#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B intact:EBI-9870387 uniprotkb:P22449 - intact:EBI-5261592|uniprotkb:A2ICG9 psi-mi:soat2_human_hnf4a-site1_dna-probe(display_short)|psi-mi:EBI-9870387(display_long) psi-mi:hnf4a_rat(display_long)|uniprotkb:Hnf4a(gene name)|psi-mi:Hnf4a(display_short)|uniprotkb:Hnf-4(gene name synonym)|uniprotkb:Hnf4(gene name synonym)|uniprotkb:Nr2a1(gene name synonym)|uniprotkb:Tcf14(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group A member 1(gene name synonym)|uniprotkb:Transcription factor 14(gene name synonym)|uniprotkb:Transcription factor HNF-4(gene name synonym) psi-mi:"MI:0412"(electrophoretic mobility supershift assay) Zhang et al. (2012) imex:IM-23229|pubmed:22155889 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9870442|imex:IM-23229-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0319"(deoxyribonucleic acid) psi-mi:"MI:0326"(protein) ensembl:ENSG00000167780(see-also) rgd:2810|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|rcsb pdb:1M7W|refseq:NP_071516.2|interpro:IPR035500|interpro:IPR039067|reactome:R-RNO-383280|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003323"(type B pancreatic cell development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006591"(ornithine metabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006637"(acyl-CoA metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0007164"(establishment of tissue polarity)|go:"GO:0007548"(sex differentiation)|go:"GO:0007568"(aging)|go:"GO:0007596"(blood coagulation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009749"(response to glucose)|go:"GO:0010470"(regulation of gastrulation)|go:"GO:0016290"(palmitoyl-CoA hydrolase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032534"(regulation of microvillus assembly)|go:"GO:0036042"(long-chain fatty acyl-CoA binding)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0042493"|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051591"(response to cAMP)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0055091"(phospholipid homeostasis)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0070540"(stearic acid binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902569"(negative regulation of activation of Janus kinase activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding) - - - figure legend:Fig. 3a|dataset:Ulcerative colitis - Interactions of proteins identified as having a link to ulcerative colitis|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/10/23 2019/01/30 - rogid:5QEh/fyo3SYiVshcVoU5gCAMKU410116 intact-crc:6380EDD4D9B67CA1 false 32p radiolabel:?-? myc tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) intact:EBI-9870433 uniprotkb:P22449 - intact:EBI-5261592|uniprotkb:A2ICG9 psi-mi:soat2_human_hnf4a-site2_dna-probe(display_short)|psi-mi:EBI-9870433(display_long) psi-mi:hnf4a_rat(display_long)|uniprotkb:Hnf4a(gene name)|psi-mi:Hnf4a(display_short)|uniprotkb:Hnf-4(gene name synonym)|uniprotkb:Hnf4(gene name synonym)|uniprotkb:Nr2a1(gene name synonym)|uniprotkb:Tcf14(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group A member 1(gene name synonym)|uniprotkb:Transcription factor 14(gene name synonym)|uniprotkb:Transcription factor HNF-4(gene name synonym) psi-mi:"MI:0412"(electrophoretic mobility supershift assay) Zhang et al. (2012) imex:IM-23229|pubmed:22155889 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9871350|imex:IM-23229-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0319"(deoxyribonucleic acid) psi-mi:"MI:0326"(protein) ensembl:ENSG00000167780(see-also) rgd:2810|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|rcsb pdb:1M7W|refseq:NP_071516.2|interpro:IPR035500|interpro:IPR039067|reactome:R-RNO-383280|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003323"(type B pancreatic cell development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006591"(ornithine metabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006637"(acyl-CoA metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0007164"(establishment of tissue polarity)|go:"GO:0007548"(sex differentiation)|go:"GO:0007568"(aging)|go:"GO:0007596"(blood coagulation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009749"(response to glucose)|go:"GO:0010470"(regulation of gastrulation)|go:"GO:0016290"(palmitoyl-CoA hydrolase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032534"(regulation of microvillus assembly)|go:"GO:0036042"(long-chain fatty acyl-CoA binding)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0042493"|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051591"(response to cAMP)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0055091"(phospholipid homeostasis)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0070540"(stearic acid binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902569"(negative regulation of activation of Janus kinase activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding) - - - figure legend:Fig. 3a|dataset:Ulcerative colitis - Interactions of proteins identified as having a link to ulcerative colitis|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/10/23 2014/10/24 - rogid:5QEh/fyo3SYiVshcVoU5gCAMKU410116 intact-crc:AC3F470EE71CE2EC false 32p radiolabel:?-? myc tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) intact:EBI-9870436 uniprotkb:P22449 - intact:EBI-5261592|uniprotkb:A2ICG9 psi-mi:apoc3_human_hnf4a-site_dna-probe(display_short)|psi-mi:EBI-9870436(display_long) psi-mi:hnf4a_rat(display_long)|uniprotkb:Hnf4a(gene name)|psi-mi:Hnf4a(display_short)|uniprotkb:Hnf-4(gene name synonym)|uniprotkb:Hnf4(gene name synonym)|uniprotkb:Nr2a1(gene name synonym)|uniprotkb:Tcf14(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group A member 1(gene name synonym)|uniprotkb:Transcription factor 14(gene name synonym)|uniprotkb:Transcription factor HNF-4(gene name synonym) psi-mi:"MI:0412"(electrophoretic mobility supershift assay) Zhang et al. (2012) imex:IM-23229|pubmed:22155889 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9871358|imex:IM-23229-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0319"(deoxyribonucleic acid) psi-mi:"MI:0326"(protein) ensembl:ENSG00000110245(see-also) rgd:2810|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|rcsb pdb:1M7W|refseq:NP_071516.2|interpro:IPR035500|interpro:IPR039067|reactome:R-RNO-383280|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003323"(type B pancreatic cell development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006591"(ornithine metabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006637"(acyl-CoA metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0007164"(establishment of tissue polarity)|go:"GO:0007548"(sex differentiation)|go:"GO:0007568"(aging)|go:"GO:0007596"(blood coagulation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009749"(response to glucose)|go:"GO:0010470"(regulation of gastrulation)|go:"GO:0016290"(palmitoyl-CoA hydrolase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032534"(regulation of microvillus assembly)|go:"GO:0036042"(long-chain fatty acyl-CoA binding)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0042493"|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051591"(response to cAMP)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0055091"(phospholipid homeostasis)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0070540"(stearic acid binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902569"(negative regulation of activation of Janus kinase activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding) - - - figure legend:Fig. 3a|dataset:Ulcerative colitis - Interactions of proteins identified as having a link to ulcerative colitis|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/10/23 2014/10/24 - rogid:5QEh/fyo3SYiVshcVoU5gCAMKU410116 intact-crc:AD456A7A81158AFF false 32p radiolabel:?-? myc tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) intact:EBI-9870387 uniprotkb:P22449 - intact:EBI-5261592|uniprotkb:A2ICG9 psi-mi:soat2_human_hnf4a-site1_dna-probe(display_short)|psi-mi:EBI-9870387(display_long) psi-mi:hnf4a_rat(display_long)|uniprotkb:Hnf4a(gene name)|psi-mi:Hnf4a(display_short)|uniprotkb:Hnf-4(gene name synonym)|uniprotkb:Hnf4(gene name synonym)|uniprotkb:Nr2a1(gene name synonym)|uniprotkb:Tcf14(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group A member 1(gene name synonym)|uniprotkb:Transcription factor 14(gene name synonym)|uniprotkb:Transcription factor HNF-4(gene name synonym) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Zhang et al. (2012) imex:IM-23229|pubmed:22155889 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9870482|imex:IM-23229-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0319"(deoxyribonucleic acid) psi-mi:"MI:0326"(protein) ensembl:ENSG00000167780(see-also) rgd:2810|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|rcsb pdb:1M7W|refseq:NP_071516.2|interpro:IPR035500|interpro:IPR039067|reactome:R-RNO-383280|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003323"(type B pancreatic cell development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006591"(ornithine metabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006637"(acyl-CoA metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0007164"(establishment of tissue polarity)|go:"GO:0007548"(sex differentiation)|go:"GO:0007568"(aging)|go:"GO:0007596"(blood coagulation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009749"(response to glucose)|go:"GO:0010470"(regulation of gastrulation)|go:"GO:0016290"(palmitoyl-CoA hydrolase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032534"(regulation of microvillus assembly)|go:"GO:0036042"(long-chain fatty acyl-CoA binding)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0042493"|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051591"(response to cAMP)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0055091"(phospholipid homeostasis)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0070540"(stearic acid binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902569"(negative regulation of activation of Janus kinase activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding) - - - figure legend:Fig. 3a|dataset:Ulcerative colitis - Interactions of proteins identified as having a link to ulcerative colitis|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/10/23 2014/10/24 - rogid:5QEh/fyo3SYiVshcVoU5gCAMKU410116 intact-crc:07EAB110DECF40AC false 32p radiolabel:?-?|mutation disrupting interaction:?-? myc tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) intact:EBI-9870433 uniprotkb:P22449 - intact:EBI-5261592|uniprotkb:A2ICG9 psi-mi:soat2_human_hnf4a-site2_dna-probe(display_short)|psi-mi:EBI-9870433(display_long) psi-mi:hnf4a_rat(display_long)|uniprotkb:Hnf4a(gene name)|psi-mi:Hnf4a(display_short)|uniprotkb:Hnf-4(gene name synonym)|uniprotkb:Hnf4(gene name synonym)|uniprotkb:Nr2a1(gene name synonym)|uniprotkb:Tcf14(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group A member 1(gene name synonym)|uniprotkb:Transcription factor 14(gene name synonym)|uniprotkb:Transcription factor HNF-4(gene name synonym) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Zhang et al. (2012) imex:IM-23229|pubmed:22155889 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9871295|imex:IM-23229-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0319"(deoxyribonucleic acid) psi-mi:"MI:0326"(protein) ensembl:ENSG00000167780(see-also) rgd:2810|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|rcsb pdb:1M7W|refseq:NP_071516.2|interpro:IPR035500|interpro:IPR039067|reactome:R-RNO-383280|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003323"(type B pancreatic cell development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006591"(ornithine metabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006637"(acyl-CoA metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0007164"(establishment of tissue polarity)|go:"GO:0007548"(sex differentiation)|go:"GO:0007568"(aging)|go:"GO:0007596"(blood coagulation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009749"(response to glucose)|go:"GO:0010470"(regulation of gastrulation)|go:"GO:0016290"(palmitoyl-CoA hydrolase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032534"(regulation of microvillus assembly)|go:"GO:0036042"(long-chain fatty acyl-CoA binding)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0042493"|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051591"(response to cAMP)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0055091"(phospholipid homeostasis)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0070540"(stearic acid binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902569"(negative regulation of activation of Janus kinase activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding) - - - figure legend:Fig. 3a|dataset:Ulcerative colitis - Interactions of proteins identified as having a link to ulcerative colitis|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/10/23 2019/01/30 - rogid:5QEh/fyo3SYiVshcVoU5gCAMKU410116 intact-crc:055743DB54629DF5 false 32p radiolabel:?-?|mutation disrupting interaction:?-? myc tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:P22449 intact:EBI-9870436 intact:EBI-5261592|uniprotkb:A2ICG9 - psi-mi:hnf4a_rat(display_long)|uniprotkb:Hnf4a(gene name)|psi-mi:Hnf4a(display_short)|uniprotkb:Hnf-4(gene name synonym)|uniprotkb:Hnf4(gene name synonym)|uniprotkb:Nr2a1(gene name synonym)|uniprotkb:Tcf14(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group A member 1(gene name synonym)|uniprotkb:Transcription factor 14(gene name synonym)|uniprotkb:Transcription factor HNF-4(gene name synonym) psi-mi:apoc3_human_hnf4a-site_dna-probe(display_short)|psi-mi:EBI-9870436(display_long) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Zhang et al. (2012) imex:IM-23229|pubmed:22155889 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9871305|imex:IM-23229-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0319"(deoxyribonucleic acid) rgd:2810|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|rcsb pdb:1M7W|refseq:NP_071516.2|interpro:IPR035500|interpro:IPR039067|reactome:R-RNO-383280|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003323"(type B pancreatic cell development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006591"(ornithine metabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006637"(acyl-CoA metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0007164"(establishment of tissue polarity)|go:"GO:0007548"(sex differentiation)|go:"GO:0007568"(aging)|go:"GO:0007596"(blood coagulation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009749"(response to glucose)|go:"GO:0010470"(regulation of gastrulation)|go:"GO:0016290"(palmitoyl-CoA hydrolase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032534"(regulation of microvillus assembly)|go:"GO:0036042"(long-chain fatty acyl-CoA binding)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0042493"|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051591"(response to cAMP)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0055091"(phospholipid homeostasis)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0070540"(stearic acid binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902569"(negative regulation of activation of Janus kinase activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding) ensembl:ENSG00000110245(see-also) - - - figure legend:Fig. 3a|dataset:Ulcerative colitis - Interactions of proteins identified as having a link to ulcerative colitis|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/10/23 2019/01/30 rogid:5QEh/fyo3SYiVshcVoU5gCAMKU410116 - intact-crc:042D6EAF326BF5E6 false myc tag:?-? 32p radiolabel:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) ensembl:ENSG00000167780 uniprotkb:P41235 intact:EBI-9870565 intact:EBI-1049011|uniprotkb:Q92654|uniprotkb:Q92655|uniprotkb:Q99864|uniprotkb:Q9NQH0|uniprotkb:O00659|uniprotkb:O00723|uniprotkb:Q14540|uniprotkb:Q5QPB8|uniprotkb:Q6B4V5|uniprotkb:Q6B4V6|uniprotkb:Q6B4V7|uniprotkb:Q92653|uniprotkb:A5JW41|uniprotkb:B2RPP8|ensembl:ENSP00000312987 psi-mi:soat2_human_gene(display_short)|psi-mi:ENSG00000167780(display_long) psi-mi:hnf4a_human(display_long)|uniprotkb:Transcription factor HNF-4(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group A member 1(gene name synonym)|uniprotkb:Transcription factor 14(gene name synonym)|uniprotkb:HNF4A(gene name)|psi-mi:HNF4A(display_short)|uniprotkb:HNF4(gene name synonym)|uniprotkb:NR2A1(gene name synonym)|uniprotkb:TCF14(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Zhang et al. (2012) imex:IM-23229|pubmed:22155889 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9870572|imex:IM-23229-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_000448.3|refseq:NP_001025174.1|refseq:NP_001025175.1|refseq:NP_787110.2|refseq:NP_849181.1|refseq:NP_001274111.1|refseq:NP_001274112.1|refseq:NP_001274113.1|refseq:NP_001245284.1|ensembl:ENSG00000101076(gene)|ensembl:ENST00000316099(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003323"(type B pancreatic cell development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006591"(ornithine metabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0007548"(sex differentiation)|go:"GO:0007596"(blood coagulation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009749"(response to glucose)|go:"GO:0010470"(regulation of gastrulation)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0055091"(phospholipid homeostasis)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0060398"(regulation of growth hormone receptor signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|interpro:IPR039067|mint:P41235|rcsb pdb:1PZL|rcsb pdb:3CBB|rcsb pdb:3FS1|rcsb pdb:4B7W|rcsb pdb:4IQR|rcsb pdb:6CHT|reactome:R-HSA-210745|reactome:R-HSA-383280|dip:DIP-499N - - - figure legend:Fig. 3b|causality statement:P41235 increases expression at RNA level of ENSG00000167780|dataset:Ulcerative colitis - Interactions of proteins identified as having a link to ulcerative colitis|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hep_g2)|taxid:9606("Homo sapiens hepatocellular carcinoma (HCC) cells (p53-wt).") - 2014/10/23 2019/01/30 - rogid:lul0rM/fHNAVsH3ZizbMOXPPL0k9606 intact-crc:26EBC0C4CC65B550 false binding-associated region:?-?|binding-associated region:?-? - - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr) uniprotkb:P41235 ensembl:ENSG00000197249 intact:EBI-1049011|uniprotkb:Q92654|uniprotkb:Q92655|uniprotkb:Q99864|uniprotkb:Q9NQH0|uniprotkb:O00659|uniprotkb:O00723|uniprotkb:Q14540|uniprotkb:Q5QPB8|uniprotkb:Q6B4V5|uniprotkb:Q6B4V6|uniprotkb:Q6B4V7|uniprotkb:Q92653|uniprotkb:A5JW41|uniprotkb:B2RPP8|ensembl:ENSP00000312987 intact:EBI-9871400 psi-mi:hnf4a_human(display_long)|uniprotkb:Transcription factor HNF-4(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group A member 1(gene name synonym)|uniprotkb:Transcription factor 14(gene name synonym)|uniprotkb:HNF4A(gene name)|psi-mi:HNF4A(display_short)|uniprotkb:HNF4(gene name synonym)|uniprotkb:NR2A1(gene name synonym)|uniprotkb:TCF14(gene name synonym) psi-mi:a1at_human_gene(display_short)|psi-mi:ENSG00000197249(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Zhang et al. (2012) imex:IM-23229|pubmed:22155889 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9871403|imex:IM-23229-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_000448.3|refseq:NP_001025174.1|refseq:NP_001025175.1|refseq:NP_787110.2|refseq:NP_849181.1|refseq:NP_001274111.1|refseq:NP_001274112.1|refseq:NP_001274113.1|refseq:NP_001245284.1|ensembl:ENSG00000101076(gene)|ensembl:ENST00000316099(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003323"(type B pancreatic cell development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006591"(ornithine metabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0007548"(sex differentiation)|go:"GO:0007596"(blood coagulation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009749"(response to glucose)|go:"GO:0010470"(regulation of gastrulation)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0055091"(phospholipid homeostasis)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0060398"(regulation of growth hormone receptor signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|interpro:IPR039067|mint:P41235|rcsb pdb:1PZL|rcsb pdb:3CBB|rcsb pdb:3FS1|rcsb pdb:4B7W|rcsb pdb:4IQR|rcsb pdb:6CHT|reactome:R-HSA-210745|reactome:R-HSA-383280|dip:DIP-499N - - - - figure legend:Fig. 3b|dataset:Ulcerative colitis - Interactions of proteins identified as having a link to ulcerative colitis|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hep_g2)|taxid:9606("Homo sapiens hepatocellular carcinoma (HCC) cells (p53-wt).") - 2014/10/23 2019/01/30 rogid:lul0rM/fHNAVsH3ZizbMOXPPL0k9606 - intact-crc:D6E25D2A2A47C3B5 false - binding-associated region:?-? - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr)