#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P35555	uniprotkb:P55083	intact:EBI-2505934|ensembl:ENSP00000325527|uniprotkb:B2RUU0|uniprotkb:Q15972|uniprotkb:Q75N87|uniprotkb:D2JYH6	intact:EBI-2829794|uniprotkb:Q6P680|uniprotkb:A8KAJ1|uniprotkb:A8MVM2|uniprotkb:B4E317|ensembl:ENSP00000299610	psi-mi:fbn1_human(display_long)|uniprotkb:FBN1(gene name)|psi-mi:FBN1(display_short)|uniprotkb:FBN(gene name synonym)	psi-mi:mfap4_human(display_long)|uniprotkb:MFAP4(gene name)|psi-mi:MFAP4(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Kasamatsu et al. (2011)	pubmed:22355679|imex:IM-22574	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-9119527|imex:IM-22574-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000166147(gene)|ensembl:ENST00000316623(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001527"(microfibril)|go:"GO:0001656"(metanephros development)|go:"GO:0005178"(integrin binding)|go:"GO:0005179"(hormone activity)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0007507"(heart development)|go:"GO:0008201"(heparin binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030023"(extracellular matrix constituent conferring elasticity)|go:"GO:0031012"(extracellular matrix)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034199"(activation of protein kinase A activity)|go:"GO:0035582"(sequestering of BMP in extracellular matrix)|go:"GO:0035583"(sequestering of TGFbeta in extracellular matrix)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0048048"(embryonic eye morphogenesis)|go:"GO:0048050"(post-embryonic eye morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:2001205"(negative regulation of osteoclast development)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011398(Fibrillin)|interpro:IPR017878|interpro:IPR018097|interpro:IPR026823|interpro:IPR036773|interpro:IPR040872|mint:P35555|rcsb pdb:1APJ|rcsb pdb:1EMN|rcsb pdb:1EMO|rcsb pdb:1LMJ|rcsb pdb:1UZJ|rcsb pdb:1UZK|rcsb pdb:1UZP|rcsb pdb:1UZQ|rcsb pdb:2M74|rcsb pdb:2W86|rcsb pdb:5MS9|reactome:R-HSA-1474228|reactome:R-HSA-1566948|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-381426|reactome:R-HSA-8957275|refseq:NP_000129.3|dip:DIP-29985N	refseq:NP_001185624.1|refseq:NP_002395.1|ensembl:ENSG00000166482(gene)|ensembl:ENST00000299610(transcript)|go:"GO:0001527"(microfibril)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0003823"(antigen binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0007155"(cell adhesion)|go:"GO:0009650"(UV protection)|go:"GO:0010712"(regulation of collagen metabolic process)|go:"GO:0048251"(elastic fiber assembly)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0071953"(elastic fiber)|go:"GO:0097367"(carbohydrate derivative binding)|go:"GO:0097435"(supramolecular fiber organization)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR036056|reactome:R-HSA-2129379	-	-	-	figure legend:Fig. 6A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-dermal fibroblasts)|taxid:9606(Human dermal fibroblasts)	-	2014/02/06	2019/04/15	rogid:YEO0ZRTezrjEAyTaos1pm2hUDXg9606	rogid:pudRJmT0Rb32WgBHT7g7KZsSsME9606	intact-crc:9E1C1128EE62C159|rigid:aroHm/2CfailOZtphDxL22MHyto	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P55083	uniprotkb:P35555	intact:EBI-2829794|uniprotkb:Q6P680|uniprotkb:A8KAJ1|uniprotkb:A8MVM2|uniprotkb:B4E317|ensembl:ENSP00000299610	intact:EBI-2505934|ensembl:ENSP00000325527|uniprotkb:B2RUU0|uniprotkb:Q15972|uniprotkb:Q75N87|uniprotkb:D2JYH6	psi-mi:mfap4_human(display_long)|uniprotkb:MFAP4(gene name)|psi-mi:MFAP4(display_short)	psi-mi:fbn1_human(display_long)|uniprotkb:FBN1(gene name)|psi-mi:FBN1(display_short)|uniprotkb:FBN(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Kasamatsu et al. (2011)	pubmed:22355679|imex:IM-22574	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-9396651|imex:IM-22574-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001185624.1|refseq:NP_002395.1|ensembl:ENSG00000166482(gene)|ensembl:ENST00000299610(transcript)|go:"GO:0001527"(microfibril)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0003823"(antigen binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0007155"(cell adhesion)|go:"GO:0009650"(UV protection)|go:"GO:0010712"(regulation of collagen metabolic process)|go:"GO:0048251"(elastic fiber assembly)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0071953"(elastic fiber)|go:"GO:0097367"(carbohydrate derivative binding)|go:"GO:0097435"(supramolecular fiber organization)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR036056|reactome:R-HSA-2129379	ensembl:ENSG00000166147(gene)|ensembl:ENST00000316623(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001527"(microfibril)|go:"GO:0001656"(metanephros development)|go:"GO:0005178"(integrin binding)|go:"GO:0005179"(hormone activity)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0007507"(heart development)|go:"GO:0008201"(heparin binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030023"(extracellular matrix constituent conferring elasticity)|go:"GO:0031012"(extracellular matrix)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034199"(activation of protein kinase A activity)|go:"GO:0035582"(sequestering of BMP in extracellular matrix)|go:"GO:0035583"(sequestering of TGFbeta in extracellular matrix)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0048048"(embryonic eye morphogenesis)|go:"GO:0048050"(post-embryonic eye morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:2001205"(negative regulation of osteoclast development)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011398(Fibrillin)|interpro:IPR017878|interpro:IPR018097|interpro:IPR026823|interpro:IPR036773|interpro:IPR040872|mint:P35555|rcsb pdb:1APJ|rcsb pdb:1EMN|rcsb pdb:1EMO|rcsb pdb:1LMJ|rcsb pdb:1UZJ|rcsb pdb:1UZK|rcsb pdb:1UZP|rcsb pdb:1UZQ|rcsb pdb:2M74|rcsb pdb:2W86|rcsb pdb:5MS9|reactome:R-HSA-1474228|reactome:R-HSA-1566948|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-381426|reactome:R-HSA-8957275|refseq:NP_000129.3|dip:DIP-29985N	-	-	-	figure legend:Fig. 6B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-dermal fibroblasts)|taxid:9606(Human dermal fibroblasts)	-	2014/02/06	2019/04/15	rogid:pudRJmT0Rb32WgBHT7g7KZsSsME9606	rogid:YEO0ZRTezrjEAyTaos1pm2hUDXg9606	intact-crc:E5CD0DE871C0EF6E|rigid:aroHm/2CfailOZtphDxL22MHyto	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)