#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9WMX2-PRO_0000037550 uniprotkb:P08962 intact:EBI-8853273 intact:EBI-762053|uniprotkb:Q5TZP3|uniprotkb:Q9UCG6|uniprotkb:Q8N6Z9|uniprotkb:F8VZE2|ensembl:ENSP00000257857|ensembl:ENSP00000393502|ensembl:ENSP00000447730|ensembl:ENSP00000449337 psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:cd63_human(display_long)|uniprotkb:Melanoma-associated antigen ME491(gene name synonym)|uniprotkb:Ocular melanoma-associated antigen(gene name synonym)|uniprotkb:OMA81H(gene name synonym)|uniprotkb:Granulophysin(gene name synonym)|uniprotkb:Tetraspanin-30(gene name synonym)|uniprotkb:Lysosomal-associated membrane protein 3(gene name synonym)|uniprotkb:CD63(gene name)|psi-mi:CD63(display_short)|uniprotkb:MLA1(gene name synonym)|uniprotkb:TSPAN30(gene name synonym)|uniprotkb:Lysosome integral membrane protein 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083739|imex:IM-26075-99 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-710918(chain-parent) refseq:NP_001771.1|refseq:NP_001244330.1|refseq:NP_001244318.1|refseq:NP_001244319.1|refseq:NP_001244320.1|refseq:NP_001244329.1|refseq:NP_001254627.1|refseq:NP_001244321.1|ensembl:ENSG00000135404(gene)|ensembl:ENST00000257857(transcript)|go:"GO:1900746"(regulation of vascular endothelial growth factor signaling pathway)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|interpro:IPR000301(CD9/CD37/CD63 antigen)|interpro:IPR008952(Tetraspanin)|interpro:IPR018499|interpro:IPR018503|interpro:IPR042028|mint:P08962|reactome:R-HSA-114608|reactome:R-HSA-6798695|go:"GO:0097487"(multivesicular body, internal vesicle)|ensembl:ENST00000420846(transcript)|ensembl:ENST00000549117(transcript)|ensembl:ENST00000552692(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016477"(cell migration)|go:"GO:0031088"(platelet dense granule membrane)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031904"(endosome lumen)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0042470"(melanosome)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048757"(pigment granule maturation)|go:"GO:0070062"(extracellular exosome) - chain-seq-start:1712|chain-seq-end:1972 - figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 rogid:stCGi5kkTMIdO84qSwjmjpUwwvs9606 intact-crc:1046E5D19F539685|rigid:Qpey4hIETFfvTdBvOItj3IAZsJM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15485 uniprotkb:Q9WMX2-PRO_0000037550 intact:EBI-7468784|uniprotkb:A6NFG7|uniprotkb:Q9UC57|uniprotkb:Q6IS69|intact:MINT-5223224|uniprotkb:Q7M4P4|uniprotkb:A8K478|ensembl:ENSP00000291744 intact:EBI-8853273 psi-mi:fcn2_human(display_long)|uniprotkb:FCN2(gene name)|psi-mi:FCN2(display_short)|uniprotkb:FCNL(gene name synonym)|uniprotkb:Ficolin-B(gene name synonym)|uniprotkb:Ficolin-beta(gene name synonym)|uniprotkb:L-ficolin(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 2(gene name synonym)|uniprotkb:Serum lectin p35(gene name synonym)|uniprotkb:37 kDa elastin-binding protein(gene name synonym)|uniprotkb:EBP-37(gene name synonym)|uniprotkb:Hucolin(gene name synonym) psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083586|imex:IM-26075-103 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004099.2|refseq:NP_056652.1|ensembl:ENSG00000160339(gene)|ensembl:ENST00000291744(transcript)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0003823"(antigen binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0008228"(opsonization)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0043654"(recognition of apoptotic cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0097367"(carbohydrate derivative binding)|go:"GO:2001065"(mannan binding)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|mint:Q15485|rcsb pdb:2J0G|rcsb pdb:2J0H|rcsb pdb:2J0Y|rcsb pdb:2J1G|rcsb pdb:2J2P|rcsb pdb:2J3F|rcsb pdb:2J3G|rcsb pdb:2J3O|rcsb pdb:2J3U|rcsb pdb:2J61|rcsb pdb:4NYT|rcsb pdb:4R9J|rcsb pdb:4R9T|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-2855086 intact:EBI-710918(chain-parent) - comment:mint|function:Calcium-dependent and GlcNAc-binding lectin. Enhanced phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect via the collagen region chain-seq-start:1712|chain-seq-end:1972 figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:j6vRtYG3I6cn0c2TId/73bE/1To9606 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 intact-crc:815C055200A48528|rigid:Pf8sUG8da/EF9oOwfzLtVqMJIx0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9WMX2-PRO_0000037550 uniprotkb:P02753 intact:EBI-8853273 intact:EBI-2116134|uniprotkb:O43478|uniprotkb:O43479|uniprotkb:Q5VY24|uniprotkb:Q8WWA3|uniprotkb:Q9P178|uniprotkb:D3DR38|ensembl:ENSP00000360519|ensembl:ENSP00000360522 psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:ret4_human(display_long)|uniprotkb:RBP4(gene name)|psi-mi:RBP4(display_short)|uniprotkb:Plasma retinol-binding protein(gene name synonym)|uniprotkb:PRO2222(orf name) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083711|imex:IM-26075-111 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-710918(chain-parent) refseq:NP_006735.2|refseq:NP_001310446.1|refseq:NP_001310447.1|ensembl:ENSG00000138207(gene)|ensembl:ENST00000371464(transcript)|ensembl:ENST00000371467(transcript)|go:"GO:0001654"(eye development)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0007507"(heart development)|go:"GO:0007601"(visual perception)|go:"GO:0016918"(retinal binding)|go:"GO:0019841"(retinol binding)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0030324"(lung development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034632"(retinol transmembrane transporter activity)|go:"GO:0034633"(retinol transport)|go:"GO:0042572"(retinol metabolic process)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0048562"(embryonic organ morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0048807"(female genitalia morphogenesis)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060059"(embryonic retina morphogenesis in camera-type eye)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060157"(urinary bladder development)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR002449(Retinol-binding protein)|interpro:IPR012674(Calycin)|interpro:IPR022271|interpro:IPR022272|rcsb pdb:1BRP|rcsb pdb:1BRQ|rcsb pdb:1JYD|rcsb pdb:1JYJ|rcsb pdb:1QAB|rcsb pdb:1RBP|rcsb pdb:1RLB|rcsb pdb:2WQ9|rcsb pdb:2WQA|rcsb pdb:2WR6|rcsb pdb:3BSZ|rcsb pdb:3FMZ|rcsb pdb:4O9S|rcsb pdb:4PSQ|rcsb pdb:5NTY|rcsb pdb:5NU2|rcsb pdb:5NU6|rcsb pdb:5NU7|rcsb pdb:5NU8|rcsb pdb:5NU9|rcsb pdb:5NUA|rcsb pdb:5NUB|rcsb pdb:6QBA|reactome:R-HSA-2453864|reactome:R-HSA-2453902|reactome:R-HSA-6809583|reactome:R-HSA-975634 - chain-seq-start:1712|chain-seq-end:1972 - figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 rogid:2vaCDK/IuJXaETBv+YotwdHkIsY9606 intact-crc:A2682C146284FE8D|rigid:Nt93RphTPsLqGNqrcmpKXWrM5cE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9WMX2-PRO_0000037550 uniprotkb:P81172 intact:EBI-8853273 intact:EBI-3942179|uniprotkb:Q1HE14|uniprotkb:Q9BY68|ensembl:ENSP00000222304|ensembl:ENSP00000471894 psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:hepc_human(display_long)|uniprotkb:HAMP(gene name)|psi-mi:HAMP(display_short)|uniprotkb:HEPC(gene name synonym)|uniprotkb:LEAP1(gene name synonym)|uniprotkb:Liver-expressed antimicrobial peptide 1(gene name synonym)|uniprotkb:Putative liver tumor regressor(gene name synonym)|uniprotkb:UNQ487/PRO1003(orf name) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083707|imex:IM-26075-39 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-710918(chain-parent) ensembl:ENSG00000105697(gene)|ensembl:ENST00000222304(transcript)|ensembl:ENST00000598398(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0002262"(myeloid cell homeostasis)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005179"(hormone activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006953"(acute-phase response)|go:"GO:0006955"(immune response)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007568"(aging)|go:"GO:0010039"(response to iron ion)|go:"GO:0010043"(response to zinc ion)|go:"GO:0014704"(intercalated disc)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0032413"(negative regulation of ion transmembrane transporter activity)|go:"GO:0033189"(response to vitamin A)|go:"GO:0034760"(negative regulation of iron ion transmembrane transport)|go:"GO:0036017"(response to erythropoietin)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0045179"(apical cortex)|go:"GO:0045471"(response to ethanol)|go:"GO:0045779"(negative regulation of bone resorption)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0060586"(multicellular organismal iron ion homeostasis)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0097421"(liver regeneration)|go:"GO:0097690"(iron ion transmembrane transporter inhibitor activity)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903413"(cellular response to bile acid)|go:"GO:1904039"(negative regulation of iron export across plasma membrane)|go:"GO:1904255"(negative regulation of iron ion transmembrane transporter activity)|go:"GO:1904479"(negative regulation of intestinal absorption)|go:"GO:1990641"(response to iron ion starvation)|go:"GO:2000646"(positive regulation of receptor catabolic process)|interpro:IPR010500(Hepcidin)|rcsb pdb:1M4E|rcsb pdb:1M4F|rcsb pdb:2KEF|rcsb pdb:3H0T|rcsb pdb:4QAE|rcsb pdb:6WBV|refseq:NP_066998.1 - chain-seq-start:1712|chain-seq-end:1972 - figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 rogid:7lw0t4rz5e7eyJBW8A8RoT1OcoI9606 intact-crc:31A27BB52B1D2FB9|rigid:0gybz5FyI7JbijmV4GBTAe2+8Io false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9WMX2-PRO_0000037550 uniprotkb:Q9NPA0 intact:EBI-8853273 intact:EBI-6309137|ensembl:ENSP00000256545|uniprotkb:B2RC00|uniprotkb:Q96ED5 psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:emc7_human(display_long)|uniprotkb:EMC7(gene name)|psi-mi:EMC7(display_short)|uniprotkb:C11orf3(gene name synonym)|uniprotkb:C15orf24(gene name synonym)|uniprotkb:HT022(orf name)|uniprotkb:UNQ905/PRO1926(orf name) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083703|imex:IM-26075-97 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-710918(chain-parent) ensembl:ENSG00000134153(gene)|ensembl:ENST00000256545(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR019008|interpro:IPR039163|rcsb pdb:1B0G|rcsb pdb:1LP9|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2UWE|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|refseq:NP_064539.1 - chain-seq-start:1712|chain-seq-end:1972 - figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 rogid:XBg97fKNpvbssNf6YFewsWDmiBE9606 intact-crc:E78894D23894015B|rigid:BvaFQbvsokFJ9cInIVXNXkfFCVQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P22309 uniprotkb:Q9WMX2-PRO_0000037550 intact:EBI-3940292|ensembl:ENSP00000304845|uniprotkb:A6NJC3|uniprotkb:B8K286 intact:EBI-8853273 psi-mi:ud11_human(display_long)|uniprotkb:UGT1A1(gene name)|psi-mi:UGT1A1(display_short)|uniprotkb:GNT1(gene name synonym)|uniprotkb:UGT1(gene name synonym)|uniprotkb:Bilirubin-specific UDPGT isozyme 1(gene name synonym)|uniprotkb:UDP-glucuronosyltransferase 1-1(gene name synonym)|uniprotkb:UDP-glucuronosyltransferase 1A isoform 1(gene name synonym) psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083684|imex:IM-26075-77 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000241635(gene)|ensembl:ENST00000305208(transcript)|go:"GO:0001889"(liver development)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006789"(bilirubin conjugation)|go:"GO:0006953"(acute-phase response)|go:"GO:0007584"(response to nutrient)|go:"GO:0008202"(steroid metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0015020"(glucuronosyltransferase activity)|go:"GO:0017144"|go:"GO:0019899"(enzyme binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0042493"|go:"GO:0042573"(retinoic acid metabolic process)|go:"GO:0042594"(response to starvation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045922"(negative regulation of fatty acid metabolic process)|go:"GO:0045939"(negative regulation of steroid metabolic process)|go:"GO:0046483"(heterocycle metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051552"(flavone metabolic process)|go:"GO:0052695"(cellular glucuronidation)|go:"GO:0052696"(flavonoid glucuronidation)|go:"GO:0052697"(xenobiotic glucuronidation)|go:"GO:0070069"(cytochrome complex)|go:"GO:0070980"(biphenyl catabolic process)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:1904224"(negative regulation of glucuronosyltransferase activity)|go:"GO:2001030"(negative regulation of cellular glucuronidation)|interpro:IPR002213(UDP-glucuronosyl/UDP-glucosyltransferase)|interpro:IPR035595|reactome:R-HSA-156588|reactome:R-HSA-189483|reactome:R-HSA-5579002|go:"GO:0005789"(endoplasmic reticulum membrane)|refseq:NP_000454.1 intact:EBI-710918(chain-parent) - - chain-seq-start:1712|chain-seq-end:1972 figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:9KZMYxCe3FA4iSEOUErd2j9ds1w9606 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 intact-crc:00589D3F50CF6C60|rigid:f9BLldbz0f02JzyT3aAQOpevZ60 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q04941 uniprotkb:Q9WMX2-PRO_0000037550 intact:EBI-608347|ensembl:ENSP00000365505|uniprotkb:A6NDT7|uniprotkb:Q32MM8 intact:EBI-8853273 psi-mi:plp2_human(display_long)|uniprotkb:Intestinal membrane A4 protein(gene name synonym)|uniprotkb:Differentiation-dependent protein A4(gene name synonym)|uniprotkb:PLP2(gene name)|psi-mi:PLP2(display_short)|uniprotkb:A4(gene name synonym) psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083666|imex:IM-26075-95 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000102007(gene)|ensembl:ENST00000376327(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0006935"(chemotaxis)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019956"(chemokine binding)|interpro:IPR008253(Marvel)|refseq:NP_002659.1 intact:EBI-710918(chain-parent) - - chain-seq-start:1712|chain-seq-end:1972 figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:mQOlRVDVw9W4XWAzftif1tnKEdU9606 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 intact-crc:3674E57244356486|rigid:anAC24f9vnJ/zigBAMtDR1pG4BI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9HC24 uniprotkb:Q9WMX2-PRO_0000037550 intact:EBI-1045545|uniprotkb:Q9UHY5|uniprotkb:Q9Y3C2|uniprotkb:Q542Z6|ensembl:ENSP00000350965 intact:EBI-8853273 psi-mi:lfg4_human(display_long)|uniprotkb:Z-protein(gene name synonym)|uniprotkb:Protein S1R(gene name synonym)|uniprotkb:TMBIM4(gene name)|psi-mi:TMBIM4(display_short)|uniprotkb:CGI-119(orf name)|uniprotkb:GAAP(gene name synonym)|uniprotkb:Golgi anti-apoptotic protein(gene name synonym)|uniprotkb:LFG4(gene name synonym)|uniprotkb:Transmembrane BAX inhibitor motif-containing protein 4(gene name synonym) psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083657|imex:IM-26075-35 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001269535.1|refseq:NP_001269538.1|refseq:NP_001269539.1|ensembl:ENSG00000155957(gene)|ensembl:ENST00000358230(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005795"(Golgi stack)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0050848"(regulation of calcium-mediated signaling)|interpro:IPR006214(Protein of unknown function UPF0005)|refseq:NP_057140.2 intact:EBI-710918(chain-parent) - - chain-seq-start:1712|chain-seq-end:1972 figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:zkmPM2HoLpytHcy47b+gKBrEbN09606 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 intact-crc:D3637E96EB8DC4AB|rigid:NBO6e+bifriKHTXd+Cre11Dda70 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Y320 uniprotkb:Q9WMX2-PRO_0000037550 intact:EBI-6447886|ensembl:ENSP00000278422|uniprotkb:B7Z4R4|uniprotkb:Q8NBP9|uniprotkb:Q5J7Q7|uniprotkb:Q561W0|uniprotkb:Q53G73|uniprotkb:Q9H3L1|intact:EBI-7128726|intact:MINT-6945923 intact:EBI-8853273 psi-mi:tmx2_human(display_long)|uniprotkb:Cell proliferation-inducing gene 26 protein(gene name synonym)|uniprotkb:TXNDC14(gene name synonym)|uniprotkb:Thioredoxin domain-containing protein 14(gene name synonym)|uniprotkb:CGI-31(orf name)|uniprotkb:My009(orf name)|uniprotkb:PIG26(orf name)|uniprotkb:PSEC0045(orf name)|uniprotkb:UNQ237/PRO270(orf name)|uniprotkb:TMX2(gene name)|psi-mi:TMX2(display_short) psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083652|imex:IM-26075-93 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000213593(gene)|ensembl:ENST00000278422(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007420"(brain development)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043227"(membrane-bounded organelle)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR037463|interpro:IPR039101|mint:Q9Y320|rcsb pdb:2DJ0|refseq:NP_001137484.1|refseq:NP_057043.1 intact:EBI-710918(chain-parent) - - chain-seq-start:1712|chain-seq-end:1972 figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:5YbR806GhogQ2yI3r9uo8i97MzY9606 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 intact-crc:DB20DDD048ECC6C2|rigid:SNO0Mlsc89ZwwXpevchjBjv+HOw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9WMX2-PRO_0000037550 uniprotkb:P03905 intact:EBI-8853273 intact:EBI-1246274|uniprotkb:Q6RL39|uniprotkb:Q6RQN9|uniprotkb:Q8HNR8|ensembl:ENSP00000354961 psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:nu4m_human(display_long)|uniprotkb:MT-ND4(gene name)|psi-mi:MT-ND4(display_short)|uniprotkb:MTND4(gene name synonym)|uniprotkb:NADH4(gene name synonym)|uniprotkb:ND4(gene name synonym)|uniprotkb:NADH dehydrogenase subunit 4(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083644|imex:IM-26075-33 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-710918(chain-parent) refseq:YP_003024035.1|ensembl:ENSG00000198886(gene)|ensembl:ENST00000361381(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007568"(aging)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0021549"(cerebellum development)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035094"(response to nicotine)|go:"GO:0045471"(response to ethanol)|go:"GO:0048039"(ubiquinone binding)|interpro:IPR000260(NADH-ubiquinone oxidoreductase chain 4, N-terminal)|interpro:IPR001750("NADH/Ubiquinone/plastoquinone (complex I)")|interpro:IPR003918(NADH-ubiquinone oxidoreductase, chain 4)|interpro:IPR010227(Proton-translocating NADH-quinone oxidoreductase, chain M)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - chain-seq-start:1712|chain-seq-end:1972 - figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 rogid:O+b63kRTlmPDBdo6Oe90fRomfeY9606 intact-crc:A35AF7FBAC22BA00|rigid:Joa5ffzcAh2ILmKUX4nKbd1aPzE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9WMX2-PRO_0000037550 uniprotkb:P35354 intact:EBI-8853273 intact:EBI-6662113|ensembl:ENSP00000356438|ensembl:ENSP00000506242|uniprotkb:A8K802|uniprotkb:Q16876 psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:pgh2_human(display_long)|uniprotkb:PTGS2(gene name)|psi-mi:PTGS2(display_short)|uniprotkb:COX2(gene name synonym)|uniprotkb:Cyclooxygenase-2(gene name synonym)|uniprotkb:PHS II(gene name synonym)|uniprotkb:Prostaglandin H2 synthase 2(gene name synonym)|uniprotkb:Prostaglandin-endoperoxide synthase 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083640|imex:IM-26075-91 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-710918(chain-parent) ensembl:ENSG00000073756(gene)|ensembl:ENST00000367468(transcript)|ensembl:ENST00000680451(transcript)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001525"(angiogenesis)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004666"(prostaglandin-endoperoxide synthase activity)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005901"(caveola)|go:"GO:0006954"(inflammatory response)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007566"(embryo implantation)|go:"GO:0016702"(oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019371"(cyclooxygenase pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0020037"(heme binding)|go:"GO:0030282"(bone mineralization)|go:"GO:0007568"(aging)|go:"GO:0007612"(learning)|go:"GO:0030728"(ovulation)|go:"GO:0007613"(memory)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0031622"(positive regulation of fever generation)|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0032227"(negative regulation of synaptic transmission, dopaminergic)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0033280"(response to vitamin D)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042493"|go:"GO:0042633"(hair cycle)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0009750"(response to fructose)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0010042"(response to manganese ion)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0010226"(response to lithium ion)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045986"(negative regulation of smooth muscle contraction)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0046697"(decidualization)|go:"GO:0046872"(metal ion binding)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0090362"(positive regulation of platelet-derived growth factor production)|go:"GO:0150077"(regulation of neuroinflammatory response)|go:"GO:1902219"(negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress)|go:"GO:1990776"(response to angiotensin)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR010255(Haem peroxidase)|interpro:IPR019791|interpro:IPR029576|interpro:IPR037120|rcsb pdb:1V0X|rcsb pdb:5F19|rcsb pdb:5F1A|rcsb pdb:5IKQ|rcsb pdb:5IKR|go:"GO:0070542"(response to fatty acid)|rcsb pdb:5IKT|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071284"(cellular response to lead ion)|rcsb pdb:5IKV|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071456"(cellular response to hypoxia)|rcsb pdb:5KIR|reactome:R-HSA-197264|reactome:R-HSA-2142770|go:"GO:0071471"(cellular response to non-ionic osmotic stress)|reactome:R-HSA-2162123|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0071636"(positive regulation of transforming growth factor beta production)|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-9018677|reactome:R-HSA-9018679|reactome:R-HSA-9025094|reactome:R-HSA-9027604|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090271"(positive regulation of fibroblast growth factor production)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|refseq:NP_000954.1|dip:DIP-28131N - chain-seq-start:1712|chain-seq-end:1972 - figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 rogid:WGHtPKMIVOhbG4HdzQyqaBTUH509606 intact-crc:55C6EC9C1ECA7914|rigid:QJ+NY5Mb4AuDn48/wRBccUamJTQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14209 uniprotkb:Q9WMX2-PRO_0000037550 intact:EBI-748547|uniprotkb:O00518|uniprotkb:Q6ICV7|uniprotkb:A6NIW1|ensembl:ENSP00000370588 intact:EBI-8853273 psi-mi:cd99_human(display_long)|uniprotkb:T-cell surface glycoprotein E2(gene name synonym)|uniprotkb:E2 antigen(gene name synonym)|uniprotkb:Protein MIC2(gene name synonym)|uniprotkb:12E7(gene name synonym)|uniprotkb:CD99(gene name)|psi-mi:CD99(display_short)|uniprotkb:MIC2(gene name synonym)|uniprotkb:MIC2X(gene name synonym)|uniprotkb:MIC2Y(gene name synonym) psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083636|imex:IM-26075-75 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116370.1|refseq:NP_002405.1|refseq:NP_001308296.1|refseq:NP_001308297.1|refseq:NP_001308298.1|ensembl:ENSG00000002586(gene)|ensembl:ENST00000381192(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0034109"(homotypic cell-cell adhesion)|go:"GO:0072683"(T cell extravasation)|go:"GO:2000391"(positive regulation of neutrophil extravasation)|interpro:IPR022078|reactome:R-HSA-198933|reactome:R-HSA-202733 intact:EBI-710918(chain-parent) - - chain-seq-start:1712|chain-seq-end:1972 figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:g0uUrvPtgp5eBwP7RXnQa0Ij6GU9606 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 intact-crc:1CA1E4C2CDB76CF5|rigid:iXyQ5dnBmP/eCIOkoJfNe6rI9pI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P27701 uniprotkb:Q9WMX2-PRO_0000037550 intact:EBI-682379|uniprotkb:Q7Z2D4|uniprotkb:D3DQN6|intact:EBI-726186|uniprotkb:E9PC70|uniprotkb:Q7Z5N2|ensembl:ENSP00000227155 intact:EBI-8853273 psi-mi:cd82_human(display_long)|uniprotkb:Inducible membrane protein R2(gene name synonym)|uniprotkb:C33 antigen(gene name synonym)|uniprotkb:IA4(gene name synonym)|uniprotkb:Metastasis suppressor Kangai-1(gene name synonym)|uniprotkb:Suppressor of tumorigenicity 6 protein(gene name synonym)|uniprotkb:Tetraspanin-27(gene name synonym)|uniprotkb:CD82(gene name)|psi-mi:CD82(display_short)|uniprotkb:KAI1(gene name synonym)|uniprotkb:SAR2(gene name synonym)|uniprotkb:TSPAN27(gene name synonym)|uniprotkb:ST6(gene name synonym) psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083632|imex:IM-26075-73 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001020015.1|refseq:NP_002222.1|refseq:XP_006718286.1|ensembl:ENSG00000085117(gene)|ensembl:ENST00000227155(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000301(CD9/CD37/CD63 antigen)|interpro:IPR008952(Tetraspanin)|interpro:IPR018499|interpro:IPR018503|mint:P27701 intact:EBI-710918(chain-parent) - - chain-seq-start:1712|chain-seq-end:1972 figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:8Ow5hrE81Uf1Lqyb9lRIUg2Ng5I9606 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 intact-crc:9C392C901B26F024|rigid:Xld25MJIDOREDmRGDqQ9qWyAIuM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9WMX2-PRO_0000037550 uniprotkb:P02647 intact:EBI-8853273 intact:EBI-701692|uniprotkb:Q6LDN9|uniprotkb:Q6Q785|uniprotkb:A8K866|uniprotkb:Q9UCS8|uniprotkb:Q9UCT8|ensembl:ENSP00000236850|ensembl:ENSP00000352471|ensembl:ENSP00000364469|ensembl:ENSP00000364472 psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:apoa1_human(display_long)|uniprotkb:APOA1(gene name)|psi-mi:APOA1(display_short)|uniprotkb:Apolipoprotein A1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083624|imex:IM-26075-31 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-710918(chain-parent) refseq:NP_000030.1|refseq:NP_001304946.1|refseq:NP_001304947.1|refseq:NP_001304950.1|dip:DIP-29619N|ensembl:ENSG00000118137(gene)|ensembl:ENST00000236850(transcript)|ensembl:ENST00000359492(transcript)|ensembl:ENST00000375320(transcript)|ensembl:ENST00000375323(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002719"(negative regulation of cytokine production involved in immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007584"(response to nutrient)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0009986"(cell surface)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010898"(positive regulation of triglyceride catabolic process)|go:"GO:0010903"(negative regulation of very-low-density lipoprotein particle remodeling)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0015485"(cholesterol binding)|go:"GO:0018158"(protein oxidation)|go:"GO:0018206"(peptidyl-methionine modification)|go:"GO:0019899"(enzyme binding)|go:"GO:0019915"(lipid storage)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030300"(regulation of intestinal cholesterol absorption)|go:"GO:0030301"(cholesterol transport)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032489"(regulation of Cdc42 protein signal transduction)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|go:"GO:0034190"(apolipoprotein receptor binding)|go:"GO:0034191"(apolipoprotein A-I receptor binding)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034363"(intermediate-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034365"(discoidal high-density lipoprotein particle)|go:"GO:0034366"(spherical high-density lipoprotein particle)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034384"(high-density lipoprotein particle clearance)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042158"(lipoprotein biosynthetic process)|go:"GO:0042493"|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0043627"(response to estrogen)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0045499"(chemorepellent activity)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050821"(protein stabilization)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0051180"(vitamin transport)|go:"GO:0051345"(positive regulation of hydrolase activity)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0055091"(phospholipid homeostasis)|go:"GO:0055102"(lipase inhibitor activity)|go:"GO:0060192"(negative regulation of lipase activity)|go:"GO:0060228"(phosphatidylcholine-sterol O-acyltransferase activator activity)|go:"GO:0060354"(negative regulation of cell adhesion molecule production)|go:"GO:0060761"(negative regulation of response to cytokine stimulus)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070508"(cholesterol import)|go:"GO:0070653"(high-density lipoprotein particle receptor binding)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0072562"(blood microparticle)|go:"GO:0120020"(cholesterol transfer activity)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902995"(positive regulation of phospholipid efflux)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000074(Apolipoprotein A1/A4/E)|mint:P02647|rcsb pdb:1AV1|rcsb pdb:1GW3|rcsb pdb:1GW4|rcsb pdb:1ODP|rcsb pdb:1ODQ|rcsb pdb:1ODR|rcsb pdb:2MSC|rcsb pdb:2MSD|rcsb pdb:2MSE|rcsb pdb:2N5E|rcsb pdb:3K2S|rcsb pdb:3R2P|rcsb pdb:4V6M|rcsb pdb:6CC9|rcsb pdb:6CCH|rcsb pdb:6CCX|rcsb pdb:6CLZ|rcsb pdb:6CM1|rcsb pdb:6PTS|rcsb pdb:6PTW|rcsb pdb:6W4E|rcsb pdb:6W4F|rcsb pdb:7KJR|reactome:R-HSA-114608|reactome:R-HSA-1369062|reactome:R-HSA-1989781|reactome:R-HSA-2168880|reactome:R-HSA-3000471|reactome:R-HSA-3000480|reactome:R-HSA-381426|reactome:R-HSA-5682113|reactome:R-HSA-8957275|reactome:R-HSA-8963888|reactome:R-HSA-8963896|reactome:R-HSA-8963901|reactome:R-HSA-8964011|reactome:R-HSA-8964058|reactome:R-HSA-9707616|reactome:R-HSA-975634|reactome:R-HSA-977225 - chain-seq-start:1712|chain-seq-end:1972 - figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 rogid:yEzPDeU8Uu/43dkLLOBAy6ey1vs9606 intact-crc:9C05502B81A2CD7F|rigid:zfYYrYJ6PRc8o5LsPwPCo/rhtZU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9WMX2-PRO_0000037550 uniprotkb:Q06481 intact:EBI-8853273 intact:EBI-79306|uniprotkb:Q13861|uniprotkb:Q14594|uniprotkb:Q14662|uniprotkb:Q71U10|uniprotkb:Q7M4L3|uniprotkb:Q9BT36|ensembl:ENSP00000263574|ensembl:ENSP00000497691|uniprotkb:B3KXX9|uniprotkb:H7BXI4 psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:aplp2_human(display_long)|uniprotkb:APPH(gene name synonym)|uniprotkb:APPL2(gene name synonym)|uniprotkb:APLP2(gene name)|psi-mi:APLP2(display_short)|uniprotkb:Amyloid protein homolog(gene name synonym)|uniprotkb:CDEI box-binding protein(gene name synonym)|uniprotkb:"Amyloid beta (A4) precursor-like protein 2"(gene name synonym)|uniprotkb:Amyloid-like protein 2(gene name synonym)|uniprotkb:Sperm membrane protein YWK-II(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083620|imex:IM-26075-89 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-710918(chain-parent) refseq:NP_001135748.1|refseq:NP_001135749.1|refseq:NP_001135750.1|refseq:NP_001633.1|ensembl:ENSG00000084234(gene)|ensembl:ENST00000263574(transcript)|ensembl:ENST00000650012(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008201"(heparin binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031092"(platelet alpha granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002223(Proteinase inhibitor I2, Kunitz metazoa)|interpro:IPR008154(Amyloidogenic glycoprotein, extracellular)|interpro:IPR008155(Amyloidogenic glycoprotein, core)|interpro:IPR011178(Amyloidogenic glycoprotein, copper-binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015849(Amyloidogenic glycoprotein, heparin-binding)|interpro:IPR019543|interpro:IPR019744|interpro:IPR019745|interpro:IPR020901|interpro:IPR024329|interpro:IPR036176|interpro:IPR036454|interpro:IPR036669|interpro:IPR036880|mint:Q06481|rcsb pdb:5JBT|rcsb pdb:5TPT|reactome:R-HSA-114608|reactome:R-HSA-381426|reactome:R-HSA-8957275|refseq:NP_001230228.1|dip:DIP-31047N - chain-seq-start:1712|chain-seq-end:1972 - figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 rogid:WBmrQxD6+MjRPRNHt63XDIs9++o9606 intact-crc:5429953EA6CA4BF4|rigid:qF3z3QAixlveXXdjwzMsnqbGteg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9WMX2-PRO_0000037550 uniprotkb:P02679 intact:EBI-8853273 intact:EBI-1034422|uniprotkb:P04469|uniprotkb:P04470|uniprotkb:Q96A14|uniprotkb:Q96KJ3|uniprotkb:A8K057|uniprotkb:Q53Y18|uniprotkb:Q9UC62|uniprotkb:Q9UC63|uniprotkb:Q9UCF3|ensembl:ENSP00000336829 psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:fibg_human(display_long)|uniprotkb:FGG(gene name)|psi-mi:FGG(display_short)|uniprotkb:PRO2061(orf name) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083590|imex:IM-26075-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-710918(chain-parent) refseq:NP_000500.2|refseq:NP_068656.2|ensembl:ENSG00000171557(gene)|ensembl:ENST00000336098(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0009306"(protein secretion)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031639"(plasminogen activation)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0034622"|go:"GO:0036345"(platelet maturation)|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0046872"(metal ion binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051258"(protein polymerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0090277"(positive regulation of peptide hormone secretion)|go:"GO:0090331"(negative regulation of platelet aggregation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR012290(Fibrinogen, alpha/beta/gamma chain, coiled coil)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|interpro:IPR037581|mint:P02679|rcsb pdb:1DUG|rcsb pdb:1FIB|rcsb pdb:1FIC|rcsb pdb:1FID|rcsb pdb:1FZA|go:"GO:0070527"(platelet aggregation)|rcsb pdb:1FZB|rcsb pdb:1FZC|rcsb pdb:1FZE|rcsb pdb:1FZF|rcsb pdb:1FZG|rcsb pdb:1LT9|rcsb pdb:1LTJ|rcsb pdb:1N86|rcsb pdb:1N8E|rcsb pdb:1RE3|rcsb pdb:1RE4|rcsb pdb:1RF0|rcsb pdb:1RF1|rcsb pdb:2A45|rcsb pdb:2FFD|rcsb pdb:2FIB|rcsb pdb:2H43|rcsb pdb:2HLO|rcsb pdb:2HOD|rcsb pdb:2HPC|rcsb pdb:2HWL|rcsb pdb:2OYH|rcsb pdb:2OYI|rcsb pdb:2VDO|rcsb pdb:2VDP|rcsb pdb:2VDQ|rcsb pdb:2VDR|rcsb pdb:2VR3|rcsb pdb:2XNX|rcsb pdb:2XNY|rcsb pdb:2Y7L|rcsb pdb:2Z4E|rcsb pdb:3BVH|rcsb pdb:3E1I|rcsb pdb:2Q9I|rcsb pdb:3FIB|rcsb pdb:3GHG|rcsb pdb:3H32|rcsb pdb:3HUS|rcsb pdb:4B60|reactome:R-HSA-114608|reactome:R-HSA-1236974|reactome:R-HSA-140875|reactome:R-HSA-166058|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5674135|reactome:R-HSA-5686938|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8957275|reactome:R-HSA-9649948|reactome:R-HSA-9656223|dip:DIP-29644N - chain-seq-start:1712|chain-seq-end:1972 - figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 rogid:QKWesyU4/fduceFtu5zq31oGhYI9606 intact-crc:4A2796AC5506061E|rigid:UdBV3ywmcm/b+Jz8lTrwm6Q66gk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NY26 uniprotkb:Q9WMX2-PRO_0000037550 intact:EBI-726491|uniprotkb:Q8N2H7|uniprotkb:Q9BTV0|uniprotkb:Q9UBI7|uniprotkb:Q9Y2Z7|uniprotkb:Q9Y380|uniprotkb:B4DDY7|uniprotkb:Q5T4K1|ensembl:ENSP00000309710|ensembl:ENSP00000348535|ensembl:ENSP00000357610|ensembl:ENSP00000357612|ensembl:ENSP00000479421|ensembl:ENSP00000484182 intact:EBI-8853273 psi-mi:s39a1_human(display_long)|uniprotkb:Zrt- and Irt-like protein 1(gene name synonym)|uniprotkb:Solute carrier family 39 member 1(gene name synonym)|uniprotkb:Zinc-iron-regulated transporter-like(gene name synonym)|uniprotkb:SLC39A1(gene name)|psi-mi:SLC39A1(display_short)|uniprotkb:IRT1(gene name synonym)|uniprotkb:ZIP1(gene name synonym)|uniprotkb:ZIRTL(gene name synonym)|uniprotkb:CGI-08(orf name)|uniprotkb:CGI-71(orf name) psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083599|imex:IM-26075-87 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055252.2|refseq:NP_001258890.1|refseq:NP_001258886.1|refseq:NP_001258887.1|refseq:NP_001258888.1|refseq:NP_001258889.1|ensembl:ENSG00000143570(gene)|ensembl:ENST00000310483(transcript)|ensembl:ENST00000356205(transcript)|ensembl:ENST00000368621(transcript)|ensembl:ENST00000368623(transcript)|ensembl:ENST00000617697(transcript)|ensembl:ENST00000621013(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006812"(cation transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022890"(inorganic cation transmembrane transporter activity)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0060173"(limb development)|go:"GO:0071577"(zinc ion transmembrane transport)|interpro:IPR003689(Zinc/iron permease)|mint:Q9NY26|reactome:R-HSA-442380 intact:EBI-710918(chain-parent) - - chain-seq-start:1712|chain-seq-end:1972 figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:zCseDWZJvewH3FMzVqYin/QyNFc9606 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 intact-crc:F2F3D1EE02A736F1|rigid:xc+WkJH7FLHYobjhbzUelqnAy14 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P23378 uniprotkb:Q9WMX2-PRO_0000037550 intact:EBI-2509907|ensembl:ENSP00000370737|uniprotkb:Q2M2F8 intact:EBI-8853273 psi-mi:gcsp_human(display_long)|uniprotkb:GLDC(gene name)|psi-mi:GLDC(display_short)|uniprotkb:GCSP(gene name synonym)|uniprotkb:Glycine decarboxylase(gene name synonym)|uniprotkb:Glycine cleavage system P protein(gene name synonym)|uniprotkb:"Glycine dehydrogenase (aminomethyl-transferring)"(gene name synonym) psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083603|imex:IM-26075-29 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000178445(gene)|ensembl:ENST00000321612(transcript)|go:"GO:0004375"("glycine dehydrogenase (decarboxylating) activity")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0005960"(glycine cleavage complex)|go:"GO:0006546"(glycine catabolic process)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016594"(glycine binding)|go:"GO:0016829"(lyase activity)|go:"GO:0019464"(glycine decarboxylation via glycine cleavage system)|go:"GO:0019899"(enzyme binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0036255"(response to methylamine)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070280"(pyridoxal binding)|go:"GO:1903442"(response to lipoic acid)|interpro:IPR001597(Aromatic amino acid beta-eliminating lyase/threonine aldolase)|interpro:IPR003437(Glycine cleavage system P-protein)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR020581|rcsb pdb:6I33|rcsb pdb:6I34|rcsb pdb:6I35|reactome:R-HSA-6783984|refseq:NP_000161.2 intact:EBI-710918(chain-parent) - - chain-seq-start:1712|chain-seq-end:1972 figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:zNBF42twnLftxt9dEQsTcGD5dts9606 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 intact-crc:047B7DCAD9ECB97F|rigid:UmLduG3ZaVNfJuDAWC/UzKJOPdg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9WMX2-PRO_0000037550 uniprotkb:Q56VL3 intact:EBI-8853273 intact:EBI-6152758|uniprotkb:Q8N544|uniprotkb:B4DPE7|ensembl:ENSP00000423014 psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:ocad2_human(display_long)|uniprotkb:Ovarian carcinoma immunoreactive antigen-like protein(gene name synonym)|uniprotkb:OCIAD2(gene name)|psi-mi:OCIAD2(display_short) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083467|imex:IM-26075-65 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-710918(chain-parent) refseq:NP_001014446.1|refseq:NP_689611.1|refseq:NP_001273702.1|ensembl:ENSG00000145247(gene)|ensembl:ENST00000508632(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006897"(endocytosis)|go:"GO:0009617"(response to bacterium)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|interpro:IPR009764(Ovarian carcinoma immunoreactive antigen)|interpro:IPR040187 - chain-seq-start:1712|chain-seq-end:1972 - figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 rogid:z4I/nxTOVnbJ/RZhY11VYbBas0g9606 intact-crc:7D86BCB67545B811|rigid:q5Ru9P0AdFP104PbftsLC9+FbOY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9WMX2-PRO_0000037550 uniprotkb:Q6UX53 intact:EBI-8853273 intact:EBI-9083532|uniprotkb:A8K247|uniprotkb:Q8WUI1|ensembl:ENSP00000377796 psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:met7b_human(display_long)|uniprotkb:Methyltransferase-like protein 7B(gene name synonym)|uniprotkb:UNQ594/PRO1180(orf name)|uniprotkb:METTL7B(gene name)|psi-mi:METTL7B(display_short) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083544|imex:IM-26075-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-710918(chain-parent) refseq:NP_689850.2|ensembl:ENSG00000170439(gene)|ensembl:ENST00000394252(transcript)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0018708"(thiol S-methyltransferase activity)|go:"GO:0032259"(methylation)|interpro:IPR013216(Methyltransferase type 11)|interpro:IPR029063 - chain-seq-start:1712|chain-seq-end:1972 - figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 rogid:x+APoJRErfhmcxxr3xckx0kKm3c9606 intact-crc:9B2E832F15AB7E52|rigid:OZ6CNusK5c7bFTbYxAuPdEhUAg4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9WMX2-PRO_0000037550 uniprotkb:Q15125 intact:EBI-8853273 intact:EBI-3915253|uniprotkb:Q6IBI9|uniprotkb:Q6FGL3|ensembl:ENSP00000417052 psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:ebp_human(display_long)|uniprotkb:EBP(gene name)|psi-mi:EBP(display_short)|uniprotkb:Cholestenol Delta-isomerase(gene name synonym)|uniprotkb:"Delta(8)-Delta(7) sterol isomerase"(gene name synonym)|uniprotkb:Emopamil-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083439|imex:IM-26075-83 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-710918(chain-parent) refseq:NP_006570.1|ensembl:ENSG00000147155(gene)|ensembl:ENST00000495186(transcript)|go:"GO:0000247"(C-8 sterol isomerase activity)|go:"GO:0001501"(skeletal system development)|go:"GO:0004769"(steroid delta-isomerase activity)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033489"(cholesterol biosynthetic process via desmosterol)|go:"GO:0033490"(cholesterol biosynthetic process via lathosterol)|go:"GO:0042802"(identical protein binding)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0047750"(cholestenol delta-isomerase activity)|interpro:IPR007905(Emopamil-binding)|interpro:IPR033118|rcsb pdb:6OHT|rcsb pdb:6OHU|reactome:R-HSA-6807047|reactome:R-HSA-6807062 - chain-seq-start:1712|chain-seq-end:1972 - figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 rogid:7XfeeD/twqYll0Hv4YuJUbmAVJ09606 intact-crc:F40CD18342C789E2|rigid:aLPIt1nQBy07cAkm970xf3qMQTg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9WMX2-PRO_0000037550 uniprotkb:P23284 intact:EBI-8853273 intact:EBI-359252|uniprotkb:Q9BVK5|uniprotkb:A8K534|uniprotkb:Q6IBH5|ensembl:ENSP00000300026 psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:ppib_human(display_long)|uniprotkb:PPIB(gene name)|psi-mi:PPIB(display_short)|uniprotkb:CYPB(gene name synonym)|uniprotkb:Cyclophilin B(gene name synonym)|uniprotkb:S-cyclophilin(gene name synonym)|uniprotkb:CYP-S1(gene name synonym)|uniprotkb:Rotamase B(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083688|imex:IM-26075-79 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-710918(chain-parent) refseq:NP_000933.1|ensembl:ENSG00000166794(gene)|ensembl:ENST00000300026(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003723"(RNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016020"(membrane)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042470"(melanosome)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0060348"(bone development)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR029000|mint:P23284|rcsb pdb:1CYN|rcsb pdb:3ICH|rcsb pdb:3ICI|reactome:R-HSA-1650814 - chain-seq-start:1712|chain-seq-end:1972 - figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 rogid:h6nKaPUyEYUctYuu/3XfFhM4y9c9606 intact-crc:76104A23C4181F35|rigid:o05ShtTiYuPa8MQwUhO7GNVywT0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P01009 uniprotkb:Q9WMX2-PRO_0000037541 intact:EBI-986224|uniprotkb:Q7M4R2|uniprotkb:Q86U18|uniprotkb:Q86U19|uniprotkb:Q96BF9|uniprotkb:Q96ES1|uniprotkb:Q9P1P0|uniprotkb:A6PX14|uniprotkb:Q0PVP5|uniprotkb:Q13672|uniprotkb:Q53XB8|uniprotkb:Q5U0M1|uniprotkb:B2RDQ8|uniprotkb:Q9UCE6|uniprotkb:Q9UCM3|ensembl:ENSP00000348068|ensembl:ENSP00000376802|ensembl:ENSP00000376803|ensembl:ENSP00000385960|ensembl:ENSP00000390299|ensembl:ENSP00000408474|ensembl:ENSP00000416066|ensembl:ENSP00000416354|ensembl:ENSP00000490054 intact:EBI-6863754 psi-mi:a1at_human(display_long)|uniprotkb:Alpha-1 protease inhibitor(gene name synonym)|uniprotkb:Alpha-1-antiproteinase(gene name synonym)|uniprotkb:AAT(gene name synonym)|uniprotkb:PI(gene name synonym)|uniprotkb:PRO0684(orf name)|uniprotkb:PRO2209(orf name)|uniprotkb:SERPINA1(gene name)|psi-mi:SERPINA1(display_short)|uniprotkb:Serpin A1(gene name synonym) psi-mi:q9wmx2-pro_0000037541(display_long) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083366|imex:IM-26075-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000286.3|refseq:NP_001002235.1|refseq:NP_001002236.1|refseq:NP_001121172.1|refseq:NP_001121173.1|refseq:NP_001121174.1|refseq:NP_001121175.1|refseq:NP_001121176.1|refseq:NP_001121177.1|refseq:NP_001121178.1|refseq:NP_001121179.1|refseq:XP_016876859.1|dip:DIP-35493N|ensembl:ENSG00000197249(gene)|ensembl:ENST00000355814(transcript)|ensembl:ENST00000393087(transcript)|ensembl:ENST00000393088(transcript)|ensembl:ENST00000404814(transcript)|ensembl:ENST00000437397(transcript)|ensembl:ENST00000440909(transcript)|ensembl:ENST00000448921(transcript)|ensembl:ENST00000449399(transcript)|ensembl:ENST00000636712(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006953"(acute-phase response)|go:"GO:0007596"(blood coagulation)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P01009|rcsb pdb:1ATU|rcsb pdb:1EZX|rcsb pdb:1HP7|rcsb pdb:1D5S|rcsb pdb:1IZ2|rcsb pdb:1KCT|rcsb pdb:1OO8|rcsb pdb:1OPH|rcsb pdb:1PSI|rcsb pdb:1QLP|rcsb pdb:1QMB|rcsb pdb:2D26|rcsb pdb:2QUG|rcsb pdb:3CWL|rcsb pdb:3CWM|rcsb pdb:3DRM|rcsb pdb:3DRU|rcsb pdb:3NDD|rcsb pdb:3NDF|rcsb pdb:3NE4|rcsb pdb:3T1P|rcsb pdb:4PYW|rcsb pdb:5IO1|rcsb pdb:5NBU|rcsb pdb:5NBV|rcsb pdb:6HX4|rcsb pdb:6I4V|rcsb pdb:6I7U|rcsb pdb:6IAY|rcsb pdb:6ROD|rcsb pdb:7AEL|rcsb pdb:7API|rcsb pdb:7NPK|rcsb pdb:7NPL|rcsb pdb:8API|rcsb pdb:9API|reactome:R-HSA-114608|reactome:R-HSA-204005|reactome:R-HSA-381426|reactome:R-HSA-5694530|reactome:R-HSA-6798695|reactome:R-HSA-8957275 intact:EBI-710918(chain-parent) - - chain-seq-start:2|chain-seq-end:191 figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:eIbjQWRWsWv+B28IcSUIKJ+Eros9606 rogid:zS2NVHBt5ng21TAtWlc6Q0daM5g333284 intact-crc:B1D082926A741940|rigid:0xaFWgyvYG3y4G3/eN253ukjKnE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P02750 uniprotkb:Q9WMX2-PRO_0000037550 intact:EBI-9083443|uniprotkb:Q8N4F5|uniprotkb:Q96QZ4|ensembl:ENSP00000302621 intact:EBI-8853273 psi-mi:a2gl_human(display_long)|uniprotkb:LRG1(gene name)|psi-mi:LRG1(display_short)|uniprotkb:LRG(gene name synonym) psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083459|imex:IM-26075-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_443204.1|dip:DIP-60317N|ensembl:ENSG00000171236(gene)|ensembl:ENST00000306390(transcript)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0009617"(response to bacterium)|go:"GO:0016020"(membrane)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|reactome:R-HSA-6798695|go:"GO:0035580"(specific granule lumen) intact:EBI-710918(chain-parent) - - chain-seq-start:1712|chain-seq-end:1972 figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:di653qGxwl+poYXeOOsZfNxESIw9606 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 intact-crc:9D3E5F4D2158CC73|rigid:kJ8Q0Ovt5ZLB0mzeebVY7EVnrnA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06733 uniprotkb:Q9WMX2-PRO_0000037541 intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6 intact:EBI-6863754 psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym) psi-mi:q9wmx2-pro_0000037541(display_long) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083322|imex:IM-26075-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667 intact:EBI-710918(chain-parent) - - chain-seq-start:2|chain-seq-end:191 figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:RmP7cr55H8ylcgBOEyivwljIE+09606 rogid:zS2NVHBt5ng21TAtWlc6Q0daM5g333284 intact-crc:EF8F8663ED4D57C3|rigid:FjrO4a8iSkxvgsE2lR/rGe8MHDc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9WMX2-PRO_0000037541 uniprotkb:O14818 intact:EBI-6863754 intact:EBI-603272|uniprotkb:Q9BR53|uniprotkb:Q9H4K5|uniprotkb:Q9UEU8|uniprotkb:B2R515|uniprotkb:Q5JXJ2|ensembl:ENSP00000359910 psi-mi:q9wmx2-pro_0000037541(display_long) psi-mi:psa7_human(display_long)|uniprotkb:PSMA7(gene name)|psi-mi:PSMA7(display_short)|uniprotkb:Proteasome subunit RC6-1(gene name synonym)|uniprotkb:Proteasome subunit XAPC7(gene name synonym)|uniprotkb:HSPC(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083370|imex:IM-26075-81 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-710918(chain-parent) refseq:NP_002783.1|dip:DIP-29363N|ensembl:ENSG00000101182(gene)|ensembl:ENST00000370873(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098794"(postsynapse)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035190|mint:O14818|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 - chain-seq-start:2|chain-seq-end:191 - figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:zS2NVHBt5ng21TAtWlc6Q0daM5g333284 rogid:J1M+b+VK02BAn2OnZISjjlmO8dc9606 intact-crc:1A8A66E4202E5EFA|rigid:VPq0HfdLNbUQYNX99u7ceEPiFug false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P26641 uniprotkb:Q9WMX2-PRO_0000037541 intact:EBI-351467|uniprotkb:Q6PJ62|uniprotkb:Q6PK31|uniprotkb:Q96CU2|uniprotkb:Q9P196|intact:EBI-2321928|uniprotkb:B4DTG2|ensembl:ENSP00000331901 intact:EBI-6863754 psi-mi:ef1g_human(display_long)|uniprotkb:PRO1608(orf name)|uniprotkb:EEF1G(gene name)|psi-mi:EEF1G(display_short)|uniprotkb:EF1G(gene name synonym)|uniprotkb:eEF-1B gamma(gene name synonym) psi-mi:q9wmx2-pro_0000037541(display_long) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9077454|imex:IM-26075-61 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001395.1|ensembl:ENSG00000254772(gene)|ensembl:ENST00000329251(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006414"(translational elongation)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001662(Translation elongation factor EF1B, gamma chain, conserved)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR036433|interpro:IPR040079|mint:P26641|rcsb pdb:1PBU|rcsb pdb:5DQS|rcsb pdb:5JPO|reactome:R-HSA-156842|dip:DIP-32516N intact:EBI-710918(chain-parent) - - chain-seq-start:2|chain-seq-end:191 figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:biVN96umeEdPm/wvPN4VwbSRHTs9606 rogid:zS2NVHBt5ng21TAtWlc6Q0daM5g333284 intact-crc:08BAC16E2C3B20B1|rigid:ZvzzrwXWpP0KzsGXpzZFvd/sb7k false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9WMX2-PRO_0000037550 uniprotkb:Q6N075 intact:EBI-8853273 intact:EBI-3920969|ensembl:ENSP00000332624|uniprotkb:Q96IA5|uniprotkb:Q8N7W8|uniprotkb:Q6NW04|uniprotkb:Q8NCK0|uniprotkb:G3V1N7 psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:mfsd5_human(display_long)|uniprotkb:MFSD5(gene name)|psi-mi:MFSD5(display_short)|uniprotkb:Major facilitator superfamily domain-containing protein 5(gene name synonym)|uniprotkb:Molybdate transporter 2 homolog(gene name synonym)|uniprotkb:UNQ832/PRO1759(orf name) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083729|imex:IM-26075-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-710918(chain-parent) ensembl:ENSG00000182544(gene)|ensembl:ENST00000329548(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0015098"(molybdate ion transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008509(Protein of unknown function DUF791)|interpro:IPR030163|interpro:IPR036259|refseq:NP_001164261.1|refseq:NP_116278.3|refseq:XP_005269254.1|refseq:XP_005269255.1 - chain-seq-start:1712|chain-seq-end:1972 - figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 rogid:uUvOxvg/XeIC9mL4pCCk87P1ElI9606 intact-crc:A5CB9D3F220E478B|rigid:7wN9pgt43K0a9dhAZDYOvFe6tc0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9WMX2-PRO_0000037550 uniprotkb:P04920 intact:EBI-8853273 intact:EBI-1390787|uniprotkb:Q45EY5|uniprotkb:Q969L3|uniprotkb:D3DX05|uniprotkb:B2R6T0|uniprotkb:B4DIT0|uniprotkb:F8W682|ensembl:ENSP00000405600|ensembl:ENSP00000419412 psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:b3a2_human(display_long)|uniprotkb:SLC4A2(gene name)|psi-mi:SLC4A2(display_short)|uniprotkb:AE2(gene name synonym)|uniprotkb:EPB3L1(gene name synonym)|uniprotkb:HKB3(gene name synonym)|uniprotkb:MPB3L(gene name synonym)|uniprotkb:Non-erythroid band 3-like protein(gene name synonym)|uniprotkb:Solute carrier family 4 member 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083721|imex:IM-26075-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-710918(chain-parent) refseq:NP_001186621.1|refseq:NP_001186623.1|refseq:NP_003031.3|refseq:NP_001186622.1|interpro:IPR003020(Bicarbonate transporter, eukaryotic)|interpro:IPR011531(Bicarbonate transporter, C-terminal)|interpro:IPR013769(Bicarbonate transporter, cytoplasmic)|interpro:IPR016152(Phosphotransferase/anion transporter)|interpro:IPR018241|reactome:R-HSA-425381|ensembl:ENSG00000164889(gene)|ensembl:ENST00000413384(transcript)|ensembl:ENST00000485713(transcript)|go:"GO:0005452"(inorganic anion exchanger activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006820"(anion transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008509"(anion transmembrane transporter activity)|go:"GO:0015301"("anion:anion antiporter activity")|go:"GO:0015701"(bicarbonate transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0048565"(digestive tract development)|go:"GO:0050801"(ion homeostasis)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0055085"(transmembrane transport)|interpro:IPR001717(Anion exchange protein)|interpro:IPR002978(Anion exchange protein 2) - chain-seq-start:1712|chain-seq-end:1972 - figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 rogid:khJ5Stwond2oto/uqDNzRYDX48U9606 intact-crc:984DB486670C0098|rigid:0XDySmePoCvquO9bt6F7y5wy+PE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9WMX2-PRO_0000037550 uniprotkb:Q99942 intact:EBI-8853273 intact:EBI-348482|ensembl:ENSP00000364235|ensembl:ENSP00000387879|ensembl:ENSP00000388795|ensembl:ENSP00000401172|ensembl:ENSP00000413131|ensembl:ENSP00000415127|ensembl:ENSP00000415784|uniprotkb:A2BFI6|uniprotkb:Q0VDB7|uniprotkb:Q9UMQ2|uniprotkb:B2R4K3 psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:rnf5_human(display_long)|uniprotkb:RNF5(gene name)|psi-mi:RNF5(display_short)|uniprotkb:G16(gene name synonym)|uniprotkb:RING finger protein 5(gene name synonym)|uniprotkb:Protein G16(gene name synonym)|uniprotkb:NG2(gene name synonym)|uniprotkb:RMA1(gene name synonym)|uniprotkb:Ram1 homolog(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF5(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083717|imex:IM-26075-53 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-710918(chain-parent) refseq:NP_008844.1|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009617"(response to bacterium)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031648"(protein destabilization)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0036503"(ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|ensembl:ENST00000456167(transcript)|ensembl:ENSG00000183574(gene)|ensembl:ENSG00000204308(gene)|ensembl:ENSG00000223767(gene)|ensembl:ENSG00000225452(gene)|ensembl:ENSG00000227277(gene)|ensembl:ENSG00000228405(gene)|ensembl:ENSG00000228907(gene)|ensembl:ENST00000375094(transcript)|ensembl:ENST00000413786(transcript)|ensembl:ENST00000432616(transcript)|ensembl:ENST00000445885(transcript)|ensembl:ENST00000449794(transcript)|ensembl:ENST00000453473(transcript)|go:"GO:0055085"(transmembrane transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-382556|reactome:R-HSA-5678895|reactome:R-HSA-901032|go:"GO:0044877"(protein-containing complex binding)|dip:DIP-29268N - chain-seq-start:1712|chain-seq-end:1972 - figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 rogid:eHlCD+xbWmpzFdhVn6OC5MPqeNE9606 intact-crc:900E0A7430A9A338|rigid:oqaueprK0SVU2Xygo9ekDTQVYEc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q00765 uniprotkb:Q9WMX2-PRO_0000037550 intact:EBI-1549827|uniprotkb:Q04198|uniprotkb:Q5QGT0|uniprotkb:Q9BWH9|uniprotkb:D3DT04|uniprotkb:B7Z681|ensembl:ENSP00000368959 intact:EBI-8853273 psi-mi:reep5_human(display_long)|uniprotkb:REEP5(gene name)|psi-mi:REEP5(display_short)|uniprotkb:C5orf18(gene name synonym)|uniprotkb:DP1(gene name synonym)|uniprotkb:TB2(gene name synonym)|uniprotkb:Polyposis locus protein 1(gene name synonym)|uniprotkb:Protein TB2(gene name synonym) psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083725|imex:IM-26075-55 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005660.4|ensembl:ENSG00000129625(gene)|ensembl:ENST00000379638(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0071782"(endoplasmic reticulum tubular network)|interpro:IPR004345(TB2/DP1 and HVA22 related protein)|reactome:R-HSA-381753 intact:EBI-710918(chain-parent) - - chain-seq-start:1712|chain-seq-end:1972 figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:Z6Lzi37F0AfHZBnHri7k4EUpSRQ9606 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 intact-crc:335AEEE588D7E4EF|rigid:dCmD2kM0/eR8SQRoKp+sRImzWKo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P25311 uniprotkb:Q9WMX2-PRO_0000037550 intact:EBI-2513837|ensembl:ENSP00000292401|uniprotkb:Q5XKQ4|uniprotkb:O60386|uniprotkb:Q8N4N0|uniprotkb:D6W5T8 intact:EBI-8853273 psi-mi:za2g_human(display_long)|uniprotkb:AZGP1(gene name)|psi-mi:AZGP1(display_short)|uniprotkb:ZAG(gene name synonym)|uniprotkb:ZNGP1(gene name synonym) psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083694|imex:IM-26075-37 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000160862(gene)|ensembl:ENST00000292401(transcript)|go:"GO:0001580"(detection of chemical stimulus involved in sensory perception of bitter taste)|go:"GO:0001895"(retina homeostasis)|go:"GO:0002476"(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0007155"(cell adhesion)|go:"GO:0008285"(negative regulation of cell population proliferation)|interpro:IPR036179|interpro:IPR037055|mint:P25311|rcsb pdb:1T7V|rcsb pdb:1T7W|rcsb pdb:1T7X|rcsb pdb:1T7Y|rcsb pdb:1T7Z|rcsb pdb:1T80|rcsb pdb:1ZAG|rcsb pdb:3ES6|rcsb pdb:6R2U|reactome:R-HSA-5223345|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|refseq:NP_001176.1 intact:EBI-710918(chain-parent) - - chain-seq-start:1712|chain-seq-end:1972 figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:3Fp6qALNiZRqsI8Kh2lTQ9IMYek9606 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 intact-crc:D23B6B9C0C992F67|rigid:zwcLET6AQAoouUa0cfmhZ/OIyh0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P22310 uniprotkb:Q9WMX2-PRO_0000037550 intact:EBI-3937244|uniprotkb:B2R937|ensembl:ENSP00000362508|uniprotkb:Q5DT00|uniprotkb:B8K288 intact:EBI-8853273 psi-mi:ud14_human(display_long)|uniprotkb:UGT1A4(gene name)|psi-mi:UGT1A4(display_short)|uniprotkb:GNT1(gene name synonym)|uniprotkb:UGT1(gene name synonym)|uniprotkb:Bilirubin-specific UDPGT isozyme 2(gene name synonym)|uniprotkb:UDP-glucuronosyltransferase 1-D(gene name synonym)|uniprotkb:UDP-glucuronosyltransferase 1-4(gene name synonym) psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083680|imex:IM-26075-109 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000244474(gene)|ensembl:ENST00000373409(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006789"(bilirubin conjugation)|go:"GO:0015020"(glucuronosyltransferase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0042167"(heme catabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045922"(negative regulation of fatty acid metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0052695"(cellular glucuronidation)|go:"GO:0052696"(flavonoid glucuronidation)|go:"GO:0052697"(xenobiotic glucuronidation)|go:"GO:0070640"(vitamin D3 metabolic process)|go:"GO:1904224"(negative regulation of glucuronosyltransferase activity)|go:"GO:2001030"(negative regulation of cellular glucuronidation)|interpro:IPR002213(UDP-glucuronosyl/UDP-glucosyltransferase)|interpro:IPR035595|reactome:R-HSA-156588|reactome:R-HSA-189483|reactome:R-HSA-5579016|refseq:NP_009051.1 intact:EBI-710918(chain-parent) - - chain-seq-start:1712|chain-seq-end:1972 figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:LjpxvfzBCJowfUwyBqui/mXjeeA9606 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 intact-crc:CC0EF79F531ABB74|rigid:pI43nWEseKpXgy+GLsfUJYvwduU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q06055 uniprotkb:Q9WMX2-PRO_0000037550 intact:EBI-3912136|uniprotkb:B3KQQ6|ensembl:ENSP00000340315|ensembl:ENSP00000377878|ensembl:ENSP00000447317|ensembl:ENSP00000448801 intact:EBI-8853273 psi-mi:at5g2_human(display_long)|uniprotkb:ATP5MC2(gene name)|psi-mi:ATP5MC2(display_short)|uniprotkb:ATP synthase lipid-binding protein(gene name synonym)|uniprotkb:ATP synthase membrane subunit c locus 2(gene name synonym)|uniprotkb:ATP synthase proteolipid P2(gene name synonym)|uniprotkb:"ATP synthase proton-transporting mitochondrial F(0) complex subunit C2"(gene name synonym)|uniprotkb:ATP5G2(gene name synonym)|uniprotkb:ATPase protein 9(gene name synonym)|uniprotkb:ATPase subunit c(gene name synonym)|uniprotkb:PSEC0033(orf name) psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083661|imex:IM-26075-51 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001002031.1|refseq:NP_005167.2|ensembl:ENSG00000135390(gene)|ensembl:ENST00000338662(transcript)|ensembl:ENST00000394349(transcript)|ensembl:ENST00000552242(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0008289"(lipid binding)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045263"("proton-transporting ATP synthase complex, coupling factor F(o)")|interpro:IPR000454(ATPase, F0 complex, subunit C)|interpro:IPR002379(ATPase, F0/V0 complex, subunit C)|interpro:IPR020537|interpro:IPR035921|interpro:IPR038662|mint:Q06055|reactome:R-HSA-163210|reactome:R-HSA-8949613|ensembl:ENST00000549164(transcript)|refseq:NP_001317198.1|refseq:XP_016874949.1|refseq:XP_016874950.1 intact:EBI-710918(chain-parent) - - chain-seq-start:1712|chain-seq-end:1972 figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:4ZhP9IXjOV0f7aZYk2/ReIVZsDk9606 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 intact-crc:8D2A9136B508CCA9|rigid:/EbelLgrJ3nYjyHo/hoScEFB2DI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9WMX2-PRO_0000037550 uniprotkb:Q02818 intact:EBI-8853273 intact:EBI-2622179|uniprotkb:Q7Z4J7|uniprotkb:B2RD64|uniprotkb:Q9BUR1|uniprotkb:Q15838|intact:EBI-28978015|ensembl:ENSP00000385211|ensembl:ENSP00000385923 psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:nucb1_human(display_long)|uniprotkb:NUC(gene name synonym)|uniprotkb:CALNUC(gene name synonym)|uniprotkb:NUCB1(gene name)|psi-mi:NUCB1(display_short) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083648|imex:IM-26075-105 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-710918(chain-parent) ensembl:ENSP00000385923|ensembl:ENSP00000385211|refseq:NP_006175.2|refseq:XP_016882334.1|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072718"(response to cisplatin)|go:"GO:0090498"(extrinsic component of Golgi membrane)|go:"GO:0098547"(lumenal side of Golgi membrane)|go:"GO:1903533"(regulation of protein targeting)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR040250|interpro:IPR040253|mint:Q02818|rcsb pdb:1SNL|reactome:R-HSA-381426|reactome:R-HSA-8957275|ensembl:ENSG00000104805(gene)|ensembl:ENST00000405315(transcript)|ensembl:ENST00000407032(transcript)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome) - chain-seq-start:1712|chain-seq-end:1972 - figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 rogid:exoVYPq5+NxEpgkm/gAQay/Uwuk9606 intact-crc:FB7B5065E6CBEFE7|rigid:UcK4gdLThlBXw2IJKFND8IxZPaU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P04114 uniprotkb:Q9WMX2-PRO_0000037550 intact:EBI-3926040|uniprotkb:Q9UMN0|uniprotkb:P78479|uniprotkb:P78480|uniprotkb:Q7Z600|uniprotkb:Q13786|uniprotkb:O00502|uniprotkb:P78481|uniprotkb:Q4ZG63|uniprotkb:Q13779|uniprotkb:Q13788|uniprotkb:Q13785|uniprotkb:Q13787|uniprotkb:Q53QC8|ensembl:ENSP00000233242 intact:EBI-8853273 psi-mi:apob_human(display_long)|uniprotkb:APOB(gene name)|psi-mi:APOB(display_short) psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083628|imex:IM-26075-71 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000375.2|ensembl:ENSG00000084674(gene)|ensembl:ENST00000233242(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0008201"(heparin binding)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009566"(fertilization)|go:"GO:0009615"(response to virus)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010008"(endosome membrane)|go:"GO:0010269"(response to selenium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010744"(positive regulation of macrophage derived foam cell differentiation)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010886"(positive regulation of cholesterol storage)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0030301"(cholesterol transport)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031904"(endosome lumen)|go:"GO:0031983"(vesicle lumen)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0034359"(mature chylomicron)|go:"GO:0034360"(chylomicron remnant)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034363"(intermediate-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034374"(low-density lipoprotein particle remodeling)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0035473"(lipase binding)|go:"GO:0042158"(lipoprotein biosynthetic process)|go:"GO:0042159"(lipoprotein catabolic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045540"(regulation of cholesterol biosynthetic process)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071379"(cellular response to prostaglandin stimulus)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR001747(Lipid transport protein, N-terminal)|interpro:IPR009454(Lipid transport, open beta-sheet)|interpro:IPR011030(Vitellinogen, superhelical)|interpro:IPR015255(Vitellinogen, open beta-sheet)|interpro:IPR015816(Vitellinogen, beta-sheet N-terminal)|interpro:IPR015819(Lipid transport protein, beta-sheet shell)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022176|mint:P04114|reactome:R-HSA-202733|reactome:R-HSA-3000471|reactome:R-HSA-3000480|reactome:R-HSA-3000484|reactome:R-HSA-3000497|reactome:R-HSA-381426|reactome:R-HSA-432142|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866423|reactome:R-HSA-8957275|reactome:R-HSA-8963888|reactome:R-HSA-8963901|reactome:R-HSA-8964026|reactome:R-HSA-8964038|reactome:R-HSA-8964041|reactome:R-HSA-5686938|reactome:R-HSA-8964046|reactome:R-HSA-9707616|reactome:R-HSA-975634|dip:DIP-44767N intact:EBI-710918(chain-parent) - - chain-seq-start:1712|chain-seq-end:1972 figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:2A4FraaZg1hHoxDkvi6DsKpoCD49606 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 intact-crc:8F1DF0474D266FA2|rigid:YWWchpHYdrKGuJvt9HCaBNegdpg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96EC8 uniprotkb:Q9WMX2-PRO_0000037550 intact:EBI-751210|uniprotkb:Q5JP08|uniprotkb:B4E1U7|uniprotkb:G5E997|ensembl:ENSP00000417573 intact:EBI-8853273 psi-mi:yipf6_human(display_long)|uniprotkb:YIP1 family member 6(gene name synonym)|uniprotkb:YIPF6(gene name)|psi-mi:YIPF6(display_short) psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083607|imex:IM-26075-69 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_776195.2|refseq:NP_001182143.1|ensembl:ENSG00000181704(gene)|ensembl:ENST00000462683(transcript)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0060576"(intestinal epithelial cell development)|interpro:IPR006977(Yip1 domain)|mint:Q96EC8|reactome:R-HSA-432722 intact:EBI-710918(chain-parent) - - chain-seq-start:1712|chain-seq-end:1972 figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:mfHkmdPyX5lK/euzg8v1Ydikf5w9606 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 intact-crc:DC0C41A7E206CEBE|rigid:9cLsnuyBiDgR2GdsrQabTyCeigE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P54851 uniprotkb:Q9WMX2-PRO_0000037550 intact:EBI-9083553|uniprotkb:B2R7V6|uniprotkb:D3DUF8|ensembl:ENSP00000352540|ensembl:ENSP00000445712 intact:EBI-8853273 psi-mi:emp2_human(display_long)|uniprotkb:EMP2(gene name)|psi-mi:EMP2(display_short)|uniprotkb:XMP(gene name synonym)|uniprotkb:Protein XMP(gene name synonym) psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083575|imex:IM-26075-85 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001415.1|refseq:XP_006720927.1|ensembl:ENSG00000213853(gene)|ensembl:ENST00000359543(transcript)|ensembl:ENST00000536829(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001913"(T cell mediated cytotoxicity)|go:"GO:0001952"(regulation of cell-matrix adhesion)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0003093"(regulation of glomerular filtration)|go:"GO:0005178"(integrin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007566"(embryo implantation)|go:"GO:0008219"(cell death)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010594"(regulation of endothelial cell migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032060"(bleb assembly)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0070252"(actin-mediated cell contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|go:"GO:2001212"(regulation of vasculogenesis)|interpro:IPR003933(Epithelial membrane protein EMP-2)|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|interpro:IPR004032(PMP-22/EMP/MP20) intact:EBI-710918(chain-parent) - - chain-seq-start:1712|chain-seq-end:1972 figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:EUVI+CwVw3JJidad+/TkmOBKEeo9606 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 intact-crc:C77842A7D33349E6|rigid:Z5aJRRGrA8gPkzkCSbZslhXz3Fk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8N6L1 uniprotkb:Q9WMX2-PRO_0000037550 intact:EBI-1053775|uniprotkb:Q86XW2|uniprotkb:Q8IWS4|uniprotkb:Q6PG45|uniprotkb:B2R4Q1|ensembl:ENSP00000295682 intact:EBI-8853273 psi-mi:ktap2_human(display_long)|uniprotkb:KRTCAP2(gene name)|psi-mi:KRTCAP2(display_short)|uniprotkb:KCP2(gene name synonym)|uniprotkb:Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit KCP2(gene name synonym) psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083548|imex:IM-26075-67 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_776251.1|ensembl:ENSG00000163463(gene)|ensembl:ENST00000295682(transcript)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042543"(protein N-linked glycosylation via arginine)|interpro:IPR018614 intact:EBI-710918(chain-parent) - - chain-seq-start:1712|chain-seq-end:1972 figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:UV1w5dUgiiefNipBAMcEKj/WMIY9606 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 intact-crc:AA3E798EF5A12FA0|rigid:vPz6FIFI43ONR1EJ1El52HWmHjw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9P0B6 uniprotkb:Q9WMX2-PRO_0000037550 intact:EBI-9083477|uniprotkb:Q5T7F7|uniprotkb:Q9BTQ9|ensembl:ENSP00000362507 intact:EBI-8853273 psi-mi:cc167_human(display_long)|uniprotkb:CCDC167(gene name)|psi-mi:CCDC167(display_short)|uniprotkb:C6orf129(gene name synonym)|uniprotkb:HSPC265(orf name) psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083475|imex:IM-26075-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_612502.1|ensembl:ENSG00000198937(gene)|ensembl:ENST00000373408(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR028194 intact:EBI-710918(chain-parent) - - chain-seq-start:1712|chain-seq-end:1972 figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:el6K1I4AQwH3OgjfL0EgIJmQjVc9606 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 intact-crc:B7AC025C4B2392F7|rigid:OMYzQNGVYyD1fKRTBWMWswykEG8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O96005 uniprotkb:Q9WMX2-PRO_0000037550 intact:EBI-2873194|ensembl:ENSP00000336994|uniprotkb:Q53ET6|uniprotkb:Q9BSS5|uniprotkb:B3KQH2|uniprotkb:B4DDS3|uniprotkb:B4E2X9|uniprotkb:B7Z9X9|uniprotkb:F5H8J3 intact:EBI-8853273 psi-mi:clpt1_human(display_long)|uniprotkb:CLPTM1(gene name)|psi-mi:CLPTM1(display_short) psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083463|imex:IM-26075-47 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000104853(gene)|ensembl:ENST00000337392(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007275"(multicellular organism development)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0033081"(regulation of T cell differentiation in thymus)|interpro:IPR008429(Cleft lip and palate transmembrane 1)|interpro:IPR030434|mint:O96005|refseq:NP_001285.1|refseq:NP_001269104.1|refseq:NP_001269105.1 intact:EBI-710918(chain-parent) - - chain-seq-start:1712|chain-seq-end:1972 figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:CFQ2o5QzCYtIDaxlVtJlA6FEMgU9606 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 intact-crc:790928DE68ABEF0C|rigid:TfoUtCgBJ/nOLRMbVEMFpnJ4Rig false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15084 uniprotkb:Q9WMX2-PRO_0000037550 intact:EBI-1043087|uniprotkb:Q6ZSH5|ensembl:ENSP00000272227|uniprotkb:B3KY95|uniprotkb:B5MCQ5|uniprotkb:B7Z4M8|uniprotkb:F8WA83|uniprotkb:B7Z254|uniprotkb:Q99778|uniprotkb:Q53RC7 intact:EBI-8853273 psi-mi:pdia6_human(display_long)|uniprotkb:PDIA6(gene name)|psi-mi:PDIA6(display_short)|uniprotkb:TXNDC7(gene name synonym)|uniprotkb:Protein disulfide isomerase P5(gene name synonym)|uniprotkb:Thioredoxin domain-containing protein 7(gene name synonym)|uniprotkb:ERP5(gene name synonym)|uniprotkb:P5(gene name synonym)|uniprotkb:Endoplasmic reticulum protein 5(gene name synonym) psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083435|imex:IM-26075-45 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001269633.1|refseq:NP_001269634.1|refseq:NP_001269635.1|refseq:NP_001269636.1|interpro:IPR036249|interpro:IPR044569|mint:Q15084|rcsb pdb:1X5D|rcsb pdb:3VWW|rcsb pdb:3W8J|rcsb pdb:4EF0|rcsb pdb:4GWR|reactome:R-HSA-381038|reactome:R-HSA-381426|reactome:R-HSA-8957275|interpro:IPR017937|ensembl:ENSG00000143870(gene)|ensembl:ENST00000272227(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0042470"(melanosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|refseq:NP_005733.1 intact:EBI-710918(chain-parent) - - chain-seq-start:1712|chain-seq-end:1972 figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:411bo7TdfeCtMvUqyBb7bofi5To9606 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 intact-crc:FD2DFF527ACC6E52|rigid:ibFtpCXXHGlnr4eFrRPPk4ASwUU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9WMX2-PRO_0000037550 uniprotkb:P05182 intact:EBI-8853273 intact:EBI-9083494|ensembl:ENSRNOP00000016883 psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:cp2e1_rat(display_long)|uniprotkb:Cyp2e1(gene name)|psi-mi:Cyp2e1(display_short)|uniprotkb:Cyp2e(gene name synonym)|uniprotkb:Cyp2e-1(gene name synonym)|uniprotkb:4-nitrophenol 2-hydroxylase(gene name synonym)|uniprotkb:CYPIIE1(gene name synonym)|uniprotkb:Cytochrome P450-J(gene name synonym)|uniprotkb:Cytochrome P450RLM6(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083492|imex:IM-26075-101 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-710918(chain-parent) rgd:2475|refseq:NP_113731.1|ensembl:ENSRNOG00000012458(gene)|ensembl:ENSRNOT00000016883(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002933"(lipid hydroxylation)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006082"(organic acid metabolic process)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0008202"(steroid metabolic process)|go:"GO:0008392"(arachidonic acid epoxygenase activity)|go:"GO:0008395"(steroid hydroxylase activity)|go:"GO:0009617"(response to bacterium)|go:"GO:0010193"(response to ozone)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0016098"(monoterpenoid metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0017144"|go:"GO:0018601"(4-nitrophenol 2-monooxygenase activity)|go:"GO:0018960"(4-nitrophenol metabolic process)|go:"GO:0019373"(epoxygenase P450 pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0020037"(heme binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031227"(intrinsic component of endoplasmic reticulum membrane)|go:"GO:0042493"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045471"(response to ethanol)|go:"GO:0046483"(heterocycle metabolic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070330"(aromatase activity)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002401(Cytochrome P450, E-class, group I)|interpro:IPR008070(Cytochrome P450, E-class, group I, CYP2E-like)|interpro:IPR017972|interpro:IPR036396|reactome:R-RNO-211981|reactome:R-RNO-211999|reactome:R-RNO-9027307|go:"GO:0042738" - chain-seq-start:1712|chain-seq-end:1972 - figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 rogid:6UhiJFBVhoheezfhAtoRhzGyaC410116 intact-crc:0537E558767BD603|rigid:htnr2GBAj3lLplrTyoq/Lx364zU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15388 uniprotkb:Q9WMX2-PRO_0000037541 intact:EBI-711636|uniprotkb:A8K195|uniprotkb:Q498B3|uniprotkb:Q6IBT4|ensembl:ENSP00000355566 intact:EBI-6863754 psi-mi:tom20_human(display_long)|uniprotkb:Outer mitochondrial membrane receptor Tom20(gene name synonym)|uniprotkb:TOMM20(gene name)|psi-mi:TOMM20(display_short)|uniprotkb:KIAA0016(gene name synonym)|uniprotkb:Mitochondrial 20 kDa outer membrane protein(gene name synonym) psi-mi:q9wmx2-pro_0000037541(display_long) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083427|imex:IM-26075-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055580.1|dip:DIP-46735N|ensembl:ENSG00000173726(gene)|ensembl:ENST00000366607(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016031"(tRNA import into mitochondrion)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030943"(mitochondrion targeting sequence binding)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1905242"(response to 3,3',5-triiodo-L-thyronine)|interpro:IPR002056(Protein import receptor MAS20)|interpro:IPR022422|interpro:IPR023392|rcsb pdb:4APO|reactome:R-HSA-1268020|reactome:R-HSA-5205685|reactome:R-HSA-5689880 intact:EBI-710918(chain-parent) - - chain-seq-start:2|chain-seq-end:191 figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:+wNh1qTU0NtgQekYJjhfj6O3UoA9606 rogid:zS2NVHBt5ng21TAtWlc6Q0daM5g333284 intact-crc:CE356824F310D458|rigid:6JFZCho8e+tfUJCW7GCHzk73opk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9WMX2-PRO_0000037541 uniprotkb:Q8TCT9 intact:EBI-6863754 intact:EBI-347472|uniprotkb:Q540H8|uniprotkb:Q5JWP2|uniprotkb:Q5JWP3|uniprotkb:Q5JWP4|uniprotkb:Q5JWP5|uniprotkb:Q7Z4F2|uniprotkb:Q86Y35|uniprotkb:Q95H87|uniprotkb:Q9H110|uniprotkb:Q9H111|uniprotkb:Q15K36|uniprotkb:B2RAY5|uniprotkb:E1P5L3|ensembl:ENSP00000343032 psi-mi:q9wmx2-pro_0000037541(display_long) psi-mi:hm13_human(display_long)|uniprotkb:HM13(gene name)|psi-mi:HM13(display_short)|uniprotkb:H13(gene name synonym)|uniprotkb:PSL3(gene name synonym)|uniprotkb:SPP(gene name synonym)|uniprotkb:Signal peptide peptidase(gene name synonym)|uniprotkb:Presenilin-like protein 3(gene name synonym)|uniprotkb:Intramembrane protease 1(gene name synonym)|uniprotkb:IMP1(gene name synonym)|uniprotkb:MSTP086(orf name) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083382|imex:IM-26075-43 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-710918(chain-parent) refseq:NP_110416.1|refseq:NP_848695.1|refseq:NP_848696.1|refseq:NP_848697.1|ensembl:ENSG00000101294(gene)|ensembl:ENST00000340852(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006465"(signal peptide processing)|go:"GO:0008233"(peptidase activity)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033619"(membrane protein proteolysis)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0042500"(aspartic endopeptidase activity, intramembrane cleaving)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0061960"(regulation of heme oxygenase activity)|go:"GO:0071458"(integral component of cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:1904211"(membrane protein proteolysis involved in retrograde protein transport, ER to cytosol)|interpro:IPR006639(Peptidase A22, presenilin signal peptide)|interpro:IPR007369(Peptidase A22B, signal peptide peptidase)|reactome:R-HSA-9707587 - chain-seq-start:2|chain-seq-end:191 - figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:zS2NVHBt5ng21TAtWlc6Q0daM5g333284 rogid:DxNjJDcc+zomfXAj0TEaByKeNqc9606 intact-crc:9D07EE54DC85570B|rigid:hiQc1fLrpcZCaMHIgAiULIY8ZNA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9WMX2-PRO_0000037550 uniprotkb:P00167 intact:EBI-8853273 intact:EBI-1047284|uniprotkb:A8MV91|uniprotkb:Q6IB14|uniprotkb:F8WEU4|ensembl:ENSP00000341625 psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:cyb5_human(display_long)|uniprotkb:CYB5A(gene name)|psi-mi:CYB5A(display_short)|uniprotkb:CYB5(gene name synonym)|uniprotkb:Microsomal cytochrome b5 type A(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083471|imex:IM-26075-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-710918(chain-parent) refseq:NP_001905.1|refseq:NP_683725.1|refseq:XP_011524137.1|refseq:NP_001177736.1|go:"GO:0005829"(cytosol)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0020037"(heme binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046872"(metal ion binding)|interpro:IPR001199(Cytochrome b5)|interpro:IPR018506|interpro:IPR036400|rcsb pdb:2I96|reactome:R-HSA-196836|reactome:R-HSA-9609523|ensembl:ENSG00000166347(gene)|ensembl:ENST00000340533(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane) - chain-seq-start:1712|chain-seq-end:1972 - figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 rogid:nZ/xafhkGjHBGCIWhtvBD1mtVSQ9606 intact-crc:6DE95E02BC078DD2|rigid:hnkfagHiCtUk9c1kvFwCVo5J1a4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9WMX2-PRO_0000037550 uniprotkb:Q15166 intact:EBI-8853273 intact:EBI-6677114|ensembl:ENSP00000265627|uniprotkb:A4D1H8|uniprotkb:O75855|uniprotkb:O76060|uniprotkb:Q6IRU9|uniprotkb:Q8IX97|uniprotkb:Q9BZH9 psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:pon3_human(display_long)|uniprotkb:PON3(gene name)|psi-mi:PON3(display_short) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083676|imex:IM-26075-107 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-710918(chain-parent) ensembl:ENSG00000105852(gene)|ensembl:ENST00000265627(transcript)|go:"GO:0004063"(aryldialkylphosphatase activity)|go:"GO:0004064"(arylesterase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0010124"(phenylacetate catabolic process)|go:"GO:0018733"(3,4-dihydrocoumarin hydrolase activity)|go:"GO:0019439"(aromatic compound catabolic process)|go:"GO:0032929"(negative regulation of superoxide anion generation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046226"(coumarin catabolic process)|go:"GO:0046395"(carboxylic acid catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0102007"(acyl-L-homoserine-lactone lactonohydrolase activity)|go:"GO:0009636"(response to toxic substance)|interpro:IPR002640(Arylesterase)|interpro:IPR008364(Paraoxonase2)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|reactome:R-HSA-2142688|refseq:NP_000931.1 - chain-seq-start:1712|chain-seq-end:1972 - figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 rogid:KzyA/Zs/1Tn8fmsUChooqHJNM3M9606 intact-crc:B88E6A61221E94A5|rigid:4BfZ3Y34S/gUJ1sxkF5jrDq0rK4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9WMX2-PRO_0000037541 uniprotkb:O75306 intact:EBI-6863754 intact:EBI-1224806|uniprotkb:Q5VTW0|uniprotkb:Q969P3|uniprotkb:Q9UEV3|uniprotkb:J3KPM7|uniprotkb:D3DVG7|intact:EBI-11120296|intact:EBI-28971126|ensembl:ENSP00000356972|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENSP00000504199|ensembl:ENSP00000504846 psi-mi:q9wmx2-pro_0000037541(display_long) psi-mi:ndus2_human(display_long)|uniprotkb:NDUFS2(gene name)|psi-mi:NDUFS2(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 49 kDa subunit(gene name synonym)|uniprotkb:Complex I-49kD(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083354|imex:IM-26075-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-710918(chain-parent) ensembl:ENSP00000356972|ensembl:ENST00000392179|ensembl:ENSP00000376018|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENST00000677457|ensembl:ENSP00000503294|ensembl:ENST00000677550|ensembl:ENSP00000503353|ensembl:ENSP00000504199|ensembl:ENSP00000504846|ensembl:ENST00000678605|ensembl:ENSP00000503969|ensembl:ENST00000679176|ensembl:ENSP00000504170|refseq:NP_001159631.1|refseq:NP_004541.1|refseq:XP_005245265.1|refseq:XP_016856846.1|ensembl:ENST00000676600(transcript)|ensembl:ENST00000676972(transcript)|ensembl:ENST00000678507(transcript)|ensembl:ENST00000678511(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042063"(gliogenesis)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|ensembl:ENST00000367993(transcript)|go:"GO:0048038"(quinone binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0071453"(cellular response to oxygen levels)|interpro:IPR001135(NADH-ubiquinone oxidoreductase, chain 49kDa)|interpro:IPR014029(NADH-ubiquinone oxidoreductase, chain 49kDa, conserved site)|interpro:IPR022885|interpro:IPR029014|mint:O75306|rcsb pdb:5XTB|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|ensembl:ENSG00000158864(gene) - chain-seq-start:2|chain-seq-end:191 - figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:zS2NVHBt5ng21TAtWlc6Q0daM5g333284 rogid:ZyGea/CEJ7g/u+3D7SXTtLUAnRY9606 intact-crc:FE06FFEE6C9565B7|rigid:j6MP/8vyFSzZUiGhqhL0B3lMIjk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P05141 uniprotkb:Q9WMX2-PRO_0000037541 intact:EBI-355133|uniprotkb:O43350|uniprotkb:B2RCV1|ensembl:ENSP00000360671 intact:EBI-6863754 psi-mi:adt2_human(display_long)|uniprotkb:SLC25A5(gene name)|psi-mi:SLC25A5(display_short)|uniprotkb:ANT2(gene name synonym)|uniprotkb:Adenine nucleotide translocator 2(gene name synonym)|uniprotkb:ADP,ATP carrier protein 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 5(gene name synonym)|uniprotkb:ADP,ATP carrier protein, fibroblast isoform(gene name synonym)|uniprotkb:AAC2(gene name synonym) psi-mi:q9wmx2-pro_0000037541(display_long) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083350|imex:IM-26075-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001143.2|reactome:R-HSA-83936|reactome:R-HSA-180897|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045121"(membrane raft)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0051503"(adenine nucleotide transport)|go:"GO:0071817"(MMXD complex)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P05141|go:"GO:0005739"(mitochondrion)|ensembl:ENSG00000005022(gene)|ensembl:ENST00000317881(transcript)|go:"GO:0000295"(adenine nucleotide transmembrane transporter activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|dip:DIP-33873N intact:EBI-710918(chain-parent) - - chain-seq-start:2|chain-seq-end:191 figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:8b4IQKtL2FJG/MS/5+mJUJrggYc9606 rogid:zS2NVHBt5ng21TAtWlc6Q0daM5g333284 intact-crc:4EAC8A89A55DA618|rigid:bkf1C+/WPOx4rn5em66WHYWAtOc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P02792 uniprotkb:Q9WMX2-PRO_0000037541 intact:EBI-713279|uniprotkb:Q7Z2W1|uniprotkb:Q9BTZ8|ensembl:ENSP00000366525|uniprotkb:B2R4B9|uniprotkb:Q6IBT7|uniprotkb:Q86WI9|uniprotkb:Q8WU07|uniprotkb:Q96AU9|uniprotkb:Q96CU0 intact:EBI-6863754 psi-mi:fril_human(display_long)|uniprotkb:FTL(gene name)|psi-mi:FTL(display_short) psi-mi:q9wmx2-pro_0000037541(display_long) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083338|imex:IM-26075-63 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000137.2|ensembl:ENSG00000087086(gene)|ensembl:ENST00000331825(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006880"(intracellular sequestering of iron ion)|go:"GO:0008043"(intracellular ferritin complex)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008199"(ferric iron binding)|go:"GO:0016020"(membrane)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0044754"(autolysosome)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001519(Ferritin, N-terminal)|interpro:IPR008331(Ferritin and Dps)|interpro:IPR009040(Ferritin-like)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR012347(Ferritin-related)|interpro:IPR014034(Ferritin, conserved site)|mint:P02792|rcsb pdb:2FFX|rcsb pdb:2FG4|rcsb pdb:2FG8|rcsb pdb:3KXU|rcsb pdb:4V6B|rcsb pdb:5LG8|rcsb pdb:6TR9|rcsb pdb:6TS0|rcsb pdb:6TS1|rcsb pdb:6TSA|rcsb pdb:6TSF|rcsb pdb:6TSJ|rcsb pdb:6WX6|reactome:R-HSA-3000480|reactome:R-HSA-432722|reactome:R-HSA-6798695|reactome:R-HSA-917937|dip:DIP-31248N intact:EBI-710918(chain-parent) - - chain-seq-start:2|chain-seq-end:191 figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:+mbnoETQ9TuBZg8Gc09nwAjwKTE9606 rogid:zS2NVHBt5ng21TAtWlc6Q0daM5g333284 intact-crc:53971E543335523D|rigid:r0aQyWj6iViI3n8Lmbk0GKT/A2o false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9WMX2-PRO_0000037541 uniprotkb:P38117 intact:EBI-6863754 intact:EBI-1056543|uniprotkb:Q6IBH7|uniprotkb:Q71RF6|uniprotkb:Q9Y3S7|uniprotkb:B3KNY2|uniprotkb:A8K766|ensembl:ENSP00000311930 psi-mi:q9wmx2-pro_0000037541(display_long) psi-mi:etfb_human(display_long)|uniprotkb:ETFB(gene name)|psi-mi:ETFB(display_short)|uniprotkb:FP585(orf name) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083334|imex:IM-26075-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-710918(chain-parent) refseq:NP_001014763.1|refseq:NP_001976.1|dip:DIP-6162N|ensembl:ENSG00000105379(gene)|ensembl:ENST00000309244(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009055"(electron transfer activity)|go:"GO:0033539"(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|interpro:IPR000049(Electron transfer flavoprotein, beta-subunit, core)|interpro:IPR012255(Electron transfer flavoprotein, beta subunit)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR014730(Electron transfer flavoprotein, alpha/beta-subunit, N-terminal)|interpro:IPR033948|rcsb pdb:1EFV|rcsb pdb:1T9G|rcsb pdb:2A1T|rcsb pdb:2A1U|reactome:R-HSA-611105|reactome:R-HSA-8876725 - chain-seq-start:2|chain-seq-end:191 - figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:zS2NVHBt5ng21TAtWlc6Q0daM5g333284 rogid:Fip+C+sJJhYoSZXwU/FZvabPAEY9606 intact-crc:7F346CD7BD947924|rigid:niPN0ouYxsOxc17k0a4OVL/mM0Y false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9WMX2-PRO_0000037541 uniprotkb:P47813 intact:EBI-6863754 intact:EBI-1045377|uniprotkb:Q0VGC2|uniprotkb:Q5JPS5|uniprotkb:Q5JPS6|uniprotkb:B2R5U5|ensembl:ENSP00000368927 psi-mi:q9wmx2-pro_0000037541(display_long) psi-mi:if1ax_human(display_long)|uniprotkb:Eukaryotic translation initiation factor 4C(gene name synonym)|uniprotkb:EIF1AX(gene name)|psi-mi:EIF1AX(display_short)|uniprotkb:EIF1A(gene name synonym)|uniprotkb:EIF4C(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083318|imex:IM-26075-41 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-710918(chain-parent) refseq:NP_001403.1|ensembl:ENSG00000173674(gene)|ensembl:ENST00000379607(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006413"(translational initiation)|go:"GO:0008135"(translation factor activity, RNA binding)|interpro:IPR001253("Eukaryotic initiation factor 1A (eIF-1A)")|interpro:IPR006196(S1, IF1 type)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018104|rcsb pdb:1D7Q|rcsb pdb:3ZJY|rcsb pdb:4KZY|rcsb pdb:4KZZ|rcsb pdb:6YBW|rcsb pdb:6ZMW|rcsb pdb:6ZP4|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:XP_016855198.1|dip:DIP-40995N - chain-seq-start:2|chain-seq-end:191 - figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:zS2NVHBt5ng21TAtWlc6Q0daM5g333284 rogid:C/YFiphF76YhqKYoM7ybw320ihw9606 intact-crc:FFC5B9872415FF51|rigid:OONOoMJEMajAnO5kjvLAF8fO7BE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P01009 uniprotkb:Q9WMX2-PRO_0000037550 intact:EBI-986224|uniprotkb:Q7M4R2|uniprotkb:Q86U18|uniprotkb:Q86U19|uniprotkb:Q96BF9|uniprotkb:Q96ES1|uniprotkb:Q9P1P0|uniprotkb:A6PX14|uniprotkb:Q0PVP5|uniprotkb:Q13672|uniprotkb:Q53XB8|uniprotkb:Q5U0M1|uniprotkb:B2RDQ8|uniprotkb:Q9UCE6|uniprotkb:Q9UCM3|ensembl:ENSP00000348068|ensembl:ENSP00000376802|ensembl:ENSP00000376803|ensembl:ENSP00000385960|ensembl:ENSP00000390299|ensembl:ENSP00000408474|ensembl:ENSP00000416066|ensembl:ENSP00000416354|ensembl:ENSP00000490054 intact:EBI-8853273 psi-mi:a1at_human(display_long)|uniprotkb:Alpha-1 protease inhibitor(gene name synonym)|uniprotkb:Alpha-1-antiproteinase(gene name synonym)|uniprotkb:AAT(gene name synonym)|uniprotkb:PI(gene name synonym)|uniprotkb:PRO0684(orf name)|uniprotkb:PRO2209(orf name)|uniprotkb:SERPINA1(gene name)|psi-mi:SERPINA1(display_short)|uniprotkb:Serpin A1(gene name synonym) psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083749|imex:IM-26075-59 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000286.3|refseq:NP_001002235.1|refseq:NP_001002236.1|refseq:NP_001121172.1|refseq:NP_001121173.1|refseq:NP_001121174.1|refseq:NP_001121175.1|refseq:NP_001121176.1|refseq:NP_001121177.1|refseq:NP_001121178.1|refseq:NP_001121179.1|refseq:XP_016876859.1|dip:DIP-35493N|ensembl:ENSG00000197249(gene)|ensembl:ENST00000355814(transcript)|ensembl:ENST00000393087(transcript)|ensembl:ENST00000393088(transcript)|ensembl:ENST00000404814(transcript)|ensembl:ENST00000437397(transcript)|ensembl:ENST00000440909(transcript)|ensembl:ENST00000448921(transcript)|ensembl:ENST00000449399(transcript)|ensembl:ENST00000636712(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006953"(acute-phase response)|go:"GO:0007596"(blood coagulation)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P01009|rcsb pdb:1ATU|rcsb pdb:1EZX|rcsb pdb:1HP7|rcsb pdb:1D5S|rcsb pdb:1IZ2|rcsb pdb:1KCT|rcsb pdb:1OO8|rcsb pdb:1OPH|rcsb pdb:1PSI|rcsb pdb:1QLP|rcsb pdb:1QMB|rcsb pdb:2D26|rcsb pdb:2QUG|rcsb pdb:3CWL|rcsb pdb:3CWM|rcsb pdb:3DRM|rcsb pdb:3DRU|rcsb pdb:3NDD|rcsb pdb:3NDF|rcsb pdb:3NE4|rcsb pdb:3T1P|rcsb pdb:4PYW|rcsb pdb:5IO1|rcsb pdb:5NBU|rcsb pdb:5NBV|rcsb pdb:6HX4|rcsb pdb:6I4V|rcsb pdb:6I7U|rcsb pdb:6IAY|rcsb pdb:6ROD|rcsb pdb:7AEL|rcsb pdb:7API|rcsb pdb:7NPK|rcsb pdb:7NPL|rcsb pdb:8API|rcsb pdb:9API|reactome:R-HSA-114608|reactome:R-HSA-204005|reactome:R-HSA-381426|reactome:R-HSA-5694530|reactome:R-HSA-6798695|reactome:R-HSA-8957275 intact:EBI-710918(chain-parent) - - chain-seq-start:1712|chain-seq-end:1972 figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:eIbjQWRWsWv+B28IcSUIKJ+Eros9606 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 intact-crc:5160C7D79F812B6E|rigid:1XUopw5B6LsfUbBaiP9Tx9qS2O0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9WMX2-PRO_0000037550 uniprotkb:Q08830 intact:EBI-8853273 intact:EBI-3934830|uniprotkb:Q4PJH9|uniprotkb:Q96KW6|uniprotkb:A6NKU4|uniprotkb:Q96QM6|uniprotkb:Q53YF1|ensembl:ENSP00000371262|ensembl:ENSP00000371263|ensembl:ENSP00000381131|ensembl:ENSP00000381133|ensembl:ENSP00000401952|ensembl:ENSP00000428430|ensembl:ENSP00000429757|uniprotkb:Q8NG32 psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:fgl1_human(display_long)|uniprotkb:FGL1(gene name)|psi-mi:FGL1(display_short)|uniprotkb:HFREP1(gene name synonym)|uniprotkb:HP-041(gene name synonym)|uniprotkb:Hepassocin(gene name synonym)|uniprotkb:Hepatocyte-derived fibrinogen-related protein 1(gene name synonym)|uniprotkb:Liver fibrinogen-related protein 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083595|imex:IM-26075-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-710918(chain-parent) ensembl:ENSG00000104760(gene)|ensembl:ENST00000381840(transcript)|ensembl:ENST00000381841(transcript)|ensembl:ENST00000398054(transcript)|ensembl:ENST00000398056(transcript)|ensembl:ENST00000427924(transcript)|ensembl:ENST00000518650(transcript)|ensembl:ENST00000522444(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005615"(extracellular space)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050868"(negative regulation of T cell activation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0072574"(hepatocyte proliferation)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|refseq:NP_004458.3|refseq:NP_671736.2|refseq:NP_963846.1|refseq:NP_963847.1|ensembl:ENSG00000104760|ensembl:ENSG00000104760|refseq:XP_016868721.1 - chain-seq-start:1712|chain-seq-end:1972 - figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 rogid:g6RetxaEJ0o78wFzw9oxEEGFI8M9606 intact-crc:9A66643D883DDD1C|rigid:B89lsuHWygSGFM0a2ctBP8wXpdI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P00734 uniprotkb:Q9WMX2-PRO_0000037550 intact:EBI-297094|ensembl:ENSP00000308541|uniprotkb:B2R7F7|uniprotkb:B4E1A7|uniprotkb:Q4QZ40|uniprotkb:Q53H04|uniprotkb:Q53H06|uniprotkb:Q7Z7P3|uniprotkb:Q9UCA1|uniprotkb:Q69EZ7 intact:EBI-8853273 psi-mi:thrb_human(display_long)|uniprotkb:F2(gene name)|psi-mi:F2(display_short)|uniprotkb:Coagulation factor II(gene name synonym) psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083581|imex:IM-26075-49 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1BTH|rcsb pdb:1C1U|rcsb pdb:1C1V|rcsb pdb:1C1W|rcsb pdb:1C4U|rcsb pdb:1C4V|rcsb pdb:1C4Y|rcsb pdb:1C5L|rcsb pdb:1C5N|rcsb pdb:1C5O|rcsb pdb:1CA8|rcsb pdb:1D3D|rcsb pdb:1D3P|rcsb pdb:1D3Q|rcsb pdb:1D3T|rcsb pdb:1D4P|rcsb pdb:1D6W|rcsb pdb:1BMN|rcsb pdb:1D9I|rcsb pdb:1DE7|rcsb pdb:1DIT|rcsb pdb:1DM4|rcsb pdb:1DOJ|rcsb pdb:1DWB|rcsb pdb:1DWC|rcsb pdb:1DWD|rcsb pdb:1LHF|rcsb pdb:1LHG|rcsb pdb:1MH0|rcsb pdb:1MU6|rcsb pdb:1MU8|rcsb pdb:1MUE|rcsb pdb:1NM6|rcsb pdb:1NO9|rcsb pdb:1NRN|rcsb pdb:1NRO|rcsb pdb:1NRP|rcsb pdb:1NRQ|rcsb pdb:1NRR|rcsb pdb:1NRS|rcsb pdb:1DWE|rcsb pdb:1NT1|rcsb pdb:1NU7|rcsb pdb:1NU9|rcsb pdb:1KTT|rcsb pdb:1LHC|rcsb pdb:1NY2|rcsb pdb:1NZQ|rcsb pdb:1LHD|rcsb pdb:1O0D|rcsb pdb:1O2G|rcsb pdb:1LHE|rcsb pdb:1O5G|rcsb pdb:1OOK|rcsb pdb:1OYT|rcsb pdb:1P8V|rcsb pdb:1PPB|rcsb pdb:1HAG|rcsb pdb:1HAH|rcsb pdb:1DX5|rcsb pdb:1E0F|rcsb pdb:1EB1|rcsb pdb:1HAI|rcsb pdb:1HAO|rcsb pdb:1EOJ|rcsb pdb:1EOL|rcsb pdb:1FPC|rcsb pdb:1FPH|rcsb pdb:1HAP|rcsb pdb:1HBT|rcsb pdb:1G30|rcsb pdb:1G32|rcsb pdb:1G37|rcsb pdb:1GHV|rcsb pdb:1HDT|rcsb pdb:1HGT|rcsb pdb:1GHW|rcsb pdb:1GHX|rcsb pdb:1GHY|rcsb pdb:1GJ4|rcsb pdb:1GJ5|rcsb pdb:1HLT|rcsb pdb:1HUT|rcsb pdb:1HXE|rcsb pdb:1HXF|rcsb pdb:1IHS|rcsb pdb:1IHT|rcsb pdb:1H8D|rcsb pdb:1H8I|rcsb pdb:1JMO|rcsb pdb:1JOU|rcsb pdb:1JWT|rcsb pdb:1K21|rcsb pdb:1K22|rcsb pdb:1KTS|ensembl:ENST00000311907(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006953"(acute-phase response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007596"(blood coagulation)|go:"GO:0008083"(growth factor activity)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009611"(response to wounding)|go:"GO:0010544"(negative regulation of platelet activation)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030168"(platelet activation)|go:"GO:0030193"(regulation of blood coagulation)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|ensembl:ENSG00000180210(gene)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051838"(cytolysis by host of symbiont cells)|go:"GO:0051918"(negative regulation of fibrinolysis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070053"(thrombospondin receptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070945"(neutrophil-mediated killing of gram-negative bacterium)|go:"GO:0072562"(blood microparticle)|go:"GO:0042730"(fibrinolysis)|go:"GO:0090218"(positive regulation of lipid kinase activity)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1900738"(positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR000001(Kringle)|rcsb pdb:1A3B|rcsb pdb:1A3E|interpro:IPR000294(Vitamin K-dependent carboxylation/gamma-carboxyglutamic region)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003966(Peptidase S1A, prothrombin/thrombin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|rcsb pdb:1A46|rcsb pdb:1A4W|interpro:IPR018056|rcsb pdb:1A5G|rcsb pdb:1A61|rcsb pdb:1ABI|interpro:IPR018114|interpro:IPR018992|interpro:IPR033116|rcsb pdb:1ABJ|rcsb pdb:1AD8|interpro:IPR035972|rcsb pdb:1AE8|rcsb pdb:1AFE|rcsb pdb:1AHT|rcsb pdb:1AI8|rcsb pdb:1AIX|rcsb pdb:1AWF|rcsb pdb:1AWH|rcsb pdb:1AY6|interpro:IPR037111|rcsb pdb:1B5G|rcsb pdb:1B7X|rcsb pdb:1BA8|rcsb pdb:1BB0|rcsb pdb:1BCU|interpro:IPR038178|rcsb pdb:1BHX|interpro:IPR043504|mint:P00734|rcsb pdb:1BMM|rcsb pdb:1A2C|rcsb pdb:2ZI2|rcsb pdb:2ZIQ|rcsb pdb:2ZNK|rcsb pdb:2ZO3|rcsb pdb:3B23|rcsb pdb:2ZHW|rcsb pdb:3B9F|rcsb pdb:3BEF|rcsb pdb:3BEI|rcsb pdb:3BF6|rcsb pdb:3BIU|rcsb pdb:3BIV|rcsb pdb:3BV9|rcsb pdb:3C1K|rcsb pdb:3C27|rcsb pdb:3D49|rcsb pdb:3DA9|rcsb pdb:3DD2|rcsb pdb:3DHK|rcsb pdb:3DT0|rcsb pdb:3DUX|rcsb pdb:3E6P|rcsb pdb:3EE0|rcsb pdb:3EGK|rcsb pdb:3EQ0|rcsb pdb:3F68|rcsb pdb:3GIC|rcsb pdb:3GIS|rcsb pdb:3HAT|rcsb pdb:3HKJ|rcsb pdb:3HTC|rcsb pdb:3JZ1|rcsb pdb:3JZ2|rcsb pdb:3K65|rcsb pdb:3LDX|rcsb pdb:3LU9|rcsb pdb:3NXP|rcsb pdb:3P17|rcsb pdb:3P6Z|rcsb pdb:3P70|rcsb pdb:3PMH|rcsb pdb:3PO1|rcsb pdb:3QDZ|rcsb pdb:3QGN|rcsb pdb:3QLP|rcsb pdb:3QTO|rcsb pdb:3QTV|rcsb pdb:3QWC|rcsb pdb:3QX5|rcsb pdb:1QBV|rcsb pdb:1QHR|rcsb pdb:1QJ1|rcsb pdb:1QJ6|rcsb pdb:1TB6|rcsb pdb:1QJ7|rcsb pdb:1QUR|rcsb pdb:1RD3|rcsb pdb:1TBZ|rcsb pdb:1RIW|rcsb pdb:1THP|rcsb pdb:1THR|rcsb pdb:1THS|rcsb pdb:1SB1|rcsb pdb:1SFQ|rcsb pdb:1SG8|rcsb pdb:1SGI|rcsb pdb:1SHH|rcsb pdb:1TMB|rcsb pdb:1SL3|rcsb pdb:1SR5|rcsb pdb:1T4U|rcsb pdb:1T4V|rcsb pdb:1TA2|rcsb pdb:1TMT|rcsb pdb:1TMU|rcsb pdb:1TOM|rcsb pdb:1TQ0|rcsb pdb:1TQ7|rcsb pdb:1TWX|rcsb pdb:1UMA|rcsb pdb:1UVS|rcsb pdb:1VR1|rcsb pdb:1VZQ|rcsb pdb:1W7G|rcsb pdb:1WAY|rcsb pdb:1WBG|rcsb pdb:1XM1|rcsb pdb:1XMN|rcsb pdb:1YPE|rcsb pdb:1YPG|rcsb pdb:1YPJ|rcsb pdb:1YPK|rcsb pdb:1YPL|rcsb pdb:1TA6|rcsb pdb:1YPM|rcsb pdb:1Z71|rcsb pdb:2AFQ|rcsb pdb:2ANK|rcsb pdb:2ANM|rcsb pdb:2B5T|rcsb pdb:2BDY|rcsb pdb:2BVR|rcsb pdb:2BVS|rcsb pdb:2BVX|rcsb pdb:2BXT|rcsb pdb:2BXU|rcsb pdb:2C8W|rcsb pdb:2C8X|rcsb pdb:2C8Y|rcsb pdb:2C8Z|rcsb pdb:2C90|rcsb pdb:2C93|rcsb pdb:2CF8|rcsb pdb:2CF9|rcsb pdb:1Z8I|rcsb pdb:2CN0|rcsb pdb:2FEQ|rcsb pdb:1Z8J|rcsb pdb:1ZGI|rcsb pdb:1ZGV|rcsb pdb:1ZRB|rcsb pdb:2A0Q|rcsb pdb:2A2X|rcsb pdb:2FES|rcsb pdb:2GDE|rcsb pdb:2GP9|rcsb pdb:2A45|rcsb pdb:2H9T|rcsb pdb:2HGT|rcsb pdb:2HNT|rcsb pdb:2HPP|rcsb pdb:2HPQ|rcsb pdb:2HWL|rcsb pdb:3RLW|rcsb pdb:3RLY|rcsb pdb:3RM0|rcsb pdb:3R3G|rcsb pdb:3RM2|rcsb pdb:3RML|rcsb pdb:3RMM|rcsb pdb:3RMN|rcsb pdb:3RMO|rcsb pdb:3S7H|rcsb pdb:3S7K|rcsb pdb:3SHA|rcsb pdb:3SHC|rcsb pdb:3SI3|rcsb pdb:3SI4|rcsb pdb:3SQE|rcsb pdb:3SQH|rcsb pdb:3SV2|rcsb pdb:3T5F|rcsb pdb:3TU7|rcsb pdb:3U69|rcsb pdb:3U8O|rcsb pdb:3U8R|rcsb pdb:3U8T|rcsb pdb:3U98|rcsb pdb:3U9A|rcsb pdb:3UTU|rcsb pdb:3UWJ|rcsb pdb:3VXE|rcsb pdb:3VXF|rcsb pdb:4AX9|rcsb pdb:4AYV|rcsb pdb:4AYY|rcsb pdb:4AZ2|rcsb pdb:4BAH|rcsb pdb:4BAK|rcsb pdb:4BAM|rcsb pdb:4BAN|rcsb pdb:4BAO|rcsb pdb:4BAQ|rcsb pdb:4BOH|rcsb pdb:4CH2|rcsb pdb:4CH8|rcsb pdb:4DIH|rcsb pdb:4DII|rcsb pdb:4DT7|rcsb pdb:4DY7|rcsb pdb:4E05|rcsb pdb:4E7R|rcsb pdb:4H6S|rcsb pdb:4H6T|rcsb pdb:4HFP|rcsb pdb:4HTC|rcsb pdb:4HZH|rcsb pdb:4I7Y|rcsb pdb:4LOY|rcsb pdb:4LXB|rcsb pdb:4LZ1|rcsb pdb:4LZ4|rcsb pdb:4MLF|rcsb pdb:4NZQ|rcsb pdb:4O03|rcsb pdb:4RKJ|rcsb pdb:4RKO|rcsb pdb:4RN6|rcsb pdb:4THN|rcsb pdb:4UD9|rcsb pdb:4UDW|rcsb pdb:4UE7|rcsb pdb:4UEH|rcsb pdb:4UFD|rcsb pdb:4UFE|rcsb pdb:4UFF|rcsb pdb:4UFG|rcsb pdb:4YES|rcsb pdb:5A2M|rcsb pdb:5AF9|rcsb pdb:4E06|rcsb pdb:5AFY|rcsb pdb:5AHG|rcsb pdb:5CMX|rcsb pdb:5DO4|rcsb pdb:5E8E|rcsb pdb:5EDK|rcsb pdb:5EDM|rcsb pdb:5EW1|rcsb pdb:5EW2|rcsb pdb:5GDS|rcsb pdb:5GIM|rcsb pdb:5JDU|rcsb pdb:5JFD|rcsb pdb:5JZY|rcsb pdb:5L6N|rcsb pdb:5MJT|rcsb pdb:5MLS|rcsb pdb:5MM6|rcsb pdb:5NHU|rcsb pdb:5TO3|rcsb pdb:5Z5W|rcsb pdb:5Z5X|rcsb pdb:6BJR|rcsb pdb:6C2W|rcsb pdb:6EO6|rcsb pdb:6EO7|rcsb pdb:6EO8|rcsb pdb:6EO9|rcsb pdb:6V5T|rcsb pdb:7KME|rcsb pdb:8KME|reactome:R-HSA-140837|reactome:R-HSA-140875|reactome:R-HSA-159740|reactome:R-HSA-159763|reactome:R-HSA-159782|reactome:R-HSA-202733|reactome:R-HSA-375276|reactome:R-HSA-381426|reactome:R-HSA-416476|rcsb pdb:5AFZ|rcsb pdb:2JH5|rcsb pdb:2JH6|rcsb pdb:2OD3|rcsb pdb:2PGB|rcsb pdb:2PGQ|rcsb pdb:2PKS|rcsb pdb:2PW8|rcsb pdb:2R2M|rcsb pdb:2THF|rcsb pdb:2UUF|rcsb pdb:2UUJ|rcsb pdb:2UUK|rcsb pdb:2V3H|rcsb pdb:2V3O|rcsb pdb:2ZC9|rcsb pdb:2ZDA|rcsb pdb:2ZDV|rcsb pdb:2ZF0|rcsb pdb:2ZFF|rcsb pdb:2ZFP|rcsb pdb:2ZFQ|rcsb pdb:2ZFR|rcsb pdb:2ZG0|rcsb pdb:2JH0|rcsb pdb:2ZGB|rcsb pdb:2ZGX|rcsb pdb:2ZHE|rcsb pdb:2ZHF|rcsb pdb:2ZHQ|reactome:R-HSA-76009|reactome:R-HSA-9657688|reactome:R-HSA-9672391|reactome:R-HSA-977606|reactome:R-HSA-456926|refseq:NP_000497.1|refseq:NP_001298186.1|dip:DIP-6115N intact:EBI-710918(chain-parent) - - chain-seq-start:1712|chain-seq-end:1972 figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:f6OQ6v3WbFpxr7N6GhfZOHjSsTQ9606 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 intact-crc:0C7CE962F2AD5CC3|rigid:M8m4OVYiZO3+vIMZw5HXqzxx5U8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9WMX2-PRO_0000037550 uniprotkb:O95789 intact:EBI-8853273 intact:EBI-2514645|ensembl:ENSP00000349708|uniprotkb:Q9NWF1|uniprotkb:Q96IY0|uniprotkb:Q69YL4|uniprotkb:Q4G108|uniprotkb:Q32Q23|uniprotkb:B4DRJ6|uniprotkb:Q9P2J4|uniprotkb:Q5SVZ9|uniprotkb:Q5SW00 psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:zmym6_human(display_long)|uniprotkb:ZMYM6(gene name)|psi-mi:ZMYM6(display_short)|uniprotkb:KIAA1353(gene name synonym)|uniprotkb:ZNF258(gene name synonym)|uniprotkb:Zinc finger protein 258(gene name synonym)|uniprotkb:Buster2(gene name synonym)|uniprotkb:Transposon-derived Buster2 transposase-like protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tripathi et al. (2010) pubmed:20953506|imex:IM-26075 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9083733|imex:IM-26075-57 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-710918(chain-parent) ensembl:ENSG00000163867(gene)|ensembl:ENST00000357182(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0022604"(regulation of cell morphogenesis)|interpro:IPR010507(Zinc finger, MYM-type)|interpro:IPR011017(TRASH)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR025398|refseq:NP_009098.3 - chain-seq-start:1712|chain-seq-end:1972 - figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/06 2017/09/02 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 rogid:+g4Q8I50GP6Rhbptsd3A0ZMbuko9606 intact-crc:10254E4CBFD86436|rigid:doewYDPI0rMCXZWYv36apCRA2TY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)