#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9Y271	uniprotkb:Q9NS75	intact:EBI-9347754|uniprotkb:B2R954|uniprotkb:D3DTE4|uniprotkb:Q5JS94|uniprotkb:Q8IV19|ensembl:ENSP00000362401|ensembl:ENSP00000478492	intact:EBI-3843579|uniprotkb:Q9HCQ2|ensembl:ENSP00000282018|ensembl:ENSP00000477930|ensembl:ENSP00000508181	psi-mi:cltr1_human(display_long)|uniprotkb:CYSLTR1(gene name)|psi-mi:CYSLTR1(display_short)|uniprotkb:CYSLT1(gene name synonym)|uniprotkb:Cysteinyl leukotriene D4 receptor(gene name synonym)|uniprotkb:G-protein coupled receptor HG55(gene name synonym)|uniprotkb:HMTMF81(gene name synonym)	psi-mi:cltr2_human(display_long)|uniprotkb:CYSLTR2(gene name)|psi-mi:CYSLTR2(display_short)|uniprotkb:CYSLT2(gene name synonym)|uniprotkb:CYSLT2R(gene name synonym)|uniprotkb:G-protein coupled receptor GPCR21(gene name synonym)|uniprotkb:G-protein coupled receptor HG57(gene name synonym)|uniprotkb:HPN321(gene name synonym)|uniprotkb:PSEC0146(orf name)	psi-mi:"MI:0813"(proximity ligation assay)	Parhamifar et al. (2010)	pubmed:21203429|imex:IM-22304	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9347752|imex:IM-22304-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001269115.1|refseq:NP_001269116.1|refseq:NP_001269117.1|refseq:NP_006630.1|ensembl:ENSG00000173198(gene)|ensembl:ENST00000373304(transcript)|ensembl:ENST00000614798(transcript)|go:"GO:0001631"(cysteinyl leukotriene receptor activity)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0004974"(leukotriene receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006935"(chemotaxis)|go:"GO:0006952"(defense response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008528"(G protein-coupled peptide receptor activity)|go:"GO:0016020"(membrane)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR004071(Cysteinyl leukotriene receptor)|interpro:IPR013310(Cysteinyl leukotriene receptor 1)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6RZ4|rcsb pdb:6RZ5|reactome:R-HSA-391906|reactome:R-HSA-416476|reactome:R-HSA-9664535|reactome:R-HSA-9679191	refseq:NP_001295394.1|refseq:NP_001295396.1|refseq:NP_001295397.1|refseq:NP_001295398.1|refseq:NP_001295399.1|refseq:NP_001295400.1|refseq:NP_001295405.1|refseq:NP_065110.1|ensembl:ENSG00000152207(gene)|ensembl:ENST00000282018(transcript)|ensembl:ENST00000614739(transcript)|ensembl:ENST00000682523(transcript)|go:"GO:0001631"(cysteinyl leukotriene receptor activity)|go:"GO:0004974"(leukotriene receptor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0008528"(G protein-coupled peptide receptor activity)|go:"GO:0071377"(cellular response to glucagon stimulus)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR004071(Cysteinyl leukotriene receptor)|interpro:IPR013311(Cysteinyl leukotriene receptor 2)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:Q9NS75|reactome:R-HSA-163359|reactome:R-HSA-391906|reactome:R-HSA-416476|reactome:R-HSA-418555|reactome:R-HSA-420092|reactome:R-HSA-9660821|reactome:R-HSA-9664535	go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)	-	-	figure legend:1A|comment:"Five minutes after LTD4 (Leukotriene D4) addition a  deccrease in receptor heterodimerization  was observed;however after 60 minutes of LTD4 stimulation, a slight increase in heterodimerization compared to the 5 minutes value was observed.  Genistein  reduced this increase."|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/04/02	2014/10/16	rogid:UJJYInXv7/5NyggyGbyztWqcZTM9606	rogid:NRzlafGrSL5F5/uRRFJrMXrEsEc9606	intact-crc:7825ADFB0AF4AC70|rigid:hQJdh5jdY0HymynSCOSfXdTVBlQ	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:Q9NS75	uniprotkb:Q9Y271	intact:EBI-3843579|uniprotkb:Q9HCQ2|ensembl:ENSP00000282018|ensembl:ENSP00000477930|ensembl:ENSP00000508181	intact:EBI-9347754|uniprotkb:B2R954|uniprotkb:D3DTE4|uniprotkb:Q5JS94|uniprotkb:Q8IV19|ensembl:ENSP00000362401|ensembl:ENSP00000478492	psi-mi:cltr2_human(display_long)|uniprotkb:CYSLTR2(gene name)|psi-mi:CYSLTR2(display_short)|uniprotkb:CYSLT2(gene name synonym)|uniprotkb:CYSLT2R(gene name synonym)|uniprotkb:G-protein coupled receptor GPCR21(gene name synonym)|uniprotkb:G-protein coupled receptor HG57(gene name synonym)|uniprotkb:HPN321(gene name synonym)|uniprotkb:PSEC0146(orf name)	psi-mi:cltr1_human(display_long)|uniprotkb:CYSLTR1(gene name)|psi-mi:CYSLTR1(display_short)|uniprotkb:CYSLT1(gene name synonym)|uniprotkb:Cysteinyl leukotriene D4 receptor(gene name synonym)|uniprotkb:G-protein coupled receptor HG55(gene name synonym)|uniprotkb:HMTMF81(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Parhamifar et al. (2010)	pubmed:21203429|imex:IM-22304	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9347833|imex:IM-22304-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001295394.1|refseq:NP_001295396.1|refseq:NP_001295397.1|refseq:NP_001295398.1|refseq:NP_001295399.1|refseq:NP_001295400.1|refseq:NP_001295405.1|refseq:NP_065110.1|ensembl:ENSG00000152207(gene)|ensembl:ENST00000282018(transcript)|ensembl:ENST00000614739(transcript)|ensembl:ENST00000682523(transcript)|go:"GO:0001631"(cysteinyl leukotriene receptor activity)|go:"GO:0004974"(leukotriene receptor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0008528"(G protein-coupled peptide receptor activity)|go:"GO:0071377"(cellular response to glucagon stimulus)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR004071(Cysteinyl leukotriene receptor)|interpro:IPR013311(Cysteinyl leukotriene receptor 2)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:Q9NS75|reactome:R-HSA-163359|reactome:R-HSA-391906|reactome:R-HSA-416476|reactome:R-HSA-418555|reactome:R-HSA-420092|reactome:R-HSA-9660821|reactome:R-HSA-9664535	refseq:NP_001269115.1|refseq:NP_001269116.1|refseq:NP_001269117.1|refseq:NP_006630.1|ensembl:ENSG00000173198(gene)|ensembl:ENST00000373304(transcript)|ensembl:ENST00000614798(transcript)|go:"GO:0001631"(cysteinyl leukotriene receptor activity)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0004974"(leukotriene receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006935"(chemotaxis)|go:"GO:0006952"(defense response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008528"(G protein-coupled peptide receptor activity)|go:"GO:0016020"(membrane)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR004071(Cysteinyl leukotriene receptor)|interpro:IPR013310(Cysteinyl leukotriene receptor 1)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6RZ4|rcsb pdb:6RZ5|reactome:R-HSA-391906|reactome:R-HSA-416476|reactome:R-HSA-9664535|reactome:R-HSA-9679191	-	-	-	figure legend:Supp 1|antagonist:LD4-Leukotriene D4|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells)	-	2014/04/02	2014/10/16	rogid:NRzlafGrSL5F5/uRRFJrMXrEsEc9606	rogid:UJJYInXv7/5NyggyGbyztWqcZTM9606	intact-crc:AD9004C3A19552DC|rigid:hQJdh5jdY0HymynSCOSfXdTVBlQ	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)