#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
intact:EBI-9120329	uniprotkb:F1SMV2	-	intact:EBI-9120317|ensembl:ENSSSCP00000017246	psi-mi:i3lfi0_pig(display_short)|psi-mi:EBI-9120329(display_long)|uniprotkb:RAC1(gene name)|psi-mi:RAC1(display_short)	psi-mi:f1smv2_pig(display_long)|uniprotkb:PDE6D(gene name)|psi-mi:PDE6D(display_short)	psi-mi:"MI:0276"(blue native page)	Kiel et al. (2011)	pubmed:22108793|imex:IM-22275	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9120315|imex:IM-22275-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:I3LFI0(uniprot-removed-ac)	ensembl:ENSSSCG00000016279(gene)|ensembl:ENSSSCT00000017727(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007601"(visual perception)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0050896"(response to stimulus)|interpro:IPR008015(GMP phosphodiesterase, delta subunit)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017287(Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit)|interpro:IPR037036	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:7A|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9823(pig-retina-rod_outer_segment)|taxid:9823(Pig Rod Outer Segment)	-	2014/02/07	2020/01/08	rogid:Bqh8T7zsIT20kEzmgRNoARFsM/Y9823	rogid:L2Tkb0ytcqjo256FCH5gHO4mP3o9823	intact-crc:201ED378A293B504|rigid:vqEdrIpiSHKUPxYLby1TJkl9PvE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P02866	uniprotkb:I3LJE2	intact:EBI-2905940|uniprotkb:Q947H0	intact:EBI-9160576|ensembl:ENSSSCP00000024202	psi-mi:cona_canen(display_long)	psi-mi:i3lje2_pig(display_long)|uniprotkb:DPYSL2(gene name)|psi-mi:DPYSL2(display_short)	psi-mi:"MI:0096"(pull down)	Kiel et al. (2011)	pubmed:22108793|imex:IM-22275	taxid:3823(canen)|taxid:3823("Canavalia ensiformis (Jack bean)")	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9160608|imex:IM-22275-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:5Z5L|rcsb pdb:6H2M|rcsb pdb:5Z5Y|rcsb pdb:5ZAC|go:"GO:0005537"(mannose binding)|go:"GO:0046872"(metal ion binding)|rcsb pdb:4P9W|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR016363(L-type lectin, plant)|interpro:IPR000985(Legume lectin, alpha)|interpro:IPR001220(Legume lectin, beta domain)|interpro:IPR019825|rcsb pdb:1APN|rcsb pdb:1BXH|rcsb pdb:1C57|rcsb pdb:1CES|rcsb pdb:1CJP|rcsb pdb:1CN1|rcsb pdb:1CON|rcsb pdb:1CVN|rcsb pdb:1DQ0|rcsb pdb:1DQ1|rcsb pdb:1DQ2|rcsb pdb:1DQ4|rcsb pdb:1DQ5|rcsb pdb:1DQ6|rcsb pdb:1ENQ|rcsb pdb:1ENR|rcsb pdb:1ENS|rcsb pdb:1GIC|rcsb pdb:1GKB|rcsb pdb:1HQW|rcsb pdb:1I3H|rcsb pdb:1JBC|rcsb pdb:1JN2|rcsb pdb:1JOJ|rcsb pdb:1JUI|rcsb pdb:1JW6|rcsb pdb:1JYC|rcsb pdb:1JYI|rcsb pdb:1NLS|rcsb pdb:1NXD|rcsb pdb:1ONA|rcsb pdb:1QGL|rcsb pdb:1QNY|rcsb pdb:1SCR|rcsb pdb:1SCS|rcsb pdb:1TEI|rcsb pdb:1VAL|rcsb pdb:1VAM|rcsb pdb:1XQN|rcsb pdb:2CNA|rcsb pdb:2CTV|rcsb pdb:2ENR|rcsb pdb:2UU8|rcsb pdb:2YZ4|rcsb pdb:3CNA|rcsb pdb:3D4K|rcsb pdb:3ENR|rcsb pdb:3NWK|rcsb pdb:5CNA|rcsb pdb:4PF5|rcsb pdb:4P9Y|rcsb pdb:4P9X|rcsb pdb:7MG1|rcsb pdb:7MG2|rcsb pdb:7MG3|rcsb pdb:7MG4|rcsb pdb:7MG5|rcsb pdb:7MG6|rcsb pdb:7MG7|rcsb pdb:7MG8|rcsb pdb:7MG9|rcsb pdb:7MGA|rcsb pdb:7MGB|rcsb pdb:7MGC|rcsb pdb:7MGD|rcsb pdb:5O6N|rcsb pdb:5WEY|rcsb pdb:5Z5N|rcsb pdb:5Z5P|rcsb pdb:6AHG|rcsb pdb:6XT6	ensembl:ENSSSCG00000030130(gene)|ensembl:ENSSSCT00000031898(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0016810"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds")|go:"GO:0030516"(regulation of axon extension)|go:"GO:0045664"(regulation of neuron differentiation)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011778(D-hydantoinase)|interpro:IPR030615|interpro:IPR032466	-	-	-	figure legend:Supp 6C|antagonist:"AMM:-methylmannoside -lowers the affinity of proteins for the beads."|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/02/07	2020/01/08	rogid:bFjmZn0Tru2vk/55DVNqFIEuh+A3823	rogid:I1Gl8U+F3Qrtu5rVmxzZO+GDrGQ9823	intact-crc:BB4DC2B6D5B23437|rigid:zzET1baxZ3meuTNs8qTcOHh80nk	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P02866	uniprotkb:O18766	intact:EBI-2905940|uniprotkb:Q947H0	intact:EBI-9160309|ensembl:ENSSSCP00000012353|ensembl:ENSSSCP00005029658|ensembl:ENSSSCP00015029990|ensembl:ENSSSCP00025015998|ensembl:ENSSSCP00030027215|ensembl:ENSSSCP00035043667|ensembl:ENSSSCP00040030713|ensembl:ENSSSCP00045006043|ensembl:ENSSSCP00050000602|ensembl:ENSSSCP00055017796|ensembl:ENSSSCP00060008807|ensembl:ENSSSCP00065005502	psi-mi:cona_canen(display_long)	psi-mi:opsd_pig(display_long)|uniprotkb:RHO(gene name)|psi-mi:RHO(display_short)|uniprotkb:RHO1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kiel et al. (2011)	pubmed:22108793|imex:IM-22275	taxid:3823(canen)|taxid:3823("Canavalia ensiformis (Jack bean)")	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9160608|imex:IM-22275-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:5Z5L|rcsb pdb:6H2M|rcsb pdb:5Z5Y|rcsb pdb:5ZAC|go:"GO:0005537"(mannose binding)|go:"GO:0046872"(metal ion binding)|rcsb pdb:4P9W|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR016363(L-type lectin, plant)|interpro:IPR000985(Legume lectin, alpha)|interpro:IPR001220(Legume lectin, beta domain)|interpro:IPR019825|rcsb pdb:1APN|rcsb pdb:1BXH|rcsb pdb:1C57|rcsb pdb:1CES|rcsb pdb:1CJP|rcsb pdb:1CN1|rcsb pdb:1CON|rcsb pdb:1CVN|rcsb pdb:1DQ0|rcsb pdb:1DQ1|rcsb pdb:1DQ2|rcsb pdb:1DQ4|rcsb pdb:1DQ5|rcsb pdb:1DQ6|rcsb pdb:1ENQ|rcsb pdb:1ENR|rcsb pdb:1ENS|rcsb pdb:1GIC|rcsb pdb:1GKB|rcsb pdb:1HQW|rcsb pdb:1I3H|rcsb pdb:1JBC|rcsb pdb:1JN2|rcsb pdb:1JOJ|rcsb pdb:1JUI|rcsb pdb:1JW6|rcsb pdb:1JYC|rcsb pdb:1JYI|rcsb pdb:1NLS|rcsb pdb:1NXD|rcsb pdb:1ONA|rcsb pdb:1QGL|rcsb pdb:1QNY|rcsb pdb:1SCR|rcsb pdb:1SCS|rcsb pdb:1TEI|rcsb pdb:1VAL|rcsb pdb:1VAM|rcsb pdb:1XQN|rcsb pdb:2CNA|rcsb pdb:2CTV|rcsb pdb:2ENR|rcsb pdb:2UU8|rcsb pdb:2YZ4|rcsb pdb:3CNA|rcsb pdb:3D4K|rcsb pdb:3ENR|rcsb pdb:3NWK|rcsb pdb:5CNA|rcsb pdb:4PF5|rcsb pdb:4P9Y|rcsb pdb:4P9X|rcsb pdb:7MG1|rcsb pdb:7MG2|rcsb pdb:7MG3|rcsb pdb:7MG4|rcsb pdb:7MG5|rcsb pdb:7MG6|rcsb pdb:7MG7|rcsb pdb:7MG8|rcsb pdb:7MG9|rcsb pdb:7MGA|rcsb pdb:7MGB|rcsb pdb:7MGC|rcsb pdb:7MGD|rcsb pdb:5O6N|rcsb pdb:5WEY|rcsb pdb:5Z5N|rcsb pdb:5Z5P|rcsb pdb:6AHG|rcsb pdb:6XT6	refseq:NP_999386.1|go:"GO:0007601"(visual perception)|go:"GO:0007602"(phototransduction)|go:"GO:0008020"(G protein-coupled photoreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016038"(absorption of visible light)|go:"GO:0016056"(rhodopsin mediated signaling pathway)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0042622"(photoreceptor outer segment membrane)|go:"GO:0043052"(thermotaxis)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0046872"(metal ion binding)|go:"GO:0050960"(detection of temperature stimulus involved in thermoception)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060342"(photoreceptor inner segment membrane)|go:"GO:0071482"(cellular response to light stimulus)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097381"(photoreceptor disc membrane)|go:"GO:1990913"(sperm head plasma membrane)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000732(Rhodopsin)|interpro:IPR001760(Opsin)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR019477|interpro:IPR027430|reactome:R-SSC-2453902|reactome:R-SSC-2485179|reactome:R-SSC-2514859|reactome:R-SSC-418594|reactome:R-SSC-419771|reactome:R-SSC-5620916|ensembl:ENSSSCG00000011590(gene)|ensembl:ENSSSCG00005030296(gene)|ensembl:ENSSSCG00015056060(gene)|ensembl:ENSSSCG00025027966(gene)|ensembl:ENSSSCG00030042653(gene)|ensembl:ENSSSCG00035075320(gene)|ensembl:ENSSSCG00040053115(gene)|ensembl:ENSSSCG00045005359(gene)|ensembl:ENSSSCG00050001576(gene)|ensembl:ENSSSCG00055011447(gene)|ensembl:ENSSSCG00060016077(gene)|ensembl:ENSSSCG00065010157(gene)|ensembl:ENSSSCT00000012686(transcript)|ensembl:ENSSSCT00005048157(transcript)|ensembl:ENSSSCT00015074764(transcript)|ensembl:ENSSSCT00025037995(transcript)|ensembl:ENSSSCT00030059461(transcript)|ensembl:ENSSSCT00035102385(transcript)|ensembl:ENSSSCT00040071930(transcript)|ensembl:ENSSSCT00045008896(transcript)|ensembl:ENSSSCT00050001985(transcript)|ensembl:ENSSSCT00055022503(transcript)|ensembl:ENSSSCT00060021418(transcript)|ensembl:ENSSSCT00065013494(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005502"(11-cis retinal binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)	-	-	-	figure legend:Supp 6C|antagonist:"AMM:-methylmannoside -lowers the affinity of proteins for the beads."|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/02/07	2020/01/08	rogid:bFjmZn0Tru2vk/55DVNqFIEuh+A3823	rogid:Tcoo4Tpb9FImJjcycBX9l6KHUDs9823	intact-crc:BB4DC2B6D5B23437|rigid:zzET1baxZ3meuTNs8qTcOHh80nk	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P02866	uniprotkb:I3LA61	intact:EBI-2905940|uniprotkb:Q947H0	intact:EBI-9160336|ensembl:ENSSSCP00000020927	psi-mi:cona_canen(display_long)	psi-mi:i3la61_pig(display_long)|uniprotkb:GNAT1(gene name)|psi-mi:GNAT1(display_short)	psi-mi:"MI:0096"(pull down)	Kiel et al. (2011)	pubmed:22108793|imex:IM-22275	taxid:3823(canen)|taxid:3823("Canavalia ensiformis (Jack bean)")	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9160608|imex:IM-22275-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:5Z5L|rcsb pdb:6H2M|rcsb pdb:5Z5Y|rcsb pdb:5ZAC|go:"GO:0005537"(mannose binding)|go:"GO:0046872"(metal ion binding)|rcsb pdb:4P9W|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR016363(L-type lectin, plant)|interpro:IPR000985(Legume lectin, alpha)|interpro:IPR001220(Legume lectin, beta domain)|interpro:IPR019825|rcsb pdb:1APN|rcsb pdb:1BXH|rcsb pdb:1C57|rcsb pdb:1CES|rcsb pdb:1CJP|rcsb pdb:1CN1|rcsb pdb:1CON|rcsb pdb:1CVN|rcsb pdb:1DQ0|rcsb pdb:1DQ1|rcsb pdb:1DQ2|rcsb pdb:1DQ4|rcsb pdb:1DQ5|rcsb pdb:1DQ6|rcsb pdb:1ENQ|rcsb pdb:1ENR|rcsb pdb:1ENS|rcsb pdb:1GIC|rcsb pdb:1GKB|rcsb pdb:1HQW|rcsb pdb:1I3H|rcsb pdb:1JBC|rcsb pdb:1JN2|rcsb pdb:1JOJ|rcsb pdb:1JUI|rcsb pdb:1JW6|rcsb pdb:1JYC|rcsb pdb:1JYI|rcsb pdb:1NLS|rcsb pdb:1NXD|rcsb pdb:1ONA|rcsb pdb:1QGL|rcsb pdb:1QNY|rcsb pdb:1SCR|rcsb pdb:1SCS|rcsb pdb:1TEI|rcsb pdb:1VAL|rcsb pdb:1VAM|rcsb pdb:1XQN|rcsb pdb:2CNA|rcsb pdb:2CTV|rcsb pdb:2ENR|rcsb pdb:2UU8|rcsb pdb:2YZ4|rcsb pdb:3CNA|rcsb pdb:3D4K|rcsb pdb:3ENR|rcsb pdb:3NWK|rcsb pdb:5CNA|rcsb pdb:4PF5|rcsb pdb:4P9Y|rcsb pdb:4P9X|rcsb pdb:7MG1|rcsb pdb:7MG2|rcsb pdb:7MG3|rcsb pdb:7MG4|rcsb pdb:7MG5|rcsb pdb:7MG6|rcsb pdb:7MG7|rcsb pdb:7MG8|rcsb pdb:7MG9|rcsb pdb:7MGA|rcsb pdb:7MGB|rcsb pdb:7MGC|rcsb pdb:7MGD|rcsb pdb:5O6N|rcsb pdb:5WEY|rcsb pdb:5Z5N|rcsb pdb:5Z5P|rcsb pdb:6AHG|rcsb pdb:6XT6	ensembl:ENSSSCG00000042718(gene)|ensembl:ENSSSCT00000031793(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0009416"(response to light stimulus)|go:"GO:0016020"(membrane)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417	-	-	-	figure legend:Supp 6C|antagonist:"AMM:-methylmannoside -lowers the affinity of proteins for the beads."|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/02/07	2020/01/08	rogid:bFjmZn0Tru2vk/55DVNqFIEuh+A3823	rogid:SiGOVBLsD1pZ3qp3/OgAtFpWlmw9823	intact-crc:BB4DC2B6D5B23437|rigid:zzET1baxZ3meuTNs8qTcOHh80nk	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:I3LA61	uniprotkb:O18766	intact:EBI-9160336|ensembl:ENSSSCP00000020927	intact:EBI-9160309|ensembl:ENSSSCP00000012353|ensembl:ENSSSCP00005029658|ensembl:ENSSSCP00015029990|ensembl:ENSSSCP00025015998|ensembl:ENSSSCP00030027215|ensembl:ENSSSCP00035043667|ensembl:ENSSSCP00040030713|ensembl:ENSSSCP00045006043|ensembl:ENSSSCP00050000602|ensembl:ENSSSCP00055017796|ensembl:ENSSSCP00060008807|ensembl:ENSSSCP00065005502	psi-mi:i3la61_pig(display_long)|uniprotkb:GNAT1(gene name)|psi-mi:GNAT1(display_short)	psi-mi:opsd_pig(display_long)|uniprotkb:RHO(gene name)|psi-mi:RHO(display_short)|uniprotkb:RHO1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Kiel et al. (2011)	pubmed:22108793|imex:IM-22275	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9160628|imex:IM-22275-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSSSCG00000042718(gene)|ensembl:ENSSSCT00000031793(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0009416"(response to light stimulus)|go:"GO:0016020"(membrane)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417	refseq:NP_999386.1|go:"GO:0007601"(visual perception)|go:"GO:0007602"(phototransduction)|go:"GO:0008020"(G protein-coupled photoreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016038"(absorption of visible light)|go:"GO:0016056"(rhodopsin mediated signaling pathway)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0042622"(photoreceptor outer segment membrane)|go:"GO:0043052"(thermotaxis)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0046872"(metal ion binding)|go:"GO:0050960"(detection of temperature stimulus involved in thermoception)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060342"(photoreceptor inner segment membrane)|go:"GO:0071482"(cellular response to light stimulus)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097381"(photoreceptor disc membrane)|go:"GO:1990913"(sperm head plasma membrane)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000732(Rhodopsin)|interpro:IPR001760(Opsin)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR019477|interpro:IPR027430|reactome:R-SSC-2453902|reactome:R-SSC-2485179|reactome:R-SSC-2514859|reactome:R-SSC-418594|reactome:R-SSC-419771|reactome:R-SSC-5620916|ensembl:ENSSSCG00000011590(gene)|ensembl:ENSSSCG00005030296(gene)|ensembl:ENSSSCG00015056060(gene)|ensembl:ENSSSCG00025027966(gene)|ensembl:ENSSSCG00030042653(gene)|ensembl:ENSSSCG00035075320(gene)|ensembl:ENSSSCG00040053115(gene)|ensembl:ENSSSCG00045005359(gene)|ensembl:ENSSSCG00050001576(gene)|ensembl:ENSSSCG00055011447(gene)|ensembl:ENSSSCG00060016077(gene)|ensembl:ENSSSCG00065010157(gene)|ensembl:ENSSSCT00000012686(transcript)|ensembl:ENSSSCT00005048157(transcript)|ensembl:ENSSSCT00015074764(transcript)|ensembl:ENSSSCT00025037995(transcript)|ensembl:ENSSSCT00030059461(transcript)|ensembl:ENSSSCT00035102385(transcript)|ensembl:ENSSSCT00040071930(transcript)|ensembl:ENSSSCT00045008896(transcript)|ensembl:ENSSSCT00050001985(transcript)|ensembl:ENSSSCT00055022503(transcript)|ensembl:ENSSSCT00060021418(transcript)|ensembl:ENSSSCT00065013494(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005502"(11-cis retinal binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)	-	-	-	figure legend:Supp 6D|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9823(pig-retina-rod_outer_segment)|taxid:9823(Pig Rod Outer Segment)	-	2014/02/07	2020/01/08	rogid:SiGOVBLsD1pZ3qp3/OgAtFpWlmw9823	rogid:Tcoo4Tpb9FImJjcycBX9l6KHUDs9823	intact-crc:5A69744A62AFB979|rigid:Ip5g3jr8C3dbrpV1m2kqdDZI0aI	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:I3LA61	intact:EBI-9120329	intact:EBI-9160336|ensembl:ENSSSCP00000020927	-	psi-mi:i3la61_pig(display_long)|uniprotkb:GNAT1(gene name)|psi-mi:GNAT1(display_short)	psi-mi:i3lfi0_pig(display_short)|psi-mi:EBI-9120329(display_long)|uniprotkb:RAC1(gene name)|psi-mi:RAC1(display_short)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Kiel et al. (2011)	pubmed:22108793|imex:IM-22275	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9160509|imex:IM-22275-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSSSCG00000042718(gene)|ensembl:ENSSSCT00000031793(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0009416"(response to light stimulus)|go:"GO:0016020"(membrane)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417	uniprotkb:I3LFI0(uniprot-removed-ac)	-	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Supp 6A|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9823(pig-retina-rod_outer_segment)|taxid:9823(Pig Rod Outer Segment)	-	2014/02/07	2020/01/08	rogid:SiGOVBLsD1pZ3qp3/OgAtFpWlmw9823	rogid:Bqh8T7zsIT20kEzmgRNoARFsM/Y9823	intact-crc:67E7E20A89D54593|rigid:gvxRxsA12jjQIfn9rrPmTlvH87U	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:I3LA61	uniprotkb:I3LJE2	intact:EBI-9160336|ensembl:ENSSSCP00000020927	intact:EBI-9160576|ensembl:ENSSSCP00000024202	psi-mi:i3la61_pig(display_long)|uniprotkb:GNAT1(gene name)|psi-mi:GNAT1(display_short)	psi-mi:i3lje2_pig(display_long)|uniprotkb:DPYSL2(gene name)|psi-mi:DPYSL2(display_short)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Kiel et al. (2011)	pubmed:22108793|imex:IM-22275	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9160509|imex:IM-22275-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSSSCG00000042718(gene)|ensembl:ENSSSCT00000031793(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0009416"(response to light stimulus)|go:"GO:0016020"(membrane)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417	ensembl:ENSSSCG00000030130(gene)|ensembl:ENSSSCT00000031898(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0016810"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds")|go:"GO:0030516"(regulation of axon extension)|go:"GO:0045664"(regulation of neuron differentiation)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011778(D-hydantoinase)|interpro:IPR030615|interpro:IPR032466	-	-	-	figure legend:Supp 6A|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9823(pig-retina-rod_outer_segment)|taxid:9823(Pig Rod Outer Segment)	-	2014/02/07	2020/01/08	rogid:SiGOVBLsD1pZ3qp3/OgAtFpWlmw9823	rogid:I1Gl8U+F3Qrtu5rVmxzZO+GDrGQ9823	intact-crc:67E7E20A89D54593|rigid:gvxRxsA12jjQIfn9rrPmTlvH87U	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:I3LA61	uniprotkb:O18766	intact:EBI-9160336|ensembl:ENSSSCP00000020927	intact:EBI-9160309|ensembl:ENSSSCP00000012353|ensembl:ENSSSCP00005029658|ensembl:ENSSSCP00015029990|ensembl:ENSSSCP00025015998|ensembl:ENSSSCP00030027215|ensembl:ENSSSCP00035043667|ensembl:ENSSSCP00040030713|ensembl:ENSSSCP00045006043|ensembl:ENSSSCP00050000602|ensembl:ENSSSCP00055017796|ensembl:ENSSSCP00060008807|ensembl:ENSSSCP00065005502	psi-mi:i3la61_pig(display_long)|uniprotkb:GNAT1(gene name)|psi-mi:GNAT1(display_short)	psi-mi:opsd_pig(display_long)|uniprotkb:RHO(gene name)|psi-mi:RHO(display_short)|uniprotkb:RHO1(gene name synonym)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Kiel et al. (2011)	pubmed:22108793|imex:IM-22275	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9160509|imex:IM-22275-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSSSCG00000042718(gene)|ensembl:ENSSSCT00000031793(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0009416"(response to light stimulus)|go:"GO:0016020"(membrane)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417	refseq:NP_999386.1|go:"GO:0007601"(visual perception)|go:"GO:0007602"(phototransduction)|go:"GO:0008020"(G protein-coupled photoreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016038"(absorption of visible light)|go:"GO:0016056"(rhodopsin mediated signaling pathway)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0042622"(photoreceptor outer segment membrane)|go:"GO:0043052"(thermotaxis)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0046872"(metal ion binding)|go:"GO:0050960"(detection of temperature stimulus involved in thermoception)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060342"(photoreceptor inner segment membrane)|go:"GO:0071482"(cellular response to light stimulus)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097381"(photoreceptor disc membrane)|go:"GO:1990913"(sperm head plasma membrane)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000732(Rhodopsin)|interpro:IPR001760(Opsin)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR019477|interpro:IPR027430|reactome:R-SSC-2453902|reactome:R-SSC-2485179|reactome:R-SSC-2514859|reactome:R-SSC-418594|reactome:R-SSC-419771|reactome:R-SSC-5620916|ensembl:ENSSSCG00000011590(gene)|ensembl:ENSSSCG00005030296(gene)|ensembl:ENSSSCG00015056060(gene)|ensembl:ENSSSCG00025027966(gene)|ensembl:ENSSSCG00030042653(gene)|ensembl:ENSSSCG00035075320(gene)|ensembl:ENSSSCG00040053115(gene)|ensembl:ENSSSCG00045005359(gene)|ensembl:ENSSSCG00050001576(gene)|ensembl:ENSSSCG00055011447(gene)|ensembl:ENSSSCG00060016077(gene)|ensembl:ENSSSCG00065010157(gene)|ensembl:ENSSSCT00000012686(transcript)|ensembl:ENSSSCT00005048157(transcript)|ensembl:ENSSSCT00015074764(transcript)|ensembl:ENSSSCT00025037995(transcript)|ensembl:ENSSSCT00030059461(transcript)|ensembl:ENSSSCT00035102385(transcript)|ensembl:ENSSSCT00040071930(transcript)|ensembl:ENSSSCT00045008896(transcript)|ensembl:ENSSSCT00050001985(transcript)|ensembl:ENSSSCT00055022503(transcript)|ensembl:ENSSSCT00060021418(transcript)|ensembl:ENSSSCT00065013494(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005502"(11-cis retinal binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)	-	-	-	figure legend:Supp 6A|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9823(pig-retina-rod_outer_segment)|taxid:9823(Pig Rod Outer Segment)	-	2014/02/07	2020/01/08	rogid:SiGOVBLsD1pZ3qp3/OgAtFpWlmw9823	rogid:Tcoo4Tpb9FImJjcycBX9l6KHUDs9823	intact-crc:67E7E20A89D54593|rigid:gvxRxsA12jjQIfn9rrPmTlvH87U	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:I3LA61	uniprotkb:M3TYT0	intact:EBI-9160336|ensembl:ENSSSCP00000020927	intact:EBI-9160518|uniprotkb:F1SCR1|ensembl:ENSSSCP00050017010|ensembl:ENSSSCP00055007146|ensembl:ENSSSCP00065034131	psi-mi:i3la61_pig(display_long)|uniprotkb:GNAT1(gene name)|psi-mi:GNAT1(display_short)	psi-mi:rock2_pig(display_long)|uniprotkb:ROCK2(gene name)|psi-mi:ROCK2(display_short)|uniprotkb:Rho kinase 2(gene name synonym)|uniprotkb:Rho-associated, coiled-coil-containing protein kinase 2(gene name synonym)|uniprotkb:Rho-associated, coiled-coil-containing protein kinase II(gene name synonym)|uniprotkb:p164 ROCK-2(gene name synonym)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Kiel et al. (2011)	pubmed:22108793|imex:IM-22275	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9160509|imex:IM-22275-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSSSCG00000042718(gene)|ensembl:ENSSSCT00000031793(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0009416"(response to light stimulus)|go:"GO:0016020"(membrane)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417	ensembl:ENSSSCG00050030630(gene)|ensembl:ENSSSCG00055004566(gene)|ensembl:ENSSSCG00065057361(gene)|ensembl:ENSSSCT00050041186(transcript)|ensembl:ENSSSCT00055009021(transcript)|ensembl:ENSSSCT00065078518(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0010825"(positive regulation of centrosome duplication)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0046872"(metal ion binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0070168"(negative regulation of biomineral tissue development)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0072518"(Rho-dependent protein serine/threonine kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901888"(regulation of cell junction assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015008(Rho Binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020684|interpro:IPR037311|reactome:R-SSC-3928662|reactome:R-SSC-416482|reactome:R-SSC-4420097|reactome:R-SSC-5627117|reactome:R-SSC-8980692|reactome:R-SSC-9013026|reactome:R-SSC-9013106|reactome:R-SSC-9013407|reactome:R-SSC-9013422|reactome:R-SSC-416572	-	-	-	figure legend:Supp 6A|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9823(pig-retina-rod_outer_segment)|taxid:9823(Pig Rod Outer Segment)	-	2014/02/07	2020/01/08	rogid:SiGOVBLsD1pZ3qp3/OgAtFpWlmw9823	rogid:lzh/s1/BrQUygFX0627sOm+JVgs9823	intact-crc:67E7E20A89D54593|rigid:gvxRxsA12jjQIfn9rrPmTlvH87U	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)