#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9QZ88	uniprotkb:A8K0Z3	intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020	intact:EBI-6160405|intact:EBI-28977476|ensembl:ENSP00000485627	psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym)	psi-mi:wash1_human(display_long)|uniprotkb:WASHC1(gene name)|psi-mi:WASHC1(display_short)|uniprotkb:CXYorf1-like protein on chromosome 9(gene name synonym)|uniprotkb:FAM39E(gene name synonym)|uniprotkb:Protein FAM39E(gene name synonym)|uniprotkb:WAS protein family homolog 1(gene name synonym)|uniprotkb:WASH1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9845847|imex:IM-26126-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome)	ensembl:ENSP00000485627|refseq:NP_878908.4|ensembl:ENSG00000181404(gene)|ensembl:ENST00000442898(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031274"(positive regulation of pseudopodium assembly)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043553"(negative regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071203"(WASH complex)|interpro:IPR021854|interpro:IPR028290	-	function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint	-	figure legend:1A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2018/09/18	rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090	rogid:X7zdUL7YK2B6tU4RUdSTXrJfXLk9606	intact-crc:B8BBF4BD1537B263|rigid:2DsnRYJESuqNE0JvcM2WPVxDN24	false	mutation disrupting interaction strength:91-91|green fluorescent protein tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9QZ88	uniprotkb:Q4G0F5	intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020	intact:EBI-6151831|uniprotkb:Q96A55|ensembl:ENSP00000281187|ensembl:ENSP00000434162	psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym)	psi-mi:vp26b_human(display_long)|uniprotkb:Vesicle protein sorting 26B(gene name synonym)|uniprotkb:VPS26B(gene name)|psi-mi:VPS26B(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9845847|imex:IM-26126-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome)	refseq:NP_443107.1|ensembl:ENSG00000151502(gene)|ensembl:ENST00000281187(transcript)|ensembl:ENST00000525095(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR028934	-	function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint	-	figure legend:1A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2018/09/18	rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090	rogid:8NQBMiFKQXjWM4/Vy7swv2pW0V89606	intact-crc:B8BBF4BD1537B263|rigid:2DsnRYJESuqNE0JvcM2WPVxDN24	false	mutation disrupting interaction strength:91-91|green fluorescent protein tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9QZ88	uniprotkb:Q5T1M5	intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020	intact:EBI-5235934|uniprotkb:Q05DK8|uniprotkb:Q5T1M2|uniprotkb:Q6DD85|uniprotkb:Q9Y4D0|ensembl:ENSP00000238256|ensembl:ENSP00000416158	psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym)	psi-mi:fkb15_human(display_long)|uniprotkb:FKBP15(gene name)|psi-mi:FKBP15(display_short)|uniprotkb:KIAA0674(gene name synonym)|uniprotkb:133 kDa FK506-binding protein(gene name synonym)|uniprotkb:WASP- and FKBP-like protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9845847|imex:IM-26126-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome)	refseq:NP_056073.1|refseq:XP_006717081.1|ensembl:ENSG00000119321(gene)|ensembl:ENST00000238256(transcript)|ensembl:ENST00000446284(transcript)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0003779"(actin binding)|go:"GO:0005769"(early endosome)|go:"GO:0006897"(endocytosis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030426"(growth cone)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|mint:Q5T1M5	-	function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint	-	figure legend:1A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2018/09/18	rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090	rogid:2th35ZHTzidVTyWGpc0Emz3foIY9606	intact-crc:B8BBF4BD1537B263|rigid:2DsnRYJESuqNE0JvcM2WPVxDN24	false	mutation disrupting interaction strength:91-91|green fluorescent protein tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9QZ88	uniprotkb:Q2M389	intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020	intact:EBI-2563783|uniprotkb:Q8IW61|uniprotkb:Q9NVD6|uniprotkb:Q8N5W7|uniprotkb:Q2NL83|uniprotkb:Q9UPW7|ensembl:ENSP00000328062	psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym)	psi-mi:wasc4_human(display_long)|uniprotkb:WASHC4(gene name)|psi-mi:WASHC4(display_short)|uniprotkb:KIAA1033(gene name synonym)|uniprotkb:Strumpellin and WASH-interacting protein(gene name synonym)|uniprotkb:WASH complex subunit SWIP(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9845847|imex:IM-26126-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome)	refseq:NP_056090.1|ensembl:ENSG00000136051(gene)|ensembl:ENST00000332180(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0007032"(endosome organization)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0071203"(WASH complex)|go:"GO:0140591"(nuclear envelope budding)|interpro:IPR027307|interpro:IPR028191|interpro:IPR028283|interpro:IPR028282|refseq:NP_001280569.1	-	function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint	-	figure legend:1A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2018/09/18	rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090	rogid:APnP9mxAqwzKEoQFGt94Z8Y73t49606	intact-crc:B8BBF4BD1537B263|rigid:2DsnRYJESuqNE0JvcM2WPVxDN24	false	mutation disrupting interaction strength:91-91|green fluorescent protein tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9QZ88	uniprotkb:Q96QK1	intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020	intact:EBI-1054634|uniprotkb:Q561W2|uniprotkb:Q9H016|uniprotkb:Q9H096|uniprotkb:Q9H4P3|uniprotkb:Q9H8J0|uniprotkb:Q9NRS7|uniprotkb:Q9NVG2|uniprotkb:Q9NX80|uniprotkb:Q9NZK2|ensembl:ENSP00000299138	psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym)	psi-mi:vps35_human(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:VPS35(gene name)|psi-mi:VPS35(display_short)|uniprotkb:MEM3(gene name synonym)|uniprotkb:TCCCTA00141(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9845847|imex:IM-26126-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome)	refseq:NP_060676.2|rcsb pdb:5F0J|rcsb pdb:5F0K|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|rcsb pdb:5OSH|rcsb pdb:5OSI|rcsb pdb:7BLN|rcsb pdb:7BLO|reactome:R-HSA-3238698|ensembl:ENSG00000069329(gene)|ensembl:ENST00000299138(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0097422"(tubular endosome)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|rcsb pdb:2R17|dip:DIP-29076N	-	function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint	-	figure legend:1A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2018/09/18	rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090	rogid:EXkMduDQKNCdp876vGF5vna9t389606	intact-crc:B8BBF4BD1537B263|rigid:2DsnRYJESuqNE0JvcM2WPVxDN24	false	mutation disrupting interaction strength:91-91|green fluorescent protein tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9QZ88	uniprotkb:Q9Y4E1	intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020	intact:EBI-948957|intact:EBI-28970026|ensembl:ENSP00000363482|uniprotkb:Q5SQU4|uniprotkb:Q5SQU5|uniprotkb:Q7L521|uniprotkb:Q9UG79|intact:EBI-2563814|uniprotkb:B4DZQ6|uniprotkb:B9EK53|uniprotkb:F5H0J6|uniprotkb:F5H871	psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym)	psi-mi:wac2c_human(display_long)|uniprotkb:VPEF(gene name synonym)|uniprotkb:WASHC2C(gene name)|psi-mi:WASHC2C(display_short)|uniprotkb:FAM21C(gene name synonym)|uniprotkb:KIAA0592(gene name synonym)|uniprotkb:Vaccinia virus penetration factor(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9845847|imex:IM-26126-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome)	ensembl:ENSG00000172661(gene)|ensembl:ENST00000374362(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0015031"(protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032456"(endocytic recycling)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0071203"(WASH complex)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1900024"(regulation of substrate adhesion-dependent cell spreading)|go:"GO:1905394"(retromer complex binding)|go:"GO:2000813"(negative regulation of barbed-end actin filament capping)|interpro:IPR029341|mint:Q9Y4E1|ensembl:ENST00000540872|ensembl:ENSP00000439811|ensembl:ENSP00000363482|ensembl:ENST00000537517|ensembl:ENSP00000442128|refseq:NP_001162577.1|refseq:NP_001162578.1|refseq:NP_056077.2	-	function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint	-	figure legend:1A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2018/09/18	rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090	rogid:gUK2aPVIQiHey/Wka1mgFuBTKNE9606	intact-crc:B8BBF4BD1537B263|rigid:2DsnRYJESuqNE0JvcM2WPVxDN24	false	mutation disrupting interaction strength:91-91|green fluorescent protein tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9QZ88	uniprotkb:Q12768	intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020	intact:EBI-2563794|uniprotkb:A8K4R7|uniprotkb:Q3KQX5|uniprotkb:Q8TBQ2|ensembl:ENSP00000318016	psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym)	psi-mi:wasc5_human(display_long)|uniprotkb:WASHC5(gene name)|psi-mi:WASHC5(display_short)|uniprotkb:KIAA0196(gene name synonym)|uniprotkb:Strumpellin(gene name synonym)|uniprotkb:WASH complex subunit strumpellin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9845847|imex:IM-26126-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome)	refseq:NP_055661.3|ensembl:ENSG00000164961(gene)|ensembl:ENST00000318410(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0034629"|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051125"(regulation of actin nucleation)|go:"GO:0071203"(WASH complex)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0097494"(regulation of vesicle size)|go:"GO:0140285"(endosome fission)|interpro:IPR019393|mint:Q12768|refseq:XP_016869602.1	-	function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint	-	figure legend:1A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2018/09/18	rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090	rogid:9QEw0Z7NIOvpVJtWXcLp67ApJdk9606	intact-crc:B8BBF4BD1537B263|rigid:2DsnRYJESuqNE0JvcM2WPVxDN24	false	mutation disrupting interaction strength:91-91|green fluorescent protein tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9QZ88	uniprotkb:Q92609	intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020	intact:EBI-742381|uniprotkb:A6NP25|intact:EBI-28978959|ensembl:ENSP00000253692|ensembl:ENSP00000398127|uniprotkb:C9JP52	psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym)	psi-mi:tbcd5_human(display_long)|uniprotkb:TBC1D5(gene name)|psi-mi:TBC1D5(display_short)|uniprotkb:KIAA0210(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9845847|imex:IM-26126-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome)	ensembl:ENSP00000253692|ensembl:ENSP00000398127|ensembl:ENSP00000402935|ensembl:ENST00000446818|refseq:NP_055559.1|refseq:XP_011532586.1|refseq:XP_011532583.1|refseq:XP_011532585.1|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006914"(autophagy)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0035612"(AP-2 adaptor complex binding)|ensembl:ENSG00000131374(gene)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042594"(response to starvation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1905394"(retromer complex binding)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|mint:Q92609|rcsb pdb:5GTU|ensembl:ENST00000253692(transcript)|ensembl:ENST00000429383(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|refseq:NP_001127853.1|refseq:XP_006713493.1|refseq:XP_016863041.1|refseq:XP_016863042.1|refseq:XP_016863043.1|refseq:XP_016863044.1|refseq:XP_016863045.1|refseq:XP_016863046.1	-	function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint	-	figure legend:1A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2018/09/18	rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090	rogid:GZ7WP4suMiSPSAJK0TZWQMQZxzU9606	intact-crc:B8BBF4BD1537B263|rigid:2DsnRYJESuqNE0JvcM2WPVxDN24	false	mutation disrupting interaction strength:91-91|green fluorescent protein tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9QZ88	uniprotkb:P52907	intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020	intact:EBI-355586|uniprotkb:Q53FQ6|uniprotkb:Q6FHD5|ensembl:ENSP00000263168	psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym)	psi-mi:caza1_human(display_long)|uniprotkb:CAPZA1(gene name)|psi-mi:CAPZA1(display_short)|uniprotkb:CapZ alpha-1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9845847|imex:IM-26126-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome)	refseq:NP_006126.1|ensembl:ENSG00000116489(gene)|ensembl:ENST00000263168(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0034329"(cell junction assembly)|go:"GO:0045296"(cadherin binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071203"(WASH complex)|interpro:IPR002189(F-actin capping protein, alpha subunit)|interpro:IPR017865|interpro:IPR037282|interpro:IPR042276|interpro:IPR042489|mint:P52907|rcsb pdb:1MQ1|rcsb pdb:1MWN|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-879415|reactome:R-HSA-8950505|reactome:R-HSA-9662360|reactome:R-HSA-983231	-	function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint	-	figure legend:1A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2018/09/18	rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090	rogid:97S4WPtjgt4MDLoptRhQ2yH8UNE9606	intact-crc:B8BBF4BD1537B263|rigid:2DsnRYJESuqNE0JvcM2WPVxDN24	false	mutation disrupting interaction strength:91-91|green fluorescent protein tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9QZ88	uniprotkb:O75436	intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020	intact:EBI-1043891|uniprotkb:Q8TBH4|uniprotkb:Q9H982|ensembl:ENSP00000263559|ensembl:ENSP00000362480|uniprotkb:B2RDD3|uniprotkb:A8MZ56	psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym)	psi-mi:vp26a_human(display_long)|uniprotkb:VPS26A(gene name)|psi-mi:VPS26A(display_short)|uniprotkb:VPS26(gene name synonym)|uniprotkb:Vesicle protein sorting 26A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9845847|imex:IM-26126-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome)	ensembl:ENSG00000122958(gene)|ensembl:ENST00000263559(transcript)|ensembl:ENST00000373382(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031982"(vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0097422"(tubular endosome)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR028934|mint:O75436|rcsb pdb:2FAU|rcsb pdb:5F0J|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|reactome:R-HSA-3238698|rcsb pdb:7BLO|refseq:NP_001030337.1|refseq:NP_004887.2|refseq:NP_001305875.1|dip:DIP-29075N	-	function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint	-	figure legend:1A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2018/09/18	rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090	rogid:n0uOd+2HQmRW7koIy678uP0d3+o9606	intact-crc:B8BBF4BD1537B263|rigid:2DsnRYJESuqNE0JvcM2WPVxDN24	false	mutation disrupting interaction strength:91-91|green fluorescent protein tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q92609	uniprotkb:Q9UBQ0	intact:EBI-742381|uniprotkb:A6NP25|intact:EBI-28978959|ensembl:ENSP00000253692|ensembl:ENSP00000398127|uniprotkb:C9JP52	intact:EBI-718596|uniprotkb:Q502Y5|uniprotkb:Q9H0W0|uniprotkb:Q9NRP1|uniprotkb:Q6FIF8|uniprotkb:Q6IAH3|uniprotkb:Q9NRU7|ensembl:ENSP00000447058	psi-mi:tbcd5_human(display_long)|uniprotkb:TBC1D5(gene name)|psi-mi:TBC1D5(display_short)|uniprotkb:KIAA0210(gene name synonym)	psi-mi:vps29_human(display_long)|uniprotkb:Vesicle protein sorting 29(gene name synonym)|uniprotkb:PEP11 homolog(gene name synonym)|uniprotkb:VPS29(gene name)|psi-mi:VPS29(display_short)|uniprotkb:DC7(orf name)|uniprotkb:DC15(orf name)|uniprotkb:MDS007(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846549|imex:IM-26126-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000253692|ensembl:ENSP00000398127|ensembl:ENSP00000402935|ensembl:ENST00000446818|refseq:NP_055559.1|refseq:XP_011532586.1|refseq:XP_011532583.1|refseq:XP_011532585.1|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006914"(autophagy)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0035612"(AP-2 adaptor complex binding)|ensembl:ENSG00000131374(gene)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042594"(response to starvation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1905394"(retromer complex binding)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|mint:Q92609|rcsb pdb:5GTU|ensembl:ENST00000253692(transcript)|ensembl:ENST00000429383(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|refseq:NP_001127853.1|refseq:XP_006713493.1|refseq:XP_016863041.1|refseq:XP_016863042.1|refseq:XP_016863043.1|refseq:XP_016863044.1|refseq:XP_016863045.1|refseq:XP_016863046.1	refseq:NP_057310.1|refseq:NP_476528.1|ensembl:ENSG00000111237(gene)|ensembl:ENST00000549578(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|rcsb pdb:1W24|rcsb pdb:2R17|rcsb pdb:5GTU|rcsb pdb:5OSH|rcsb pdb:5OSI|rcsb pdb:5WYH|rcsb pdb:7BLN|reactome:R-HSA-3238698|dip:DIP-29077N	-	-	-	figure legend:5c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2017/08/29	rogid:GZ7WP4suMiSPSAJK0TZWQMQZxzU9606	rogid:xjo28jAH7expkdli0DENjzLXpjw9606	intact-crc:103C5A94161B8C0C|rigid:fbM5dWEPZrc9WwLHfQoVikkVBLk	false	green fluorescent protein tag:?-?|mutation:169-169,204-204	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q92609	uniprotkb:O75436	intact:EBI-742381|uniprotkb:A6NP25|intact:EBI-28978959|ensembl:ENSP00000253692|ensembl:ENSP00000398127|uniprotkb:C9JP52	intact:EBI-1043891|uniprotkb:Q8TBH4|uniprotkb:Q9H982|ensembl:ENSP00000263559|ensembl:ENSP00000362480|uniprotkb:B2RDD3|uniprotkb:A8MZ56	psi-mi:tbcd5_human(display_long)|uniprotkb:TBC1D5(gene name)|psi-mi:TBC1D5(display_short)|uniprotkb:KIAA0210(gene name synonym)	psi-mi:vp26a_human(display_long)|uniprotkb:VPS26A(gene name)|psi-mi:VPS26A(display_short)|uniprotkb:VPS26(gene name synonym)|uniprotkb:Vesicle protein sorting 26A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846549|imex:IM-26126-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000253692|ensembl:ENSP00000398127|ensembl:ENSP00000402935|ensembl:ENST00000446818|refseq:NP_055559.1|refseq:XP_011532586.1|refseq:XP_011532583.1|refseq:XP_011532585.1|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006914"(autophagy)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0035612"(AP-2 adaptor complex binding)|ensembl:ENSG00000131374(gene)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042594"(response to starvation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1905394"(retromer complex binding)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|mint:Q92609|rcsb pdb:5GTU|ensembl:ENST00000253692(transcript)|ensembl:ENST00000429383(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|refseq:NP_001127853.1|refseq:XP_006713493.1|refseq:XP_016863041.1|refseq:XP_016863042.1|refseq:XP_016863043.1|refseq:XP_016863044.1|refseq:XP_016863045.1|refseq:XP_016863046.1	ensembl:ENSG00000122958(gene)|ensembl:ENST00000263559(transcript)|ensembl:ENST00000373382(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031982"(vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0097422"(tubular endosome)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR028934|mint:O75436|rcsb pdb:2FAU|rcsb pdb:5F0J|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|reactome:R-HSA-3238698|rcsb pdb:7BLO|refseq:NP_001030337.1|refseq:NP_004887.2|refseq:NP_001305875.1|dip:DIP-29075N	-	-	-	figure legend:5c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2017/08/29	rogid:GZ7WP4suMiSPSAJK0TZWQMQZxzU9606	rogid:n0uOd+2HQmRW7koIy678uP0d3+o9606	intact-crc:103C5A94161B8C0C|rigid:fbM5dWEPZrc9WwLHfQoVikkVBLk	false	green fluorescent protein tag:?-?|mutation:169-169,204-204	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q92609	uniprotkb:Q96QK1	intact:EBI-742381|uniprotkb:A6NP25|intact:EBI-28978959|ensembl:ENSP00000253692|ensembl:ENSP00000398127|uniprotkb:C9JP52	intact:EBI-1054634|uniprotkb:Q561W2|uniprotkb:Q9H016|uniprotkb:Q9H096|uniprotkb:Q9H4P3|uniprotkb:Q9H8J0|uniprotkb:Q9NRS7|uniprotkb:Q9NVG2|uniprotkb:Q9NX80|uniprotkb:Q9NZK2|ensembl:ENSP00000299138	psi-mi:tbcd5_human(display_long)|uniprotkb:TBC1D5(gene name)|psi-mi:TBC1D5(display_short)|uniprotkb:KIAA0210(gene name synonym)	psi-mi:vps35_human(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:VPS35(gene name)|psi-mi:VPS35(display_short)|uniprotkb:MEM3(gene name synonym)|uniprotkb:TCCCTA00141(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846549|imex:IM-26126-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000253692|ensembl:ENSP00000398127|ensembl:ENSP00000402935|ensembl:ENST00000446818|refseq:NP_055559.1|refseq:XP_011532586.1|refseq:XP_011532583.1|refseq:XP_011532585.1|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006914"(autophagy)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0035612"(AP-2 adaptor complex binding)|ensembl:ENSG00000131374(gene)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042594"(response to starvation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1905394"(retromer complex binding)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|mint:Q92609|rcsb pdb:5GTU|ensembl:ENST00000253692(transcript)|ensembl:ENST00000429383(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|refseq:NP_001127853.1|refseq:XP_006713493.1|refseq:XP_016863041.1|refseq:XP_016863042.1|refseq:XP_016863043.1|refseq:XP_016863044.1|refseq:XP_016863045.1|refseq:XP_016863046.1	refseq:NP_060676.2|rcsb pdb:5F0J|rcsb pdb:5F0K|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|rcsb pdb:5OSH|rcsb pdb:5OSI|rcsb pdb:7BLN|rcsb pdb:7BLO|reactome:R-HSA-3238698|ensembl:ENSG00000069329(gene)|ensembl:ENST00000299138(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0097422"(tubular endosome)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|rcsb pdb:2R17|dip:DIP-29076N	-	-	-	figure legend:5c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2017/08/29	rogid:GZ7WP4suMiSPSAJK0TZWQMQZxzU9606	rogid:EXkMduDQKNCdp876vGF5vna9t389606	intact-crc:103C5A94161B8C0C|rigid:fbM5dWEPZrc9WwLHfQoVikkVBLk	false	green fluorescent protein tag:?-?|mutation:169-169,204-204	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q92609	uniprotkb:Q4G0F5	intact:EBI-742381|uniprotkb:A6NP25|intact:EBI-28978959|ensembl:ENSP00000253692|ensembl:ENSP00000398127|uniprotkb:C9JP52	intact:EBI-6151831|uniprotkb:Q96A55|ensembl:ENSP00000281187|ensembl:ENSP00000434162	psi-mi:tbcd5_human(display_long)|uniprotkb:TBC1D5(gene name)|psi-mi:TBC1D5(display_short)|uniprotkb:KIAA0210(gene name synonym)	psi-mi:vp26b_human(display_long)|uniprotkb:Vesicle protein sorting 26B(gene name synonym)|uniprotkb:VPS26B(gene name)|psi-mi:VPS26B(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846549|imex:IM-26126-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000253692|ensembl:ENSP00000398127|ensembl:ENSP00000402935|ensembl:ENST00000446818|refseq:NP_055559.1|refseq:XP_011532586.1|refseq:XP_011532583.1|refseq:XP_011532585.1|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006914"(autophagy)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0035612"(AP-2 adaptor complex binding)|ensembl:ENSG00000131374(gene)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042594"(response to starvation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1905394"(retromer complex binding)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|mint:Q92609|rcsb pdb:5GTU|ensembl:ENST00000253692(transcript)|ensembl:ENST00000429383(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|refseq:NP_001127853.1|refseq:XP_006713493.1|refseq:XP_016863041.1|refseq:XP_016863042.1|refseq:XP_016863043.1|refseq:XP_016863044.1|refseq:XP_016863045.1|refseq:XP_016863046.1	refseq:NP_443107.1|ensembl:ENSG00000151502(gene)|ensembl:ENST00000281187(transcript)|ensembl:ENST00000525095(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR028934	-	-	-	figure legend:5c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2017/08/29	rogid:GZ7WP4suMiSPSAJK0TZWQMQZxzU9606	rogid:8NQBMiFKQXjWM4/Vy7swv2pW0V89606	intact-crc:103C5A94161B8C0C|rigid:fbM5dWEPZrc9WwLHfQoVikkVBLk	false	green fluorescent protein tag:?-?|mutation:169-169,204-204	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9QZ88	uniprotkb:O75436	intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020	intact:EBI-1043891|uniprotkb:Q8TBH4|uniprotkb:Q9H982|ensembl:ENSP00000263559|ensembl:ENSP00000362480|uniprotkb:B2RDD3|uniprotkb:A8MZ56	psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym)	psi-mi:vp26a_human(display_long)|uniprotkb:VPS26A(gene name)|psi-mi:VPS26A(display_short)|uniprotkb:VPS26(gene name synonym)|uniprotkb:Vesicle protein sorting 26A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846587|imex:IM-26126-27	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome)	ensembl:ENSG00000122958(gene)|ensembl:ENST00000263559(transcript)|ensembl:ENST00000373382(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031982"(vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0097422"(tubular endosome)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR028934|mint:O75436|rcsb pdb:2FAU|rcsb pdb:5F0J|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|reactome:R-HSA-3238698|rcsb pdb:7BLO|refseq:NP_001030337.1|refseq:NP_004887.2|refseq:NP_001305875.1|dip:DIP-29075N	-	function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint	-	figure legend:5C, Supp. table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2018/09/18	rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090	rogid:n0uOd+2HQmRW7koIy678uP0d3+o9606	intact-crc:277143327AF5FB10|rigid:7UNlQ8AlX7K70HlMO4VhJHdAUC0	false	green fluorescent protein tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9QZ88	uniprotkb:Q5T1M5	intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020	intact:EBI-5235934|uniprotkb:Q05DK8|uniprotkb:Q5T1M2|uniprotkb:Q6DD85|uniprotkb:Q9Y4D0|ensembl:ENSP00000238256|ensembl:ENSP00000416158	psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym)	psi-mi:fkb15_human(display_long)|uniprotkb:FKBP15(gene name)|psi-mi:FKBP15(display_short)|uniprotkb:KIAA0674(gene name synonym)|uniprotkb:133 kDa FK506-binding protein(gene name synonym)|uniprotkb:WASP- and FKBP-like protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846587|imex:IM-26126-27	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome)	refseq:NP_056073.1|refseq:XP_006717081.1|ensembl:ENSG00000119321(gene)|ensembl:ENST00000238256(transcript)|ensembl:ENST00000446284(transcript)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0003779"(actin binding)|go:"GO:0005769"(early endosome)|go:"GO:0006897"(endocytosis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030426"(growth cone)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|mint:Q5T1M5	-	function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint	-	figure legend:5C, Supp. table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2018/09/18	rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090	rogid:2th35ZHTzidVTyWGpc0Emz3foIY9606	intact-crc:277143327AF5FB10|rigid:7UNlQ8AlX7K70HlMO4VhJHdAUC0	false	green fluorescent protein tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9QZ88	uniprotkb:Q9NQA3	intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020	intact:EBI-9846564|uniprotkb:A6NGF1|uniprotkb:Q8N305|intact:EBI-28979423	psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym)	psi-mi:wash6_human(display_long)|uniprotkb:WASH6P(gene name)|psi-mi:WASH6P(display_short)|uniprotkb:CXYorf1(gene name synonym)|uniprotkb:FAM39A(gene name synonym)|uniprotkb:Protein FAM39A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846587|imex:IM-26126-27	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome)	interpro:IPR028290|interpro:IPR021854|mint:Q9NQA3|go:"GO:0003779"(actin binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0016197"(endosomal transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071203"(WASH complex)	-	function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint	-	figure legend:5C, Supp. table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2018/09/18	rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090	rogid:WFinmhG9sW8cuYKHW5sitOj6a9k9606	intact-crc:277143327AF5FB10|rigid:7UNlQ8AlX7K70HlMO4VhJHdAUC0	false	green fluorescent protein tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9QZ88	uniprotkb:Q9Y4E1	intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020	intact:EBI-948957|intact:EBI-28970026|ensembl:ENSP00000363482|uniprotkb:Q5SQU4|uniprotkb:Q5SQU5|uniprotkb:Q7L521|uniprotkb:Q9UG79|intact:EBI-2563814|uniprotkb:B4DZQ6|uniprotkb:B9EK53|uniprotkb:F5H0J6|uniprotkb:F5H871	psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym)	psi-mi:wac2c_human(display_long)|uniprotkb:VPEF(gene name synonym)|uniprotkb:WASHC2C(gene name)|psi-mi:WASHC2C(display_short)|uniprotkb:FAM21C(gene name synonym)|uniprotkb:KIAA0592(gene name synonym)|uniprotkb:Vaccinia virus penetration factor(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846587|imex:IM-26126-27	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome)	ensembl:ENSG00000172661(gene)|ensembl:ENST00000374362(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0015031"(protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032456"(endocytic recycling)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0071203"(WASH complex)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1900024"(regulation of substrate adhesion-dependent cell spreading)|go:"GO:1905394"(retromer complex binding)|go:"GO:2000813"(negative regulation of barbed-end actin filament capping)|interpro:IPR029341|mint:Q9Y4E1|ensembl:ENST00000540872|ensembl:ENSP00000439811|ensembl:ENSP00000363482|ensembl:ENST00000537517|ensembl:ENSP00000442128|refseq:NP_001162577.1|refseq:NP_001162578.1|refseq:NP_056077.2	-	function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint	-	figure legend:5C, Supp. table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2018/09/18	rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090	rogid:gUK2aPVIQiHey/Wka1mgFuBTKNE9606	intact-crc:277143327AF5FB10|rigid:7UNlQ8AlX7K70HlMO4VhJHdAUC0	false	green fluorescent protein tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9QZ88	uniprotkb:Q2M389	intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020	intact:EBI-2563783|uniprotkb:Q8IW61|uniprotkb:Q9NVD6|uniprotkb:Q8N5W7|uniprotkb:Q2NL83|uniprotkb:Q9UPW7|ensembl:ENSP00000328062	psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym)	psi-mi:wasc4_human(display_long)|uniprotkb:WASHC4(gene name)|psi-mi:WASHC4(display_short)|uniprotkb:KIAA1033(gene name synonym)|uniprotkb:Strumpellin and WASH-interacting protein(gene name synonym)|uniprotkb:WASH complex subunit SWIP(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846587|imex:IM-26126-27	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome)	refseq:NP_056090.1|ensembl:ENSG00000136051(gene)|ensembl:ENST00000332180(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0007032"(endosome organization)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0071203"(WASH complex)|go:"GO:0140591"(nuclear envelope budding)|interpro:IPR027307|interpro:IPR028191|interpro:IPR028283|interpro:IPR028282|refseq:NP_001280569.1	-	function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint	-	figure legend:5C, Supp. table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2018/09/18	rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090	rogid:APnP9mxAqwzKEoQFGt94Z8Y73t49606	intact-crc:277143327AF5FB10|rigid:7UNlQ8AlX7K70HlMO4VhJHdAUC0	false	green fluorescent protein tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9QZ88	uniprotkb:Q9UBQ0	intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020	intact:EBI-718596|uniprotkb:Q502Y5|uniprotkb:Q9H0W0|uniprotkb:Q9NRP1|uniprotkb:Q6FIF8|uniprotkb:Q6IAH3|uniprotkb:Q9NRU7|ensembl:ENSP00000447058	psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym)	psi-mi:vps29_human(display_long)|uniprotkb:Vesicle protein sorting 29(gene name synonym)|uniprotkb:PEP11 homolog(gene name synonym)|uniprotkb:VPS29(gene name)|psi-mi:VPS29(display_short)|uniprotkb:DC7(orf name)|uniprotkb:DC15(orf name)|uniprotkb:MDS007(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846587|imex:IM-26126-27	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome)	refseq:NP_057310.1|refseq:NP_476528.1|ensembl:ENSG00000111237(gene)|ensembl:ENST00000549578(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|rcsb pdb:1W24|rcsb pdb:2R17|rcsb pdb:5GTU|rcsb pdb:5OSH|rcsb pdb:5OSI|rcsb pdb:5WYH|rcsb pdb:7BLN|reactome:R-HSA-3238698|dip:DIP-29077N	-	function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint	-	figure legend:5C, Supp. table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2018/09/18	rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090	rogid:xjo28jAH7expkdli0DENjzLXpjw9606	intact-crc:277143327AF5FB10|rigid:7UNlQ8AlX7K70HlMO4VhJHdAUC0	false	green fluorescent protein tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9QZ88	uniprotkb:Q96QK1	intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020	intact:EBI-1054634|uniprotkb:Q561W2|uniprotkb:Q9H016|uniprotkb:Q9H096|uniprotkb:Q9H4P3|uniprotkb:Q9H8J0|uniprotkb:Q9NRS7|uniprotkb:Q9NVG2|uniprotkb:Q9NX80|uniprotkb:Q9NZK2|ensembl:ENSP00000299138	psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym)	psi-mi:vps35_human(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:VPS35(gene name)|psi-mi:VPS35(display_short)|uniprotkb:MEM3(gene name synonym)|uniprotkb:TCCCTA00141(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846587|imex:IM-26126-27	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome)	refseq:NP_060676.2|rcsb pdb:5F0J|rcsb pdb:5F0K|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|rcsb pdb:5OSH|rcsb pdb:5OSI|rcsb pdb:7BLN|rcsb pdb:7BLO|reactome:R-HSA-3238698|ensembl:ENSG00000069329(gene)|ensembl:ENST00000299138(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0097422"(tubular endosome)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|rcsb pdb:2R17|dip:DIP-29076N	-	function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint	-	figure legend:5C, Supp. table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2018/09/18	rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090	rogid:EXkMduDQKNCdp876vGF5vna9t389606	intact-crc:277143327AF5FB10|rigid:7UNlQ8AlX7K70HlMO4VhJHdAUC0	false	green fluorescent protein tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9QZ88	uniprotkb:Q92609	intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020	intact:EBI-742381|uniprotkb:A6NP25|intact:EBI-28978959|ensembl:ENSP00000253692|ensembl:ENSP00000398127|uniprotkb:C9JP52	psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym)	psi-mi:tbcd5_human(display_long)|uniprotkb:TBC1D5(gene name)|psi-mi:TBC1D5(display_short)|uniprotkb:KIAA0210(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846587|imex:IM-26126-27	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome)	ensembl:ENSP00000253692|ensembl:ENSP00000398127|ensembl:ENSP00000402935|ensembl:ENST00000446818|refseq:NP_055559.1|refseq:XP_011532586.1|refseq:XP_011532583.1|refseq:XP_011532585.1|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006914"(autophagy)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0035612"(AP-2 adaptor complex binding)|ensembl:ENSG00000131374(gene)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042594"(response to starvation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1905394"(retromer complex binding)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|mint:Q92609|rcsb pdb:5GTU|ensembl:ENST00000253692(transcript)|ensembl:ENST00000429383(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|refseq:NP_001127853.1|refseq:XP_006713493.1|refseq:XP_016863041.1|refseq:XP_016863042.1|refseq:XP_016863043.1|refseq:XP_016863044.1|refseq:XP_016863045.1|refseq:XP_016863046.1	-	function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint	-	figure legend:5C, Supp. table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2018/09/18	rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090	rogid:GZ7WP4suMiSPSAJK0TZWQMQZxzU9606	intact-crc:277143327AF5FB10|rigid:7UNlQ8AlX7K70HlMO4VhJHdAUC0	false	green fluorescent protein tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9QZ88	uniprotkb:Q4G0F5	intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020	intact:EBI-6151831|uniprotkb:Q96A55|ensembl:ENSP00000281187|ensembl:ENSP00000434162	psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym)	psi-mi:vp26b_human(display_long)|uniprotkb:Vesicle protein sorting 26B(gene name synonym)|uniprotkb:VPS26B(gene name)|psi-mi:VPS26B(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846587|imex:IM-26126-27	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome)	refseq:NP_443107.1|ensembl:ENSG00000151502(gene)|ensembl:ENST00000281187(transcript)|ensembl:ENST00000525095(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR028934	-	function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint	-	figure legend:5C, Supp. table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2018/09/18	rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090	rogid:8NQBMiFKQXjWM4/Vy7swv2pW0V89606	intact-crc:277143327AF5FB10|rigid:7UNlQ8AlX7K70HlMO4VhJHdAUC0	false	green fluorescent protein tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9QZ88	uniprotkb:Q6VEQ5	intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020	intact:EBI-2870122|intact:EBI-28987462	psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym)	psi-mi:wash2_human(display_long)|uniprotkb:WASH2P(gene name)|psi-mi:WASH2P(display_short)|uniprotkb:FAM39B(gene name synonym)|uniprotkb:CXYorf1-like protein on chromosome 2(gene name synonym)|uniprotkb:Protein FAM39B(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846611|imex:IM-26126-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome)	interpro:IPR021854|interpro:IPR003124(Actin-binding WH2)|interpro:IPR028290|go:"GO:0003779"(actin binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071203"(WASH complex)	-	function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint	-	figure legend:5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2018/09/18	rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090	rogid:Z6cVOs2syJXIbtDBZ6LM6d/fsew9606	intact-crc:FFD4D35E09E49872|rigid:VrnrOmVxC9uPrQekErvFrdDp7PA	false	green fluorescent protein tag:c-c|mutation:152-152	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9QZ88	uniprotkb:Q9UBQ0	intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020	intact:EBI-718596|uniprotkb:Q502Y5|uniprotkb:Q9H0W0|uniprotkb:Q9NRP1|uniprotkb:Q6FIF8|uniprotkb:Q6IAH3|uniprotkb:Q9NRU7|ensembl:ENSP00000447058	psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym)	psi-mi:vps29_human(display_long)|uniprotkb:Vesicle protein sorting 29(gene name synonym)|uniprotkb:PEP11 homolog(gene name synonym)|uniprotkb:VPS29(gene name)|psi-mi:VPS29(display_short)|uniprotkb:DC7(orf name)|uniprotkb:DC15(orf name)|uniprotkb:MDS007(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846611|imex:IM-26126-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome)	refseq:NP_057310.1|refseq:NP_476528.1|ensembl:ENSG00000111237(gene)|ensembl:ENST00000549578(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|rcsb pdb:1W24|rcsb pdb:2R17|rcsb pdb:5GTU|rcsb pdb:5OSH|rcsb pdb:5OSI|rcsb pdb:5WYH|rcsb pdb:7BLN|reactome:R-HSA-3238698|dip:DIP-29077N	-	function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint	-	figure legend:5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2018/09/18	rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090	rogid:xjo28jAH7expkdli0DENjzLXpjw9606	intact-crc:FFD4D35E09E49872|rigid:VrnrOmVxC9uPrQekErvFrdDp7PA	false	green fluorescent protein tag:c-c|mutation:152-152	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9QZ88	uniprotkb:Q2M389	intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020	intact:EBI-2563783|uniprotkb:Q8IW61|uniprotkb:Q9NVD6|uniprotkb:Q8N5W7|uniprotkb:Q2NL83|uniprotkb:Q9UPW7|ensembl:ENSP00000328062	psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym)	psi-mi:wasc4_human(display_long)|uniprotkb:WASHC4(gene name)|psi-mi:WASHC4(display_short)|uniprotkb:KIAA1033(gene name synonym)|uniprotkb:Strumpellin and WASH-interacting protein(gene name synonym)|uniprotkb:WASH complex subunit SWIP(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846611|imex:IM-26126-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome)	refseq:NP_056090.1|ensembl:ENSG00000136051(gene)|ensembl:ENST00000332180(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0007032"(endosome organization)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0071203"(WASH complex)|go:"GO:0140591"(nuclear envelope budding)|interpro:IPR027307|interpro:IPR028191|interpro:IPR028283|interpro:IPR028282|refseq:NP_001280569.1	-	function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint	-	figure legend:5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2018/09/18	rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090	rogid:APnP9mxAqwzKEoQFGt94Z8Y73t49606	intact-crc:FFD4D35E09E49872|rigid:VrnrOmVxC9uPrQekErvFrdDp7PA	false	green fluorescent protein tag:c-c|mutation:152-152	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9QZ88	uniprotkb:Q12768	intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020	intact:EBI-2563794|uniprotkb:A8K4R7|uniprotkb:Q3KQX5|uniprotkb:Q8TBQ2|ensembl:ENSP00000318016	psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym)	psi-mi:wasc5_human(display_long)|uniprotkb:WASHC5(gene name)|psi-mi:WASHC5(display_short)|uniprotkb:KIAA0196(gene name synonym)|uniprotkb:Strumpellin(gene name synonym)|uniprotkb:WASH complex subunit strumpellin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846611|imex:IM-26126-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome)	refseq:NP_055661.3|ensembl:ENSG00000164961(gene)|ensembl:ENST00000318410(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0034629"|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051125"(regulation of actin nucleation)|go:"GO:0071203"(WASH complex)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0097494"(regulation of vesicle size)|go:"GO:0140285"(endosome fission)|interpro:IPR019393|mint:Q12768|refseq:XP_016869602.1	-	function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint	-	figure legend:5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2018/09/18	rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090	rogid:9QEw0Z7NIOvpVJtWXcLp67ApJdk9606	intact-crc:FFD4D35E09E49872|rigid:VrnrOmVxC9uPrQekErvFrdDp7PA	false	green fluorescent protein tag:c-c|mutation:152-152	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9QZ88	uniprotkb:O75436	intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020	intact:EBI-1043891|uniprotkb:Q8TBH4|uniprotkb:Q9H982|ensembl:ENSP00000263559|ensembl:ENSP00000362480|uniprotkb:B2RDD3|uniprotkb:A8MZ56	psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym)	psi-mi:vp26a_human(display_long)|uniprotkb:VPS26A(gene name)|psi-mi:VPS26A(display_short)|uniprotkb:VPS26(gene name synonym)|uniprotkb:Vesicle protein sorting 26A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846611|imex:IM-26126-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome)	ensembl:ENSG00000122958(gene)|ensembl:ENST00000263559(transcript)|ensembl:ENST00000373382(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031982"(vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0097422"(tubular endosome)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR028934|mint:O75436|rcsb pdb:2FAU|rcsb pdb:5F0J|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|reactome:R-HSA-3238698|rcsb pdb:7BLO|refseq:NP_001030337.1|refseq:NP_004887.2|refseq:NP_001305875.1|dip:DIP-29075N	-	function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint	-	figure legend:5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2018/09/18	rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090	rogid:n0uOd+2HQmRW7koIy678uP0d3+o9606	intact-crc:FFD4D35E09E49872|rigid:VrnrOmVxC9uPrQekErvFrdDp7PA	false	green fluorescent protein tag:c-c|mutation:152-152	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9QZ88	uniprotkb:Q4G0F5	intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020	intact:EBI-6151831|uniprotkb:Q96A55|ensembl:ENSP00000281187|ensembl:ENSP00000434162	psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym)	psi-mi:vp26b_human(display_long)|uniprotkb:Vesicle protein sorting 26B(gene name synonym)|uniprotkb:VPS26B(gene name)|psi-mi:VPS26B(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846611|imex:IM-26126-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome)	refseq:NP_443107.1|ensembl:ENSG00000151502(gene)|ensembl:ENST00000281187(transcript)|ensembl:ENST00000525095(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR028934	-	function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint	-	figure legend:5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2018/09/18	rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090	rogid:8NQBMiFKQXjWM4/Vy7swv2pW0V89606	intact-crc:FFD4D35E09E49872|rigid:VrnrOmVxC9uPrQekErvFrdDp7PA	false	green fluorescent protein tag:c-c|mutation:152-152	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9QZ88	uniprotkb:Q5T1M5	intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020	intact:EBI-5235934|uniprotkb:Q05DK8|uniprotkb:Q5T1M2|uniprotkb:Q6DD85|uniprotkb:Q9Y4D0|ensembl:ENSP00000238256|ensembl:ENSP00000416158	psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym)	psi-mi:fkb15_human(display_long)|uniprotkb:FKBP15(gene name)|psi-mi:FKBP15(display_short)|uniprotkb:KIAA0674(gene name synonym)|uniprotkb:133 kDa FK506-binding protein(gene name synonym)|uniprotkb:WASP- and FKBP-like protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846611|imex:IM-26126-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome)	refseq:NP_056073.1|refseq:XP_006717081.1|ensembl:ENSG00000119321(gene)|ensembl:ENST00000238256(transcript)|ensembl:ENST00000446284(transcript)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0003779"(actin binding)|go:"GO:0005769"(early endosome)|go:"GO:0006897"(endocytosis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030426"(growth cone)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|mint:Q5T1M5	-	function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint	-	figure legend:5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2018/09/18	rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090	rogid:2th35ZHTzidVTyWGpc0Emz3foIY9606	intact-crc:FFD4D35E09E49872|rigid:VrnrOmVxC9uPrQekErvFrdDp7PA	false	green fluorescent protein tag:c-c|mutation:152-152	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9QZ88	uniprotkb:P47756	intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020	intact:EBI-353595|uniprotkb:Q5U0L4|uniprotkb:Q8TB49|uniprotkb:Q9NUC4|uniprotkb:Q32Q68|ensembl:ENSP00000364284|ensembl:ENSP00000501528	psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym)	psi-mi:capzb_human(display_long)|uniprotkb:CAPZB(gene name)|psi-mi:CAPZB(display_short)|uniprotkb:CapZ beta(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846611|imex:IM-26126-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome)	refseq:NP_001193469.1|refseq:NP_004921.1|go:"GO:0045296"(cadherin binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051490"(negative regulation of filopodium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071203"(WASH complex)|go:"GO:0097224"(sperm connecting piece)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|interpro:IPR001698(F-actin capping protein, beta subunit)|interpro:IPR019771|interpro:IPR037282|interpro:IPR042276|interpro:IPR043175|mint:P47756|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-9013405|reactome:R-HSA-9035034|reactome:R-HSA-9662360|reactome:R-HSA-983231|ensembl:ENSG00000077549(gene)|ensembl:ENST00000375142(transcript)|ensembl:ENST00000674432(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005903"(brush border)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030863"(cortical cytoskeleton)|refseq:NP_001269091.1	-	function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint	-	figure legend:5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2018/09/18	rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090	rogid:qRXsrB2fLT1DMVIVRWKFYe4Aln49606	intact-crc:FFD4D35E09E49872|rigid:VrnrOmVxC9uPrQekErvFrdDp7PA	false	green fluorescent protein tag:c-c|mutation:152-152	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9QZ88	uniprotkb:Q9Y4E1	intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020	intact:EBI-948957|intact:EBI-28970026|ensembl:ENSP00000363482|uniprotkb:Q5SQU4|uniprotkb:Q5SQU5|uniprotkb:Q7L521|uniprotkb:Q9UG79|intact:EBI-2563814|uniprotkb:B4DZQ6|uniprotkb:B9EK53|uniprotkb:F5H0J6|uniprotkb:F5H871	psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym)	psi-mi:wac2c_human(display_long)|uniprotkb:VPEF(gene name synonym)|uniprotkb:WASHC2C(gene name)|psi-mi:WASHC2C(display_short)|uniprotkb:FAM21C(gene name synonym)|uniprotkb:KIAA0592(gene name synonym)|uniprotkb:Vaccinia virus penetration factor(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846611|imex:IM-26126-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome)	ensembl:ENSG00000172661(gene)|ensembl:ENST00000374362(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0015031"(protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032456"(endocytic recycling)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0071203"(WASH complex)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1900024"(regulation of substrate adhesion-dependent cell spreading)|go:"GO:1905394"(retromer complex binding)|go:"GO:2000813"(negative regulation of barbed-end actin filament capping)|interpro:IPR029341|mint:Q9Y4E1|ensembl:ENST00000540872|ensembl:ENSP00000439811|ensembl:ENSP00000363482|ensembl:ENST00000537517|ensembl:ENSP00000442128|refseq:NP_001162577.1|refseq:NP_001162578.1|refseq:NP_056077.2	-	function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint	-	figure legend:5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2018/09/18	rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090	rogid:gUK2aPVIQiHey/Wka1mgFuBTKNE9606	intact-crc:FFD4D35E09E49872|rigid:VrnrOmVxC9uPrQekErvFrdDp7PA	false	green fluorescent protein tag:c-c|mutation:152-152	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9QZ88	uniprotkb:Q641Q2	intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020	intact:EBI-2870155|intact:EBI-4401456|uniprotkb:A2A3S2|uniprotkb:A2A3U6|uniprotkb:Q5SNT6|uniprotkb:Q6DHY0|intact:EBI-28969894|ensembl:ENSP00000282633	psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym)	psi-mi:wac2a_human(display_long)|uniprotkb:WASHC2A(gene name)|psi-mi:WASHC2A(display_short)|uniprotkb:FAM21A(gene name synonym)|uniprotkb:FAM21B(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846611|imex:IM-26126-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome)	ensembl:ENSP00000282633|ensembl:ENST00000351071|ensembl:ENSP00000344037|refseq:NP_001005751.1|refseq:NP_001278327.1|ensembl:ENSG00000099290(gene)|ensembl:ENST00000282633(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008289"(lipid binding)|go:"GO:0015031"(protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071203"(WASH complex)|interpro:IPR029341|mint:Q641Q2|go:"GO:0005769"(early endosome)	-	function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint	-	figure legend:5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2018/09/18	rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090	rogid:JtzABQxJJmBcNqKPsm/t5KJa2Lw9606	intact-crc:FFD4D35E09E49872|rigid:VrnrOmVxC9uPrQekErvFrdDp7PA	false	green fluorescent protein tag:c-c|mutation:152-152	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9QZ88	uniprotkb:Q96QK1	intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020	intact:EBI-1054634|uniprotkb:Q561W2|uniprotkb:Q9H016|uniprotkb:Q9H096|uniprotkb:Q9H4P3|uniprotkb:Q9H8J0|uniprotkb:Q9NRS7|uniprotkb:Q9NVG2|uniprotkb:Q9NX80|uniprotkb:Q9NZK2|ensembl:ENSP00000299138	psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym)	psi-mi:vps35_human(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:VPS35(gene name)|psi-mi:VPS35(display_short)|uniprotkb:MEM3(gene name synonym)|uniprotkb:TCCCTA00141(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846611|imex:IM-26126-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome)	refseq:NP_060676.2|rcsb pdb:5F0J|rcsb pdb:5F0K|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|rcsb pdb:5OSH|rcsb pdb:5OSI|rcsb pdb:7BLN|rcsb pdb:7BLO|reactome:R-HSA-3238698|ensembl:ENSG00000069329(gene)|ensembl:ENST00000299138(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0097422"(tubular endosome)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|rcsb pdb:2R17|dip:DIP-29076N	-	function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint	-	figure legend:5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2018/09/18	rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090	rogid:EXkMduDQKNCdp876vGF5vna9t389606	intact-crc:FFD4D35E09E49872|rigid:VrnrOmVxC9uPrQekErvFrdDp7PA	false	green fluorescent protein tag:c-c|mutation:152-152	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9QZ88	uniprotkb:P47755	intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020	intact:EBI-762451|uniprotkb:B4DG50|ensembl:ENSP00000354947	psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym)	psi-mi:caza2_human(display_long)|uniprotkb:CapZ alpha-2(gene name synonym)|uniprotkb:CAPZA2(gene name)|psi-mi:CAPZA2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846611|imex:IM-26126-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome)	refseq:NP_006127.1|ensembl:ENSG00000198898(gene)|ensembl:ENST00000361183(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002189(F-actin capping protein, alpha subunit)|interpro:IPR017865|interpro:IPR037282|interpro:IPR042276|interpro:IPR042489|mint:P47755|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-879415|reactome:R-HSA-9662360|reactome:R-HSA-983231|go:"GO:0016020"(membrane)	-	function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint	-	figure legend:5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2018/09/18	rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090	rogid:7+0w8fJ0OowIwAC7/tdNqiGSepc9606	intact-crc:FFD4D35E09E49872|rigid:VrnrOmVxC9uPrQekErvFrdDp7PA	false	green fluorescent protein tag:c-c|mutation:152-152	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9EQH3	uniprotkb:O75436	intact:EBI-775825|uniprotkb:Q61123|ensembl:ENSMUSP00000034131	intact:EBI-1043891|uniprotkb:Q8TBH4|uniprotkb:Q9H982|ensembl:ENSP00000263559|ensembl:ENSP00000362480|uniprotkb:B2RDD3|uniprotkb:A8MZ56	psi-mi:vps35_mouse(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:Vps35(gene name)|psi-mi:Vps35(display_short)|uniprotkb:Mem3(gene name synonym)	psi-mi:vp26a_human(display_long)|uniprotkb:VPS26A(gene name)|psi-mi:VPS26A(display_short)|uniprotkb:VPS26(gene name synonym)|uniprotkb:Vesicle protein sorting 26A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846643|imex:IM-26126-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_075373.1|dip:DIP-32210N|ensembl:ENSMUSG00000031696(gene)|ensembl:ENSMUST00000034131(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006624"(vacuolar protein processing)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007416"(synapse assembly)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032463"(negative regulation of protein homooligomerization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090326"(positive regulation of locomotion involved in locomotory behavior)|go:"GO:0097422"(tubular endosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903181"(positive regulation of dopamine biosynthetic process)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903828"(negative regulation of protein localization)|go:"GO:1905166"(negative regulation of lysosomal protein catabolic process)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|mint:Q9EQH3|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698	ensembl:ENSG00000122958(gene)|ensembl:ENST00000263559(transcript)|ensembl:ENST00000373382(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031982"(vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0097422"(tubular endosome)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR028934|mint:O75436|rcsb pdb:2FAU|rcsb pdb:5F0J|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|reactome:R-HSA-3238698|rcsb pdb:7BLO|refseq:NP_001030337.1|refseq:NP_004887.2|refseq:NP_001305875.1|dip:DIP-29075N	-	-	-	figure legend:5C, supplemental  table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2017/08/29	rogid:dK5TqSajxrGKjiNwRjeZCV519XE10090	rogid:n0uOd+2HQmRW7koIy678uP0d3+o9606	intact-crc:CF2108B52D4E653D|rigid:Y1TB380D/8n7jYy0R708j8QSP/U	false	green fluorescent protein tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9EQH3	uniprotkb:Q96QK1	intact:EBI-775825|uniprotkb:Q61123|ensembl:ENSMUSP00000034131	intact:EBI-1054634|uniprotkb:Q561W2|uniprotkb:Q9H016|uniprotkb:Q9H096|uniprotkb:Q9H4P3|uniprotkb:Q9H8J0|uniprotkb:Q9NRS7|uniprotkb:Q9NVG2|uniprotkb:Q9NX80|uniprotkb:Q9NZK2|ensembl:ENSP00000299138	psi-mi:vps35_mouse(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:Vps35(gene name)|psi-mi:Vps35(display_short)|uniprotkb:Mem3(gene name synonym)	psi-mi:vps35_human(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:VPS35(gene name)|psi-mi:VPS35(display_short)|uniprotkb:MEM3(gene name synonym)|uniprotkb:TCCCTA00141(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846643|imex:IM-26126-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_075373.1|dip:DIP-32210N|ensembl:ENSMUSG00000031696(gene)|ensembl:ENSMUST00000034131(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006624"(vacuolar protein processing)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007416"(synapse assembly)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032463"(negative regulation of protein homooligomerization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090326"(positive regulation of locomotion involved in locomotory behavior)|go:"GO:0097422"(tubular endosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903181"(positive regulation of dopamine biosynthetic process)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903828"(negative regulation of protein localization)|go:"GO:1905166"(negative regulation of lysosomal protein catabolic process)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|mint:Q9EQH3|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698	refseq:NP_060676.2|rcsb pdb:5F0J|rcsb pdb:5F0K|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|rcsb pdb:5OSH|rcsb pdb:5OSI|rcsb pdb:7BLN|rcsb pdb:7BLO|reactome:R-HSA-3238698|ensembl:ENSG00000069329(gene)|ensembl:ENST00000299138(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0097422"(tubular endosome)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|rcsb pdb:2R17|dip:DIP-29076N	-	-	-	figure legend:5C, supplemental  table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2017/08/29	rogid:dK5TqSajxrGKjiNwRjeZCV519XE10090	rogid:EXkMduDQKNCdp876vGF5vna9t389606	intact-crc:CF2108B52D4E653D|rigid:Y1TB380D/8n7jYy0R708j8QSP/U	false	green fluorescent protein tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9EQH3	uniprotkb:P47755	intact:EBI-775825|uniprotkb:Q61123|ensembl:ENSMUSP00000034131	intact:EBI-762451|uniprotkb:B4DG50|ensembl:ENSP00000354947	psi-mi:vps35_mouse(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:Vps35(gene name)|psi-mi:Vps35(display_short)|uniprotkb:Mem3(gene name synonym)	psi-mi:caza2_human(display_long)|uniprotkb:CapZ alpha-2(gene name synonym)|uniprotkb:CAPZA2(gene name)|psi-mi:CAPZA2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846643|imex:IM-26126-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_075373.1|dip:DIP-32210N|ensembl:ENSMUSG00000031696(gene)|ensembl:ENSMUST00000034131(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006624"(vacuolar protein processing)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007416"(synapse assembly)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032463"(negative regulation of protein homooligomerization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090326"(positive regulation of locomotion involved in locomotory behavior)|go:"GO:0097422"(tubular endosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903181"(positive regulation of dopamine biosynthetic process)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903828"(negative regulation of protein localization)|go:"GO:1905166"(negative regulation of lysosomal protein catabolic process)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|mint:Q9EQH3|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698	refseq:NP_006127.1|ensembl:ENSG00000198898(gene)|ensembl:ENST00000361183(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002189(F-actin capping protein, alpha subunit)|interpro:IPR017865|interpro:IPR037282|interpro:IPR042276|interpro:IPR042489|mint:P47755|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-879415|reactome:R-HSA-9662360|reactome:R-HSA-983231|go:"GO:0016020"(membrane)	-	-	-	figure legend:5C, supplemental  table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2017/08/29	rogid:dK5TqSajxrGKjiNwRjeZCV519XE10090	rogid:7+0w8fJ0OowIwAC7/tdNqiGSepc9606	intact-crc:CF2108B52D4E653D|rigid:Y1TB380D/8n7jYy0R708j8QSP/U	false	green fluorescent protein tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9EQH3	uniprotkb:Q9NQA3	intact:EBI-775825|uniprotkb:Q61123|ensembl:ENSMUSP00000034131	intact:EBI-9846564|uniprotkb:A6NGF1|uniprotkb:Q8N305|intact:EBI-28979423	psi-mi:vps35_mouse(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:Vps35(gene name)|psi-mi:Vps35(display_short)|uniprotkb:Mem3(gene name synonym)	psi-mi:wash6_human(display_long)|uniprotkb:WASH6P(gene name)|psi-mi:WASH6P(display_short)|uniprotkb:CXYorf1(gene name synonym)|uniprotkb:FAM39A(gene name synonym)|uniprotkb:Protein FAM39A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846643|imex:IM-26126-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_075373.1|dip:DIP-32210N|ensembl:ENSMUSG00000031696(gene)|ensembl:ENSMUST00000034131(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006624"(vacuolar protein processing)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007416"(synapse assembly)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032463"(negative regulation of protein homooligomerization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090326"(positive regulation of locomotion involved in locomotory behavior)|go:"GO:0097422"(tubular endosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903181"(positive regulation of dopamine biosynthetic process)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903828"(negative regulation of protein localization)|go:"GO:1905166"(negative regulation of lysosomal protein catabolic process)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|mint:Q9EQH3|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698	interpro:IPR028290|interpro:IPR021854|mint:Q9NQA3|go:"GO:0003779"(actin binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0016197"(endosomal transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071203"(WASH complex)	-	-	-	figure legend:5C, supplemental  table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2017/08/29	rogid:dK5TqSajxrGKjiNwRjeZCV519XE10090	rogid:WFinmhG9sW8cuYKHW5sitOj6a9k9606	intact-crc:CF2108B52D4E653D|rigid:Y1TB380D/8n7jYy0R708j8QSP/U	false	green fluorescent protein tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9EQH3	uniprotkb:Q9UBQ0	intact:EBI-775825|uniprotkb:Q61123|ensembl:ENSMUSP00000034131	intact:EBI-718596|uniprotkb:Q502Y5|uniprotkb:Q9H0W0|uniprotkb:Q9NRP1|uniprotkb:Q6FIF8|uniprotkb:Q6IAH3|uniprotkb:Q9NRU7|ensembl:ENSP00000447058	psi-mi:vps35_mouse(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:Vps35(gene name)|psi-mi:Vps35(display_short)|uniprotkb:Mem3(gene name synonym)	psi-mi:vps29_human(display_long)|uniprotkb:Vesicle protein sorting 29(gene name synonym)|uniprotkb:PEP11 homolog(gene name synonym)|uniprotkb:VPS29(gene name)|psi-mi:VPS29(display_short)|uniprotkb:DC7(orf name)|uniprotkb:DC15(orf name)|uniprotkb:MDS007(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846643|imex:IM-26126-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_075373.1|dip:DIP-32210N|ensembl:ENSMUSG00000031696(gene)|ensembl:ENSMUST00000034131(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006624"(vacuolar protein processing)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007416"(synapse assembly)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032463"(negative regulation of protein homooligomerization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090326"(positive regulation of locomotion involved in locomotory behavior)|go:"GO:0097422"(tubular endosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903181"(positive regulation of dopamine biosynthetic process)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903828"(negative regulation of protein localization)|go:"GO:1905166"(negative regulation of lysosomal protein catabolic process)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|mint:Q9EQH3|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698	refseq:NP_057310.1|refseq:NP_476528.1|ensembl:ENSG00000111237(gene)|ensembl:ENST00000549578(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|rcsb pdb:1W24|rcsb pdb:2R17|rcsb pdb:5GTU|rcsb pdb:5OSH|rcsb pdb:5OSI|rcsb pdb:5WYH|rcsb pdb:7BLN|reactome:R-HSA-3238698|dip:DIP-29077N	-	-	-	figure legend:5C, supplemental  table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2017/08/29	rogid:dK5TqSajxrGKjiNwRjeZCV519XE10090	rogid:xjo28jAH7expkdli0DENjzLXpjw9606	intact-crc:CF2108B52D4E653D|rigid:Y1TB380D/8n7jYy0R708j8QSP/U	false	green fluorescent protein tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9EQH3	uniprotkb:Q641Q2	intact:EBI-775825|uniprotkb:Q61123|ensembl:ENSMUSP00000034131	intact:EBI-2870155|intact:EBI-4401456|uniprotkb:A2A3S2|uniprotkb:A2A3U6|uniprotkb:Q5SNT6|uniprotkb:Q6DHY0|intact:EBI-28969894|ensembl:ENSP00000282633	psi-mi:vps35_mouse(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:Vps35(gene name)|psi-mi:Vps35(display_short)|uniprotkb:Mem3(gene name synonym)	psi-mi:wac2a_human(display_long)|uniprotkb:WASHC2A(gene name)|psi-mi:WASHC2A(display_short)|uniprotkb:FAM21A(gene name synonym)|uniprotkb:FAM21B(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846643|imex:IM-26126-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_075373.1|dip:DIP-32210N|ensembl:ENSMUSG00000031696(gene)|ensembl:ENSMUST00000034131(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006624"(vacuolar protein processing)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007416"(synapse assembly)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032463"(negative regulation of protein homooligomerization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090326"(positive regulation of locomotion involved in locomotory behavior)|go:"GO:0097422"(tubular endosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903181"(positive regulation of dopamine biosynthetic process)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903828"(negative regulation of protein localization)|go:"GO:1905166"(negative regulation of lysosomal protein catabolic process)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|mint:Q9EQH3|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698	ensembl:ENSP00000282633|ensembl:ENST00000351071|ensembl:ENSP00000344037|refseq:NP_001005751.1|refseq:NP_001278327.1|ensembl:ENSG00000099290(gene)|ensembl:ENST00000282633(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008289"(lipid binding)|go:"GO:0015031"(protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071203"(WASH complex)|interpro:IPR029341|mint:Q641Q2|go:"GO:0005769"(early endosome)	-	-	-	figure legend:5C, supplemental  table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2017/08/29	rogid:dK5TqSajxrGKjiNwRjeZCV519XE10090	rogid:JtzABQxJJmBcNqKPsm/t5KJa2Lw9606	intact-crc:CF2108B52D4E653D|rigid:Y1TB380D/8n7jYy0R708j8QSP/U	false	green fluorescent protein tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9EQH3	uniprotkb:P47756	intact:EBI-775825|uniprotkb:Q61123|ensembl:ENSMUSP00000034131	intact:EBI-353595|uniprotkb:Q5U0L4|uniprotkb:Q8TB49|uniprotkb:Q9NUC4|uniprotkb:Q32Q68|ensembl:ENSP00000364284|ensembl:ENSP00000501528	psi-mi:vps35_mouse(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:Vps35(gene name)|psi-mi:Vps35(display_short)|uniprotkb:Mem3(gene name synonym)	psi-mi:capzb_human(display_long)|uniprotkb:CAPZB(gene name)|psi-mi:CAPZB(display_short)|uniprotkb:CapZ beta(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846643|imex:IM-26126-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_075373.1|dip:DIP-32210N|ensembl:ENSMUSG00000031696(gene)|ensembl:ENSMUST00000034131(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006624"(vacuolar protein processing)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007416"(synapse assembly)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032463"(negative regulation of protein homooligomerization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090326"(positive regulation of locomotion involved in locomotory behavior)|go:"GO:0097422"(tubular endosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903181"(positive regulation of dopamine biosynthetic process)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903828"(negative regulation of protein localization)|go:"GO:1905166"(negative regulation of lysosomal protein catabolic process)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|mint:Q9EQH3|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698	refseq:NP_001193469.1|refseq:NP_004921.1|go:"GO:0045296"(cadherin binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051490"(negative regulation of filopodium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071203"(WASH complex)|go:"GO:0097224"(sperm connecting piece)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|interpro:IPR001698(F-actin capping protein, beta subunit)|interpro:IPR019771|interpro:IPR037282|interpro:IPR042276|interpro:IPR043175|mint:P47756|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-9013405|reactome:R-HSA-9035034|reactome:R-HSA-9662360|reactome:R-HSA-983231|ensembl:ENSG00000077549(gene)|ensembl:ENST00000375142(transcript)|ensembl:ENST00000674432(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005903"(brush border)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030863"(cortical cytoskeleton)|refseq:NP_001269091.1	-	-	-	figure legend:5C, supplemental  table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2017/08/29	rogid:dK5TqSajxrGKjiNwRjeZCV519XE10090	rogid:qRXsrB2fLT1DMVIVRWKFYe4Aln49606	intact-crc:CF2108B52D4E653D|rigid:Y1TB380D/8n7jYy0R708j8QSP/U	false	green fluorescent protein tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9EQH3	uniprotkb:Q92609	intact:EBI-775825|uniprotkb:Q61123|ensembl:ENSMUSP00000034131	intact:EBI-742381|uniprotkb:A6NP25|intact:EBI-28978959|ensembl:ENSP00000253692|ensembl:ENSP00000398127|uniprotkb:C9JP52	psi-mi:vps35_mouse(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:Vps35(gene name)|psi-mi:Vps35(display_short)|uniprotkb:Mem3(gene name synonym)	psi-mi:tbcd5_human(display_long)|uniprotkb:TBC1D5(gene name)|psi-mi:TBC1D5(display_short)|uniprotkb:KIAA0210(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846643|imex:IM-26126-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_075373.1|dip:DIP-32210N|ensembl:ENSMUSG00000031696(gene)|ensembl:ENSMUST00000034131(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006624"(vacuolar protein processing)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007416"(synapse assembly)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032463"(negative regulation of protein homooligomerization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090326"(positive regulation of locomotion involved in locomotory behavior)|go:"GO:0097422"(tubular endosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903181"(positive regulation of dopamine biosynthetic process)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903828"(negative regulation of protein localization)|go:"GO:1905166"(negative regulation of lysosomal protein catabolic process)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|mint:Q9EQH3|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698	ensembl:ENSP00000253692|ensembl:ENSP00000398127|ensembl:ENSP00000402935|ensembl:ENST00000446818|refseq:NP_055559.1|refseq:XP_011532586.1|refseq:XP_011532583.1|refseq:XP_011532585.1|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006914"(autophagy)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0035612"(AP-2 adaptor complex binding)|ensembl:ENSG00000131374(gene)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042594"(response to starvation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1905394"(retromer complex binding)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|mint:Q92609|rcsb pdb:5GTU|ensembl:ENST00000253692(transcript)|ensembl:ENST00000429383(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|refseq:NP_001127853.1|refseq:XP_006713493.1|refseq:XP_016863041.1|refseq:XP_016863042.1|refseq:XP_016863043.1|refseq:XP_016863044.1|refseq:XP_016863045.1|refseq:XP_016863046.1	-	-	-	figure legend:5C, supplemental  table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2017/08/29	rogid:dK5TqSajxrGKjiNwRjeZCV519XE10090	rogid:GZ7WP4suMiSPSAJK0TZWQMQZxzU9606	intact-crc:CF2108B52D4E653D|rigid:Y1TB380D/8n7jYy0R708j8QSP/U	false	green fluorescent protein tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9EQH3	uniprotkb:Q2M389	intact:EBI-775825|uniprotkb:Q61123|ensembl:ENSMUSP00000034131	intact:EBI-2563783|uniprotkb:Q8IW61|uniprotkb:Q9NVD6|uniprotkb:Q8N5W7|uniprotkb:Q2NL83|uniprotkb:Q9UPW7|ensembl:ENSP00000328062	psi-mi:vps35_mouse(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:Vps35(gene name)|psi-mi:Vps35(display_short)|uniprotkb:Mem3(gene name synonym)	psi-mi:wasc4_human(display_long)|uniprotkb:WASHC4(gene name)|psi-mi:WASHC4(display_short)|uniprotkb:KIAA1033(gene name synonym)|uniprotkb:Strumpellin and WASH-interacting protein(gene name synonym)|uniprotkb:WASH complex subunit SWIP(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846643|imex:IM-26126-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_075373.1|dip:DIP-32210N|ensembl:ENSMUSG00000031696(gene)|ensembl:ENSMUST00000034131(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006624"(vacuolar protein processing)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007416"(synapse assembly)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032463"(negative regulation of protein homooligomerization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090326"(positive regulation of locomotion involved in locomotory behavior)|go:"GO:0097422"(tubular endosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903181"(positive regulation of dopamine biosynthetic process)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903828"(negative regulation of protein localization)|go:"GO:1905166"(negative regulation of lysosomal protein catabolic process)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|mint:Q9EQH3|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698	refseq:NP_056090.1|ensembl:ENSG00000136051(gene)|ensembl:ENST00000332180(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0007032"(endosome organization)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0071203"(WASH complex)|go:"GO:0140591"(nuclear envelope budding)|interpro:IPR027307|interpro:IPR028191|interpro:IPR028283|interpro:IPR028282|refseq:NP_001280569.1	-	-	-	figure legend:5C, supplemental  table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2017/08/29	rogid:dK5TqSajxrGKjiNwRjeZCV519XE10090	rogid:APnP9mxAqwzKEoQFGt94Z8Y73t49606	intact-crc:CF2108B52D4E653D|rigid:Y1TB380D/8n7jYy0R708j8QSP/U	false	green fluorescent protein tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9EQH3	uniprotkb:P52907	intact:EBI-775825|uniprotkb:Q61123|ensembl:ENSMUSP00000034131	intact:EBI-355586|uniprotkb:Q53FQ6|uniprotkb:Q6FHD5|ensembl:ENSP00000263168	psi-mi:vps35_mouse(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:Vps35(gene name)|psi-mi:Vps35(display_short)|uniprotkb:Mem3(gene name synonym)	psi-mi:caza1_human(display_long)|uniprotkb:CAPZA1(gene name)|psi-mi:CAPZA1(display_short)|uniprotkb:CapZ alpha-1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846643|imex:IM-26126-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_075373.1|dip:DIP-32210N|ensembl:ENSMUSG00000031696(gene)|ensembl:ENSMUST00000034131(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006624"(vacuolar protein processing)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007416"(synapse assembly)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032463"(negative regulation of protein homooligomerization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090326"(positive regulation of locomotion involved in locomotory behavior)|go:"GO:0097422"(tubular endosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903181"(positive regulation of dopamine biosynthetic process)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903828"(negative regulation of protein localization)|go:"GO:1905166"(negative regulation of lysosomal protein catabolic process)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|mint:Q9EQH3|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698	refseq:NP_006126.1|ensembl:ENSG00000116489(gene)|ensembl:ENST00000263168(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0034329"(cell junction assembly)|go:"GO:0045296"(cadherin binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071203"(WASH complex)|interpro:IPR002189(F-actin capping protein, alpha subunit)|interpro:IPR017865|interpro:IPR037282|interpro:IPR042276|interpro:IPR042489|mint:P52907|rcsb pdb:1MQ1|rcsb pdb:1MWN|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-879415|reactome:R-HSA-8950505|reactome:R-HSA-9662360|reactome:R-HSA-983231	-	-	-	figure legend:5C, supplemental  table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2017/08/29	rogid:dK5TqSajxrGKjiNwRjeZCV519XE10090	rogid:97S4WPtjgt4MDLoptRhQ2yH8UNE9606	intact-crc:CF2108B52D4E653D|rigid:Y1TB380D/8n7jYy0R708j8QSP/U	false	green fluorescent protein tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9EQH3	uniprotkb:Q5T1M5	intact:EBI-775825|uniprotkb:Q61123|ensembl:ENSMUSP00000034131	intact:EBI-5235934|uniprotkb:Q05DK8|uniprotkb:Q5T1M2|uniprotkb:Q6DD85|uniprotkb:Q9Y4D0|ensembl:ENSP00000238256|ensembl:ENSP00000416158	psi-mi:vps35_mouse(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:Vps35(gene name)|psi-mi:Vps35(display_short)|uniprotkb:Mem3(gene name synonym)	psi-mi:fkb15_human(display_long)|uniprotkb:FKBP15(gene name)|psi-mi:FKBP15(display_short)|uniprotkb:KIAA0674(gene name synonym)|uniprotkb:133 kDa FK506-binding protein(gene name synonym)|uniprotkb:WASP- and FKBP-like protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846643|imex:IM-26126-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_075373.1|dip:DIP-32210N|ensembl:ENSMUSG00000031696(gene)|ensembl:ENSMUST00000034131(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006624"(vacuolar protein processing)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007416"(synapse assembly)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032463"(negative regulation of protein homooligomerization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090326"(positive regulation of locomotion involved in locomotory behavior)|go:"GO:0097422"(tubular endosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903181"(positive regulation of dopamine biosynthetic process)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903828"(negative regulation of protein localization)|go:"GO:1905166"(negative regulation of lysosomal protein catabolic process)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|mint:Q9EQH3|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698	refseq:NP_056073.1|refseq:XP_006717081.1|ensembl:ENSG00000119321(gene)|ensembl:ENST00000238256(transcript)|ensembl:ENST00000446284(transcript)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0003779"(actin binding)|go:"GO:0005769"(early endosome)|go:"GO:0006897"(endocytosis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030426"(growth cone)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|mint:Q5T1M5	-	-	-	figure legend:5C, supplemental  table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2017/08/29	rogid:dK5TqSajxrGKjiNwRjeZCV519XE10090	rogid:2th35ZHTzidVTyWGpc0Emz3foIY9606	intact-crc:CF2108B52D4E653D|rigid:Y1TB380D/8n7jYy0R708j8QSP/U	false	green fluorescent protein tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9EQH3	uniprotkb:Q12768	intact:EBI-775825|uniprotkb:Q61123|ensembl:ENSMUSP00000034131	intact:EBI-2563794|uniprotkb:A8K4R7|uniprotkb:Q3KQX5|uniprotkb:Q8TBQ2|ensembl:ENSP00000318016	psi-mi:vps35_mouse(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:Vps35(gene name)|psi-mi:Vps35(display_short)|uniprotkb:Mem3(gene name synonym)	psi-mi:wasc5_human(display_long)|uniprotkb:WASHC5(gene name)|psi-mi:WASHC5(display_short)|uniprotkb:KIAA0196(gene name synonym)|uniprotkb:Strumpellin(gene name synonym)|uniprotkb:WASH complex subunit strumpellin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846643|imex:IM-26126-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_075373.1|dip:DIP-32210N|ensembl:ENSMUSG00000031696(gene)|ensembl:ENSMUST00000034131(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006624"(vacuolar protein processing)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007416"(synapse assembly)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032463"(negative regulation of protein homooligomerization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090326"(positive regulation of locomotion involved in locomotory behavior)|go:"GO:0097422"(tubular endosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903181"(positive regulation of dopamine biosynthetic process)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903828"(negative regulation of protein localization)|go:"GO:1905166"(negative regulation of lysosomal protein catabolic process)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|mint:Q9EQH3|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698	refseq:NP_055661.3|ensembl:ENSG00000164961(gene)|ensembl:ENST00000318410(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0034629"|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051125"(regulation of actin nucleation)|go:"GO:0071203"(WASH complex)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0097494"(regulation of vesicle size)|go:"GO:0140285"(endosome fission)|interpro:IPR019393|mint:Q12768|refseq:XP_016869602.1	-	-	-	figure legend:5C, supplemental  table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2017/08/29	rogid:dK5TqSajxrGKjiNwRjeZCV519XE10090	rogid:9QEw0Z7NIOvpVJtWXcLp67ApJdk9606	intact-crc:CF2108B52D4E653D|rigid:Y1TB380D/8n7jYy0R708j8QSP/U	false	green fluorescent protein tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9EQH3	uniprotkb:Q4G0F5	intact:EBI-775825|uniprotkb:Q61123|ensembl:ENSMUSP00000034131	intact:EBI-6151831|uniprotkb:Q96A55|ensembl:ENSP00000281187|ensembl:ENSP00000434162	psi-mi:vps35_mouse(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:Vps35(gene name)|psi-mi:Vps35(display_short)|uniprotkb:Mem3(gene name synonym)	psi-mi:vp26b_human(display_long)|uniprotkb:Vesicle protein sorting 26B(gene name synonym)|uniprotkb:VPS26B(gene name)|psi-mi:VPS26B(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846643|imex:IM-26126-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_075373.1|dip:DIP-32210N|ensembl:ENSMUSG00000031696(gene)|ensembl:ENSMUST00000034131(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006624"(vacuolar protein processing)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007416"(synapse assembly)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032463"(negative regulation of protein homooligomerization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090326"(positive regulation of locomotion involved in locomotory behavior)|go:"GO:0097422"(tubular endosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903181"(positive regulation of dopamine biosynthetic process)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903828"(negative regulation of protein localization)|go:"GO:1905166"(negative regulation of lysosomal protein catabolic process)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|mint:Q9EQH3|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698	refseq:NP_443107.1|ensembl:ENSG00000151502(gene)|ensembl:ENST00000281187(transcript)|ensembl:ENST00000525095(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR028934	-	-	-	figure legend:5C, supplemental  table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2017/08/29	rogid:dK5TqSajxrGKjiNwRjeZCV519XE10090	rogid:8NQBMiFKQXjWM4/Vy7swv2pW0V89606	intact-crc:CF2108B52D4E653D|rigid:Y1TB380D/8n7jYy0R708j8QSP/U	false	green fluorescent protein tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9QZ88	uniprotkb:Q9EQH3	intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020	intact:EBI-775825|uniprotkb:Q61123|ensembl:ENSMUSP00000034131	psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym)	psi-mi:vps35_mouse(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:Vps35(gene name)|psi-mi:Vps35(display_short)|uniprotkb:Mem3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9845900|imex:IM-26126-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome)	refseq:NP_075373.1|dip:DIP-32210N|ensembl:ENSMUSG00000031696(gene)|ensembl:ENSMUST00000034131(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006624"(vacuolar protein processing)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007416"(synapse assembly)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032463"(negative regulation of protein homooligomerization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090326"(positive regulation of locomotion involved in locomotory behavior)|go:"GO:0097422"(tubular endosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903181"(positive regulation of dopamine biosynthetic process)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903828"(negative regulation of protein localization)|go:"GO:1905166"(negative regulation of lysosomal protein catabolic process)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|mint:Q9EQH3|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698	-	function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint	-	figure legend:3B|comment:A VPS29 leu152glu mutation does not change the association.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2014/10/14	2014/10/16	rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090	rogid:dK5TqSajxrGKjiNwRjeZCV519XE10090	intact-crc:3696C21CCC1D5148|rigid:lGRCARmn5gKpto8ctseoR9xMkh0	false	mutation with no effect:152-152	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9QZ88	uniprotkb:Q92609	intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020	intact:EBI-742381|uniprotkb:A6NP25|intact:EBI-28978959|ensembl:ENSP00000253692|ensembl:ENSP00000398127|uniprotkb:C9JP52	psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym)	psi-mi:tbcd5_human(display_long)|uniprotkb:TBC1D5(gene name)|psi-mi:TBC1D5(display_short)|uniprotkb:KIAA0210(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9845883|imex:IM-26126-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome)	ensembl:ENSP00000253692|ensembl:ENSP00000398127|ensembl:ENSP00000402935|ensembl:ENST00000446818|refseq:NP_055559.1|refseq:XP_011532586.1|refseq:XP_011532583.1|refseq:XP_011532585.1|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006914"(autophagy)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0035612"(AP-2 adaptor complex binding)|ensembl:ENSG00000131374(gene)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042594"(response to starvation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1905394"(retromer complex binding)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|mint:Q92609|rcsb pdb:5GTU|ensembl:ENST00000253692(transcript)|ensembl:ENST00000429383(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|refseq:NP_001127853.1|refseq:XP_006713493.1|refseq:XP_016863041.1|refseq:XP_016863042.1|refseq:XP_016863043.1|refseq:XP_016863044.1|refseq:XP_016863045.1|refseq:XP_016863046.1	-	function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint	-	figure legend:3A and B, S2A, Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2014/10/14	2015/12/11	rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090	rogid:GZ7WP4suMiSPSAJK0TZWQMQZxzU9606	intact-crc:C286B69E762A7421|rigid:r1gUYAmjVdSMX/uBE88h5A0omZA	false	mutation disrupting interaction strength:152-152	sufficient binding region:50-674	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9QZ88	uniprotkb:Q9QZ88	intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020	intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020	psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym)	psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846915|imex:IM-26126-33	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome)	refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome)	-	function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint	function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint	figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2014/10/14	2017/08/17	rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090	rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090	intact-crc:79E5784FB7D07F9A|rigid:gJwXokXxPJPn0A6kfTcF5fLFQxE	false	-	-	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y4E1	uniprotkb:Q9EQH3	intact:EBI-948957|intact:EBI-28970026|ensembl:ENSP00000363482|uniprotkb:Q5SQU4|uniprotkb:Q5SQU5|uniprotkb:Q7L521|uniprotkb:Q9UG79|intact:EBI-2563814|uniprotkb:B4DZQ6|uniprotkb:B9EK53|uniprotkb:F5H0J6|uniprotkb:F5H871	intact:EBI-775825|uniprotkb:Q61123|ensembl:ENSMUSP00000034131	psi-mi:wac2c_human(display_long)|uniprotkb:VPEF(gene name synonym)|uniprotkb:WASHC2C(gene name)|psi-mi:WASHC2C(display_short)|uniprotkb:FAM21C(gene name synonym)|uniprotkb:KIAA0592(gene name synonym)|uniprotkb:Vaccinia virus penetration factor(gene name synonym)	psi-mi:vps35_mouse(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:Vps35(gene name)|psi-mi:Vps35(display_short)|uniprotkb:Mem3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846919|imex:IM-26126-35	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000172661(gene)|ensembl:ENST00000374362(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0015031"(protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032456"(endocytic recycling)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0071203"(WASH complex)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1900024"(regulation of substrate adhesion-dependent cell spreading)|go:"GO:1905394"(retromer complex binding)|go:"GO:2000813"(negative regulation of barbed-end actin filament capping)|interpro:IPR029341|mint:Q9Y4E1|ensembl:ENST00000540872|ensembl:ENSP00000439811|ensembl:ENSP00000363482|ensembl:ENST00000537517|ensembl:ENSP00000442128|refseq:NP_001162577.1|refseq:NP_001162578.1|refseq:NP_056077.2	refseq:NP_075373.1|dip:DIP-32210N|ensembl:ENSMUSG00000031696(gene)|ensembl:ENSMUST00000034131(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006624"(vacuolar protein processing)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007416"(synapse assembly)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032463"(negative regulation of protein homooligomerization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090326"(positive regulation of locomotion involved in locomotory behavior)|go:"GO:0097422"(tubular endosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903181"(positive regulation of dopamine biosynthetic process)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903828"(negative regulation of protein localization)|go:"GO:1905166"(negative regulation of lysosomal protein catabolic process)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|mint:Q9EQH3|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698	-	-	-	figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2014/10/14	2018/09/18	rogid:gUK2aPVIQiHey/Wka1mgFuBTKNE9606	rogid:dK5TqSajxrGKjiNwRjeZCV519XE10090	intact-crc:DFA015BC7CE087E9|rigid:T53PmDqKoRH7KZyKuNd7EwfT70M	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q5T1M5	uniprotkb:Q5T1M5	intact:EBI-5235934|uniprotkb:Q05DK8|uniprotkb:Q5T1M2|uniprotkb:Q6DD85|uniprotkb:Q9Y4D0|ensembl:ENSP00000238256|ensembl:ENSP00000416158	intact:EBI-5235934|uniprotkb:Q05DK8|uniprotkb:Q5T1M2|uniprotkb:Q6DD85|uniprotkb:Q9Y4D0|ensembl:ENSP00000238256|ensembl:ENSP00000416158	psi-mi:fkb15_human(display_long)|uniprotkb:FKBP15(gene name)|psi-mi:FKBP15(display_short)|uniprotkb:KIAA0674(gene name synonym)|uniprotkb:133 kDa FK506-binding protein(gene name synonym)|uniprotkb:WASP- and FKBP-like protein(gene name synonym)	psi-mi:fkb15_human(display_long)|uniprotkb:FKBP15(gene name)|psi-mi:FKBP15(display_short)|uniprotkb:KIAA0674(gene name synonym)|uniprotkb:133 kDa FK506-binding protein(gene name synonym)|uniprotkb:WASP- and FKBP-like protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846981|imex:IM-26126-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056073.1|refseq:XP_006717081.1|ensembl:ENSG00000119321(gene)|ensembl:ENST00000238256(transcript)|ensembl:ENST00000446284(transcript)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0003779"(actin binding)|go:"GO:0005769"(early endosome)|go:"GO:0006897"(endocytosis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030426"(growth cone)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|mint:Q5T1M5	refseq:NP_056073.1|refseq:XP_006717081.1|ensembl:ENSG00000119321(gene)|ensembl:ENST00000238256(transcript)|ensembl:ENST00000446284(transcript)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0003779"(actin binding)|go:"GO:0005769"(early endosome)|go:"GO:0006897"(endocytosis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030426"(growth cone)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|mint:Q5T1M5	-	-	-	figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2014/10/14	2015/12/11	rogid:2th35ZHTzidVTyWGpc0Emz3foIY9606	rogid:2th35ZHTzidVTyWGpc0Emz3foIY9606	intact-crc:4D99FF1725874921|rigid:rYsbUU+idr3qmqnfCO2dMoSCkO0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y4E1	uniprotkb:Q5T1M5	intact:EBI-948957|intact:EBI-28970026|ensembl:ENSP00000363482|uniprotkb:Q5SQU4|uniprotkb:Q5SQU5|uniprotkb:Q7L521|uniprotkb:Q9UG79|intact:EBI-2563814|uniprotkb:B4DZQ6|uniprotkb:B9EK53|uniprotkb:F5H0J6|uniprotkb:F5H871	intact:EBI-5235934|uniprotkb:Q05DK8|uniprotkb:Q5T1M2|uniprotkb:Q6DD85|uniprotkb:Q9Y4D0|ensembl:ENSP00000238256|ensembl:ENSP00000416158	psi-mi:wac2c_human(display_long)|uniprotkb:VPEF(gene name synonym)|uniprotkb:WASHC2C(gene name)|psi-mi:WASHC2C(display_short)|uniprotkb:FAM21C(gene name synonym)|uniprotkb:KIAA0592(gene name synonym)|uniprotkb:Vaccinia virus penetration factor(gene name synonym)	psi-mi:fkb15_human(display_long)|uniprotkb:FKBP15(gene name)|psi-mi:FKBP15(display_short)|uniprotkb:KIAA0674(gene name synonym)|uniprotkb:133 kDa FK506-binding protein(gene name synonym)|uniprotkb:WASP- and FKBP-like protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846977|imex:IM-26126-53	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000172661(gene)|ensembl:ENST00000374362(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0015031"(protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032456"(endocytic recycling)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0071203"(WASH complex)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1900024"(regulation of substrate adhesion-dependent cell spreading)|go:"GO:1905394"(retromer complex binding)|go:"GO:2000813"(negative regulation of barbed-end actin filament capping)|interpro:IPR029341|mint:Q9Y4E1|ensembl:ENST00000540872|ensembl:ENSP00000439811|ensembl:ENSP00000363482|ensembl:ENST00000537517|ensembl:ENSP00000442128|refseq:NP_001162577.1|refseq:NP_001162578.1|refseq:NP_056077.2	refseq:NP_056073.1|refseq:XP_006717081.1|ensembl:ENSG00000119321(gene)|ensembl:ENST00000238256(transcript)|ensembl:ENST00000446284(transcript)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0003779"(actin binding)|go:"GO:0005769"(early endosome)|go:"GO:0006897"(endocytosis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030426"(growth cone)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|mint:Q5T1M5	-	-	-	figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2014/10/14	2018/09/18	rogid:gUK2aPVIQiHey/Wka1mgFuBTKNE9606	rogid:2th35ZHTzidVTyWGpc0Emz3foIY9606	intact-crc:0CB58C94FC46DC9B|rigid:nZ8kQDGWz2TFsSxKLP0D9/rJXf0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q5T1M5	uniprotkb:Q9EQH3	intact:EBI-5235934|uniprotkb:Q05DK8|uniprotkb:Q5T1M2|uniprotkb:Q6DD85|uniprotkb:Q9Y4D0|ensembl:ENSP00000238256|ensembl:ENSP00000416158	intact:EBI-775825|uniprotkb:Q61123|ensembl:ENSMUSP00000034131	psi-mi:fkb15_human(display_long)|uniprotkb:FKBP15(gene name)|psi-mi:FKBP15(display_short)|uniprotkb:KIAA0674(gene name synonym)|uniprotkb:133 kDa FK506-binding protein(gene name synonym)|uniprotkb:WASP- and FKBP-like protein(gene name synonym)	psi-mi:vps35_mouse(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:Vps35(gene name)|psi-mi:Vps35(display_short)|uniprotkb:Mem3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846973|imex:IM-26126-51	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056073.1|refseq:XP_006717081.1|ensembl:ENSG00000119321(gene)|ensembl:ENST00000238256(transcript)|ensembl:ENST00000446284(transcript)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0003779"(actin binding)|go:"GO:0005769"(early endosome)|go:"GO:0006897"(endocytosis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030426"(growth cone)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|mint:Q5T1M5	refseq:NP_075373.1|dip:DIP-32210N|ensembl:ENSMUSG00000031696(gene)|ensembl:ENSMUST00000034131(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006624"(vacuolar protein processing)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007416"(synapse assembly)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032463"(negative regulation of protein homooligomerization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090326"(positive regulation of locomotion involved in locomotory behavior)|go:"GO:0097422"(tubular endosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903181"(positive regulation of dopamine biosynthetic process)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903828"(negative regulation of protein localization)|go:"GO:1905166"(negative regulation of lysosomal protein catabolic process)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|mint:Q9EQH3|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698	-	-	-	figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2014/10/14	2015/12/11	rogid:2th35ZHTzidVTyWGpc0Emz3foIY9606	rogid:dK5TqSajxrGKjiNwRjeZCV519XE10090	intact-crc:F5B9A8A28B9B7618|rigid:H2/M55b3hBldVinD5pHPJC+6Xxc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9EQH3	uniprotkb:Q5T1M5	intact:EBI-775825|uniprotkb:Q61123|ensembl:ENSMUSP00000034131	intact:EBI-5235934|uniprotkb:Q05DK8|uniprotkb:Q5T1M2|uniprotkb:Q6DD85|uniprotkb:Q9Y4D0|ensembl:ENSP00000238256|ensembl:ENSP00000416158	psi-mi:vps35_mouse(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:Vps35(gene name)|psi-mi:Vps35(display_short)|uniprotkb:Mem3(gene name synonym)	psi-mi:fkb15_human(display_long)|uniprotkb:FKBP15(gene name)|psi-mi:FKBP15(display_short)|uniprotkb:KIAA0674(gene name synonym)|uniprotkb:133 kDa FK506-binding protein(gene name synonym)|uniprotkb:WASP- and FKBP-like protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846932|imex:IM-26126-37	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_075373.1|dip:DIP-32210N|ensembl:ENSMUSG00000031696(gene)|ensembl:ENSMUST00000034131(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006624"(vacuolar protein processing)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007416"(synapse assembly)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032463"(negative regulation of protein homooligomerization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090326"(positive regulation of locomotion involved in locomotory behavior)|go:"GO:0097422"(tubular endosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903181"(positive regulation of dopamine biosynthetic process)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903828"(negative regulation of protein localization)|go:"GO:1905166"(negative regulation of lysosomal protein catabolic process)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|mint:Q9EQH3|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698	refseq:NP_056073.1|refseq:XP_006717081.1|ensembl:ENSG00000119321(gene)|ensembl:ENST00000238256(transcript)|ensembl:ENST00000446284(transcript)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0003779"(actin binding)|go:"GO:0005769"(early endosome)|go:"GO:0006897"(endocytosis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030426"(growth cone)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|mint:Q5T1M5	-	-	-	figure legend:Table 2 and 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2014/10/14	2015/12/11	rogid:dK5TqSajxrGKjiNwRjeZCV519XE10090	rogid:2th35ZHTzidVTyWGpc0Emz3foIY9606	intact-crc:05B40E04A82EEEB7|rigid:H2/M55b3hBldVinD5pHPJC+6Xxc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9QZ88	uniprotkb:Q5T1M5	intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020	intact:EBI-5235934|uniprotkb:Q05DK8|uniprotkb:Q5T1M2|uniprotkb:Q6DD85|uniprotkb:Q9Y4D0|ensembl:ENSP00000238256|ensembl:ENSP00000416158	psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym)	psi-mi:fkb15_human(display_long)|uniprotkb:FKBP15(gene name)|psi-mi:FKBP15(display_short)|uniprotkb:KIAA0674(gene name synonym)|uniprotkb:133 kDa FK506-binding protein(gene name synonym)|uniprotkb:WASP- and FKBP-like protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846969|imex:IM-26126-49	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome)	refseq:NP_056073.1|refseq:XP_006717081.1|ensembl:ENSG00000119321(gene)|ensembl:ENST00000238256(transcript)|ensembl:ENST00000446284(transcript)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0003779"(actin binding)|go:"GO:0005769"(early endosome)|go:"GO:0006897"(endocytosis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030426"(growth cone)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|mint:Q5T1M5	-	function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint	-	figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2014/10/14	2014/10/16	rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090	rogid:2th35ZHTzidVTyWGpc0Emz3foIY9606	intact-crc:AAF0E167377624E8|rigid:Hl51dH1OI9o/J8ADveMqcOwhO6U	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96QK1	uniprotkb:Q92609	intact:EBI-1054634|uniprotkb:Q561W2|uniprotkb:Q9H016|uniprotkb:Q9H096|uniprotkb:Q9H4P3|uniprotkb:Q9H8J0|uniprotkb:Q9NRS7|uniprotkb:Q9NVG2|uniprotkb:Q9NX80|uniprotkb:Q9NZK2|ensembl:ENSP00000299138	intact:EBI-742381|uniprotkb:A6NP25|intact:EBI-28978959|ensembl:ENSP00000253692|ensembl:ENSP00000398127|uniprotkb:C9JP52	psi-mi:vps35_human(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:VPS35(gene name)|psi-mi:VPS35(display_short)|uniprotkb:MEM3(gene name synonym)|uniprotkb:TCCCTA00141(orf name)	psi-mi:tbcd5_human(display_long)|uniprotkb:TBC1D5(gene name)|psi-mi:TBC1D5(display_short)|uniprotkb:KIAA0210(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9845924|imex:IM-26126-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060676.2|rcsb pdb:5F0J|rcsb pdb:5F0K|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|rcsb pdb:5OSH|rcsb pdb:5OSI|rcsb pdb:7BLN|rcsb pdb:7BLO|reactome:R-HSA-3238698|ensembl:ENSG00000069329(gene)|ensembl:ENST00000299138(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0097422"(tubular endosome)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|rcsb pdb:2R17|dip:DIP-29076N	ensembl:ENSP00000253692|ensembl:ENSP00000398127|ensembl:ENSP00000402935|ensembl:ENST00000446818|refseq:NP_055559.1|refseq:XP_011532586.1|refseq:XP_011532583.1|refseq:XP_011532585.1|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006914"(autophagy)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0035612"(AP-2 adaptor complex binding)|ensembl:ENSG00000131374(gene)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042594"(response to starvation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1905394"(retromer complex binding)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|mint:Q92609|rcsb pdb:5GTU|ensembl:ENST00000253692(transcript)|ensembl:ENST00000429383(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|refseq:NP_001127853.1|refseq:XP_006713493.1|refseq:XP_016863041.1|refseq:XP_016863042.1|refseq:XP_016863043.1|refseq:XP_016863044.1|refseq:XP_016863045.1|refseq:XP_016863046.1	-	-	comment:TBC1D5 mutant constructs R169A, Q204A, R169A, Q204A and SST43AAA also showed association	comment:weak interaction|figure legend:3C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2017/08/14	rogid:EXkMduDQKNCdp876vGF5vna9t389606	rogid:GZ7WP4suMiSPSAJK0TZWQMQZxzU9606	intact-crc:01E392D5CECEBCEA|rigid:TRLOvWuSUMsdRR3nwoprSjf3gns	false	-	green fluorescent protein tag:?-?|sufficient binding region:1-548	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9EQH3	uniprotkb:Q96QK1	intact:EBI-775825|uniprotkb:Q61123|ensembl:ENSMUSP00000034131	intact:EBI-1054634|uniprotkb:Q561W2|uniprotkb:Q9H016|uniprotkb:Q9H096|uniprotkb:Q9H4P3|uniprotkb:Q9H8J0|uniprotkb:Q9NRS7|uniprotkb:Q9NVG2|uniprotkb:Q9NX80|uniprotkb:Q9NZK2|ensembl:ENSP00000299138	psi-mi:vps35_mouse(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:Vps35(gene name)|psi-mi:Vps35(display_short)|uniprotkb:Mem3(gene name synonym)	psi-mi:vps35_human(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:VPS35(gene name)|psi-mi:VPS35(display_short)|uniprotkb:MEM3(gene name synonym)|uniprotkb:TCCCTA00141(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846150|imex:IM-26126-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_075373.1|dip:DIP-32210N|ensembl:ENSMUSG00000031696(gene)|ensembl:ENSMUST00000034131(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006624"(vacuolar protein processing)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007416"(synapse assembly)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032463"(negative regulation of protein homooligomerization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090326"(positive regulation of locomotion involved in locomotory behavior)|go:"GO:0097422"(tubular endosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903181"(positive regulation of dopamine biosynthetic process)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903828"(negative regulation of protein localization)|go:"GO:1905166"(negative regulation of lysosomal protein catabolic process)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|mint:Q9EQH3|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698	refseq:NP_060676.2|rcsb pdb:5F0J|rcsb pdb:5F0K|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|rcsb pdb:5OSH|rcsb pdb:5OSI|rcsb pdb:7BLN|rcsb pdb:7BLO|reactome:R-HSA-3238698|ensembl:ENSG00000069329(gene)|ensembl:ENST00000299138(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0097422"(tubular endosome)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|rcsb pdb:2R17|dip:DIP-29076N	-	-	-	comment:VPS26A and/or VPS26B was also detected|figure legend:5B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2017/08/17	rogid:dK5TqSajxrGKjiNwRjeZCV519XE10090	rogid:EXkMduDQKNCdp876vGF5vna9t389606	intact-crc:7054BE894E237CBC|rigid:TOvA9I+CAqBiM8ZTnP3qGQKTp/c	false	green fluorescent protein tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9EQH3	uniprotkb:A8K0Z3	intact:EBI-775825|uniprotkb:Q61123|ensembl:ENSMUSP00000034131	intact:EBI-6160405|intact:EBI-28977476|ensembl:ENSP00000485627	psi-mi:vps35_mouse(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:Vps35(gene name)|psi-mi:Vps35(display_short)|uniprotkb:Mem3(gene name synonym)	psi-mi:wash1_human(display_long)|uniprotkb:WASHC1(gene name)|psi-mi:WASHC1(display_short)|uniprotkb:CXYorf1-like protein on chromosome 9(gene name synonym)|uniprotkb:FAM39E(gene name synonym)|uniprotkb:Protein FAM39E(gene name synonym)|uniprotkb:WAS protein family homolog 1(gene name synonym)|uniprotkb:WASH1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846150|imex:IM-26126-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_075373.1|dip:DIP-32210N|ensembl:ENSMUSG00000031696(gene)|ensembl:ENSMUST00000034131(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006624"(vacuolar protein processing)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007416"(synapse assembly)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032463"(negative regulation of protein homooligomerization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090326"(positive regulation of locomotion involved in locomotory behavior)|go:"GO:0097422"(tubular endosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903181"(positive regulation of dopamine biosynthetic process)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903828"(negative regulation of protein localization)|go:"GO:1905166"(negative regulation of lysosomal protein catabolic process)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|mint:Q9EQH3|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698	ensembl:ENSP00000485627|refseq:NP_878908.4|ensembl:ENSG00000181404(gene)|ensembl:ENST00000442898(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031274"(positive regulation of pseudopodium assembly)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043553"(negative regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071203"(WASH complex)|interpro:IPR021854|interpro:IPR028290	-	-	-	comment:VPS26A and/or VPS26B was also detected|figure legend:5B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2017/08/17	rogid:dK5TqSajxrGKjiNwRjeZCV519XE10090	rogid:X7zdUL7YK2B6tU4RUdSTXrJfXLk9606	intact-crc:7054BE894E237CBC|rigid:TOvA9I+CAqBiM8ZTnP3qGQKTp/c	false	green fluorescent protein tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9EQH3	uniprotkb:Q92609	intact:EBI-775825|uniprotkb:Q61123|ensembl:ENSMUSP00000034131	intact:EBI-742381|uniprotkb:A6NP25|intact:EBI-28978959|ensembl:ENSP00000253692|ensembl:ENSP00000398127|uniprotkb:C9JP52	psi-mi:vps35_mouse(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:Vps35(gene name)|psi-mi:Vps35(display_short)|uniprotkb:Mem3(gene name synonym)	psi-mi:tbcd5_human(display_long)|uniprotkb:TBC1D5(gene name)|psi-mi:TBC1D5(display_short)|uniprotkb:KIAA0210(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846150|imex:IM-26126-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_075373.1|dip:DIP-32210N|ensembl:ENSMUSG00000031696(gene)|ensembl:ENSMUST00000034131(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006624"(vacuolar protein processing)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007416"(synapse assembly)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032463"(negative regulation of protein homooligomerization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090326"(positive regulation of locomotion involved in locomotory behavior)|go:"GO:0097422"(tubular endosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903181"(positive regulation of dopamine biosynthetic process)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903828"(negative regulation of protein localization)|go:"GO:1905166"(negative regulation of lysosomal protein catabolic process)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|mint:Q9EQH3|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698	ensembl:ENSP00000253692|ensembl:ENSP00000398127|ensembl:ENSP00000402935|ensembl:ENST00000446818|refseq:NP_055559.1|refseq:XP_011532586.1|refseq:XP_011532583.1|refseq:XP_011532585.1|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006914"(autophagy)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0035612"(AP-2 adaptor complex binding)|ensembl:ENSG00000131374(gene)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042594"(response to starvation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1905394"(retromer complex binding)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|mint:Q92609|rcsb pdb:5GTU|ensembl:ENST00000253692(transcript)|ensembl:ENST00000429383(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|refseq:NP_001127853.1|refseq:XP_006713493.1|refseq:XP_016863041.1|refseq:XP_016863042.1|refseq:XP_016863043.1|refseq:XP_016863044.1|refseq:XP_016863045.1|refseq:XP_016863046.1	-	-	-	comment:VPS26A and/or VPS26B was also detected|figure legend:5B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2017/08/17	rogid:dK5TqSajxrGKjiNwRjeZCV519XE10090	rogid:GZ7WP4suMiSPSAJK0TZWQMQZxzU9606	intact-crc:7054BE894E237CBC|rigid:TOvA9I+CAqBiM8ZTnP3qGQKTp/c	false	green fluorescent protein tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9EQH3	uniprotkb:Q12768	intact:EBI-775825|uniprotkb:Q61123|ensembl:ENSMUSP00000034131	intact:EBI-2563794|uniprotkb:A8K4R7|uniprotkb:Q3KQX5|uniprotkb:Q8TBQ2|ensembl:ENSP00000318016	psi-mi:vps35_mouse(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:Vps35(gene name)|psi-mi:Vps35(display_short)|uniprotkb:Mem3(gene name synonym)	psi-mi:wasc5_human(display_long)|uniprotkb:WASHC5(gene name)|psi-mi:WASHC5(display_short)|uniprotkb:KIAA0196(gene name synonym)|uniprotkb:Strumpellin(gene name synonym)|uniprotkb:WASH complex subunit strumpellin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846150|imex:IM-26126-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_075373.1|dip:DIP-32210N|ensembl:ENSMUSG00000031696(gene)|ensembl:ENSMUST00000034131(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006624"(vacuolar protein processing)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007416"(synapse assembly)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032463"(negative regulation of protein homooligomerization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090326"(positive regulation of locomotion involved in locomotory behavior)|go:"GO:0097422"(tubular endosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903181"(positive regulation of dopamine biosynthetic process)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903828"(negative regulation of protein localization)|go:"GO:1905166"(negative regulation of lysosomal protein catabolic process)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|mint:Q9EQH3|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698	refseq:NP_055661.3|ensembl:ENSG00000164961(gene)|ensembl:ENST00000318410(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0034629"|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051125"(regulation of actin nucleation)|go:"GO:0071203"(WASH complex)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0097494"(regulation of vesicle size)|go:"GO:0140285"(endosome fission)|interpro:IPR019393|mint:Q12768|refseq:XP_016869602.1	-	-	-	comment:VPS26A and/or VPS26B was also detected|figure legend:5B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2017/08/17	rogid:dK5TqSajxrGKjiNwRjeZCV519XE10090	rogid:9QEw0Z7NIOvpVJtWXcLp67ApJdk9606	intact-crc:7054BE894E237CBC|rigid:TOvA9I+CAqBiM8ZTnP3qGQKTp/c	false	green fluorescent protein tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9QZ88	uniprotkb:Q96QK1	intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020	intact:EBI-1054634|uniprotkb:Q561W2|uniprotkb:Q9H016|uniprotkb:Q9H096|uniprotkb:Q9H4P3|uniprotkb:Q9H8J0|uniprotkb:Q9NRS7|uniprotkb:Q9NVG2|uniprotkb:Q9NX80|uniprotkb:Q9NZK2|ensembl:ENSP00000299138	psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym)	psi-mi:vps35_human(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:VPS35(gene name)|psi-mi:VPS35(display_short)|uniprotkb:MEM3(gene name synonym)|uniprotkb:TCCCTA00141(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846898|imex:IM-26126-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome)	refseq:NP_060676.2|rcsb pdb:5F0J|rcsb pdb:5F0K|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|rcsb pdb:5OSH|rcsb pdb:5OSI|rcsb pdb:7BLN|rcsb pdb:7BLO|reactome:R-HSA-3238698|ensembl:ENSG00000069329(gene)|ensembl:ENST00000299138(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0097422"(tubular endosome)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|rcsb pdb:2R17|dip:DIP-29076N	-	function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint	-	comment:VPS26A and/or VPS26B was also detected|figure legend:6C|comment:Association of WASHC5/strumpellin was decreased upon treating cells independently with siRNAs to KIAA1033, RAB7 and SNX1. siRNAs to SNX3, WASH1, FKBP15 and TBC1D5 had no effect.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2017/08/14	rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090	rogid:EXkMduDQKNCdp876vGF5vna9t389606	intact-crc:2E4BFA32E0047AC6|rigid:EdxweDwhKuOjR+3McpL3HhjG6kQ	false	green fluorescent protein tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9QZ88	uniprotkb:Q12768	intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020	intact:EBI-2563794|uniprotkb:A8K4R7|uniprotkb:Q3KQX5|uniprotkb:Q8TBQ2|ensembl:ENSP00000318016	psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym)	psi-mi:wasc5_human(display_long)|uniprotkb:WASHC5(gene name)|psi-mi:WASHC5(display_short)|uniprotkb:KIAA0196(gene name synonym)|uniprotkb:Strumpellin(gene name synonym)|uniprotkb:WASH complex subunit strumpellin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846898|imex:IM-26126-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome)	refseq:NP_055661.3|ensembl:ENSG00000164961(gene)|ensembl:ENST00000318410(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0034629"|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051125"(regulation of actin nucleation)|go:"GO:0071203"(WASH complex)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0097494"(regulation of vesicle size)|go:"GO:0140285"(endosome fission)|interpro:IPR019393|mint:Q12768|refseq:XP_016869602.1	-	function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint	-	comment:VPS26A and/or VPS26B was also detected|figure legend:6C|comment:Association of WASHC5/strumpellin was decreased upon treating cells independently with siRNAs to KIAA1033, RAB7 and SNX1. siRNAs to SNX3, WASH1, FKBP15 and TBC1D5 had no effect.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2017/08/14	rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090	rogid:9QEw0Z7NIOvpVJtWXcLp67ApJdk9606	intact-crc:2E4BFA32E0047AC6|rigid:EdxweDwhKuOjR+3McpL3HhjG6kQ	false	green fluorescent protein tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9QZ88	uniprotkb:Q92609	intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020	intact:EBI-742381|uniprotkb:A6NP25|intact:EBI-28978959|ensembl:ENSP00000253692|ensembl:ENSP00000398127|uniprotkb:C9JP52	psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym)	psi-mi:tbcd5_human(display_long)|uniprotkb:TBC1D5(gene name)|psi-mi:TBC1D5(display_short)|uniprotkb:KIAA0210(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16362482|imex:IM-26126-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome)	ensembl:ENSP00000253692|ensembl:ENSP00000398127|ensembl:ENSP00000402935|ensembl:ENST00000446818|refseq:NP_055559.1|refseq:XP_011532586.1|refseq:XP_011532583.1|refseq:XP_011532585.1|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006914"(autophagy)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0035612"(AP-2 adaptor complex binding)|ensembl:ENSG00000131374(gene)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042594"(response to starvation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1905394"(retromer complex binding)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|mint:Q92609|rcsb pdb:5GTU|ensembl:ENST00000253692(transcript)|ensembl:ENST00000429383(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|refseq:NP_001127853.1|refseq:XP_006713493.1|refseq:XP_016863041.1|refseq:XP_016863042.1|refseq:XP_016863043.1|refseq:XP_016863044.1|refseq:XP_016863045.1|refseq:XP_016863046.1	-	function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint	-	figure legend:5B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2017/08/17	rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090	rogid:GZ7WP4suMiSPSAJK0TZWQMQZxzU9606	rigid:r1gUYAmjVdSMX/uBE88h5A0omZA	false	mutation:91-91|green fluorescent protein tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9QZ88	uniprotkb:Q5T1M5	intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020	intact:EBI-5235934|uniprotkb:Q05DK8|uniprotkb:Q5T1M2|uniprotkb:Q6DD85|uniprotkb:Q9Y4D0|ensembl:ENSP00000238256|ensembl:ENSP00000416158	psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym)	psi-mi:fkb15_human(display_long)|uniprotkb:FKBP15(gene name)|psi-mi:FKBP15(display_short)|uniprotkb:KIAA0674(gene name synonym)|uniprotkb:133 kDa FK506-binding protein(gene name synonym)|uniprotkb:WASP- and FKBP-like protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16362494|imex:IM-26126-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome)	refseq:NP_056073.1|refseq:XP_006717081.1|ensembl:ENSG00000119321(gene)|ensembl:ENST00000238256(transcript)|ensembl:ENST00000446284(transcript)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0003779"(actin binding)|go:"GO:0005769"(early endosome)|go:"GO:0006897"(endocytosis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030426"(growth cone)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|mint:Q5T1M5	-	function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint	-	figure legend:5B|comment:VPS26A and/or VPS26B was also detected|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2017/08/17	rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090	rogid:2th35ZHTzidVTyWGpc0Emz3foIY9606	rigid:JvP8aO2+uRtjvdYcgOLH8GAOFso	false	green fluorescent protein tag:c-c|mutation:152-152	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9QZ88	uniprotkb:Q96QK1	intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020	intact:EBI-1054634|uniprotkb:Q561W2|uniprotkb:Q9H016|uniprotkb:Q9H096|uniprotkb:Q9H4P3|uniprotkb:Q9H8J0|uniprotkb:Q9NRS7|uniprotkb:Q9NVG2|uniprotkb:Q9NX80|uniprotkb:Q9NZK2|ensembl:ENSP00000299138	psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym)	psi-mi:vps35_human(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:VPS35(gene name)|psi-mi:VPS35(display_short)|uniprotkb:MEM3(gene name synonym)|uniprotkb:TCCCTA00141(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16362494|imex:IM-26126-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome)	refseq:NP_060676.2|rcsb pdb:5F0J|rcsb pdb:5F0K|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|rcsb pdb:5OSH|rcsb pdb:5OSI|rcsb pdb:7BLN|rcsb pdb:7BLO|reactome:R-HSA-3238698|ensembl:ENSG00000069329(gene)|ensembl:ENST00000299138(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0097422"(tubular endosome)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|rcsb pdb:2R17|dip:DIP-29076N	-	function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint	-	figure legend:5B|comment:VPS26A and/or VPS26B was also detected|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2017/08/17	rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090	rogid:EXkMduDQKNCdp876vGF5vna9t389606	rigid:JvP8aO2+uRtjvdYcgOLH8GAOFso	false	green fluorescent protein tag:c-c|mutation:152-152	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9QZ88	uniprotkb:A8K0Z3	intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020	intact:EBI-6160405|intact:EBI-28977476|ensembl:ENSP00000485627	psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym)	psi-mi:wash1_human(display_long)|uniprotkb:WASHC1(gene name)|psi-mi:WASHC1(display_short)|uniprotkb:CXYorf1-like protein on chromosome 9(gene name synonym)|uniprotkb:FAM39E(gene name synonym)|uniprotkb:Protein FAM39E(gene name synonym)|uniprotkb:WAS protein family homolog 1(gene name synonym)|uniprotkb:WASH1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16362494|imex:IM-26126-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome)	ensembl:ENSP00000485627|refseq:NP_878908.4|ensembl:ENSG00000181404(gene)|ensembl:ENST00000442898(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031274"(positive regulation of pseudopodium assembly)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043553"(negative regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071203"(WASH complex)|interpro:IPR021854|interpro:IPR028290	-	function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint	-	figure legend:5B|comment:VPS26A and/or VPS26B was also detected|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2017/08/17	rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090	rogid:X7zdUL7YK2B6tU4RUdSTXrJfXLk9606	rigid:JvP8aO2+uRtjvdYcgOLH8GAOFso	false	green fluorescent protein tag:c-c|mutation:152-152	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9QZ88	uniprotkb:Q12768	intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020	intact:EBI-2563794|uniprotkb:A8K4R7|uniprotkb:Q3KQX5|uniprotkb:Q8TBQ2|ensembl:ENSP00000318016	psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym)	psi-mi:wasc5_human(display_long)|uniprotkb:WASHC5(gene name)|psi-mi:WASHC5(display_short)|uniprotkb:KIAA0196(gene name synonym)|uniprotkb:Strumpellin(gene name synonym)|uniprotkb:WASH complex subunit strumpellin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16362494|imex:IM-26126-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome)	refseq:NP_055661.3|ensembl:ENSG00000164961(gene)|ensembl:ENST00000318410(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0034629"|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051125"(regulation of actin nucleation)|go:"GO:0071203"(WASH complex)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0097494"(regulation of vesicle size)|go:"GO:0140285"(endosome fission)|interpro:IPR019393|mint:Q12768|refseq:XP_016869602.1	-	function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint	-	figure legend:5B|comment:VPS26A and/or VPS26B was also detected|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2017/08/17	rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090	rogid:9QEw0Z7NIOvpVJtWXcLp67ApJdk9606	rigid:JvP8aO2+uRtjvdYcgOLH8GAOFso	false	green fluorescent protein tag:c-c|mutation:152-152	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9QZ88	uniprotkb:Q5T1M5	intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020	intact:EBI-5235934|uniprotkb:Q05DK8|uniprotkb:Q5T1M2|uniprotkb:Q6DD85|uniprotkb:Q9Y4D0|ensembl:ENSP00000238256|ensembl:ENSP00000416158	psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym)	psi-mi:fkb15_human(display_long)|uniprotkb:FKBP15(gene name)|psi-mi:FKBP15(display_short)|uniprotkb:KIAA0674(gene name synonym)|uniprotkb:133 kDa FK506-binding protein(gene name synonym)|uniprotkb:WASP- and FKBP-like protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16362517|imex:IM-26126-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome)	refseq:NP_056073.1|refseq:XP_006717081.1|ensembl:ENSG00000119321(gene)|ensembl:ENST00000238256(transcript)|ensembl:ENST00000446284(transcript)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0003779"(actin binding)|go:"GO:0005769"(early endosome)|go:"GO:0006897"(endocytosis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030426"(growth cone)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|mint:Q5T1M5	-	function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint	-	figure legend:5B|comment:VPS26A and/or VPS26B was also detected|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2017/08/29	rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090	rogid:2th35ZHTzidVTyWGpc0Emz3foIY9606	rigid:4Nf2aYfp/TKwzR8VQ4Fge9FxRiY	false	green fluorescent protein tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9QZ88	uniprotkb:Q92609	intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020	intact:EBI-742381|uniprotkb:A6NP25|intact:EBI-28978959|ensembl:ENSP00000253692|ensembl:ENSP00000398127|uniprotkb:C9JP52	psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym)	psi-mi:tbcd5_human(display_long)|uniprotkb:TBC1D5(gene name)|psi-mi:TBC1D5(display_short)|uniprotkb:KIAA0210(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16362517|imex:IM-26126-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome)	ensembl:ENSP00000253692|ensembl:ENSP00000398127|ensembl:ENSP00000402935|ensembl:ENST00000446818|refseq:NP_055559.1|refseq:XP_011532586.1|refseq:XP_011532583.1|refseq:XP_011532585.1|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006914"(autophagy)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0035612"(AP-2 adaptor complex binding)|ensembl:ENSG00000131374(gene)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042594"(response to starvation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1905394"(retromer complex binding)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|mint:Q92609|rcsb pdb:5GTU|ensembl:ENST00000253692(transcript)|ensembl:ENST00000429383(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|refseq:NP_001127853.1|refseq:XP_006713493.1|refseq:XP_016863041.1|refseq:XP_016863042.1|refseq:XP_016863043.1|refseq:XP_016863044.1|refseq:XP_016863045.1|refseq:XP_016863046.1	-	function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint	-	figure legend:5B|comment:VPS26A and/or VPS26B was also detected|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2017/08/29	rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090	rogid:GZ7WP4suMiSPSAJK0TZWQMQZxzU9606	rigid:4Nf2aYfp/TKwzR8VQ4Fge9FxRiY	false	green fluorescent protein tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9QZ88	uniprotkb:Q96QK1	intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020	intact:EBI-1054634|uniprotkb:Q561W2|uniprotkb:Q9H016|uniprotkb:Q9H096|uniprotkb:Q9H4P3|uniprotkb:Q9H8J0|uniprotkb:Q9NRS7|uniprotkb:Q9NVG2|uniprotkb:Q9NX80|uniprotkb:Q9NZK2|ensembl:ENSP00000299138	psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym)	psi-mi:vps35_human(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:VPS35(gene name)|psi-mi:VPS35(display_short)|uniprotkb:MEM3(gene name synonym)|uniprotkb:TCCCTA00141(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16362517|imex:IM-26126-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome)	refseq:NP_060676.2|rcsb pdb:5F0J|rcsb pdb:5F0K|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|rcsb pdb:5OSH|rcsb pdb:5OSI|rcsb pdb:7BLN|rcsb pdb:7BLO|reactome:R-HSA-3238698|ensembl:ENSG00000069329(gene)|ensembl:ENST00000299138(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0097422"(tubular endosome)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|rcsb pdb:2R17|dip:DIP-29076N	-	function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint	-	figure legend:5B|comment:VPS26A and/or VPS26B was also detected|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2017/08/29	rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090	rogid:EXkMduDQKNCdp876vGF5vna9t389606	rigid:4Nf2aYfp/TKwzR8VQ4Fge9FxRiY	false	green fluorescent protein tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9QZ88	uniprotkb:A8K0Z3	intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020	intact:EBI-6160405|intact:EBI-28977476|ensembl:ENSP00000485627	psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym)	psi-mi:wash1_human(display_long)|uniprotkb:WASHC1(gene name)|psi-mi:WASHC1(display_short)|uniprotkb:CXYorf1-like protein on chromosome 9(gene name synonym)|uniprotkb:FAM39E(gene name synonym)|uniprotkb:Protein FAM39E(gene name synonym)|uniprotkb:WAS protein family homolog 1(gene name synonym)|uniprotkb:WASH1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16362517|imex:IM-26126-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome)	ensembl:ENSP00000485627|refseq:NP_878908.4|ensembl:ENSG00000181404(gene)|ensembl:ENST00000442898(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031274"(positive regulation of pseudopodium assembly)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043553"(negative regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071203"(WASH complex)|interpro:IPR021854|interpro:IPR028290	-	function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint	-	figure legend:5B|comment:VPS26A and/or VPS26B was also detected|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2017/08/29	rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090	rogid:X7zdUL7YK2B6tU4RUdSTXrJfXLk9606	rigid:4Nf2aYfp/TKwzR8VQ4Fge9FxRiY	false	green fluorescent protein tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9QZ88	uniprotkb:Q12768	intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020	intact:EBI-2563794|uniprotkb:A8K4R7|uniprotkb:Q3KQX5|uniprotkb:Q8TBQ2|ensembl:ENSP00000318016	psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym)	psi-mi:wasc5_human(display_long)|uniprotkb:WASHC5(gene name)|psi-mi:WASHC5(display_short)|uniprotkb:KIAA0196(gene name synonym)|uniprotkb:Strumpellin(gene name synonym)|uniprotkb:WASH complex subunit strumpellin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16362517|imex:IM-26126-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome)	refseq:NP_055661.3|ensembl:ENSG00000164961(gene)|ensembl:ENST00000318410(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0034629"|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051125"(regulation of actin nucleation)|go:"GO:0071203"(WASH complex)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0097494"(regulation of vesicle size)|go:"GO:0140285"(endosome fission)|interpro:IPR019393|mint:Q12768|refseq:XP_016869602.1	-	function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint	-	figure legend:5B|comment:VPS26A and/or VPS26B was also detected|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2017/08/29	rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090	rogid:9QEw0Z7NIOvpVJtWXcLp67ApJdk9606	rigid:4Nf2aYfp/TKwzR8VQ4Fge9FxRiY	false	green fluorescent protein tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q92609	uniprotkb:Q12768	intact:EBI-742381|uniprotkb:A6NP25|intact:EBI-28978959|ensembl:ENSP00000253692|ensembl:ENSP00000398127|uniprotkb:C9JP52	intact:EBI-2563794|uniprotkb:A8K4R7|uniprotkb:Q3KQX5|uniprotkb:Q8TBQ2|ensembl:ENSP00000318016	psi-mi:tbcd5_human(display_long)|uniprotkb:TBC1D5(gene name)|psi-mi:TBC1D5(display_short)|uniprotkb:KIAA0210(gene name synonym)	psi-mi:wasc5_human(display_long)|uniprotkb:WASHC5(gene name)|psi-mi:WASHC5(display_short)|uniprotkb:KIAA0196(gene name synonym)|uniprotkb:Strumpellin(gene name synonym)|uniprotkb:WASH complex subunit strumpellin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16398192|imex:IM-26126-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000253692|ensembl:ENSP00000398127|ensembl:ENSP00000402935|ensembl:ENST00000446818|refseq:NP_055559.1|refseq:XP_011532586.1|refseq:XP_011532583.1|refseq:XP_011532585.1|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006914"(autophagy)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0035612"(AP-2 adaptor complex binding)|ensembl:ENSG00000131374(gene)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042594"(response to starvation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1905394"(retromer complex binding)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|mint:Q92609|rcsb pdb:5GTU|ensembl:ENST00000253692(transcript)|ensembl:ENST00000429383(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|refseq:NP_001127853.1|refseq:XP_006713493.1|refseq:XP_016863041.1|refseq:XP_016863042.1|refseq:XP_016863043.1|refseq:XP_016863044.1|refseq:XP_016863045.1|refseq:XP_016863046.1	refseq:NP_055661.3|ensembl:ENSG00000164961(gene)|ensembl:ENST00000318410(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0034629"|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051125"(regulation of actin nucleation)|go:"GO:0071203"(WASH complex)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0097494"(regulation of vesicle size)|go:"GO:0140285"(endosome fission)|interpro:IPR019393|mint:Q12768|refseq:XP_016869602.1	-	comment:TBC1D5 mutant constructs R169A, Q204A, R169A, Q204A and SST43AAA also showed association	-	figure legend:5B|comment:VPS26A and/or VPS26B was also detected|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2017/08/29	rogid:GZ7WP4suMiSPSAJK0TZWQMQZxzU9606	rogid:9QEw0Z7NIOvpVJtWXcLp67ApJdk9606	rigid:Luw3PKzWxQOKIbD+nqLPi/0RXos	false	green fluorescent protein tag:?-?|mutation:204-204,169-169	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q92609	uniprotkb:Q96QK1	intact:EBI-742381|uniprotkb:A6NP25|intact:EBI-28978959|ensembl:ENSP00000253692|ensembl:ENSP00000398127|uniprotkb:C9JP52	intact:EBI-1054634|uniprotkb:Q561W2|uniprotkb:Q9H016|uniprotkb:Q9H096|uniprotkb:Q9H4P3|uniprotkb:Q9H8J0|uniprotkb:Q9NRS7|uniprotkb:Q9NVG2|uniprotkb:Q9NX80|uniprotkb:Q9NZK2|ensembl:ENSP00000299138	psi-mi:tbcd5_human(display_long)|uniprotkb:TBC1D5(gene name)|psi-mi:TBC1D5(display_short)|uniprotkb:KIAA0210(gene name synonym)	psi-mi:vps35_human(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:VPS35(gene name)|psi-mi:VPS35(display_short)|uniprotkb:MEM3(gene name synonym)|uniprotkb:TCCCTA00141(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16398192|imex:IM-26126-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000253692|ensembl:ENSP00000398127|ensembl:ENSP00000402935|ensembl:ENST00000446818|refseq:NP_055559.1|refseq:XP_011532586.1|refseq:XP_011532583.1|refseq:XP_011532585.1|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006914"(autophagy)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0035612"(AP-2 adaptor complex binding)|ensembl:ENSG00000131374(gene)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042594"(response to starvation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1905394"(retromer complex binding)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|mint:Q92609|rcsb pdb:5GTU|ensembl:ENST00000253692(transcript)|ensembl:ENST00000429383(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|refseq:NP_001127853.1|refseq:XP_006713493.1|refseq:XP_016863041.1|refseq:XP_016863042.1|refseq:XP_016863043.1|refseq:XP_016863044.1|refseq:XP_016863045.1|refseq:XP_016863046.1	refseq:NP_060676.2|rcsb pdb:5F0J|rcsb pdb:5F0K|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|rcsb pdb:5OSH|rcsb pdb:5OSI|rcsb pdb:7BLN|rcsb pdb:7BLO|reactome:R-HSA-3238698|ensembl:ENSG00000069329(gene)|ensembl:ENST00000299138(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0097422"(tubular endosome)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|rcsb pdb:2R17|dip:DIP-29076N	-	comment:TBC1D5 mutant constructs R169A, Q204A, R169A, Q204A and SST43AAA also showed association	-	figure legend:5B|comment:VPS26A and/or VPS26B was also detected|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2017/08/29	rogid:GZ7WP4suMiSPSAJK0TZWQMQZxzU9606	rogid:EXkMduDQKNCdp876vGF5vna9t389606	rigid:Luw3PKzWxQOKIbD+nqLPi/0RXos	false	green fluorescent protein tag:?-?|mutation:204-204,169-169	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5T1M5	uniprotkb:Q12768	intact:EBI-5235934|uniprotkb:Q05DK8|uniprotkb:Q5T1M2|uniprotkb:Q6DD85|uniprotkb:Q9Y4D0|ensembl:ENSP00000238256|ensembl:ENSP00000416158	intact:EBI-2563794|uniprotkb:A8K4R7|uniprotkb:Q3KQX5|uniprotkb:Q8TBQ2|ensembl:ENSP00000318016	psi-mi:fkb15_human(display_long)|uniprotkb:FKBP15(gene name)|psi-mi:FKBP15(display_short)|uniprotkb:KIAA0674(gene name synonym)|uniprotkb:133 kDa FK506-binding protein(gene name synonym)|uniprotkb:WASP- and FKBP-like protein(gene name synonym)	psi-mi:wasc5_human(display_long)|uniprotkb:WASHC5(gene name)|psi-mi:WASHC5(display_short)|uniprotkb:KIAA0196(gene name synonym)|uniprotkb:Strumpellin(gene name synonym)|uniprotkb:WASH complex subunit strumpellin(gene name synonym)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846750|imex:IM-26126-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056073.1|refseq:XP_006717081.1|ensembl:ENSG00000119321(gene)|ensembl:ENST00000238256(transcript)|ensembl:ENST00000446284(transcript)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0003779"(actin binding)|go:"GO:0005769"(early endosome)|go:"GO:0006897"(endocytosis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030426"(growth cone)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|mint:Q5T1M5	refseq:NP_055661.3|ensembl:ENSG00000164961(gene)|ensembl:ENST00000318410(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0034629"|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051125"(regulation of actin nucleation)|go:"GO:0071203"(WASH complex)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0097494"(regulation of vesicle size)|go:"GO:0140285"(endosome fission)|interpro:IPR019393|mint:Q12768|refseq:XP_016869602.1	-	-	-	figure legend:6B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2017/08/29	rogid:2th35ZHTzidVTyWGpc0Emz3foIY9606	rogid:9QEw0Z7NIOvpVJtWXcLp67ApJdk9606	intact-crc:D8F464B5461DE7D0|rigid:Y0vh4OR2RWvHnqHzShgrnVmFj68	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5T1M5	uniprotkb:A8K0Z3	intact:EBI-5235934|uniprotkb:Q05DK8|uniprotkb:Q5T1M2|uniprotkb:Q6DD85|uniprotkb:Q9Y4D0|ensembl:ENSP00000238256|ensembl:ENSP00000416158	intact:EBI-6160405|intact:EBI-28977476|ensembl:ENSP00000485627	psi-mi:fkb15_human(display_long)|uniprotkb:FKBP15(gene name)|psi-mi:FKBP15(display_short)|uniprotkb:KIAA0674(gene name synonym)|uniprotkb:133 kDa FK506-binding protein(gene name synonym)|uniprotkb:WASP- and FKBP-like protein(gene name synonym)	psi-mi:wash1_human(display_long)|uniprotkb:WASHC1(gene name)|psi-mi:WASHC1(display_short)|uniprotkb:CXYorf1-like protein on chromosome 9(gene name synonym)|uniprotkb:FAM39E(gene name synonym)|uniprotkb:Protein FAM39E(gene name synonym)|uniprotkb:WAS protein family homolog 1(gene name synonym)|uniprotkb:WASH1(gene name synonym)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846750|imex:IM-26126-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056073.1|refseq:XP_006717081.1|ensembl:ENSG00000119321(gene)|ensembl:ENST00000238256(transcript)|ensembl:ENST00000446284(transcript)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0003779"(actin binding)|go:"GO:0005769"(early endosome)|go:"GO:0006897"(endocytosis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030426"(growth cone)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|mint:Q5T1M5	ensembl:ENSP00000485627|refseq:NP_878908.4|ensembl:ENSG00000181404(gene)|ensembl:ENST00000442898(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031274"(positive regulation of pseudopodium assembly)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043553"(negative regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071203"(WASH complex)|interpro:IPR021854|interpro:IPR028290	-	-	-	figure legend:6B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2017/08/29	rogid:2th35ZHTzidVTyWGpc0Emz3foIY9606	rogid:X7zdUL7YK2B6tU4RUdSTXrJfXLk9606	intact-crc:D8F464B5461DE7D0|rigid:Y0vh4OR2RWvHnqHzShgrnVmFj68	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5T1M5	uniprotkb:Q9QZ88	intact:EBI-5235934|uniprotkb:Q05DK8|uniprotkb:Q5T1M2|uniprotkb:Q6DD85|uniprotkb:Q9Y4D0|ensembl:ENSP00000238256|ensembl:ENSP00000416158	intact:EBI-8334188|intact:MINT-4140090|uniprotkb:Q9D107|uniprotkb:Q3UCZ0|ensembl:ENSMUSP00000121020	psi-mi:fkb15_human(display_long)|uniprotkb:FKBP15(gene name)|psi-mi:FKBP15(display_short)|uniprotkb:KIAA0674(gene name synonym)|uniprotkb:133 kDa FK506-binding protein(gene name synonym)|uniprotkb:WASP- and FKBP-like protein(gene name synonym)	psi-mi:vps29_mouse(display_long)|uniprotkb:Vps29(gene name)|psi-mi:Vps29(display_short)|uniprotkb:Vesicle protein sorting 29(gene name synonym)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846738|imex:IM-26126-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056073.1|refseq:XP_006717081.1|ensembl:ENSG00000119321(gene)|ensembl:ENST00000238256(transcript)|ensembl:ENST00000446284(transcript)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0003779"(actin binding)|go:"GO:0005769"(early endosome)|go:"GO:0006897"(endocytosis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030426"(growth cone)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|mint:Q5T1M5	refseq:NP_062754.1|refseq:NP_001334382.1|dip:DIP-60495N|ensembl:ENSMUSG00000029462(gene)|ensembl:ENSMUST00000155671(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9QZ88|rcsb pdb:1Z2W|rcsb pdb:1Z2X|rcsb pdb:3PSN|rcsb pdb:3PSO|rcsb pdb:6TL0|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698|go:"GO:0005768"(endosome)	-	-	function:"Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro)"|comment:mint	figure legend:6B|comment:VPS26A or VPS26B comigrated|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2017/08/29	rogid:2th35ZHTzidVTyWGpc0Emz3foIY9606	rogid:XLAmkQXgIRvAF4JDcavWOR9CnsY10090	intact-crc:FDD212C0DE5FA2BE|rigid:F4INe3HNQdvMXsQhiUm3Kh5RRJA	false	-	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5T1M5	uniprotkb:Q96QK1	intact:EBI-5235934|uniprotkb:Q05DK8|uniprotkb:Q5T1M2|uniprotkb:Q6DD85|uniprotkb:Q9Y4D0|ensembl:ENSP00000238256|ensembl:ENSP00000416158	intact:EBI-1054634|uniprotkb:Q561W2|uniprotkb:Q9H016|uniprotkb:Q9H096|uniprotkb:Q9H4P3|uniprotkb:Q9H8J0|uniprotkb:Q9NRS7|uniprotkb:Q9NVG2|uniprotkb:Q9NX80|uniprotkb:Q9NZK2|ensembl:ENSP00000299138	psi-mi:fkb15_human(display_long)|uniprotkb:FKBP15(gene name)|psi-mi:FKBP15(display_short)|uniprotkb:KIAA0674(gene name synonym)|uniprotkb:133 kDa FK506-binding protein(gene name synonym)|uniprotkb:WASP- and FKBP-like protein(gene name synonym)	psi-mi:vps35_human(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:VPS35(gene name)|psi-mi:VPS35(display_short)|uniprotkb:MEM3(gene name synonym)|uniprotkb:TCCCTA00141(orf name)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846738|imex:IM-26126-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056073.1|refseq:XP_006717081.1|ensembl:ENSG00000119321(gene)|ensembl:ENST00000238256(transcript)|ensembl:ENST00000446284(transcript)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0003779"(actin binding)|go:"GO:0005769"(early endosome)|go:"GO:0006897"(endocytosis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030426"(growth cone)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|mint:Q5T1M5	refseq:NP_060676.2|rcsb pdb:5F0J|rcsb pdb:5F0K|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|rcsb pdb:5OSH|rcsb pdb:5OSI|rcsb pdb:7BLN|rcsb pdb:7BLO|reactome:R-HSA-3238698|ensembl:ENSG00000069329(gene)|ensembl:ENST00000299138(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0097422"(tubular endosome)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|rcsb pdb:2R17|dip:DIP-29076N	-	-	-	figure legend:6B|comment:VPS26A or VPS26B comigrated|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2017/08/29	rogid:2th35ZHTzidVTyWGpc0Emz3foIY9606	rogid:EXkMduDQKNCdp876vGF5vna9t389606	intact-crc:FDD212C0DE5FA2BE|rigid:F4INe3HNQdvMXsQhiUm3Kh5RRJA	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q13596	uniprotkb:Q12768	intact:EBI-2822329|uniprotkb:O60750|uniprotkb:A8K6T7|uniprotkb:A6NM19|uniprotkb:O60751|uniprotkb:H0Y2M5|uniprotkb:Q6ZRJ8|ensembl:ENSP00000453785	intact:EBI-2563794|uniprotkb:A8K4R7|uniprotkb:Q3KQX5|uniprotkb:Q8TBQ2|ensembl:ENSP00000318016	psi-mi:snx1_human(display_long)|uniprotkb:SNX1(gene name)|psi-mi:SNX1(display_short)	psi-mi:wasc5_human(display_long)|uniprotkb:WASHC5(gene name)|psi-mi:WASHC5(display_short)|uniprotkb:KIAA0196(gene name synonym)|uniprotkb:Strumpellin(gene name synonym)|uniprotkb:WASH complex subunit strumpellin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9846999|imex:IM-26126-39	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003090.2|refseq:NP_683758.1|refseq:NP_001229862.1|ensembl:ENSG00000028528(gene)|ensembl:ENST00000559844(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030904"(retromer complex)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0031623"(receptor internalization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0072673"(lamellipodium morphogenesis)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990460"(leptin receptor binding)|interpro:IPR001683(Phox-like)|interpro:IPR005329(Sorting nexin, N-terminal)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028660|interpro:IPR034901|mint:Q13596|rcsb pdb:2I4K|rcsb pdb:4FZS|interpro:IPR036871|dip:DIP-398N	refseq:NP_055661.3|ensembl:ENSG00000164961(gene)|ensembl:ENST00000318410(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0034629"|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051125"(regulation of actin nucleation)|go:"GO:0071203"(WASH complex)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0097494"(regulation of vesicle size)|go:"GO:0140285"(endosome fission)|interpro:IPR019393|mint:Q12768|refseq:XP_016869602.1	-	-	-	figure legend:9A and B|comment:Treating cells with siRNA to TBC1D5 decreased association.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2017/09/13	rogid:nFyxCtQ9gHndLbuCjBiwhyWE5do9606	rogid:9QEw0Z7NIOvpVJtWXcLp67ApJdk9606	intact-crc:3EF5FDFC9F78E41E|rigid:i0XjBw3Txs0Bxa4AeuVq7j4B7FI	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q13596	uniprotkb:Q12768	intact:EBI-2822329|uniprotkb:O60750|uniprotkb:A8K6T7|uniprotkb:A6NM19|uniprotkb:O60751|uniprotkb:H0Y2M5|uniprotkb:Q6ZRJ8|ensembl:ENSP00000453785	intact:EBI-2563794|uniprotkb:A8K4R7|uniprotkb:Q3KQX5|uniprotkb:Q8TBQ2|ensembl:ENSP00000318016	psi-mi:snx1_human(display_long)|uniprotkb:SNX1(gene name)|psi-mi:SNX1(display_short)	psi-mi:wasc5_human(display_long)|uniprotkb:WASHC5(gene name)|psi-mi:WASHC5(display_short)|uniprotkb:KIAA0196(gene name synonym)|uniprotkb:Strumpellin(gene name synonym)|uniprotkb:WASH complex subunit strumpellin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16364840|imex:IM-26126-41	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003090.2|refseq:NP_683758.1|refseq:NP_001229862.1|ensembl:ENSG00000028528(gene)|ensembl:ENST00000559844(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030904"(retromer complex)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0031623"(receptor internalization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0072673"(lamellipodium morphogenesis)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990460"(leptin receptor binding)|interpro:IPR001683(Phox-like)|interpro:IPR005329(Sorting nexin, N-terminal)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028660|interpro:IPR034901|mint:Q13596|rcsb pdb:2I4K|rcsb pdb:4FZS|interpro:IPR036871|dip:DIP-398N	refseq:NP_055661.3|ensembl:ENSG00000164961(gene)|ensembl:ENST00000318410(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0034629"|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051125"(regulation of actin nucleation)|go:"GO:0071203"(WASH complex)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0097494"(regulation of vesicle size)|go:"GO:0140285"(endosome fission)|interpro:IPR019393|mint:Q12768|refseq:XP_016869602.1	-	-	-	figure legend:9A|comment:Treating cells with siRNA to TBC1D5 decreased association.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2017/08/22	rogid:nFyxCtQ9gHndLbuCjBiwhyWE5do9606	rogid:9QEw0Z7NIOvpVJtWXcLp67ApJdk9606	rigid:i0XjBw3Txs0Bxa4AeuVq7j4B7FI	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:A8K0Z3	uniprotkb:Q5T1M5	intact:EBI-6160405|intact:EBI-28977476|ensembl:ENSP00000485627	intact:EBI-5235934|uniprotkb:Q05DK8|uniprotkb:Q5T1M2|uniprotkb:Q6DD85|uniprotkb:Q9Y4D0|ensembl:ENSP00000238256|ensembl:ENSP00000416158	psi-mi:wash1_human(display_long)|uniprotkb:WASHC1(gene name)|psi-mi:WASHC1(display_short)|uniprotkb:CXYorf1-like protein on chromosome 9(gene name synonym)|uniprotkb:FAM39E(gene name synonym)|uniprotkb:Protein FAM39E(gene name synonym)|uniprotkb:WAS protein family homolog 1(gene name synonym)|uniprotkb:WASH1(gene name synonym)	psi-mi:fkb15_human(display_long)|uniprotkb:FKBP15(gene name)|psi-mi:FKBP15(display_short)|uniprotkb:KIAA0674(gene name synonym)|uniprotkb:133 kDa FK506-binding protein(gene name synonym)|uniprotkb:WASP- and FKBP-like protein(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16364882|imex:IM-26126-43	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000485627|refseq:NP_878908.4|ensembl:ENSG00000181404(gene)|ensembl:ENST00000442898(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031274"(positive regulation of pseudopodium assembly)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043553"(negative regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071203"(WASH complex)|interpro:IPR021854|interpro:IPR028290	refseq:NP_056073.1|refseq:XP_006717081.1|ensembl:ENSG00000119321(gene)|ensembl:ENST00000238256(transcript)|ensembl:ENST00000446284(transcript)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0003779"(actin binding)|go:"GO:0005769"(early endosome)|go:"GO:0006897"(endocytosis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030426"(growth cone)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|mint:Q5T1M5	go:"GO:0005768"(endosome)	-	-	figure legend:7D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2017/08/22	rogid:X7zdUL7YK2B6tU4RUdSTXrJfXLk9606	rogid:2th35ZHTzidVTyWGpc0Emz3foIY9606	rigid:pNDMB7nhTfXlXqT7UiB/yq7agYg	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:A8K0Z3	uniprotkb:Q13596	intact:EBI-6160405|intact:EBI-28977476|ensembl:ENSP00000485627	intact:EBI-2822329|uniprotkb:O60750|uniprotkb:A8K6T7|uniprotkb:A6NM19|uniprotkb:O60751|uniprotkb:H0Y2M5|uniprotkb:Q6ZRJ8|ensembl:ENSP00000453785	psi-mi:wash1_human(display_long)|uniprotkb:WASHC1(gene name)|psi-mi:WASHC1(display_short)|uniprotkb:CXYorf1-like protein on chromosome 9(gene name synonym)|uniprotkb:FAM39E(gene name synonym)|uniprotkb:Protein FAM39E(gene name synonym)|uniprotkb:WAS protein family homolog 1(gene name synonym)|uniprotkb:WASH1(gene name synonym)	psi-mi:snx1_human(display_long)|uniprotkb:SNX1(gene name)|psi-mi:SNX1(display_short)	psi-mi:"MI:0416"(fluorescence microscopy)	Harbour et al. (2010)	pubmed:20923837|imex:IM-26126	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16398351|imex:IM-26126-45	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000485627|refseq:NP_878908.4|ensembl:ENSG00000181404(gene)|ensembl:ENST00000442898(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031274"(positive regulation of pseudopodium assembly)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043553"(negative regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071203"(WASH complex)|interpro:IPR021854|interpro:IPR028290	refseq:NP_003090.2|refseq:NP_683758.1|refseq:NP_001229862.1|ensembl:ENSG00000028528(gene)|ensembl:ENST00000559844(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030904"(retromer complex)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0031623"(receptor internalization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0072673"(lamellipodium morphogenesis)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990460"(leptin receptor binding)|interpro:IPR001683(Phox-like)|interpro:IPR005329(Sorting nexin, N-terminal)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028660|interpro:IPR034901|mint:Q13596|rcsb pdb:2I4K|rcsb pdb:4FZS|interpro:IPR036871|dip:DIP-398N	go:"GO:0005768"(endosome)	-	-	figure legend:7A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/10/14	2017/08/29	rogid:X7zdUL7YK2B6tU4RUdSTXrJfXLk9606	rogid:nFyxCtQ9gHndLbuCjBiwhyWE5do9606	rigid:AfC+r8c3an6fqCCGgI43YGA5yF0	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)