#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
ensembl:ENSG00000182393	uniprotkb:P19838-PRO_0000030311	intact:EBI-10050274	intact:EBI-697771	uniprotkb:IFNL1(gene name)|psi-mi:IFNL1(display_short)|uniprotkb:IL29(gene name synonym)|uniprotkb:ZCYTO21(gene name synonym)|ensembl:ifnl1_human_gene(shortlabel)|psi-mi:ENSG00000182393(display_long)	psi-mi:p19838-pro_0000030311(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Siegel et al. (2011)	imex:IM-23655|pubmed:22058416	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10050276|imex:IM-23655-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	refseq:NP_742152.1	intact:EBI-300010(chain-parent)	-	-	chain-seq-start:1|chain-seq-end:433	figure legend:Fig. 2b|antagonist:"polyinosinic-polycytidylic acid (poly I:C), a TLR3 agonist"|causality statement:P19838-PRO_0000030311 decreases expression at RNA level of ENSG00000182393|causality statement:P19838-PRO_0000030311 decreases expression at protein level of ENSG00000182393|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-beas_2b)|taxid:9606(Human bronchial epithelial cell line BEAS-2B)	-	2014/12/30	2019/02/01	-	rogid:ZgJEP6sTCusv6e6HxIkMJ5Yuv1E9606	intact-crc:CE8960176FDE3A1B	false	binding-associated region:?-?|binding-associated region:?-?	-	-	-	psi-mi:"MI:1195"(quantitative pcr)	psi-mi:"MI:1195"(quantitative pcr)
ensembl:ENSG00000182393	uniprotkb:Q04864	intact:EBI-10050274	intact:EBI-307352|uniprotkb:Q2PNZ7|uniprotkb:Q6LDY0|ensembl:ENSP00000295025|intact:EBI-11133860|uniprotkb:Q17RU2	uniprotkb:IFNL1(gene name)|psi-mi:IFNL1(display_short)|uniprotkb:IL29(gene name synonym)|uniprotkb:ZCYTO21(gene name synonym)|ensembl:ifnl1_human_gene(shortlabel)|psi-mi:ENSG00000182393(display_long)	psi-mi:rel_human(display_long)|uniprotkb:REL(gene name)|psi-mi:REL(display_short)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Siegel et al. (2011)	imex:IM-23655|pubmed:22058416	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10050285|imex:IM-23655-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	refseq:NP_742152.1	refseq:NP_002899.1|ensembl:ENSG00000162924(gene)|ensembl:ENST00000295025(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034097"(response to cytokine)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030505|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|interpro:IPR042845|mint:Q04864|reactome:R-HSA-1169091|ensembl:ENSP00000295025|ensembl:ENST00000394479|ensembl:ENSP00000377989|refseq:NP_001278675.1|dip:DIP-301N	-	-	-	figure legend:Fig. 2c|agonist:"polyinosinic-polycytidylic acid (poly I:C), a TLR3 agonist"|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-beas_2b)|taxid:9606(Human bronchial epithelial cell line BEAS-2B)	-	2014/12/30	2019/02/01	-	rogid:pcMbZU8647eKKyub9wOL93NK6VE9606	intact-crc:625C863028D5BD50	false	binding-associated region:?-?|binding-associated region:?-?	-	-	-	psi-mi:"MI:1195"(quantitative pcr)	psi-mi:"MI:1195"(quantitative pcr)
ensembl:ENSG00000182393	uniprotkb:Q04206	intact:EBI-10050274	intact:EBI-73886|ensembl:ENSP00000384273|uniprotkb:Q6GTV1|uniprotkb:Q6SLK1	uniprotkb:IFNL1(gene name)|psi-mi:IFNL1(display_short)|uniprotkb:IL29(gene name synonym)|uniprotkb:ZCYTO21(gene name synonym)|ensembl:ifnl1_human_gene(shortlabel)|psi-mi:ENSG00000182393(display_long)	psi-mi:tf65_human(display_long)|uniprotkb:Nuclear factor NF-kappa-B p65 subunit(gene name synonym)|uniprotkb:RELA(gene name)|psi-mi:RELA(display_short)|uniprotkb:NFKB3(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Siegel et al. (2011)	imex:IM-23655|pubmed:22058416	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10050294|imex:IM-23655-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	refseq:NP_742152.1	ensembl:ENSG00000173039(gene)|ensembl:ENST00000406246(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|refseq:NP_001138610.1|refseq:NP_068810.3|refseq:NP_001230913.1|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0070301"(cellular response to hydrogen peroxide)|dip:DIP-24238N|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0001942"(hair follicle development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006117"(acetaldehyde metabolic process)|go:"GO:0006325"(chromatin organization)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0006968"(cellular defense response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010033"(response to organic substance)|go:"GO:0010224"(response to UV-B)|go:"GO:0014040"(positive regulation of Schwann cell differentiation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032570"(response to progesterone)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032868"(response to insulin)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0033590"(response to cobalamin)|go:"GO:0034097"(response to cytokine)|go:"GO:0035525"(NF-kappaB p50/p65 complex)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042277"(peptide binding)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042805"(actinin binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043200"(response to amino acid)|go:"GO:0043278"(response to morphine)|go:"GO:0043620"(regulation of DNA-templated transcription in response to stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051591"(response to cAMP)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0051607"(defense response to virus)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071223"(cellular response to lipoteichoic acid)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:2000630"(positive regulation of miRNA metabolic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030495|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|mint:Q04206|rcsb pdb:1NFI|rcsb pdb:2LSP|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:3QXY|rcsb pdb:3RC0|rcsb pdb:4KV1|rcsb pdb:4KV4|rcsb pdb:5U4K|rcsb pdb:5URN|rcsb pdb:6NV2|rcsb pdb:6QHL|rcsb pdb:6QHM|rcsb pdb:6YOW|rcsb pdb:6YOX|rcsb pdb:6YOY|rcsb pdb:6YP2|rcsb pdb:6YP3|rcsb pdb:6YP8|rcsb pdb:6YPL|rcsb pdb:6YPY|rcsb pdb:6YQ2|rcsb pdb:7BI3|rcsb pdb:7BIQ|rcsb pdb:7BIY|rcsb pdb:7BJF|rcsb pdb:7BJL|rcsb pdb:7BJW|rcsb pdb:7BKH|rcsb pdb:7NJ9|rcsb pdb:7NJB|rcsb pdb:7NK3|rcsb pdb:7NK5|rcsb pdb:7NLA|rcsb pdb:7NLE|rcsb pdb:7NM1|rcsb pdb:7NM3|rcsb pdb:7NM9|rcsb pdb:7NQP|rcsb pdb:7NR7|rcsb pdb:7NSV|rcsb pdb:7NV4|rcsb pdb:7NVI|rcsb pdb:7NWS|rcsb pdb:7NXS|rcsb pdb:7NXT|rcsb pdb:7NXW|rcsb pdb:7NXY|rcsb pdb:7NY4|rcsb pdb:7NYE|rcsb pdb:7NYF|rcsb pdb:7NYG|rcsb pdb:7NZ6|rcsb pdb:7NZG|rcsb pdb:7NZK|rcsb pdb:7NZV|rcsb pdb:7O34|rcsb pdb:7O3A|rcsb pdb:7O3F|rcsb pdb:7O3P|rcsb pdb:7O3Q|rcsb pdb:7O3R|rcsb pdb:7O3S|rcsb pdb:7O57|rcsb pdb:7O59|rcsb pdb:7O5A|rcsb pdb:7O5C|rcsb pdb:7O5D|rcsb pdb:7O5F|rcsb pdb:7O5G|rcsb pdb:7O5O|rcsb pdb:7O5P|rcsb pdb:7O5S|rcsb pdb:7O5U|rcsb pdb:7O5X|rcsb pdb:7O6F|rcsb pdb:7O6G|rcsb pdb:7O6I|rcsb pdb:7O6J|rcsb pdb:7O6K|rcsb pdb:7O6M|rcsb pdb:7O6O|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-4755510|reactome:R-HSA-5603029|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9660826	-	-	-	figure legend:Fig. 2d|agonist:"polyinosinic-polycytidylic acid (poly I:C), a TLR3 agonist"|causality statement:Q04206 increases expression at RNA level of ENSG00000182393|causality statement:Q04206 increases expression at protein level of ENSG00000182393|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-beas_2b)|taxid:9606(Human bronchial epithelial cell line BEAS-2B)	-	2014/12/30	2019/02/01	-	rogid:w/ClZ7PzdLH1LLxTGrk22KUz8V49606	intact-crc:01A587ACDBF7BC89	false	binding-associated region:?-?	-	-	-	psi-mi:"MI:1195"(quantitative pcr)	psi-mi:"MI:1195"(quantitative pcr)
ensembl:ENSG00000182393	uniprotkb:Q00653-PRO_0000030322	intact:EBI-10050274	intact:EBI-9869360	uniprotkb:IFNL1(gene name)|psi-mi:IFNL1(display_short)|uniprotkb:IL29(gene name synonym)|uniprotkb:ZCYTO21(gene name synonym)|ensembl:ifnl1_human_gene(shortlabel)|psi-mi:ENSG00000182393(display_long)	psi-mi:q00653-pro_0000030322(display_long)|uniprotkb:NFKB2(gene name)|psi-mi:NFKB2(display_short)|uniprotkb:LYT10(gene name synonym)|uniprotkb:DNA-binding factor KBF2(gene name synonym)|uniprotkb:H2TF1(gene name synonym)|uniprotkb:Lymphocyte translocation chromosome 10 protein(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2(gene name synonym)|uniprotkb:Oncogene Lyt-10(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Siegel et al. (2011)	imex:IM-23655|pubmed:22058416	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10050301|imex:IM-23655-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	refseq:NP_742152.1	intact:EBI-307326(chain-parent)	-	-	chain-seq-start:1|chain-seq-end:454	figure legend:Fig. 2e|agonist:"polyinosinic-polycytidylic acid (poly I:C), a TLR3 agonist"|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-beas_2b)|taxid:9606(Human bronchial epithelial cell line BEAS-2B)	-	2014/12/30	2019/02/01	-	rogid:lvqrZc2MPZn/04RK8xwZWBzHgjk9606	intact-crc:5EB7EF6F91B20433	false	binding-associated region:?-?	-	-	-	psi-mi:"MI:1195"(quantitative pcr)	psi-mi:"MI:1195"(quantitative pcr)
uniprotkb:P37275	ensembl:ENSG00000182393	intact:EBI-2849734|uniprotkb:Q12924|uniprotkb:Q5T968|uniprotkb:Q13800|uniprotkb:Q2KJ05|uniprotkb:B4DJV0|uniprotkb:B4DUW9|uniprotkb:E9PCM7|uniprotkb:F5H4I8|uniprotkb:Q5VZ84|uniprotkb:Q8NB68|intact:EBI-11153310|ensembl:ENSP00000319248	intact:EBI-10050274	psi-mi:zeb1_human(display_long)|uniprotkb:ZEB1(gene name)|psi-mi:ZEB1(display_short)|uniprotkb:AREB6(gene name synonym)|uniprotkb:TCF8(gene name synonym)|uniprotkb:NIL-2-A zinc finger protein(gene name synonym)|uniprotkb:Negative regulator of IL2(gene name synonym)|uniprotkb:Transcription factor 8(gene name synonym)	uniprotkb:IFNL1(gene name)|psi-mi:IFNL1(display_short)|uniprotkb:IL29(gene name synonym)|uniprotkb:ZCYTO21(gene name synonym)|ensembl:ifnl1_human_gene(shortlabel)|psi-mi:ENSG00000182393(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Siegel et al. (2011)	imex:IM-23655|pubmed:22058416	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10050308|imex:IM-23655-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_001121600.1|refseq:NP_001167565.1|refseq:NP_001167566.1|refseq:NP_110378.3|refseq:NP_001167564.1|refseq:NP_001167567.1|ensembl:ENSG00000148516(gene)|ensembl:ENST00000320985(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0045602"(negative regulation of endothelial cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048856"(anatomical structure development)|go:"GO:0070888"(E-box binding)|interpro:IPR001356(Homeobox)|interpro:IPR008598(Drought induced 19)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:2E19|reactome:R-HSA-6785807|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)	refseq:NP_742152.1	-	-	-	figure legend:Fig. 4c|antagonist:"polyinosinic-polycytidylic acid (poly I:C), a TLR3 agonist"|causality statement:P37275 decreases expression at RNA level of ENSG00000182393|causality statement:P37275 decreases expression at protein level of ENSG00000182393|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-beas_2b)|taxid:9606(Human bronchial epithelial cell line BEAS-2B)	-	2014/12/30	2019/02/01	rogid:2QwbT74tbgA6Jec85fGMRYg0EBI9606	-	intact-crc:3B27D86D95210DFD	false	-	binding-associated region:?-?	-	-	psi-mi:"MI:1195"(quantitative pcr)	psi-mi:"MI:1195"(quantitative pcr)
ensembl:ENSG00000182393	uniprotkb:O75626	intact:EBI-10050274	intact:EBI-948789|ensembl:ENSP00000358092|uniprotkb:B2REA6|uniprotkb:E1P5E0|uniprotkb:Q86WM7	uniprotkb:IFNL1(gene name)|psi-mi:IFNL1(display_short)|uniprotkb:IL29(gene name synonym)|uniprotkb:ZCYTO21(gene name synonym)|ensembl:ifnl1_human_gene(shortlabel)|psi-mi:ENSG00000182393(display_long)	psi-mi:prdm1_human(display_long)|uniprotkb:PR domain-containing protein 1(gene name synonym)|uniprotkb:Beta-interferon gene positive regulatory domain I-binding factor(gene name synonym)|uniprotkb:BLIMP-1(gene name synonym)|uniprotkb:Positive regulatory domain I-binding factor 1(gene name synonym)|uniprotkb:PRDM1(gene name)|psi-mi:PRDM1(display_short)|uniprotkb:BLIMP1(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Siegel et al. (2011)	imex:IM-23655|pubmed:22058416	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10050315|imex:IM-23655-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	refseq:NP_742152.1	ensembl:ENSG00000057657(gene)|ensembl:ENST00000369096(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001763"(morphogenesis of a branching structure)|go:"GO:0001822"(kidney development)|go:"GO:0001893"(maternal placenta development)|go:"GO:0002250"(adaptive immune response)|go:"GO:0003170"(heart valve development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007281"(germ cell development)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0009791"(post-embryonic development)|interpro:IPR044413|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0032259"(methylation)|go:"GO:0032823"(regulation of natural killer cell differentiation)|go:"GO:0033082"(regulation of extrathymic T cell differentiation)|go:"GO:0035904"(aorta development)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0051136"(regulation of NK T cell differentiation)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060976"(coronary vasculature development)|go:"GO:1990654"(sebum secreting cell proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR016608(PR-domain zinc finger protein PRDM1)|interpro:IPR036236|rcsb pdb:3DAL|reactome:R-HSA-6804754|mint:O75626|refseq:XP_016866676.1|refseq:NP_001189.2|refseq:XP_011534365.1|refseq:NP_878911.1	-	-	-	figure legend:Fig. 6a|causality statement:O75626 decreases expression at RNA level of ENSG00000182393|causality statement:O75626 decreases expression at protein level of ENSG00000182393|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-beas_2b)|taxid:9606(Human bronchial epithelial cell line BEAS-2B)	-	2014/12/30	2019/02/01	-	rogid:Wc1HnBei0Xhkps6Wf65Gjc3nllw9606	intact-crc:02B3397076C6C502	false	binding-associated region:?-?|binding-associated region:?-?	-	-	-	psi-mi:"MI:1195"(quantitative pcr)	psi-mi:"MI:1195"(quantitative pcr)
uniprotkb:P10914	ensembl:ENSG00000182393	intact:EBI-1055781|uniprotkb:Q96GG7|ensembl:ENSP00000245414|ensembl:ENSP00000384406	intact:EBI-10050274	psi-mi:irf1_human(display_long)|uniprotkb:IRF1(gene name)|psi-mi:IRF1(display_short)	uniprotkb:IFNL1(gene name)|psi-mi:IFNL1(display_short)|uniprotkb:IL29(gene name synonym)|uniprotkb:ZCYTO21(gene name synonym)|ensembl:ifnl1_human_gene(shortlabel)|psi-mi:ENSG00000182393(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Siegel et al. (2011)	imex:IM-23655|pubmed:22058416	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10050323|imex:IM-23655-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_002189.1|ensembl:ENSG00000125347(gene)|ensembl:ENST00000245414(transcript)|ensembl:ENST00000405885(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0034124"(regulation of MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043374"(CD8-positive, alpha-beta T cell differentiation)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045590"(negative regulation of regulatory T cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:2000564"(regulation of CD8-positive, alpha-beta T cell proliferation)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031215|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231|dip:DIP-40988N	refseq:NP_742152.1	-	-	-	figure legend:Fig. 6b|agonist:"polyinosinic-polycytidylic acid (poly I:C), a TLR3 agonist"|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-beas_2b)|taxid:9606(Human bronchial epithelial cell line BEAS-2B)	-	2014/12/30	2019/02/01	rogid:ToPrN31Dt6/EQuaX8gkxFBDJp5Q9606	-	intact-crc:A70DBB69C123411A	false	-	binding-associated region:?-?|binding-associated region:?-?	-	-	psi-mi:"MI:1195"(quantitative pcr)	psi-mi:"MI:1195"(quantitative pcr)