000675561(transcript)|ensembl:ENST00000683596(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005814"(centriole)|go:"GO:0005813"(centrosome)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|interpro:IPR029608|interpro:IPR031470|mint:Q96MT8|rcsb pdb:6CSU|rcsb pdb:6CSV|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|go:"GO:0007099"(centriole replication)|refseq:XP_011511496.1|refseq:XP_005247854.1|refseq:XP_006713823.1|refseq:XP_016862743.1|refseq:XP_016862744.1|refseq:XP_016862745.1|refseq:XP_016862751.1|refseq:XP_016862752.1|refseq:XP_016862753.1|refseq:XP_016862755.1|refseq:XP_016862756.1|dip:DIP-36374N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:/WPfint+sTGNCYCH9XG5rPYSOm09606 intact-crc:5CD764855DC25259|rigid:95RNNJDoRmBJ84J5mCX6GqbxkMA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:Q53HC0 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-719994|uniprotkb:Q9H697|uniprotkb:B3KNQ0|ensembl:ENSP00000238156|ensembl:ENSP00000488830 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:ccd92_human(display_long)|uniprotkb:Limkain beta-2(gene name synonym)|uniprotkb:CCDC92(gene name)|psi-mi:CCDC92(display_short) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676379|imex:IM-22977-148 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_079416.1|ensembl:ENSG00000119242(gene)|ensembl:ENSG00000275035(gene)|ensembl:ENST00000238156(transcript)|ensembl:ENST00000632401(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR033224|interpro:IPR039496|interpro:IPR040370|mint:Q53HC0|refseq:NP_001291886.1|refseq:NP_001291887.1|refseq:NP_001291888.1|refseq:NP_001291889.1|refseq:NP_001291890.1|refseq:XP_005253681.1|refseq:XP_016875473.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:Iu/FzTqEpzn8N5WUTt1OwoKWxyc9606 intact-crc:4E4E275976E701A1|rigid:+mXQgAsKwPv7YeAPcWkfB+ktYuI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:Q6ZVK8 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-740486|intact:EBI-954151|ensembl:ENSP00000480722|uniprotkb:Q9H687|uniprotkb:Q8IZ75 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:nud18_human(display_long)|uniprotkb:NUDT18(gene name)|psi-mi:NUDT18(display_short)|uniprotkb:2-hydroxy-dADP phosphatase(gene name synonym)|uniprotkb:7,8-dihydro-8-oxoguanine phosphatase(gene name synonym)|uniprotkb:MTH3(gene name synonym)|uniprotkb:MutT homolog 3(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 18(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676374|imex:IM-22977-147 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_079091.3|ensembl:ENST00000611621(transcript)|ensembl:ENSG00000275074(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0044715"(8-oxo-dGDP phosphatase activity)|go:"GO:0044716"(8-oxo-GDP phosphatase activity)|go:"GO:0044717"(8-hydroxy-dADP phosphatase activity)|go:"GO:0046057"(dADP catabolic process)|go:"GO:0046067"(dGDP catabolic process)|go:"GO:0046712"(GDP catabolic process)|go:"GO:0055086"(nucleobase-containing small molecule metabolic process)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR020476|interpro:IPR042970|rcsb pdb:3GG6|rcsb pdb:4HVY|reactome:R-HSA-2393930 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:IBrXB2HhvhcyxMTQ0Xs5hGiimzA9606 intact-crc:10B3C5C28E52874D|rigid:1OtfGNqqUHqlrfZWYQ+pqAosalQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:Q8N883 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-9675993|uniprotkb:Q9BSN8|uniprotkb:Q8TCF4|uniprotkb:Q494T8|ensembl:ENSP00000270649 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:zn614_human(display_long)|uniprotkb:ZNF614(gene name)|psi-mi:ZNF614(display_short) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676369|imex:IM-22977-146 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_079316.2|ensembl:ENSG00000142556(gene)|ensembl:ENST00000270649(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:DTfWPcCHy/ZIwvALRCnGC6SMX749606 intact-crc:CA2602DD65092E30|rigid:rCObw2hQbm9ASPbxbEzIH4N7K3I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:Q6ZVK8 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-740486|intact:EBI-954151|ensembl:ENSP00000480722|uniprotkb:Q9H687|uniprotkb:Q8IZ75 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:nud18_human(display_long)|uniprotkb:NUDT18(gene name)|psi-mi:NUDT18(display_short)|uniprotkb:2-hydroxy-dADP phosphatase(gene name synonym)|uniprotkb:7,8-dihydro-8-oxoguanine phosphatase(gene name synonym)|uniprotkb:MTH3(gene name synonym)|uniprotkb:MutT homolog 3(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 18(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676364|imex:IM-22977-145 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_079091.3|ensembl:ENST00000611621(transcript)|ensembl:ENSG00000275074(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0044715"(8-oxo-dGDP phosphatase activity)|go:"GO:0044716"(8-oxo-GDP phosphatase activity)|go:"GO:0044717"(8-hydroxy-dADP phosphatase activity)|go:"GO:0046057"(dADP catabolic process)|go:"GO:0046067"(dGDP catabolic process)|go:"GO:0046712"(GDP catabolic process)|go:"GO:0055086"(nucleobase-containing small molecule metabolic process)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR020476|interpro:IPR042970|rcsb pdb:3GG6|rcsb pdb:4HVY|reactome:R-HSA-2393930 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:IBrXB2HhvhcyxMTQ0Xs5hGiimzA9606 intact-crc:68BF9C2B99BA7603|rigid:1OtfGNqqUHqlrfZWYQ+pqAosalQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:Q8IUF8 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-751580|uniprotkb:Q6AHW4|uniprotkb:Q6SKS0|uniprotkb:Q8IU69|uniprotkb:Q8IUF6|uniprotkb:Q8IUF7|uniprotkb:Q96KB0|uniprotkb:Q96C17|uniprotkb:D3DN35|ensembl:ENSP00000328251|ensembl:ENSP00000377748 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:riox2_human(display_long)|uniprotkb:RIOX2(gene name)|psi-mi:RIOX2(display_short)|uniprotkb:60S ribosomal protein L27a histidine hydroxylase(gene name synonym)|uniprotkb:Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA(gene name synonym)|uniprotkb:Histone lysine demethylase MINA(gene name synonym)|uniprotkb:MDIG(gene name synonym)|uniprotkb:MINA(gene name synonym)|uniprotkb:MINA53(gene name synonym)|uniprotkb:MYC-induced nuclear antigen(gene name synonym)|uniprotkb:Mineral dust-induced gene protein(gene name synonym)|uniprotkb:NO52(gene name synonym)|uniprotkb:Nucleolar protein 52(gene name synonym)|uniprotkb:Ribosomal oxygenase MINA(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676429|imex:IM-22977-158 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_001035998.1|refseq:NP_116167.3|refseq:NP_694822.2|refseq:NP_001248758.1|refseq:XP_005247895.1|dip:DIP-28141N|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR039994|mint:Q8IUF8|rcsb pdb:2XDV|rcsb pdb:4BU2|rcsb pdb:4BXF|reactome:R-HSA-3214842|ensembl:ENSG00000170854(gene)|ensembl:ENST00000333396(transcript)|ensembl:ENST00000394198(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity) psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:tdjUsv9EuHn+AADASjfGu9U15Xc9606 intact-crc:252A2D4C9A99F704|rigid:8Ej0GGy0Jk6seRL3fySbBcP+s4I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:Q9BSW2 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-739773|uniprotkb:B4E1X0|uniprotkb:B9EK63|ensembl:ENSP00000409382 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:efc4b_human(display_long)|uniprotkb:CRACR2A(gene name)|psi-mi:CRACR2A(display_short)|uniprotkb:Calcium release-activated calcium channel regulator 2A(gene name synonym)|uniprotkb:Calcium release-activated channel regulator 2A(gene name synonym)|uniprotkb:EFCAB4B(gene name synonym)|uniprotkb:RAB46(gene name synonym)|uniprotkb:Ras-related protein Rab-46(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676424|imex:IM-22977-157 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_001138430.1|refseq:NP_116069.1|ensembl:ENSG00000130038(gene)|ensembl:ENST00000440314(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001772"(immunological synapse)|go:"GO:0002115"(store-operated calcium entry)|go:"GO:0002250"(adaptive immune response)|go:"GO:0003924"(GTPase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0031982"(vesicle)|go:"GO:0032237"(activation of store-operated calcium channel activity)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0034776"(response to histamine)|go:"GO:0035580"(specific granule lumen)|go:"GO:0045063"(T-helper 1 cell differentiation)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0051928"(positive regulation of calcium ion transport)|interpro:IPR001806(Ras GTPase)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|rcsb pdb:6PSD|reactome:R-HSA-6798695|interpro:IPR027417 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2021/04/12 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:IjhHTze6Dftzv9JltvNQgdATG+89606 intact-crc:F5AA7E5E971BB6B4|rigid:H72ss0pTZK5bFaAc2NLqCt2tX9U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:Q9BRK4 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-741037|ensembl:ENSP00000359240|ensembl:ENSP00000359243|uniprotkb:Q8N3I0|uniprotkb:Q96J79|uniprotkb:Q96JL2|uniprotkb:B1AL14|uniprotkb:D3DR72 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:lzts2_human(display_long)|uniprotkb:Protein LAPSER1(gene name synonym)|uniprotkb:LZTS2(gene name)|psi-mi:LZTS2(display_short)|uniprotkb:KIAA1813(gene name synonym)|uniprotkb:LAPSER1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676419|imex:IM-22977-156 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_115805.1|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:0031982"(vesicle)|go:"GO:0051013"(microtubule severing)|go:"GO:0051168"(nuclear export)|go:"GO:0051255"(spindle midzone assembly)|go:"GO:0060682"(primary ureteric bud growth)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR028597|mint:Q9BRK4|ensembl:ENSG00000107816(gene)|ensembl:ENST00000370220(transcript)|ensembl:ENST00000370223(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|refseq:XP_016872269.1|refseq:NP_001305028.1|refseq:NP_001305029.1|refseq:NP_001305030.1|refseq:XP_005270279.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:OaMJmnmfm6JniKUJeyg7fS6zRcw9606 intact-crc:05A833360CE92A6B|rigid:96c8F/VbsYsCoq7CtyIRoF8qkJc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:Q9BRK4 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-741037|ensembl:ENSP00000359240|ensembl:ENSP00000359243|uniprotkb:Q8N3I0|uniprotkb:Q96J79|uniprotkb:Q96JL2|uniprotkb:B1AL14|uniprotkb:D3DR72 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:lzts2_human(display_long)|uniprotkb:Protein LAPSER1(gene name synonym)|uniprotkb:LZTS2(gene name)|psi-mi:LZTS2(display_short)|uniprotkb:KIAA1813(gene name synonym)|uniprotkb:LAPSER1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676414|imex:IM-22977-155 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_115805.1|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:0031982"(vesicle)|go:"GO:0051013"(microtubule severing)|go:"GO:0051168"(nuclear export)|go:"GO:0051255"(spindle midzone assembly)|go:"GO:0060682"(primary ureteric bud growth)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR028597|mint:Q9BRK4|ensembl:ENSG00000107816(gene)|ensembl:ENST00000370220(transcript)|ensembl:ENST00000370223(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|refseq:XP_016872269.1|refseq:NP_001305028.1|refseq:NP_001305029.1|refseq:NP_001305030.1|refseq:XP_005270279.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:OaMJmnmfm6JniKUJeyg7fS6zRcw9606 intact-crc:7DA46ADF1B01DB25|rigid:96c8F/VbsYsCoq7CtyIRoF8qkJc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:Q9BRJ6 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-751612|ensembl:ENSP00000350011|ensembl:ENSP00000380286|ensembl:ENSP00000380288 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:cg050_human(display_long)|uniprotkb:FP15621(orf name)|uniprotkb:C7orf50(gene name)|psi-mi:C7orf50(display_short) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676409|imex:IM-22977-154 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_001127867.1|refseq:NP_001127868.1|refseq:NP_115726.1|refseq:NP_001305181.1|ensembl:ENSG00000146540(gene)|ensembl:ENST00000357429(transcript)|ensembl:ENST00000397098(transcript)|ensembl:ENST00000397100(transcript)|interpro:IPR019327|mint:Q9BRJ6|go:"GO:0003723"(RNA binding) psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:POftCOri0Nj8YUd5Kc3nNMDb41A9606 intact-crc:3DB0A98E1D1140A8|rigid:YdXIAWfPaUg+GBbWa5gbA7IFMl4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:Q9Y6D9 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-742610|uniprotkb:B3KR41|uniprotkb:Q9UNH0|uniprotkb:Q13312|uniprotkb:Q75MI0|uniprotkb:Q86UM4|ensembl:ENSP00000265854|ensembl:ENSP00000382562|ensembl:ENSP00000385334 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:md1l1_human(display_long)|uniprotkb:Mitotic arrest deficient 1-like protein 1(gene name synonym)|uniprotkb:Mitotic checkpoint MAD1 protein homolog(gene name synonym)|uniprotkb:Tax-binding protein 181(gene name synonym)|uniprotkb:MAD1L1(gene name)|psi-mi:MAD1L1(display_short)|uniprotkb:MAD1(gene name synonym)|uniprotkb:TXBP181(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676404|imex:IM-22977-153 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_001013858.1|refseq:NP_001013859.1|refseq:NP_003541.2|refseq:NP_001291452.1|refseq:NP_001291453.1|ensembl:ENSG00000002822(gene)|ensembl:ENST00000265854(transcript)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|interpro:IPR008672(Mitotic checkpoint)|mint:Q9Y6D9|rcsb pdb:1GO4|rcsb pdb:4DZO|rcsb pdb:7B1F|rcsb pdb:7B1H|rcsb pdb:7B1J|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENST00000399654(transcript)|ensembl:ENST00000406869(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043515"(kinetochore binding)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0048538"(thymus development)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|refseq:XP_005249934.1|dip:DIP-29654N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:9CcqpZlN0IgqC939rIo7vNgOvLQ9606 intact-crc:CA41D0DD31FD268B|rigid:A4O2lRO9MdWvEx4dU4LSkwWMY2w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:Q9H0B3 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-745878|uniprotkb:Q8N4G8|uniprotkb:Q96M14|uniprotkb:Q9C0I0|uniprotkb:B4DYH2|uniprotkb:E9PDE0|uniprotkb:E9PH54|uniprotkb:Q2KHR5|ensembl:ENSP00000470780 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:iqcn_human(display_long)|uniprotkb:IQCN(gene name)|psi-mi:IQCN(display_short)|uniprotkb:KIAA1683(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676399|imex:IM-22977-152 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_001138776.1|refseq:NP_001138777.1|refseq:NP_079525.1|ensembl:ENSG00000130518(gene)|ensembl:ENST00000600328(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR027417|interpro:IPR040124|refseq:XP_005260141.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:HxF5+Sq8vABdGwkzKy+JlbjLieQ9606 intact-crc:547FB206A54C19EB|rigid:IIkATO5NC0Xbf2o+77NdDE11zSY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:Q8TAE8 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-372506|uniprotkb:Q8IVM3|uniprotkb:Q8TE51|uniprotkb:Q969P9|uniprotkb:Q9BSM6|intact:EBI-28983431|ensembl:ENSP00000323065 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:g45ip_human(display_long)|uniprotkb:39S ribosomal protein L59, mitochondrial(gene name synonym)|uniprotkb:MRPL59(gene name synonym)|uniprotkb:CR6-interacting factor 1(gene name synonym)|uniprotkb:CKII beta-associating protein(gene name synonym)|uniprotkb:Papillomavirus L2-interacting nuclear protein 1(gene name synonym)|uniprotkb:p53-responsive gene 6 protein(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL64(gene name synonym)|uniprotkb:GADD45GIP1(gene name)|psi-mi:GADD45GIP1(display_short)|uniprotkb:PLINP1(gene name synonym)|uniprotkb:PRG6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676459|imex:IM-22977-164 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_443082.2|ensembl:ENSP00000323065|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|ensembl:ENSG00000179271(gene)|ensembl:ENST00000316939(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005840"(ribosome)|go:"GO:0007049"(cell cycle)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR018472|interpro:IPR043035|mint:Q8TAE8|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:lFY+2Pev2sxqaW9nhzemL0QO52s9606 intact-crc:8F40A9AD9612134F|rigid:OZXxVdZr2ds4yhNEbcKc+v1KJWw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:Q969F0 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-743099|ensembl:ENSP00000359375 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:fate1_human(display_long)|uniprotkb:Tumor antigen BJ-HCC-2(gene name synonym)|uniprotkb:Cancer/testis antigen 43(gene name synonym)|uniprotkb:FATE1(gene name)|psi-mi:FATE1(display_short)|uniprotkb:FATE(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676454|imex:IM-22977-163 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_149076.1|ensembl:ENSG00000147378(gene)|ensembl:ENST00000370350(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|interpro:IPR039153|interpro:IPR039433|mint:Q969F0 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:Nm1N6lO92MHr5rIKC007oouF5RE9606 intact-crc:829D3B26E7B16DFE|rigid:iPiOWoAK8YcOYXaqVvYEQVMFdNQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:Q9UJX2 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-396137|uniprotkb:O75433|uniprotkb:Q9BS73|uniprotkb:B4E3A2|uniprotkb:B7WP05|uniprotkb:Q53FN2|uniprotkb:A8K6E5|uniprotkb:D3DQB7|ensembl:ENSP00000378350 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:cdc23_human(display_long)|uniprotkb:CDC23(gene name)|psi-mi:CDC23(display_short)|uniprotkb:ANAPC8(gene name synonym)|uniprotkb:Anaphase-promoting complex subunit 8(gene name synonym)|uniprotkb:Cyclosome subunit 8(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676449|imex:IM-22977-162 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_004652.2|dip:DIP-32959N|ensembl:ENSG00000094880(gene)|ensembl:ENST00000394886(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007091"(metaphase/anaphase transition of mitotic cell cycle)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR007192(Cdc23)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q9UJX2|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:uTZL2UHzZHLoKnio/1LcuSzZpW09606 intact-crc:C33E800FD88AFF5A|rigid:PueJEhUoqfReAh4G02gJ+L0/XE8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:O14503 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-711810|uniprotkb:Q96TD3|ensembl:ENSP00000256495 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:bhe40_human(display_long)|uniprotkb:BHLHE40(gene name)|psi-mi:BHLHE40(display_short)|uniprotkb:Differentially expressed in chondrocytes protein 1(gene name synonym)|uniprotkb:Enhancer-of-split and hairy-related protein 2(gene name synonym)|uniprotkb:Stimulated by retinoic acid gene 13 protein(gene name synonym)|uniprotkb:BHLHB2(gene name synonym)|uniprotkb:DEC1(gene name synonym)|uniprotkb:SHARP2(gene name synonym)|uniprotkb:STRA13(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676444|imex:IM-22977-161 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) ensembl:ENSG00000134107(gene)|ensembl:ENST00000256495(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016604"(nuclear body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043426"(MRF binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|refseq:NP_003661.1|dip:DIP-36698N|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:O14503|reactome:R-HSA-1368108 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:JZrZ1Yo2PF33s9Lf8rLTHCqoptk9606 intact-crc:1408EDD2EC9C7302|rigid:zeSfVTS3SGpmz8h80EoQrhf7+G4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:Q9BY27 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-742953|ensembl:ENSP00000248879|uniprotkb:Q9BW33|uniprotkb:A8K1N7|uniprotkb:D3DX29|uniprotkb:B3KMC0 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:dgc6l_human(display_long)|uniprotkb:DiGeorge syndrome critical region 6-like protein(gene name synonym)|uniprotkb:DGCR6L(gene name)|psi-mi:DGCR6L(display_short) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676439|imex:IM-22977-160 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) go:"GO:0005634"(nucleus)|interpro:IPR010849(DiGeorge syndrome critical 6)|ensembl:ENSG00000128185(gene)|ensembl:ENST00000248879(transcript)|refseq:NP_150282.2 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:kgKOLihCtc75qwW051IZsGLspI09606 intact-crc:B6C4D773F4EAF955|rigid:yTAL/g6T3p01kWoPB364cDPj/og false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:Q6P1W5 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-946029|uniprotkb:B3KVT1|uniprotkb:Q96IC8|ensembl:ENSP00000435634|uniprotkb:D3DPR3|uniprotkb:E9PJ76 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:ca094_human(display_long)|uniprotkb:C1orf94(gene name)|psi-mi:C1orf94(display_short) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676434|imex:IM-22977-159 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_001128206.1|refseq:NP_116273.2|ensembl:ENSG00000142698(gene)|ensembl:ENST00000488417(transcript)|interpro:IPR031496 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:y1o4xWvTl2CBA1J7jsP7y8ZjLzM9606 intact-crc:FBE1ABCD7AC80E65|rigid:PzKsqQma60N7HsrFtZi4oMlw/5k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:P51116 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676484|imex:IM-22977-169 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606 intact-crc:8FE7400104E7C36E|rigid:85NnTT7HdQxPldXkFEuPqFPMbA0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:Q92530 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-945916|uniprotkb:A0AVQ9|uniprotkb:Q9H4I1|uniprotkb:D3DVW3|ensembl:ENSP00000327704|ensembl:ENSP00000338039 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:psmf1_human(display_long)|uniprotkb:PSMF1(gene name)|psi-mi:PSMF1(display_short) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676479|imex:IM-22977-168 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_006805.2|refseq:NP_848693.2|refseq:NP_001310336.1|ensembl:ENSG00000125818(gene)|ensembl:ENST00000333082(transcript)|ensembl:ENST00000335877(transcript)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070628"(proteasome binding)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|interpro:IPR013886(PI31 proteasome regulator)|interpro:IPR021625|rcsb pdb:2VT8|rcsb pdb:4OUH|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:QufCMzFs9wZBQO5l4iVOfn4dnvc9606 intact-crc:52C420D29DB2BAC9|rigid:6hrYTXiOPf45YCa8P2E7/It9CwM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:O00189 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-3914106|ensembl:ENSP00000352603|ensembl:ENSP00000412185|uniprotkb:Q8WV65|uniprotkb:Q9UHK9|uniprotkb:D6W5U1 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:ap4m1_human(display_long)|uniprotkb:AP4M1(gene name)|psi-mi:AP4M1(display_short)|uniprotkb:MUARP2(gene name synonym)|uniprotkb:Mu subunit of AP-4(gene name synonym)|uniprotkb:Mu-adaptin-related protein 2(gene name synonym)|uniprotkb:Mu4-adaptin(gene name synonym)|uniprotkb:AP-4 adaptor complex mu subunit(gene name synonym)|uniprotkb:Adaptor-related protein complex 4 subunit mu-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676474|imex:IM-22977-167 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) ensembl:ENSG00000221838(gene)|ensembl:ENST00000359593(transcript)|ensembl:ENST00000421755(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0008104"(protein localization)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030124"(AP-4 adaptor complex)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0031410"(cytoplasmic vesicle)|refseq:NP_004713.2|go:"GO:0031904"(endosome lumen)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090160"(Golgi to lysosome transport)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR001392(Clathrin adaptor, mu subunit)|interpro:IPR011012(Longin-like)|interpro:IPR018240|interpro:IPR022775|interpro:IPR028565|interpro:IPR036168|rcsb pdb:3L81|rcsb pdb:4MDR|reactome:R-HSA-432720 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:yAnydsX4RFJWI43arkgC7OcCUfM9606 intact-crc:6C079A2B1F1D7D2D|rigid:lSMcOA9ItLA5Gkny3PDGkonXrBw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:O14964 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676469|imex:IM-22977-166 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606 intact-crc:6C05D5058BF8824C|rigid:JRIG9zjTKInXfmKKer0WW9WQ4bU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:O14964 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676464|imex:IM-22977-165 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606 intact-crc:14098CEC9C107302|rigid:JRIG9zjTKInXfmKKer0WW9WQ4bU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14075 uniprotkb:Q9H1Q7 intact:EBI-9675533|uniprotkb:Q77YG4 intact:EBI-748452|uniprotkb:Q5JUA5|uniprotkb:Q5JUA6|uniprotkb:Q6PK19|uniprotkb:Q86WF5|uniprotkb:Q96CG7|uniprotkb:Q9H1Q6|uniprotkb:Q9H6D1|ensembl:ENSP00000353868 psi-mi:env_htl1c(display_long)|uniprotkb:env(gene name)|psi-mi:env(display_short)|uniprotkb:Env polyprotein(gene name synonym) psi-mi:ped1a_human(display_long)|uniprotkb:PCED1A(gene name)|psi-mi:PCED1A(display_short)|uniprotkb:C20orf81(gene name synonym)|uniprotkb:FAM113A(gene name synonym)|uniprotkb:Protein FAM113A(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-23(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676498|imex:IM-22977-170 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018154|refseq:NP_057865.1|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0055036"(virion membrane) refseq:NP_073597.2|refseq:NP_001258097.1|refseq:XP_005260861.1|refseq:XP_005260862.1|ensembl:ENSG00000132635(gene)|ensembl:ENST00000360652(transcript)|interpro:IPR026057|mint:Q9H1Q7 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:QMX2JJtovlfFJqzVbOdRDHnLTgQ11927 rogid:L1RRthUFVoaARhQE6LnQV1QLqLk9606 intact-crc:A325AA601E9C0726|rigid:mKrFoBssKUwQwa7qXzhiZ7ilwc0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14075 uniprotkb:Q9Y3Q8 intact:EBI-9675533|uniprotkb:Q77YG4 intact:EBI-739485|uniprotkb:A8MWR6|ensembl:ENSP00000300181|uniprotkb:A4D2C3|uniprotkb:D6W5V9 psi-mi:env_htl1c(display_long)|uniprotkb:env(gene name)|psi-mi:env(display_short)|uniprotkb:Env polyprotein(gene name synonym) psi-mi:t22d4_human(display_long)|uniprotkb:TSC22D4(gene name)|psi-mi:TSC22D4(display_short)|uniprotkb:TILZ2(gene name synonym)|uniprotkb:TSC22-related-inducible leucine zipper protein 2(gene name synonym)|uniprotkb:Tsc-22-like protein THG-1(gene name synonym)|uniprotkb:THG1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676509|imex:IM-22977-171 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018154|refseq:NP_057865.1|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0055036"(virion membrane) ensembl:ENSG00000166925(gene)|ensembl:ENST00000300181(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006970"(response to osmotic stress)|interpro:IPR000580(TSC-22 / Dip / Bun)|interpro:IPR042553|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_112197.1|refseq:NP_001289972.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:QMX2JJtovlfFJqzVbOdRDHnLTgQ11927 rogid:eL12cHY76zEPOXzT1HFKPSckS8Y9606 intact-crc:4C3C24B3806895A0|rigid:B3rb3smPGmDI+EotSgjayUxhJ/I false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q2Q067 uniprotkb:Q13015 intact:EBI-9675545 intact:EBI-6269719|ensembl:ENSP00000357917 psi-mi:q2q067_9dela(display_long)|uniprotkb:HBZ(gene name)|psi-mi:HBZ(display_short) psi-mi:af1q_human(display_long)|uniprotkb:MLLT11(gene name)|psi-mi:MLLT11(display_short)|uniprotkb:AF1Q(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11908(humt-)|taxid:11908(Human T-lymphotropic virus 1) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676519|imex:IM-22977-173 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6DNQ|interpro:IPR026220|go:"GO:0016032"(viral process) ensembl:ENSG00000213190(gene)|ensembl:ENST00000368921(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR026778|interpro:IPR033461|mint:Q13015|refseq:NP_006809.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:j9b0X2J4Nu0iW1SeHJj8GlrL3IE11908 rogid:23mnJAG1OcDgM7eT2rTi1Gv0ZgA9606 intact-crc:0C4F4CA17E75EBA7|rigid:dTWVRZzUodcD/NE2txop73gyvEY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q2Q067 uniprotkb:O95251 intact:EBI-9675545 intact:EBI-473199|uniprotkb:B3KN74|uniprotkb:B4DFB4|uniprotkb:B4DFE0|uniprotkb:B4DF85|uniprotkb:B4DGY4|uniprotkb:E7ER15|uniprotkb:G5E9K7|intact:EBI-10986821|ensembl:ENSP00000259021 psi-mi:q2q067_9dela(display_long)|uniprotkb:HBZ(gene name)|psi-mi:HBZ(display_short) psi-mi:kat7_human(display_long)|uniprotkb:KAT7(gene name)|psi-mi:KAT7(display_short)|uniprotkb:HBO1(gene name synonym)|uniprotkb:HBOa(gene name synonym)|uniprotkb:MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2(gene name synonym)|uniprotkb:Histone acetyltransferase binding to ORC1(gene name synonym)|uniprotkb:MYST2(gene name synonym)|uniprotkb:Lysine acetyltransferase 7(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11908(humt-)|taxid:11908(Human T-lymphotropic virus 1) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676524|imex:IM-22977-174 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6DNQ|interpro:IPR026220|go:"GO:0016032"(viral process) refseq:NP_001186084.1|refseq:NP_001186085.1|refseq:NP_001186086.1|refseq:NP_001186087.1|refseq:NP_008998.1|dip:DIP-29697N|ensembl:ENSG00000136504(gene)|ensembl:ENST00000259021(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031098"(stress-activated protein kinase signaling cascade)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0036409"(histone H3-K14 acetyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0072708"(response to sorbitol)|go:"GO:0072710"(response to hydroxyurea)|go:"GO:0072716"(response to actinomycin D)|go:"GO:0072720"(response to dithiothreitol)|go:"GO:0072739"(response to anisomycin)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:0090734"(site of DNA damage)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902035"(positive regulation of hematopoietic stem cell proliferation)|go:"GO:2000819"(regulation of nucleotide-excision repair)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR002717(MOZ/SAS-like protein)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR036060|interpro:IPR036388|interpro:IPR040706|mint:O95251|rcsb pdb:5GK9|rcsb pdb:6MAJ|rcsb pdb:6MAK|reactome:R-HSA-3214847 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:j9b0X2J4Nu0iW1SeHJj8GlrL3IE11908 rogid:K27pgvPEe1/+rZXYUkPfMY7PZMs9606 intact-crc:0B62F9211A478297|rigid:7DdFZCqzKV+fETi0a7eODFXuIgs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q2Q067 uniprotkb:P02794 intact:EBI-9675545 intact:EBI-713259|uniprotkb:Q3KRA8|uniprotkb:Q3SWW1|ensembl:ENSP00000273550|ensembl:ENSP00000484477|uniprotkb:B3KNR5 psi-mi:q2q067_9dela(display_long)|uniprotkb:HBZ(gene name)|psi-mi:HBZ(display_short) psi-mi:frih_human(display_long)|uniprotkb:Cell proliferation-inducing gene 15 protein(gene name synonym)|uniprotkb:FTH1(gene name)|psi-mi:FTH1(display_short)|uniprotkb:FTH(gene name synonym)|uniprotkb:FTHL6(gene name synonym)|uniprotkb:PIG15(orf name)|uniprotkb:OK/SW-cl.84(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11908(humt-)|taxid:11908(Human T-lymphotropic virus 1) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676529|imex:IM-22977-175 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6DNQ|interpro:IPR026220|go:"GO:0016032"(viral process) refseq:NP_002023.2|ensembl:ENSG00000167996(gene)|ensembl:ENST00000273550(transcript)|ensembl:ENST00000620041(transcript)|go:"GO:0004322"(ferroxidase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006880"(intracellular sequestering of iron ion)|go:"GO:0006955"(immune response)|go:"GO:0008043"(intracellular ferritin complex)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008199"(ferric iron binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0044754"(autolysosome)|mint:P02794|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:1FHA|rcsb pdb:2CEI|rcsb pdb:2CHI|rcsb pdb:2CIH|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001519(Ferritin, N-terminal)|interpro:IPR008331(Ferritin and Dps)|interpro:IPR009040(Ferritin-like)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR012347(Ferritin-related)|interpro:IPR014034(Ferritin, conserved site)|rcsb pdb:2CLU|rcsb pdb:2CN6|rcsb pdb:2CN7|rcsb pdb:2FHA|rcsb pdb:2IU2|rcsb pdb:2Z6M|rcsb pdb:3AJO|rcsb pdb:3AJP|rcsb pdb:3AJQ|rcsb pdb:3ERZ|rcsb pdb:3ES3|rcsb pdb:4DYX|rcsb pdb:4DYY|rcsb pdb:4DYZ|rcsb pdb:4Y08|rcsb pdb:4YKH|rcsb pdb:4ZJK|rcsb pdb:5CMQ|rcsb pdb:5CMR|rcsb pdb:5GN8|rcsb pdb:5GOU|rcsb pdb:5JKK|rcsb pdb:5JKL|rcsb pdb:5JKM|rcsb pdb:5N26|rcsb pdb:5N27|rcsb pdb:5UP7|rcsb pdb:5UP8|rcsb pdb:5UP9|rcsb pdb:5VTD|rcsb pdb:5XB1|rcsb pdb:5YI5|rcsb pdb:5ZND|rcsb pdb:6B8F|rcsb pdb:6B8G|rcsb pdb:4DZ0|rcsb pdb:6FTV|rcsb pdb:6GSR|rcsb pdb:6H5I|rcsb pdb:6H6T|rcsb pdb:6H6U|rcsb pdb:6IPC|rcsb pdb:6IPO|rcsb pdb:6IPP|rcsb pdb:6IPQ|rcsb pdb:6J4A|rcsb pdb:6J7G|rcsb pdb:6JOB|rcsb pdb:6JPS|rcsb pdb:6KE2|rcsb pdb:6KE4|rcsb pdb:4OYN|rcsb pdb:6M52|rcsb pdb:6M54|rcsb pdb:6WYF|rcsb pdb:6WYG|rcsb pdb:6WYH|rcsb pdb:6Z6U|rcsb pdb:6Z9E|rcsb pdb:6Z9F|rcsb pdb:7A6A|rcsb pdb:7A6B|rcsb pdb:7CK8|rcsb pdb:7CK9|rcsb pdb:7JGK|rcsb pdb:7JGL|rcsb pdb:7JGM|rcsb pdb:7JGN|rcsb pdb:7JGO|rcsb pdb:7JGP|rcsb pdb:7JGQ|rcsb pdb:7K26|rcsb pdb:7K3V|rcsb pdb:7K3W|reactome:R-HSA-3000480|reactome:R-HSA-432722|reactome:R-HSA-6798695|reactome:R-HSA-917937|dip:DIP-38301N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:j9b0X2J4Nu0iW1SeHJj8GlrL3IE11908 rogid:TchHgRpv+inA8BQ5i0OHaa267tQ9606 intact-crc:57FF341A1629F1BD|rigid:VYNMsot3bR90yEWhV8bCJBDq9y0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q2Q067 uniprotkb:Q15287 intact:EBI-9675545 intact:EBI-395959|uniprotkb:A8K1P0|uniprotkb:B4DDU8|uniprotkb:B4DZU7|uniprotkb:B7ZA17|uniprotkb:O75308|uniprotkb:Q32P25|uniprotkb:Q8WY42|uniprotkb:Q9NYG3|ensembl:ENSP00000301730|ensembl:ENSP00000315859|ensembl:ENSP00000380275|ensembl:ENSP00000457723|ensembl:ENSP00000457820 psi-mi:q2q067_9dela(display_long)|uniprotkb:HBZ(gene name)|psi-mi:HBZ(display_short) psi-mi:rnps1_human(display_long)|uniprotkb:SR-related protein LDC2(gene name synonym)|uniprotkb:RNPS1(gene name)|psi-mi:RNPS1(display_short)|uniprotkb:LDC2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11908(humt-)|taxid:11908(Human T-lymphotropic virus 1) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676514|imex:IM-22977-172 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6DNQ|interpro:IPR026220|go:"GO:0016032"(viral process) refseq:NP_006702.1|refseq:NP_542161.1|refseq:NP_001273554.1|refseq:NP_001273555.1|refseq:NP_001273556.1|ensembl:ENSG00000205937(gene)|ensembl:ENST00000301730(transcript)|ensembl:ENST00000320225(transcript)|ensembl:ENST00000397086(transcript)|ensembl:ENST00000565678(transcript)|ensembl:ENST00000568631(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0061574"(ASAP complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034201|interpro:IPR035979|mint:Q15287|rcsb pdb:4A8X|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-9010553|reactome:R-HSA-975957|refseq:XP_005255105.1|refseq:XP_005255106.1|refseq:XP_016878363.1|dip:DIP-32943N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:j9b0X2J4Nu0iW1SeHJj8GlrL3IE11908 rogid:nANu/nh/pD/F6dYE2Sa28OegPGs9606 intact-crc:7443E02AF7445CE9|rigid:b7IxA2EbkcyvNChamphjTr0AjQE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C206 uniprotkb:Q96R06 intact:EBI-9675596|uniprotkb:O56230 intact:EBI-413317|uniprotkb:O95213|uniprotkb:Q9BWE8|uniprotkb:Q9NT17|uniprotkb:Q9UFE6|intact:EBI-28972684|ensembl:ENSP00000323300 psi-mi:rex_htl1c(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-1(gene name synonym)|uniprotkb:p27Rex(gene name synonym) psi-mi:spag5_human(display_long)|uniprotkb:SPAG5(gene name)|psi-mi:SPAG5(display_short)|uniprotkb:Astrin(gene name synonym)|uniprotkb:Mitotic spindle-associated protein p126(gene name synonym)|uniprotkb:Deepest(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676564|imex:IM-22977-182 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1EXY|refseq:NP_057863.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) refseq:NP_006452.3|ensembl:ENSP00000323300|ensembl:ENSG00000076382(gene)|ensembl:ENST00000321765(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007051"(spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0016604"(nuclear body)|go:"GO:0030496"(midbody)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0036064"(ciliary basal body)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0051301"(cell division)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR028728|mint:Q96R06|dip:DIP-30998N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:Jg3y2XqUP/JBerfBYcxMesTuQFQ11927 rogid:WOMksaINKpqSxqeGIzbmcSRcgdw9606 intact-crc:5560BC93E10513C8|rigid:GZPtivvl1EWB/yUq46LpaLg7z2k false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q2Q067 uniprotkb:Q15038 intact:EBI-9675545 intact:EBI-724310|ensembl:ENSP00000394699|uniprotkb:E9PB45|uniprotkb:A8K254|uniprotkb:B4DDT5|uniprotkb:C9JA96|uniprotkb:C9JP84|uniprotkb:B4E1G3|uniprotkb:F8VU62 psi-mi:q2q067_9dela(display_long)|uniprotkb:HBZ(gene name)|psi-mi:HBZ(display_short) psi-mi:dazp2_human(display_long)|uniprotkb:Deleted in azoospermia-associated protein 2(gene name synonym)|uniprotkb:DAZAP2(gene name)|psi-mi:DAZAP2(display_short)|uniprotkb:KIAA0058(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11908(humt-)|taxid:11908(Human T-lymphotropic virus 1) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676559|imex:IM-22977-181 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6DNQ|interpro:IPR026220|go:"GO:0016032"(viral process) ensembl:ENSG00000183283(gene)|ensembl:ENST00000412716(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050699"(WW domain binding)|interpro:IPR022730|mint:Q15038|refseq:NP_001129736.1|refseq:NP_055579.1|ensembl:ENSP00000394699|ensembl:ENST00000425012|ensembl:ENSP00000408251|ensembl:ENST00000439799|ensembl:ENSP00000398804|ensembl:ENST00000449723|ensembl:ENSP00000412812|ensembl:ENST00000549555|ensembl:ENSP00000448051|ensembl:ENST00000549732|ensembl:ENSP00000446554|refseq:NP_001129741.1|refseq:NP_001129739.1|refseq:NP_001129740.1|refseq:NP_001129738.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:j9b0X2J4Nu0iW1SeHJj8GlrL3IE11908 rogid:ASRqCZBG4q1U/y95PUSMKsgfm/g9606 intact-crc:0C4D01BABD6EADA7|rigid:k4XC3Bxm8qxHmMtz4Sq5gJdyg1g false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q2Q067 uniprotkb:Q9UH92 intact:EBI-9675545 intact:EBI-741109|intact:EBI-28976799|ensembl:ENSP00000246912|uniprotkb:Q53XM6|uniprotkb:Q96FL2|uniprotkb:Q9H2V0|uniprotkb:Q9H2V1|uniprotkb:Q9H2V2|uniprotkb:Q9NXN3|uniprotkb:B2RAV8|uniprotkb:A8K2J3|uniprotkb:B2RD73 psi-mi:q2q067_9dela(display_long)|uniprotkb:HBZ(gene name)|psi-mi:HBZ(display_short) psi-mi:mlx_human(display_long)|uniprotkb:Max-like bHLHZip protein(gene name synonym)|uniprotkb:BHLHD13(gene name synonym)|uniprotkb:Protein BigMax(gene name synonym)|uniprotkb:Transcription factor-like protein 4(gene name synonym)|uniprotkb:MLX(gene name)|psi-mi:MLX(display_short)|uniprotkb:TCFL4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 13(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11908(humt-)|taxid:11908(Human T-lymphotropic virus 1) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676554|imex:IM-22977-180 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6DNQ|interpro:IPR026220|go:"GO:0016032"(viral process) refseq:NP_733752.1|refseq:NP_937847.1|refseq:NP_937848.1|ensembl:ENSG00000108788(gene)|ensembl:ENST00000246912(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR032647|interpro:IPR036638|reactome:R-HSA-163765|go:"GO:0005654"(nucleoplasm)|ensembl:ENSP00000246912|ensembl:ENST00000346833|ensembl:ENSP00000320913|ensembl:ENST00000435881|ensembl:ENSP00000416627 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:j9b0X2J4Nu0iW1SeHJj8GlrL3IE11908 rogid:5zIr/dC+5Gre7BiEy/8g0MEdppY9606 intact-crc:F65F2DAFAB3D18B4|rigid:qa+eFixyWgLr29JX/uHLc0Sjnik false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q2Q067 uniprotkb:Q9HD26 intact:EBI-9675545 intact:EBI-349832|uniprotkb:A6NM30|uniprotkb:Q59FS4|uniprotkb:Q969U8|ensembl:ENSP00000357484 psi-mi:q2q067_9dela(display_long)|uniprotkb:HBZ(gene name)|psi-mi:HBZ(display_short) psi-mi:gopc_human(display_long)|uniprotkb:CAL(gene name synonym)|uniprotkb:FIG(gene name synonym)|uniprotkb:GOPC(gene name)|psi-mi:GOPC(display_short)|uniprotkb:PDZ protein interacting specifically with TC10(gene name synonym)|uniprotkb:CFTR-associated ligand(gene name synonym)|uniprotkb:Fused in glioblastoma(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11908(humt-)|taxid:11908(Human T-lymphotropic virus 1) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676549|imex:IM-22977-179 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6DNQ|interpro:IPR026220|go:"GO:0016032"(viral process) refseq:NP_001017408.1|refseq:NP_065132.1|go:"GO:0043004"(cytoplasmic sequestering of CFTR protein)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045176"(apical protein localization)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR038879|mint:Q9HD26|rcsb pdb:2DC2|rcsb pdb:2LOB|rcsb pdb:4E34|rcsb pdb:4E35|rcsb pdb:4JOE|rcsb pdb:4JOF|rcsb pdb:4JOG|rcsb pdb:4JOH|rcsb pdb:4JOJ|rcsb pdb:4JOK|rcsb pdb:4JOP|rcsb pdb:4JOR|rcsb pdb:4K6Y|rcsb pdb:4K72|rcsb pdb:4K75|rcsb pdb:4K76|rcsb pdb:4K78|rcsb pdb:4NMO|rcsb pdb:4NMP|rcsb pdb:4NMQ|rcsb pdb:4NMR|rcsb pdb:4NMS|rcsb pdb:4NMT|go:"GO:0042802"(identical protein binding)|rcsb pdb:4NMV|rcsb pdb:4Q6H|rcsb pdb:4Q6S|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6OV7|rcsb pdb:6V84|rcsb pdb:6XNJ|reactome:R-HSA-5627083|reactome:R-HSA-9013406|ensembl:ENSG00000047932(gene)|ensembl:ENST00000368498(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0010360"(negative regulation of anion channel activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030425"(dendrite)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0032991"(protein-containing complex) psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:j9b0X2J4Nu0iW1SeHJj8GlrL3IE11908 rogid:bXzu5wvJifZwB+Q52cgC4tZQl/k9606 intact-crc:704E7CDDF1E92A2D|rigid:hWgX/hgFqbIsPKT0U437nmr2u40 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q2Q067 uniprotkb:Q15365 intact:EBI-9675545 intact:EBI-946095|uniprotkb:Q13157|uniprotkb:Q14975|ensembl:ENSP00000305556 psi-mi:q2q067_9dela(display_long)|uniprotkb:HBZ(gene name)|psi-mi:HBZ(display_short) psi-mi:pcbp1_human(display_long)|uniprotkb:PCBP1(gene name)|psi-mi:PCBP1(display_short)|uniprotkb:Alpha-CP1(gene name synonym)|uniprotkb:Nucleic acid-binding protein SUB2.3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11908(humt-)|taxid:11908(Human T-lymphotropic virus 1) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676544|imex:IM-22977-178 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6DNQ|interpro:IPR026220|go:"GO:0016032"(viral process) refseq:NP_006187.2|dip:DIP-38136N|ensembl:ENSG00000169564(gene)|ensembl:ENST00000303577(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098847"(sequence-specific single stranded DNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15365|rcsb pdb:1WVN|rcsb pdb:1ZTG|rcsb pdb:3VKE|reactome:R-HSA-72163|reactome:R-HSA-72203 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:j9b0X2J4Nu0iW1SeHJj8GlrL3IE11908 rogid:x72fawo4plQ+ipfqIoREIDHc2bA9606 intact-crc:74431428C2255CE9|rigid:QfbjiTWvFxGWmySHh6WpWP4NvfI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q2Q067 uniprotkb:P31249 intact:EBI-9675545 intact:EBI-3957655|ensembl:ENSP00000249440|ensembl:ENSP00000386498|ensembl:ENSP00000507129|uniprotkb:Q99955|uniprotkb:Q9BSC5 psi-mi:q2q067_9dela(display_long)|uniprotkb:HBZ(gene name)|psi-mi:HBZ(display_short) psi-mi:hxd3_human(display_long)|uniprotkb:HOXD3(gene name)|psi-mi:HOXD3(display_short)|uniprotkb:HOX1D(gene name synonym)|uniprotkb:HOX4A(gene name synonym)|uniprotkb:Homeobox protein Hox-4A(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11908(humt-)|taxid:11908(Human T-lymphotropic virus 1) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676534|imex:IM-22977-176 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6DNQ|interpro:IPR026220|go:"GO:0016032"(viral process) ensembl:ENSG00000128652(gene)|ensembl:ENST00000249440(transcript)|ensembl:ENST00000410016(transcript)|ensembl:ENST00000683222(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016235"(aggresome)|go:"GO:0016604"(nuclear body)|go:"GO:0030878"(thyroid gland development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051216"(cartilage development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR025281|reactome:R-HSA-5617472|refseq:XP_011509367.1|refseq:XP_011509368.1|refseq:NP_008829.3|refseq:XP_005246566.1|refseq:XP_005246567.1|refseq:XP_005246568.1|refseq:XP_005246570.1|refseq:XP_006712540.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:j9b0X2J4Nu0iW1SeHJj8GlrL3IE11908 rogid:6egSlcCWXDnEWbOnwNGI/0ZxBM49606 intact-crc:57FD7BBB6D41DF1E|rigid:xDboQUlGrEHbADgxPl8tFHEDGPA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q2Q067 uniprotkb:P32243 intact:EBI-9675545 intact:EBI-954480|uniprotkb:Q6GTV3|uniprotkb:Q9HAW3|uniprotkb:B2RAN5|uniprotkb:Q9P2R1|ensembl:ENSP00000343819|ensembl:ENSP00000386185|ensembl:ENSP00000452336|ensembl:ENSP00000500061 psi-mi:q2q067_9dela(display_long)|uniprotkb:HBZ(gene name)|psi-mi:HBZ(display_short) psi-mi:otx2_human(display_long)|uniprotkb:Orthodenticle homolog 2(gene name synonym)|uniprotkb:OTX2(gene name)|psi-mi:OTX2(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11908(humt-)|taxid:11908(Human T-lymphotropic virus 1) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676539|imex:IM-22977-177 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6DNQ|interpro:IPR026220|go:"GO:0016032"(viral process) refseq:NP_068374.1|refseq:NP_758840.1|refseq:NP_001257452.1|refseq:NP_001257453.1|refseq:NP_001257454.1|ensembl:ENSG00000165588(gene)|ensembl:ENST00000339475(transcript)|ensembl:ENST00000408990(transcript)|ensembl:ENST00000555006(transcript)|ensembl:ENST00000673035(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007411"(axon guidance)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0030426"(growth cone)|go:"GO:0030900"(forebrain development)|go:"GO:0030901"(midbrain development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0040036"(regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0090009"(primitive streak formation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000543"(positive regulation of gastrulation)|interpro:IPR001356(Homeobox)|interpro:IPR003022(Transcription factor Otx2)|interpro:IPR003025(Transcription factor Otx)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:j9b0X2J4Nu0iW1SeHJj8GlrL3IE11908 rogid:ceYynldw4n+AnFOVi5L0PONYj609606 intact-crc:57FE56716DCC7C1E|rigid:9HKjcGKrnbQsUIHtBlVMjmBJj70 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C206 uniprotkb:P37198 intact:EBI-9675596|uniprotkb:O56230 intact:EBI-347978|intact:EBI-28983799|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|uniprotkb:Q6GTM2|uniprotkb:Q503A4|uniprotkb:Q96C43|uniprotkb:Q9NSL1|uniprotkb:B3KWU5 psi-mi:rex_htl1c(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-1(gene name synonym)|uniprotkb:p27Rex(gene name synonym) psi-mi:nup62_human(display_long)|uniprotkb:NUP62(gene name)|psi-mi:NUP62(display_short)|uniprotkb:62 kDa nucleoporin(gene name synonym)|uniprotkb:Nucleoporin Nup62(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676599|imex:IM-22977-189 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1EXY|refseq:NP_057863.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) refseq:NP_714941.1|ensembl:ENSG00000213024(gene)|ensembl:ENST00000352066(transcript)|ensembl:ENST00000422090(transcript)|ensembl:ENST00000596217(transcript)|ensembl:ENST00000597029(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007569"(cell aging)|go:"GO:0008219"(cell death)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0003682"(chromatin binding)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0051028"(mRNA transport)|go:"GO:0051425"(PTB domain binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072686"(mitotic spindle)|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|go:"GO:0090543"(Flemming body)|go:"GO:0098534"(centriole assembly)|go:"GO:1903438"(positive regulation of mitotic cytokinetic process)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007758(Nucleoporin, Nsp1-like, C-terminal)|interpro:IPR026010|interpro:IPR033072|mint:P37198|rcsb pdb:2H4D|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|refseq:NP_714940.1|refseq:NP_001180286.1|refseq:NP_036478.2|refseq:NP_057637.2|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|dip:DIP-29749N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:Jg3y2XqUP/JBerfBYcxMesTuQFQ11927 rogid:v7mvKvTtVEnLMwcpUZIcdAzge009606 intact-crc:A9110C50A6A54C24|rigid:4FMEsLx4zgQj7SHGCI1f9JblGzs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C206 uniprotkb:Q8N448 intact:EBI-9675596|uniprotkb:O56230 intact:EBI-2340947|uniprotkb:Q6ZMH2|uniprotkb:Q5W0P0|uniprotkb:Q96SH4|ensembl:ENSP00000325929|ensembl:ENSP00000497224 psi-mi:rex_htl1c(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-1(gene name synonym)|uniprotkb:p27Rex(gene name synonym) psi-mi:lnx2_human(display_long)|uniprotkb:LNX2(gene name)|psi-mi:LNX2(display_short)|uniprotkb:PDZRN1(gene name synonym)|uniprotkb:Numb-binding protein 2(gene name synonym)|uniprotkb:PDZ domain-containing RING finger protein 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676594|imex:IM-22977-188 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1EXY|refseq:NP_057863.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) refseq:NP_699202.1|refseq:XP_016875923.1|ensembl:ENSG00000139517(gene)|ensembl:ENST00000316334(transcript)|ensembl:ENST00000649248(transcript)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036034|mint:Q8N448|rcsb pdb:2VWR|rcsb pdb:5DIN|rcsb pdb:5E11|rcsb pdb:5E1Y|rcsb pdb:5E21|rcsb pdb:5E22 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:Jg3y2XqUP/JBerfBYcxMesTuQFQ11927 rogid:cIS5t4XkbnIgelDlUc692nI285g9606 intact-crc:950644C515F8EE32|rigid:75b2LoQRYcBqemSLaxTZkX5CZX4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C206 uniprotkb:Q8N448 intact:EBI-9675596|uniprotkb:O56230 intact:EBI-2340947|uniprotkb:Q6ZMH2|uniprotkb:Q5W0P0|uniprotkb:Q96SH4|ensembl:ENSP00000325929|ensembl:ENSP00000497224 psi-mi:rex_htl1c(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-1(gene name synonym)|uniprotkb:p27Rex(gene name synonym) psi-mi:lnx2_human(display_long)|uniprotkb:LNX2(gene name)|psi-mi:LNX2(display_short)|uniprotkb:PDZRN1(gene name synonym)|uniprotkb:Numb-binding protein 2(gene name synonym)|uniprotkb:PDZ domain-containing RING finger protein 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676589|imex:IM-22977-187 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1EXY|refseq:NP_057863.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) refseq:NP_699202.1|refseq:XP_016875923.1|ensembl:ENSG00000139517(gene)|ensembl:ENST00000316334(transcript)|ensembl:ENST00000649248(transcript)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036034|mint:Q8N448|rcsb pdb:2VWR|rcsb pdb:5DIN|rcsb pdb:5E11|rcsb pdb:5E1Y|rcsb pdb:5E21|rcsb pdb:5E22 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:Jg3y2XqUP/JBerfBYcxMesTuQFQ11927 rogid:cIS5t4XkbnIgelDlUc692nI285g9606 intact-crc:ED0A1D2C02101F7C|rigid:75b2LoQRYcBqemSLaxTZkX5CZX4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C206 uniprotkb:O14641 intact:EBI-9675596|uniprotkb:O56230 intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3 psi-mi:rex_htl1c(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-1(gene name synonym)|uniprotkb:p27Rex(gene name synonym) psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676584|imex:IM-22977-186 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1EXY|refseq:NP_057863.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:Jg3y2XqUP/JBerfBYcxMesTuQFQ11927 rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606 intact-crc:F4B0E4EFEAB3FB85|rigid:5+hz7SScxJR48jHh6c3fpIGSdgM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C206 uniprotkb:Q96FJ2 intact:EBI-9675596|uniprotkb:O56230 intact:EBI-742371|uniprotkb:B2R5B4|ensembl:ENSP00000477310 psi-mi:rex_htl1c(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-1(gene name synonym)|uniprotkb:p27Rex(gene name synonym) psi-mi:dyl2_human(display_long)|uniprotkb:DYNLL2(gene name)|psi-mi:DYNLL2(display_short)|uniprotkb:Dynein light chain LC8-type 2(gene name synonym)|uniprotkb:DLC2(gene name synonym)|uniprotkb:8 kDa dynein light chain b(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676574|imex:IM-22977-184 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1EXY|refseq:NP_057863.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) go:"GO:0005813"(centrosome)|refseq:NP_542408.1|ensembl:ENSG00000264364(gene)|ensembl:ENST00000579991(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0007017"(microtubule-based process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0030286"(dynein complex)|go:"GO:0031475"(myosin V complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097542"(ciliary tip)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:Q96FJ2|rcsb pdb:2XQQ|rcsb pdb:3P8M|rcsb pdb:4D07|reactome:R-HSA-139910|reactome:R-HSA-141444|reactome:R-HSA-1632852|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-5620924|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:Jg3y2XqUP/JBerfBYcxMesTuQFQ11927 rogid:4RFpJF40RBja5mOvt/aCv3miiDU9606 intact-crc:973998F68A163421|rigid:Nh0EMng3CiDDBeEjvC43fAW+OyU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C206 uniprotkb:O43186 intact:EBI-9675596|uniprotkb:O56230 intact:EBI-748171|uniprotkb:Q0QD45|ensembl:ENSP00000221996|ensembl:ENSP00000445565 psi-mi:rex_htl1c(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-1(gene name synonym)|uniprotkb:p27Rex(gene name synonym) psi-mi:crx_human(display_long)|uniprotkb:CRX(gene name)|psi-mi:CRX(display_short)|uniprotkb:CORD2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676569|imex:IM-22977-183 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1EXY|refseq:NP_057863.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) refseq:NP_000545.1|ensembl:ENSG00000105392(gene)|ensembl:ENST00000221996(transcript)|ensembl:ENST00000539067(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050896"(response to stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:Jg3y2XqUP/JBerfBYcxMesTuQFQ11927 rogid:v/bkO/0iLzq1Q2HtieWQQ40RF9M9606 intact-crc:F4B186FF07F54A60|rigid:1I6FqAFm29fEgwnuKuim24HT63Y false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6PF05 uniprotkb:P0C206 intact:EBI-8656864|ensembl:ENSP00000422188|uniprotkb:Q96LJ2|intact:MINT-8163808|uniprotkb:Q6RGS4|uniprotkb:Q8N7R3|uniprotkb:G8IJH6 intact:EBI-9675596|uniprotkb:O56230 psi-mi:tt23l_human(display_long)|uniprotkb:TTC23L(gene name)|psi-mi:TTC23L(display_short) psi-mi:rex_htl1c(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-1(gene name synonym)|uniprotkb:p27Rex(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676579|imex:IM-22977-185 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000205838(gene)|ensembl:ENST00000505624(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0030496"(midbody)|go:"GO:0034976"(response to endoplasmic reticulum stress)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR042621|mint:Q6PF05|refseq:NP_001304878.1|refseq:NP_653326.3 rcsb pdb:1EXY|refseq:NP_057863.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) psi-mi:"MI:0471"(mint) comment:mint - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:SRndoUysST7RgIovvs89vd30vMk9606 rogid:Jg3y2XqUP/JBerfBYcxMesTuQFQ11927 intact-crc:2ACB102174273604|rigid:ZAN3rdneLPDamL9kMFNrIq2H8bs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C206 uniprotkb:P63165 intact:EBI-9675596|uniprotkb:O56230 intact:EBI-80140|uniprotkb:P55856|uniprotkb:Q6FGG0|uniprotkb:Q6NZ62|uniprotkb:Q93068|intact:EBI-28970052|ensembl:ENSP00000376076|ensembl:ENSP00000376077|uniprotkb:B2R4I5|uniprotkb:A8MUS8 psi-mi:rex_htl1c(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-1(gene name synonym)|uniprotkb:p27Rex(gene name synonym) psi-mi:sumo1_human(display_long)|uniprotkb:SUMO1(gene name)|psi-mi:SUMO1(display_short)|uniprotkb:Sentrin(gene name synonym)|uniprotkb:Ubiquitin-like protein SMT3C(gene name synonym)|uniprotkb:Ubiquitin-homology domain protein PIC1(gene name synonym)|uniprotkb:Ubiquitin-like protein UBL1(gene name synonym)|uniprotkb:GAP-modifying protein 1(gene name synonym)|uniprotkb:SMT3 homolog 3(gene name synonym)|uniprotkb:SMT3C(gene name synonym)|uniprotkb:SMT3H3(gene name synonym)|uniprotkb:UBL1(gene name synonym)|uniprotkb:OK/SW-cl.43(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676609|imex:IM-22977-191 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1EXY|refseq:NP_057863.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) refseq:NP_001005781.1|refseq:NP_003343.1|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045759"(negative regulation of action potential)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:0060021"(roof of mouth development)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0097165"(nuclear stress granule)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|mint:P63165|rcsb pdb:1A5R|rcsb pdb:1TGZ|rcsb pdb:1WYW|rcsb pdb:1Y8R|rcsb pdb:1Z5S|rcsb pdb:2ASQ|rcsb pdb:2BF8|rcsb pdb:2G4D|rcsb pdb:2IO2|rcsb pdb:2IY0|rcsb pdb:2IY1|rcsb pdb:2KQS|rcsb pdb:2LAS|rcsb pdb:2MW5|rcsb pdb:2N1A|rcsb pdb:2N1V|rcsb pdb:2PE6|rcsb pdb:2UYZ|rcsb pdb:2VRR|rcsb pdb:3KYC|rcsb pdb:3KYD|rcsb pdb:3RZW|rcsb pdb:3UIP|rcsb pdb:4WJN|rcsb pdb:4WJO|rcsb pdb:4WJP|rcsb pdb:4WJQ|rcsb pdb:5AEK|rcsb pdb:5B7A|rcsb pdb:5ELJ|rcsb pdb:5GHD|rcsb pdb:6EOP|rcsb pdb:6EOT|rcsb pdb:6J4I|rcsb pdb:6JXU|rcsb pdb:6JXV|rcsb pdb:6K5T|rcsb pdb:6TRW|rcsb pdb:6UYO|rcsb pdb:6UYP|rcsb pdb:6UYQ|rcsb pdb:6UYR|rcsb pdb:6UYS|ensembl:ENSG00000116030(gene)|ensembl:ENST00000392245(transcript)|ensembl:ENST00000392246(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010621"(negative regulation of transcription by transcription factor localization)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019899"(enzyme binding)|rcsb pdb:6UYU|rcsb pdb:6UYV|rcsb pdb:6UYX|rcsb pdb:6UYY|rcsb pdb:6UYZ|rcsb pdb:6V7P|rcsb pdb:6V7Q|rcsb pdb:6V7R|rcsb pdb:6UYT|rcsb pdb:6V7S|rcsb pdb:6WW3|rcsb pdb:6XOG|rcsb pdb:6XOH|rcsb pdb:6XOI|reactome:R-HSA-3065676|reactome:R-HSA-3065678|reactome:R-HSA-3065679|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-4551638|reactome:R-HSA-877312|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000392244|ensembl:ENSP00000376075|ensembl:ENSP00000376076|ensembl:ENSP00000376077|refseq:NP_001005782.1|dip:DIP-29080N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:Jg3y2XqUP/JBerfBYcxMesTuQFQ11927 rogid:mflrn+v4fHL8UdmLodfZBZA6eAQ9606 intact-crc:7E5A938DC58C8E00|rigid:t7EF4fKWWh55UZDohaw+Ju+t6Kc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C206 uniprotkb:Q9NZD8 intact:EBI-9675596|uniprotkb:O56230 intact:EBI-742688|uniprotkb:B4DW44|uniprotkb:Q6ZMB6|ensembl:ENSP00000204566|ensembl:ENSP00000404111 psi-mi:rex_htl1c(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-1(gene name synonym)|uniprotkb:p27Rex(gene name synonym) psi-mi:spg21_human(display_long)|uniprotkb:Spastic paraplegia 21 autosomal recessive Mast syndrome protein(gene name synonym)|uniprotkb:Acid cluster protein 33(gene name synonym)|uniprotkb:SPG21(gene name)|psi-mi:SPG21(display_short)|uniprotkb:ACP33(gene name synonym)|uniprotkb:BM-019(orf name)|uniprotkb:GL010(orf name)|uniprotkb:Spastic paraplegia 21 protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676614|imex:IM-22977-192 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1EXY|refseq:NP_057863.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) refseq:NP_001121361.1|refseq:NP_001121362.1|refseq:NP_057714.1|ensembl:ENSG00000090487(gene)|ensembl:ENST00000204566(transcript)|ensembl:ENST00000433215(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR026151|interpro:IPR029058|mint:Q9NZD8|refseq:XP_005254494.1|refseq:XP_016877786.1|refseq:XP_016877787.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:Jg3y2XqUP/JBerfBYcxMesTuQFQ11927 rogid:MoKySBpEYFNm7Lox/HM5nnkmhkA9606 intact-crc:290C6725C10459DF|rigid:bgkC4cu3dTUi1zvtGwDBkwzL61c false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C206 uniprotkb:Q53EZ4 intact:EBI-9675596|uniprotkb:O56230 intact:EBI-747776|uniprotkb:Q32WF5|uniprotkb:Q3MV20|uniprotkb:Q5VY28|uniprotkb:Q6N034|ensembl:ENSP00000360540|uniprotkb:Q96H32|uniprotkb:Q9NVS7|uniprotkb:B2RDG8|intact:EBI-10173536|uniprotkb:D3DR37|intact:EBI-28973801 psi-mi:rex_htl1c(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-1(gene name synonym)|uniprotkb:p27Rex(gene name synonym) psi-mi:cep55_human(display_long)|uniprotkb:Up-regulated in colon cancer 6(gene name synonym)|uniprotkb:CEP55(gene name)|psi-mi:CEP55(display_short)|uniprotkb:URCC6(gene name synonym)|uniprotkb:C10orf3(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676619|imex:IM-22977-193 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1EXY|refseq:NP_057863.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) refseq:NP_001120654.1|refseq:NP_060601.3|ensembl:ENSG00000138180(gene)|ensembl:ENST00000371485(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|mint:Q53EZ4|rcsb pdb:3E1R|rcsb pdb:3WUT|rcsb pdb:3WUU|rcsb pdb:3WUV|go:"GO:0005814"(centriole)|ensembl:ENSP00000360540|dip:DIP-44581N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:Jg3y2XqUP/JBerfBYcxMesTuQFQ11927 rogid:tuo36vVb8ZgPDR81YjZFNEg559w9606 intact-crc:C75D22F0E16B9C59|rigid:yhhSNDtugoLmK9/ZM9LQkj2SQag false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C206 uniprotkb:Q9GZT8 intact:EBI-9675596|uniprotkb:O56230 intact:EBI-740897|uniprotkb:Q9H2D2|uniprotkb:Q9HC18|uniprotkb:Q6X735|uniprotkb:Q53TX4|ensembl:ENSP00000386394|ensembl:ENSP00000387315|ensembl:ENSP00000498853 psi-mi:rex_htl1c(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-1(gene name synonym)|uniprotkb:p27Rex(gene name synonym) psi-mi:nif3l_human(display_long)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein(gene name synonym)|uniprotkb:MDS015(orf name)|uniprotkb:My018(orf name)|uniprotkb:NIF3L1(gene name)|psi-mi:NIF3L1(display_short)|uniprotkb:ALS2CR1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676624|imex:IM-22977-194 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1EXY|refseq:NP_057863.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) refseq:NP_001129511.1|refseq:NP_001135827.1|refseq:NP_068596.2|refseq:XP_011509887.1|refseq:XP_011509884.1|refseq:XP_011509885.1|refseq:XP_011509886.1|refseq:NP_001135828.1|refseq:XP_005246799.1|refseq:XP_016860119.1|ensembl:ENSG00000196290(gene)|ensembl:ENST00000409020(transcript)|ensembl:ENST00000409357(transcript)|ensembl:ENST00000651500(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1903507"(negative regulation of nucleic acid-templated transcription)|interpro:IPR002678(NGG1p interacting factor 3, NIF3)|interpro:IPR017222(Uncharacterised conserved protein UCP037490, NIF3, eukaryota)|interpro:IPR036069|mint:Q9GZT8 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:Jg3y2XqUP/JBerfBYcxMesTuQFQ11927 rogid:Vvyb7CJpcwGtGAVKT2Zoqycr2yQ9606 intact-crc:F3D2BC49D9A074D0|rigid:4NMGGQW91m+i2YQg0k5ZtqLL550 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C206 uniprotkb:Q9H4K1 intact:EBI-9675596|uniprotkb:O56230 intact:EBI-740128|uniprotkb:Q6ICD0|uniprotkb:Q9Y413|ensembl:ENSP00000483356|uniprotkb:A0A087X0F7 psi-mi:rex_htl1c(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-1(gene name synonym)|uniprotkb:p27Rex(gene name synonym) psi-mi:ribc2_human(display_long)|uniprotkb:RIBC2(gene name)|psi-mi:RIBC2(display_short)|uniprotkb:C22orf11(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676604|imex:IM-22977-190 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1EXY|refseq:NP_057863.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) ensembl:ENSG00000128408(gene)|ensembl:ENST00000614167(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR008805(RIB43A)|refseq:XP_005261581.1|refseq:NP_056468.3 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2019/11/14 rogid:Jg3y2XqUP/JBerfBYcxMesTuQFQ11927 rogid:rU6ggF8fZGGy7ICGFHxeMZQLkw49606 intact-crc:67F0194E743BCF8E|rigid:DAO5fJ3tQ4SSM7vG0klip2Rqyqs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C206 uniprotkb:P23497 intact:EBI-9675596|uniprotkb:O56230 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 psi-mi:rex_htl1c(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-1(gene name synonym)|uniprotkb:p27Rex(gene name synonym) psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676629|imex:IM-22977-195 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1EXY|refseq:NP_057863.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:Jg3y2XqUP/JBerfBYcxMesTuQFQ11927 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 intact-crc:4A1B62D5A4243BC4|rigid:UcDjCflEfLDER3KTBmkMsoilAu4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8N3Z6 uniprotkb:P0C206 intact:EBI-7265024|uniprotkb:Q9P0F0|uniprotkb:Q8TBK8|uniprotkb:Q8N2M1|uniprotkb:Q5T0Q9|uniprotkb:D3DRQ0|uniprotkb:Q9H648|uniprotkb:Q8N4J2|uniprotkb:Q5T0Q8|intact:MINT-1182798|uniprotkb:B2RCI4|uniprotkb:Q5T0R0|ensembl:ENSP00000337839|ensembl:ENSP00000443113 intact:EBI-9675596|uniprotkb:O56230 psi-mi:zchc7_human(display_long)|uniprotkb:ZCCHC7(gene name)|psi-mi:ZCCHC7(display_short)|uniprotkb:TRAMP-like complex RNA-binding factor ZCCHC7(gene name synonym)|uniprotkb:HSPC086(orf name) psi-mi:rex_htl1c(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-1(gene name synonym)|uniprotkb:p27Rex(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676639|imex:IM-22977-197 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115602.2|refseq:XP_005251665.1|refseq:XP_005251669.1|ensembl:ENSG00000147905(gene)|ensembl:ENST00000336755(transcript)|ensembl:ENST00000534928(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036875|refseq:NP_001276048.1|refseq:NP_001276049.1|refseq:NP_001276050.1 rcsb pdb:1EXY|refseq:NP_057863.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) psi-mi:"MI:0471"(mint) comment:mint|comment:homomint - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:zm8NMOhdnKspXWuNvY/gjLTMQcI9606 rogid:Jg3y2XqUP/JBerfBYcxMesTuQFQ11927 intact-crc:C0CC2FAAFC58F1FA|rigid:mWavqKwWQSDYdLFgkXFfSaIT95w false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C206 uniprotkb:Q9BRK4 intact:EBI-9675596|uniprotkb:O56230 intact:EBI-741037|ensembl:ENSP00000359240|ensembl:ENSP00000359243|uniprotkb:Q8N3I0|uniprotkb:Q96J79|uniprotkb:Q96JL2|uniprotkb:B1AL14|uniprotkb:D3DR72 psi-mi:rex_htl1c(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-1(gene name synonym)|uniprotkb:p27Rex(gene name synonym) psi-mi:lzts2_human(display_long)|uniprotkb:Protein LAPSER1(gene name synonym)|uniprotkb:LZTS2(gene name)|psi-mi:LZTS2(display_short)|uniprotkb:KIAA1813(gene name synonym)|uniprotkb:LAPSER1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676649|imex:IM-22977-199 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1EXY|refseq:NP_057863.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) refseq:NP_115805.1|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:0031982"(vesicle)|go:"GO:0051013"(microtubule severing)|go:"GO:0051168"(nuclear export)|go:"GO:0051255"(spindle midzone assembly)|go:"GO:0060682"(primary ureteric bud growth)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR028597|mint:Q9BRK4|ensembl:ENSG00000107816(gene)|ensembl:ENST00000370220(transcript)|ensembl:ENST00000370223(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|refseq:XP_016872269.1|refseq:NP_001305028.1|refseq:NP_001305029.1|refseq:NP_001305030.1|refseq:XP_005270279.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:Jg3y2XqUP/JBerfBYcxMesTuQFQ11927 rogid:OaMJmnmfm6JniKUJeyg7fS6zRcw9606 intact-crc:059F60AC2C217766|rigid:qKnVDPtBw11oLxC2439IbDFJUWA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C206 uniprotkb:Q9BRK4 intact:EBI-9675596|uniprotkb:O56230 intact:EBI-741037|ensembl:ENSP00000359240|ensembl:ENSP00000359243|uniprotkb:Q8N3I0|uniprotkb:Q96J79|uniprotkb:Q96JL2|uniprotkb:B1AL14|uniprotkb:D3DR72 psi-mi:rex_htl1c(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-1(gene name synonym)|uniprotkb:p27Rex(gene name synonym) psi-mi:lzts2_human(display_long)|uniprotkb:Protein LAPSER1(gene name synonym)|uniprotkb:LZTS2(gene name)|psi-mi:LZTS2(display_short)|uniprotkb:KIAA1813(gene name synonym)|uniprotkb:LAPSER1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676644|imex:IM-22977-198 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1EXY|refseq:NP_057863.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) refseq:NP_115805.1|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:0031982"(vesicle)|go:"GO:0051013"(microtubule severing)|go:"GO:0051168"(nuclear export)|go:"GO:0051255"(spindle midzone assembly)|go:"GO:0060682"(primary ureteric bud growth)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR028597|mint:Q9BRK4|ensembl:ENSG00000107816(gene)|ensembl:ENST00000370220(transcript)|ensembl:ENST00000370223(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|refseq:XP_016872269.1|refseq:NP_001305028.1|refseq:NP_001305029.1|refseq:NP_001305030.1|refseq:XP_005270279.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:Jg3y2XqUP/JBerfBYcxMesTuQFQ11927 rogid:OaMJmnmfm6JniKUJeyg7fS6zRcw9606 intact-crc:7D9339453BC98628|rigid:qKnVDPtBw11oLxC2439IbDFJUWA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C206 uniprotkb:P63279 intact:EBI-9675596|uniprotkb:O56230 intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69 psi-mi:rex_htl1c(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-1(gene name synonym)|uniprotkb:p27Rex(gene name synonym) psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676634|imex:IM-22977-196 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1EXY|refseq:NP_057863.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:Jg3y2XqUP/JBerfBYcxMesTuQFQ11927 rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606 intact-crc:AE20613D722AC69F|rigid:oGQ0JrQU9ht9/aRdjBi/8l9qCbo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C206 uniprotkb:O14503 intact:EBI-9675596|uniprotkb:O56230 intact:EBI-711810|uniprotkb:Q96TD3|ensembl:ENSP00000256495 psi-mi:rex_htl1c(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-1(gene name synonym)|uniprotkb:p27Rex(gene name synonym) psi-mi:bhe40_human(display_long)|uniprotkb:BHLHE40(gene name)|psi-mi:BHLHE40(display_short)|uniprotkb:Differentially expressed in chondrocytes protein 1(gene name synonym)|uniprotkb:Enhancer-of-split and hairy-related protein 2(gene name synonym)|uniprotkb:Stimulated by retinoic acid gene 13 protein(gene name synonym)|uniprotkb:BHLHB2(gene name synonym)|uniprotkb:DEC1(gene name synonym)|uniprotkb:SHARP2(gene name synonym)|uniprotkb:STRA13(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676654|imex:IM-22977-200 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1EXY|refseq:NP_057863.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) ensembl:ENSG00000134107(gene)|ensembl:ENST00000256495(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016604"(nuclear body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043426"(MRF binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|refseq:NP_003661.1|dip:DIP-36698N|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:O14503|reactome:R-HSA-1368108 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:Jg3y2XqUP/JBerfBYcxMesTuQFQ11927 rogid:JZrZ1Yo2PF33s9Lf8rLTHCqoptk9606 intact-crc:F4B013C0E310FB85|rigid:ghLwRctQMwqQcdiD+Lnej6Zuh+w false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:O14595 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-2802973|uniprotkb:Q6NZY3|uniprotkb:Q9UEX1|uniprotkb:A8K5H4|uniprotkb:Q53ZR2|ensembl:ENSP00000381148 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:ctds2_human(display_long)|uniprotkb:NIF2(gene name synonym)|uniprotkb:OS4(gene name synonym)|uniprotkb:SCP2(gene name synonym)|uniprotkb:Nuclear LIM interactor-interacting factor 2(gene name synonym)|uniprotkb:Protein OS-4(gene name synonym)|uniprotkb:Small C-terminal domain phosphatase 2(gene name synonym)|uniprotkb:Small CTD phosphatase 2(gene name synonym)|uniprotkb:CTDSP2(gene name)|psi-mi:CTDSP2(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676664|imex:IM-22977-202 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_005721.3|interpro:IPR011948(Dullard-like phosphatase domain)|interpro:IPR023214|interpro:IPR036412|interpro:IPR040078|mint:O14595|rcsb pdb:2Q5E|reactome:R-HSA-381038|ensembl:ENSG00000175215(gene)|ensembl:ENST00000398073(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008420"(RNA polymerase II CTD heptapeptide repeat phosphatase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR004274(NLI interacting factor)|dip:DIP-61245N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:aYyUZE/wrtAyE4rMDaGGO8pNkYw9606 intact-crc:CECDFF3396062A57|rigid:/M5HrXG7bQFk58qqPumO178/aCU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:Q9UI95 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-77889|ensembl:ENSP00000235310|ensembl:ENSP00000365855|ensembl:ENSP00000365882|uniprotkb:Q5TGW7|uniprotkb:Q9UNA7|uniprotkb:Q9Y6I6|uniprotkb:B3KNE3 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:md2l2_human(display_long)|uniprotkb:MAD2L2(gene name)|psi-mi:MAD2L2(display_short)|uniprotkb:MAD2B(gene name synonym)|uniprotkb:REV7(gene name synonym)|uniprotkb:Mitotic arrest deficient 2-like protein 2(gene name synonym)|uniprotkb:REV7 homolog(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676669|imex:IM-22977-203 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) ensembl:ENSG00000116670(gene)|ensembl:ENST00000235310(transcript)|ensembl:ENST00000376667(transcript)|ensembl:ENST00000376692(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007015"(actin filament organization)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0016035"(zeta DNA polymerase complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042772"(DNA damage response, signal transduction resulting in transcription)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR036570|rcsb pdb:3ABD|rcsb pdb:3ABE|rcsb pdb:3VU7|rcsb pdb:4EXT|rcsb pdb:4GK0|rcsb pdb:4GK5|rcsb pdb:5XPT|rcsb pdb:5XPU|rcsb pdb:6BC8|rcsb pdb:6BCD|rcsb pdb:6BI7|rcsb pdb:6K07|rcsb pdb:6K08|rcsb pdb:6KEA|rcsb pdb:6KTO|rcsb pdb:6M7A|rcsb pdb:6M7B|rcsb pdb:6NIF|rcsb pdb:6VE5|rcsb pdb:6WS0|rcsb pdb:6WS5|rcsb pdb:6WW9|rcsb pdb:6WWA|rcsb pdb:7L9P|reactome:R-HSA-110312|reactome:R-HSA-5655862|reactome:R-HSA-5656121|refseq:NP_001120797.1|refseq:NP_006332.3|refseq:XP_011538809.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:KBeawMhcP3iXUel74pUDl85A/vw9606 intact-crc:A9B9515CC1D1E3DD|rigid:AQVllxvjOHfIELZFBe7Hetk+tWo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q5T8I9 uniprotkb:P14079 intact:EBI-9675710|uniprotkb:Q96NN0|uniprotkb:B1AM16|uniprotkb:B1AM17|uniprotkb:Q96EJ7|uniprotkb:A8MRR6|ensembl:ENSP00000359049|ensembl:ENSP00000385655|ensembl:ENSP00000499017 intact:EBI-9675698|uniprotkb:O56231 psi-mi:henmt_human(display_long)|uniprotkb:HENMT1(gene name)|psi-mi:HENMT1(display_short)|uniprotkb:C1orf59(gene name synonym)|uniprotkb:HEN1 methyltransferase homolog 1(gene name synonym) psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676674|imex:IM-22977-204 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001096062.1|refseq:NP_653185.2|ensembl:ENSG00000162639(gene)|ensembl:ENST00000370032(transcript)|ensembl:ENST00000402983(transcript)|ensembl:ENST00000651461(transcript)|go:"GO:0001510"(RNA methylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008171"(O-methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0034587"(piRNA metabolic process)|go:"GO:0043186"(P granule)|go:"GO:0046872"(metal ion binding)|go:"GO:0090486"(small RNA 2'-O-methyltransferase)|interpro:IPR026610|interpro:IPR029063|rcsb pdb:4XCX|rcsb pdb:5WY0|reactome:R-HSA-5601884 interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:UXyyHUVxIewQH/NZwBful5PQcvc9606 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 intact-crc:4A71D85353399CCC|rigid:Y+xqm/GixGdNWYkZ1cq8BBVqe7k false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C206 uniprotkb:O75928 intact:EBI-9675596|uniprotkb:O56230 intact:EBI-348555|uniprotkb:O75927|uniprotkb:Q96BT5|uniprotkb:Q96KE3|ensembl:ENSP00000465676 psi-mi:rex_htl1c(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-1(gene name synonym)|uniprotkb:p27Rex(gene name synonym) psi-mi:pias2_human(display_long)|uniprotkb:Protein inhibitor of activated STAT x(gene name synonym)|uniprotkb:Msx-interacting zinc finger protein(gene name synonym)|uniprotkb:DAB2-interacting protein(gene name synonym)|uniprotkb:Androgen receptor-interacting protein 3(gene name synonym)|uniprotkb:PIAS-NY protein(gene name synonym)|uniprotkb:PIAS2(gene name)|psi-mi:PIAS2(display_short)|uniprotkb:Protein inhibitor of activated STAT2(gene name synonym)|uniprotkb:PIASX(gene name synonym)|uniprotkb:E3 SUMO-protein transferase PIAS2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676659|imex:IM-22977-201 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1EXY|refseq:NP_057863.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) refseq:NP_004662.2|refseq:NP_775298.1|refseq:NP_001310989.1|ensembl:ENSG00000078043(gene)|ensembl:ENST00000585916(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023321|interpro:IPR027228|interpro:IPR036361|interpro:IPR038654|mint:O75928|rcsb pdb:2ASQ|rcsb pdb:4FO9|reactome:R-HSA-3108214|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-4090294 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:Jg3y2XqUP/JBerfBYcxMesTuQFQ11927 rogid:/7gObRzCbafNTNMKe8leGG/h2NQ9606 intact-crc:F4B3459F17E681C3|rigid:gBuzMlGhQBqSDVhh2EIOpj6h0bc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:Q8WW34 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-9675724|uniprotkb:Q5JY54|uniprotkb:Q6ZU23|ensembl:ENSP00000354312 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:tm239_human(display_long)|uniprotkb:TMEM239(gene name)|psi-mi:TMEM239(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676679|imex:IM-22977-205 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_001305136.1|refseq:XP_011527431.1|refseq:NP_001161142.1|ensembl:ENSG00000198326(gene)|ensembl:ENST00000361033(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR031694 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:/IAp0KVUESWppSZWM55RQ+08om09606 intact-crc:5A1554BE1C6B1D65|rigid:lazUsuvTmR9UCvjhtsXBj5ny5YA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:O43186 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-748171|uniprotkb:Q0QD45|ensembl:ENSP00000221996|ensembl:ENSP00000445565 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:crx_human(display_long)|uniprotkb:CRX(gene name)|psi-mi:CRX(display_short)|uniprotkb:CORD2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676684|imex:IM-22977-206 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_000545.1|ensembl:ENSG00000105392(gene)|ensembl:ENST00000221996(transcript)|ensembl:ENST00000539067(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050896"(response to stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:v/bkO/0iLzq1Q2HtieWQQ40RF9M9606 intact-crc:B6C12B030C0B6AFC|rigid:FuKIZMUGNIJ0P4hSi3/FF++Rvh4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:Q8N4L8 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-1104933|ensembl:ENSP00000361392|uniprotkb:Q6RWT2 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:ccd24_human(display_long)|uniprotkb:CCDC24(gene name)|psi-mi:CCDC24(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676689|imex:IM-22977-207 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) ensembl:ENSG00000159214(gene)|ensembl:ENST00000372318(transcript)|go:"GO:0001835"(blastocyst hatching)|interpro:IPR031367|refseq:NP_689712.1|refseq:XP_016855930.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:+WHY6f4VV8Z2uvuWOUYqOSCN36o9606 intact-crc:28F1B1C55901572C|rigid:CTvhQm5xMNVUURO/CBaTiM24ZHg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:Q6PF05 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-8656864|ensembl:ENSP00000422188|uniprotkb:Q96LJ2|intact:MINT-8163808|uniprotkb:Q6RGS4|uniprotkb:Q8N7R3|uniprotkb:G8IJH6 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:tt23l_human(display_long)|uniprotkb:TTC23L(gene name)|psi-mi:TTC23L(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676694|imex:IM-22977-208 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) ensembl:ENSG00000205838(gene)|ensembl:ENST00000505624(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0030496"(midbody)|go:"GO:0034976"(response to endoplasmic reticulum stress)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR042621|mint:Q6PF05|refseq:NP_001304878.1|refseq:NP_653326.3 psi-mi:"MI:0471"(mint) - comment:mint figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:SRndoUysST7RgIovvs89vd30vMk9606 intact-crc:2AC9AA6EBDEB3A65|rigid:Tle3OnFVOzKeBMVeCotXaOD/ixI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:Q6NYC8 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-2557469|uniprotkb:A8MSS7|uniprotkb:Q8NDQ4|uniprotkb:A2AIB8|uniprotkb:Q9BRL9|uniprotkb:B7ZCV7|uniprotkb:Q8TF52|uniprotkb:Q6ZUJ6|uniprotkb:Q68CK8|uniprotkb:A4UBI6|uniprotkb:A6NCB7|uniprotkb:A2AB01|uniprotkb:Q6ZTV1|ensembl:ENSP00000274853|ensembl:ENSP00000373067|ensembl:ENSP00000382150|ensembl:ENSP00000383400|ensembl:ENSP00000388790|ensembl:ENSP00000400129|ensembl:ENSP00000400990|ensembl:ENSP00000404066|ensembl:ENSP00000405234|ensembl:ENSP00000412456|ensembl:ENSP00000413596|ensembl:ENSP00000416648|ensembl:ENSP00000480270 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:ppr18_human(display_long)|uniprotkb:PPP1R18(gene name)|psi-mi:PPP1R18(display_short)|uniprotkb:HKMT1098(gene name synonym)|uniprotkb:KIAA1949(gene name synonym)|uniprotkb:Protein phosphatase 1 F-actin cytoskeleton-targeting subunit(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 18(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676699|imex:IM-22977-209 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_001128342.1|refseq:NP_597728.1|ensembl:ENSG00000146112(gene)|ensembl:ENSG00000206485(gene)|ensembl:ENSG00000225060(gene)|ensembl:ENSG00000229998(gene)|ensembl:ENST00000274853(transcript)|ensembl:ENST00000383573(transcript)|ensembl:ENST00000399199(transcript)|ensembl:ENST00000400554(transcript)|ensembl:ENST00000437121(transcript)|ensembl:ENST00000438815(transcript)|ensembl:ENST00000438945(transcript)|ensembl:ENSG00000230341(gene)|ensembl:ENST00000443517(transcript)|ensembl:ENSG00000234000(gene)|ensembl:ENST00000444206(transcript)|ensembl:ENST00000449705(transcript)|ensembl:ENST00000451544(transcript)|ensembl:ENST00000455935(transcript)|ensembl:ENST00000615527(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0019902"(phosphatase binding)|interpro:IPR025903|interpro:IPR025907|interpro:IPR026671|mint:Q6NYC8 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:63zpNZuwQb7VD0pOrr6yaRpPNmA9606 intact-crc:9F20346323C4B635|rigid:tCmMeavhf6cC5sotfoHYwwQBlnY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:P43268 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-6447147|ensembl:ENSP00000321835|ensembl:ENSP00000377273|ensembl:ENSP00000465718|uniprotkb:B7Z5J3|uniprotkb:B7Z9J6|uniprotkb:Q96AW9|uniprotkb:A8K314 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:etv4_human(display_long)|uniprotkb:Adenovirus E1A enhancer-binding protein(gene name synonym)|uniprotkb:E1A-F(gene name synonym)|uniprotkb:E1AF(gene name synonym)|uniprotkb:PEA3(gene name synonym)|uniprotkb:Polyomavirus enhancer activator 3 homolog(gene name synonym)|uniprotkb:ETV4(gene name)|psi-mi:ETV4(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676704|imex:IM-22977-210 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) ensembl:ENSG00000175832(gene)|ensembl:ENST00000319349(transcript)|ensembl:ENST00000393664(transcript)|ensembl:ENST00000591713(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030154"(cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR006715(PEA3-type ETS-domain transcription factor, N-terminal)|interpro:IPR036388|interpro:IPR036390|rcsb pdb:4UUV|rcsb pdb:5ILU|reactome:R-HSA-5687128|rcsb pdb:4CO8|refseq:NP_001073143.1|refseq:NP_001248366.1|refseq:NP_001248367.1|refseq:NP_001977.1|refseq:NP_001248368.1|dip:DIP-748N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:9CuoBGjLzbo93LSm5yNFuBQlATg9606 intact-crc:2210089911BCB119|rigid:aSIvNfO1eP2MzxNUKXk5HD5e8uQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:Q9NP87 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-9675790|uniprotkb:Q86WQ9|uniprotkb:D3DVK4|uniprotkb:Q6P5X8|ensembl:ENSP00000242248 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:dpolm_human(display_long)|uniprotkb:POLM(gene name)|psi-mi:POLM(display_short)|uniprotkb:Terminal transferase(gene name synonym)|uniprotkb:polmu(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676739|imex:IM-22977-217 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_001271259.1|refseq:NP_001271260.1|refseq:NP_037416.1|rcsb pdb:6IPK|rcsb pdb:6IPL|rcsb pdb:6IPM|rcsb pdb:6IPN|rcsb pdb:6P1M|rcsb pdb:6P1N|rcsb pdb:6P1O|rcsb pdb:6P1P|rcsb pdb:6P1Q|rcsb pdb:6P1R|rcsb pdb:6P1S|rcsb pdb:6P1T|rcsb pdb:6P1U|rcsb pdb:6P1V|rcsb pdb:6P1W|rcsb pdb:6WIC|rcsb pdb:6WID|rcsb pdb:6WIE|rcsb pdb:7CO6|rcsb pdb:7CO8|rcsb pdb:7CO9|rcsb pdb:7COA|rcsb pdb:7COB|rcsb pdb:7COC|rcsb pdb:7COD|reactome:R-HSA-5693571|ensembl:ENSG00000122678(gene)|ensembl:ENST00000242248(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|interpro:IPR001357(BRCT)|interpro:IPR001726(DNA nucleotidylexotransferase)|interpro:IPR002054(DNA-directed DNA polymerase, family X)|interpro:IPR010996(DNA-directed DNA polymerase, family X, beta-like, N-terminal)|interpro:IPR018944|interpro:IPR019843|interpro:IPR022312|interpro:IPR027249|interpro:IPR027421|interpro:IPR028207|interpro:IPR029398|interpro:IPR036420|interpro:IPR037160|interpro:IPR043519|rcsb pdb:2DUN|rcsb pdb:2HTF|rcsb pdb:4LZD|rcsb pdb:4LZG|rcsb pdb:4M04|rcsb pdb:4M0A|rcsb pdb:4YCX|rcsb pdb:4YD1|rcsb pdb:4YD2|rcsb pdb:5TWP|rcsb pdb:5TWQ|rcsb pdb:5TWR|rcsb pdb:5TWS|rcsb pdb:5TXX|rcsb pdb:5TXZ|rcsb pdb:5TYB|rcsb pdb:5TYC|rcsb pdb:5TYD|rcsb pdb:5TYE|rcsb pdb:5TYF|rcsb pdb:5TYG|rcsb pdb:5TYU|rcsb pdb:5TYV|rcsb pdb:5TYW|rcsb pdb:5TYX|rcsb pdb:5TYY|rcsb pdb:5TYZ|rcsb pdb:5VZ7|rcsb pdb:5VZ8|rcsb pdb:5VZ9|rcsb pdb:5VZA|rcsb pdb:5VZB|rcsb pdb:5VZC|rcsb pdb:5VZD|rcsb pdb:5VZE|rcsb pdb:5VZF|rcsb pdb:5VZG|rcsb pdb:5VZH|rcsb pdb:5VZI|rcsb pdb:5W4F|rcsb pdb:5ZLC|rcsb pdb:6AEC|rcsb pdb:6AEH|rcsb pdb:6AK5|rcsb pdb:6AK6|rcsb pdb:6AK8|rcsb pdb:6AK9|rcsb pdb:6AKH|rcsb pdb:6IPD|rcsb pdb:6IPE|rcsb pdb:6IPF|rcsb pdb:6IPG|rcsb pdb:6IPH|rcsb pdb:6IPI|rcsb pdb:6IPJ psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:PjYb9sk0XvVaJwJ3JdGQY4IvenE9606 intact-crc:97C8FAAA374E3ECA|rigid:nZA7YVznR+9uH7ecylRKeQjBF8k false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:Q9H4K1 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-740128|uniprotkb:Q6ICD0|uniprotkb:Q9Y413|ensembl:ENSP00000483356|uniprotkb:A0A087X0F7 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:ribc2_human(display_long)|uniprotkb:RIBC2(gene name)|psi-mi:RIBC2(display_short)|uniprotkb:C22orf11(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676734|imex:IM-22977-216 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) ensembl:ENSG00000128408(gene)|ensembl:ENST00000614167(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR008805(RIB43A)|refseq:XP_005261581.1|refseq:NP_056468.3 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2019/11/14 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:rU6ggF8fZGGy7ICGFHxeMZQLkw49606 intact-crc:67F2A301BDF7C3EF|rigid:jBn3FS21nDC+gzVuol8QDxilLn4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:Q8IZQ1 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-1569256|uniprotkb:Q4W5K5|uniprotkb:Q6P0Q5|uniprotkb:Q8N1T2|uniprotkb:Q8NAV6|uniprotkb:Q96BS7|uniprotkb:Q96D33|uniprotkb:Q96N85|uniprotkb:Q9Y2J7|ensembl:ENSP00000295888 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:wdfy3_human(display_long)|uniprotkb:Autophagy-linked FYVE protein(gene name synonym)|uniprotkb:WDFY3(gene name)|psi-mi:WDFY3(display_short)|uniprotkb:KIAA0993(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676729|imex:IM-22977-215 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_055806.2|refseq:XP_011530065.1|refseq:XP_011530067.1|ensembl:ENSG00000163625(gene)|ensembl:ENST00000295888(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016605"(PML body)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035973"(aggrephagy)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR019775|interpro:IPR023362|interpro:IPR036322|interpro:IPR036372|mint:Q8IZQ1|rcsb pdb:3WIM|rcsb pdb:6W9N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:yVIfhD/TU9JhrQR8WCChT4Jpi8c9606 intact-crc:74F64550E7E84D0F|rigid:oCtNq/MukZ+J4BT1dPOIPMFLnno false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:Q8N448 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-2340947|uniprotkb:Q6ZMH2|uniprotkb:Q5W0P0|uniprotkb:Q96SH4|ensembl:ENSP00000325929|ensembl:ENSP00000497224 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:lnx2_human(display_long)|uniprotkb:LNX2(gene name)|psi-mi:LNX2(display_short)|uniprotkb:PDZRN1(gene name synonym)|uniprotkb:Numb-binding protein 2(gene name synonym)|uniprotkb:PDZ domain-containing RING finger protein 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676724|imex:IM-22977-214 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_699202.1|refseq:XP_016875923.1|ensembl:ENSG00000139517(gene)|ensembl:ENST00000316334(transcript)|ensembl:ENST00000649248(transcript)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036034|mint:Q8N448|rcsb pdb:2VWR|rcsb pdb:5DIN|rcsb pdb:5E11|rcsb pdb:5E1Y|rcsb pdb:5E21|rcsb pdb:5E22 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:cIS5t4XkbnIgelDlUc692nI285g9606 intact-crc:9504FE8ADC34E253|rigid:3kgPaEk7p/HZAs6GpyyrQsws0mg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:Q8N448 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-2340947|uniprotkb:Q6ZMH2|uniprotkb:Q5W0P0|uniprotkb:Q96SH4|ensembl:ENSP00000325929|ensembl:ENSP00000497224 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:lnx2_human(display_long)|uniprotkb:LNX2(gene name)|psi-mi:LNX2(display_short)|uniprotkb:PDZRN1(gene name synonym)|uniprotkb:Numb-binding protein 2(gene name synonym)|uniprotkb:PDZ domain-containing RING finger protein 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676719|imex:IM-22977-213 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_699202.1|refseq:XP_016875923.1|ensembl:ENSG00000139517(gene)|ensembl:ENST00000316334(transcript)|ensembl:ENST00000649248(transcript)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036034|mint:Q8N448|rcsb pdb:2VWR|rcsb pdb:5DIN|rcsb pdb:5E11|rcsb pdb:5E1Y|rcsb pdb:5E21|rcsb pdb:5E22 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:cIS5t4XkbnIgelDlUc692nI285g9606 intact-crc:ED08A763CBDC131D|rigid:3kgPaEk7p/HZAs6GpyyrQsws0mg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:Q01844 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-739737|uniprotkb:Q92635|uniprotkb:Q96FE8|uniprotkb:Q96MX4|uniprotkb:Q9BWA2|uniprotkb:Q5THL0|intact:EBI-28987207|ensembl:ENSP00000381031|intact:EBI-10985407|uniprotkb:B0QYK1|uniprotkb:Q96MN4 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:ews_human(display_long)|uniprotkb:EWSR1(gene name)|psi-mi:EWSR1(display_short)|uniprotkb:EWS(gene name synonym)|uniprotkb:EWS oncogene(gene name synonym)|uniprotkb:Ewing sarcoma breakpoint region 1 protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676709|imex:IM-22977-211 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_001156757.1|refseq:NP_005234.1|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q01844|rcsb pdb:2CPE|interpro:IPR001876(Zinc finger, RanBP2-type)|ensembl:ENSG00000182944(gene)|ensembl:ENST00000397938(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001156759.1|refseq:NP_053733.2|refseq:NP_001156758.1|ensembl:ENST00000332035|ensembl:ENSP00000331699|ensembl:ENST00000333395|ensembl:ENSP00000327456|ensembl:ENSP00000381031|ensembl:ENST00000406548|ensembl:ENSP00000385726|ensembl:ENST00000414183|ensembl:ENSP00000400142|dip:DIP-34449N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:7PxoTjcmcdUA3clzf0eW+iCFaS49606 intact-crc:5B922AD7F94F9958|rigid:W1Y++AnlhlHy57P93jLHoPiQVx8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:O15287 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-81610|ensembl:ENSP00000367910 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:fancg_human(display_long)|uniprotkb:FANCG(gene name)|psi-mi:FANCG(display_short)|uniprotkb:XRCC9(gene name synonym)|uniprotkb:DNA repair protein XRCC9(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676714|imex:IM-22977-212 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) ensembl:ENSG00000221829(gene)|refseq:NP_004620.1|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007286"(spermatid development)|go:"GO:0009314"(response to radiation)|ensembl:ENST00000378643(transcript)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0043240"(Fanconi anaemia nuclear complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039684|mint:O15287|rcsb pdb:7KZP|rcsb pdb:7KZQ|go:"GO:0001541"(ovarian follicle development)|rcsb pdb:7KZR|go:"GO:0003684"(damaged DNA binding)|rcsb pdb:7KZS|go:"GO:0005654"(nucleoplasm)|rcsb pdb:7KZT|rcsb pdb:7KZV|reactome:R-HSA-6783310|go:"GO:0005730"(nucleolus) psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:jVGeic2vn/qrZgro3IKXWhNteHo9606 intact-crc:CECD098B975A4B57|rigid:VUsCUWR++GF76Fc8mT3LpR/eMV0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:P07196 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-475646|uniprotkb:Q16154|uniprotkb:B9ZVN2|uniprotkb:Q8IU72|ensembl:ENSP00000482169 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:nfl_human(display_long)|uniprotkb:Neurofilament triplet L protein(gene name synonym)|uniprotkb:68 kDa neurofilament protein(gene name synonym)|uniprotkb:NEFL(gene name)|psi-mi:NEFL(display_short)|uniprotkb:NF68(gene name synonym)|uniprotkb:NFL(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676779|imex:IM-22977-225 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_006149.2|ensembl:ENSG00000277586(gene)|ensembl:ENST00000610854(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005883"(neurofilament)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031133"(regulation of axon diameter)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0030426"(growth cone)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045105"(intermediate filament polymerization or depolymerization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051258"(protein polymerization)|go:"GO:0051412"(response to corticosterone)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0060074"(synapse maturation)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:0099182"(presynaptic intermediate filament cytoskeleton)|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton)|go:"GO:1903935"(response to sodium arsenite)|go:"GO:1903937"(response to acrylamide)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027692|interpro:IPR039008|mint:P07196|reactome:R-HSA-438066|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:tgdjWnqcql4YMbd89ujbDoqN/Yg9606 intact-crc:92512B786CE70675|rigid:6OwJJGC5AlyUzGbTEhKg6wK+2uc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:Q6PEX3 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-3957672|ensembl:ENSP00000353742|uniprotkb:B0RZD3 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:kr261_human(display_long)|uniprotkb:KRTAP26-1(gene name)|psi-mi:KRTAP26-1(display_short)|uniprotkb:KAP26.1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676774|imex:IM-22977-224 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) ensembl:ENSG00000197683(gene)|ensembl:ENST00000360542(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|interpro:IPR007951(PMG)|reactome:R-HSA-6805567|refseq:NP_981950.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:VKgQPRg2qO2FXQx0fQ/dd/5kMws9606 intact-crc:2A6EE4ED18CEE70F|rigid:+5jUHKk7X2WXFr/jH8bKukyHA9c false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:P19012 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676769|imex:IM-22977-223 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606 intact-crc:B25686770380AEE7|rigid:RR3ow1wldjtVSxYngkmxlWNhEyM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:P05787 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-297852|uniprotkb:Q14099|uniprotkb:Q14716|uniprotkb:Q14717|uniprotkb:Q53GJ0|uniprotkb:Q6DHW5|uniprotkb:Q6GMY0|uniprotkb:Q6P4C7|uniprotkb:Q96J60|ensembl:ENSP00000293308|ensembl:ENSP00000447402|ensembl:ENSP00000447566|uniprotkb:A8K4H3|uniprotkb:B0AZN5|uniprotkb:F8VXB4 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:k2c8_human(display_long)|uniprotkb:Keratin-8(gene name synonym)|uniprotkb:KRT8(gene name)|psi-mi:KRT8(display_short)|uniprotkb:CYK8(gene name synonym)|uniprotkb:Cytokeratin-8(gene name synonym)|uniprotkb:Type-II keratin Kb8(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676764|imex:IM-22977-222 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_001243222.1|ensembl:ENSG00000170421(gene)|ensembl:ENST00000293308(transcript)|ensembl:ENST00000546897(transcript)|ensembl:ENST00000552551(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005911"(cell-cell junction)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030018"(Z disc)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045095"(keratin filament)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051599"(response to hydrostatic pressure)|go:"GO:0051707"(response to other organism)|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097284"(hepatocyte apoptotic process)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|mint:P05787|reactome:R-HSA-6805567|reactome:R-HSA-6809371|refseq:NP_002264.1|dip:DIP-424N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:zyV8eOjx426ehjJYK4jsizORUws9606 intact-crc:EA5D098A01BF353B|rigid:x7czc5DkQYDo3LHUx9TWiA9EhDY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:P02538 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-702198|uniprotkb:P48667|uniprotkb:Q08AR4|uniprotkb:Q6NT67|uniprotkb:Q96CL4|uniprotkb:A4QPC1|ensembl:ENSP00000369317 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:k2c6a_human(display_long)|uniprotkb:Cytokeratin-6A(gene name synonym)|uniprotkb:Keratin-6A(gene name synonym)|uniprotkb:Cytokeratin-6D(gene name synonym)|uniprotkb:KRT6A(gene name)|psi-mi:KRT6A(display_short)|uniprotkb:K6A(gene name synonym)|uniprotkb:KRT6D(gene name synonym)|uniprotkb:Type-II keratin Kb6(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676759|imex:IM-22977-221 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_005545.1|dip:DIP-533N|ensembl:ENSG00000205420(gene)|ensembl:ENST00000330722(transcript)|go:"GO:0001899"(negative regulation of cytolysis by symbiont of host cells)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0042060"(wound healing)|go:"GO:0045095"(keratin filament)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051838"(cytolysis by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000536"(negative regulation of entry of bacterium into host cell)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|mint:P02538|rcsb pdb:5KI0|reactome:R-HSA-6805567|reactome:R-HSA-6809371 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:feIxUFTSMnjattUda5vdGhiL9H89606 intact-crc:EA5FB1F35D1D123B|rigid:apTyTuUgTkDGDy+Rz4ocMLr+PHc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:P19013 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-2371606|uniprotkb:Q6GTR8|uniprotkb:Q96LA7|uniprotkb:Q9BTL1|intact:EBI-22121113|uniprotkb:B4DRS2|uniprotkb:F8VS64|intact:EBI-22010019|intact:EBI-28973341|ensembl:ENSP00000448220 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:k2c4_human(display_long)|uniprotkb:KRT4(gene name)|psi-mi:KRT4(display_short)|uniprotkb:CYK4(gene name synonym)|uniprotkb:Cytokeratin-4(gene name synonym)|uniprotkb:Keratin-4(gene name synonym)|uniprotkb:Type-II keratin Kb4(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676754|imex:IM-22977-220 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) ensembl:ENSP00000448220|refseq:NP_002263.3|ensembl:ENSG00000170477(gene)|ensembl:ENST00000551956(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0009986"(cell surface)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0045095"(keratin filament)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|mint:P19013|reactome:R-HSA-6805567|reactome:R-HSA-6809371 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2020/03/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:WBLRjdlqvNYbC7R2ZSNON6QLcOU9606 intact-crc:1BDE50859156F59D|rigid:Wnd+0bdcXFGiZEIPOUvcc1+px8U false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6PF18 uniprotkb:P14079 intact:EBI-9675802|uniprotkb:Q86YQ9|ensembl:ENSP00000347486 intact:EBI-9675698|uniprotkb:O56231 psi-mi:morn3_human(display_long)|uniprotkb:MORN3(gene name)|psi-mi:MORN3(display_short) psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676744|imex:IM-22977-218 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_776254.3|refseq:XP_005253926.1|refseq:XP_011536515.1|ensembl:ENSG00000139714(gene)|ensembl:ENST00000355329(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR003409(MORN motif) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:DqvOxujxoozjpdQzRPQrZurWHY09606 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 intact-crc:BA6AE5481E5F578D|rigid:NI6zQlnJDA+4KGe0fV628ScgQbg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:P17482 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-745290|uniprotkb:Q9H1I1|uniprotkb:B2RDB7|ensembl:ENSP00000309439 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:hxb9_human(display_long)|uniprotkb:Homeobox protein Hox-2E(gene name synonym)|uniprotkb:Homeobox protein Hox-2.5(gene name synonym)|uniprotkb:HOXB9(gene name)|psi-mi:HOXB9(display_short)|uniprotkb:HOX2E(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676749|imex:IM-22977-219 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_076922.1|ensembl:ENSG00000170689(gene)|ensembl:ENST00000311177(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0030879"(mammary gland development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006711(Hox9 activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017112(Homeobox, Hox9)|interpro:IPR017970|interpro:IPR020479|mint:P17482 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:1pOMN5hO0W2eq4PII7uRN7EZ7DY9606 intact-crc:A86FDB92D0F0059F|rigid:oY0MEygEOSObMcI0BiNFhUcwoAI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P29474 uniprotkb:P14079 intact:EBI-1391623|uniprotkb:A0S0A7|uniprotkb:E9PFR2|uniprotkb:Q13662|uniprotkb:Q14251|uniprotkb:Q14434|uniprotkb:Q6GSL5|uniprotkb:A8KA63|uniprotkb:B2RCQ1|uniprotkb:Q548C1|uniprotkb:Q9UDC6|uniprotkb:A0S0A8|ensembl:ENSP00000297494 intact:EBI-9675698|uniprotkb:O56231 psi-mi:nos3_human(display_long)|uniprotkb:Endothelial NOS(gene name synonym)|uniprotkb:EC-NOS(gene name synonym)|uniprotkb:NOS type III(gene name synonym)|uniprotkb:Constitutive NOS(gene name synonym)|uniprotkb:NOS3(gene name)|psi-mi:NOS3(display_short) psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676789|imex:IM-22977-227 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000594.2|refseq:NP_001153581.1|refseq:NP_001153582.1|refseq:NP_001153583.1|refseq:XP_016867721.1|dip:DIP-38479N|ensembl:ENSG00000164867(gene)|go:"GO:0034405"(response to fluid shear stress)|go:"GO:0034617"(tetrahydrobiopterin binding)|go:"GO:0034618"(arginine binding)|go:"GO:0042311"(vasodilation)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050661"(NADP binding)|go:"GO:0070168"(negative regulation of biomineral tissue development)|go:"GO:0097746"(blood vessel diameter maintenance)|ensembl:ENST00000297494(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003100"(regulation of systemic arterial blood pressure by endothelin)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003184"(pulmonary valve morphogenesis)|go:"GO:0003203"(endocardial cushion morphogenesis)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004517"(nitric-oxide synthase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006527"(arginine catabolic process)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007263"(nitric oxide mediated signal transduction)|interpro:IPR001094(Flavodoxin-like)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR004030(Nitric oxide synthase, oxygenase region)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR012144(Nitric-oxide synthase)|interpro:IPR017927|interpro:IPR017938|interpro:IPR023173|interpro:IPR029039|interpro:IPR036119|interpro:IPR039261|mint:P29474|rcsb pdb:1M9J|rcsb pdb:1M9K|rcsb pdb:1M9M|rcsb pdb:1M9Q|rcsb pdb:1M9R|rcsb pdb:1NIW|rcsb pdb:2LL7|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0009725"(response to hormone)|go:"GO:0010181"(FMN binding)|go:"GO:0010544"(negative regulation of platelet activation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014740"(negative regulation of muscle hyperplasia)|go:"GO:0014806"(smooth muscle hyperplasia)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0020037"(heme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031284"(positive regulation of guanylate cyclase activity)|go:"GO:0031644"(regulation of nervous system process)|go:"GO:0032496"(response to lipopolysaccharide)|rcsb pdb:2MG5|rcsb pdb:2N8J|rcsb pdb:3EAH|rcsb pdb:3NOS|rcsb pdb:4D1O|rcsb pdb:4D1P|rcsb pdb:5UO8|rcsb pdb:5UO9|rcsb pdb:5UOA|rcsb pdb:5UOB|rcsb pdb:5UOC|rcsb pdb:5VVB|rcsb pdb:5VVC|rcsb pdb:5VVD|rcsb pdb:5XOF|rcsb pdb:6AV6|rcsb pdb:6AV7|rcsb pdb:6CIE|rcsb pdb:6CIF|rcsb pdb:6NH1|rcsb pdb:6NH2|rcsb pdb:6NH3|rcsb pdb:6NH4|rcsb pdb:6NH5|rcsb pdb:6NH6|rcsb pdb:6NH7|rcsb pdb:6NH8|rcsb pdb:6NHF|rcsb pdb:6POU|rcsb pdb:6POV|rcsb pdb:6POW|rcsb pdb:6POX|rcsb pdb:6POY|rcsb pdb:6POZ|rcsb pdb:6PP0|rcsb pdb:6PP1|rcsb pdb:6PP2|rcsb pdb:6PP3|rcsb pdb:6PP4|reactome:R-HSA-1222556|reactome:R-HSA-1474151|reactome:R-HSA-203615|reactome:R-HSA-203641|reactome:R-HSA-203754|reactome:R-HSA-392154|reactome:R-HSA-5218920|reactome:R-HSA-9009391 interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2018/04/06 rogid:FIvVY2y5ltfs8KVWaMEHCEt2pMk9606 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 intact-crc:37F6E1AA5D12A138|rigid:EjPL/4tW1FuddaOPDoXBHt3D6NE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9P2K5 uniprotkb:P14079 intact:EBI-9675857|uniprotkb:A7MCZ9|uniprotkb:C9K0J4|uniprotkb:Q9NUQ1|uniprotkb:Q7Z4B7|uniprotkb:C9J921|uniprotkb:Q6NUM5|uniprotkb:Q9H922|uniprotkb:Q7L388 intact:EBI-9675698|uniprotkb:O56231 psi-mi:myef2_human(display_long)|uniprotkb:MYEF2(gene name)|psi-mi:MYEF2(display_short)|uniprotkb:KIAA1341(gene name synonym)|uniprotkb:MST156(gene name synonym) psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676794|imex:IM-22977-228 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_057216.2|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:Q9P2K5|refseq:NP_001288139.1|interpro:IPR034630|interpro:IPR034631|interpro:IPR034632|interpro:IPR035979|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0014902"(myotube differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000815"(regulation of mRNA stability involved in response to oxidative stress) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:v/dNVOlL/ndJDraGpMrPedvq/FU9606 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 intact-crc:C15013E0E7DD11C0|rigid:/kF/tDcEfmVod4PyGORbmdQpgCc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:Q9UK41 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-727424|uniprotkb:Q86VK0|ensembl:ENSP00000292510|ensembl:ENSP00000434064|ensembl:ENSP00000496519|ensembl:ENSP00000496693 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:vps28_human(display_long)|uniprotkb:VPS28(gene name)|psi-mi:VPS28(display_short)|uniprotkb:ESCRT-I complex subunit VPS28(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676799|imex:IM-22977-229 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_057292.1|refseq:NP_898880.1|ensembl:ENSG00000160948(gene)|ensembl:ENSG00000285339(gene)|ensembl:ENST00000292510(transcript)|ensembl:ENST00000526054(transcript)|ensembl:ENST00000642867(transcript)|ensembl:ENST00000643186(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR007143(Vacuolar protein sorting-associated, VPS28)|interpro:IPR017898|interpro:IPR017899|interpro:IPR037202|interpro:IPR037206|interpro:IPR038358|mint:Q9UK41|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:GUcc7bRf1LaLklAYVLEHRSihPjA9606 intact-crc:91E6FCF062A47021|rigid:nhymNDABi2xc9Bnswb/HAVWosyE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:Q9BPX1 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-742664|uniprotkb:Q9UKU3|ensembl:ENSP00000263278 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:dhb14_human(display_long)|uniprotkb:DHRS10(gene name synonym)|uniprotkb:Dehydrogenase/reductase SDR family member 10(gene name synonym)|uniprotkb:17-beta-hydroxysteroid dehydrogenase DHRS10(gene name synonym)|uniprotkb:Retinal short-chain dehydrogenase/reductase retSDR3(gene name synonym)|uniprotkb:HSD17B14(gene name)|psi-mi:HSD17B14(display_short)|uniprotkb:SDR3(gene name synonym)|uniprotkb:SDR47C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 47C member 1(gene name synonym)|uniprotkb:UNQ502/PRO474(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676804|imex:IM-22977-230 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_057330.2|ensembl:ENSG00000087076(gene)|ensembl:ENST00000263278(transcript)|go:"GO:0004303"(estradiol 17-beta-dehydrogenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006706"(steroid catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047045"("testosterone 17-beta-dehydrogenase (NADP+) activity")|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|rcsb pdb:1YDE|rcsb pdb:5EN4|rcsb pdb:5HS6|rcsb pdb:5ICM|rcsb pdb:5ICS|rcsb pdb:5JS6|rcsb pdb:5JSF|rcsb pdb:5L7T|rcsb pdb:5L7W|rcsb pdb:5L7Y|rcsb pdb:5O42|rcsb pdb:5O43|rcsb pdb:5O6O|rcsb pdb:5O6X|rcsb pdb:5O6Z|rcsb pdb:5O72|rcsb pdb:5O7C|rcsb pdb:6EMM|rcsb pdb:6FFB|rcsb pdb:6G4L|rcsb pdb:6GBT|rcsb pdb:6GTB|rcsb pdb:6GTU|rcsb pdb:6H0M|rcsb pdb:6HNO|rcsb pdb:6QCK|rcsb pdb:6ZDE|rcsb pdb:6ZDI|reactome:R-HSA-193144 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:/t03kHO/EWlqKNv7+TkWbTV9jpM9606 intact-crc:E7BBD616E92A2B8F|rigid:O0MxVr8hCLOVRXTikI9Ms/s4NVc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:Q9NZD8 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-742688|uniprotkb:B4DW44|uniprotkb:Q6ZMB6|ensembl:ENSP00000204566|ensembl:ENSP00000404111 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:spg21_human(display_long)|uniprotkb:Spastic paraplegia 21 autosomal recessive Mast syndrome protein(gene name synonym)|uniprotkb:Acid cluster protein 33(gene name synonym)|uniprotkb:SPG21(gene name)|psi-mi:SPG21(display_short)|uniprotkb:ACP33(gene name synonym)|uniprotkb:BM-019(orf name)|uniprotkb:GL010(orf name)|uniprotkb:Spastic paraplegia 21 protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676809|imex:IM-22977-231 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_001121361.1|refseq:NP_001121362.1|refseq:NP_057714.1|ensembl:ENSG00000090487(gene)|ensembl:ENST00000204566(transcript)|ensembl:ENST00000433215(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR026151|interpro:IPR029058|mint:Q9NZD8|refseq:XP_005254494.1|refseq:XP_016877786.1|refseq:XP_016877787.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:MoKySBpEYFNm7Lox/HM5nnkmhkA9606 intact-crc:290EDD6A08C855BE|rigid:0JtDal2rUCd9gNxrsnD2qQXZftU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:P07196 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-475646|uniprotkb:Q16154|uniprotkb:B9ZVN2|uniprotkb:Q8IU72|ensembl:ENSP00000482169 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:nfl_human(display_long)|uniprotkb:Neurofilament triplet L protein(gene name synonym)|uniprotkb:68 kDa neurofilament protein(gene name synonym)|uniprotkb:NEFL(gene name)|psi-mi:NEFL(display_short)|uniprotkb:NF68(gene name synonym)|uniprotkb:NFL(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676784|imex:IM-22977-226 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_006149.2|ensembl:ENSG00000277586(gene)|ensembl:ENST00000610854(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005883"(neurofilament)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031133"(regulation of axon diameter)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0030426"(growth cone)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045105"(intermediate filament polymerization or depolymerization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051258"(protein polymerization)|go:"GO:0051412"(response to corticosterone)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0060074"(synapse maturation)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:0099182"(presynaptic intermediate filament cytoskeleton)|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton)|go:"GO:1903935"(response to sodium arsenite)|go:"GO:1903937"(response to acrylamide)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027692|interpro:IPR039008|mint:P07196|reactome:R-HSA-438066|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:tgdjWnqcql4YMbd89ujbDoqN/Yg9606 intact-crc:EA5D72917B0FF73B|rigid:6OwJJGC5AlyUzGbTEhKg6wK+2uc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:Q9P0T4 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-745520|uniprotkb:B2RDM6|ensembl:ENSP00000270451|ensembl:ENSP00000466047|ensembl:ENSP00000466564 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:zn581_human(display_long)|uniprotkb:ZNF581(gene name)|psi-mi:ZNF581(display_short)|uniprotkb:HSPC189(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676819|imex:IM-22977-233 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_057619.1|ensembl:ENSG00000171425(gene)|ensembl:ENST00000270451(transcript)|ensembl:ENST00000587252(transcript)|ensembl:ENST00000588537(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9P0T4|go:"GO:0005634"(nucleus)|refseq:XP_006723303.1|refseq:XP_016882356.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:SpE0ZPhcfXB4PnyufoyWq4iNAs89606 intact-crc:39A24CD65A35172D|rigid:OirJ8/gCqK7sI2xk3QhYekBrmTQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:Q969H6 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-366525|uniprotkb:Q53FS5|uniprotkb:Q9Y2Q6|uniprotkb:A6NL80|ensembl:ENSP00000350098 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:pop5_human(display_long)|uniprotkb:POP5(gene name)|psi-mi:POP5(display_short)|uniprotkb:AD-008(orf name)|uniprotkb:HSPC004(orf name)|uniprotkb:x0003(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676814|imex:IM-22977-232 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_057002.2|refseq:NP_937845.1|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|interpro:IPR002759(Ribonuclease P-related)|interpro:IPR016819(Ribonuclease P/MRP protein, subunit Pop5)|interpro:IPR038085|rcsb pdb:6AHR|rcsb pdb:6AHU|reactome:R-HSA-6784531|ensembl:ENSG00000167272(gene)|ensembl:ENST00000357500(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0005730"(nucleolus) psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:WYNesu92ICtpEM2lwO63c6hjcMY9606 intact-crc:A55ACFF09505B284|rigid:7kmKU2Wq9Vx9Pjq7tIQ45iPlo3g false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:Q9NX63 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-743375|ensembl:ENSP00000262570 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:mic19_human(display_long)|uniprotkb:CHCHD3(gene name)|psi-mi:CHCHD3(display_short)|uniprotkb:MINOS3(gene name synonym)|uniprotkb:Coiled-coil-helix-coiled-coil-helix domain-containing protein 3(gene name synonym)|uniprotkb:MIC19(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676824|imex:IM-22977-234 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) go:"GO:0008053"(mitochondrial fusion)|refseq:NP_060282.1|refseq:NP_001304106.1|ensembl:ENSG00000106554(gene)|ensembl:ENST00000262570(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0042407"(cristae formation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061617"(MICOS complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140275"(MIB complex)|mint:Q9NX63|reactome:R-HSA-1268020|reactome:R-HSA-8949613|go:"GO:0019902"(phosphatase binding) psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:Ox0+PoTPYwxw8cKNqpzvSCg+Smg9606 intact-crc:D56B75BADE5FCD40|rigid:KVsO9LcpE80tfk+Oojaewfgh4zo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:P25786 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-359352|uniprotkb:Q9BRV9|uniprotkb:A8K400|uniprotkb:Q53YE8|ensembl:ENSP00000379676 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:psa1_human(display_long)|uniprotkb:PSMA1(gene name)|psi-mi:PSMA1(display_short)|uniprotkb:PROS30(gene name synonym)|uniprotkb:PSC2(gene name synonym)|uniprotkb:Proteasome component C2(gene name synonym)|uniprotkb:Macropain subunit C2(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C2(gene name synonym)|uniprotkb:Proteasome nu chain(gene name synonym)|uniprotkb:30 kDa prosomal protein(gene name synonym)|uniprotkb:HC2(gene name synonym)|uniprotkb:NU(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676829|imex:IM-22977-235 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_002777.1|refseq:NP_683877.1|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000129084(gene)|ensembl:ENST00000396394(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0003723"(RNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0005844"(polysome)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|mint:P25786|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|dip:DIP-29369N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:tAADzZ1G9E/0BBeS8vybNx97v7k9606 intact-crc:855F020F6EB58428|rigid:G3NxB9GjJ3j72vMre9Ne9XlZ57c false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A8K1J0 uniprotkb:P14079 intact:EBI-9675917 intact:EBI-9675698|uniprotkb:O56231 psi-mi:a8k1j0_human(display_long) psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676839|imex:IM-22977-237 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR035175 interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:vDMi5ExMRZu+QfhPYYmxG+0DwB09606 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 intact-crc:AAEC70349354F7FE|rigid:a0hKMu4AEvDtrDWELOlxh0WbWnc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:Q9NSA3 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-747082|ensembl:ENSP00000366466|ensembl:ENSP00000366468|ensembl:ENSP00000366474|ensembl:ENSP00000383696|uniprotkb:Q5T4V2 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:cnbp1_human(display_long)|uniprotkb:Inhibitor of beta-catenin and Tcf-4(gene name synonym)|uniprotkb:CTNNBIP1(gene name)|psi-mi:CTNNBIP1(display_short)|uniprotkb:ICAT(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676834|imex:IM-22977-236 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_001012329.1|refseq:NP_064633.1|ensembl:ENSG00000178585(gene)|ensembl:ENST00000377256(transcript)|ensembl:ENST00000377258(transcript)|ensembl:ENST00000377263(transcript)|ensembl:ENST00000400904(transcript)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0002528"(regulation of vascular permeability involved in acute inflammatory response)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0060633"(negative regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0072201"(negative regulation of mesenchymal cell proliferation)|interpro:IPR009428(Beta-catenin-interacting ICAT)|interpro:IPR036911|interpro:IPR042999|rcsb pdb:1LUJ|rcsb pdb:1M1E|rcsb pdb:1T08|reactome:R-HSA-3769402|refseq:XP_016857342.1|refseq:XP_016857343.1|refseq:XP_016857344.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:+u/qGVFIboIBdcxthYr2OA1US3w9606 intact-crc:B6633F892C28928E|rigid:nMufRz+/oZeA/YhH5H5XJk5Zlyg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:Q9BV90 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-9675976|uniprotkb:Q1W6H3|uniprotkb:Q6IEF8|uniprotkb:Q9H5W4|ensembl:ENSP00000372482 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:snr25_human(display_long)|uniprotkb:SNRNP25(gene name)|psi-mi:SNRNP25(display_short)|uniprotkb:C16orf33(gene name synonym)|uniprotkb:Minus-99 protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676879|imex:IM-22977-245 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_078847.1|ensembl:ENSG00000161981(gene)|ensembl:ENST00000383018(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0045171"(intercellular bridge)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR039690|interpro:IPR040610|reactome:R-HSA-72165 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:B7etUEbENf9LDAcnXK/Qy0rc4/k9606 intact-crc:C3F9C2B6A36FFA55|rigid:Hnorz5WAkw+fAt5QrEgcyLKO46w false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:Q96BZ8 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-726510|uniprotkb:Q9HCU7|ensembl:ENSP00000222224|ensembl:ENSP00000477607|ensembl:ENSP00000478485|ensembl:ENSP00000479538|ensembl:ENSP00000480516|ensembl:ENSP00000481079|ensembl:ENSP00000481252|ensembl:ENSP00000481386|ensembl:ENSP00000481948|ensembl:ENSP00000483164 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:leng1_human(display_long)|uniprotkb:LENG1(gene name)|psi-mi:LENG1(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676874|imex:IM-22977-244 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_077292.2|ensembl:ENSG00000105617(gene)|ensembl:ENSG00000275935(gene)|ensembl:ENSG00000276628(gene)|ensembl:ENSG00000276774(gene)|ensembl:ENSG00000277457(gene)|ensembl:ENSG00000277808(gene)|ensembl:ENSG00000278257(gene)|ensembl:ENSG00000278426(gene)|ensembl:ENSG00000278516(gene)|ensembl:ENST00000222224(transcript)|ensembl:ENST00000610998(transcript)|ensembl:ENST00000613622(transcript)|ensembl:ENST00000614037(transcript)|ensembl:ENST00000616103(transcript)|ensembl:ENST00000616816(transcript)|ensembl:ENST00000617592(transcript)|ensembl:ENST00000619669(transcript)|ensembl:ENST00000621285(transcript)|ensembl:ENST00000621927(transcript)|interpro:IPR019339|interpro:IPR039875|ensembl:ENSG00000276959(gene) psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:CbwywThJZ/wcqO76EMhiG8tvJN09606 intact-crc:322E1358F387329A|rigid:8MajMyBcnvMsy1teFd1rcCrz0RY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:Q15654 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676869|imex:IM-22977-243 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606 intact-crc:A43BF203AC1F80C1|rigid:lqhLuQdZeyGZbvvv9o2VSccp+Tk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:P82932 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-716172|uniprotkb:Q96Q64|uniprotkb:Q9BSK8|uniprotkb:Q9BW89|uniprotkb:B2R573|ensembl:ENSP00000382250 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:rt06_human(display_long)|uniprotkb:MRPS6(gene name)|psi-mi:MRPS6(display_short)|uniprotkb:C21orf101(gene name synonym)|uniprotkb:RPMS6(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein bS6m(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676864|imex:IM-22977-242 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_115865.1|ensembl:ENSG00000243927(gene)|ensembl:ENST00000399312(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR000529(Ribosomal protein S6)|interpro:IPR014717(Translation elongation factor EF1B/ribosomal protein S6)|interpro:IPR035980|mint:P82932|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZSA|rcsb pdb:6ZS9|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:mMPTr45GZxT1pj2RBZvvG6TrQmo9606 intact-crc:1F56880DE0EC8957|rigid:i3xXdNaXW0JVBwMoWJJckFbZ+IQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:Q5W5X9 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-6447954|ensembl:ENSP00000377690|ensembl:ENSP00000377692|ensembl:ENSP00000452923|uniprotkb:A8K6M5|uniprotkb:Q96BC9|uniprotkb:Q53HK0|uniprotkb:Q9H9S7|uniprotkb:Q9H8W9 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:ttc23_human(display_long)|uniprotkb:Cervical cancer proto-oncogene 8 protein(gene name synonym)|uniprotkb:HCC8(orf name)|uniprotkb:TTC23(gene name)|psi-mi:TTC23(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676859|imex:IM-22977-241 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:XP_016878001.1|refseq:XP_016878002.1|refseq:XP_016878003.1|refseq:XP_016878004.1|refseq:XP_016878005.1|refseq:XP_016878006.1|refseq:XP_016878007.1|ensembl:ENSG00000103852(gene)|ensembl:ENST00000394132(transcript)|ensembl:ENST00000394135(transcript)|ensembl:ENST00000558663(transcript)|go:"GO:0005929"(cilium)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR042621|refseq:NP_001275544.1|refseq:NP_001275545.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:9nX5a+iLJlIBNrWGL+LaB6HNUE09606 intact-crc:1B8692ADB6D7DC7B|rigid:0346ff2aCpwFg7R+95beF7F8+U8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:Q9HAQ2 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-8472129|intact:MINT-8417679|uniprotkb:Q9H8A4|uniprotkb:Q86Z28|ensembl:ENSP00000265529|ensembl:ENSP00000391100|ensembl:ENSP00000507186 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:kif9_human(display_long)|uniprotkb:KIF9(gene name)|psi-mi:KIF9(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676854|imex:IM-22977-240 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:XP_011532306.1|refseq:NP_071737.1|refseq:NP_001128350.1|refseq:NP_878905.2|refseq:XP_016862518.1|ensembl:ENSG00000088727(gene)|ensembl:ENST00000265529(transcript)|ensembl:ENST00000452770(transcript)|ensembl:ENST00000684063(transcript)|go:"GO:0002102"(podosome)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0031982"(vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0071801"(regulation of podosome assembly)|go:"GO:1903008"(organelle disassembly)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|mint:Q9HAQ2|rcsb pdb:3NWN|reactome:R-HSA-6811434|reactome:R-HSA-983189 psi-mi:"MI:0471"(mint) - comment:mint|comment:homomint figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:53+NnzzIaB0e+FlgTdFXGvetKtg9606 intact-crc:475A7947E5E8D290|rigid:9zzXM0MEiWtUP/sfL4+DvggkpjE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:Q9GZT8 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-740897|uniprotkb:Q9H2D2|uniprotkb:Q9HC18|uniprotkb:Q6X735|uniprotkb:Q53TX4|ensembl:ENSP00000386394|ensembl:ENSP00000387315|ensembl:ENSP00000498853 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:nif3l_human(display_long)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein(gene name synonym)|uniprotkb:MDS015(orf name)|uniprotkb:My018(orf name)|uniprotkb:NIF3L1(gene name)|psi-mi:NIF3L1(display_short)|uniprotkb:ALS2CR1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676849|imex:IM-22977-239 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_001129511.1|refseq:NP_001135827.1|refseq:NP_068596.2|refseq:XP_011509887.1|refseq:XP_011509884.1|refseq:XP_011509885.1|refseq:XP_011509886.1|refseq:NP_001135828.1|refseq:XP_005246799.1|refseq:XP_016860119.1|ensembl:ENSG00000196290(gene)|ensembl:ENST00000409020(transcript)|ensembl:ENST00000409357(transcript)|ensembl:ENST00000651500(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1903507"(negative regulation of nucleic acid-templated transcription)|interpro:IPR002678(NGG1p interacting factor 3, NIF3)|interpro:IPR017222(Uncharacterised conserved protein UCP037490, NIF3, eukaryota)|interpro:IPR036069|mint:Q9GZT8 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:Vvyb7CJpcwGtGAVKT2Zoqycr2yQ9606 intact-crc:F3D00606106C78B1|rigid:x17gWkhywLJG4lBfe0ESvGuhKis false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q33E94 uniprotkb:P14079 intact:EBI-9675925|uniprotkb:Q33DW7|uniprotkb:Q8SNA1|uniprotkb:Q33E95|uniprotkb:Q8NDF9|uniprotkb:B2RDW4|uniprotkb:Q96S80|uniprotkb:Q6YM53|uniprotkb:A8K5Y0|uniprotkb:Q8NC78|uniprotkb:Q33DW6|uniprotkb:Q9BXI0|uniprotkb:Q8MHQ1|ensembl:ENSP00000376585 intact:EBI-9675698|uniprotkb:O56231 psi-mi:rfx4_human(display_long)|uniprotkb:RFX4(gene name)|psi-mi:RFX4(display_short)|uniprotkb:Regulatory factor X 4(gene name synonym)|uniprotkb:Testis development protein NYD-SP10(gene name synonym) psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676844|imex:IM-22977-238 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001193620.1|refseq:NP_115880.2|refseq:NP_998759.1|ensembl:ENSG00000111783(gene)|ensembl:ENST00000392842(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0021537"(telencephalon development)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060271"(cilium assembly)|go:"GO:0070613"(regulation of protein processing)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003150(DNA-binding RFX)|interpro:IPR036388|interpro:IPR036390|interpro:IPR039779 interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:O/qU4dSVZOwdQyCzqRqgouHNd6s9606 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 intact-crc:E5FCEDBB9794AA5C|rigid:03tv8gQUXP/mF/ijK4sarQnvvao false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:Q53HC0 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-719994|uniprotkb:Q9H697|uniprotkb:B3KNQ0|ensembl:ENSP00000238156|ensembl:ENSP00000488830 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:ccd92_human(display_long)|uniprotkb:Limkain beta-2(gene name synonym)|uniprotkb:CCDC92(gene name)|psi-mi:CCDC92(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676899|imex:IM-22977-249 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_079416.1|ensembl:ENSG00000119242(gene)|ensembl:ENSG00000275035(gene)|ensembl:ENST00000238156(transcript)|ensembl:ENST00000632401(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR033224|interpro:IPR039496|interpro:IPR040370|mint:Q53HC0|refseq:NP_001291886.1|refseq:NP_001291887.1|refseq:NP_001291888.1|refseq:NP_001291889.1|refseq:NP_001291890.1|refseq:XP_005253681.1|refseq:XP_016875473.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:Iu/FzTqEpzn8N5WUTt1OwoKWxyc9606 intact-crc:4E7BCE8C9FE350CD|rigid:6KI5X6DXx27+SUDj5xhWPc5/sKo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:Q6ZVK8 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-740486|intact:EBI-954151|ensembl:ENSP00000480722|uniprotkb:Q9H687|uniprotkb:Q8IZ75 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:nud18_human(display_long)|uniprotkb:NUDT18(gene name)|psi-mi:NUDT18(display_short)|uniprotkb:2-hydroxy-dADP phosphatase(gene name synonym)|uniprotkb:7,8-dihydro-8-oxoguanine phosphatase(gene name synonym)|uniprotkb:MTH3(gene name synonym)|uniprotkb:MutT homolog 3(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 18(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676894|imex:IM-22977-248 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_079091.3|ensembl:ENST00000611621(transcript)|ensembl:ENSG00000275074(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0044715"(8-oxo-dGDP phosphatase activity)|go:"GO:0044716"(8-oxo-GDP phosphatase activity)|go:"GO:0044717"(8-hydroxy-dADP phosphatase activity)|go:"GO:0046057"(dADP catabolic process)|go:"GO:0046067"(dGDP catabolic process)|go:"GO:0046712"(GDP catabolic process)|go:"GO:0055086"(nucleobase-containing small molecule metabolic process)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR020476|interpro:IPR042970|rcsb pdb:3GG6|rcsb pdb:4HVY|reactome:R-HSA-2393930 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:IBrXB2HhvhcyxMTQ0Xs5hGiimzA9606 intact-crc:10862C176756D621|rigid:iqmd6OEDYiB8xhFLBLx7NvQuFwc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8N883 uniprotkb:P14079 intact:EBI-9675993|uniprotkb:Q9BSN8|uniprotkb:Q8TCF4|uniprotkb:Q494T8|ensembl:ENSP00000270649 intact:EBI-9675698|uniprotkb:O56231 psi-mi:zn614_human(display_long)|uniprotkb:ZNF614(gene name)|psi-mi:ZNF614(display_short) psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676889|imex:IM-22977-247 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079316.2|ensembl:ENSG00000142556(gene)|ensembl:ENST00000270649(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436 interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:DTfWPcCHy/ZIwvALRCnGC6SMX749606 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 intact-crc:CA13EB088C0D7F5C|rigid:Hr2UBhwM50pqrX2T12B5CslJQTc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:Q6ZVK8 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-740486|intact:EBI-954151|ensembl:ENSP00000480722|uniprotkb:Q9H687|uniprotkb:Q8IZ75 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:nud18_human(display_long)|uniprotkb:NUDT18(gene name)|psi-mi:NUDT18(display_short)|uniprotkb:2-hydroxy-dADP phosphatase(gene name synonym)|uniprotkb:7,8-dihydro-8-oxoguanine phosphatase(gene name synonym)|uniprotkb:MTH3(gene name synonym)|uniprotkb:MutT homolog 3(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 18(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676884|imex:IM-22977-246 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_079091.3|ensembl:ENST00000611621(transcript)|ensembl:ENSG00000275074(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0044715"(8-oxo-dGDP phosphatase activity)|go:"GO:0044716"(8-oxo-GDP phosphatase activity)|go:"GO:0044717"(8-hydroxy-dADP phosphatase activity)|go:"GO:0046057"(dADP catabolic process)|go:"GO:0046067"(dGDP catabolic process)|go:"GO:0046712"(GDP catabolic process)|go:"GO:0055086"(nucleobase-containing small molecule metabolic process)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR020476|interpro:IPR042970|rcsb pdb:3GG6|rcsb pdb:4HVY|reactome:R-HSA-2393930 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:IBrXB2HhvhcyxMTQ0Xs5hGiimzA9606 intact-crc:688A75FE70BE276F|rigid:iqmd6OEDYiB8xhFLBLx7NvQuFwc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:Q9BY27 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-742953|ensembl:ENSP00000248879|uniprotkb:Q9BW33|uniprotkb:A8K1N7|uniprotkb:D3DX29|uniprotkb:B3KMC0 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:dgc6l_human(display_long)|uniprotkb:DiGeorge syndrome critical region 6-like protein(gene name synonym)|uniprotkb:DGCR6L(gene name)|psi-mi:DGCR6L(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676929|imex:IM-22977-255 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) go:"GO:0005634"(nucleus)|interpro:IPR010849(DiGeorge syndrome critical 6)|ensembl:ENSG00000128185(gene)|ensembl:ENST00000248879(transcript)|refseq:NP_150282.2 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:kgKOLihCtc75qwW051IZsGLspI09606 intact-crc:B6F13EA61DEEA839|rigid:7ojyAekopTtJ6YR6b7+YYowkRyw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:Q8IUF8 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-751580|uniprotkb:Q6AHW4|uniprotkb:Q6SKS0|uniprotkb:Q8IU69|uniprotkb:Q8IUF6|uniprotkb:Q8IUF7|uniprotkb:Q96KB0|uniprotkb:Q96C17|uniprotkb:D3DN35|ensembl:ENSP00000328251|ensembl:ENSP00000377748 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:riox2_human(display_long)|uniprotkb:RIOX2(gene name)|psi-mi:RIOX2(display_short)|uniprotkb:60S ribosomal protein L27a histidine hydroxylase(gene name synonym)|uniprotkb:Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA(gene name synonym)|uniprotkb:Histone lysine demethylase MINA(gene name synonym)|uniprotkb:MDIG(gene name synonym)|uniprotkb:MINA(gene name synonym)|uniprotkb:MINA53(gene name synonym)|uniprotkb:MYC-induced nuclear antigen(gene name synonym)|uniprotkb:Mineral dust-induced gene protein(gene name synonym)|uniprotkb:NO52(gene name synonym)|uniprotkb:Nucleolar protein 52(gene name synonym)|uniprotkb:Ribosomal oxygenase MINA(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676924|imex:IM-22977-254 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_001035998.1|refseq:NP_116167.3|refseq:NP_694822.2|refseq:NP_001248758.1|refseq:XP_005247895.1|dip:DIP-28141N|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR039994|mint:Q8IUF8|rcsb pdb:2XDV|rcsb pdb:4BU2|rcsb pdb:4BXF|reactome:R-HSA-3214842|ensembl:ENSG00000170854(gene)|ensembl:ENST00000333396(transcript)|ensembl:ENST00000394198(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity) psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:tdjUsv9EuHn+AADASjfGu9U15Xc9606 intact-crc:251FC499739DA668|rigid:V1d91icJHWkGK6GKOkVnGzvpqh4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:Q5H9K5 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-2818620|uniprotkb:Q8NDS3|uniprotkb:Q96JN6|ensembl:ENSP00000361868|ensembl:ENSP00000437529 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:zmat1_human(display_long)|uniprotkb:ZMAT1(gene name)|psi-mi:ZMAT1(display_short)|uniprotkb:KIAA1789(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676919|imex:IM-22977-253 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) ensembl:ENSG00000166432(gene)|ensembl:ENST00000372782(transcript)|ensembl:ENST00000540921(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001269329.1|refseq:NP_001269330.1|refseq:XP_006724774.1|refseq:XP_016885393.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:hN4WqKioK0ZoOheB8rdh/4RaDX89606 intact-crc:13A641A9A89297BE|rigid:TEhoU2dHhpFQB5sa90IIuNI6Eoo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:Q9C086 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-715611|ensembl:ENSP00000233331 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:in80b_human(display_long)|uniprotkb:PAP-1-associated protein 1(gene name synonym)|uniprotkb:High mobility group AT-hook 1-like 4(gene name synonym)|uniprotkb:INO80B(gene name)|psi-mi:INO80B(display_short)|uniprotkb:HMGA1L4(gene name synonym)|uniprotkb:PAPA1(gene name synonym)|uniprotkb:ZNHIT4(gene name synonym)|uniprotkb:Zinc finger HIT domain-containing protein 4(gene name synonym)|uniprotkb:IES2 homolog(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676914|imex:IM-22977-252 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_112578.2|interpro:IPR029523|mint:Q9C086|rcsb pdb:6HTS|reactome:R-HSA-5689603|reactome:R-HSA-5696394|interpro:IPR007529(Zinc finger, HIT-type)|ensembl:ENSG00000115274(gene)|ensembl:ENST00000233331(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0031011"(Ino80 complex)|go:"GO:0043044"|go:"GO:0046872"(metal ion binding)|interpro:IPR006880(PAPA-1-like conserved region) psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:4nwc9Jv4wjrMHJTe7kMJt1Z0nks9606 intact-crc:B84DAB49C65A72EC|rigid:+93QJl5Q0Wu4Y8SsZ3KfP7gVGn4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:Q96MT8 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-741977|uniprotkb:Q96CR0|uniprotkb:Q9H8F5|uniprotkb:Q9H8N0|uniprotkb:D3DND8|uniprotkb:D3DND9|uniprotkb:D3DNE0|ensembl:ENSP00000426129|ensembl:ENSP00000475903|ensembl:ENSP00000502085|ensembl:ENSP00000506896 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:cep63_human(display_long)|uniprotkb:CEP63(gene name)|psi-mi:CEP63(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676909|imex:IM-22977-251 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) go:"GO:0000922"(spindle pole)|go:"GO:0005829"(cytosol)|refseq:NP_001035842.1|refseq:NP_001035843.1|refseq:NP_001035859.1|refseq:NP_079456.2|ensembl:ENSG00000182923(gene)|ensembl:ENST00000513612(transcript)|ensembl:ENST00000606977(transcript)|ensembl:ENST00000675561(transcript)|ensembl:ENST00000683596(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005814"(centriole)|go:"GO:0005813"(centrosome)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|interpro:IPR029608|interpro:IPR031470|mint:Q96MT8|rcsb pdb:6CSU|rcsb pdb:6CSV|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|go:"GO:0007099"(centriole replication)|refseq:XP_011511496.1|refseq:XP_005247854.1|refseq:XP_006713823.1|refseq:XP_016862743.1|refseq:XP_016862744.1|refseq:XP_016862745.1|refseq:XP_016862751.1|refseq:XP_016862752.1|refseq:XP_016862753.1|refseq:XP_016862755.1|refseq:XP_016862756.1|dip:DIP-36374N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:/WPfint+sTGNCYCH9XG5rPYSOm09606 intact-crc:24EED4B9A32EF27B|rigid:m33nyxKJYvhOb1y+xLbuKM7yhcY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:Q96MT8 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-741977|uniprotkb:Q96CR0|uniprotkb:Q9H8F5|uniprotkb:Q9H8N0|uniprotkb:D3DND8|uniprotkb:D3DND9|uniprotkb:D3DNE0|ensembl:ENSP00000426129|ensembl:ENSP00000475903|ensembl:ENSP00000502085|ensembl:ENSP00000506896 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:cep63_human(display_long)|uniprotkb:CEP63(gene name)|psi-mi:CEP63(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676904|imex:IM-22977-250 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) go:"GO:0000922"(spindle pole)|go:"GO:0005829"(cytosol)|refseq:NP_001035842.1|refseq:NP_001035843.1|refseq:NP_001035859.1|refseq:NP_079456.2|ensembl:ENSG00000182923(gene)|ensembl:ENST00000513612(transcript)|ensembl:ENST00000606977(transcript)|ensembl:ENST00000675561(transcript)|ensembl:ENST00000683596(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005814"(centriole)|go:"GO:0005813"(centrosome)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|interpro:IPR029608|interpro:IPR031470|mint:Q96MT8|rcsb pdb:6CSU|rcsb pdb:6CSV|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|go:"GO:0007099"(centriole replication)|refseq:XP_011511496.1|refseq:XP_005247854.1|refseq:XP_006713823.1|refseq:XP_016862743.1|refseq:XP_016862744.1|refseq:XP_016862745.1|refseq:XP_016862751.1|refseq:XP_016862752.1|refseq:XP_016862753.1|refseq:XP_016862755.1|refseq:XP_016862756.1|dip:DIP-36374N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:/WPfint+sTGNCYCH9XG5rPYSOm09606 intact-crc:5CE28D50B4C60335|rigid:m33nyxKJYvhOb1y+xLbuKM7yhcY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:Q92546 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-2823702|uniprotkb:Q5TCV5|ensembl:ENSP00000367318 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:rgp1_human(display_long)|uniprotkb:RGP1(gene name)|psi-mi:RGP1(display_short)|uniprotkb:Retrograde Golgi transport protein RGP1 homolog(gene name synonym)|uniprotkb:KIAA0258(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676964|imex:IM-22977-262 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_001073965.2|ensembl:ENSG00000107185(gene)|ensembl:ENST00000378078(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034066"(Ric1-Rgp1 guanyl-nucleotide exchange factor complex)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:1903363"(negative regulation of cellular protein catabolic process)|interpro:IPR014848(Rgp1)|reactome:R-HSA-6811438|reactome:R-HSA-6811440|reactome:R-HSA-8876198 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:1clc9Psb0xKDstfEkTk/dxivDfM9606 intact-crc:B69E74F328AAAE48|rigid:iYxKJA+9erFJAczH6Mw/xQcZmE4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:Q7L2R6 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-9676069|uniprotkb:A8MYG0|uniprotkb:B9EIL1|uniprotkb:Q9BV49|uniprotkb:B7ZAI5|uniprotkb:B4DF18|ensembl:ENSP00000379689 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:zn765_human(display_long)|uniprotkb:ZNF765(gene name)|psi-mi:ZNF765(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676959|imex:IM-22977-261 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_001035275.1|ensembl:ENSG00000196417(gene)|ensembl:ENST00000396408(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:MS5zXNA3eHIBbkf6TPiX+bwOw8Q9606 intact-crc:0D032BFA80EB9E2E|rigid:to1aqlkw9mugzsQ2vm6AyUUZZzY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:O14964 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676954|imex:IM-22977-260 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606 intact-crc:CECD86EB8F8A2A57|rigid:qUv1su1OTbVGQ03lScj/r5VT2Fw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:O14964 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676949|imex:IM-22977-259 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606 intact-crc:B6C1DF029862DB19|rigid:qUv1su1OTbVGQ03lScj/r5VT2Fw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:Q969F0 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-743099|ensembl:ENSP00000359375 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:fate1_human(display_long)|uniprotkb:Tumor antigen BJ-HCC-2(gene name synonym)|uniprotkb:Cancer/testis antigen 43(gene name synonym)|uniprotkb:FATE1(gene name)|psi-mi:FATE1(display_short)|uniprotkb:FATE(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676944|imex:IM-22977-258 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_149076.1|ensembl:ENSG00000147378(gene)|ensembl:ENST00000370350(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|interpro:IPR039153|interpro:IPR039433|mint:Q969F0 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:Nm1N6lO92MHr5rIKC007oouF5RE9606 intact-crc:82A8D2F30EB53C92|rigid:nKr2+UEHSKF/5jctkdLdn5Zb5TI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:P78560 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-520375|uniprotkb:B7Z2Q5|ensembl:ENSP00000327647|ensembl:ENSP00000439068 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:cradd_human(display_long)|uniprotkb:Caspase and RIP adapter with death domain(gene name synonym)|uniprotkb:RIP-associated protein with a death domain(gene name synonym)|uniprotkb:CRADD(gene name)|psi-mi:CRADD(display_short)|uniprotkb:RAIDD(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676939|imex:IM-22977-257 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_003796.1|refseq:NP_001307029.1|refseq:NP_001307030.1|refseq:NP_001307028.1|refseq:XP_016875633.1|ensembl:ENSG00000169372(gene)|ensembl:ENST00000332896(transcript)|ensembl:ENST00000542893(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005829"(cytosol)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0070513"(death domain binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000488(Death)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR011029(DEATH-like)|interpro:IPR037926|interpro:IPR037939|interpro:IPR042148|mint:P78560|rcsb pdb:2O71|rcsb pdb:2OF5|rcsb pdb:3CRD|reactome:R-HSA-6803207|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm) psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:koYvv+L+23G4lMEFIFmYYBNaNkk9606 intact-crc:3DFC40390E6F1A8E|rigid:0jPLmZ5kahwMuAt4JZAfGjEdWEs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14079 uniprotkb:Q9UJX2 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-396137|uniprotkb:O75433|uniprotkb:Q9BS73|uniprotkb:B4E3A2|uniprotkb:B7WP05|uniprotkb:Q53FN2|uniprotkb:A8K6E5|uniprotkb:D3DQB7|ensembl:ENSP00000378350 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:cdc23_human(display_long)|uniprotkb:CDC23(gene name)|psi-mi:CDC23(display_short)|uniprotkb:ANAPC8(gene name synonym)|uniprotkb:Anaphase-promoting complex subunit 8(gene name synonym)|uniprotkb:Cyclosome subunit 8(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676934|imex:IM-22977-256 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_004652.2|dip:DIP-32959N|ensembl:ENSG00000094880(gene)|ensembl:ENST00000394886(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007091"(metaphase/anaphase transition of mitotic cell cycle)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR007192(Cdc23)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q9UJX2|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:uTZL2UHzZHLoKnio/1LcuSzZpW09606 intact-crc:C30B69DA318EAE36|rigid:ZvYOFI3dBj0LUT2OupLzmgSVehQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03346 uniprotkb:Q719H9 intact:EBI-9676099 intact:EBI-9027502|uniprotkb:A8K1F5|ensembl:ENSP00000314831|ensembl:ENSP00000384367|ensembl:ENSP00000408405|ensembl:ENSP00000464170 psi-mi:gag_htlv2(display_long)|uniprotkb:gag(gene name)|psi-mi:gag(display_short)|uniprotkb:Pr53Gag(gene name synonym) psi-mi:kctd1_human(display_long)|uniprotkb:KCTD1(gene name)|psi-mi:KCTD1(display_short)|uniprotkb:C18orf5(gene name synonym)|uniprotkb:Potassium channel tetramerization domain-containing protein 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676989|imex:IM-22977-267 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR003139(Delta-retroviral matrix, N-terminal)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010999(Retroviral matrix, N-terminal)|rcsb pdb:1JVR|refseq:NP_041002.1|interpro:IPR036875|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016032"(viral process)|go:"GO:0019013"(viral nucleocapsid) refseq:XP_016881197.1|refseq:NP_001129677.1|refseq:NP_001136202.1|refseq:NP_001245150.1|refseq:NP_945342.1|ensembl:ENSG00000134504(gene)|ensembl:ENST00000317932(transcript)|ensembl:ENST00000408011(transcript)|ensembl:ENST00000417602(transcript)|ensembl:ENST00000579973(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR011333(BTB/POZ fold)|mint:Q719H9|rcsb pdb:5BXB|rcsb pdb:5BXD|rcsb pdb:6S4L|reactome:R-HSA-8866904 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:i0OVEZNGSX2eXoKpHd0xWBzfWA811909 rogid:mv4g8/+TuoNkCitdTYpsxJH52I09606 intact-crc:A5FF0DB369F0009E|rigid:tbFcYZQ8I+hupGNp+x7aITO7E2E false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03346 uniprotkb:Q9UBB9 intact:EBI-9676099 intact:EBI-1105213|uniprotkb:O95908|uniprotkb:Q5H8V8|uniprotkb:Q9UGV7|uniprotkb:Q9Y2Q8|ensembl:ENSP00000383892|ensembl:ENSP00000384297|ensembl:ENSP00000384421|ensembl:ENSP00000480171|ensembl:ENSP00000385861|uniprotkb:Q20WL0 psi-mi:gag_htlv2(display_long)|uniprotkb:gag(gene name)|psi-mi:gag(display_short)|uniprotkb:Pr53Gag(gene name synonym) psi-mi:tfp11_human(display_long)|uniprotkb:TFIP11(gene name)|psi-mi:TFIP11(display_short)|uniprotkb:HSPC006(orf name)|uniprotkb:STIP(gene name synonym)|uniprotkb:Septin and tuftelin-interacting protein 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676984|imex:IM-22977-266 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR003139(Delta-retroviral matrix, N-terminal)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010999(Retroviral matrix, N-terminal)|rcsb pdb:1JVR|refseq:NP_041002.1|interpro:IPR036875|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016032"(viral process)|go:"GO:0019013"(viral nucleocapsid) ensembl:ENSG00000100109(gene)|refseq:NP_001008697.1|refseq:NP_036275.1|go:"GO:0016607"(nuclear speck)|ensembl:ENST00000405938(transcript)|ensembl:ENST00000407148(transcript)|ensembl:ENST00000407431(transcript)|ensembl:ENST00000407690(transcript)|ensembl:ENST00000619735(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|interpro:IPR022159|interpro:IPR022783|interpro:IPR024933|mint:Q9UBB9|reactome:R-HSA-72163|refseq:XP_011528381.1|refseq:XP_016884224.1|refseq:NP_001333786.1|refseq:NP_001333787.1|refseq:NP_001333788.1|refseq:NP_001333790.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:i0OVEZNGSX2eXoKpHd0xWBzfWA811909 rogid:Brk0v9dAoy5ntoJVHFsvt+FFE3g9606 intact-crc:9C438BD284BFE7B3|rigid:Z1l1AXVohJDtdcE7g1WLblUFJSU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03346 uniprotkb:Q8N448 intact:EBI-9676099 intact:EBI-2340947|uniprotkb:Q6ZMH2|uniprotkb:Q5W0P0|uniprotkb:Q96SH4|ensembl:ENSP00000325929|ensembl:ENSP00000497224 psi-mi:gag_htlv2(display_long)|uniprotkb:gag(gene name)|psi-mi:gag(display_short)|uniprotkb:Pr53Gag(gene name synonym) psi-mi:lnx2_human(display_long)|uniprotkb:LNX2(gene name)|psi-mi:LNX2(display_short)|uniprotkb:PDZRN1(gene name synonym)|uniprotkb:Numb-binding protein 2(gene name synonym)|uniprotkb:PDZ domain-containing RING finger protein 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676979|imex:IM-22977-265 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR003139(Delta-retroviral matrix, N-terminal)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010999(Retroviral matrix, N-terminal)|rcsb pdb:1JVR|refseq:NP_041002.1|interpro:IPR036875|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016032"(viral process)|go:"GO:0019013"(viral nucleocapsid) refseq:NP_699202.1|refseq:XP_016875923.1|ensembl:ENSG00000139517(gene)|ensembl:ENST00000316334(transcript)|ensembl:ENST00000649248(transcript)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036034|mint:Q8N448|rcsb pdb:2VWR|rcsb pdb:5DIN|rcsb pdb:5E11|rcsb pdb:5E1Y|rcsb pdb:5E21|rcsb pdb:5E22 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:i0OVEZNGSX2eXoKpHd0xWBzfWA811909 rogid:cIS5t4XkbnIgelDlUc692nI285g9606 intact-crc:ED0A1CC1E41F4F7C|rigid:RKfWd06J0TbiNw54SvcYCPRypbA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03346 uniprotkb:Q07687 intact:EBI-9676099 intact:EBI-3908234|intact:EBI-28987231|ensembl:ENSP00000234198|uniprotkb:B4DMK4|uniprotkb:B7ZA14 psi-mi:gag_htlv2(display_long)|uniprotkb:gag(gene name)|psi-mi:gag(display_short)|uniprotkb:Pr53Gag(gene name synonym) psi-mi:dlx2_human(display_long)|uniprotkb:DLX2(gene name)|psi-mi:DLX2(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676974|imex:IM-22977-264 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR003139(Delta-retroviral matrix, N-terminal)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010999(Retroviral matrix, N-terminal)|rcsb pdb:1JVR|refseq:NP_041002.1|interpro:IPR036875|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016032"(viral process)|go:"GO:0019013"(viral nucleocapsid) refseq:NP_004396.1|ensembl:ENSP00000234198|ensembl:ENST00000466293|ensembl:ENSP00000446904|ensembl:ENSG00000115844(gene)|ensembl:ENST00000234198(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0021544"(subpallium development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021893"(cerebral cortex GABAergic interneuron fate commitment)|go:"GO:0030154"(cell differentiation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0048755"(branching morphogenesis of a nerve)|go:"GO:0051216"(cartilage development)|go:"GO:1902871"(positive regulation of amacrine cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR022135 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:i0OVEZNGSX2eXoKpHd0xWBzfWA811909 rogid:q2XVmJGOg+QrKEqqAYvC5LqS4ag9606 intact-crc:9DBB3CAEBDBDABBF|rigid:dEei1iB26OAEtxEd+jMWN88DK8I false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03383 uniprotkb:O43513 intact:EBI-9676086|uniprotkb:P03382 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 psi-mi:env_htlv2(display_long)|uniprotkb:env(gene name)|psi-mi:env(display_short)|uniprotkb:Env polyprotein(gene name synonym) psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676969|imex:IM-22977-263 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018154|refseq:NP_041006.1|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0055036"(virion membrane)|go:"GO:0019031"(viral envelope) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:iX64ZtD99Z1yVZ7DOWVSdgLJaTY11909 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 intact-crc:1F53B9A23D5890BB|rigid:dKvxa1OWsn5X9j4gdjbP/hruQ98 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03363 uniprotkb:P19012 intact:EBI-9676133 intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546 psi-mi:pol_htlv2(display_long)|uniprotkb:gag-pro-pol(gene name)|psi-mi:gag-pro-pol(display_short)|uniprotkb:Pr160Gag-Pro-Pol(gene name synonym) psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677024|imex:IM-22977-274 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001037(Integrase, C-terminal, retroviral)|interpro:IPR001584(Integrase, catalytic core)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR001995(Peptidase A2A, retrovirus, catalytic)|interpro:IPR002156(Ribonuclease H)|interpro:IPR003139(Delta-retroviral matrix, N-terminal)|interpro:IPR003308(Integrase, N-terminal zinc-binding domain)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR018061|interpro:IPR021109|rcsb pdb:1JVR|refseq:NP_041003.3|interpro:IPR036397|interpro:IPR036862|interpro:IPR036875|rcsb pdb:6QBT|rcsb pdb:6QBV|rcsb pdb:6QBW|interpro:IPR043502|interpro:IPR043128|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0003964"(RNA-directed DNA polymerase activity)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015074"(DNA integration)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0044826"(viral genome integration into host DNA)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0075713"(establishment of integrated proviral latency) refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:3FlrPwlig4Db1uLRMaZz+1EKx7Q11909 rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606 intact-crc:B255ABC6EE43F286|rigid:gm0TOhSxnVo1lYSZBmxJRMTbSQ4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03363 uniprotkb:Q9UBB9 intact:EBI-9676133 intact:EBI-1105213|uniprotkb:O95908|uniprotkb:Q5H8V8|uniprotkb:Q9UGV7|uniprotkb:Q9Y2Q8|ensembl:ENSP00000383892|ensembl:ENSP00000384297|ensembl:ENSP00000384421|ensembl:ENSP00000480171|ensembl:ENSP00000385861|uniprotkb:Q20WL0 psi-mi:pol_htlv2(display_long)|uniprotkb:gag-pro-pol(gene name)|psi-mi:gag-pro-pol(display_short)|uniprotkb:Pr160Gag-Pro-Pol(gene name synonym) psi-mi:tfp11_human(display_long)|uniprotkb:TFIP11(gene name)|psi-mi:TFIP11(display_short)|uniprotkb:HSPC006(orf name)|uniprotkb:STIP(gene name synonym)|uniprotkb:Septin and tuftelin-interacting protein 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677019|imex:IM-22977-273 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001037(Integrase, C-terminal, retroviral)|interpro:IPR001584(Integrase, catalytic core)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR001995(Peptidase A2A, retrovirus, catalytic)|interpro:IPR002156(Ribonuclease H)|interpro:IPR003139(Delta-retroviral matrix, N-terminal)|interpro:IPR003308(Integrase, N-terminal zinc-binding domain)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR018061|interpro:IPR021109|rcsb pdb:1JVR|refseq:NP_041003.3|interpro:IPR036397|interpro:IPR036862|interpro:IPR036875|rcsb pdb:6QBT|rcsb pdb:6QBV|rcsb pdb:6QBW|interpro:IPR043502|interpro:IPR043128|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0003964"(RNA-directed DNA polymerase activity)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015074"(DNA integration)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0044826"(viral genome integration into host DNA)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0075713"(establishment of integrated proviral latency) ensembl:ENSG00000100109(gene)|refseq:NP_001008697.1|refseq:NP_036275.1|go:"GO:0016607"(nuclear speck)|ensembl:ENST00000405938(transcript)|ensembl:ENST00000407148(transcript)|ensembl:ENST00000407431(transcript)|ensembl:ENST00000407690(transcript)|ensembl:ENST00000619735(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|interpro:IPR022159|interpro:IPR022783|interpro:IPR024933|mint:Q9UBB9|reactome:R-HSA-72163|refseq:XP_011528381.1|refseq:XP_016884224.1|refseq:NP_001333786.1|refseq:NP_001333787.1|refseq:NP_001333788.1|refseq:NP_001333790.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:3FlrPwlig4Db1uLRMaZz+1EKx7Q11909 rogid:Brk0v9dAoy5ntoJVHFsvt+FFE3g9606 intact-crc:9C421DC146BFE7B3|rigid:7K845N6JcSpmfSABMb0bHemXljE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03363 uniprotkb:Q6P597 intact:EBI-9676133 intact:EBI-1643885|uniprotkb:Q6GMU2|uniprotkb:Q8NAL1|uniprotkb:Q8WWJ9|uniprotkb:A0AVM3|uniprotkb:A2RUT6|ensembl:ENSP00000375810 psi-mi:pol_htlv2(display_long)|uniprotkb:gag-pro-pol(gene name)|psi-mi:gag-pro-pol(display_short)|uniprotkb:Pr160Gag-Pro-Pol(gene name synonym) psi-mi:klc3_human(display_long)|uniprotkb:KLC3(gene name)|psi-mi:KLC3(display_short)|uniprotkb:KLC2(gene name synonym)|uniprotkb:KLC2L(gene name synonym)|uniprotkb:kinesin light chain 2(gene name synonym)|uniprotkb:KLC2-like(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677014|imex:IM-22977-272 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001037(Integrase, C-terminal, retroviral)|interpro:IPR001584(Integrase, catalytic core)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR001995(Peptidase A2A, retrovirus, catalytic)|interpro:IPR002156(Ribonuclease H)|interpro:IPR003139(Delta-retroviral matrix, N-terminal)|interpro:IPR003308(Integrase, N-terminal zinc-binding domain)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR018061|interpro:IPR021109|rcsb pdb:1JVR|refseq:NP_041003.3|interpro:IPR036397|interpro:IPR036862|interpro:IPR036875|rcsb pdb:6QBT|rcsb pdb:6QBV|rcsb pdb:6QBW|interpro:IPR043502|interpro:IPR043128|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0003964"(RNA-directed DNA polymerase activity)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015074"(DNA integration)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0044826"(viral genome integration into host DNA)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0075713"(establishment of integrated proviral latency) refseq:NP_803136.2|ensembl:ENSG00000104892(gene)|ensembl:ENST00000391946(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0031514"(motile cilium)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043005"(neuron projection)|interpro:IPR002151(Kinesin light chain)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q6P597|reactome:R-HSA-2132295|reactome:R-HSA-5625970|reactome:R-HSA-6811434|reactome:R-HSA-983189 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:3FlrPwlig4Db1uLRMaZz+1EKx7Q11909 rogid:nFc6MpOU6+ge5OJRjn3XIM/q02g9606 intact-crc:2D7A2B102C649BDB|rigid:5GaLt2GgC+5sh7zp/rsgcxCBDgQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03363 uniprotkb:Q93062 intact:EBI-9676133 intact:EBI-740322|uniprotkb:Q92516|uniprotkb:Q92517|uniprotkb:Q92518|uniprotkb:Q96J26|uniprotkb:D3DSU9|ensembl:ENSP00000318102|ensembl:ENSP00000380486 psi-mi:pol_htlv2(display_long)|uniprotkb:gag-pro-pol(gene name)|psi-mi:gag-pro-pol(display_short)|uniprotkb:Pr160Gag-Pro-Pol(gene name synonym) psi-mi:rbpms_human(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677009|imex:IM-22977-271 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001037(Integrase, C-terminal, retroviral)|interpro:IPR001584(Integrase, catalytic core)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR001995(Peptidase A2A, retrovirus, catalytic)|interpro:IPR002156(Ribonuclease H)|interpro:IPR003139(Delta-retroviral matrix, N-terminal)|interpro:IPR003308(Integrase, N-terminal zinc-binding domain)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR018061|interpro:IPR021109|rcsb pdb:1JVR|refseq:NP_041003.3|interpro:IPR036397|interpro:IPR036862|interpro:IPR036875|rcsb pdb:6QBT|rcsb pdb:6QBV|rcsb pdb:6QBW|interpro:IPR043502|interpro:IPR043128|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0003964"(RNA-directed DNA polymerase activity)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015074"(DNA integration)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0044826"(viral genome integration into host DNA)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0075713"(establishment of integrated proviral latency) refseq:NP_001008710.1|refseq:NP_001008711.1|refseq:NP_001008712.1|refseq:NP_006858.1|ensembl:ENSG00000157110(gene)|ensembl:ENST00000320203(transcript)|ensembl:ENST00000397323(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008143"("poly(A) binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:Q93062|rcsb pdb:1BNY|rcsb pdb:5CYJ|rcsb pdb:5DET|refseq:XP_016868475.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:3FlrPwlig4Db1uLRMaZz+1EKx7Q11909 rogid:3PsLJDzqs+19eVFeQlN+yLielYM9606 intact-crc:9887A95CC68B5CA0|rigid:v0K+83AxnpIHlS2NiZT6s5OmyoI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03363 uniprotkb:O60504 intact:EBI-9676133 intact:EBI-741237|ensembl:ENSP00000240123|uniprotkb:Q5BJE4|uniprotkb:Q6NX54|uniprotkb:Q9UQE4|intact:EBI-1222937|uniprotkb:Q96FY4 psi-mi:pol_htlv2(display_long)|uniprotkb:gag-pro-pol(gene name)|psi-mi:gag-pro-pol(display_short)|uniprotkb:Pr160Gag-Pro-Pol(gene name synonym) psi-mi:vinex_human(display_long)|uniprotkb:SCAM1(gene name synonym)|uniprotkb:SH3-containing adapter molecule 1(gene name synonym)|uniprotkb:Sorbin and SH3 domain-containing protein 3(gene name synonym)|uniprotkb:SORBS3(gene name)|psi-mi:SORBS3(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677004|imex:IM-22977-270 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001037(Integrase, C-terminal, retroviral)|interpro:IPR001584(Integrase, catalytic core)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR001995(Peptidase A2A, retrovirus, catalytic)|interpro:IPR002156(Ribonuclease H)|interpro:IPR003139(Delta-retroviral matrix, N-terminal)|interpro:IPR003308(Integrase, N-terminal zinc-binding domain)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR018061|interpro:IPR021109|rcsb pdb:1JVR|refseq:NP_041003.3|interpro:IPR036397|interpro:IPR036862|interpro:IPR036875|rcsb pdb:6QBT|rcsb pdb:6QBV|rcsb pdb:6QBW|interpro:IPR043502|interpro:IPR043128|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0003964"(RNA-directed DNA polymerase activity)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015074"(DNA integration)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0044826"(viral genome integration into host DNA)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0075713"(establishment of integrated proviral latency) ensembl:ENSG00000120896(gene)|ensembl:ENST00000240123(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0017166"(vinculin binding)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0051495"(positive regulation of cytoskeleton organization)|go:"GO:0051496"(positive regulation of stress fiber assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR028510|interpro:IPR035607|interpro:IPR035608|interpro:IPR035609|interpro:IPR036028|mint:O60504|rcsb pdb:2CT3|rcsb pdb:2DLM|rcsb pdb:2NWM|rcsb pdb:2YUP|reactome:R-HSA-445355|refseq:NP_001018003.1|refseq:NP_005766.3|refseq:XP_005273428.1|refseq:XP_016868433.1|refseq:XP_016868434.1|refseq:XP_016868435.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:3FlrPwlig4Db1uLRMaZz+1EKx7Q11909 rogid:Mq3VXduU/1gqfUwliO9sBBOb/Vc9606 intact-crc:75B7BF4DCE0A469A|rigid:doB3pKJ/BZrFvmhHJRI+e9eC1cI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03346 uniprotkb:Q12933 intact:EBI-9676099 intact:EBI-355744|uniprotkb:Q96NT2|uniprotkb:A8K107|uniprotkb:B4DPJ7|uniprotkb:Q7Z337|intact:EBI-1046651|ensembl:ENSP00000247668 psi-mi:gag_htlv2(display_long)|uniprotkb:gag(gene name)|psi-mi:gag(display_short)|uniprotkb:Pr53Gag(gene name synonym) psi-mi:traf2_human(display_long)|uniprotkb:TRAF2(gene name)|psi-mi:TRAF2(display_short)|uniprotkb:TRAP3(gene name synonym)|uniprotkb:Tumor necrosis factor type 2 receptor-associated protein 3(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRAF2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676999|imex:IM-22977-269 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR003139(Delta-retroviral matrix, N-terminal)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010999(Retroviral matrix, N-terminal)|rcsb pdb:1JVR|refseq:NP_041002.1|interpro:IPR036875|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016032"(viral process)|go:"GO:0019013"(viral nucleocapsid) refseq:NP_066961.2|refseq:XP_011517279.1|refseq:XP_011517280.1|refseq:XP_011517276.1|refseq:XP_011517277.1|refseq:XP_011517278.1|ensembl:ENSG00000127191(gene)|ensembl:ENST00000247668(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002947"(tumor necrosis factor receptor superfamily complex)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0097057"(TRAF2-GSTP1 complex)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990604"(IRE1-TRAF2-ASK1 complex)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005174"(CD40 receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034351"(negative regulation of glial cell apoptotic process)|go:"GO:0034622"|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043120"(tumor necrosis factor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027133|interpro:IPR032070|interpro:IPR037305|interpro:IPR043211|mint:Q12933|rcsb pdb:1CA4|rcsb pdb:1CA9|rcsb pdb:1CZY|rcsb pdb:1CZZ|rcsb pdb:1D00|rcsb pdb:1D01|rcsb pdb:1D0A|rcsb pdb:1D0J|rcsb pdb:1F3V|rcsb pdb:1QSC|rcsb pdb:3KNV|rcsb pdb:3M06|rcsb pdb:3M0A|rcsb pdb:3M0D|reactome:R-HSA-140534|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5668541|reactome:R-HSA-5675482|reactome:R-HSA-5676594|reactome:R-HSA-5689880|reactome:R-HSA-69416|reactome:R-HSA-75893|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-9693928|refseq:XP_016870584.1|dip:DIP-6223N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:i0OVEZNGSX2eXoKpHd0xWBzfWA811909 rogid:JhaoM5kRLh3zwhXr+BsCCRNOYa09606 intact-crc:47A8760E0B48FD04|rigid:NXUiqS4ErQ+lr6AUlL0x7CdrCRs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03346 uniprotkb:Q53G59 intact:EBI-9676099 intact:EBI-740929|ensembl:ENSP00000356230|uniprotkb:A6NEN8|uniprotkb:B7Z7B8|uniprotkb:Q9HBX5 psi-mi:gag_htlv2(display_long)|uniprotkb:gag(gene name)|psi-mi:gag(display_short)|uniprotkb:Pr53Gag(gene name synonym) psi-mi:klh12_human(display_long)|uniprotkb:CUL3-interacting protein 1(gene name synonym)|uniprotkb:KLHL12(gene name)|psi-mi:KLHL12(display_short)|uniprotkb:C3IP1(gene name synonym)|uniprotkb:DKIR homolog(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9676994|imex:IM-22977-268 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR003139(Delta-retroviral matrix, N-terminal)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010999(Retroviral matrix, N-terminal)|rcsb pdb:1JVR|refseq:NP_041002.1|interpro:IPR036875|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016032"(viral process)|go:"GO:0019013"(viral nucleocapsid) go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048208"(COPII vesicle coating)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|mint:Q53G59|rcsb pdb:2VPJ|rcsb pdb:6TTK|rcsb pdb:6V7O|reactome:R-HSA-4641258|refseq:NP_067646.1|ensembl:ENSG00000117153(gene)|ensembl:ENST00000367261(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0034451"(centriolar satellite)|refseq:NP_001289980.1|refseq:NP_001290038.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:i0OVEZNGSX2eXoKpHd0xWBzfWA811909 rogid:C4I/Ys9vqNqfG61HsXRZhywP4vE9606 intact-crc:00E053AEDE9F73EC|rigid:M7/EYGZGlFdLeyS35Ijja14hzhA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q85601 uniprotkb:O43186 intact:EBI-9676175 intact:EBI-748171|uniprotkb:Q0QD45|ensembl:ENSP00000221996|ensembl:ENSP00000445565 psi-mi:rex_htlv2(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-2(gene name synonym) psi-mi:crx_human(display_long)|uniprotkb:CRX(gene name)|psi-mi:CRX(display_short)|uniprotkb:CORD2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677044|imex:IM-22977-278 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041004.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) refseq:NP_000545.1|ensembl:ENSG00000105392(gene)|ensembl:ENST00000221996(transcript)|ensembl:ENST00000539067(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050896"(response to stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:JALmnTn2BuPjeDXSyA8raxDgM0411909 rogid:v/bkO/0iLzq1Q2HtieWQQ40RF9M9606 intact-crc:6D9FF12B9702F444|rigid:6EduZwIMoH/qbIZNQQgr9Typ3uo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03363 uniprotkb:Q13064 intact:EBI-9676133 intact:EBI-2340269|ensembl:ENSP00000313881 psi-mi:pol_htlv2(display_long)|uniprotkb:gag-pro-pol(gene name)|psi-mi:gag-pro-pol(display_short)|uniprotkb:Pr160Gag-Pro-Pol(gene name synonym) psi-mi:mkrn3_human(display_long)|uniprotkb:MKRN3(gene name)|psi-mi:MKRN3(display_short)|uniprotkb:D15S9(gene name synonym)|uniprotkb:RNF63(gene name synonym)|uniprotkb:ZNF127(gene name synonym)|uniprotkb:Zinc finger protein 127(gene name synonym)|uniprotkb:RING finger protein 63(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase makorin-3(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677039|imex:IM-22977-277 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001037(Integrase, C-terminal, retroviral)|interpro:IPR001584(Integrase, catalytic core)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR001995(Peptidase A2A, retrovirus, catalytic)|interpro:IPR002156(Ribonuclease H)|interpro:IPR003139(Delta-retroviral matrix, N-terminal)|interpro:IPR003308(Integrase, N-terminal zinc-binding domain)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR018061|interpro:IPR021109|rcsb pdb:1JVR|refseq:NP_041003.3|interpro:IPR036397|interpro:IPR036862|interpro:IPR036875|rcsb pdb:6QBT|rcsb pdb:6QBV|rcsb pdb:6QBW|interpro:IPR043502|interpro:IPR043128|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0003964"(RNA-directed DNA polymerase activity)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015074"(DNA integration)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0044826"(viral genome integration into host DNA)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0075713"(establishment of integrated proviral latency) refseq:NP_005655.1|ensembl:ENSG00000179455(gene)|ensembl:ENST00000314520(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR026294|interpro:IPR031644|interpro:IPR036855|interpro:IPR041367|mint:Q13064 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:3FlrPwlig4Db1uLRMaZz+1EKx7Q11909 rogid:3sZzqtO8FoR/vVI64iFKb0iuuSc9606 intact-crc:97328D5D5428D8C7|rigid:BcA/TmkyVuQSsJZr2SYgKWYKVVE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03363 uniprotkb:Q8IYF3 intact:EBI-9676133 intact:EBI-742397|ensembl:ENSP00000340995|ensembl:ENSP00000379226|uniprotkb:Q5JQQ8|uniprotkb:Q96LZ4|uniprotkb:Q96M47|uniprotkb:Q9BXU6|uniprotkb:A8K8V6 psi-mi:pol_htlv2(display_long)|uniprotkb:gag-pro-pol(gene name)|psi-mi:gag-pro-pol(display_short)|uniprotkb:Pr160Gag-Pro-Pol(gene name synonym) psi-mi:tex11_human(display_long)|uniprotkb:TEX11(gene name)|psi-mi:TEX11(display_short)|uniprotkb:Protein ZIP4 homolog(gene name synonym)|uniprotkb:ZIP4(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677034|imex:IM-22977-276 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001037(Integrase, C-terminal, retroviral)|interpro:IPR001584(Integrase, catalytic core)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR001995(Peptidase A2A, retrovirus, catalytic)|interpro:IPR002156(Ribonuclease H)|interpro:IPR003139(Delta-retroviral matrix, N-terminal)|interpro:IPR003308(Integrase, N-terminal zinc-binding domain)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR018061|interpro:IPR021109|rcsb pdb:1JVR|refseq:NP_041003.3|interpro:IPR036397|interpro:IPR036862|interpro:IPR036875|rcsb pdb:6QBT|rcsb pdb:6QBV|rcsb pdb:6QBW|interpro:IPR043502|interpro:IPR043128|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0003964"(RNA-directed DNA polymerase activity)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015074"(DNA integration)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0044826"(viral genome integration into host DNA)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0075713"(establishment of integrated proviral latency) ensembl:ENSG00000120498(gene)|ensembl:ENST00000344304(transcript)|ensembl:ENST00000395889(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000801"(central element)|go:"GO:0005694"(chromosome)|go:"GO:0006311"(meiotic gene conversion)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008584"(male gonad development)|go:"GO:0009566"(fertilization)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0051026"(chiasma assembly)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013940(Meiosis specific protein SPO22)|interpro:IPR019734|interpro:IPR042861|refseq:NP_001003811.1|refseq:NP_112566.2|refseq:XP_011529298.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:3FlrPwlig4Db1uLRMaZz+1EKx7Q11909 rogid:xzJnHUKkYr8TqYKI9wKTTwxgB+U9606 intact-crc:3EC1CAEE7C5A68FF|rigid:82zVBJEADNgPVr6TdMBh2NaSapo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03363 uniprotkb:O14770 intact:EBI-9676133 intact:EBI-2804934|uniprotkb:Q96KI5|uniprotkb:Q9NRS3|uniprotkb:Q9NRS1|uniprotkb:Q9NRS2|uniprotkb:Q96KI4|ensembl:ENSP00000453793|uniprotkb:A6NJI5|uniprotkb:A8MWD5|uniprotkb:B3KP98|uniprotkb:B3KPQ6|uniprotkb:Q96DI2 psi-mi:pol_htlv2(display_long)|uniprotkb:gag-pro-pol(gene name)|psi-mi:gag-pro-pol(display_short)|uniprotkb:Pr160Gag-Pro-Pol(gene name synonym) psi-mi:meis2_human(display_long)|uniprotkb:MRG1(gene name synonym)|uniprotkb:Meis1-related protein 1(gene name synonym)|uniprotkb:MEIS2(gene name)|psi-mi:MEIS2(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677029|imex:IM-22977-275 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001037(Integrase, C-terminal, retroviral)|interpro:IPR001584(Integrase, catalytic core)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR001995(Peptidase A2A, retrovirus, catalytic)|interpro:IPR002156(Ribonuclease H)|interpro:IPR003139(Delta-retroviral matrix, N-terminal)|interpro:IPR003308(Integrase, N-terminal zinc-binding domain)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR018061|interpro:IPR021109|rcsb pdb:1JVR|refseq:NP_041003.3|interpro:IPR036397|interpro:IPR036862|interpro:IPR036875|rcsb pdb:6QBT|rcsb pdb:6QBV|rcsb pdb:6QBW|interpro:IPR043502|interpro:IPR043128|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0003964"(RNA-directed DNA polymerase activity)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015074"(DNA integration)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0044826"(viral genome integration into host DNA)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0075713"(establishment of integrated proviral latency) ensembl:ENSG00000134138(gene)|ensembl:ENST00000561208(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008542"(visual learning)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0031016"(pancreas development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070848"(response to growth factor)|go:"GO:0110024"(positive regulation of cardiac muscle myoblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|mint:O14770|rcsb pdb:3K2A|rcsb pdb:4XRM|rcsb pdb:5BNG|rcsb pdb:5EG0|refseq:NP_001207411.1|refseq:NP_733774.1|refseq:NP_733775.1|refseq:NP_733776.1|refseq:NP_733777.1|refseq:NP_002390.1|refseq:NP_758526.1|refseq:NP_758527.1|ensembl:ENST00000314177|ensembl:ENSP00000326296|ensembl:ENST00000338564|ensembl:ENSP00000341400|ensembl:ENST00000340545|ensembl:ENSP00000339549|ensembl:ENST00000397620|ensembl:ENSP00000380745|ensembl:ENST00000397624|ensembl:ENSP00000380749|ensembl:ENST00000424352|ensembl:ENSP00000404185|ensembl:ENST00000557796|ensembl:ENSP00000452693|ensembl:ENST00000559085|ensembl:ENSP00000453390|ensembl:ENST00000559561|ensembl:ENSP00000453497|ensembl:ENSP00000453793|refseq:XP_016877694.1|dip:DIP-61027N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:3FlrPwlig4Db1uLRMaZz+1EKx7Q11909 rogid:dzZaH/NCkNWqc4N6ZVa+i5Knqrg9606 intact-crc:75B653A91E24A2BD|rigid:BmVi4jUnfGRwXUgrTPOQZ6IQu1o false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q85601 uniprotkb:P23497 intact:EBI-9676175 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 psi-mi:rex_htlv2(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-2(gene name synonym) psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677079|imex:IM-22977-285 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041004.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:JALmnTn2BuPjeDXSyA8raxDgM0411909 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 intact-crc:490F8A3060E6EA0F|rigid:lQlD/0PRD7YCsWn6bf4Xmfh04rE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q85601 uniprotkb:Q9GZT8 intact:EBI-9676175 intact:EBI-740897|uniprotkb:Q9H2D2|uniprotkb:Q9HC18|uniprotkb:Q6X735|uniprotkb:Q53TX4|ensembl:ENSP00000386394|ensembl:ENSP00000387315|ensembl:ENSP00000498853 psi-mi:rex_htlv2(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-2(gene name synonym) psi-mi:nif3l_human(display_long)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein(gene name synonym)|uniprotkb:MDS015(orf name)|uniprotkb:My018(orf name)|uniprotkb:NIF3L1(gene name)|psi-mi:NIF3L1(display_short)|uniprotkb:ALS2CR1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677074|imex:IM-22977-284 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041004.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) refseq:NP_001129511.1|refseq:NP_001135827.1|refseq:NP_068596.2|refseq:XP_011509887.1|refseq:XP_011509884.1|refseq:XP_011509885.1|refseq:XP_011509886.1|refseq:NP_001135828.1|refseq:XP_005246799.1|refseq:XP_016860119.1|ensembl:ENSG00000196290(gene)|ensembl:ENST00000409020(transcript)|ensembl:ENST00000409357(transcript)|ensembl:ENST00000651500(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1903507"(negative regulation of nucleic acid-templated transcription)|interpro:IPR002678(NGG1p interacting factor 3, NIF3)|interpro:IPR017222(Uncharacterised conserved protein UCP037490, NIF3, eukaryota)|interpro:IPR036069|mint:Q9GZT8 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:JALmnTn2BuPjeDXSyA8raxDgM0411909 rogid:Vvyb7CJpcwGtGAVKT2Zoqycr2yQ9606 intact-crc:A863DC6F2C52B9A3|rigid:Eeg/kPnMrNcgtF3nawxkSuKXhr0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q85601 uniprotkb:Q9NZD8 intact:EBI-9676175 intact:EBI-742688|uniprotkb:B4DW44|uniprotkb:Q6ZMB6|ensembl:ENSP00000204566|ensembl:ENSP00000404111 psi-mi:rex_htlv2(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-2(gene name synonym) psi-mi:spg21_human(display_long)|uniprotkb:Spastic paraplegia 21 autosomal recessive Mast syndrome protein(gene name synonym)|uniprotkb:Acid cluster protein 33(gene name synonym)|uniprotkb:SPG21(gene name)|psi-mi:SPG21(display_short)|uniprotkb:ACP33(gene name synonym)|uniprotkb:BM-019(orf name)|uniprotkb:GL010(orf name)|uniprotkb:Spastic paraplegia 21 protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677069|imex:IM-22977-283 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041004.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) refseq:NP_001121361.1|refseq:NP_001121362.1|refseq:NP_057714.1|ensembl:ENSG00000090487(gene)|ensembl:ENST00000204566(transcript)|ensembl:ENST00000433215(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR026151|interpro:IPR029058|mint:Q9NZD8|refseq:XP_005254494.1|refseq:XP_016877786.1|refseq:XP_016877787.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:JALmnTn2BuPjeDXSyA8raxDgM0411909 rogid:MoKySBpEYFNm7Lox/HM5nnkmhkA9606 intact-crc:72BD070334F694AC|rigid:PhBBRBQZ21r8tcNqA2YD7Ybt72Y false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q85601 uniprotkb:P37198 intact:EBI-9676175 intact:EBI-347978|intact:EBI-28983799|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|uniprotkb:Q6GTM2|uniprotkb:Q503A4|uniprotkb:Q96C43|uniprotkb:Q9NSL1|uniprotkb:B3KWU5 psi-mi:rex_htlv2(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-2(gene name synonym) psi-mi:nup62_human(display_long)|uniprotkb:NUP62(gene name)|psi-mi:NUP62(display_short)|uniprotkb:62 kDa nucleoporin(gene name synonym)|uniprotkb:Nucleoporin Nup62(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677064|imex:IM-22977-282 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041004.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) refseq:NP_714941.1|ensembl:ENSG00000213024(gene)|ensembl:ENST00000352066(transcript)|ensembl:ENST00000422090(transcript)|ensembl:ENST00000596217(transcript)|ensembl:ENST00000597029(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007569"(cell aging)|go:"GO:0008219"(cell death)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0003682"(chromatin binding)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0051028"(mRNA transport)|go:"GO:0051425"(PTB domain binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072686"(mitotic spindle)|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|go:"GO:0090543"(Flemming body)|go:"GO:0098534"(centriole assembly)|go:"GO:1903438"(positive regulation of mitotic cytokinetic process)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007758(Nucleoporin, Nsp1-like, C-terminal)|interpro:IPR026010|interpro:IPR033072|mint:P37198|rcsb pdb:2H4D|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|refseq:NP_714940.1|refseq:NP_001180286.1|refseq:NP_036478.2|refseq:NP_057637.2|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|dip:DIP-29749N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:JALmnTn2BuPjeDXSyA8raxDgM0411909 rogid:v7mvKvTtVEnLMwcpUZIcdAzge009606 intact-crc:490D311EF7EE156E|rigid:uMd7gRCfPbGpX1IxaR8rSTAOZxQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q85601 uniprotkb:Q8N448 intact:EBI-9676175 intact:EBI-2340947|uniprotkb:Q6ZMH2|uniprotkb:Q5W0P0|uniprotkb:Q96SH4|ensembl:ENSP00000325929|ensembl:ENSP00000497224 psi-mi:rex_htlv2(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-2(gene name synonym) psi-mi:lnx2_human(display_long)|uniprotkb:LNX2(gene name)|psi-mi:LNX2(display_short)|uniprotkb:PDZRN1(gene name synonym)|uniprotkb:Numb-binding protein 2(gene name synonym)|uniprotkb:PDZ domain-containing RING finger protein 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677059|imex:IM-22977-281 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041004.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) refseq:NP_699202.1|refseq:XP_016875923.1|ensembl:ENSG00000139517(gene)|ensembl:ENST00000316334(transcript)|ensembl:ENST00000649248(transcript)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036034|mint:Q8N448|rcsb pdb:2VWR|rcsb pdb:5DIN|rcsb pdb:5E11|rcsb pdb:5E1Y|rcsb pdb:5E21|rcsb pdb:5E22 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:JALmnTn2BuPjeDXSyA8raxDgM0411909 rogid:cIS5t4XkbnIgelDlUc692nI285g9606 intact-crc:CEB724E3E00A2341|rigid:AvVh3MEdbHmiEfuktF2hClh3on8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q85601 uniprotkb:Q8N448 intact:EBI-9676175 intact:EBI-2340947|uniprotkb:Q6ZMH2|uniprotkb:Q5W0P0|uniprotkb:Q96SH4|ensembl:ENSP00000325929|ensembl:ENSP00000497224 psi-mi:rex_htlv2(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-2(gene name synonym) psi-mi:lnx2_human(display_long)|uniprotkb:LNX2(gene name)|psi-mi:LNX2(display_short)|uniprotkb:PDZRN1(gene name synonym)|uniprotkb:Numb-binding protein 2(gene name synonym)|uniprotkb:PDZ domain-containing RING finger protein 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677054|imex:IM-22977-280 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041004.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) refseq:NP_699202.1|refseq:XP_016875923.1|ensembl:ENSG00000139517(gene)|ensembl:ENST00000316334(transcript)|ensembl:ENST00000649248(transcript)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036034|mint:Q8N448|rcsb pdb:2VWR|rcsb pdb:5DIN|rcsb pdb:5E11|rcsb pdb:5E1Y|rcsb pdb:5E21|rcsb pdb:5E22 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:JALmnTn2BuPjeDXSyA8raxDgM0411909 rogid:cIS5t4XkbnIgelDlUc692nI285g9606 intact-crc:B6BB7D0AF7E2D20F|rigid:AvVh3MEdbHmiEfuktF2hClh3on8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q85601 uniprotkb:Q96FJ2 intact:EBI-9676175 intact:EBI-742371|uniprotkb:B2R5B4|ensembl:ENSP00000477310 psi-mi:rex_htlv2(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-2(gene name synonym) psi-mi:dyl2_human(display_long)|uniprotkb:DYNLL2(gene name)|psi-mi:DYNLL2(display_short)|uniprotkb:Dynein light chain LC8-type 2(gene name synonym)|uniprotkb:DLC2(gene name synonym)|uniprotkb:8 kDa dynein light chain b(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677049|imex:IM-22977-279 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041004.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) go:"GO:0005813"(centrosome)|refseq:NP_542408.1|ensembl:ENSG00000264364(gene)|ensembl:ENST00000579991(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0007017"(microtubule-based process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0030286"(dynein complex)|go:"GO:0031475"(myosin V complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097542"(ciliary tip)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:Q96FJ2|rcsb pdb:2XQQ|rcsb pdb:3P8M|rcsb pdb:4D07|reactome:R-HSA-139910|reactome:R-HSA-141444|reactome:R-HSA-1632852|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-5620924|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:JALmnTn2BuPjeDXSyA8raxDgM0411909 rogid:4RFpJF40RBja5mOvt/aCv3miiDU9606 intact-crc:CC88F8D07FE4F952|rigid:0i6piXIDT5hPVHTIqdAcNyclymc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:P26196 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-351257|uniprotkb:Q5D048|ensembl:ENSP00000433704|ensembl:ENSP00000442266|ensembl:ENSP00000478754 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:ddx6_human(display_long)|uniprotkb:DDX6(gene name)|psi-mi:DDX6(display_short)|uniprotkb:HLR2(gene name synonym)|uniprotkb:RCK(gene name synonym)|uniprotkb:DEAD box protein 6(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p54(gene name synonym)|uniprotkb:Oncogene RCK(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677109|imex:IM-22977-291 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_004388.2|refseq:NP_001244120.1|ensembl:ENSG00000110367(gene)|ensembl:ENST00000526070(transcript)|ensembl:ENST00000534980(transcript)|ensembl:ENST00000620157(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000932"(P-body)|go:"GO:0001520"(outer dense fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045296"(cadherin binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0097227"(sperm annulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P26196|rcsb pdb:1VEC|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT5|rcsb pdb:5ANR|rcsb pdb:6F9S|rcsb pdb:6S8S|reactome:R-HSA-430039|refseq:XP_005271474.1|dip:DIP-29195N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:pBOpwnVU+BmxUyC/uo2ig53QRto9606 intact-crc:52B61FDA701CD4EB|rigid:Qle6X+wzTjynIXb54Njjcw6vI1k false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:Q8WW24 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-750487|ensembl:ENSP00000295201 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:tekt4_human(display_long)|uniprotkb:TEKT4(gene name)|psi-mi:TEKT4(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677104|imex:IM-22977-290 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_653306.1|ensembl:ENSG00000163060(gene)|ensembl:ENST00000295201(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0036126"(sperm flagellum)|go:"GO:0060271"(cilium assembly)|go:"GO:0060294"(cilium movement involved in cell motility)|interpro:IPR000435(Tektin) psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:uSPBMKPN9VTr6rsdxgUPpfWynIA9606 intact-crc:71077142AD0A7FAE|rigid:a6XBBxghgGxvMsBFAntpEH7LKA0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:Q8N4L8 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-1104933|ensembl:ENSP00000361392|uniprotkb:Q6RWT2 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:ccd24_human(display_long)|uniprotkb:CCDC24(gene name)|psi-mi:CCDC24(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677099|imex:IM-22977-289 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) ensembl:ENSG00000159214(gene)|ensembl:ENST00000372318(transcript)|go:"GO:0001835"(blastocyst hatching)|interpro:IPR031367|refseq:NP_689712.1|refseq:XP_016855930.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:+WHY6f4VV8Z2uvuWOUYqOSCN36o9606 intact-crc:28F210B6F3E50B4D|rigid:tzmQCoiSgdUyXUWls/F4IkdhXNM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:Q96FJ2 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-742371|uniprotkb:B2R5B4|ensembl:ENSP00000477310 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:dyl2_human(display_long)|uniprotkb:DYNLL2(gene name)|psi-mi:DYNLL2(display_short)|uniprotkb:Dynein light chain LC8-type 2(gene name synonym)|uniprotkb:DLC2(gene name synonym)|uniprotkb:8 kDa dynein light chain b(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677094|imex:IM-22977-288 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) go:"GO:0005813"(centrosome)|refseq:NP_542408.1|ensembl:ENSG00000264364(gene)|ensembl:ENST00000579991(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0007017"(microtubule-based process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0030286"(dynein complex)|go:"GO:0031475"(myosin V complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097542"(ciliary tip)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:Q96FJ2|rcsb pdb:2XQQ|rcsb pdb:3P8M|rcsb pdb:4D07|reactome:R-HSA-139910|reactome:R-HSA-141444|reactome:R-HSA-1632852|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-5620924|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:4RFpJF40RBja5mOvt/aCv3miiDU9606 intact-crc:973883CAE93E6421|rigid:gVX0bDFfeiIcpLN0X+JSBtPWPeQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:O43186 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-748171|uniprotkb:Q0QD45|ensembl:ENSP00000221996|ensembl:ENSP00000445565 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:crx_human(display_long)|uniprotkb:CRX(gene name)|psi-mi:CRX(display_short)|uniprotkb:CORD2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677089|imex:IM-22977-287 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_000545.1|ensembl:ENSG00000105392(gene)|ensembl:ENST00000221996(transcript)|ensembl:ENST00000539067(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050896"(response to stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:v/bkO/0iLzq1Q2HtieWQQ40RF9M9606 intact-crc:143F304B4B99CFEA|rigid:CbXhSStMGDnr4S1rdtD3hZH+NyI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:Q9Y2D8 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677084|imex:IM-22977-286 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606 intact-crc:F8DF5172CB4D9548|rigid:4yfIE9G9j3f1FHFEjsZvM0d9kys false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:Q6PEX3 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-3957672|ensembl:ENSP00000353742|uniprotkb:B0RZD3 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:kr261_human(display_long)|uniprotkb:KRTAP26-1(gene name)|psi-mi:KRTAP26-1(display_short)|uniprotkb:KAP26.1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677144|imex:IM-22977-298 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) ensembl:ENSG00000197683(gene)|ensembl:ENST00000360542(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|interpro:IPR007951(PMG)|reactome:R-HSA-6805567|refseq:NP_981950.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:VKgQPRg2qO2FXQx0fQ/dd/5kMws9606 intact-crc:2A6D459EB22ABB6E|rigid:si8ReoMWQMPSvGPbjGA7CYOwLyY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:P19012 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677139|imex:IM-22977-297 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606 intact-crc:B2552704A964F286|rigid:mKLJpXEWDfcaiLr6DaSSHYk4YbE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:Q9NP87 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-9675790|uniprotkb:Q86WQ9|uniprotkb:D3DVK4|uniprotkb:Q6P5X8|ensembl:ENSP00000242248 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:dpolm_human(display_long)|uniprotkb:POLM(gene name)|psi-mi:POLM(display_short)|uniprotkb:Terminal transferase(gene name synonym)|uniprotkb:polmu(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677134|imex:IM-22977-296 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_001271259.1|refseq:NP_001271260.1|refseq:NP_037416.1|rcsb pdb:6IPK|rcsb pdb:6IPL|rcsb pdb:6IPM|rcsb pdb:6IPN|rcsb pdb:6P1M|rcsb pdb:6P1N|rcsb pdb:6P1O|rcsb pdb:6P1P|rcsb pdb:6P1Q|rcsb pdb:6P1R|rcsb pdb:6P1S|rcsb pdb:6P1T|rcsb pdb:6P1U|rcsb pdb:6P1V|rcsb pdb:6P1W|rcsb pdb:6WIC|rcsb pdb:6WID|rcsb pdb:6WIE|rcsb pdb:7CO6|rcsb pdb:7CO8|rcsb pdb:7CO9|rcsb pdb:7COA|rcsb pdb:7COB|rcsb pdb:7COC|rcsb pdb:7COD|reactome:R-HSA-5693571|ensembl:ENSG00000122678(gene)|ensembl:ENST00000242248(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|interpro:IPR001357(BRCT)|interpro:IPR001726(DNA nucleotidylexotransferase)|interpro:IPR002054(DNA-directed DNA polymerase, family X)|interpro:IPR010996(DNA-directed DNA polymerase, family X, beta-like, N-terminal)|interpro:IPR018944|interpro:IPR019843|interpro:IPR022312|interpro:IPR027249|interpro:IPR027421|interpro:IPR028207|interpro:IPR029398|interpro:IPR036420|interpro:IPR037160|interpro:IPR043519|rcsb pdb:2DUN|rcsb pdb:2HTF|rcsb pdb:4LZD|rcsb pdb:4LZG|rcsb pdb:4M04|rcsb pdb:4M0A|rcsb pdb:4YCX|rcsb pdb:4YD1|rcsb pdb:4YD2|rcsb pdb:5TWP|rcsb pdb:5TWQ|rcsb pdb:5TWR|rcsb pdb:5TWS|rcsb pdb:5TXX|rcsb pdb:5TXZ|rcsb pdb:5TYB|rcsb pdb:5TYC|rcsb pdb:5TYD|rcsb pdb:5TYE|rcsb pdb:5TYF|rcsb pdb:5TYG|rcsb pdb:5TYU|rcsb pdb:5TYV|rcsb pdb:5TYW|rcsb pdb:5TYX|rcsb pdb:5TYY|rcsb pdb:5TYZ|rcsb pdb:5VZ7|rcsb pdb:5VZ8|rcsb pdb:5VZ9|rcsb pdb:5VZA|rcsb pdb:5VZB|rcsb pdb:5VZC|rcsb pdb:5VZD|rcsb pdb:5VZE|rcsb pdb:5VZF|rcsb pdb:5VZG|rcsb pdb:5VZH|rcsb pdb:5VZI|rcsb pdb:5W4F|rcsb pdb:5ZLC|rcsb pdb:6AEC|rcsb pdb:6AEH|rcsb pdb:6AK5|rcsb pdb:6AK6|rcsb pdb:6AK8|rcsb pdb:6AK9|rcsb pdb:6AKH|rcsb pdb:6IPD|rcsb pdb:6IPE|rcsb pdb:6IPF|rcsb pdb:6IPG|rcsb pdb:6IPH|rcsb pdb:6IPI|rcsb pdb:6IPJ psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:PjYb9sk0XvVaJwJ3JdGQY4IvenE9606 intact-crc:97CB5BD99DAA62AB|rigid:SDYmq+6CVOVi7/mRw1A+pYSXU6U false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:P37198 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-347978|intact:EBI-28983799|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|uniprotkb:Q6GTM2|uniprotkb:Q503A4|uniprotkb:Q96C43|uniprotkb:Q9NSL1|uniprotkb:B3KWU5 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:nup62_human(display_long)|uniprotkb:NUP62(gene name)|psi-mi:NUP62(display_short)|uniprotkb:62 kDa nucleoporin(gene name synonym)|uniprotkb:Nucleoporin Nup62(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677129|imex:IM-22977-295 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_714941.1|ensembl:ENSG00000213024(gene)|ensembl:ENST00000352066(transcript)|ensembl:ENST00000422090(transcript)|ensembl:ENST00000596217(transcript)|ensembl:ENST00000597029(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007569"(cell aging)|go:"GO:0008219"(cell death)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0003682"(chromatin binding)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0051028"(mRNA transport)|go:"GO:0051425"(PTB domain binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072686"(mitotic spindle)|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|go:"GO:0090543"(Flemming body)|go:"GO:0098534"(centriole assembly)|go:"GO:1903438"(positive regulation of mitotic cytokinetic process)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007758(Nucleoporin, Nsp1-like, C-terminal)|interpro:IPR026010|interpro:IPR033072|mint:P37198|rcsb pdb:2H4D|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|refseq:NP_714940.1|refseq:NP_001180286.1|refseq:NP_036478.2|refseq:NP_057637.2|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|dip:DIP-29749N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:v7mvKvTtVEnLMwcpUZIcdAzge009606 intact-crc:A910176CC58D1C24|rigid:0aOeFxGwa2yIy+c4oRdVecWLcp8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:Q8N448 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-2340947|uniprotkb:Q6ZMH2|uniprotkb:Q5W0P0|uniprotkb:Q96SH4|ensembl:ENSP00000325929|ensembl:ENSP00000497224 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:lnx2_human(display_long)|uniprotkb:LNX2(gene name)|psi-mi:LNX2(display_short)|uniprotkb:PDZRN1(gene name synonym)|uniprotkb:Numb-binding protein 2(gene name synonym)|uniprotkb:PDZ domain-containing RING finger protein 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677124|imex:IM-22977-294 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_699202.1|refseq:XP_016875923.1|ensembl:ENSG00000139517(gene)|ensembl:ENST00000316334(transcript)|ensembl:ENST00000649248(transcript)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036034|mint:Q8N448|rcsb pdb:2VWR|rcsb pdb:5DIN|rcsb pdb:5E11|rcsb pdb:5E1Y|rcsb pdb:5E21|rcsb pdb:5E22 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:cIS5t4XkbnIgelDlUc692nI285g9606 intact-crc:95075FF976D0BE32|rigid:Hu5/ge6BY/bCqsLnV0xjt5qq6yE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:Q8N448 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-2340947|uniprotkb:Q6ZMH2|uniprotkb:Q5W0P0|uniprotkb:Q96SH4|ensembl:ENSP00000325929|ensembl:ENSP00000497224 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:lnx2_human(display_long)|uniprotkb:LNX2(gene name)|psi-mi:LNX2(display_short)|uniprotkb:PDZRN1(gene name synonym)|uniprotkb:Numb-binding protein 2(gene name synonym)|uniprotkb:PDZ domain-containing RING finger protein 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677119|imex:IM-22977-293 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_699202.1|refseq:XP_016875923.1|ensembl:ENSG00000139517(gene)|ensembl:ENST00000316334(transcript)|ensembl:ENST00000649248(transcript)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036034|mint:Q8N448|rcsb pdb:2VWR|rcsb pdb:5DIN|rcsb pdb:5E11|rcsb pdb:5E1Y|rcsb pdb:5E21|rcsb pdb:5E22 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:cIS5t4XkbnIgelDlUc692nI285g9606 intact-crc:ED0B061061384F7C|rigid:Hu5/ge6BY/bCqsLnV0xjt5qq6yE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:Q01844 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-739737|uniprotkb:Q92635|uniprotkb:Q96FE8|uniprotkb:Q96MX4|uniprotkb:Q9BWA2|uniprotkb:Q5THL0|intact:EBI-28987207|ensembl:ENSP00000381031|intact:EBI-10985407|uniprotkb:B0QYK1|uniprotkb:Q96MN4 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:ews_human(display_long)|uniprotkb:EWSR1(gene name)|psi-mi:EWSR1(display_short)|uniprotkb:EWS(gene name synonym)|uniprotkb:EWS oncogene(gene name synonym)|uniprotkb:Ewing sarcoma breakpoint region 1 protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677114|imex:IM-22977-292 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_001156757.1|refseq:NP_005234.1|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q01844|rcsb pdb:2CPE|interpro:IPR001876(Zinc finger, RanBP2-type)|ensembl:ENSG00000182944(gene)|ensembl:ENST00000397938(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001156759.1|refseq:NP_053733.2|refseq:NP_001156758.1|ensembl:ENST00000332035|ensembl:ENSP00000331699|ensembl:ENST00000333395|ensembl:ENSP00000327456|ensembl:ENSP00000381031|ensembl:ENST00000406548|ensembl:ENSP00000385726|ensembl:ENST00000414183|ensembl:ENSP00000400142|dip:DIP-34449N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:7PxoTjcmcdUA3clzf0eW+iCFaS49606 intact-crc:5B918BA453ABC539|rigid:BYm1nho/YSR651NDf7C7dvaMZqg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:Q6ZUT1 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-3920396|ensembl:ENSP00000339076|ensembl:ENSP00000402208|uniprotkb:Q7Z357|uniprotkb:Q8N2T3|uniprotkb:Q6IN53|uniprotkb:Q5RL41 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:nkap1_human(display_long)|uniprotkb:NKAPD1(gene name)|psi-mi:NKAPD1(display_short)|uniprotkb:C11orf57(gene name synonym)|uniprotkb:NKAP domain containing protein 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677174|imex:IM-22977-304 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) ensembl:ENSG00000150776(gene)|ensembl:ENST00000280352(transcript)|ensembl:ENST00000420986(transcript)|go:"GO:0042802"(identical protein binding)|interpro:IPR043407|refseq:NP_001287946.1|refseq:NP_001287948.1|refseq:NP_001287950.1|refseq:NP_001076439.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:7Lz1Il3OjnAW5tcASdyVUZf+4y89606 intact-crc:3C94E2E3C15CA979|rigid:RHUQJj45h8uuE4w1Vwz00u4bxSE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:Q96HA8 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-741158|uniprotkb:B4DE68|uniprotkb:Q9NW95|ensembl:ENSP00000287387 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:ntaq1_human(display_long)|uniprotkb:NTAQ1(gene name)|psi-mi:NTAQ1(display_short)|uniprotkb:C8orf32(gene name synonym)|uniprotkb:Protein NH2-terminal glutamine deamidase(gene name synonym)|uniprotkb:WDYHV motif-containing protein 1(gene name synonym)|uniprotkb:WDYHV1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677169|imex:IM-22977-303 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_060494.1|refseq:NP_001269953.1|ensembl:ENSG00000156795(gene)|ensembl:ENST00000287387(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008418"(protein-N-terminal asparagine amidohydrolase activity)|interpro:IPR023128|interpro:IPR037132|interpro:IPR039733|mint:Q96HA8|rcsb pdb:3C9Q|rcsb pdb:4W79|rcsb pdb:6KGJ|go:"GO:0070773"(protein-N-terminal glutamine amidohydrolase activity) psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:RKX6ww+Z/Zw6bmOXa0r8C0mxlvc9606 intact-crc:C145FC1E777D117F|rigid:ObbRcI481yv6Iu2z6fQ6TiH4nk0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:Q9P0T4 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-745520|uniprotkb:B2RDM6|ensembl:ENSP00000270451|ensembl:ENSP00000466047|ensembl:ENSP00000466564 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:zn581_human(display_long)|uniprotkb:ZNF581(gene name)|psi-mi:ZNF581(display_short)|uniprotkb:HSPC189(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677164|imex:IM-22977-302 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_057619.1|ensembl:ENSG00000171425(gene)|ensembl:ENST00000270451(transcript)|ensembl:ENST00000587252(transcript)|ensembl:ENST00000588537(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9P0T4|go:"GO:0005634"(nucleus)|refseq:XP_006723303.1|refseq:XP_016882356.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:SpE0ZPhcfXB4PnyufoyWq4iNAs89606 intact-crc:39A1EDA5F0D14B4C|rigid:fnZX+FQcRyfrXURrdYRIxpn3/3M false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:Q66PJ3 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-2683099|uniprotkb:Q9NR05|uniprotkb:Q4F966|uniprotkb:Q9P2R9|uniprotkb:Q96BI2|uniprotkb:Q504R8|uniprotkb:A4UCR8|uniprotkb:B3V0L0|uniprotkb:B3V0L1 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:ar6p4_human(display_long)|uniprotkb:HSP-975(gene name synonym)|uniprotkb:HSVI-binding protein(gene name synonym)|uniprotkb:SR-15(gene name synonym)|uniprotkb:SRp25(gene name synonym)|uniprotkb:Splicing factor SRrp37(gene name synonym)|uniprotkb:ARL6IP4(gene name)|psi-mi:ARL6IP4(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677159|imex:IM-22977-301 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) interpro:IPR019532|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|refseq:NP_001002251.2|refseq:NP_001002252.2|refseq:NP_001265307.1|refseq:NP_001265308.1|refseq:NP_001265309.1|refseq:NP_061164.3|refseq:NP_057722.3|mint:Q66PJ3 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:ZNWWhsvMwbPRZb3BlP50N3hc4Ls9606 intact-crc:B6BC6C4250B2A7A8|rigid:1mbGn8VQ0dzcakz03l44aI4mUKA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:Q9NZD8 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-742688|uniprotkb:B4DW44|uniprotkb:Q6ZMB6|ensembl:ENSP00000204566|ensembl:ENSP00000404111 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:spg21_human(display_long)|uniprotkb:Spastic paraplegia 21 autosomal recessive Mast syndrome protein(gene name synonym)|uniprotkb:Acid cluster protein 33(gene name synonym)|uniprotkb:SPG21(gene name)|psi-mi:SPG21(display_short)|uniprotkb:ACP33(gene name synonym)|uniprotkb:BM-019(orf name)|uniprotkb:GL010(orf name)|uniprotkb:Spastic paraplegia 21 protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677154|imex:IM-22977-300 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_001121361.1|refseq:NP_001121362.1|refseq:NP_057714.1|ensembl:ENSG00000090487(gene)|ensembl:ENST00000204566(transcript)|ensembl:ENST00000433215(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR026151|interpro:IPR029058|mint:Q9NZD8|refseq:XP_005254494.1|refseq:XP_016877786.1|refseq:XP_016877787.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:MoKySBpEYFNm7Lox/HM5nnkmhkA9606 intact-crc:290D7C19A22C09DF|rigid:2R/jnnVOInc6+RMFMKYwJOOakKc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:Q9UK41 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-727424|uniprotkb:Q86VK0|ensembl:ENSP00000292510|ensembl:ENSP00000434064|ensembl:ENSP00000496519|ensembl:ENSP00000496693 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:vps28_human(display_long)|uniprotkb:VPS28(gene name)|psi-mi:VPS28(display_short)|uniprotkb:ESCRT-I complex subunit VPS28(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677149|imex:IM-22977-299 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_057292.1|refseq:NP_898880.1|ensembl:ENSG00000160948(gene)|ensembl:ENSG00000285339(gene)|ensembl:ENST00000292510(transcript)|ensembl:ENST00000526054(transcript)|ensembl:ENST00000642867(transcript)|ensembl:ENST00000643186(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR007143(Vacuolar protein sorting-associated, VPS28)|interpro:IPR017898|interpro:IPR017899|interpro:IPR037202|interpro:IPR037206|interpro:IPR038358|mint:Q9UK41|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:GUcc7bRf1LaLklAYVLEHRSihPjA9606 intact-crc:91E55D83C8402C40|rigid:asB4TaUf88TiPLK6fnIODUbmeUo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:Q05516 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-711925|ensembl:ENSP00000338157|ensembl:ENSP00000376721|ensembl:ENSP00000506794|ensembl:ENSP00000506894|ensembl:ENSP00000506924|ensembl:ENSP00000506953|ensembl:ENSP00000507788|ensembl:ENSP00000508351|uniprotkb:Q8TAL4 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:zbt16_human(display_long)|uniprotkb:Zinc finger protein PLZF(gene name synonym)|uniprotkb:Promyelocytic leukemia zinc finger protein(gene name synonym)|uniprotkb:Zinc finger protein 145(gene name synonym)|uniprotkb:ZBTB16(gene name)|psi-mi:ZBTB16(display_short)|uniprotkb:PLZF(gene name synonym)|uniprotkb:ZNF145(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677209|imex:IM-22977-311 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) ensembl:ENSG00000109906(gene)|ensembl:ENST00000335953(transcript)|ensembl:ENST00000392996(transcript)|ensembl:ENST00000682278(transcript)|ensembl:ENST00000682697(transcript)|ensembl:ENST00000682971(transcript)|ensembl:ENST00000683318(transcript)|ensembl:ENST00000683554(transcript)|ensembl:ENST00000684295(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001823"(mesonephros development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043931"(ossification involved in bone maturation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048133"(male germ-line stem cell asymmetric division)|go:"GO:0051138"(positive regulation of NK T cell differentiation)|go:"GO:0051216"(cartilage development)|go:"GO:0061036"(positive regulation of cartilage development)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q05516|rcsb pdb:1BUO|rcsb pdb:1CS3|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_001018011.1|refseq:NP_005997.2|refseq:XP_016873746.1|refseq:XP_016873747.1|refseq:XP_016873748.1|dip:DIP-2654N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:wJmkU9GC3S18VXyYd8asd+hN+yU9606 intact-crc:2D73F4D4F5D28377|rigid:FQTttVzu5bsZTQmYQ/nlgfEx6r0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:P23497 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677204|imex:IM-22977-310 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 intact-crc:4A1A79E9C70C6BC4|rigid:ZMlo7twhUJAFXioQwRaEUmDdd4Y false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:P35711 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-3505701|uniprotkb:Q86UK8|uniprotkb:Q8J017|uniprotkb:Q8J018|uniprotkb:Q8J019|uniprotkb:Q8J020|uniprotkb:Q8N1D9|uniprotkb:Q8N7E0|uniprotkb:Q8TEA4|uniprotkb:B7Z8V0|uniprotkb:F5H5B0|ensembl:ENSP00000398273 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:sox5_human(display_long)|uniprotkb:SOX5(gene name)|psi-mi:SOX5(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677199|imex:IM-22977-309 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_008871.3|refseq:NP_694534.1|refseq:NP_821078.1|refseq:NP_001248343.1|refseq:NP_001248344.1|ensembl:ENSG00000134532(gene)|ensembl:ENST00000451604(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001502"(cartilage condensation)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0045165"(cell fate commitment)|go:"GO:0051216"(cartilage development)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0061036"(positive regulation of cartilage development)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:2000741"(positive regulation of mesenchymal stem cell differentiation)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|mint:P35711|refseq:NP_001317714.1|refseq:XP_016875385.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:YVl5zcnqafFgRvQt8B79kMtbz+g9606 intact-crc:050737EB9E283B68|rigid:DQz53+P9sHPbU/vTPfwDIijl15I false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:P14672 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-367146|uniprotkb:Q14CX2|uniprotkb:Q05BQ3|ensembl:ENSP00000320935|ensembl:ENSP00000499804 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:glut4_human(display_long)|uniprotkb:SLC2A4(gene name)|psi-mi:SLC2A4(display_short)|uniprotkb:GLUT4(gene name synonym)|uniprotkb:Glucose transporter type 4, insulin-responsive(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677194|imex:IM-22977-308 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_001033.1|go:"GO:0055056"(D-glucose transmembrane transporter activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0098694"(regulation of synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0098793"(presynapse)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR002441("Glucose transporter, type 4 (GLUT4)")|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|reactome:R-HSA-1445148|reactome:R-HSA-189200|reactome:R-HSA-381340|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0012505"(endomembrane system)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031550"(positive regulation of brain-derived neurotrophic factor receptor signaling pathway)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0044381"(glucose import in response to insulin stimulus)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0046323"(glucose import)|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSG00000181856(gene)|ensembl:ENSG00000288174(gene)|ensembl:ENST00000317370(transcript)|ensembl:ENST00000673224(transcript)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005771"(multivesicular body)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0007611"(learning or memory)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010021"(amylopectin biosynthetic process) psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:P9bY7eO9/4e2pVIARFLZ3qmuwHA9606 intact-crc:8E43BF0F7700330B|rigid:RIQv16sIWDk5eo5ywFfali/h/4E false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:P82932 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-716172|uniprotkb:Q96Q64|uniprotkb:Q9BSK8|uniprotkb:Q9BW89|uniprotkb:B2R573|ensembl:ENSP00000382250 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:rt06_human(display_long)|uniprotkb:MRPS6(gene name)|psi-mi:MRPS6(display_short)|uniprotkb:C21orf101(gene name synonym)|uniprotkb:RPMS6(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein bS6m(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677189|imex:IM-22977-307 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_115865.1|ensembl:ENSG00000243927(gene)|ensembl:ENST00000399312(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR000529(Ribosomal protein S6)|interpro:IPR014717(Translation elongation factor EF1B/ribosomal protein S6)|interpro:IPR035980|mint:P82932|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZSA|rcsb pdb:6ZS9|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:mMPTr45GZxT1pj2RBZvvG6TrQmo9606 intact-crc:1F55297E4A08D536|rigid:hCeLrXkOSuops84LJobStx/OcXA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:Q9GZT8 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-740897|uniprotkb:Q9H2D2|uniprotkb:Q9HC18|uniprotkb:Q6X735|uniprotkb:Q53TX4|ensembl:ENSP00000386394|ensembl:ENSP00000387315|ensembl:ENSP00000498853 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:nif3l_human(display_long)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein(gene name synonym)|uniprotkb:MDS015(orf name)|uniprotkb:My018(orf name)|uniprotkb:NIF3L1(gene name)|psi-mi:NIF3L1(display_short)|uniprotkb:ALS2CR1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677184|imex:IM-22977-306 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_001129511.1|refseq:NP_001135827.1|refseq:NP_068596.2|refseq:XP_011509887.1|refseq:XP_011509884.1|refseq:XP_011509885.1|refseq:XP_011509886.1|refseq:NP_001135828.1|refseq:XP_005246799.1|refseq:XP_016860119.1|ensembl:ENSG00000196290(gene)|ensembl:ENST00000409020(transcript)|ensembl:ENST00000409357(transcript)|ensembl:ENST00000651500(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1903507"(negative regulation of nucleic acid-templated transcription)|interpro:IPR002678(NGG1p interacting factor 3, NIF3)|interpro:IPR017222(Uncharacterised conserved protein UCP037490, NIF3, eukaryota)|interpro:IPR036069|mint:Q9GZT8 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:Vvyb7CJpcwGtGAVKT2Zoqycr2yQ9606 intact-crc:F3D3A775BA8824D0|rigid:ZM2PXr7lLwa1wyfEyh9xpDXOSjY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:A8K1J0 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-9675917 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:a8k1j0_human(display_long) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677179|imex:IM-22977-305 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) interpro:IPR035175 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:vDMi5ExMRZu+QfhPYYmxG+0DwB09606 intact-crc:08126B7CD4C652E8|rigid:ZkrRLhTGl78sUjJAReVhhiPemhE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:Q53HC0 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-719994|uniprotkb:Q9H697|uniprotkb:B3KNQ0|ensembl:ENSP00000238156|ensembl:ENSP00000488830 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:ccd92_human(display_long)|uniprotkb:Limkain beta-2(gene name synonym)|uniprotkb:CCDC92(gene name)|psi-mi:CCDC92(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677239|imex:IM-22977-317 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_079416.1|ensembl:ENSG00000119242(gene)|ensembl:ENSG00000275035(gene)|ensembl:ENST00000238156(transcript)|ensembl:ENST00000632401(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR033224|interpro:IPR039496|interpro:IPR040370|mint:Q53HC0|refseq:NP_001291886.1|refseq:NP_001291887.1|refseq:NP_001291888.1|refseq:NP_001291889.1|refseq:NP_001291890.1|refseq:XP_005253681.1|refseq:XP_016875473.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:Iu/FzTqEpzn8N5WUTt1OwoKWxyc9606 intact-crc:4E786FFF35070CAC|rigid:+mXQgAsKwPv7YeAPcWkfB+ktYuI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:Q6ZVK8 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-740486|intact:EBI-954151|ensembl:ENSP00000480722|uniprotkb:Q9H687|uniprotkb:Q8IZ75 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:nud18_human(display_long)|uniprotkb:NUDT18(gene name)|psi-mi:NUDT18(display_short)|uniprotkb:2-hydroxy-dADP phosphatase(gene name synonym)|uniprotkb:7,8-dihydro-8-oxoguanine phosphatase(gene name synonym)|uniprotkb:MTH3(gene name synonym)|uniprotkb:MutT homolog 3(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 18(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677234|imex:IM-22977-316 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_079091.3|ensembl:ENST00000611621(transcript)|ensembl:ENSG00000275074(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0044715"(8-oxo-dGDP phosphatase activity)|go:"GO:0044716"(8-oxo-GDP phosphatase activity)|go:"GO:0044717"(8-hydroxy-dADP phosphatase activity)|go:"GO:0046057"(dADP catabolic process)|go:"GO:0046067"(dGDP catabolic process)|go:"GO:0046712"(GDP catabolic process)|go:"GO:0055086"(nucleobase-containing small molecule metabolic process)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR020476|interpro:IPR042970|rcsb pdb:3GG6|rcsb pdb:4HVY|reactome:R-HSA-2393930 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:IBrXB2HhvhcyxMTQ0Xs5hGiimzA9606 intact-crc:10858D64CDB28A40|rigid:1OtfGNqqUHqlrfZWYQ+pqAosalQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:Q8N883 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-9675993|uniprotkb:Q9BSN8|uniprotkb:Q8TCF4|uniprotkb:Q494T8|ensembl:ENSP00000270649 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:zn614_human(display_long)|uniprotkb:ZNF614(gene name)|psi-mi:ZNF614(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677229|imex:IM-22977-315 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_079316.2|ensembl:ENSG00000142556(gene)|ensembl:ENST00000270649(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:DTfWPcCHy/ZIwvALRCnGC6SMX749606 intact-crc:CA104A7B26E9233D|rigid:rCObw2hQbm9ASPbxbEzIH4N7K3I false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:Q6ZVK8 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-740486|intact:EBI-954151|ensembl:ENSP00000480722|uniprotkb:Q9H687|uniprotkb:Q8IZ75 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:nud18_human(display_long)|uniprotkb:NUDT18(gene name)|psi-mi:NUDT18(display_short)|uniprotkb:2-hydroxy-dADP phosphatase(gene name synonym)|uniprotkb:7,8-dihydro-8-oxoguanine phosphatase(gene name synonym)|uniprotkb:MTH3(gene name synonym)|uniprotkb:MutT homolog 3(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 18(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677224|imex:IM-22977-314 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_079091.3|ensembl:ENST00000611621(transcript)|ensembl:ENSG00000275074(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0044715"(8-oxo-dGDP phosphatase activity)|go:"GO:0044716"(8-oxo-GDP phosphatase activity)|go:"GO:0044717"(8-hydroxy-dADP phosphatase activity)|go:"GO:0046057"(dADP catabolic process)|go:"GO:0046067"(dGDP catabolic process)|go:"GO:0046712"(GDP catabolic process)|go:"GO:0055086"(nucleobase-containing small molecule metabolic process)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR020476|interpro:IPR042970|rcsb pdb:3GG6|rcsb pdb:4HVY|reactome:R-HSA-2393930 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:IBrXB2HhvhcyxMTQ0Xs5hGiimzA9606 intact-crc:6889D48DDA5A7B0E|rigid:1OtfGNqqUHqlrfZWYQ+pqAosalQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:Q8N5F7 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-721539|uniprotkb:Q96BQ2|uniprotkb:Q9H638|intact:EBI-745962|intact:EBI-1055594|uniprotkb:Q6IPW6|ensembl:ENSP00000360464 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:nkap_human(display_long)|uniprotkb:NKAP(gene name)|psi-mi:NKAP(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677219|imex:IM-22977-313 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_078804.2|ensembl:ENSG00000101882(gene)|ensembl:ENST00000371410(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046638"(positive regulation of alpha-beta T cell differentiation)|interpro:IPR009269(Protein of unknown function DUF926)|interpro:IPR040466|mint:Q8N5F7|rcsb pdb:6QDV psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:AiSgP+Qr12IZX1LBTsna82wmkks9606 intact-crc:DE2DF9CA2591015D|rigid:p9CUP6zkHvup9CPs3SX8gqf6Ykc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:Q96CN9 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-746252|uniprotkb:Q9H6N7|ensembl:ENSP00000318821 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:gcc1_human(display_long)|uniprotkb:Golgi coiled-coil protein 1(gene name synonym)|uniprotkb:GCC1(gene name)|psi-mi:GCC1(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677214|imex:IM-22977-312 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_078799.2|ensembl:ENSG00000179562(gene)|ensembl:ENST00000321407(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0031267"(small GTPase binding)|interpro:IPR000237(GRIP)|reactome:R-HSA-6811440|go:"GO:0000138"(Golgi trans cisterna) psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:SCI+peKjPIvl/HbUUpHGM++qiRE9606 intact-crc:CE3C7679850151FA|rigid:gDeQNnnU/SXaDQia3V+ioE8RHbw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:Q9H0B3 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-745878|uniprotkb:Q8N4G8|uniprotkb:Q96M14|uniprotkb:Q9C0I0|uniprotkb:B4DYH2|uniprotkb:E9PDE0|uniprotkb:E9PH54|uniprotkb:Q2KHR5|ensembl:ENSP00000470780 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:iqcn_human(display_long)|uniprotkb:IQCN(gene name)|psi-mi:IQCN(display_short)|uniprotkb:KIAA1683(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677259|imex:IM-22977-321 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_001138776.1|refseq:NP_001138777.1|refseq:NP_079525.1|ensembl:ENSG00000130518(gene)|ensembl:ENST00000600328(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR027417|interpro:IPR040124|refseq:XP_005260141.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:HxF5+Sq8vABdGwkzKy+JlbjLieQ9606 intact-crc:5449FAA0E6AC14E6|rigid:IIkATO5NC0Xbf2o+77NdDE11zSY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:Q8NHQ1 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677254|imex:IM-22977-320 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606 intact-crc:1090AE163D2E0A62|rigid:LoP13yR1Vt/fK6BqoTRzlk2mxDc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:Q96MT8 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-741977|uniprotkb:Q96CR0|uniprotkb:Q9H8F5|uniprotkb:Q9H8N0|uniprotkb:D3DND8|uniprotkb:D3DND9|uniprotkb:D3DNE0|ensembl:ENSP00000426129|ensembl:ENSP00000475903|ensembl:ENSP00000502085|ensembl:ENSP00000506896 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:cep63_human(display_long)|uniprotkb:CEP63(gene name)|psi-mi:CEP63(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677249|imex:IM-22977-319 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) go:"GO:0000922"(spindle pole)|go:"GO:0005829"(cytosol)|refseq:NP_001035842.1|refseq:NP_001035843.1|refseq:NP_001035859.1|refseq:NP_079456.2|ensembl:ENSG00000182923(gene)|ensembl:ENST00000513612(transcript)|ensembl:ENST00000606977(transcript)|ensembl:ENST00000675561(transcript)|ensembl:ENST00000683596(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005814"(centriole)|go:"GO:0005813"(centrosome)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|interpro:IPR029608|interpro:IPR031470|mint:Q96MT8|rcsb pdb:6CSU|rcsb pdb:6CSV|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|go:"GO:0007099"(centriole replication)|refseq:XP_011511496.1|refseq:XP_005247854.1|refseq:XP_006713823.1|refseq:XP_016862743.1|refseq:XP_016862744.1|refseq:XP_016862745.1|refseq:XP_016862751.1|refseq:XP_016862752.1|refseq:XP_016862753.1|refseq:XP_016862755.1|refseq:XP_016862756.1|dip:DIP-36374N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:/WPfint+sTGNCYCH9XG5rPYSOm09606 intact-crc:24ED75CA09CAAE1A|rigid:95RNNJDoRmBJ84J5mCX6GqbxkMA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:Q96MT8 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-741977|uniprotkb:Q96CR0|uniprotkb:Q9H8F5|uniprotkb:Q9H8N0|uniprotkb:D3DND8|uniprotkb:D3DND9|uniprotkb:D3DNE0|ensembl:ENSP00000426129|ensembl:ENSP00000475903|ensembl:ENSP00000502085|ensembl:ENSP00000506896 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:cep63_human(display_long)|uniprotkb:CEP63(gene name)|psi-mi:CEP63(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677244|imex:IM-22977-318 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) go:"GO:0000922"(spindle pole)|go:"GO:0005829"(cytosol)|refseq:NP_001035842.1|refseq:NP_001035843.1|refseq:NP_001035859.1|refseq:NP_079456.2|ensembl:ENSG00000182923(gene)|ensembl:ENST00000513612(transcript)|ensembl:ENST00000606977(transcript)|ensembl:ENST00000675561(transcript)|ensembl:ENST00000683596(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005814"(centriole)|go:"GO:0005813"(centrosome)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|interpro:IPR029608|interpro:IPR031470|mint:Q96MT8|rcsb pdb:6CSU|rcsb pdb:6CSV|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|go:"GO:0007099"(centriole replication)|refseq:XP_011511496.1|refseq:XP_005247854.1|refseq:XP_006713823.1|refseq:XP_016862743.1|refseq:XP_016862744.1|refseq:XP_016862745.1|refseq:XP_016862751.1|refseq:XP_016862752.1|refseq:XP_016862753.1|refseq:XP_016862755.1|refseq:XP_016862756.1|dip:DIP-36374N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:/WPfint+sTGNCYCH9XG5rPYSOm09606 intact-crc:5CE12C231E225F54|rigid:95RNNJDoRmBJ84J5mCX6GqbxkMA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:Q9BRK4 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-741037|ensembl:ENSP00000359240|ensembl:ENSP00000359243|uniprotkb:Q8N3I0|uniprotkb:Q96J79|uniprotkb:Q96JL2|uniprotkb:B1AL14|uniprotkb:D3DR72 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:lzts2_human(display_long)|uniprotkb:Protein LAPSER1(gene name synonym)|uniprotkb:LZTS2(gene name)|psi-mi:LZTS2(display_short)|uniprotkb:KIAA1813(gene name synonym)|uniprotkb:LAPSER1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677279|imex:IM-22977-325 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_115805.1|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:0031982"(vesicle)|go:"GO:0051013"(microtubule severing)|go:"GO:0051168"(nuclear export)|go:"GO:0051255"(spindle midzone assembly)|go:"GO:0060682"(primary ureteric bud growth)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR028597|mint:Q9BRK4|ensembl:ENSG00000107816(gene)|ensembl:ENST00000370220(transcript)|ensembl:ENST00000370223(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|refseq:XP_016872269.1|refseq:NP_001305028.1|refseq:NP_001305029.1|refseq:NP_001305030.1|refseq:XP_005270279.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:OaMJmnmfm6JniKUJeyg7fS6zRcw9606 intact-crc:059E7B904F092766|rigid:96c8F/VbsYsCoq7CtyIRoF8qkJc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:Q9BRK4 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-741037|ensembl:ENSP00000359240|ensembl:ENSP00000359243|uniprotkb:Q8N3I0|uniprotkb:Q96J79|uniprotkb:Q96JL2|uniprotkb:B1AL14|uniprotkb:D3DR72 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:lzts2_human(display_long)|uniprotkb:Protein LAPSER1(gene name synonym)|uniprotkb:LZTS2(gene name)|psi-mi:LZTS2(display_short)|uniprotkb:KIAA1813(gene name synonym)|uniprotkb:LAPSER1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677274|imex:IM-22977-324 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_115805.1|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:0031982"(vesicle)|go:"GO:0051013"(microtubule severing)|go:"GO:0051168"(nuclear export)|go:"GO:0051255"(spindle midzone assembly)|go:"GO:0060682"(primary ureteric bud growth)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR028597|mint:Q9BRK4|ensembl:ENSG00000107816(gene)|ensembl:ENST00000370220(transcript)|ensembl:ENST00000370223(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|refseq:XP_016872269.1|refseq:NP_001305028.1|refseq:NP_001305029.1|refseq:NP_001305030.1|refseq:XP_005270279.1 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:OaMJmnmfm6JniKUJeyg7fS6zRcw9606 intact-crc:7D92227958E1D628|rigid:96c8F/VbsYsCoq7CtyIRoF8qkJc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:Q9BRJ6 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-751612|ensembl:ENSP00000350011|ensembl:ENSP00000380286|ensembl:ENSP00000380288 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:cg050_human(display_long)|uniprotkb:FP15621(orf name)|uniprotkb:C7orf50(gene name)|psi-mi:C7orf50(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677269|imex:IM-22977-323 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_001127867.1|refseq:NP_001127868.1|refseq:NP_115726.1|refseq:NP_001305181.1|ensembl:ENSG00000146540(gene)|ensembl:ENST00000357429(transcript)|ensembl:ENST00000397098(transcript)|ensembl:ENST00000397100(transcript)|interpro:IPR019327|mint:Q9BRJ6|go:"GO:0003723"(RNA binding) psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:POftCOri0Nj8YUd5Kc3nNMDb41A9606 intact-crc:3D86E1285EF14DA5|rigid:YdXIAWfPaUg+GBbWa5gbA7IFMl4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:Q9Y6D9 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-742610|uniprotkb:B3KR41|uniprotkb:Q9UNH0|uniprotkb:Q13312|uniprotkb:Q75MI0|uniprotkb:Q86UM4|ensembl:ENSP00000265854|ensembl:ENSP00000382562|ensembl:ENSP00000385334 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:md1l1_human(display_long)|uniprotkb:Mitotic arrest deficient 1-like protein 1(gene name synonym)|uniprotkb:Mitotic checkpoint MAD1 protein homolog(gene name synonym)|uniprotkb:Tax-binding protein 181(gene name synonym)|uniprotkb:MAD1L1(gene name)|psi-mi:MAD1L1(display_short)|uniprotkb:MAD1(gene name synonym)|uniprotkb:TXBP181(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677264|imex:IM-22977-322 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_001013858.1|refseq:NP_001013859.1|refseq:NP_003541.2|refseq:NP_001291452.1|refseq:NP_001291453.1|ensembl:ENSG00000002822(gene)|ensembl:ENST00000265854(transcript)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|interpro:IPR008672(Mitotic checkpoint)|mint:Q9Y6D9|rcsb pdb:1GO4|rcsb pdb:4DZO|rcsb pdb:7B1F|rcsb pdb:7B1H|rcsb pdb:7B1J|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENST00000399654(transcript)|ensembl:ENST00000406869(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043515"(kinetochore binding)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0048538"(thymus development)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|refseq:XP_005249934.1|dip:DIP-29654N psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:9CcqpZlN0IgqC939rIo7vNgOvLQ9606 intact-crc:CA77987B721D2B86|rigid:A4O2lRO9MdWvEx4dU4LSkwWMY2w false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:Q9UJX2 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-396137|uniprotkb:O75433|uniprotkb:Q9BS73|uniprotkb:B4E3A2|uniprotkb:B7WP05|uniprotkb:Q53FN2|uniprotkb:A8K6E5|uniprotkb:D3DQB7|ensembl:ENSP00000378350 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:cdc23_human(display_long)|uniprotkb:CDC23(gene name)|psi-mi:CDC23(display_short)|uniprotkb:ANAPC8(gene name synonym)|uniprotkb:Anaphase-promoting complex subunit 8(gene name synonym)|uniprotkb:Cyclosome subunit 8(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677309|imex:IM-22977-331 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_004652.2|dip:DIP-32959N|ensembl:ENSG00000094880(gene)|ensembl:ENST00000394886(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007091"(metaphase/anaphase transition of mitotic cell cycle)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR007192(Cdc23)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q9UJX2|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:uTZL2UHzZHLoKnio/1LcuSzZpW09606 intact-crc:C308C8A99B6AF257|rigid:PueJEhUoqfReAh4G02gJ+L0/XE8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:O14503 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-711810|uniprotkb:Q96TD3|ensembl:ENSP00000256495 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:bhe40_human(display_long)|uniprotkb:BHLHE40(gene name)|psi-mi:BHLHE40(display_short)|uniprotkb:Differentially expressed in chondrocytes protein 1(gene name synonym)|uniprotkb:Enhancer-of-split and hairy-related protein 2(gene name synonym)|uniprotkb:Stimulated by retinoic acid gene 13 protein(gene name synonym)|uniprotkb:BHLHB2(gene name synonym)|uniprotkb:DEC1(gene name synonym)|uniprotkb:SHARP2(gene name synonym)|uniprotkb:STRA13(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677304|imex:IM-22977-330 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) ensembl:ENSG00000134107(gene)|ensembl:ENST00000256495(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016604"(nuclear body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043426"(MRF binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|refseq:NP_003661.1|dip:DIP-36698N|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:O14503|reactome:R-HSA-1368108 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:JZrZ1Yo2PF33s9Lf8rLTHCqoptk9606 intact-crc:143EA574AF7C7E0F|rigid:zeSfVTS3SGpmz8h80EoQrhf7+G4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:Q9BY27 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-742953|ensembl:ENSP00000248879|uniprotkb:Q9BW33|uniprotkb:A8K1N7|uniprotkb:D3DX29|uniprotkb:B3KMC0 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:dgc6l_human(display_long)|uniprotkb:DiGeorge syndrome critical region 6-like protein(gene name synonym)|uniprotkb:DGCR6L(gene name)|psi-mi:DGCR6L(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677299|imex:IM-22977-329 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) go:"GO:0005634"(nucleus)|interpro:IPR010849(DiGeorge syndrome critical 6)|ensembl:ENSG00000128185(gene)|ensembl:ENST00000248879(transcript)|refseq:NP_150282.2 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:kgKOLihCtc75qwW051IZsGLspI09606 intact-crc:B6F29FD5B70AF458|rigid:yTAL/g6T3p01kWoPB364cDPj/og false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:Q6P1W5 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-946029|uniprotkb:B3KVT1|uniprotkb:Q96IC8|ensembl:ENSP00000435634|uniprotkb:D3DPR3|uniprotkb:E9PJ76 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:ca094_human(display_long)|uniprotkb:C1orf94(gene name)|psi-mi:C1orf94(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677294|imex:IM-22977-328 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_001128206.1|refseq:NP_116273.2|ensembl:ENSG00000142698(gene)|ensembl:ENST00000488417(transcript)|interpro:IPR031496 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:y1o4xWvTl2CBA1J7jsP7y8ZjLzM9606 intact-crc:FBD7E36B39280368|rigid:PzKsqQma60N7HsrFtZi4oMlw/5k false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:Q8IUF8 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-751580|uniprotkb:Q6AHW4|uniprotkb:Q6SKS0|uniprotkb:Q8IU69|uniprotkb:Q8IUF6|uniprotkb:Q8IUF7|uniprotkb:Q96KB0|uniprotkb:Q96C17|uniprotkb:D3DN35|ensembl:ENSP00000328251|ensembl:ENSP00000377748 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:riox2_human(display_long)|uniprotkb:RIOX2(gene name)|psi-mi:RIOX2(display_short)|uniprotkb:60S ribosomal protein L27a histidine hydroxylase(gene name synonym)|uniprotkb:Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA(gene name synonym)|uniprotkb:Histone lysine demethylase MINA(gene name synonym)|uniprotkb:MDIG(gene name synonym)|uniprotkb:MINA(gene name synonym)|uniprotkb:MINA53(gene name synonym)|uniprotkb:MYC-induced nuclear antigen(gene name synonym)|uniprotkb:Mineral dust-induced gene protein(gene name synonym)|uniprotkb:NO52(gene name synonym)|uniprotkb:Nucleolar protein 52(gene name synonym)|uniprotkb:Ribosomal oxygenase MINA(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677289|imex:IM-22977-327 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_001035998.1|refseq:NP_116167.3|refseq:NP_694822.2|refseq:NP_001248758.1|refseq:XP_005247895.1|dip:DIP-28141N|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR039994|mint:Q8IUF8|rcsb pdb:2XDV|rcsb pdb:4BU2|rcsb pdb:4BXF|reactome:R-HSA-3214842|ensembl:ENSG00000170854(gene)|ensembl:ENST00000333396(transcript)|ensembl:ENST00000394198(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity) psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:tdjUsv9EuHn+AADASjfGu9U15Xc9606 intact-crc:251C65EAD979FA09|rigid:8Ej0GGy0Jk6seRL3fySbBcP+s4I false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:Q9BSW2 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-739773|uniprotkb:B4E1X0|uniprotkb:B9EK63|ensembl:ENSP00000409382 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:efc4b_human(display_long)|uniprotkb:CRACR2A(gene name)|psi-mi:CRACR2A(display_short)|uniprotkb:Calcium release-activated calcium channel regulator 2A(gene name synonym)|uniprotkb:Calcium release-activated channel regulator 2A(gene name synonym)|uniprotkb:EFCAB4B(gene name synonym)|uniprotkb:RAB46(gene name synonym)|uniprotkb:Ras-related protein Rab-46(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677284|imex:IM-22977-326 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_001138430.1|refseq:NP_116069.1|ensembl:ENSG00000130038(gene)|ensembl:ENST00000440314(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001772"(immunological synapse)|go:"GO:0002115"(store-operated calcium entry)|go:"GO:0002250"(adaptive immune response)|go:"GO:0003924"(GTPase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0031982"(vesicle)|go:"GO:0032237"(activation of store-operated calcium channel activity)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0034776"(response to histamine)|go:"GO:0035580"(specific granule lumen)|go:"GO:0045063"(T-helper 1 cell differentiation)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0051928"(positive regulation of calcium ion transport)|interpro:IPR001806(Ras GTPase)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|rcsb pdb:6PSD|reactome:R-HSA-6798695|interpro:IPR027417 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2021/04/12 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:IjhHTze6Dftzv9JltvNQgdATG+89606 intact-crc:F59C36F8D4FBBBB9|rigid:H72ss0pTZK5bFaAc2NLqCt2tX9U false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:O00189 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-3914106|ensembl:ENSP00000352603|ensembl:ENSP00000412185|uniprotkb:Q8WV65|uniprotkb:Q9UHK9|uniprotkb:D6W5U1 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:ap4m1_human(display_long)|uniprotkb:AP4M1(gene name)|psi-mi:AP4M1(display_short)|uniprotkb:MUARP2(gene name synonym)|uniprotkb:Mu subunit of AP-4(gene name synonym)|uniprotkb:Mu-adaptin-related protein 2(gene name synonym)|uniprotkb:Mu4-adaptin(gene name synonym)|uniprotkb:AP-4 adaptor complex mu subunit(gene name synonym)|uniprotkb:Adaptor-related protein complex 4 subunit mu-1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677334|imex:IM-22977-336 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) ensembl:ENSG00000221838(gene)|ensembl:ENST00000359593(transcript)|ensembl:ENST00000421755(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0008104"(protein localization)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030124"(AP-4 adaptor complex)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0031410"(cytoplasmic vesicle)|refseq:NP_004713.2|go:"GO:0031904"(endosome lumen)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090160"(Golgi to lysosome transport)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR001392(Clathrin adaptor, mu subunit)|interpro:IPR011012(Longin-like)|interpro:IPR018240|interpro:IPR022775|interpro:IPR028565|interpro:IPR036168|rcsb pdb:3L81|rcsb pdb:4MDR|reactome:R-HSA-432720 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:yAnydsX4RFJWI43arkgC7OcCUfM9606 intact-crc:6C31D28D5CFD7020|rigid:lSMcOA9ItLA5Gkny3PDGkonXrBw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:O14964 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677329|imex:IM-22977-335 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606 intact-crc:6C339DA3C8188F41|rigid:JRIG9zjTKInXfmKKer0WW9WQ4bU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:O14964 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677324|imex:IM-22977-334 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606 intact-crc:143FC44ADFF07E0F|rigid:JRIG9zjTKInXfmKKer0WW9WQ4bU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:Q8TAE8 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-372506|uniprotkb:Q8IVM3|uniprotkb:Q8TE51|uniprotkb:Q969P9|uniprotkb:Q9BSM6|intact:EBI-28983431|ensembl:ENSP00000323065 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:g45ip_human(display_long)|uniprotkb:39S ribosomal protein L59, mitochondrial(gene name synonym)|uniprotkb:MRPL59(gene name synonym)|uniprotkb:CR6-interacting factor 1(gene name synonym)|uniprotkb:CKII beta-associating protein(gene name synonym)|uniprotkb:Papillomavirus L2-interacting nuclear protein 1(gene name synonym)|uniprotkb:p53-responsive gene 6 protein(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL64(gene name synonym)|uniprotkb:GADD45GIP1(gene name)|psi-mi:GADD45GIP1(display_short)|uniprotkb:PLINP1(gene name synonym)|uniprotkb:PRG6(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677319|imex:IM-22977-333 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_443082.2|ensembl:ENSP00000323065|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|ensembl:ENSG00000179271(gene)|ensembl:ENST00000316939(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005840"(ribosome)|go:"GO:0007049"(cell cycle)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR018472|interpro:IPR043035|mint:Q8TAE8|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:lFY+2Pev2sxqaW9nhzemL0QO52s9606 intact-crc:8F76E10BD5F21E42|rigid:OZXxVdZr2ds4yhNEbcKc+v1KJWw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:Q969F0 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-743099|ensembl:ENSP00000359375 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:fate1_human(display_long)|uniprotkb:Tumor antigen BJ-HCC-2(gene name synonym)|uniprotkb:Cancer/testis antigen 43(gene name synonym)|uniprotkb:FATE1(gene name)|psi-mi:FATE1(display_short)|uniprotkb:FATE(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677314|imex:IM-22977-332 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_149076.1|ensembl:ENSG00000147378(gene)|ensembl:ENST00000370350(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|interpro:IPR039153|interpro:IPR039433|mint:Q969F0 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:Nm1N6lO92MHr5rIKC007oouF5RE9606 intact-crc:82AB7380A45160F3|rigid:iPiOWoAK8YcOYXaqVvYEQVMFdNQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:P51116 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677344|imex:IM-22977-338 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606 intact-crc:8FD108A74707CE63|rigid:85NnTT7HdQxPldXkFEuPqFPMbA0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03410 uniprotkb:Q92530 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-945916|uniprotkb:A0AVQ9|uniprotkb:Q9H4I1|uniprotkb:D3DVW3|ensembl:ENSP00000327704|ensembl:ENSP00000338039 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:psmf1_human(display_long)|uniprotkb:PSMF1(gene name)|psi-mi:PSMF1(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677339|imex:IM-22977-337 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_006805.2|refseq:NP_848693.2|refseq:NP_001310336.1|ensembl:ENSG00000125818(gene)|ensembl:ENST00000333082(transcript)|ensembl:ENST00000335877(transcript)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070628"(proteasome binding)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|interpro:IPR013886(PI31 proteasome regulator)|interpro:IPR021625|rcsb pdb:2VT8|rcsb pdb:4OUH|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 psi-mi:"MI:0471"(mint) - - figure legend:ST2 ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:QufCMzFs9wZBQO5l4iVOfn4dnvc9606 intact-crc:52F26874DE52B7C4|rigid:6hrYTXiOPf45YCa8P2E7/It9CwM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q2Q067 uniprotkb:P02794 intact:EBI-9675545 intact:EBI-713259|uniprotkb:Q3KRA8|uniprotkb:Q3SWW1|ensembl:ENSP00000273550|ensembl:ENSP00000484477|uniprotkb:B3KNR5 psi-mi:q2q067_9dela(display_long)|uniprotkb:HBZ(gene name)|psi-mi:HBZ(display_short) psi-mi:frih_human(display_long)|uniprotkb:Cell proliferation-inducing gene 15 protein(gene name synonym)|uniprotkb:FTH1(gene name)|psi-mi:FTH1(display_short)|uniprotkb:FTH(gene name synonym)|uniprotkb:FTHL6(gene name synonym)|uniprotkb:PIG15(orf name)|uniprotkb:OK/SW-cl.84(orf name) psi-mi:"MI:0231"(mammalian protein protein interaction trap) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11908(humt-)|taxid:11908(Human T-lymphotropic virus 1) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677356|imex:IM-22977-339 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6DNQ|interpro:IPR026220|go:"GO:0016032"(viral process) refseq:NP_002023.2|ensembl:ENSG00000167996(gene)|ensembl:ENST00000273550(transcript)|ensembl:ENST00000620041(transcript)|go:"GO:0004322"(ferroxidase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006880"(intracellular sequestering of iron ion)|go:"GO:0006955"(immune response)|go:"GO:0008043"(intracellular ferritin complex)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008199"(ferric iron binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0044754"(autolysosome)|mint:P02794|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:1FHA|rcsb pdb:2CEI|rcsb pdb:2CHI|rcsb pdb:2CIH|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001519(Ferritin, N-terminal)|interpro:IPR008331(Ferritin and Dps)|interpro:IPR009040(Ferritin-like)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR012347(Ferritin-related)|interpro:IPR014034(Ferritin, conserved site)|rcsb pdb:2CLU|rcsb pdb:2CN6|rcsb pdb:2CN7|rcsb pdb:2FHA|rcsb pdb:2IU2|rcsb pdb:2Z6M|rcsb pdb:3AJO|rcsb pdb:3AJP|rcsb pdb:3AJQ|rcsb pdb:3ERZ|rcsb pdb:3ES3|rcsb pdb:4DYX|rcsb pdb:4DYY|rcsb pdb:4DYZ|rcsb pdb:4Y08|rcsb pdb:4YKH|rcsb pdb:4ZJK|rcsb pdb:5CMQ|rcsb pdb:5CMR|rcsb pdb:5GN8|rcsb pdb:5GOU|rcsb pdb:5JKK|rcsb pdb:5JKL|rcsb pdb:5JKM|rcsb pdb:5N26|rcsb pdb:5N27|rcsb pdb:5UP7|rcsb pdb:5UP8|rcsb pdb:5UP9|rcsb pdb:5VTD|rcsb pdb:5XB1|rcsb pdb:5YI5|rcsb pdb:5ZND|rcsb pdb:6B8F|rcsb pdb:6B8G|rcsb pdb:4DZ0|rcsb pdb:6FTV|rcsb pdb:6GSR|rcsb pdb:6H5I|rcsb pdb:6H6T|rcsb pdb:6H6U|rcsb pdb:6IPC|rcsb pdb:6IPO|rcsb pdb:6IPP|rcsb pdb:6IPQ|rcsb pdb:6J4A|rcsb pdb:6J7G|rcsb pdb:6JOB|rcsb pdb:6JPS|rcsb pdb:6KE2|rcsb pdb:6KE4|rcsb pdb:4OYN|rcsb pdb:6M52|rcsb pdb:6M54|rcsb pdb:6WYF|rcsb pdb:6WYG|rcsb pdb:6WYH|rcsb pdb:6Z6U|rcsb pdb:6Z9E|rcsb pdb:6Z9F|rcsb pdb:7A6A|rcsb pdb:7A6B|rcsb pdb:7CK8|rcsb pdb:7CK9|rcsb pdb:7JGK|rcsb pdb:7JGL|rcsb pdb:7JGM|rcsb pdb:7JGN|rcsb pdb:7JGO|rcsb pdb:7JGP|rcsb pdb:7JGQ|rcsb pdb:7K26|rcsb pdb:7K3V|rcsb pdb:7K3W|reactome:R-HSA-3000480|reactome:R-HSA-432722|reactome:R-HSA-6798695|reactome:R-HSA-917937|dip:DIP-38301N psi-mi:"MI:0471"(mint) - - figure legend:ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/07/21 2014/10/16 rogid:j9b0X2J4Nu0iW1SeHJj8GlrL3IE11908 rogid:TchHgRpv+inA8BQ5i0OHaa267tQ9606 intact-crc:7BD2DC7DFF1035E8|rigid:VYNMsot3bR90yEWhV8bCJBDq9y0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q2Q067 uniprotkb:Q9UH92 intact:EBI-9675545 intact:EBI-741109|intact:EBI-28976799|ensembl:ENSP00000246912|uniprotkb:Q53XM6|uniprotkb:Q96FL2|uniprotkb:Q9H2V0|uniprotkb:Q9H2V1|uniprotkb:Q9H2V2|uniprotkb:Q9NXN3|uniprotkb:B2RAV8|uniprotkb:A8K2J3|uniprotkb:B2RD73 psi-mi:q2q067_9dela(display_long)|uniprotkb:HBZ(gene name)|psi-mi:HBZ(display_short) psi-mi:mlx_human(display_long)|uniprotkb:Max-like bHLHZip protein(gene name synonym)|uniprotkb:BHLHD13(gene name synonym)|uniprotkb:Protein BigMax(gene name synonym)|uniprotkb:Transcription factor-like protein 4(gene name synonym)|uniprotkb:MLX(gene name)|psi-mi:MLX(display_short)|uniprotkb:TCFL4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 13(gene name synonym) psi-mi:"MI:0231"(mammalian protein protein interaction trap) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11908(humt-)|taxid:11908(Human T-lymphotropic virus 1) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677361|imex:IM-22977-340 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6DNQ|interpro:IPR026220|go:"GO:0016032"(viral process) refseq:NP_733752.1|refseq:NP_937847.1|refseq:NP_937848.1|ensembl:ENSG00000108788(gene)|ensembl:ENST00000246912(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR032647|interpro:IPR036638|reactome:R-HSA-163765|go:"GO:0005654"(nucleoplasm)|ensembl:ENSP00000246912|ensembl:ENST00000346833|ensembl:ENSP00000320913|ensembl:ENST00000435881|ensembl:ENSP00000416627 psi-mi:"MI:0471"(mint) - - figure legend:ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/07/21 2014/10/16 rogid:j9b0X2J4Nu0iW1SeHJj8GlrL3IE11908 rogid:5zIr/dC+5Gre7BiEy/8g0MEdppY9606 intact-crc:B8F941FE9612D4BB|rigid:qa+eFixyWgLr29JX/uHLc0Sjnik false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C206 uniprotkb:O14503 intact:EBI-9675596|uniprotkb:O56230 intact:EBI-711810|uniprotkb:Q96TD3|ensembl:ENSP00000256495 psi-mi:rex_htl1c(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-1(gene name synonym)|uniprotkb:p27Rex(gene name synonym) psi-mi:bhe40_human(display_long)|uniprotkb:BHLHE40(gene name)|psi-mi:BHLHE40(display_short)|uniprotkb:Differentially expressed in chondrocytes protein 1(gene name synonym)|uniprotkb:Enhancer-of-split and hairy-related protein 2(gene name synonym)|uniprotkb:Stimulated by retinoic acid gene 13 protein(gene name synonym)|uniprotkb:BHLHB2(gene name synonym)|uniprotkb:DEC1(gene name synonym)|uniprotkb:SHARP2(gene name synonym)|uniprotkb:STRA13(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 2(gene name synonym) psi-mi:"MI:0231"(mammalian protein protein interaction trap) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677376|imex:IM-22977-343 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1EXY|refseq:NP_057863.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) ensembl:ENSG00000134107(gene)|ensembl:ENST00000256495(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016604"(nuclear body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043426"(MRF binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|refseq:NP_003661.1|dip:DIP-36698N|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:O14503|reactome:R-HSA-1368108 psi-mi:"MI:0471"(mint) - - figure legend:ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/07/21 2014/11/02 rogid:Jg3y2XqUP/JBerfBYcxMesTuQFQ11927 rogid:JZrZ1Yo2PF33s9Lf8rLTHCqoptk9606 intact-crc:E73C5381CE59F59B|rigid:ghLwRctQMwqQcdiD+Lnej6Zuh+w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C206 uniprotkb:Q6PF05 intact:EBI-9675596|uniprotkb:O56230 intact:EBI-8656864|ensembl:ENSP00000422188|uniprotkb:Q96LJ2|intact:MINT-8163808|uniprotkb:Q6RGS4|uniprotkb:Q8N7R3|uniprotkb:G8IJH6 psi-mi:rex_htl1c(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-1(gene name synonym)|uniprotkb:p27Rex(gene name synonym) psi-mi:tt23l_human(display_long)|uniprotkb:TTC23L(gene name)|psi-mi:TTC23L(display_short) psi-mi:"MI:0231"(mammalian protein protein interaction trap) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677371|imex:IM-22977-342 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1EXY|refseq:NP_057863.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) ensembl:ENSG00000205838(gene)|ensembl:ENST00000505624(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0030496"(midbody)|go:"GO:0034976"(response to endoplasmic reticulum stress)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR042621|mint:Q6PF05|refseq:NP_001304878.1|refseq:NP_653326.3 psi-mi:"MI:0471"(mint) - comment:mint figure legend:ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/07/21 2014/11/02 rogid:Jg3y2XqUP/JBerfBYcxMesTuQFQ11927 rogid:SRndoUysST7RgIovvs89vd30vMk9606 intact-crc:D7E36F4E11F66A6A|rigid:ZAN3rdneLPDamL9kMFNrIq2H8bs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C206 uniprotkb:Q96FJ2 intact:EBI-9675596|uniprotkb:O56230 intact:EBI-742371|uniprotkb:B2R5B4|ensembl:ENSP00000477310 psi-mi:rex_htl1c(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-1(gene name synonym)|uniprotkb:p27Rex(gene name synonym) psi-mi:dyl2_human(display_long)|uniprotkb:DYNLL2(gene name)|psi-mi:DYNLL2(display_short)|uniprotkb:Dynein light chain LC8-type 2(gene name synonym)|uniprotkb:DLC2(gene name synonym)|uniprotkb:8 kDa dynein light chain b(gene name synonym) psi-mi:"MI:0231"(mammalian protein protein interaction trap) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677366|imex:IM-22977-341 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1EXY|refseq:NP_057863.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) go:"GO:0005813"(centrosome)|refseq:NP_542408.1|ensembl:ENSG00000264364(gene)|ensembl:ENST00000579991(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0007017"(microtubule-based process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0030286"(dynein complex)|go:"GO:0031475"(myosin V complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097542"(ciliary tip)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:Q96FJ2|rcsb pdb:2XQQ|rcsb pdb:3P8M|rcsb pdb:4D07|reactome:R-HSA-139910|reactome:R-HSA-141444|reactome:R-HSA-1632852|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-5620924|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025 psi-mi:"MI:0471"(mint) - - figure legend:ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/07/21 2014/11/02 rogid:Jg3y2XqUP/JBerfBYcxMesTuQFQ11927 rogid:4RFpJF40RBja5mOvt/aCv3miiDU9606 intact-crc:5E3A9C2585D8DD58|rigid:Nh0EMng3CiDDBeEjvC43fAW+OyU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43268 uniprotkb:P14079 intact:EBI-6447147|ensembl:ENSP00000321835|ensembl:ENSP00000377273|ensembl:ENSP00000465718|uniprotkb:B7Z5J3|uniprotkb:B7Z9J6|uniprotkb:Q96AW9|uniprotkb:A8K314 intact:EBI-9675698|uniprotkb:O56231 psi-mi:etv4_human(display_long)|uniprotkb:Adenovirus E1A enhancer-binding protein(gene name synonym)|uniprotkb:E1A-F(gene name synonym)|uniprotkb:E1AF(gene name synonym)|uniprotkb:PEA3(gene name synonym)|uniprotkb:Polyomavirus enhancer activator 3 homolog(gene name synonym)|uniprotkb:ETV4(gene name)|psi-mi:ETV4(display_short) psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:"MI:0231"(mammalian protein protein interaction trap) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677396|imex:IM-22977-347 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000175832(gene)|ensembl:ENST00000319349(transcript)|ensembl:ENST00000393664(transcript)|ensembl:ENST00000591713(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030154"(cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR006715(PEA3-type ETS-domain transcription factor, N-terminal)|interpro:IPR036388|interpro:IPR036390|rcsb pdb:4UUV|rcsb pdb:5ILU|reactome:R-HSA-5687128|rcsb pdb:4CO8|refseq:NP_001073143.1|refseq:NP_001248366.1|refseq:NP_001248367.1|refseq:NP_001977.1|refseq:NP_001248368.1|dip:DIP-748N interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) psi-mi:"MI:0471"(mint) - - figure legend:ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/07/21 2014/11/02 rogid:9CuoBGjLzbo93LSm5yNFuBQlATg9606 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 intact-crc:5278E8531F4CD240|rigid:aSIvNfO1eP2MzxNUKXk5HD5e8uQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6PF05 uniprotkb:P14079 intact:EBI-8656864|ensembl:ENSP00000422188|uniprotkb:Q96LJ2|intact:MINT-8163808|uniprotkb:Q6RGS4|uniprotkb:Q8N7R3|uniprotkb:G8IJH6 intact:EBI-9675698|uniprotkb:O56231 psi-mi:tt23l_human(display_long)|uniprotkb:TTC23L(gene name)|psi-mi:TTC23L(display_short) psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:"MI:0231"(mammalian protein protein interaction trap) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677391|imex:IM-22977-346 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000205838(gene)|ensembl:ENST00000505624(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0030496"(midbody)|go:"GO:0034976"(response to endoplasmic reticulum stress)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR042621|mint:Q6PF05|refseq:NP_001304878.1|refseq:NP_653326.3 interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) psi-mi:"MI:0471"(mint) comment:mint - figure legend:ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/07/21 2014/11/02 rogid:SRndoUysST7RgIovvs89vd30vMk9606 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 intact-crc:9E2F632F11F52E82|rigid:Tle3OnFVOzKeBMVeCotXaOD/ixI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5T8I9 uniprotkb:P14079 intact:EBI-9675710|uniprotkb:Q96NN0|uniprotkb:B1AM16|uniprotkb:B1AM17|uniprotkb:Q96EJ7|uniprotkb:A8MRR6|ensembl:ENSP00000359049|ensembl:ENSP00000385655|ensembl:ENSP00000499017 intact:EBI-9675698|uniprotkb:O56231 psi-mi:henmt_human(display_long)|uniprotkb:HENMT1(gene name)|psi-mi:HENMT1(display_short)|uniprotkb:C1orf59(gene name synonym)|uniprotkb:HEN1 methyltransferase homolog 1(gene name synonym) psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:"MI:0231"(mammalian protein protein interaction trap) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677386|imex:IM-22977-345 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001096062.1|refseq:NP_653185.2|ensembl:ENSG00000162639(gene)|ensembl:ENST00000370032(transcript)|ensembl:ENST00000402983(transcript)|ensembl:ENST00000651461(transcript)|go:"GO:0001510"(RNA methylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008171"(O-methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0034587"(piRNA metabolic process)|go:"GO:0043186"(P granule)|go:"GO:0046872"(metal ion binding)|go:"GO:0090486"(small RNA 2'-O-methyltransferase)|interpro:IPR026610|interpro:IPR029063|rcsb pdb:4XCX|rcsb pdb:5WY0|reactome:R-HSA-5601884 interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) psi-mi:"MI:0471"(mint) - - figure legend:ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/07/21 2014/11/02 rogid:UXyyHUVxIewQH/NZwBful5PQcvc9606 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 intact-crc:30FDC5865818CEAE|rigid:Y+xqm/GixGdNWYkZ1cq8BBVqe7k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:O14595 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-2802973|uniprotkb:Q6NZY3|uniprotkb:Q9UEX1|uniprotkb:A8K5H4|uniprotkb:Q53ZR2|ensembl:ENSP00000381148 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:ctds2_human(display_long)|uniprotkb:NIF2(gene name synonym)|uniprotkb:OS4(gene name synonym)|uniprotkb:SCP2(gene name synonym)|uniprotkb:Nuclear LIM interactor-interacting factor 2(gene name synonym)|uniprotkb:Protein OS-4(gene name synonym)|uniprotkb:Small C-terminal domain phosphatase 2(gene name synonym)|uniprotkb:Small CTD phosphatase 2(gene name synonym)|uniprotkb:CTDSP2(gene name)|psi-mi:CTDSP2(display_short) psi-mi:"MI:0231"(mammalian protein protein interaction trap) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677381|imex:IM-22977-344 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_005721.3|interpro:IPR011948(Dullard-like phosphatase domain)|interpro:IPR023214|interpro:IPR036412|interpro:IPR040078|mint:O14595|rcsb pdb:2Q5E|reactome:R-HSA-381038|ensembl:ENSG00000175215(gene)|ensembl:ENST00000398073(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008420"(RNA polymerase II CTD heptapeptide repeat phosphatase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR004274(NLI interacting factor)|dip:DIP-61245N psi-mi:"MI:0471"(mint) - - figure legend:ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:aYyUZE/wrtAyE4rMDaGGO8pNkYw9606 intact-crc:75C2731DBC448296|rigid:/M5HrXG7bQFk58qqPumO178/aCU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:O15287 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-81610|ensembl:ENSP00000367910 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:fancg_human(display_long)|uniprotkb:FANCG(gene name)|psi-mi:FANCG(display_short)|uniprotkb:XRCC9(gene name synonym)|uniprotkb:DNA repair protein XRCC9(gene name synonym) psi-mi:"MI:0231"(mammalian protein protein interaction trap) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677401|imex:IM-22977-348 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) ensembl:ENSG00000221829(gene)|refseq:NP_004620.1|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007286"(spermatid development)|go:"GO:0009314"(response to radiation)|ensembl:ENST00000378643(transcript)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0043240"(Fanconi anaemia nuclear complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039684|mint:O15287|rcsb pdb:7KZP|rcsb pdb:7KZQ|go:"GO:0001541"(ovarian follicle development)|rcsb pdb:7KZR|go:"GO:0003684"(damaged DNA binding)|rcsb pdb:7KZS|go:"GO:0005654"(nucleoplasm)|rcsb pdb:7KZT|rcsb pdb:7KZV|reactome:R-HSA-6783310|go:"GO:0005730"(nucleolus) psi-mi:"MI:0471"(mint) - - figure legend:ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:jVGeic2vn/qrZgro3IKXWhNteHo9606 intact-crc:749E121DBC443016|rigid:VUsCUWR++GF76Fc8mT3LpR/eMV0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:Q9H4K1 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-740128|uniprotkb:Q6ICD0|uniprotkb:Q9Y413|ensembl:ENSP00000483356|uniprotkb:A0A087X0F7 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:ribc2_human(display_long)|uniprotkb:RIBC2(gene name)|psi-mi:RIBC2(display_short)|uniprotkb:C22orf11(gene name synonym) psi-mi:"MI:0231"(mammalian protein protein interaction trap) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677411|imex:IM-22977-350 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) ensembl:ENSG00000128408(gene)|ensembl:ENST00000614167(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR008805(RIB43A)|refseq:XP_005261581.1|refseq:NP_056468.3 psi-mi:"MI:0471"(mint) - - figure legend:ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/07/21 2019/11/14 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:rU6ggF8fZGGy7ICGFHxeMZQLkw49606 intact-crc:7E339AA568F950F8|rigid:jBn3FS21nDC+gzVuol8QDxilLn4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NP87 uniprotkb:P14079 intact:EBI-9675790|uniprotkb:Q86WQ9|uniprotkb:D3DVK4|uniprotkb:Q6P5X8|ensembl:ENSP00000242248 intact:EBI-9675698|uniprotkb:O56231 psi-mi:dpolm_human(display_long)|uniprotkb:POLM(gene name)|psi-mi:POLM(display_short)|uniprotkb:Terminal transferase(gene name synonym)|uniprotkb:polmu(gene name synonym) psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:"MI:0231"(mammalian protein protein interaction trap) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677416|imex:IM-22977-351 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271259.1|refseq:NP_001271260.1|refseq:NP_037416.1|rcsb pdb:6IPK|rcsb pdb:6IPL|rcsb pdb:6IPM|rcsb pdb:6IPN|rcsb pdb:6P1M|rcsb pdb:6P1N|rcsb pdb:6P1O|rcsb pdb:6P1P|rcsb pdb:6P1Q|rcsb pdb:6P1R|rcsb pdb:6P1S|rcsb pdb:6P1T|rcsb pdb:6P1U|rcsb pdb:6P1V|rcsb pdb:6P1W|rcsb pdb:6WIC|rcsb pdb:6WID|rcsb pdb:6WIE|rcsb pdb:7CO6|rcsb pdb:7CO8|rcsb pdb:7CO9|rcsb pdb:7COA|rcsb pdb:7COB|rcsb pdb:7COC|rcsb pdb:7COD|reactome:R-HSA-5693571|ensembl:ENSG00000122678(gene)|ensembl:ENST00000242248(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|interpro:IPR001357(BRCT)|interpro:IPR001726(DNA nucleotidylexotransferase)|interpro:IPR002054(DNA-directed DNA polymerase, family X)|interpro:IPR010996(DNA-directed DNA polymerase, family X, beta-like, N-terminal)|interpro:IPR018944|interpro:IPR019843|interpro:IPR022312|interpro:IPR027249|interpro:IPR027421|interpro:IPR028207|interpro:IPR029398|interpro:IPR036420|interpro:IPR037160|interpro:IPR043519|rcsb pdb:2DUN|rcsb pdb:2HTF|rcsb pdb:4LZD|rcsb pdb:4LZG|rcsb pdb:4M04|rcsb pdb:4M0A|rcsb pdb:4YCX|rcsb pdb:4YD1|rcsb pdb:4YD2|rcsb pdb:5TWP|rcsb pdb:5TWQ|rcsb pdb:5TWR|rcsb pdb:5TWS|rcsb pdb:5TXX|rcsb pdb:5TXZ|rcsb pdb:5TYB|rcsb pdb:5TYC|rcsb pdb:5TYD|rcsb pdb:5TYE|rcsb pdb:5TYF|rcsb pdb:5TYG|rcsb pdb:5TYU|rcsb pdb:5TYV|rcsb pdb:5TYW|rcsb pdb:5TYX|rcsb pdb:5TYY|rcsb pdb:5TYZ|rcsb pdb:5VZ7|rcsb pdb:5VZ8|rcsb pdb:5VZ9|rcsb pdb:5VZA|rcsb pdb:5VZB|rcsb pdb:5VZC|rcsb pdb:5VZD|rcsb pdb:5VZE|rcsb pdb:5VZF|rcsb pdb:5VZG|rcsb pdb:5VZH|rcsb pdb:5VZI|rcsb pdb:5W4F|rcsb pdb:5ZLC|rcsb pdb:6AEC|rcsb pdb:6AEH|rcsb pdb:6AK5|rcsb pdb:6AK6|rcsb pdb:6AK8|rcsb pdb:6AK9|rcsb pdb:6AKH|rcsb pdb:6IPD|rcsb pdb:6IPE|rcsb pdb:6IPF|rcsb pdb:6IPG|rcsb pdb:6IPH|rcsb pdb:6IPI|rcsb pdb:6IPJ interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) psi-mi:"MI:0471"(mint) - - figure legend:ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/07/21 2014/11/02 rogid:PjYb9sk0XvVaJwJ3JdGQY4IvenE9606 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 intact-crc:148A6780DE0B7B42|rigid:nZA7YVznR+9uH7ecylRKeQjBF8k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:P19013 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-2371606|uniprotkb:Q6GTR8|uniprotkb:Q96LA7|uniprotkb:Q9BTL1|intact:EBI-22121113|uniprotkb:B4DRS2|uniprotkb:F8VS64|intact:EBI-22010019|intact:EBI-28973341|ensembl:ENSP00000448220 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:k2c4_human(display_long)|uniprotkb:KRT4(gene name)|psi-mi:KRT4(display_short)|uniprotkb:CYK4(gene name synonym)|uniprotkb:Cytokeratin-4(gene name synonym)|uniprotkb:Keratin-4(gene name synonym)|uniprotkb:Type-II keratin Kb4(gene name synonym) psi-mi:"MI:0231"(mammalian protein protein interaction trap) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677421|imex:IM-22977-352 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) ensembl:ENSP00000448220|refseq:NP_002263.3|ensembl:ENSG00000170477(gene)|ensembl:ENST00000551956(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0009986"(cell surface)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0045095"(keratin filament)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|mint:P19013|reactome:R-HSA-6805567|reactome:R-HSA-6809371 psi-mi:"MI:0471"(mint) - - figure legend:ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/07/21 2020/03/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:WBLRjdlqvNYbC7R2ZSNON6QLcOU9606 intact-crc:F292ACD734B9E48E|rigid:Wnd+0bdcXFGiZEIPOUvcc1+px8U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:P05787 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-297852|uniprotkb:Q14099|uniprotkb:Q14716|uniprotkb:Q14717|uniprotkb:Q53GJ0|uniprotkb:Q6DHW5|uniprotkb:Q6GMY0|uniprotkb:Q6P4C7|uniprotkb:Q96J60|ensembl:ENSP00000293308|ensembl:ENSP00000447402|ensembl:ENSP00000447566|uniprotkb:A8K4H3|uniprotkb:B0AZN5|uniprotkb:F8VXB4 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:k2c8_human(display_long)|uniprotkb:Keratin-8(gene name synonym)|uniprotkb:KRT8(gene name)|psi-mi:KRT8(display_short)|uniprotkb:CYK8(gene name synonym)|uniprotkb:Cytokeratin-8(gene name synonym)|uniprotkb:Type-II keratin Kb8(gene name synonym) psi-mi:"MI:0231"(mammalian protein protein interaction trap) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677426|imex:IM-22977-353 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_001243222.1|ensembl:ENSG00000170421(gene)|ensembl:ENST00000293308(transcript)|ensembl:ENST00000546897(transcript)|ensembl:ENST00000552551(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005911"(cell-cell junction)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030018"(Z disc)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045095"(keratin filament)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051599"(response to hydrostatic pressure)|go:"GO:0051707"(response to other organism)|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097284"(hepatocyte apoptotic process)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|mint:P05787|reactome:R-HSA-6805567|reactome:R-HSA-6809371|refseq:NP_002264.1|dip:DIP-424N psi-mi:"MI:0471"(mint) - - figure legend:ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:zyV8eOjx426ehjJYK4jsizORUws9606 intact-crc:527B6C7183443017|rigid:x7czc5DkQYDo3LHUx9TWiA9EhDY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:Q8IZQ1 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-1569256|uniprotkb:Q4W5K5|uniprotkb:Q6P0Q5|uniprotkb:Q8N1T2|uniprotkb:Q8NAV6|uniprotkb:Q96BS7|uniprotkb:Q96D33|uniprotkb:Q96N85|uniprotkb:Q9Y2J7|ensembl:ENSP00000295888 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:wdfy3_human(display_long)|uniprotkb:Autophagy-linked FYVE protein(gene name synonym)|uniprotkb:WDFY3(gene name)|psi-mi:WDFY3(display_short)|uniprotkb:KIAA0993(gene name synonym) psi-mi:"MI:0231"(mammalian protein protein interaction trap) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677406|imex:IM-22977-349 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_055806.2|refseq:XP_011530065.1|refseq:XP_011530067.1|ensembl:ENSG00000163625(gene)|ensembl:ENST00000295888(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016605"(PML body)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035973"(aggrephagy)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR019775|interpro:IPR023362|interpro:IPR036322|interpro:IPR036372|mint:Q8IZQ1|rcsb pdb:3WIM|rcsb pdb:6W9N psi-mi:"MI:0471"(mint) - - figure legend:ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:yVIfhD/TU9JhrQR8WCChT4Jpi8c9606 intact-crc:742C144576C60153|rigid:oCtNq/MukZ+J4BT1dPOIPMFLnno false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:P19012 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym) psi-mi:"MI:0231"(mammalian protein protein interaction trap) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677431|imex:IM-22977-354 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371 psi-mi:"MI:0471"(mint) - - figure legend:ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606 intact-crc:07AC06E3BBA261CB|rigid:RR3ow1wldjtVSxYngkmxlWNhEyM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29474 uniprotkb:P14079 intact:EBI-1391623|uniprotkb:A0S0A7|uniprotkb:E9PFR2|uniprotkb:Q13662|uniprotkb:Q14251|uniprotkb:Q14434|uniprotkb:Q6GSL5|uniprotkb:A8KA63|uniprotkb:B2RCQ1|uniprotkb:Q548C1|uniprotkb:Q9UDC6|uniprotkb:A0S0A8|ensembl:ENSP00000297494 intact:EBI-9675698|uniprotkb:O56231 psi-mi:nos3_human(display_long)|uniprotkb:Endothelial NOS(gene name synonym)|uniprotkb:EC-NOS(gene name synonym)|uniprotkb:NOS type III(gene name synonym)|uniprotkb:Constitutive NOS(gene name synonym)|uniprotkb:NOS3(gene name)|psi-mi:NOS3(display_short) psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:"MI:0231"(mammalian protein protein interaction trap) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677436|imex:IM-22977-355 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000594.2|refseq:NP_001153581.1|refseq:NP_001153582.1|refseq:NP_001153583.1|refseq:XP_016867721.1|dip:DIP-38479N|ensembl:ENSG00000164867(gene)|go:"GO:0034405"(response to fluid shear stress)|go:"GO:0034617"(tetrahydrobiopterin binding)|go:"GO:0034618"(arginine binding)|go:"GO:0042311"(vasodilation)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050661"(NADP binding)|go:"GO:0070168"(negative regulation of biomineral tissue development)|go:"GO:0097746"(blood vessel diameter maintenance)|ensembl:ENST00000297494(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003100"(regulation of systemic arterial blood pressure by endothelin)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003184"(pulmonary valve morphogenesis)|go:"GO:0003203"(endocardial cushion morphogenesis)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004517"(nitric-oxide synthase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006527"(arginine catabolic process)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007263"(nitric oxide mediated signal transduction)|interpro:IPR001094(Flavodoxin-like)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR004030(Nitric oxide synthase, oxygenase region)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR012144(Nitric-oxide synthase)|interpro:IPR017927|interpro:IPR017938|interpro:IPR023173|interpro:IPR029039|interpro:IPR036119|interpro:IPR039261|mint:P29474|rcsb pdb:1M9J|rcsb pdb:1M9K|rcsb pdb:1M9M|rcsb pdb:1M9Q|rcsb pdb:1M9R|rcsb pdb:1NIW|rcsb pdb:2LL7|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0009725"(response to hormone)|go:"GO:0010181"(FMN binding)|go:"GO:0010544"(negative regulation of platelet activation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014740"(negative regulation of muscle hyperplasia)|go:"GO:0014806"(smooth muscle hyperplasia)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0020037"(heme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031284"(positive regulation of guanylate cyclase activity)|go:"GO:0031644"(regulation of nervous system process)|go:"GO:0032496"(response to lipopolysaccharide)|rcsb pdb:2MG5|rcsb pdb:2N8J|rcsb pdb:3EAH|rcsb pdb:3NOS|rcsb pdb:4D1O|rcsb pdb:4D1P|rcsb pdb:5UO8|rcsb pdb:5UO9|rcsb pdb:5UOA|rcsb pdb:5UOB|rcsb pdb:5UOC|rcsb pdb:5VVB|rcsb pdb:5VVC|rcsb pdb:5VVD|rcsb pdb:5XOF|rcsb pdb:6AV6|rcsb pdb:6AV7|rcsb pdb:6CIE|rcsb pdb:6CIF|rcsb pdb:6NH1|rcsb pdb:6NH2|rcsb pdb:6NH3|rcsb pdb:6NH4|rcsb pdb:6NH5|rcsb pdb:6NH6|rcsb pdb:6NH7|rcsb pdb:6NH8|rcsb pdb:6NHF|rcsb pdb:6POU|rcsb pdb:6POV|rcsb pdb:6POW|rcsb pdb:6POX|rcsb pdb:6POY|rcsb pdb:6POZ|rcsb pdb:6PP0|rcsb pdb:6PP1|rcsb pdb:6PP2|rcsb pdb:6PP3|rcsb pdb:6PP4|reactome:R-HSA-1222556|reactome:R-HSA-1474151|reactome:R-HSA-203615|reactome:R-HSA-203641|reactome:R-HSA-203754|reactome:R-HSA-392154|reactome:R-HSA-5218920|reactome:R-HSA-9009391 interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) psi-mi:"MI:0471"(mint) - - figure legend:ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/07/21 2018/04/06 rogid:FIvVY2y5ltfs8KVWaMEHCEt2pMk9606 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 intact-crc:FED6F8720548E57A|rigid:EjPL/4tW1FuddaOPDoXBHt3D6NE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:P82932 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-716172|uniprotkb:Q96Q64|uniprotkb:Q9BSK8|uniprotkb:Q9BW89|uniprotkb:B2R573|ensembl:ENSP00000382250 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:rt06_human(display_long)|uniprotkb:MRPS6(gene name)|psi-mi:MRPS6(display_short)|uniprotkb:C21orf101(gene name synonym)|uniprotkb:RPMS6(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein bS6m(gene name synonym) psi-mi:"MI:0231"(mammalian protein protein interaction trap) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677456|imex:IM-22977-359 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_115865.1|ensembl:ENSG00000243927(gene)|ensembl:ENST00000399312(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR000529(Ribosomal protein S6)|interpro:IPR014717(Translation elongation factor EF1B/ribosomal protein S6)|interpro:IPR035980|mint:P82932|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZSA|rcsb pdb:6ZS9|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 psi-mi:"MI:0471"(mint) - - figure legend:ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:mMPTr45GZxT1pj2RBZvvG6TrQmo9606 intact-crc:3328D01D3348A37F|rigid:i3xXdNaXW0JVBwMoWJJckFbZ+IQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:Q969H6 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-366525|uniprotkb:Q53FS5|uniprotkb:Q9Y2Q6|uniprotkb:A6NL80|ensembl:ENSP00000350098 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:pop5_human(display_long)|uniprotkb:POP5(gene name)|psi-mi:POP5(display_short)|uniprotkb:AD-008(orf name)|uniprotkb:HSPC004(orf name)|uniprotkb:x0003(orf name) psi-mi:"MI:0231"(mammalian protein protein interaction trap) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677441|imex:IM-22977-356 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_057002.2|refseq:NP_937845.1|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|interpro:IPR002759(Ribonuclease P-related)|interpro:IPR016819(Ribonuclease P/MRP protein, subunit Pop5)|interpro:IPR038085|rcsb pdb:6AHR|rcsb pdb:6AHU|reactome:R-HSA-6784531|ensembl:ENSG00000167272(gene)|ensembl:ENST00000357500(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0005730"(nucleolus) psi-mi:"MI:0471"(mint) - - figure legend:ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:WYNesu92ICtpEM2lwO63c6hjcMY9606 intact-crc:86C1EBCEF9EB596B|rigid:7kmKU2Wq9Vx9Pjq7tIQ45iPlo3g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q33E94 uniprotkb:P14079 intact:EBI-9675925|uniprotkb:Q33DW7|uniprotkb:Q8SNA1|uniprotkb:Q33E95|uniprotkb:Q8NDF9|uniprotkb:B2RDW4|uniprotkb:Q96S80|uniprotkb:Q6YM53|uniprotkb:A8K5Y0|uniprotkb:Q8NC78|uniprotkb:Q33DW6|uniprotkb:Q9BXI0|uniprotkb:Q8MHQ1|ensembl:ENSP00000376585 intact:EBI-9675698|uniprotkb:O56231 psi-mi:rfx4_human(display_long)|uniprotkb:RFX4(gene name)|psi-mi:RFX4(display_short)|uniprotkb:Regulatory factor X 4(gene name synonym)|uniprotkb:Testis development protein NYD-SP10(gene name synonym) psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:"MI:0231"(mammalian protein protein interaction trap) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677446|imex:IM-22977-357 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001193620.1|refseq:NP_115880.2|refseq:NP_998759.1|ensembl:ENSG00000111783(gene)|ensembl:ENST00000392842(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0021537"(telencephalon development)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060271"(cilium assembly)|go:"GO:0070613"(regulation of protein processing)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003150(DNA-binding RFX)|interpro:IPR036388|interpro:IPR036390|interpro:IPR039779 interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) psi-mi:"MI:0471"(mint) - - figure legend:ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/07/21 2014/11/02 rogid:O/qU4dSVZOwdQyCzqRqgouHNd6s9606 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 intact-crc:A450F31688F381F5|rigid:03tv8gQUXP/mF/ijK4sarQnvvao false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:Q9GZT8 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-740897|uniprotkb:Q9H2D2|uniprotkb:Q9HC18|uniprotkb:Q6X735|uniprotkb:Q53TX4|ensembl:ENSP00000386394|ensembl:ENSP00000387315|ensembl:ENSP00000498853 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:nif3l_human(display_long)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein(gene name synonym)|uniprotkb:MDS015(orf name)|uniprotkb:My018(orf name)|uniprotkb:NIF3L1(gene name)|psi-mi:NIF3L1(display_short)|uniprotkb:ALS2CR1(gene name synonym) psi-mi:"MI:0231"(mammalian protein protein interaction trap) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677451|imex:IM-22977-358 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_001129511.1|refseq:NP_001135827.1|refseq:NP_068596.2|refseq:XP_011509887.1|refseq:XP_011509884.1|refseq:XP_011509885.1|refseq:XP_011509886.1|refseq:NP_001135828.1|refseq:XP_005246799.1|refseq:XP_016860119.1|ensembl:ENSG00000196290(gene)|ensembl:ENST00000409020(transcript)|ensembl:ENST00000409357(transcript)|ensembl:ENST00000651500(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1903507"(negative regulation of nucleic acid-templated transcription)|interpro:IPR002678(NGG1p interacting factor 3, NIF3)|interpro:IPR017222(Uncharacterised conserved protein UCP037490, NIF3, eukaryota)|interpro:IPR036069|mint:Q9GZT8 psi-mi:"MI:0471"(mint) - - figure legend:ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:Vvyb7CJpcwGtGAVKT2Zoqycr2yQ9606 intact-crc:23A821FB90216EC5|rigid:x17gWkhywLJG4lBfe0ESvGuhKis false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:Q8N883 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-9675993|uniprotkb:Q9BSN8|uniprotkb:Q8TCF4|uniprotkb:Q494T8|ensembl:ENSP00000270649 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:zn614_human(display_long)|uniprotkb:ZNF614(gene name)|psi-mi:ZNF614(display_short) psi-mi:"MI:0231"(mammalian protein protein interaction trap) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677461|imex:IM-22977-360 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_079316.2|ensembl:ENSG00000142556(gene)|ensembl:ENST00000270649(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436 psi-mi:"MI:0471"(mint) - - figure legend:ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:DTfWPcCHy/ZIwvALRCnGC6SMX749606 intact-crc:3FC92616BBDC7A5D|rigid:Hr2UBhwM50pqrX2T12B5CslJQTc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:Q9BY27 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-742953|ensembl:ENSP00000248879|uniprotkb:Q9BW33|uniprotkb:A8K1N7|uniprotkb:D3DX29|uniprotkb:B3KMC0 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:dgc6l_human(display_long)|uniprotkb:DiGeorge syndrome critical region 6-like protein(gene name synonym)|uniprotkb:DGCR6L(gene name)|psi-mi:DGCR6L(display_short) psi-mi:"MI:0231"(mammalian protein protein interaction trap) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677481|imex:IM-22977-364 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) go:"GO:0005634"(nucleus)|interpro:IPR010849(DiGeorge syndrome critical 6)|ensembl:ENSG00000128185(gene)|ensembl:ENST00000248879(transcript)|refseq:NP_150282.2 psi-mi:"MI:0471"(mint) - - figure legend:ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:kgKOLihCtc75qwW051IZsGLspI09606 intact-crc:EE2AF173E70411E1|rigid:7ojyAekopTtJ6YR6b7+YYowkRyw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:Q53HC0 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-719994|uniprotkb:Q9H697|uniprotkb:B3KNQ0|ensembl:ENSP00000238156|ensembl:ENSP00000488830 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:ccd92_human(display_long)|uniprotkb:Limkain beta-2(gene name synonym)|uniprotkb:CCDC92(gene name)|psi-mi:CCDC92(display_short) psi-mi:"MI:0231"(mammalian protein protein interaction trap) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677471|imex:IM-22977-362 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_079416.1|ensembl:ENSG00000119242(gene)|ensembl:ENSG00000275035(gene)|ensembl:ENST00000238156(transcript)|ensembl:ENST00000632401(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR033224|interpro:IPR039496|interpro:IPR040370|mint:Q53HC0|refseq:NP_001291886.1|refseq:NP_001291887.1|refseq:NP_001291888.1|refseq:NP_001291889.1|refseq:NP_001291890.1|refseq:XP_005253681.1|refseq:XP_016875473.1 psi-mi:"MI:0471"(mint) - - figure legend:ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:Iu/FzTqEpzn8N5WUTt1OwoKWxyc9606 intact-crc:1C2709875F0911D4|rigid:6KI5X6DXx27+SUDj5xhWPc5/sKo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:Q96MT8 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-741977|uniprotkb:Q96CR0|uniprotkb:Q9H8F5|uniprotkb:Q9H8N0|uniprotkb:D3DND8|uniprotkb:D3DND9|uniprotkb:D3DNE0|ensembl:ENSP00000426129|ensembl:ENSP00000475903|ensembl:ENSP00000502085|ensembl:ENSP00000506896 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:cep63_human(display_long)|uniprotkb:CEP63(gene name)|psi-mi:CEP63(display_short) psi-mi:"MI:0231"(mammalian protein protein interaction trap) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677476|imex:IM-22977-363 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) go:"GO:0000922"(spindle pole)|go:"GO:0005829"(cytosol)|refseq:NP_001035842.1|refseq:NP_001035843.1|refseq:NP_001035859.1|refseq:NP_079456.2|ensembl:ENSG00000182923(gene)|ensembl:ENST00000513612(transcript)|ensembl:ENST00000606977(transcript)|ensembl:ENST00000675561(transcript)|ensembl:ENST00000683596(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005814"(centriole)|go:"GO:0005813"(centrosome)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|interpro:IPR029608|interpro:IPR031470|mint:Q96MT8|rcsb pdb:6CSU|rcsb pdb:6CSV|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|go:"GO:0007099"(centriole replication)|refseq:XP_011511496.1|refseq:XP_005247854.1|refseq:XP_006713823.1|refseq:XP_016862743.1|refseq:XP_016862744.1|refseq:XP_016862745.1|refseq:XP_016862751.1|refseq:XP_016862752.1|refseq:XP_016862753.1|refseq:XP_016862755.1|refseq:XP_016862756.1|dip:DIP-36374N psi-mi:"MI:0471"(mint) - - figure legend:ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:/WPfint+sTGNCYCH9XG5rPYSOm09606 intact-crc:F0EAAB311B626D87|rigid:m33nyxKJYvhOb1y+xLbuKM7yhcY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:Q6ZVK8 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-740486|intact:EBI-954151|ensembl:ENSP00000480722|uniprotkb:Q9H687|uniprotkb:Q8IZ75 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:nud18_human(display_long)|uniprotkb:NUDT18(gene name)|psi-mi:NUDT18(display_short)|uniprotkb:2-hydroxy-dADP phosphatase(gene name synonym)|uniprotkb:7,8-dihydro-8-oxoguanine phosphatase(gene name synonym)|uniprotkb:MTH3(gene name synonym)|uniprotkb:MutT homolog 3(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 18(gene name synonym) psi-mi:"MI:0231"(mammalian protein protein interaction trap) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677466|imex:IM-22977-361 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_079091.3|ensembl:ENST00000611621(transcript)|ensembl:ENSG00000275074(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0044715"(8-oxo-dGDP phosphatase activity)|go:"GO:0044716"(8-oxo-GDP phosphatase activity)|go:"GO:0044717"(8-hydroxy-dADP phosphatase activity)|go:"GO:0046057"(dADP catabolic process)|go:"GO:0046067"(dGDP catabolic process)|go:"GO:0046712"(GDP catabolic process)|go:"GO:0055086"(nucleobase-containing small molecule metabolic process)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR020476|interpro:IPR042970|rcsb pdb:3GG6|rcsb pdb:4HVY|reactome:R-HSA-2393930 psi-mi:"MI:0471"(mint) - - figure legend:ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:IBrXB2HhvhcyxMTQ0Xs5hGiimzA9606 intact-crc:537A7E2563CF0182|rigid:iqmd6OEDYiB8xhFLBLx7NvQuFwc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03363 uniprotkb:O14770 intact:EBI-9676133 intact:EBI-2804934|uniprotkb:Q96KI5|uniprotkb:Q9NRS3|uniprotkb:Q9NRS1|uniprotkb:Q9NRS2|uniprotkb:Q96KI4|ensembl:ENSP00000453793|uniprotkb:A6NJI5|uniprotkb:A8MWD5|uniprotkb:B3KP98|uniprotkb:B3KPQ6|uniprotkb:Q96DI2 psi-mi:pol_htlv2(display_long)|uniprotkb:gag-pro-pol(gene name)|psi-mi:gag-pro-pol(display_short)|uniprotkb:Pr160Gag-Pro-Pol(gene name synonym) psi-mi:meis2_human(display_long)|uniprotkb:MRG1(gene name synonym)|uniprotkb:Meis1-related protein 1(gene name synonym)|uniprotkb:MEIS2(gene name)|psi-mi:MEIS2(display_short) psi-mi:"MI:0231"(mammalian protein protein interaction trap) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677506|imex:IM-22977-369 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001037(Integrase, C-terminal, retroviral)|interpro:IPR001584(Integrase, catalytic core)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR001995(Peptidase A2A, retrovirus, catalytic)|interpro:IPR002156(Ribonuclease H)|interpro:IPR003139(Delta-retroviral matrix, N-terminal)|interpro:IPR003308(Integrase, N-terminal zinc-binding domain)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR018061|interpro:IPR021109|rcsb pdb:1JVR|refseq:NP_041003.3|interpro:IPR036397|interpro:IPR036862|interpro:IPR036875|rcsb pdb:6QBT|rcsb pdb:6QBV|rcsb pdb:6QBW|interpro:IPR043502|interpro:IPR043128|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0003964"(RNA-directed DNA polymerase activity)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015074"(DNA integration)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0044826"(viral genome integration into host DNA)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0075713"(establishment of integrated proviral latency) ensembl:ENSG00000134138(gene)|ensembl:ENST00000561208(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008542"(visual learning)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0031016"(pancreas development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070848"(response to growth factor)|go:"GO:0110024"(positive regulation of cardiac muscle myoblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|mint:O14770|rcsb pdb:3K2A|rcsb pdb:4XRM|rcsb pdb:5BNG|rcsb pdb:5EG0|refseq:NP_001207411.1|refseq:NP_733774.1|refseq:NP_733775.1|refseq:NP_733776.1|refseq:NP_733777.1|refseq:NP_002390.1|refseq:NP_758526.1|refseq:NP_758527.1|ensembl:ENST00000314177|ensembl:ENSP00000326296|ensembl:ENST00000338564|ensembl:ENSP00000341400|ensembl:ENST00000340545|ensembl:ENSP00000339549|ensembl:ENST00000397620|ensembl:ENSP00000380745|ensembl:ENST00000397624|ensembl:ENSP00000380749|ensembl:ENST00000424352|ensembl:ENSP00000404185|ensembl:ENST00000557796|ensembl:ENSP00000452693|ensembl:ENST00000559085|ensembl:ENSP00000453390|ensembl:ENST00000559561|ensembl:ENSP00000453497|ensembl:ENSP00000453793|refseq:XP_016877694.1|dip:DIP-61027N psi-mi:"MI:0471"(mint) - - figure legend:ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/07/21 2014/10/16 rogid:3FlrPwlig4Db1uLRMaZz+1EKx7Q11909 rogid:dzZaH/NCkNWqc4N6ZVa+i5Knqrg9606 intact-crc:FA080AB92C1432C1|rigid:BmVi4jUnfGRwXUgrTPOQZ6IQu1o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03383 uniprotkb:O43513 intact:EBI-9676086|uniprotkb:P03382 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 psi-mi:env_htlv2(display_long)|uniprotkb:env(gene name)|psi-mi:env(display_short)|uniprotkb:Env polyprotein(gene name synonym) psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:"MI:0231"(mammalian protein protein interaction trap) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677501|imex:IM-22977-368 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018154|refseq:NP_041006.1|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0055036"(virion membrane)|go:"GO:0019031"(viral envelope) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM psi-mi:"MI:0471"(mint) - - figure legend:ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/07/21 2014/10/16 rogid:iX64ZtD99Z1yVZ7DOWVSdgLJaTY11909 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 intact-crc:6E9CC9F1334E5D97|rigid:dKvxa1OWsn5X9j4gdjbP/hruQ98 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:Q92546 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-2823702|uniprotkb:Q5TCV5|ensembl:ENSP00000367318 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:rgp1_human(display_long)|uniprotkb:RGP1(gene name)|psi-mi:RGP1(display_short)|uniprotkb:Retrograde Golgi transport protein RGP1 homolog(gene name synonym)|uniprotkb:KIAA0258(gene name synonym) psi-mi:"MI:0231"(mammalian protein protein interaction trap) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677496|imex:IM-22977-367 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_001073965.2|ensembl:ENSG00000107185(gene)|ensembl:ENST00000378078(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034066"(Ric1-Rgp1 guanyl-nucleotide exchange factor complex)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:1903363"(negative regulation of cellular protein catabolic process)|interpro:IPR014848(Rgp1)|reactome:R-HSA-6811438|reactome:R-HSA-6811440|reactome:R-HSA-8876198 psi-mi:"MI:0471"(mint) - - figure legend:ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:1clc9Psb0xKDstfEkTk/dxivDfM9606 intact-crc:FB6EF702E74624DF|rigid:iYxKJA+9erFJAczH6Mw/xQcZmE4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:P78560 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-520375|uniprotkb:B7Z2Q5|ensembl:ENSP00000327647|ensembl:ENSP00000439068 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:cradd_human(display_long)|uniprotkb:Caspase and RIP adapter with death domain(gene name synonym)|uniprotkb:RIP-associated protein with a death domain(gene name synonym)|uniprotkb:CRADD(gene name)|psi-mi:CRADD(display_short)|uniprotkb:RAIDD(gene name synonym) psi-mi:"MI:0231"(mammalian protein protein interaction trap) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677486|imex:IM-22977-365 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_003796.1|refseq:NP_001307029.1|refseq:NP_001307030.1|refseq:NP_001307028.1|refseq:XP_016875633.1|ensembl:ENSG00000169372(gene)|ensembl:ENST00000332896(transcript)|ensembl:ENST00000542893(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005829"(cytosol)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0070513"(death domain binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000488(Death)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR011029(DEATH-like)|interpro:IPR037926|interpro:IPR037939|interpro:IPR042148|mint:P78560|rcsb pdb:2O71|rcsb pdb:2OF5|rcsb pdb:3CRD|reactome:R-HSA-6803207|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm) psi-mi:"MI:0471"(mint) - - figure legend:ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:koYvv+L+23G4lMEFIFmYYBNaNkk9606 intact-crc:1DAB43C408F3529B|rigid:0jPLmZ5kahwMuAt4JZAfGjEdWEs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14079 uniprotkb:Q969F0 intact:EBI-9675698|uniprotkb:O56231 intact:EBI-743099|ensembl:ENSP00000359375 psi-mi:tax_htl1c(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Protein X-LOR(gene name synonym)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-1(gene name synonym) psi-mi:fate1_human(display_long)|uniprotkb:Tumor antigen BJ-HCC-2(gene name synonym)|uniprotkb:Cancer/testis antigen 43(gene name synonym)|uniprotkb:FATE1(gene name)|psi-mi:FATE1(display_short)|uniprotkb:FATE(gene name synonym) psi-mi:"MI:0231"(mammalian protein protein interaction trap) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677491|imex:IM-22977-366 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|rcsb pdb:1AO7|rcsb pdb:1HHK|rcsb pdb:1IM3|rcsb pdb:2AV1|rcsb pdb:2AV7|refseq:NP_057864.1|rcsb pdb:1BD2|rcsb pdb:6UZ1|rcsb pdb:5IRO|go:"GO:0003677"(DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071222"(cellular response to lipopolysaccharide) refseq:NP_149076.1|ensembl:ENSG00000147378(gene)|ensembl:ENST00000370350(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|interpro:IPR039153|interpro:IPR039433|mint:Q969F0 psi-mi:"MI:0471"(mint) - - figure legend:ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/07/21 2014/11/02 rogid:ofA+D+rfw1h6YniybfOigpbkFgI11927 rogid:Nm1N6lO92MHr5rIKC007oouF5RE9606 intact-crc:9D7165D8C4E8C3C3|rigid:nKr2+UEHSKF/5jctkdLdn5Zb5TI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:O43186 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-748171|uniprotkb:Q0QD45|ensembl:ENSP00000221996|ensembl:ENSP00000445565 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:crx_human(display_long)|uniprotkb:CRX(gene name)|psi-mi:CRX(display_short)|uniprotkb:CORD2(gene name synonym) psi-mi:"MI:0231"(mammalian protein protein interaction trap) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677526|imex:IM-22977-373 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_000545.1|ensembl:ENSG00000105392(gene)|ensembl:ENST00000221996(transcript)|ensembl:ENST00000539067(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050896"(response to stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970 psi-mi:"MI:0471"(mint) - - figure legend:ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:v/bkO/0iLzq1Q2HtieWQQ40RF9M9606 intact-crc:FFB567EE641B86FA|rigid:CbXhSStMGDnr4S1rdtD3hZH+NyI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:Q9Y2D8 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym) psi-mi:"MI:0231"(mammalian protein protein interaction trap) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677521|imex:IM-22977-372 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8 psi-mi:"MI:0471"(mint) - - figure legend:ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606 intact-crc:A889CC029C5BACDE|rigid:4yfIE9G9j3f1FHFEjsZvM0d9kys false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q85601 uniprotkb:Q9GZT8 intact:EBI-9676175 intact:EBI-740897|uniprotkb:Q9H2D2|uniprotkb:Q9HC18|uniprotkb:Q6X735|uniprotkb:Q53TX4|ensembl:ENSP00000386394|ensembl:ENSP00000387315|ensembl:ENSP00000498853 psi-mi:rex_htlv2(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-2(gene name synonym) psi-mi:nif3l_human(display_long)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein(gene name synonym)|uniprotkb:MDS015(orf name)|uniprotkb:My018(orf name)|uniprotkb:NIF3L1(gene name)|psi-mi:NIF3L1(display_short)|uniprotkb:ALS2CR1(gene name synonym) psi-mi:"MI:0231"(mammalian protein protein interaction trap) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677516|imex:IM-22977-371 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041004.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) refseq:NP_001129511.1|refseq:NP_001135827.1|refseq:NP_068596.2|refseq:XP_011509887.1|refseq:XP_011509884.1|refseq:XP_011509885.1|refseq:XP_011509886.1|refseq:NP_001135828.1|refseq:XP_005246799.1|refseq:XP_016860119.1|ensembl:ENSG00000196290(gene)|ensembl:ENST00000409020(transcript)|ensembl:ENST00000409357(transcript)|ensembl:ENST00000651500(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1903507"(negative regulation of nucleic acid-templated transcription)|interpro:IPR002678(NGG1p interacting factor 3, NIF3)|interpro:IPR017222(Uncharacterised conserved protein UCP037490, NIF3, eukaryota)|interpro:IPR036069|mint:Q9GZT8 psi-mi:"MI:0471"(mint) - - figure legend:ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/07/21 2014/10/16 rogid:JALmnTn2BuPjeDXSyA8raxDgM0411909 rogid:Vvyb7CJpcwGtGAVKT2Zoqycr2yQ9606 intact-crc:5F96E0E9F123A429|rigid:Eeg/kPnMrNcgtF3nawxkSuKXhr0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q85601 uniprotkb:Q96FJ2 intact:EBI-9676175 intact:EBI-742371|uniprotkb:B2R5B4|ensembl:ENSP00000477310 psi-mi:rex_htlv2(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-2(gene name synonym) psi-mi:dyl2_human(display_long)|uniprotkb:DYNLL2(gene name)|psi-mi:DYNLL2(display_short)|uniprotkb:Dynein light chain LC8-type 2(gene name synonym)|uniprotkb:DLC2(gene name synonym)|uniprotkb:8 kDa dynein light chain b(gene name synonym) psi-mi:"MI:0231"(mammalian protein protein interaction trap) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677511|imex:IM-22977-370 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_041004.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) go:"GO:0005813"(centrosome)|refseq:NP_542408.1|ensembl:ENSG00000264364(gene)|ensembl:ENST00000579991(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0007017"(microtubule-based process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0030286"(dynein complex)|go:"GO:0031475"(myosin V complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097542"(ciliary tip)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:Q96FJ2|rcsb pdb:2XQQ|rcsb pdb:3P8M|rcsb pdb:4D07|reactome:R-HSA-139910|reactome:R-HSA-141444|reactome:R-HSA-1632852|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-5620924|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025 psi-mi:"MI:0471"(mint) - - figure legend:ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/07/21 2014/10/16 rogid:JALmnTn2BuPjeDXSyA8raxDgM0411909 rogid:4RFpJF40RBja5mOvt/aCv3miiDU9606 intact-crc:6BC85156E4D9535C|rigid:0i6piXIDT5hPVHTIqdAcNyclymc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:P82932 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-716172|uniprotkb:Q96Q64|uniprotkb:Q9BSK8|uniprotkb:Q9BW89|uniprotkb:B2R573|ensembl:ENSP00000382250 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:rt06_human(display_long)|uniprotkb:MRPS6(gene name)|psi-mi:MRPS6(display_short)|uniprotkb:C21orf101(gene name synonym)|uniprotkb:RPMS6(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein bS6m(gene name synonym) psi-mi:"MI:0231"(mammalian protein protein interaction trap) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677541|imex:IM-22977-376 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_115865.1|ensembl:ENSG00000243927(gene)|ensembl:ENST00000399312(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR000529(Ribosomal protein S6)|interpro:IPR014717(Translation elongation factor EF1B/ribosomal protein S6)|interpro:IPR035980|mint:P82932|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZSA|rcsb pdb:6ZS9|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 psi-mi:"MI:0471"(mint) - - figure legend:ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:mMPTr45GZxT1pj2RBZvvG6TrQmo9606 intact-crc:A9CC8C7C334A30A6|rigid:hCeLrXkOSuops84LJobStx/OcXA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:Q9NZD8 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-742688|uniprotkb:B4DW44|uniprotkb:Q6ZMB6|ensembl:ENSP00000204566|ensembl:ENSP00000404111 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:spg21_human(display_long)|uniprotkb:Spastic paraplegia 21 autosomal recessive Mast syndrome protein(gene name synonym)|uniprotkb:Acid cluster protein 33(gene name synonym)|uniprotkb:SPG21(gene name)|psi-mi:SPG21(display_short)|uniprotkb:ACP33(gene name synonym)|uniprotkb:BM-019(orf name)|uniprotkb:GL010(orf name)|uniprotkb:Spastic paraplegia 21 protein(gene name synonym) psi-mi:"MI:0231"(mammalian protein protein interaction trap) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677536|imex:IM-22977-375 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_001121361.1|refseq:NP_001121362.1|refseq:NP_057714.1|ensembl:ENSG00000090487(gene)|ensembl:ENST00000204566(transcript)|ensembl:ENST00000433215(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR026151|interpro:IPR029058|mint:Q9NZD8|refseq:XP_005254494.1|refseq:XP_016877786.1|refseq:XP_016877787.1 psi-mi:"MI:0471"(mint) - - figure legend:ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:MoKySBpEYFNm7Lox/HM5nnkmhkA9606 intact-crc:71E850951329D5BF|rigid:2R/jnnVOInc6+RMFMKYwJOOakKc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:Q6PEX3 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-3957672|ensembl:ENSP00000353742|uniprotkb:B0RZD3 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:kr261_human(display_long)|uniprotkb:KRTAP26-1(gene name)|psi-mi:KRTAP26-1(display_short)|uniprotkb:KAP26.1(gene name synonym) psi-mi:"MI:0231"(mammalian protein protein interaction trap) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677531|imex:IM-22977-374 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) ensembl:ENSG00000197683(gene)|ensembl:ENST00000360542(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|interpro:IPR007951(PMG)|reactome:R-HSA-6805567|refseq:NP_981950.1 psi-mi:"MI:0471"(mint) - - figure legend:ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:VKgQPRg2qO2FXQx0fQ/dd/5kMws9606 intact-crc:5606136A4A4D0E91|rigid:si8ReoMWQMPSvGPbjGA7CYOwLyY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:P35711 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-3505701|uniprotkb:Q86UK8|uniprotkb:Q8J017|uniprotkb:Q8J018|uniprotkb:Q8J019|uniprotkb:Q8J020|uniprotkb:Q8N1D9|uniprotkb:Q8N7E0|uniprotkb:Q8TEA4|uniprotkb:B7Z8V0|uniprotkb:F5H5B0|ensembl:ENSP00000398273 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:sox5_human(display_long)|uniprotkb:SOX5(gene name)|psi-mi:SOX5(display_short) psi-mi:"MI:0231"(mammalian protein protein interaction trap) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677546|imex:IM-22977-377 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_008871.3|refseq:NP_694534.1|refseq:NP_821078.1|refseq:NP_001248343.1|refseq:NP_001248344.1|ensembl:ENSG00000134532(gene)|ensembl:ENST00000451604(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001502"(cartilage condensation)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0045165"(cell fate commitment)|go:"GO:0051216"(cartilage development)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0061036"(positive regulation of cartilage development)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:2000741"(positive regulation of mesenchymal stem cell differentiation)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|mint:P35711|refseq:NP_001317714.1|refseq:XP_016875385.1 psi-mi:"MI:0471"(mint) - - figure legend:ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:YVl5zcnqafFgRvQt8B79kMtbz+g9606 intact-crc:1A04936C7987F2B3|rigid:DQz53+P9sHPbU/vTPfwDIijl15I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03410 uniprotkb:Q9BRK4 intact:EBI-9676218|uniprotkb:Q85602|uniprotkb:P03411 intact:EBI-741037|ensembl:ENSP00000359240|ensembl:ENSP00000359243|uniprotkb:Q8N3I0|uniprotkb:Q96J79|uniprotkb:Q96JL2|uniprotkb:B1AL14|uniprotkb:D3DR72 psi-mi:tax_htlv2(display_long)|uniprotkb:tax(gene name)|psi-mi:tax(display_short)|uniprotkb:Trans-activating transcriptional regulatory protein of HTLV-2(gene name synonym) psi-mi:lzts2_human(display_long)|uniprotkb:Protein LAPSER1(gene name synonym)|uniprotkb:LZTS2(gene name)|psi-mi:LZTS2(display_short)|uniprotkb:KIAA1813(gene name synonym)|uniprotkb:LAPSER1(gene name synonym) psi-mi:"MI:0231"(mammalian protein protein interaction trap) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11909(htlv-2)|taxid:11909(Human T-cell leukemia virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9677551|imex:IM-22977-378 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004120(HTLV Tat)|refseq:NP_041005.1|interpro:IPR036922|go:"GO:0003677"(DNA binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding) refseq:NP_115805.1|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:0031982"(vesicle)|go:"GO:0051013"(microtubule severing)|go:"GO:0051168"(nuclear export)|go:"GO:0051255"(spindle midzone assembly)|go:"GO:0060682"(primary ureteric bud growth)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR028597|mint:Q9BRK4|ensembl:ENSG00000107816(gene)|ensembl:ENST00000370220(transcript)|ensembl:ENST00000370223(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|refseq:XP_016872269.1|refseq:NP_001305028.1|refseq:NP_001305029.1|refseq:NP_001305030.1|refseq:XP_005270279.1 psi-mi:"MI:0471"(mint) - - figure legend:ST6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/07/21 2014/10/16 rogid:eMBFV5ZK+ZTHf+WxhRGg8OEcgB811909 rogid:OaMJmnmfm6JniKUJeyg7fS6zRcw9606 intact-crc:4CCD7E2C22137AAC|rigid:96c8F/VbsYsCoq7CtyIRoF8qkJc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C206 uniprotkb:Q96FJ2 intact:EBI-9675596|uniprotkb:O56230 intact:EBI-742371|uniprotkb:B2R5B4|ensembl:ENSP00000477310 psi-mi:rex_htl1c(display_long)|uniprotkb:Rev homolog(gene name synonym)|uniprotkb:Rex-1(gene name synonym)|uniprotkb:p27Rex(gene name synonym) psi-mi:dyl2_human(display_long)|uniprotkb:DYNLL2(gene name)|psi-mi:DYNLL2(display_short)|uniprotkb:Dynein light chain LC8-type 2(gene name synonym)|uniprotkb:DLC2(gene name synonym)|uniprotkb:8 kDa dynein light chain b(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Simonis et al. (2012) imex:IM-22977|pubmed:22458338 taxid:11927(htl1c)|taxid:11927("Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-9677584|imex:IM-22977-379 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1EXY|refseq:NP_057863.1|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport) go:"GO:0005813"(centrosome)|refseq:NP_542408.1|ensembl:ENSG00000264364(gene)|ensembl:ENST00000579991(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0007017"(microtubule-based process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0030286"(dynein complex)|go:"GO:0031475"(myosin V complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097542"(ciliary tip)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:Q96FJ2|rcsb pdb:2XQQ|rcsb pdb:3P8M|rcsb pdb:4D07|reactome:R-HSA-139910|reactome:R-HSA-141444|reactome:R-HSA-1632852|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-5620924|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|go:"GO:0044452"(obsolete nucleolar part)|go:"GO:0005737"(cytoplasm) go:"GO:0044452"(obsolete nucleolar part) - - figure legend:f6a|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2014/07/21 2014/11/02 rogid:Jg3y2XqUP/JBerfBYcxMesTuQFQ11927 rogid:4RFpJF40RBja5mOvt/aCv3miiDU9606 intact-crc:2645D776342C501B|rigid:Nh0EMng3CiDDBeEjvC43fAW+OyU false green fluorescent protein tag:?-? flag tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0707"(anti tag immunostaining)