#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9NTI2 uniprotkb:Q9NV96 intact:EBI-9539366|uniprotkb:Q9H527|uniprotkb:Q9NPU6|uniprotkb:Q9NTL2|uniprotkb:Q9NYM3|uniprotkb:Q6ZSP3|ensembl:ENSP00000371070 intact:EBI-2836942|uniprotkb:A8K9V8|uniprotkb:Q96H09|uniprotkb:Q9NSL9|uniprotkb:Q658Z3|uniprotkb:E1P539|ensembl:ENSP00000230461 psi-mi:at8a2_human(display_long)|uniprotkb:ATP8A2(gene name)|psi-mi:ATP8A2(display_short)|uniprotkb:ATPIB(gene name synonym)|uniprotkb:ATPase class I type 8A member 2(gene name synonym)|uniprotkb:ML-1(gene name synonym)|uniprotkb:P4-ATPase flippase complex alpha subunit ATP8A2(gene name synonym) psi-mi:cc50a_human(display_long)|uniprotkb:TMEM30A(gene name)|psi-mi:TMEM30A(display_short)|uniprotkb:C6orf67(gene name synonym)|uniprotkb:CDC50A(gene name synonym)|uniprotkb:Transmembrane protein 30A(gene name synonym)|uniprotkb:P4-ATPase flippase complex beta subunit TMEM30A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) van et al. (2010) imex:IM-22613|pubmed:20947505 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9539361|imex:IM-22613-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_005266476.1|refseq:NP_001300670.1|refseq:NP_057613.4|ensembl:ENSG00000132932(gene)|ensembl:ENST00000381655(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003011"(involuntary skeletal muscle contraction)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007409"(axonogenesis)|go:"GO:0007568"(aging)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010842"(retina layer formation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010996"(response to auditory stimulus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042755"(eating behavior)|go:"GO:0043588"(skin development)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0048666"(neuron development)|go:"GO:0050884"(neuromuscular process controlling posture)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0061092"(positive regulation of phospholipid translocation)|go:"GO:0090555"(phosphatidylethanolamine flippase activity)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140331"(aminophospholipid translocation)|go:"GO:0140346"(phosphatidylserine flippase activity)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|reactome:R-HSA-936837 refseq:NP_001137430.1|refseq:NP_060717.1|ensembl:ENSG00000112697(gene)|ensembl:ENST00000230461(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006855"(xenobiotic transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015247"(aminophospholipid flippase activity)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0061092"(positive regulation of phospholipid translocation)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR005045(Protein of unknown function DUF284, transmembrane eukaryotic)|interpro:IPR030351|mint:Q9NV96|rcsb pdb:6K7G|rcsb pdb:6K7H|rcsb pdb:6K7I|rcsb pdb:6K7J|rcsb pdb:6K7K|rcsb pdb:6K7M|rcsb pdb:6K7N|rcsb pdb:6LKN|rcsb pdb:7BSP|rcsb pdb:7BSQ|rcsb pdb:7BSS|rcsb pdb:7BSU|rcsb pdb:7BSV|rcsb pdb:7BSW|reactome:R-HSA-6798695|rcsb pdb:6K7L - - - figure legend:1F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2014/05/19 2018/09/18 rogid:8yFwrBfiZ3VYycp5AjHKdx9HKgg9606 rogid:HTSM+3ihZsx2qIRiNhutEb/Kyu09606 intact-crc:9FBD9AE364B58431|rigid:x40ib0/UzyY8tmyYIk4ejo6kpHA false tag:c-c v5 tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9Y2Q0 uniprotkb:Q9NV96 intact:EBI-9539324|uniprotkb:Q32M35|uniprotkb:Q32M36|uniprotkb:Q4W5J7|uniprotkb:Q4W5P2|ensembl:ENSP00000371084 intact:EBI-2836942|uniprotkb:A8K9V8|uniprotkb:Q96H09|uniprotkb:Q9NSL9|uniprotkb:Q658Z3|uniprotkb:E1P539|ensembl:ENSP00000230461 psi-mi:at8a1_human(display_long)|uniprotkb:ATP8A1(gene name)|psi-mi:ATP8A1(display_short)|uniprotkb:ATPIA(gene name synonym)|uniprotkb:ATPase class I type 8A member 1(gene name synonym)|uniprotkb:Chromaffin granule ATPase II(gene name synonym)|uniprotkb:P4-ATPase flippase complex alpha subunit ATP8A1(gene name synonym) psi-mi:cc50a_human(display_long)|uniprotkb:TMEM30A(gene name)|psi-mi:TMEM30A(display_short)|uniprotkb:C6orf67(gene name synonym)|uniprotkb:CDC50A(gene name synonym)|uniprotkb:Transmembrane protein 30A(gene name synonym)|uniprotkb:P4-ATPase flippase complex beta subunit TMEM30A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) van et al. (2010) imex:IM-22613|pubmed:20947505 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9539319|imex:IM-22613-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001098999.1|refseq:NP_006086.1|refseq:XP_016863134.1|ensembl:ENSG00000124406(gene)|ensembl:ENST00000381668(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0007612"(learning)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031090"(organelle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042584"(chromaffin granule membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0061092"(positive regulation of phospholipid translocation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140331"(aminophospholipid translocation)|go:"GO:0140346"(phosphatidylserine flippase activity)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:6K7G|rcsb pdb:6K7H|rcsb pdb:6K7I|rcsb pdb:6K7J|rcsb pdb:6K7K|rcsb pdb:6K7L|rcsb pdb:6K7M|rcsb pdb:6K7N|reactome:R-HSA-6798695|reactome:R-HSA-936837|go:"GO:0005783"(endoplasmic reticulum) refseq:NP_001137430.1|refseq:NP_060717.1|ensembl:ENSG00000112697(gene)|ensembl:ENST00000230461(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006855"(xenobiotic transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015247"(aminophospholipid flippase activity)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0061092"(positive regulation of phospholipid translocation)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR005045(Protein of unknown function DUF284, transmembrane eukaryotic)|interpro:IPR030351|mint:Q9NV96|rcsb pdb:6K7G|rcsb pdb:6K7H|rcsb pdb:6K7I|rcsb pdb:6K7J|rcsb pdb:6K7K|rcsb pdb:6K7M|rcsb pdb:6K7N|rcsb pdb:6LKN|rcsb pdb:7BSP|rcsb pdb:7BSQ|rcsb pdb:7BSS|rcsb pdb:7BSU|rcsb pdb:7BSV|rcsb pdb:7BSW|reactome:R-HSA-6798695|rcsb pdb:6K7L - - - figure legend:1E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2014/05/19 2014/10/16 rogid:dgEEryBicD80N5Kh567D+KQDV5g9606 rogid:HTSM+3ihZsx2qIRiNhutEb/Kyu09606 intact-crc:0CA500E4D704A94A|rigid:zMEkJn/3TvvyLf2+SHBevulmzXg false ha tag:c-c v5 tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q3MIR4 uniprotkb:P98198 intact:EBI-9527107|uniprotkb:B3KR84|uniprotkb:Q14D00|ensembl:ENSP00000450842 intact:EBI-9539266|uniprotkb:B4E3P4|uniprotkb:Q6NT69|uniprotkb:Q7Z486|uniprotkb:Q96I43|uniprotkb:Q96NQ7 psi-mi:cc50b_human(display_long)|uniprotkb:P4-ATPase flippase complex beta subunit TMEM30B(gene name synonym)|uniprotkb:TMEM30B(gene name)|psi-mi:TMEM30B(display_short)|uniprotkb:CDC50B(gene name synonym)|uniprotkb:Transmembrane protein 30B(gene name synonym) psi-mi:at8b2_human(display_long)|uniprotkb:ATP8B2(gene name)|psi-mi:ATP8B2(display_short)|uniprotkb:ATPID(gene name synonym)|uniprotkb:KIAA1137(gene name synonym)|uniprotkb:ATPase class I type 8B member 2(gene name synonym)|uniprotkb:P4-ATPase flippase complex alpha subunit ATP8B2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) van et al. (2010) imex:IM-22613|pubmed:20947505 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9539311|imex:IM-22613-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001017970.1|ensembl:ENSG00000182107(gene)|ensembl:ENST00000555868(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0015247"(aminophospholipid flippase activity)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|interpro:IPR005045(Protein of unknown function DUF284, transmembrane eukaryotic)|interpro:IPR030352 interpro:IPR023214|interpro:IPR030347|reactome:R-HSA-936837|interpro:IPR032630|interpro:IPR032631|interpro:IPR044492|interpro:IPR023299|interpro:IPR018303|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|refseq:NP_001005855.1|refseq:NP_065185.1|refseq:XP_005245412.1|interpro:IPR023298|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007030"(Golgi organization)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140345"(phosphatidylcholine flippase activity)|interpro:IPR036412 - - - figure legend:1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2014/05/19 2014/10/16 rogid:SEW0dE9gp2d2piEq/37EFUxcNOI9606 rogid:0qfmiw+yRBCQbBg9vx2Wzsmy53Y9606 intact-crc:652FA60D7473DDD3|rigid:LpwWqSvvYxH0XAlPUGLkdxbN/N0 false v5 tag:c-c ha tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P98198 uniprotkb:Q9NV96 intact:EBI-9539266|uniprotkb:B4E3P4|uniprotkb:Q6NT69|uniprotkb:Q7Z486|uniprotkb:Q96I43|uniprotkb:Q96NQ7 intact:EBI-2836942|uniprotkb:A8K9V8|uniprotkb:Q96H09|uniprotkb:Q9NSL9|uniprotkb:Q658Z3|uniprotkb:E1P539|ensembl:ENSP00000230461 psi-mi:at8b2_human(display_long)|uniprotkb:ATP8B2(gene name)|psi-mi:ATP8B2(display_short)|uniprotkb:ATPID(gene name synonym)|uniprotkb:KIAA1137(gene name synonym)|uniprotkb:ATPase class I type 8B member 2(gene name synonym)|uniprotkb:P4-ATPase flippase complex alpha subunit ATP8B2(gene name synonym) psi-mi:cc50a_human(display_long)|uniprotkb:TMEM30A(gene name)|psi-mi:TMEM30A(display_short)|uniprotkb:C6orf67(gene name synonym)|uniprotkb:CDC50A(gene name synonym)|uniprotkb:Transmembrane protein 30A(gene name synonym)|uniprotkb:P4-ATPase flippase complex beta subunit TMEM30A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) van et al. (2010) imex:IM-22613|pubmed:20947505 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9527233|imex:IM-22613-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR023214|interpro:IPR030347|reactome:R-HSA-936837|interpro:IPR032630|interpro:IPR032631|interpro:IPR044492|interpro:IPR023299|interpro:IPR018303|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|refseq:NP_001005855.1|refseq:NP_065185.1|refseq:XP_005245412.1|interpro:IPR023298|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007030"(Golgi organization)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140345"(phosphatidylcholine flippase activity)|interpro:IPR036412 refseq:NP_001137430.1|refseq:NP_060717.1|ensembl:ENSG00000112697(gene)|ensembl:ENST00000230461(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006855"(xenobiotic transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015247"(aminophospholipid flippase activity)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0061092"(positive regulation of phospholipid translocation)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR005045(Protein of unknown function DUF284, transmembrane eukaryotic)|interpro:IPR030351|mint:Q9NV96|rcsb pdb:6K7G|rcsb pdb:6K7H|rcsb pdb:6K7I|rcsb pdb:6K7J|rcsb pdb:6K7K|rcsb pdb:6K7M|rcsb pdb:6K7N|rcsb pdb:6LKN|rcsb pdb:7BSP|rcsb pdb:7BSQ|rcsb pdb:7BSS|rcsb pdb:7BSU|rcsb pdb:7BSV|rcsb pdb:7BSW|reactome:R-HSA-6798695|rcsb pdb:6K7L - - - figure legend:1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2014/05/19 2014/10/16 rogid:0qfmiw+yRBCQbBg9vx2Wzsmy53Y9606 rogid:HTSM+3ihZsx2qIRiNhutEb/Kyu09606 intact-crc:CA0D319A31A41953|rigid:SjmygEkeYryN4j6DniVzbCkHwuk false ha tag:c-c v5 tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O43520 uniprotkb:Q9NV96 intact:EBI-9524729|uniprotkb:Q9BTP8|intact:EBI-28976955|ensembl:ENSP00000497896 intact:EBI-2836942|uniprotkb:A8K9V8|uniprotkb:Q96H09|uniprotkb:Q9NSL9|uniprotkb:Q658Z3|uniprotkb:E1P539|ensembl:ENSP00000230461 psi-mi:at8b1_human(display_long)|uniprotkb:P4-ATPase flippase complex alpha subunit ATP8B1(gene name synonym)|uniprotkb:ATP8B1(gene name)|psi-mi:ATP8B1(display_short)|uniprotkb:ATPIC(gene name synonym)|uniprotkb:FIC1(gene name synonym)|uniprotkb:PFIC(gene name synonym)|uniprotkb:ATPase class I type 8B member 1(gene name synonym)|uniprotkb:Familial intrahepatic cholestasis type 1(gene name synonym) psi-mi:cc50a_human(display_long)|uniprotkb:TMEM30A(gene name)|psi-mi:TMEM30A(display_short)|uniprotkb:C6orf67(gene name synonym)|uniprotkb:CDC50A(gene name synonym)|uniprotkb:Transmembrane protein 30A(gene name synonym)|uniprotkb:P4-ATPase flippase complex beta subunit TMEM30A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) van et al. (2010) imex:IM-22613|pubmed:20947505 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9527094|imex:IM-22613-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000497896|refseq:XP_011524324.1|refseq:XP_006722544.1|refseq:NP_005594.1|ensembl:ENSG00000081923(gene)|ensembl:ENST00000648908(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006855"(xenobiotic transmembrane transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008206"(bile acid metabolic process)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0031526"(brush border membrane)|go:"GO:0032420"(stereocilium)|go:"GO:0032534"(regulation of microvillus assembly)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0045176"(apical protein localization)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0060119"(inner ear receptor cell development)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140345"(phosphatidylcholine flippase activity)|go:"GO:0140346"(phosphatidylserine flippase activity)|go:"GO:1901612"(cardiolipin binding)|go:"GO:1903729"(regulation of plasma membrane organization)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|go:"GO:2001225"(regulation of chloride transport)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023298|interpro:IPR023299|interpro:IPR030346|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|reactome:R-HSA-936837 refseq:NP_001137430.1|refseq:NP_060717.1|ensembl:ENSG00000112697(gene)|ensembl:ENST00000230461(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006855"(xenobiotic transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015247"(aminophospholipid flippase activity)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0061092"(positive regulation of phospholipid translocation)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR005045(Protein of unknown function DUF284, transmembrane eukaryotic)|interpro:IPR030351|mint:Q9NV96|rcsb pdb:6K7G|rcsb pdb:6K7H|rcsb pdb:6K7I|rcsb pdb:6K7J|rcsb pdb:6K7K|rcsb pdb:6K7M|rcsb pdb:6K7N|rcsb pdb:6LKN|rcsb pdb:7BSP|rcsb pdb:7BSQ|rcsb pdb:7BSS|rcsb pdb:7BSU|rcsb pdb:7BSV|rcsb pdb:7BSW|reactome:R-HSA-6798695|rcsb pdb:6K7L - - - figure legend:1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2014/05/19 2014/10/16 rogid:etMCmFj6oGhBGan/RrxU5eUdWCM9606 rogid:HTSM+3ihZsx2qIRiNhutEb/Kyu09606 intact-crc:EE66233E1A387CFE|rigid:2yvSqj7gC2sM/lIgVP3rtz0JSjg false ha tag:c-c v5 tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q3MIR4 uniprotkb:O43520 intact:EBI-9527107|uniprotkb:B3KR84|uniprotkb:Q14D00|ensembl:ENSP00000450842 intact:EBI-9524729|uniprotkb:Q9BTP8|intact:EBI-28976955|ensembl:ENSP00000497896 psi-mi:cc50b_human(display_long)|uniprotkb:P4-ATPase flippase complex beta subunit TMEM30B(gene name synonym)|uniprotkb:TMEM30B(gene name)|psi-mi:TMEM30B(display_short)|uniprotkb:CDC50B(gene name synonym)|uniprotkb:Transmembrane protein 30B(gene name synonym) psi-mi:at8b1_human(display_long)|uniprotkb:P4-ATPase flippase complex alpha subunit ATP8B1(gene name synonym)|uniprotkb:ATP8B1(gene name)|psi-mi:ATP8B1(display_short)|uniprotkb:ATPIC(gene name synonym)|uniprotkb:FIC1(gene name synonym)|uniprotkb:PFIC(gene name synonym)|uniprotkb:ATPase class I type 8B member 1(gene name synonym)|uniprotkb:Familial intrahepatic cholestasis type 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) van et al. (2010) imex:IM-22613|pubmed:20947505 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9527102|imex:IM-22613-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001017970.1|ensembl:ENSG00000182107(gene)|ensembl:ENST00000555868(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0015247"(aminophospholipid flippase activity)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|interpro:IPR005045(Protein of unknown function DUF284, transmembrane eukaryotic)|interpro:IPR030352 ensembl:ENSP00000497896|refseq:XP_011524324.1|refseq:XP_006722544.1|refseq:NP_005594.1|ensembl:ENSG00000081923(gene)|ensembl:ENST00000648908(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006855"(xenobiotic transmembrane transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008206"(bile acid metabolic process)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0031526"(brush border membrane)|go:"GO:0032420"(stereocilium)|go:"GO:0032534"(regulation of microvillus assembly)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0045176"(apical protein localization)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0060119"(inner ear receptor cell development)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140345"(phosphatidylcholine flippase activity)|go:"GO:0140346"(phosphatidylserine flippase activity)|go:"GO:1901612"(cardiolipin binding)|go:"GO:1903729"(regulation of plasma membrane organization)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|go:"GO:2001225"(regulation of chloride transport)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023298|interpro:IPR023299|interpro:IPR030346|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|reactome:R-HSA-936837 - - - figure legend:1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2014/05/19 2014/10/16 rogid:SEW0dE9gp2d2piEq/37EFUxcNOI9606 rogid:etMCmFj6oGhBGan/RrxU5eUdWCM9606 intact-crc:FC88A155A994EF32|rigid:GTGeuI97aNQ1cwMsV2WSwS8/TiU false v5 tag:?-? ha tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8TF62 uniprotkb:Q9NV96 intact:EBI-9527207|uniprotkb:Q9H727|ensembl:ENSP00000284509|ensembl:ENSP00000453169 intact:EBI-2836942|uniprotkb:A8K9V8|uniprotkb:Q96H09|uniprotkb:Q9NSL9|uniprotkb:Q658Z3|uniprotkb:E1P539|ensembl:ENSP00000230461 psi-mi:at8b4_human(display_long)|uniprotkb:P4-ATPase flippase complex alpha subunit ATP8B4(gene name synonym)|uniprotkb:ATP8B4(gene name)|psi-mi:ATP8B4(display_short)|uniprotkb:KIAA1939(gene name synonym)|uniprotkb:ATPase class I type 8B member 4(gene name synonym) psi-mi:cc50a_human(display_long)|uniprotkb:TMEM30A(gene name)|psi-mi:TMEM30A(display_short)|uniprotkb:C6orf67(gene name synonym)|uniprotkb:CDC50A(gene name synonym)|uniprotkb:Transmembrane protein 30A(gene name synonym)|uniprotkb:P4-ATPase flippase complex beta subunit TMEM30A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) van et al. (2010) imex:IM-22613|pubmed:20947505 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9527124|imex:IM-22613-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016878081.1|refseq:NP_079113.2|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023298|interpro:IPR023299|interpro:IPR030348|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|reactome:R-HSA-6798695|reactome:R-HSA-936837|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|ensembl:ENSG00000104043(gene)|ensembl:ENST00000284509(transcript)|ensembl:ENST00000559829(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity) refseq:NP_001137430.1|refseq:NP_060717.1|ensembl:ENSG00000112697(gene)|ensembl:ENST00000230461(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006855"(xenobiotic transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015247"(aminophospholipid flippase activity)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0061092"(positive regulation of phospholipid translocation)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR005045(Protein of unknown function DUF284, transmembrane eukaryotic)|interpro:IPR030351|mint:Q9NV96|rcsb pdb:6K7G|rcsb pdb:6K7H|rcsb pdb:6K7I|rcsb pdb:6K7J|rcsb pdb:6K7K|rcsb pdb:6K7M|rcsb pdb:6K7N|rcsb pdb:6LKN|rcsb pdb:7BSP|rcsb pdb:7BSQ|rcsb pdb:7BSS|rcsb pdb:7BSU|rcsb pdb:7BSV|rcsb pdb:7BSW|reactome:R-HSA-6798695|rcsb pdb:6K7L - - - figure legend:1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2014/05/19 2014/10/16 rogid:p2oNvE1dnA+/mAD6cF/FREbZjAk9606 rogid:HTSM+3ihZsx2qIRiNhutEb/Kyu09606 intact-crc:93611B8D5151C63A|rigid:GNt0RJ8ppR6QZz5FO9bEClHGYzE false ha tag:c-c v5 tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8TF62 uniprotkb:Q3MIR4 intact:EBI-9527207|uniprotkb:Q9H727|ensembl:ENSP00000284509|ensembl:ENSP00000453169 intact:EBI-9527107|uniprotkb:B3KR84|uniprotkb:Q14D00|ensembl:ENSP00000450842 psi-mi:at8b4_human(display_long)|uniprotkb:P4-ATPase flippase complex alpha subunit ATP8B4(gene name synonym)|uniprotkb:ATP8B4(gene name)|psi-mi:ATP8B4(display_short)|uniprotkb:KIAA1939(gene name synonym)|uniprotkb:ATPase class I type 8B member 4(gene name synonym) psi-mi:cc50b_human(display_long)|uniprotkb:P4-ATPase flippase complex beta subunit TMEM30B(gene name synonym)|uniprotkb:TMEM30B(gene name)|psi-mi:TMEM30B(display_short)|uniprotkb:CDC50B(gene name synonym)|uniprotkb:Transmembrane protein 30B(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) van et al. (2010) imex:IM-22613|pubmed:20947505 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-9542170|imex:IM-22613-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016878081.1|refseq:NP_079113.2|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023298|interpro:IPR023299|interpro:IPR030348|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|reactome:R-HSA-6798695|reactome:R-HSA-936837|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|ensembl:ENSG00000104043(gene)|ensembl:ENST00000284509(transcript)|ensembl:ENST00000559829(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity) refseq:NP_001017970.1|ensembl:ENSG00000182107(gene)|ensembl:ENST00000555868(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0015247"(aminophospholipid flippase activity)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|interpro:IPR005045(Protein of unknown function DUF284, transmembrane eukaryotic)|interpro:IPR030352 go:"GO:0005886"(plasma membrane) - - figure legend:2D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2014/05/19 2014/10/16 rogid:p2oNvE1dnA+/mAD6cF/FREbZjAk9606 rogid:SEW0dE9gp2d2piEq/37EFUxcNOI9606 intact-crc:6BFD359EF4CD48F1|rigid:iLZwxLaeu8TSbmOi/6FCtJsZOfU false ha tag:c-c v5 tag:c-c - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0707"(anti tag immunostaining) uniprotkb:Q9NV96 uniprotkb:P98198 intact:EBI-2836942|uniprotkb:A8K9V8|uniprotkb:Q96H09|uniprotkb:Q9NSL9|uniprotkb:Q658Z3|uniprotkb:E1P539|ensembl:ENSP00000230461 intact:EBI-9539266|uniprotkb:B4E3P4|uniprotkb:Q6NT69|uniprotkb:Q7Z486|uniprotkb:Q96I43|uniprotkb:Q96NQ7 psi-mi:cc50a_human(display_long)|uniprotkb:TMEM30A(gene name)|psi-mi:TMEM30A(display_short)|uniprotkb:C6orf67(gene name synonym)|uniprotkb:CDC50A(gene name synonym)|uniprotkb:Transmembrane protein 30A(gene name synonym)|uniprotkb:P4-ATPase flippase complex beta subunit TMEM30A(gene name synonym) psi-mi:at8b2_human(display_long)|uniprotkb:ATP8B2(gene name)|psi-mi:ATP8B2(display_short)|uniprotkb:ATPID(gene name synonym)|uniprotkb:KIAA1137(gene name synonym)|uniprotkb:ATPase class I type 8B member 2(gene name synonym)|uniprotkb:P4-ATPase flippase complex alpha subunit ATP8B2(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) van et al. (2010) imex:IM-22613|pubmed:20947505 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-9539416|imex:IM-22613-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001137430.1|refseq:NP_060717.1|ensembl:ENSG00000112697(gene)|ensembl:ENST00000230461(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006855"(xenobiotic transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015247"(aminophospholipid flippase activity)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0061092"(positive regulation of phospholipid translocation)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR005045(Protein of unknown function DUF284, transmembrane eukaryotic)|interpro:IPR030351|mint:Q9NV96|rcsb pdb:6K7G|rcsb pdb:6K7H|rcsb pdb:6K7I|rcsb pdb:6K7J|rcsb pdb:6K7K|rcsb pdb:6K7M|rcsb pdb:6K7N|rcsb pdb:6LKN|rcsb pdb:7BSP|rcsb pdb:7BSQ|rcsb pdb:7BSS|rcsb pdb:7BSU|rcsb pdb:7BSV|rcsb pdb:7BSW|reactome:R-HSA-6798695|rcsb pdb:6K7L interpro:IPR023214|interpro:IPR030347|reactome:R-HSA-936837|interpro:IPR032630|interpro:IPR032631|interpro:IPR044492|interpro:IPR023299|interpro:IPR018303|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|refseq:NP_001005855.1|refseq:NP_065185.1|refseq:XP_005245412.1|interpro:IPR023298|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007030"(Golgi organization)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140345"(phosphatidylcholine flippase activity)|interpro:IPR036412 go:"GO:0005886"(plasma membrane) - - figure legend:2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2014/05/19 2014/10/16 rogid:HTSM+3ihZsx2qIRiNhutEb/Kyu09606 rogid:0qfmiw+yRBCQbBg9vx2Wzsmy53Y9606 intact-crc:850CB8A481FF372B|rigid:SjmygEkeYryN4j6DniVzbCkHwuk false v5 tag:c-c ha tag:c-c - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0707"(anti tag immunostaining) uniprotkb:Q8TF62 uniprotkb:Q9NV96 intact:EBI-9527207|uniprotkb:Q9H727|ensembl:ENSP00000284509|ensembl:ENSP00000453169 intact:EBI-2836942|uniprotkb:A8K9V8|uniprotkb:Q96H09|uniprotkb:Q9NSL9|uniprotkb:Q658Z3|uniprotkb:E1P539|ensembl:ENSP00000230461 psi-mi:at8b4_human(display_long)|uniprotkb:P4-ATPase flippase complex alpha subunit ATP8B4(gene name synonym)|uniprotkb:ATP8B4(gene name)|psi-mi:ATP8B4(display_short)|uniprotkb:KIAA1939(gene name synonym)|uniprotkb:ATPase class I type 8B member 4(gene name synonym) psi-mi:cc50a_human(display_long)|uniprotkb:TMEM30A(gene name)|psi-mi:TMEM30A(display_short)|uniprotkb:C6orf67(gene name synonym)|uniprotkb:CDC50A(gene name synonym)|uniprotkb:Transmembrane protein 30A(gene name synonym)|uniprotkb:P4-ATPase flippase complex beta subunit TMEM30A(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) van et al. (2010) imex:IM-22613|pubmed:20947505 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-9539426|imex:IM-22613-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016878081.1|refseq:NP_079113.2|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023298|interpro:IPR023299|interpro:IPR030348|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|reactome:R-HSA-6798695|reactome:R-HSA-936837|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|ensembl:ENSG00000104043(gene)|ensembl:ENST00000284509(transcript)|ensembl:ENST00000559829(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity) refseq:NP_001137430.1|refseq:NP_060717.1|ensembl:ENSG00000112697(gene)|ensembl:ENST00000230461(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006855"(xenobiotic transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015247"(aminophospholipid flippase activity)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0061092"(positive regulation of phospholipid translocation)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR005045(Protein of unknown function DUF284, transmembrane eukaryotic)|interpro:IPR030351|mint:Q9NV96|rcsb pdb:6K7G|rcsb pdb:6K7H|rcsb pdb:6K7I|rcsb pdb:6K7J|rcsb pdb:6K7K|rcsb pdb:6K7M|rcsb pdb:6K7N|rcsb pdb:6LKN|rcsb pdb:7BSP|rcsb pdb:7BSQ|rcsb pdb:7BSS|rcsb pdb:7BSU|rcsb pdb:7BSV|rcsb pdb:7BSW|reactome:R-HSA-6798695|rcsb pdb:6K7L go:"GO:0005886"(plasma membrane) - - figure legend:2D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2014/05/19 2014/10/16 rogid:p2oNvE1dnA+/mAD6cF/FREbZjAk9606 rogid:HTSM+3ihZsx2qIRiNhutEb/Kyu09606 intact-crc:6C0A43445120F2FB|rigid:GNt0RJ8ppR6QZz5FO9bEClHGYzE false ha tag:c-c v5 tag:c-c - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0707"(anti tag immunostaining) uniprotkb:Q9NV96 uniprotkb:Q9Y2Q0 intact:EBI-2836942|uniprotkb:A8K9V8|uniprotkb:Q96H09|uniprotkb:Q9NSL9|uniprotkb:Q658Z3|uniprotkb:E1P539|ensembl:ENSP00000230461 intact:EBI-9539324|uniprotkb:Q32M35|uniprotkb:Q32M36|uniprotkb:Q4W5J7|uniprotkb:Q4W5P2|ensembl:ENSP00000371084 psi-mi:cc50a_human(display_long)|uniprotkb:TMEM30A(gene name)|psi-mi:TMEM30A(display_short)|uniprotkb:C6orf67(gene name synonym)|uniprotkb:CDC50A(gene name synonym)|uniprotkb:Transmembrane protein 30A(gene name synonym)|uniprotkb:P4-ATPase flippase complex beta subunit TMEM30A(gene name synonym) psi-mi:at8a1_human(display_long)|uniprotkb:ATP8A1(gene name)|psi-mi:ATP8A1(display_short)|uniprotkb:ATPIA(gene name synonym)|uniprotkb:ATPase class I type 8A member 1(gene name synonym)|uniprotkb:Chromaffin granule ATPase II(gene name synonym)|uniprotkb:P4-ATPase flippase complex alpha subunit ATP8A1(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) van et al. (2010) imex:IM-22613|pubmed:20947505 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-9539422|imex:IM-22613-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001137430.1|refseq:NP_060717.1|ensembl:ENSG00000112697(gene)|ensembl:ENST00000230461(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006855"(xenobiotic transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015247"(aminophospholipid flippase activity)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0061092"(positive regulation of phospholipid translocation)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR005045(Protein of unknown function DUF284, transmembrane eukaryotic)|interpro:IPR030351|mint:Q9NV96|rcsb pdb:6K7G|rcsb pdb:6K7H|rcsb pdb:6K7I|rcsb pdb:6K7J|rcsb pdb:6K7K|rcsb pdb:6K7M|rcsb pdb:6K7N|rcsb pdb:6LKN|rcsb pdb:7BSP|rcsb pdb:7BSQ|rcsb pdb:7BSS|rcsb pdb:7BSU|rcsb pdb:7BSV|rcsb pdb:7BSW|reactome:R-HSA-6798695|rcsb pdb:6K7L refseq:NP_001098999.1|refseq:NP_006086.1|refseq:XP_016863134.1|ensembl:ENSG00000124406(gene)|ensembl:ENST00000381668(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0007612"(learning)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031090"(organelle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042584"(chromaffin granule membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0061092"(positive regulation of phospholipid translocation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140331"(aminophospholipid translocation)|go:"GO:0140346"(phosphatidylserine flippase activity)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:6K7G|rcsb pdb:6K7H|rcsb pdb:6K7I|rcsb pdb:6K7J|rcsb pdb:6K7K|rcsb pdb:6K7L|rcsb pdb:6K7M|rcsb pdb:6K7N|reactome:R-HSA-6798695|reactome:R-HSA-936837|go:"GO:0005783"(endoplasmic reticulum) go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane) - - figure legend:2E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2014/05/19 2014/10/16 rogid:HTSM+3ihZsx2qIRiNhutEb/Kyu09606 rogid:dgEEryBicD80N5Kh567D+KQDV5g9606 intact-crc:8E92FCF191D6264D|rigid:zMEkJn/3TvvyLf2+SHBevulmzXg false v5 tag:c-c ha tag:c-c - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0707"(anti tag immunostaining) uniprotkb:O43520 uniprotkb:Q3MIR4 intact:EBI-9524729|uniprotkb:Q9BTP8|intact:EBI-28976955|ensembl:ENSP00000497896 intact:EBI-9527107|uniprotkb:B3KR84|uniprotkb:Q14D00|ensembl:ENSP00000450842 psi-mi:at8b1_human(display_long)|uniprotkb:P4-ATPase flippase complex alpha subunit ATP8B1(gene name synonym)|uniprotkb:ATP8B1(gene name)|psi-mi:ATP8B1(display_short)|uniprotkb:ATPIC(gene name synonym)|uniprotkb:FIC1(gene name synonym)|uniprotkb:PFIC(gene name synonym)|uniprotkb:ATPase class I type 8B member 1(gene name synonym)|uniprotkb:Familial intrahepatic cholestasis type 1(gene name synonym) psi-mi:cc50b_human(display_long)|uniprotkb:P4-ATPase flippase complex beta subunit TMEM30B(gene name synonym)|uniprotkb:TMEM30B(gene name)|psi-mi:TMEM30B(display_short)|uniprotkb:CDC50B(gene name synonym)|uniprotkb:Transmembrane protein 30B(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) van et al. (2010) imex:IM-22613|pubmed:20947505 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-9539420|imex:IM-22613-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000497896|refseq:XP_011524324.1|refseq:XP_006722544.1|refseq:NP_005594.1|ensembl:ENSG00000081923(gene)|ensembl:ENST00000648908(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006855"(xenobiotic transmembrane transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008206"(bile acid metabolic process)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0031526"(brush border membrane)|go:"GO:0032420"(stereocilium)|go:"GO:0032534"(regulation of microvillus assembly)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0045176"(apical protein localization)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0060119"(inner ear receptor cell development)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140345"(phosphatidylcholine flippase activity)|go:"GO:0140346"(phosphatidylserine flippase activity)|go:"GO:1901612"(cardiolipin binding)|go:"GO:1903729"(regulation of plasma membrane organization)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|go:"GO:2001225"(regulation of chloride transport)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023298|interpro:IPR023299|interpro:IPR030346|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|reactome:R-HSA-936837 refseq:NP_001017970.1|ensembl:ENSG00000182107(gene)|ensembl:ENST00000555868(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0015247"(aminophospholipid flippase activity)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|interpro:IPR005045(Protein of unknown function DUF284, transmembrane eukaryotic)|interpro:IPR030352 go:"GO:0005886"(plasma membrane) - - figure legend:2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2014/05/19 2014/10/16 rogid:etMCmFj6oGhBGan/RrxU5eUdWCM9606 rogid:SEW0dE9gp2d2piEq/37EFUxcNOI9606 intact-crc:CBE47D6381EEDFE5|rigid:GTGeuI97aNQ1cwMsV2WSwS8/TiU false ha tag:c-c v5 tag:?-? - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0707"(anti tag immunostaining) uniprotkb:Q9NV96 uniprotkb:O43520 intact:EBI-2836942|uniprotkb:A8K9V8|uniprotkb:Q96H09|uniprotkb:Q9NSL9|uniprotkb:Q658Z3|uniprotkb:E1P539|ensembl:ENSP00000230461 intact:EBI-9524729|uniprotkb:Q9BTP8|intact:EBI-28976955|ensembl:ENSP00000497896 psi-mi:cc50a_human(display_long)|uniprotkb:TMEM30A(gene name)|psi-mi:TMEM30A(display_short)|uniprotkb:C6orf67(gene name synonym)|uniprotkb:CDC50A(gene name synonym)|uniprotkb:Transmembrane protein 30A(gene name synonym)|uniprotkb:P4-ATPase flippase complex beta subunit TMEM30A(gene name synonym) psi-mi:at8b1_human(display_long)|uniprotkb:P4-ATPase flippase complex alpha subunit ATP8B1(gene name synonym)|uniprotkb:ATP8B1(gene name)|psi-mi:ATP8B1(display_short)|uniprotkb:ATPIC(gene name synonym)|uniprotkb:FIC1(gene name synonym)|uniprotkb:PFIC(gene name synonym)|uniprotkb:ATPase class I type 8B member 1(gene name synonym)|uniprotkb:Familial intrahepatic cholestasis type 1(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) van et al. (2010) imex:IM-22613|pubmed:20947505 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-9539424|imex:IM-22613-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001137430.1|refseq:NP_060717.1|ensembl:ENSG00000112697(gene)|ensembl:ENST00000230461(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006855"(xenobiotic transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015247"(aminophospholipid flippase activity)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0061092"(positive regulation of phospholipid translocation)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR005045(Protein of unknown function DUF284, transmembrane eukaryotic)|interpro:IPR030351|mint:Q9NV96|rcsb pdb:6K7G|rcsb pdb:6K7H|rcsb pdb:6K7I|rcsb pdb:6K7J|rcsb pdb:6K7K|rcsb pdb:6K7M|rcsb pdb:6K7N|rcsb pdb:6LKN|rcsb pdb:7BSP|rcsb pdb:7BSQ|rcsb pdb:7BSS|rcsb pdb:7BSU|rcsb pdb:7BSV|rcsb pdb:7BSW|reactome:R-HSA-6798695|rcsb pdb:6K7L ensembl:ENSP00000497896|refseq:XP_011524324.1|refseq:XP_006722544.1|refseq:NP_005594.1|ensembl:ENSG00000081923(gene)|ensembl:ENST00000648908(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006855"(xenobiotic transmembrane transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008206"(bile acid metabolic process)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0031526"(brush border membrane)|go:"GO:0032420"(stereocilium)|go:"GO:0032534"(regulation of microvillus assembly)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0045176"(apical protein localization)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0060119"(inner ear receptor cell development)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140345"(phosphatidylcholine flippase activity)|go:"GO:0140346"(phosphatidylserine flippase activity)|go:"GO:1901612"(cardiolipin binding)|go:"GO:1903729"(regulation of plasma membrane organization)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|go:"GO:2001225"(regulation of chloride transport)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023298|interpro:IPR023299|interpro:IPR030346|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|reactome:R-HSA-936837 go:"GO:0005886"(plasma membrane) - - figure legend:2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2014/05/19 2014/10/16 rogid:HTSM+3ihZsx2qIRiNhutEb/Kyu09606 rogid:etMCmFj6oGhBGan/RrxU5eUdWCM9606 intact-crc:F8EA83E95E2F7FF4|rigid:2yvSqj7gC2sM/lIgVP3rtz0JSjg false v5 tag:c-c ha tag:c-c - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0707"(anti tag immunostaining) uniprotkb:Q9NV96 uniprotkb:Q9NTI2 intact:EBI-2836942|uniprotkb:A8K9V8|uniprotkb:Q96H09|uniprotkb:Q9NSL9|uniprotkb:Q658Z3|uniprotkb:E1P539|ensembl:ENSP00000230461 intact:EBI-9539366|uniprotkb:Q9H527|uniprotkb:Q9NPU6|uniprotkb:Q9NTL2|uniprotkb:Q9NYM3|uniprotkb:Q6ZSP3|ensembl:ENSP00000371070 psi-mi:cc50a_human(display_long)|uniprotkb:TMEM30A(gene name)|psi-mi:TMEM30A(display_short)|uniprotkb:C6orf67(gene name synonym)|uniprotkb:CDC50A(gene name synonym)|uniprotkb:Transmembrane protein 30A(gene name synonym)|uniprotkb:P4-ATPase flippase complex beta subunit TMEM30A(gene name synonym) psi-mi:at8a2_human(display_long)|uniprotkb:ATP8A2(gene name)|psi-mi:ATP8A2(display_short)|uniprotkb:ATPIB(gene name synonym)|uniprotkb:ATPase class I type 8A member 2(gene name synonym)|uniprotkb:ML-1(gene name synonym)|uniprotkb:P4-ATPase flippase complex alpha subunit ATP8A2(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) van et al. (2010) imex:IM-22613|pubmed:20947505 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-9539414|imex:IM-22613-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001137430.1|refseq:NP_060717.1|ensembl:ENSG00000112697(gene)|ensembl:ENST00000230461(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006855"(xenobiotic transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015247"(aminophospholipid flippase activity)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0061092"(positive regulation of phospholipid translocation)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR005045(Protein of unknown function DUF284, transmembrane eukaryotic)|interpro:IPR030351|mint:Q9NV96|rcsb pdb:6K7G|rcsb pdb:6K7H|rcsb pdb:6K7I|rcsb pdb:6K7J|rcsb pdb:6K7K|rcsb pdb:6K7M|rcsb pdb:6K7N|rcsb pdb:6LKN|rcsb pdb:7BSP|rcsb pdb:7BSQ|rcsb pdb:7BSS|rcsb pdb:7BSU|rcsb pdb:7BSV|rcsb pdb:7BSW|reactome:R-HSA-6798695|rcsb pdb:6K7L refseq:XP_005266476.1|refseq:NP_001300670.1|refseq:NP_057613.4|ensembl:ENSG00000132932(gene)|ensembl:ENST00000381655(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003011"(involuntary skeletal muscle contraction)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007409"(axonogenesis)|go:"GO:0007568"(aging)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010842"(retina layer formation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010996"(response to auditory stimulus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042755"(eating behavior)|go:"GO:0043588"(skin development)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0048666"(neuron development)|go:"GO:0050884"(neuromuscular process controlling posture)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0061092"(positive regulation of phospholipid translocation)|go:"GO:0090555"(phosphatidylethanolamine flippase activity)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140331"(aminophospholipid translocation)|go:"GO:0140346"(phosphatidylserine flippase activity)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|reactome:R-HSA-936837 go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane) - - figure legend:2F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2014/05/19 2018/09/18 rogid:HTSM+3ihZsx2qIRiNhutEb/Kyu09606 rogid:8yFwrBfiZ3VYycp5AjHKdx9HKgg9606 intact-crc:69D676BB99D15F37|rigid:x40ib0/UzyY8tmyYIk4ejo6kpHA false v5 tag:c-c tag:c-c - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0707"(anti tag immunostaining)