#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P32915 uniprotkb:P35179 intact:EBI-16400|ensemblfungi:YLR378C|uniprotkb:D6VZ14 intact:EBI-16406|ensemblfungi:YDR086C|uniprotkb:D6VS73 psi-mi:sc61a_yeast(display_long)|uniprotkb:Sec61 complex subunit SEC61(gene name synonym)|uniprotkb:L3502.5(orf name)|uniprotkb:YLR378C(locus name)|uniprotkb:SEC61(gene name)|psi-mi:SEC61(display_short)|uniprotkb:Sec61 complex subunit alpha(gene name synonym) psi-mi:sc61g_yeast(display_long)|uniprotkb:Sec61 complex subunit SSS1(gene name synonym)|uniprotkb:Ssh1 complex subunit SSS1(gene name synonym)|uniprotkb:D4475(orf name)|uniprotkb:YDR086C(locus name)|uniprotkb:SSS1(gene name)|psi-mi:SSS1(display_short)|uniprotkb:Sec61 complex subunit gamma(gene name synonym)|uniprotkb:Ssh1 complex subunit gamma(gene name synonym) psi-mi:"MI:0808"(comigration in sds page) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9352295|imex:IM-22312-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0070843"(misfolded protein transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|go:"GO:0044743"(protein transmembrane import into intracellular organelle)|ensemblfungi:YLR378C(gene)|ensemblfungi:YLR378C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|refseq:NP_013482.1|sgd:S000004370|dip:DIP-2433N|mint:P32915 ensemblfungi:YDR086C(gene)|ensemblfungi:YDR086C_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0071261"(Ssh1 translocon complex)|interpro:IPR001901(Protein secE/sec61-gamma protein)|interpro:IPR008158(Protein translocase SEC61 complex gamma subunit)|interpro:IPR023391|rcsb pdb:2WW9|rcsb pdb:2WWA|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|reactome:R-SCE-9609523|refseq:NP_010371.1|sgd:S000002493|dip:DIP-2432N|mint:P35179 - - - figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/04/04 2014/10/16 rogid:Gi0aAi/lO9gi5h6LMgke4advNsM559292 rogid:QIi5kN/8mDxTSvxRiJVi2JsPdws559292 intact-crc:2C8083114249F009|rigid:fGIPEwnMjBuSO8ynM2u01ptfj6Q false alexa label:?-? alexa label:?-? 1 1 psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P32915 uniprotkb:P21825 intact:EBI-16400|ensemblfungi:YLR378C|uniprotkb:D6VZ14 intact:EBI-16632|ensemblfungi:YPL094C|uniprotkb:D6W3S3 psi-mi:sc61a_yeast(display_long)|uniprotkb:Sec61 complex subunit SEC61(gene name synonym)|uniprotkb:L3502.5(orf name)|uniprotkb:YLR378C(locus name)|uniprotkb:SEC61(gene name)|psi-mi:SEC61(display_short)|uniprotkb:Sec61 complex subunit alpha(gene name synonym) psi-mi:sec62_yeast(display_long)|uniprotkb:SEC62(gene name)|psi-mi:SEC62(display_short)|uniprotkb:YPL094C(locus name)|uniprotkb:LPG14C(orf name)|uniprotkb:Sec62/63 complex 30 kDa subunit(gene name synonym) psi-mi:"MI:0808"(comigration in sds page) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9352295|imex:IM-22312-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0070843"(misfolded protein transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|go:"GO:0044743"(protein transmembrane import into intracellular organelle)|ensemblfungi:YLR378C(gene)|ensemblfungi:YLR378C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|refseq:NP_013482.1|sgd:S000004370|dip:DIP-2433N|mint:P32915 ensemblfungi:YPL094C(gene)|ensemblfungi:YPL094C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|interpro:IPR004728(Translocation protein Sec62)|interpro:IPR011553(Translocation protein Sec62, ascomycota)|rcsb pdb:6ZZZ|rcsb pdb:7AFT|refseq:NP_015231.2|sgd:S000006015|dip:DIP-3827N|mint:P21825 - - - figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/04/04 2014/10/16 rogid:Gi0aAi/lO9gi5h6LMgke4advNsM559292 rogid:ntcNjurhtyRtHO3uJOOcJXb2Meg559292 intact-crc:2C8083114249F009|rigid:fGIPEwnMjBuSO8ynM2u01ptfj6Q false alexa label:?-? alexa label:?-?|ha tag:c-c 1 1 psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P32915 uniprotkb:P14906 intact:EBI-16400|ensemblfungi:YLR378C|uniprotkb:D6VZ14 intact:EBI-16636|uniprotkb:Q08690|ensemblfungi:YOR254C|uniprotkb:D6W2V5 psi-mi:sc61a_yeast(display_long)|uniprotkb:Sec61 complex subunit SEC61(gene name synonym)|uniprotkb:L3502.5(orf name)|uniprotkb:YLR378C(locus name)|uniprotkb:SEC61(gene name)|psi-mi:SEC61(display_short)|uniprotkb:Sec61 complex subunit alpha(gene name synonym) psi-mi:sec63_yeast(display_long)|uniprotkb:PTL1(gene name synonym)|uniprotkb:YOR254C(locus name)|uniprotkb:SEC63(gene name)|psi-mi:SEC63(display_short)|uniprotkb:NPL1(gene name synonym)|uniprotkb:Sec62/63 complex 73 kDa subunit(gene name synonym)|uniprotkb:Protein NPL1(gene name synonym) psi-mi:"MI:0808"(comigration in sds page) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9352295|imex:IM-22312-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0070843"(misfolded protein transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|go:"GO:0044743"(protein transmembrane import into intracellular organelle)|ensemblfungi:YLR378C(gene)|ensemblfungi:YLR378C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|refseq:NP_013482.1|sgd:S000004370|dip:DIP-2433N|mint:P32915 ensemblfungi:YOR254C(gene)|ensemblfungi:YOR254C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|go:"GO:0046967"(cytosol to endoplasmic reticulum transport)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004179(Sec63)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR018253|interpro:IPR027137|interpro:IPR036869|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAI|rcsb pdb:7KAU|rcsb pdb:7KB5|refseq:NP_014897.1|sgd:S000005780|dip:DIP-2396N|mint:P14906 - - - figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/04/04 2014/10/16 rogid:Gi0aAi/lO9gi5h6LMgke4advNsM559292 rogid:FcVMvm368fBcw0EH918+lqynntc559292 intact-crc:2C8083114249F009|rigid:fGIPEwnMjBuSO8ynM2u01ptfj6Q false alexa label:?-? alexa label:?-? 1 1 psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P32915 uniprotkb:P33754 intact:EBI-16400|ensemblfungi:YLR378C|uniprotkb:D6VZ14 intact:EBI-16647|ensemblfungi:YBR171W|uniprotkb:D6VQG7 psi-mi:sc61a_yeast(display_long)|uniprotkb:Sec61 complex subunit SEC61(gene name synonym)|uniprotkb:L3502.5(orf name)|uniprotkb:YLR378C(locus name)|uniprotkb:SEC61(gene name)|psi-mi:SEC61(display_short)|uniprotkb:Sec61 complex subunit alpha(gene name synonym) psi-mi:sec66_yeast(display_long)|uniprotkb:SEC71(gene name synonym)|uniprotkb:YBR1232(orf name)|uniprotkb:YBR171W(locus name)|uniprotkb:SEC66(gene name)|psi-mi:SEC66(display_short)|uniprotkb:HSS1(gene name synonym)|uniprotkb:Sec62/63 complex 31.5 kDa subunit(gene name synonym)|uniprotkb:Protein HSS1(gene name synonym) psi-mi:"MI:0808"(comigration in sds page) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9352295|imex:IM-22312-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0070843"(misfolded protein transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|go:"GO:0044743"(protein transmembrane import into intracellular organelle)|ensemblfungi:YLR378C(gene)|ensemblfungi:YLR378C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|refseq:NP_013482.1|sgd:S000004370|dip:DIP-2433N|mint:P32915 refseq:NP_009730.3|ensemblfungi:YBR171W(gene)|ensemblfungi:YBR171W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030447"(filamentous growth)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|go:"GO:0071944"(cell periphery)|interpro:IPR018624|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|sgd:S000000375|dip:DIP-1694N|mint:P33754 - - crc64:E2A8BB4994A227D4 figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/04/04 2014/10/16 rogid:Gi0aAi/lO9gi5h6LMgke4advNsM559292 rogid:KvIn7euv+AwTIngwnUh/lmdLyaw559292 intact-crc:2C8083114249F009|rigid:fGIPEwnMjBuSO8ynM2u01ptfj6Q false alexa label:?-? alexa label:?-? 1 1 psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P32915 uniprotkb:P39742 intact:EBI-16400|ensemblfungi:YLR378C|uniprotkb:D6VZ14 intact:EBI-16651|ensemblfungi:YLR292C|uniprotkb:D6VYT8 psi-mi:sc61a_yeast(display_long)|uniprotkb:Sec61 complex subunit SEC61(gene name synonym)|uniprotkb:L3502.5(orf name)|uniprotkb:YLR378C(locus name)|uniprotkb:SEC61(gene name)|psi-mi:SEC61(display_short)|uniprotkb:Sec61 complex subunit alpha(gene name synonym) psi-mi:sec72_yeast(display_long)|uniprotkb:SEC67(gene name synonym)|uniprotkb:SIM2(gene name synonym)|uniprotkb:L8003.18(orf name)|uniprotkb:YLR292C(locus name)|uniprotkb:SEC72(gene name)|psi-mi:SEC72(display_short)|uniprotkb:Sec62/63 complex 23 kDa subunit(gene name synonym) psi-mi:"MI:0808"(comigration in sds page) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9352295|imex:IM-22312-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0070843"(misfolded protein transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|go:"GO:0044743"(protein transmembrane import into intracellular organelle)|ensemblfungi:YLR378C(gene)|ensemblfungi:YLR378C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|refseq:NP_013482.1|sgd:S000004370|dip:DIP-2433N|mint:P32915 ensemblfungi:YLR292C(gene)|ensemblfungi:YLR292C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAJ|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|rcsb pdb:7KAO|rcsb pdb:7KAP|refseq:NP_013395.1|sgd:S000004283|dip:DIP-2491N|mint:P39742 - - - figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/04/04 2014/10/16 rogid:Gi0aAi/lO9gi5h6LMgke4advNsM559292 rogid:R6m5FOSsQ87OrJRnqo2hkjAtqkg559292 intact-crc:2C8083114249F009|rigid:fGIPEwnMjBuSO8ynM2u01ptfj6Q false alexa label:?-? alexa label:?-? 1 - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P32915 uniprotkb:P35179 intact:EBI-16400|ensemblfungi:YLR378C|uniprotkb:D6VZ14 intact:EBI-16406|ensemblfungi:YDR086C|uniprotkb:D6VS73 psi-mi:sc61a_yeast(display_long)|uniprotkb:Sec61 complex subunit SEC61(gene name synonym)|uniprotkb:L3502.5(orf name)|uniprotkb:YLR378C(locus name)|uniprotkb:SEC61(gene name)|psi-mi:SEC61(display_short)|uniprotkb:Sec61 complex subunit alpha(gene name synonym) psi-mi:sc61g_yeast(display_long)|uniprotkb:Sec61 complex subunit SSS1(gene name synonym)|uniprotkb:Ssh1 complex subunit SSS1(gene name synonym)|uniprotkb:D4475(orf name)|uniprotkb:YDR086C(locus name)|uniprotkb:SSS1(gene name)|psi-mi:SSS1(display_short)|uniprotkb:Sec61 complex subunit gamma(gene name synonym)|uniprotkb:Ssh1 complex subunit gamma(gene name synonym) psi-mi:"MI:0276"(blue native page) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9352403|imex:IM-22312-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0070843"(misfolded protein transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|go:"GO:0044743"(protein transmembrane import into intracellular organelle)|ensemblfungi:YLR378C(gene)|ensemblfungi:YLR378C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|refseq:NP_013482.1|sgd:S000004370|dip:DIP-2433N|mint:P32915 ensemblfungi:YDR086C(gene)|ensemblfungi:YDR086C_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0071261"(Ssh1 translocon complex)|interpro:IPR001901(Protein secE/sec61-gamma protein)|interpro:IPR008158(Protein translocase SEC61 complex gamma subunit)|interpro:IPR023391|rcsb pdb:2WW9|rcsb pdb:2WWA|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|reactome:R-SCE-9609523|refseq:NP_010371.1|sgd:S000002493|dip:DIP-2432N|mint:P35179 - - - figure legend:Fig. 4B, 4C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/04/04 2014/10/16 rogid:Gi0aAi/lO9gi5h6LMgke4advNsM559292 rogid:QIi5kN/8mDxTSvxRiJVi2JsPdws559292 intact-crc:3A573C44BFD1E579|rigid:z7rcGVfipHApPEJZlFfVPsORwG0 false flag tag:c-c flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P32915 uniprotkb:P52870 intact:EBI-16400|ensemblfungi:YLR378C|uniprotkb:D6VZ14 intact:EBI-16410|ensemblfungi:YER087C-B|uniprotkb:D3DLZ4 psi-mi:sc61a_yeast(display_long)|uniprotkb:Sec61 complex subunit SEC61(gene name synonym)|uniprotkb:L3502.5(orf name)|uniprotkb:YLR378C(locus name)|uniprotkb:SEC61(gene name)|psi-mi:SEC61(display_short)|uniprotkb:Sec61 complex subunit alpha(gene name synonym) psi-mi:sc6b1_yeast(display_long)|uniprotkb:Sec61 complex subunit SBH1(gene name synonym)|uniprotkb:YER087BC(orf name)|uniprotkb:YER087C-B(locus name)|uniprotkb:SBH1(gene name)|psi-mi:SBH1(display_short)|uniprotkb:SEB1(gene name synonym)|uniprotkb:Sec61 complex subunit beta(gene name synonym) psi-mi:"MI:0276"(blue native page) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9352403|imex:IM-22312-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0070843"(misfolded protein transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|go:"GO:0044743"(protein transmembrane import into intracellular organelle)|ensemblfungi:YLR378C(gene)|ensemblfungi:YLR378C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|refseq:NP_013482.1|sgd:S000004370|dip:DIP-2433N|mint:P32915 ensemblfungi:YER087C-B(gene)|ensemblfungi:YER087C-B_mRNA(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|interpro:IPR016482(Preprotein translocase Sec, Sec61-beta subunit, eukarya)|interpro:IPR030671|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|sgd:S000002128|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|refseq:NP_011011.3|dip:DIP-5681N|mint:P52870 - - - figure legend:Fig. 4B, 4C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/04/04 2014/10/16 rogid:Gi0aAi/lO9gi5h6LMgke4advNsM559292 rogid:9cYnDPhmMpAOdB2GV5TxikzpjI0559292 intact-crc:3A573C44BFD1E579|rigid:z7rcGVfipHApPEJZlFfVPsORwG0 false flag tag:c-c flag tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P14906 uniprotkb:P33754 intact:EBI-16636|uniprotkb:Q08690|ensemblfungi:YOR254C|uniprotkb:D6W2V5 intact:EBI-16647|ensemblfungi:YBR171W|uniprotkb:D6VQG7 psi-mi:sec63_yeast(display_long)|uniprotkb:PTL1(gene name synonym)|uniprotkb:YOR254C(locus name)|uniprotkb:SEC63(gene name)|psi-mi:SEC63(display_short)|uniprotkb:NPL1(gene name synonym)|uniprotkb:Sec62/63 complex 73 kDa subunit(gene name synonym)|uniprotkb:Protein NPL1(gene name synonym) psi-mi:sec66_yeast(display_long)|uniprotkb:SEC71(gene name synonym)|uniprotkb:YBR1232(orf name)|uniprotkb:YBR171W(locus name)|uniprotkb:SEC66(gene name)|psi-mi:SEC66(display_short)|uniprotkb:HSS1(gene name synonym)|uniprotkb:Sec62/63 complex 31.5 kDa subunit(gene name synonym)|uniprotkb:Protein HSS1(gene name synonym) psi-mi:"MI:0276"(blue native page) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9352414|imex:IM-22312-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YOR254C(gene)|ensemblfungi:YOR254C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|go:"GO:0046967"(cytosol to endoplasmic reticulum transport)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004179(Sec63)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR018253|interpro:IPR027137|interpro:IPR036869|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAI|rcsb pdb:7KAU|rcsb pdb:7KB5|refseq:NP_014897.1|sgd:S000005780|dip:DIP-2396N|mint:P14906 refseq:NP_009730.3|ensemblfungi:YBR171W(gene)|ensemblfungi:YBR171W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030447"(filamentous growth)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|go:"GO:0071944"(cell periphery)|interpro:IPR018624|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|sgd:S000000375|dip:DIP-1694N|mint:P33754 - - crc64:E2A8BB4994A227D4 figure legend:Fig. 4B, 4C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/04/04 2014/10/16 rogid:FcVMvm368fBcw0EH918+lqynntc559292 rogid:KvIn7euv+AwTIngwnUh/lmdLyaw559292 intact-crc:6F012609F77AFE2F|rigid:LgV7Dp2299O0lH5NBI3bKVdWAVk false flag tag:c-c flag tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P14906 uniprotkb:P39742 intact:EBI-16636|uniprotkb:Q08690|ensemblfungi:YOR254C|uniprotkb:D6W2V5 intact:EBI-16651|ensemblfungi:YLR292C|uniprotkb:D6VYT8 psi-mi:sec63_yeast(display_long)|uniprotkb:PTL1(gene name synonym)|uniprotkb:YOR254C(locus name)|uniprotkb:SEC63(gene name)|psi-mi:SEC63(display_short)|uniprotkb:NPL1(gene name synonym)|uniprotkb:Sec62/63 complex 73 kDa subunit(gene name synonym)|uniprotkb:Protein NPL1(gene name synonym) psi-mi:sec72_yeast(display_long)|uniprotkb:SEC67(gene name synonym)|uniprotkb:SIM2(gene name synonym)|uniprotkb:L8003.18(orf name)|uniprotkb:YLR292C(locus name)|uniprotkb:SEC72(gene name)|psi-mi:SEC72(display_short)|uniprotkb:Sec62/63 complex 23 kDa subunit(gene name synonym) psi-mi:"MI:0276"(blue native page) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9352414|imex:IM-22312-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YOR254C(gene)|ensemblfungi:YOR254C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|go:"GO:0046967"(cytosol to endoplasmic reticulum transport)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004179(Sec63)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR018253|interpro:IPR027137|interpro:IPR036869|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAI|rcsb pdb:7KAU|rcsb pdb:7KB5|refseq:NP_014897.1|sgd:S000005780|dip:DIP-2396N|mint:P14906 ensemblfungi:YLR292C(gene)|ensemblfungi:YLR292C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAJ|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|rcsb pdb:7KAO|rcsb pdb:7KAP|refseq:NP_013395.1|sgd:S000004283|dip:DIP-2491N|mint:P39742 - - - figure legend:Fig. 4B, 4C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/04/04 2014/10/16 rogid:FcVMvm368fBcw0EH918+lqynntc559292 rogid:R6m5FOSsQ87OrJRnqo2hkjAtqkg559292 intact-crc:6F012609F77AFE2F|rigid:LgV7Dp2299O0lH5NBI3bKVdWAVk false flag tag:c-c flag tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P21825 uniprotkb:P14906 intact:EBI-16632|ensemblfungi:YPL094C|uniprotkb:D6W3S3 intact:EBI-16636|uniprotkb:Q08690|ensemblfungi:YOR254C|uniprotkb:D6W2V5 psi-mi:sec62_yeast(display_long)|uniprotkb:SEC62(gene name)|psi-mi:SEC62(display_short)|uniprotkb:YPL094C(locus name)|uniprotkb:LPG14C(orf name)|uniprotkb:Sec62/63 complex 30 kDa subunit(gene name synonym) psi-mi:sec63_yeast(display_long)|uniprotkb:PTL1(gene name synonym)|uniprotkb:YOR254C(locus name)|uniprotkb:SEC63(gene name)|psi-mi:SEC63(display_short)|uniprotkb:NPL1(gene name synonym)|uniprotkb:Sec62/63 complex 73 kDa subunit(gene name synonym)|uniprotkb:Protein NPL1(gene name synonym) psi-mi:"MI:0276"(blue native page) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9352389|imex:IM-22312-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL094C(gene)|ensemblfungi:YPL094C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|interpro:IPR004728(Translocation protein Sec62)|interpro:IPR011553(Translocation protein Sec62, ascomycota)|rcsb pdb:6ZZZ|rcsb pdb:7AFT|refseq:NP_015231.2|sgd:S000006015|dip:DIP-3827N|mint:P21825 ensemblfungi:YOR254C(gene)|ensemblfungi:YOR254C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|go:"GO:0046967"(cytosol to endoplasmic reticulum transport)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004179(Sec63)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR018253|interpro:IPR027137|interpro:IPR036869|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAI|rcsb pdb:7KAU|rcsb pdb:7KB5|refseq:NP_014897.1|sgd:S000005780|dip:DIP-2396N|mint:P14906 - - - figure legend:Fig. 4B, 4C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/04/04 2014/10/16 rogid:ntcNjurhtyRtHO3uJOOcJXb2Meg559292 rogid:FcVMvm368fBcw0EH918+lqynntc559292 intact-crc:D165FF24109B19A6|rigid:tAck8kuVCMYyFA1Q4H1dISLS20Y false ha tag:c-c flag tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P21825 uniprotkb:P33754 intact:EBI-16632|ensemblfungi:YPL094C|uniprotkb:D6W3S3 intact:EBI-16647|ensemblfungi:YBR171W|uniprotkb:D6VQG7 psi-mi:sec62_yeast(display_long)|uniprotkb:SEC62(gene name)|psi-mi:SEC62(display_short)|uniprotkb:YPL094C(locus name)|uniprotkb:LPG14C(orf name)|uniprotkb:Sec62/63 complex 30 kDa subunit(gene name synonym) psi-mi:sec66_yeast(display_long)|uniprotkb:SEC71(gene name synonym)|uniprotkb:YBR1232(orf name)|uniprotkb:YBR171W(locus name)|uniprotkb:SEC66(gene name)|psi-mi:SEC66(display_short)|uniprotkb:HSS1(gene name synonym)|uniprotkb:Sec62/63 complex 31.5 kDa subunit(gene name synonym)|uniprotkb:Protein HSS1(gene name synonym) psi-mi:"MI:0276"(blue native page) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9352389|imex:IM-22312-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL094C(gene)|ensemblfungi:YPL094C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|interpro:IPR004728(Translocation protein Sec62)|interpro:IPR011553(Translocation protein Sec62, ascomycota)|rcsb pdb:6ZZZ|rcsb pdb:7AFT|refseq:NP_015231.2|sgd:S000006015|dip:DIP-3827N|mint:P21825 refseq:NP_009730.3|ensemblfungi:YBR171W(gene)|ensemblfungi:YBR171W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030447"(filamentous growth)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|go:"GO:0071944"(cell periphery)|interpro:IPR018624|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|sgd:S000000375|dip:DIP-1694N|mint:P33754 - - crc64:E2A8BB4994A227D4 figure legend:Fig. 4B, 4C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/04/04 2014/10/16 rogid:ntcNjurhtyRtHO3uJOOcJXb2Meg559292 rogid:KvIn7euv+AwTIngwnUh/lmdLyaw559292 intact-crc:D165FF24109B19A6|rigid:tAck8kuVCMYyFA1Q4H1dISLS20Y false ha tag:c-c flag tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P21825 uniprotkb:P39742 intact:EBI-16632|ensemblfungi:YPL094C|uniprotkb:D6W3S3 intact:EBI-16651|ensemblfungi:YLR292C|uniprotkb:D6VYT8 psi-mi:sec62_yeast(display_long)|uniprotkb:SEC62(gene name)|psi-mi:SEC62(display_short)|uniprotkb:YPL094C(locus name)|uniprotkb:LPG14C(orf name)|uniprotkb:Sec62/63 complex 30 kDa subunit(gene name synonym) psi-mi:sec72_yeast(display_long)|uniprotkb:SEC67(gene name synonym)|uniprotkb:SIM2(gene name synonym)|uniprotkb:L8003.18(orf name)|uniprotkb:YLR292C(locus name)|uniprotkb:SEC72(gene name)|psi-mi:SEC72(display_short)|uniprotkb:Sec62/63 complex 23 kDa subunit(gene name synonym) psi-mi:"MI:0276"(blue native page) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9352389|imex:IM-22312-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL094C(gene)|ensemblfungi:YPL094C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|interpro:IPR004728(Translocation protein Sec62)|interpro:IPR011553(Translocation protein Sec62, ascomycota)|rcsb pdb:6ZZZ|rcsb pdb:7AFT|refseq:NP_015231.2|sgd:S000006015|dip:DIP-3827N|mint:P21825 ensemblfungi:YLR292C(gene)|ensemblfungi:YLR292C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAJ|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|rcsb pdb:7KAO|rcsb pdb:7KAP|refseq:NP_013395.1|sgd:S000004283|dip:DIP-2491N|mint:P39742 - - - figure legend:Fig. 4B, 4C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/04/04 2014/10/16 rogid:ntcNjurhtyRtHO3uJOOcJXb2Meg559292 rogid:R6m5FOSsQ87OrJRnqo2hkjAtqkg559292 intact-crc:D165FF24109B19A6|rigid:tAck8kuVCMYyFA1Q4H1dISLS20Y false ha tag:c-c flag tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P32915 uniprotkb:P35179 intact:EBI-16400|ensemblfungi:YLR378C|uniprotkb:D6VZ14 intact:EBI-16406|ensemblfungi:YDR086C|uniprotkb:D6VS73 psi-mi:sc61a_yeast(display_long)|uniprotkb:Sec61 complex subunit SEC61(gene name synonym)|uniprotkb:L3502.5(orf name)|uniprotkb:YLR378C(locus name)|uniprotkb:SEC61(gene name)|psi-mi:SEC61(display_short)|uniprotkb:Sec61 complex subunit alpha(gene name synonym) psi-mi:sc61g_yeast(display_long)|uniprotkb:Sec61 complex subunit SSS1(gene name synonym)|uniprotkb:Ssh1 complex subunit SSS1(gene name synonym)|uniprotkb:D4475(orf name)|uniprotkb:YDR086C(locus name)|uniprotkb:SSS1(gene name)|psi-mi:SSS1(display_short)|uniprotkb:Sec61 complex subunit gamma(gene name synonym)|uniprotkb:Ssh1 complex subunit gamma(gene name synonym) psi-mi:"MI:0276"(blue native page) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9352366|imex:IM-22312-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0070843"(misfolded protein transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|go:"GO:0044743"(protein transmembrane import into intracellular organelle)|ensemblfungi:YLR378C(gene)|ensemblfungi:YLR378C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|refseq:NP_013482.1|sgd:S000004370|dip:DIP-2433N|mint:P32915 ensemblfungi:YDR086C(gene)|ensemblfungi:YDR086C_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0071261"(Ssh1 translocon complex)|interpro:IPR001901(Protein secE/sec61-gamma protein)|interpro:IPR008158(Protein translocase SEC61 complex gamma subunit)|interpro:IPR023391|rcsb pdb:2WW9|rcsb pdb:2WWA|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|reactome:R-SCE-9609523|refseq:NP_010371.1|sgd:S000002493|dip:DIP-2432N|mint:P35179 - - - figure legend:Fig. 4B, 4C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/04/04 2014/10/16 rogid:Gi0aAi/lO9gi5h6LMgke4advNsM559292 rogid:QIi5kN/8mDxTSvxRiJVi2JsPdws559292 intact-crc:BCB0432FB03D5C3E|rigid:kl5v5RIqDGmk3pgYMBGmh+Dohag false flag tag:c-c flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P32915 uniprotkb:P52870 intact:EBI-16400|ensemblfungi:YLR378C|uniprotkb:D6VZ14 intact:EBI-16410|ensemblfungi:YER087C-B|uniprotkb:D3DLZ4 psi-mi:sc61a_yeast(display_long)|uniprotkb:Sec61 complex subunit SEC61(gene name synonym)|uniprotkb:L3502.5(orf name)|uniprotkb:YLR378C(locus name)|uniprotkb:SEC61(gene name)|psi-mi:SEC61(display_short)|uniprotkb:Sec61 complex subunit alpha(gene name synonym) psi-mi:sc6b1_yeast(display_long)|uniprotkb:Sec61 complex subunit SBH1(gene name synonym)|uniprotkb:YER087BC(orf name)|uniprotkb:YER087C-B(locus name)|uniprotkb:SBH1(gene name)|psi-mi:SBH1(display_short)|uniprotkb:SEB1(gene name synonym)|uniprotkb:Sec61 complex subunit beta(gene name synonym) psi-mi:"MI:0276"(blue native page) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9352366|imex:IM-22312-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0070843"(misfolded protein transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|go:"GO:0044743"(protein transmembrane import into intracellular organelle)|ensemblfungi:YLR378C(gene)|ensemblfungi:YLR378C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|refseq:NP_013482.1|sgd:S000004370|dip:DIP-2433N|mint:P32915 ensemblfungi:YER087C-B(gene)|ensemblfungi:YER087C-B_mRNA(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|interpro:IPR016482(Preprotein translocase Sec, Sec61-beta subunit, eukarya)|interpro:IPR030671|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|sgd:S000002128|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|refseq:NP_011011.3|dip:DIP-5681N|mint:P52870 - - - figure legend:Fig. 4B, 4C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/04/04 2014/10/16 rogid:Gi0aAi/lO9gi5h6LMgke4advNsM559292 rogid:9cYnDPhmMpAOdB2GV5TxikzpjI0559292 intact-crc:BCB0432FB03D5C3E|rigid:kl5v5RIqDGmk3pgYMBGmh+Dohag false flag tag:c-c flag tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P32915 uniprotkb:P21825 intact:EBI-16400|ensemblfungi:YLR378C|uniprotkb:D6VZ14 intact:EBI-16632|ensemblfungi:YPL094C|uniprotkb:D6W3S3 psi-mi:sc61a_yeast(display_long)|uniprotkb:Sec61 complex subunit SEC61(gene name synonym)|uniprotkb:L3502.5(orf name)|uniprotkb:YLR378C(locus name)|uniprotkb:SEC61(gene name)|psi-mi:SEC61(display_short)|uniprotkb:Sec61 complex subunit alpha(gene name synonym) psi-mi:sec62_yeast(display_long)|uniprotkb:SEC62(gene name)|psi-mi:SEC62(display_short)|uniprotkb:YPL094C(locus name)|uniprotkb:LPG14C(orf name)|uniprotkb:Sec62/63 complex 30 kDa subunit(gene name synonym) psi-mi:"MI:0276"(blue native page) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9352366|imex:IM-22312-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0070843"(misfolded protein transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|go:"GO:0044743"(protein transmembrane import into intracellular organelle)|ensemblfungi:YLR378C(gene)|ensemblfungi:YLR378C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|refseq:NP_013482.1|sgd:S000004370|dip:DIP-2433N|mint:P32915 ensemblfungi:YPL094C(gene)|ensemblfungi:YPL094C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|interpro:IPR004728(Translocation protein Sec62)|interpro:IPR011553(Translocation protein Sec62, ascomycota)|rcsb pdb:6ZZZ|rcsb pdb:7AFT|refseq:NP_015231.2|sgd:S000006015|dip:DIP-3827N|mint:P21825 - - - figure legend:Fig. 4B, 4C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/04/04 2014/10/16 rogid:Gi0aAi/lO9gi5h6LMgke4advNsM559292 rogid:ntcNjurhtyRtHO3uJOOcJXb2Meg559292 intact-crc:BCB0432FB03D5C3E|rigid:kl5v5RIqDGmk3pgYMBGmh+Dohag false flag tag:c-c ha tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P32915 uniprotkb:P14906 intact:EBI-16400|ensemblfungi:YLR378C|uniprotkb:D6VZ14 intact:EBI-16636|uniprotkb:Q08690|ensemblfungi:YOR254C|uniprotkb:D6W2V5 psi-mi:sc61a_yeast(display_long)|uniprotkb:Sec61 complex subunit SEC61(gene name synonym)|uniprotkb:L3502.5(orf name)|uniprotkb:YLR378C(locus name)|uniprotkb:SEC61(gene name)|psi-mi:SEC61(display_short)|uniprotkb:Sec61 complex subunit alpha(gene name synonym) psi-mi:sec63_yeast(display_long)|uniprotkb:PTL1(gene name synonym)|uniprotkb:YOR254C(locus name)|uniprotkb:SEC63(gene name)|psi-mi:SEC63(display_short)|uniprotkb:NPL1(gene name synonym)|uniprotkb:Sec62/63 complex 73 kDa subunit(gene name synonym)|uniprotkb:Protein NPL1(gene name synonym) psi-mi:"MI:0276"(blue native page) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9352366|imex:IM-22312-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0070843"(misfolded protein transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|go:"GO:0044743"(protein transmembrane import into intracellular organelle)|ensemblfungi:YLR378C(gene)|ensemblfungi:YLR378C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|refseq:NP_013482.1|sgd:S000004370|dip:DIP-2433N|mint:P32915 ensemblfungi:YOR254C(gene)|ensemblfungi:YOR254C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|go:"GO:0046967"(cytosol to endoplasmic reticulum transport)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004179(Sec63)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR018253|interpro:IPR027137|interpro:IPR036869|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAI|rcsb pdb:7KAU|rcsb pdb:7KB5|refseq:NP_014897.1|sgd:S000005780|dip:DIP-2396N|mint:P14906 - - - figure legend:Fig. 4B, 4C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/04/04 2014/10/16 rogid:Gi0aAi/lO9gi5h6LMgke4advNsM559292 rogid:FcVMvm368fBcw0EH918+lqynntc559292 intact-crc:BCB0432FB03D5C3E|rigid:kl5v5RIqDGmk3pgYMBGmh+Dohag false flag tag:c-c flag tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P32915 uniprotkb:P33754 intact:EBI-16400|ensemblfungi:YLR378C|uniprotkb:D6VZ14 intact:EBI-16647|ensemblfungi:YBR171W|uniprotkb:D6VQG7 psi-mi:sc61a_yeast(display_long)|uniprotkb:Sec61 complex subunit SEC61(gene name synonym)|uniprotkb:L3502.5(orf name)|uniprotkb:YLR378C(locus name)|uniprotkb:SEC61(gene name)|psi-mi:SEC61(display_short)|uniprotkb:Sec61 complex subunit alpha(gene name synonym) psi-mi:sec66_yeast(display_long)|uniprotkb:SEC71(gene name synonym)|uniprotkb:YBR1232(orf name)|uniprotkb:YBR171W(locus name)|uniprotkb:SEC66(gene name)|psi-mi:SEC66(display_short)|uniprotkb:HSS1(gene name synonym)|uniprotkb:Sec62/63 complex 31.5 kDa subunit(gene name synonym)|uniprotkb:Protein HSS1(gene name synonym) psi-mi:"MI:0276"(blue native page) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9352366|imex:IM-22312-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0070843"(misfolded protein transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|go:"GO:0044743"(protein transmembrane import into intracellular organelle)|ensemblfungi:YLR378C(gene)|ensemblfungi:YLR378C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|refseq:NP_013482.1|sgd:S000004370|dip:DIP-2433N|mint:P32915 refseq:NP_009730.3|ensemblfungi:YBR171W(gene)|ensemblfungi:YBR171W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030447"(filamentous growth)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|go:"GO:0071944"(cell periphery)|interpro:IPR018624|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|sgd:S000000375|dip:DIP-1694N|mint:P33754 - - crc64:E2A8BB4994A227D4 figure legend:Fig. 4B, 4C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/04/04 2014/10/16 rogid:Gi0aAi/lO9gi5h6LMgke4advNsM559292 rogid:KvIn7euv+AwTIngwnUh/lmdLyaw559292 intact-crc:BCB0432FB03D5C3E|rigid:kl5v5RIqDGmk3pgYMBGmh+Dohag false flag tag:c-c flag tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P32915 uniprotkb:P39742 intact:EBI-16400|ensemblfungi:YLR378C|uniprotkb:D6VZ14 intact:EBI-16651|ensemblfungi:YLR292C|uniprotkb:D6VYT8 psi-mi:sc61a_yeast(display_long)|uniprotkb:Sec61 complex subunit SEC61(gene name synonym)|uniprotkb:L3502.5(orf name)|uniprotkb:YLR378C(locus name)|uniprotkb:SEC61(gene name)|psi-mi:SEC61(display_short)|uniprotkb:Sec61 complex subunit alpha(gene name synonym) psi-mi:sec72_yeast(display_long)|uniprotkb:SEC67(gene name synonym)|uniprotkb:SIM2(gene name synonym)|uniprotkb:L8003.18(orf name)|uniprotkb:YLR292C(locus name)|uniprotkb:SEC72(gene name)|psi-mi:SEC72(display_short)|uniprotkb:Sec62/63 complex 23 kDa subunit(gene name synonym) psi-mi:"MI:0276"(blue native page) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9352366|imex:IM-22312-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0070843"(misfolded protein transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|go:"GO:0044743"(protein transmembrane import into intracellular organelle)|ensemblfungi:YLR378C(gene)|ensemblfungi:YLR378C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|refseq:NP_013482.1|sgd:S000004370|dip:DIP-2433N|mint:P32915 ensemblfungi:YLR292C(gene)|ensemblfungi:YLR292C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAJ|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|rcsb pdb:7KAO|rcsb pdb:7KAP|refseq:NP_013395.1|sgd:S000004283|dip:DIP-2491N|mint:P39742 - - - figure legend:Fig. 4B, 4C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/04/04 2014/10/16 rogid:Gi0aAi/lO9gi5h6LMgke4advNsM559292 rogid:R6m5FOSsQ87OrJRnqo2hkjAtqkg559292 intact-crc:BCB0432FB03D5C3E|rigid:kl5v5RIqDGmk3pgYMBGmh+Dohag false flag tag:c-c flag tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P32915 uniprotkb:P35179 intact:EBI-16400|ensemblfungi:YLR378C|uniprotkb:D6VZ14 intact:EBI-16406|ensemblfungi:YDR086C|uniprotkb:D6VS73 psi-mi:sc61a_yeast(display_long)|uniprotkb:Sec61 complex subunit SEC61(gene name synonym)|uniprotkb:L3502.5(orf name)|uniprotkb:YLR378C(locus name)|uniprotkb:SEC61(gene name)|psi-mi:SEC61(display_short)|uniprotkb:Sec61 complex subunit alpha(gene name synonym) psi-mi:sc61g_yeast(display_long)|uniprotkb:Sec61 complex subunit SSS1(gene name synonym)|uniprotkb:Ssh1 complex subunit SSS1(gene name synonym)|uniprotkb:D4475(orf name)|uniprotkb:YDR086C(locus name)|uniprotkb:SSS1(gene name)|psi-mi:SSS1(display_short)|uniprotkb:Sec61 complex subunit gamma(gene name synonym)|uniprotkb:Ssh1 complex subunit gamma(gene name synonym) psi-mi:"MI:0040"(electron microscopy) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9354373|imex:IM-22312-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0070843"(misfolded protein transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|go:"GO:0044743"(protein transmembrane import into intracellular organelle)|ensemblfungi:YLR378C(gene)|ensemblfungi:YLR378C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|refseq:NP_013482.1|sgd:S000004370|dip:DIP-2433N|mint:P32915 ensemblfungi:YDR086C(gene)|ensemblfungi:YDR086C_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0071261"(Ssh1 translocon complex)|interpro:IPR001901(Protein secE/sec61-gamma protein)|interpro:IPR008158(Protein translocase SEC61 complex gamma subunit)|interpro:IPR023391|rcsb pdb:2WW9|rcsb pdb:2WWA|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|reactome:R-SCE-9609523|refseq:NP_010371.1|sgd:S000002493|dip:DIP-2432N|mint:P35179 - - - figure legend:Fig. 6B|comment:Complex mass 287 kDa, standard deviation = 42 kDa|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/04 2014/10/16 rogid:Gi0aAi/lO9gi5h6LMgke4advNsM559292 rogid:QIi5kN/8mDxTSvxRiJVi2JsPdws559292 intact-crc:D06219758BA419FD|rigid:kl5v5RIqDGmk3pgYMBGmh+Dohag false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32915 uniprotkb:P52870 intact:EBI-16400|ensemblfungi:YLR378C|uniprotkb:D6VZ14 intact:EBI-16410|ensemblfungi:YER087C-B|uniprotkb:D3DLZ4 psi-mi:sc61a_yeast(display_long)|uniprotkb:Sec61 complex subunit SEC61(gene name synonym)|uniprotkb:L3502.5(orf name)|uniprotkb:YLR378C(locus name)|uniprotkb:SEC61(gene name)|psi-mi:SEC61(display_short)|uniprotkb:Sec61 complex subunit alpha(gene name synonym) psi-mi:sc6b1_yeast(display_long)|uniprotkb:Sec61 complex subunit SBH1(gene name synonym)|uniprotkb:YER087BC(orf name)|uniprotkb:YER087C-B(locus name)|uniprotkb:SBH1(gene name)|psi-mi:SBH1(display_short)|uniprotkb:SEB1(gene name synonym)|uniprotkb:Sec61 complex subunit beta(gene name synonym) psi-mi:"MI:0040"(electron microscopy) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9354373|imex:IM-22312-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0070843"(misfolded protein transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|go:"GO:0044743"(protein transmembrane import into intracellular organelle)|ensemblfungi:YLR378C(gene)|ensemblfungi:YLR378C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|refseq:NP_013482.1|sgd:S000004370|dip:DIP-2433N|mint:P32915 ensemblfungi:YER087C-B(gene)|ensemblfungi:YER087C-B_mRNA(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|interpro:IPR016482(Preprotein translocase Sec, Sec61-beta subunit, eukarya)|interpro:IPR030671|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|sgd:S000002128|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|refseq:NP_011011.3|dip:DIP-5681N|mint:P52870 - - - figure legend:Fig. 6B|comment:Complex mass 287 kDa, standard deviation = 42 kDa|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/04 2014/10/16 rogid:Gi0aAi/lO9gi5h6LMgke4advNsM559292 rogid:9cYnDPhmMpAOdB2GV5TxikzpjI0559292 intact-crc:D06219758BA419FD|rigid:kl5v5RIqDGmk3pgYMBGmh+Dohag false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32915 uniprotkb:P21825 intact:EBI-16400|ensemblfungi:YLR378C|uniprotkb:D6VZ14 intact:EBI-16632|ensemblfungi:YPL094C|uniprotkb:D6W3S3 psi-mi:sc61a_yeast(display_long)|uniprotkb:Sec61 complex subunit SEC61(gene name synonym)|uniprotkb:L3502.5(orf name)|uniprotkb:YLR378C(locus name)|uniprotkb:SEC61(gene name)|psi-mi:SEC61(display_short)|uniprotkb:Sec61 complex subunit alpha(gene name synonym) psi-mi:sec62_yeast(display_long)|uniprotkb:SEC62(gene name)|psi-mi:SEC62(display_short)|uniprotkb:YPL094C(locus name)|uniprotkb:LPG14C(orf name)|uniprotkb:Sec62/63 complex 30 kDa subunit(gene name synonym) psi-mi:"MI:0040"(electron microscopy) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9354373|imex:IM-22312-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0070843"(misfolded protein transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|go:"GO:0044743"(protein transmembrane import into intracellular organelle)|ensemblfungi:YLR378C(gene)|ensemblfungi:YLR378C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|refseq:NP_013482.1|sgd:S000004370|dip:DIP-2433N|mint:P32915 ensemblfungi:YPL094C(gene)|ensemblfungi:YPL094C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|interpro:IPR004728(Translocation protein Sec62)|interpro:IPR011553(Translocation protein Sec62, ascomycota)|rcsb pdb:6ZZZ|rcsb pdb:7AFT|refseq:NP_015231.2|sgd:S000006015|dip:DIP-3827N|mint:P21825 - - - figure legend:Fig. 6B|comment:Complex mass 287 kDa, standard deviation = 42 kDa|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/04 2014/10/16 rogid:Gi0aAi/lO9gi5h6LMgke4advNsM559292 rogid:ntcNjurhtyRtHO3uJOOcJXb2Meg559292 intact-crc:D06219758BA419FD|rigid:kl5v5RIqDGmk3pgYMBGmh+Dohag false - ha tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32915 uniprotkb:P14906 intact:EBI-16400|ensemblfungi:YLR378C|uniprotkb:D6VZ14 intact:EBI-16636|uniprotkb:Q08690|ensemblfungi:YOR254C|uniprotkb:D6W2V5 psi-mi:sc61a_yeast(display_long)|uniprotkb:Sec61 complex subunit SEC61(gene name synonym)|uniprotkb:L3502.5(orf name)|uniprotkb:YLR378C(locus name)|uniprotkb:SEC61(gene name)|psi-mi:SEC61(display_short)|uniprotkb:Sec61 complex subunit alpha(gene name synonym) psi-mi:sec63_yeast(display_long)|uniprotkb:PTL1(gene name synonym)|uniprotkb:YOR254C(locus name)|uniprotkb:SEC63(gene name)|psi-mi:SEC63(display_short)|uniprotkb:NPL1(gene name synonym)|uniprotkb:Sec62/63 complex 73 kDa subunit(gene name synonym)|uniprotkb:Protein NPL1(gene name synonym) psi-mi:"MI:0040"(electron microscopy) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9354373|imex:IM-22312-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0070843"(misfolded protein transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|go:"GO:0044743"(protein transmembrane import into intracellular organelle)|ensemblfungi:YLR378C(gene)|ensemblfungi:YLR378C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|refseq:NP_013482.1|sgd:S000004370|dip:DIP-2433N|mint:P32915 ensemblfungi:YOR254C(gene)|ensemblfungi:YOR254C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|go:"GO:0046967"(cytosol to endoplasmic reticulum transport)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004179(Sec63)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR018253|interpro:IPR027137|interpro:IPR036869|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAI|rcsb pdb:7KAU|rcsb pdb:7KB5|refseq:NP_014897.1|sgd:S000005780|dip:DIP-2396N|mint:P14906 - - - figure legend:Fig. 6B|comment:Complex mass 287 kDa, standard deviation = 42 kDa|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/04 2014/10/16 rogid:Gi0aAi/lO9gi5h6LMgke4advNsM559292 rogid:FcVMvm368fBcw0EH918+lqynntc559292 intact-crc:D06219758BA419FD|rigid:kl5v5RIqDGmk3pgYMBGmh+Dohag false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32915 uniprotkb:P33754 intact:EBI-16400|ensemblfungi:YLR378C|uniprotkb:D6VZ14 intact:EBI-16647|ensemblfungi:YBR171W|uniprotkb:D6VQG7 psi-mi:sc61a_yeast(display_long)|uniprotkb:Sec61 complex subunit SEC61(gene name synonym)|uniprotkb:L3502.5(orf name)|uniprotkb:YLR378C(locus name)|uniprotkb:SEC61(gene name)|psi-mi:SEC61(display_short)|uniprotkb:Sec61 complex subunit alpha(gene name synonym) psi-mi:sec66_yeast(display_long)|uniprotkb:SEC71(gene name synonym)|uniprotkb:YBR1232(orf name)|uniprotkb:YBR171W(locus name)|uniprotkb:SEC66(gene name)|psi-mi:SEC66(display_short)|uniprotkb:HSS1(gene name synonym)|uniprotkb:Sec62/63 complex 31.5 kDa subunit(gene name synonym)|uniprotkb:Protein HSS1(gene name synonym) psi-mi:"MI:0040"(electron microscopy) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9354373|imex:IM-22312-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0070843"(misfolded protein transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|go:"GO:0044743"(protein transmembrane import into intracellular organelle)|ensemblfungi:YLR378C(gene)|ensemblfungi:YLR378C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|refseq:NP_013482.1|sgd:S000004370|dip:DIP-2433N|mint:P32915 refseq:NP_009730.3|ensemblfungi:YBR171W(gene)|ensemblfungi:YBR171W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030447"(filamentous growth)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|go:"GO:0071944"(cell periphery)|interpro:IPR018624|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|sgd:S000000375|dip:DIP-1694N|mint:P33754 - - crc64:E2A8BB4994A227D4 figure legend:Fig. 6B|comment:Complex mass 287 kDa, standard deviation = 42 kDa|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/04 2014/10/16 rogid:Gi0aAi/lO9gi5h6LMgke4advNsM559292 rogid:KvIn7euv+AwTIngwnUh/lmdLyaw559292 intact-crc:D06219758BA419FD|rigid:kl5v5RIqDGmk3pgYMBGmh+Dohag false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32915 uniprotkb:P39742 intact:EBI-16400|ensemblfungi:YLR378C|uniprotkb:D6VZ14 intact:EBI-16651|ensemblfungi:YLR292C|uniprotkb:D6VYT8 psi-mi:sc61a_yeast(display_long)|uniprotkb:Sec61 complex subunit SEC61(gene name synonym)|uniprotkb:L3502.5(orf name)|uniprotkb:YLR378C(locus name)|uniprotkb:SEC61(gene name)|psi-mi:SEC61(display_short)|uniprotkb:Sec61 complex subunit alpha(gene name synonym) psi-mi:sec72_yeast(display_long)|uniprotkb:SEC67(gene name synonym)|uniprotkb:SIM2(gene name synonym)|uniprotkb:L8003.18(orf name)|uniprotkb:YLR292C(locus name)|uniprotkb:SEC72(gene name)|psi-mi:SEC72(display_short)|uniprotkb:Sec62/63 complex 23 kDa subunit(gene name synonym) psi-mi:"MI:0040"(electron microscopy) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9354373|imex:IM-22312-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0070843"(misfolded protein transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|go:"GO:0044743"(protein transmembrane import into intracellular organelle)|ensemblfungi:YLR378C(gene)|ensemblfungi:YLR378C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|refseq:NP_013482.1|sgd:S000004370|dip:DIP-2433N|mint:P32915 ensemblfungi:YLR292C(gene)|ensemblfungi:YLR292C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAJ|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|rcsb pdb:7KAO|rcsb pdb:7KAP|refseq:NP_013395.1|sgd:S000004283|dip:DIP-2491N|mint:P39742 - - - figure legend:Fig. 6B|comment:Complex mass 287 kDa, standard deviation = 42 kDa|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/04 2014/10/16 rogid:Gi0aAi/lO9gi5h6LMgke4advNsM559292 rogid:R6m5FOSsQ87OrJRnqo2hkjAtqkg559292 intact-crc:D06219758BA419FD|rigid:kl5v5RIqDGmk3pgYMBGmh+Dohag false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32915 uniprotkb:P35179 intact:EBI-16400|ensemblfungi:YLR378C|uniprotkb:D6VZ14 intact:EBI-16406|ensemblfungi:YDR086C|uniprotkb:D6VS73 psi-mi:sc61a_yeast(display_long)|uniprotkb:Sec61 complex subunit SEC61(gene name synonym)|uniprotkb:L3502.5(orf name)|uniprotkb:YLR378C(locus name)|uniprotkb:SEC61(gene name)|psi-mi:SEC61(display_short)|uniprotkb:Sec61 complex subunit alpha(gene name synonym) psi-mi:sc61g_yeast(display_long)|uniprotkb:Sec61 complex subunit SSS1(gene name synonym)|uniprotkb:Ssh1 complex subunit SSS1(gene name synonym)|uniprotkb:D4475(orf name)|uniprotkb:YDR086C(locus name)|uniprotkb:SSS1(gene name)|psi-mi:SSS1(display_short)|uniprotkb:Sec61 complex subunit gamma(gene name synonym)|uniprotkb:Ssh1 complex subunit gamma(gene name synonym) psi-mi:"MI:0040"(electron microscopy) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9354392|imex:IM-22312-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0070843"(misfolded protein transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|go:"GO:0044743"(protein transmembrane import into intracellular organelle)|ensemblfungi:YLR378C(gene)|ensemblfungi:YLR378C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|refseq:NP_013482.1|sgd:S000004370|dip:DIP-2433N|mint:P32915 ensemblfungi:YDR086C(gene)|ensemblfungi:YDR086C_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0071261"(Ssh1 translocon complex)|interpro:IPR001901(Protein secE/sec61-gamma protein)|interpro:IPR008158(Protein translocase SEC61 complex gamma subunit)|interpro:IPR023391|rcsb pdb:2WW9|rcsb pdb:2WWA|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|reactome:R-SCE-9609523|refseq:NP_010371.1|sgd:S000002493|dip:DIP-2432N|mint:P35179 - - - figure legend:"Fig. 6B (lower panel), 7A"|comment:Complex mass 287 kDa, standard deviation = 42 kDa|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/04 2014/10/16 rogid:Gi0aAi/lO9gi5h6LMgke4advNsM559292 rogid:QIi5kN/8mDxTSvxRiJVi2JsPdws559292 intact-crc:AFDA719E2532AAFF|rigid:kl5v5RIqDGmk3pgYMBGmh+Dohag false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32915 uniprotkb:P52870 intact:EBI-16400|ensemblfungi:YLR378C|uniprotkb:D6VZ14 intact:EBI-16410|ensemblfungi:YER087C-B|uniprotkb:D3DLZ4 psi-mi:sc61a_yeast(display_long)|uniprotkb:Sec61 complex subunit SEC61(gene name synonym)|uniprotkb:L3502.5(orf name)|uniprotkb:YLR378C(locus name)|uniprotkb:SEC61(gene name)|psi-mi:SEC61(display_short)|uniprotkb:Sec61 complex subunit alpha(gene name synonym) psi-mi:sc6b1_yeast(display_long)|uniprotkb:Sec61 complex subunit SBH1(gene name synonym)|uniprotkb:YER087BC(orf name)|uniprotkb:YER087C-B(locus name)|uniprotkb:SBH1(gene name)|psi-mi:SBH1(display_short)|uniprotkb:SEB1(gene name synonym)|uniprotkb:Sec61 complex subunit beta(gene name synonym) psi-mi:"MI:0040"(electron microscopy) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9354392|imex:IM-22312-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0070843"(misfolded protein transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|go:"GO:0044743"(protein transmembrane import into intracellular organelle)|ensemblfungi:YLR378C(gene)|ensemblfungi:YLR378C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|refseq:NP_013482.1|sgd:S000004370|dip:DIP-2433N|mint:P32915 ensemblfungi:YER087C-B(gene)|ensemblfungi:YER087C-B_mRNA(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|interpro:IPR016482(Preprotein translocase Sec, Sec61-beta subunit, eukarya)|interpro:IPR030671|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|sgd:S000002128|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|refseq:NP_011011.3|dip:DIP-5681N|mint:P52870 - - - figure legend:"Fig. 6B (lower panel), 7A"|comment:Complex mass 287 kDa, standard deviation = 42 kDa|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/04 2014/10/16 rogid:Gi0aAi/lO9gi5h6LMgke4advNsM559292 rogid:9cYnDPhmMpAOdB2GV5TxikzpjI0559292 intact-crc:AFDA719E2532AAFF|rigid:kl5v5RIqDGmk3pgYMBGmh+Dohag false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32915 uniprotkb:P21825 intact:EBI-16400|ensemblfungi:YLR378C|uniprotkb:D6VZ14 intact:EBI-16632|ensemblfungi:YPL094C|uniprotkb:D6W3S3 psi-mi:sc61a_yeast(display_long)|uniprotkb:Sec61 complex subunit SEC61(gene name synonym)|uniprotkb:L3502.5(orf name)|uniprotkb:YLR378C(locus name)|uniprotkb:SEC61(gene name)|psi-mi:SEC61(display_short)|uniprotkb:Sec61 complex subunit alpha(gene name synonym) psi-mi:sec62_yeast(display_long)|uniprotkb:SEC62(gene name)|psi-mi:SEC62(display_short)|uniprotkb:YPL094C(locus name)|uniprotkb:LPG14C(orf name)|uniprotkb:Sec62/63 complex 30 kDa subunit(gene name synonym) psi-mi:"MI:0040"(electron microscopy) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9354392|imex:IM-22312-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0070843"(misfolded protein transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|go:"GO:0044743"(protein transmembrane import into intracellular organelle)|ensemblfungi:YLR378C(gene)|ensemblfungi:YLR378C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|refseq:NP_013482.1|sgd:S000004370|dip:DIP-2433N|mint:P32915 ensemblfungi:YPL094C(gene)|ensemblfungi:YPL094C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|interpro:IPR004728(Translocation protein Sec62)|interpro:IPR011553(Translocation protein Sec62, ascomycota)|rcsb pdb:6ZZZ|rcsb pdb:7AFT|refseq:NP_015231.2|sgd:S000006015|dip:DIP-3827N|mint:P21825 - - - figure legend:"Fig. 6B (lower panel), 7A"|comment:Complex mass 287 kDa, standard deviation = 42 kDa|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/04 2014/10/16 rogid:Gi0aAi/lO9gi5h6LMgke4advNsM559292 rogid:ntcNjurhtyRtHO3uJOOcJXb2Meg559292 intact-crc:AFDA719E2532AAFF|rigid:kl5v5RIqDGmk3pgYMBGmh+Dohag false - ha tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32915 uniprotkb:P14906 intact:EBI-16400|ensemblfungi:YLR378C|uniprotkb:D6VZ14 intact:EBI-16636|uniprotkb:Q08690|ensemblfungi:YOR254C|uniprotkb:D6W2V5 psi-mi:sc61a_yeast(display_long)|uniprotkb:Sec61 complex subunit SEC61(gene name synonym)|uniprotkb:L3502.5(orf name)|uniprotkb:YLR378C(locus name)|uniprotkb:SEC61(gene name)|psi-mi:SEC61(display_short)|uniprotkb:Sec61 complex subunit alpha(gene name synonym) psi-mi:sec63_yeast(display_long)|uniprotkb:PTL1(gene name synonym)|uniprotkb:YOR254C(locus name)|uniprotkb:SEC63(gene name)|psi-mi:SEC63(display_short)|uniprotkb:NPL1(gene name synonym)|uniprotkb:Sec62/63 complex 73 kDa subunit(gene name synonym)|uniprotkb:Protein NPL1(gene name synonym) psi-mi:"MI:0040"(electron microscopy) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9354392|imex:IM-22312-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0070843"(misfolded protein transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|go:"GO:0044743"(protein transmembrane import into intracellular organelle)|ensemblfungi:YLR378C(gene)|ensemblfungi:YLR378C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|refseq:NP_013482.1|sgd:S000004370|dip:DIP-2433N|mint:P32915 ensemblfungi:YOR254C(gene)|ensemblfungi:YOR254C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|go:"GO:0046967"(cytosol to endoplasmic reticulum transport)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004179(Sec63)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR018253|interpro:IPR027137|interpro:IPR036869|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAI|rcsb pdb:7KAU|rcsb pdb:7KB5|refseq:NP_014897.1|sgd:S000005780|dip:DIP-2396N|mint:P14906 - - - figure legend:"Fig. 6B (lower panel), 7A"|comment:Complex mass 287 kDa, standard deviation = 42 kDa|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/04 2014/10/16 rogid:Gi0aAi/lO9gi5h6LMgke4advNsM559292 rogid:FcVMvm368fBcw0EH918+lqynntc559292 intact-crc:AFDA719E2532AAFF|rigid:kl5v5RIqDGmk3pgYMBGmh+Dohag false - maltose binding protein tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32915 uniprotkb:P33754 intact:EBI-16400|ensemblfungi:YLR378C|uniprotkb:D6VZ14 intact:EBI-16647|ensemblfungi:YBR171W|uniprotkb:D6VQG7 psi-mi:sc61a_yeast(display_long)|uniprotkb:Sec61 complex subunit SEC61(gene name synonym)|uniprotkb:L3502.5(orf name)|uniprotkb:YLR378C(locus name)|uniprotkb:SEC61(gene name)|psi-mi:SEC61(display_short)|uniprotkb:Sec61 complex subunit alpha(gene name synonym) psi-mi:sec66_yeast(display_long)|uniprotkb:SEC71(gene name synonym)|uniprotkb:YBR1232(orf name)|uniprotkb:YBR171W(locus name)|uniprotkb:SEC66(gene name)|psi-mi:SEC66(display_short)|uniprotkb:HSS1(gene name synonym)|uniprotkb:Sec62/63 complex 31.5 kDa subunit(gene name synonym)|uniprotkb:Protein HSS1(gene name synonym) psi-mi:"MI:0040"(electron microscopy) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9354392|imex:IM-22312-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0070843"(misfolded protein transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|go:"GO:0044743"(protein transmembrane import into intracellular organelle)|ensemblfungi:YLR378C(gene)|ensemblfungi:YLR378C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|refseq:NP_013482.1|sgd:S000004370|dip:DIP-2433N|mint:P32915 refseq:NP_009730.3|ensemblfungi:YBR171W(gene)|ensemblfungi:YBR171W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030447"(filamentous growth)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|go:"GO:0071944"(cell periphery)|interpro:IPR018624|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|sgd:S000000375|dip:DIP-1694N|mint:P33754 - - crc64:E2A8BB4994A227D4 figure legend:"Fig. 6B (lower panel), 7A"|comment:Complex mass 287 kDa, standard deviation = 42 kDa|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/04 2014/10/16 rogid:Gi0aAi/lO9gi5h6LMgke4advNsM559292 rogid:KvIn7euv+AwTIngwnUh/lmdLyaw559292 intact-crc:AFDA719E2532AAFF|rigid:kl5v5RIqDGmk3pgYMBGmh+Dohag false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32915 uniprotkb:P39742 intact:EBI-16400|ensemblfungi:YLR378C|uniprotkb:D6VZ14 intact:EBI-16651|ensemblfungi:YLR292C|uniprotkb:D6VYT8 psi-mi:sc61a_yeast(display_long)|uniprotkb:Sec61 complex subunit SEC61(gene name synonym)|uniprotkb:L3502.5(orf name)|uniprotkb:YLR378C(locus name)|uniprotkb:SEC61(gene name)|psi-mi:SEC61(display_short)|uniprotkb:Sec61 complex subunit alpha(gene name synonym) psi-mi:sec72_yeast(display_long)|uniprotkb:SEC67(gene name synonym)|uniprotkb:SIM2(gene name synonym)|uniprotkb:L8003.18(orf name)|uniprotkb:YLR292C(locus name)|uniprotkb:SEC72(gene name)|psi-mi:SEC72(display_short)|uniprotkb:Sec62/63 complex 23 kDa subunit(gene name synonym) psi-mi:"MI:0040"(electron microscopy) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9354392|imex:IM-22312-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0070843"(misfolded protein transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|go:"GO:0044743"(protein transmembrane import into intracellular organelle)|ensemblfungi:YLR378C(gene)|ensemblfungi:YLR378C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|refseq:NP_013482.1|sgd:S000004370|dip:DIP-2433N|mint:P32915 ensemblfungi:YLR292C(gene)|ensemblfungi:YLR292C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAJ|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|rcsb pdb:7KAO|rcsb pdb:7KAP|refseq:NP_013395.1|sgd:S000004283|dip:DIP-2491N|mint:P39742 - - - figure legend:"Fig. 6B (lower panel), 7A"|comment:Complex mass 287 kDa, standard deviation = 42 kDa|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/04 2014/10/16 rogid:Gi0aAi/lO9gi5h6LMgke4advNsM559292 rogid:R6m5FOSsQ87OrJRnqo2hkjAtqkg559292 intact-crc:AFDA719E2532AAFF|rigid:kl5v5RIqDGmk3pgYMBGmh+Dohag false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21825 uniprotkb:P35179 intact:EBI-16632|ensemblfungi:YPL094C|uniprotkb:D6W3S3 intact:EBI-16406|ensemblfungi:YDR086C|uniprotkb:D6VS73 psi-mi:sec62_yeast(display_long)|uniprotkb:SEC62(gene name)|psi-mi:SEC62(display_short)|uniprotkb:YPL094C(locus name)|uniprotkb:LPG14C(orf name)|uniprotkb:Sec62/63 complex 30 kDa subunit(gene name synonym) psi-mi:sc61g_yeast(display_long)|uniprotkb:Sec61 complex subunit SSS1(gene name synonym)|uniprotkb:Ssh1 complex subunit SSS1(gene name synonym)|uniprotkb:D4475(orf name)|uniprotkb:YDR086C(locus name)|uniprotkb:SSS1(gene name)|psi-mi:SSS1(display_short)|uniprotkb:Sec61 complex subunit gamma(gene name synonym)|uniprotkb:Ssh1 complex subunit gamma(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9354312|imex:IM-22312-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL094C(gene)|ensemblfungi:YPL094C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|interpro:IPR004728(Translocation protein Sec62)|interpro:IPR011553(Translocation protein Sec62, ascomycota)|rcsb pdb:6ZZZ|rcsb pdb:7AFT|refseq:NP_015231.2|sgd:S000006015|dip:DIP-3827N|mint:P21825 ensemblfungi:YDR086C(gene)|ensemblfungi:YDR086C_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0071261"(Ssh1 translocon complex)|interpro:IPR001901(Protein secE/sec61-gamma protein)|interpro:IPR008158(Protein translocase SEC61 complex gamma subunit)|interpro:IPR023391|rcsb pdb:2WW9|rcsb pdb:2WWA|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|reactome:R-SCE-9609523|refseq:NP_010371.1|sgd:S000002493|dip:DIP-2432N|mint:P35179 - - - figure legend:Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/04/04 2014/10/16 rogid:ntcNjurhtyRtHO3uJOOcJXb2Meg559292 rogid:QIi5kN/8mDxTSvxRiJVi2JsPdws559292 intact-crc:A3D1C49CDD9A09DC|rigid:kl5v5RIqDGmk3pgYMBGmh+Dohag false ha tag:c-c - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:P21825 uniprotkb:P33754 intact:EBI-16632|ensemblfungi:YPL094C|uniprotkb:D6W3S3 intact:EBI-16647|ensemblfungi:YBR171W|uniprotkb:D6VQG7 psi-mi:sec62_yeast(display_long)|uniprotkb:SEC62(gene name)|psi-mi:SEC62(display_short)|uniprotkb:YPL094C(locus name)|uniprotkb:LPG14C(orf name)|uniprotkb:Sec62/63 complex 30 kDa subunit(gene name synonym) psi-mi:sec66_yeast(display_long)|uniprotkb:SEC71(gene name synonym)|uniprotkb:YBR1232(orf name)|uniprotkb:YBR171W(locus name)|uniprotkb:SEC66(gene name)|psi-mi:SEC66(display_short)|uniprotkb:HSS1(gene name synonym)|uniprotkb:Sec62/63 complex 31.5 kDa subunit(gene name synonym)|uniprotkb:Protein HSS1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9354312|imex:IM-22312-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL094C(gene)|ensemblfungi:YPL094C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|interpro:IPR004728(Translocation protein Sec62)|interpro:IPR011553(Translocation protein Sec62, ascomycota)|rcsb pdb:6ZZZ|rcsb pdb:7AFT|refseq:NP_015231.2|sgd:S000006015|dip:DIP-3827N|mint:P21825 refseq:NP_009730.3|ensemblfungi:YBR171W(gene)|ensemblfungi:YBR171W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030447"(filamentous growth)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|go:"GO:0071944"(cell periphery)|interpro:IPR018624|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|sgd:S000000375|dip:DIP-1694N|mint:P33754 - - crc64:E2A8BB4994A227D4 figure legend:Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/04/04 2014/10/16 rogid:ntcNjurhtyRtHO3uJOOcJXb2Meg559292 rogid:KvIn7euv+AwTIngwnUh/lmdLyaw559292 intact-crc:A3D1C49CDD9A09DC|rigid:kl5v5RIqDGmk3pgYMBGmh+Dohag false ha tag:c-c - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:P21825 uniprotkb:P52870 intact:EBI-16632|ensemblfungi:YPL094C|uniprotkb:D6W3S3 intact:EBI-16410|ensemblfungi:YER087C-B|uniprotkb:D3DLZ4 psi-mi:sec62_yeast(display_long)|uniprotkb:SEC62(gene name)|psi-mi:SEC62(display_short)|uniprotkb:YPL094C(locus name)|uniprotkb:LPG14C(orf name)|uniprotkb:Sec62/63 complex 30 kDa subunit(gene name synonym) psi-mi:sc6b1_yeast(display_long)|uniprotkb:Sec61 complex subunit SBH1(gene name synonym)|uniprotkb:YER087BC(orf name)|uniprotkb:YER087C-B(locus name)|uniprotkb:SBH1(gene name)|psi-mi:SBH1(display_short)|uniprotkb:SEB1(gene name synonym)|uniprotkb:Sec61 complex subunit beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9354312|imex:IM-22312-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL094C(gene)|ensemblfungi:YPL094C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|interpro:IPR004728(Translocation protein Sec62)|interpro:IPR011553(Translocation protein Sec62, ascomycota)|rcsb pdb:6ZZZ|rcsb pdb:7AFT|refseq:NP_015231.2|sgd:S000006015|dip:DIP-3827N|mint:P21825 ensemblfungi:YER087C-B(gene)|ensemblfungi:YER087C-B_mRNA(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|interpro:IPR016482(Preprotein translocase Sec, Sec61-beta subunit, eukarya)|interpro:IPR030671|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|sgd:S000002128|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|refseq:NP_011011.3|dip:DIP-5681N|mint:P52870 - - - figure legend:Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/04/04 2014/10/16 rogid:ntcNjurhtyRtHO3uJOOcJXb2Meg559292 rogid:9cYnDPhmMpAOdB2GV5TxikzpjI0559292 intact-crc:A3D1C49CDD9A09DC|rigid:kl5v5RIqDGmk3pgYMBGmh+Dohag false ha tag:c-c - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:P21825 uniprotkb:P14906 intact:EBI-16632|ensemblfungi:YPL094C|uniprotkb:D6W3S3 intact:EBI-16636|uniprotkb:Q08690|ensemblfungi:YOR254C|uniprotkb:D6W2V5 psi-mi:sec62_yeast(display_long)|uniprotkb:SEC62(gene name)|psi-mi:SEC62(display_short)|uniprotkb:YPL094C(locus name)|uniprotkb:LPG14C(orf name)|uniprotkb:Sec62/63 complex 30 kDa subunit(gene name synonym) psi-mi:sec63_yeast(display_long)|uniprotkb:PTL1(gene name synonym)|uniprotkb:YOR254C(locus name)|uniprotkb:SEC63(gene name)|psi-mi:SEC63(display_short)|uniprotkb:NPL1(gene name synonym)|uniprotkb:Sec62/63 complex 73 kDa subunit(gene name synonym)|uniprotkb:Protein NPL1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9354312|imex:IM-22312-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL094C(gene)|ensemblfungi:YPL094C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|interpro:IPR004728(Translocation protein Sec62)|interpro:IPR011553(Translocation protein Sec62, ascomycota)|rcsb pdb:6ZZZ|rcsb pdb:7AFT|refseq:NP_015231.2|sgd:S000006015|dip:DIP-3827N|mint:P21825 ensemblfungi:YOR254C(gene)|ensemblfungi:YOR254C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|go:"GO:0046967"(cytosol to endoplasmic reticulum transport)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004179(Sec63)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR018253|interpro:IPR027137|interpro:IPR036869|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAI|rcsb pdb:7KAU|rcsb pdb:7KB5|refseq:NP_014897.1|sgd:S000005780|dip:DIP-2396N|mint:P14906 - - - figure legend:Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/04/04 2014/10/16 rogid:ntcNjurhtyRtHO3uJOOcJXb2Meg559292 rogid:FcVMvm368fBcw0EH918+lqynntc559292 intact-crc:A3D1C49CDD9A09DC|rigid:kl5v5RIqDGmk3pgYMBGmh+Dohag false ha tag:c-c maltose binding protein tag:c-c - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:P21825 uniprotkb:P39742 intact:EBI-16632|ensemblfungi:YPL094C|uniprotkb:D6W3S3 intact:EBI-16651|ensemblfungi:YLR292C|uniprotkb:D6VYT8 psi-mi:sec62_yeast(display_long)|uniprotkb:SEC62(gene name)|psi-mi:SEC62(display_short)|uniprotkb:YPL094C(locus name)|uniprotkb:LPG14C(orf name)|uniprotkb:Sec62/63 complex 30 kDa subunit(gene name synonym) psi-mi:sec72_yeast(display_long)|uniprotkb:SEC67(gene name synonym)|uniprotkb:SIM2(gene name synonym)|uniprotkb:L8003.18(orf name)|uniprotkb:YLR292C(locus name)|uniprotkb:SEC72(gene name)|psi-mi:SEC72(display_short)|uniprotkb:Sec62/63 complex 23 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9354312|imex:IM-22312-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL094C(gene)|ensemblfungi:YPL094C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|interpro:IPR004728(Translocation protein Sec62)|interpro:IPR011553(Translocation protein Sec62, ascomycota)|rcsb pdb:6ZZZ|rcsb pdb:7AFT|refseq:NP_015231.2|sgd:S000006015|dip:DIP-3827N|mint:P21825 ensemblfungi:YLR292C(gene)|ensemblfungi:YLR292C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAJ|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|rcsb pdb:7KAO|rcsb pdb:7KAP|refseq:NP_013395.1|sgd:S000004283|dip:DIP-2491N|mint:P39742 - - - figure legend:Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/04/04 2014/10/16 rogid:ntcNjurhtyRtHO3uJOOcJXb2Meg559292 rogid:R6m5FOSsQ87OrJRnqo2hkjAtqkg559292 intact-crc:A3D1C49CDD9A09DC|rigid:kl5v5RIqDGmk3pgYMBGmh+Dohag false ha tag:c-c - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:P21825 uniprotkb:P32915 intact:EBI-16632|ensemblfungi:YPL094C|uniprotkb:D6W3S3 intact:EBI-16400|ensemblfungi:YLR378C|uniprotkb:D6VZ14 psi-mi:sec62_yeast(display_long)|uniprotkb:SEC62(gene name)|psi-mi:SEC62(display_short)|uniprotkb:YPL094C(locus name)|uniprotkb:LPG14C(orf name)|uniprotkb:Sec62/63 complex 30 kDa subunit(gene name synonym) psi-mi:sc61a_yeast(display_long)|uniprotkb:Sec61 complex subunit SEC61(gene name synonym)|uniprotkb:L3502.5(orf name)|uniprotkb:YLR378C(locus name)|uniprotkb:SEC61(gene name)|psi-mi:SEC61(display_short)|uniprotkb:Sec61 complex subunit alpha(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9354312|imex:IM-22312-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL094C(gene)|ensemblfungi:YPL094C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|interpro:IPR004728(Translocation protein Sec62)|interpro:IPR011553(Translocation protein Sec62, ascomycota)|rcsb pdb:6ZZZ|rcsb pdb:7AFT|refseq:NP_015231.2|sgd:S000006015|dip:DIP-3827N|mint:P21825 go:"GO:0070843"(misfolded protein transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|go:"GO:0044743"(protein transmembrane import into intracellular organelle)|ensemblfungi:YLR378C(gene)|ensemblfungi:YLR378C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|refseq:NP_013482.1|sgd:S000004370|dip:DIP-2433N|mint:P32915 - - - figure legend:Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/04/04 2014/10/16 rogid:ntcNjurhtyRtHO3uJOOcJXb2Meg559292 rogid:Gi0aAi/lO9gi5h6LMgke4advNsM559292 intact-crc:A3D1C49CDD9A09DC|rigid:kl5v5RIqDGmk3pgYMBGmh+Dohag false ha tag:c-c - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:P21825 uniprotkb:P39742 intact:EBI-16632|ensemblfungi:YPL094C|uniprotkb:D6W3S3 intact:EBI-16651|ensemblfungi:YLR292C|uniprotkb:D6VYT8 psi-mi:sec62_yeast(display_long)|uniprotkb:SEC62(gene name)|psi-mi:SEC62(display_short)|uniprotkb:YPL094C(locus name)|uniprotkb:LPG14C(orf name)|uniprotkb:Sec62/63 complex 30 kDa subunit(gene name synonym) psi-mi:sec72_yeast(display_long)|uniprotkb:SEC67(gene name synonym)|uniprotkb:SIM2(gene name synonym)|uniprotkb:L8003.18(orf name)|uniprotkb:YLR292C(locus name)|uniprotkb:SEC72(gene name)|psi-mi:SEC72(display_short)|uniprotkb:Sec62/63 complex 23 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9352317|imex:IM-22312-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL094C(gene)|ensemblfungi:YPL094C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|interpro:IPR004728(Translocation protein Sec62)|interpro:IPR011553(Translocation protein Sec62, ascomycota)|rcsb pdb:6ZZZ|rcsb pdb:7AFT|refseq:NP_015231.2|sgd:S000006015|dip:DIP-3827N|mint:P21825 ensemblfungi:YLR292C(gene)|ensemblfungi:YLR292C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAJ|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|rcsb pdb:7KAO|rcsb pdb:7KAP|refseq:NP_013395.1|sgd:S000004283|dip:DIP-2491N|mint:P39742 - - - figure legend:Fig. 2, 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/04/04 2014/10/16 rogid:ntcNjurhtyRtHO3uJOOcJXb2Meg559292 rogid:R6m5FOSsQ87OrJRnqo2hkjAtqkg559292 intact-crc:87F70EEFF7308CDD|rigid:kl5v5RIqDGmk3pgYMBGmh+Dohag false ha tag:c-c - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:P21825 uniprotkb:P14906 intact:EBI-16632|ensemblfungi:YPL094C|uniprotkb:D6W3S3 intact:EBI-16636|uniprotkb:Q08690|ensemblfungi:YOR254C|uniprotkb:D6W2V5 psi-mi:sec62_yeast(display_long)|uniprotkb:SEC62(gene name)|psi-mi:SEC62(display_short)|uniprotkb:YPL094C(locus name)|uniprotkb:LPG14C(orf name)|uniprotkb:Sec62/63 complex 30 kDa subunit(gene name synonym) psi-mi:sec63_yeast(display_long)|uniprotkb:PTL1(gene name synonym)|uniprotkb:YOR254C(locus name)|uniprotkb:SEC63(gene name)|psi-mi:SEC63(display_short)|uniprotkb:NPL1(gene name synonym)|uniprotkb:Sec62/63 complex 73 kDa subunit(gene name synonym)|uniprotkb:Protein NPL1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9352317|imex:IM-22312-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL094C(gene)|ensemblfungi:YPL094C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|interpro:IPR004728(Translocation protein Sec62)|interpro:IPR011553(Translocation protein Sec62, ascomycota)|rcsb pdb:6ZZZ|rcsb pdb:7AFT|refseq:NP_015231.2|sgd:S000006015|dip:DIP-3827N|mint:P21825 ensemblfungi:YOR254C(gene)|ensemblfungi:YOR254C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|go:"GO:0046967"(cytosol to endoplasmic reticulum transport)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004179(Sec63)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR018253|interpro:IPR027137|interpro:IPR036869|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAI|rcsb pdb:7KAU|rcsb pdb:7KB5|refseq:NP_014897.1|sgd:S000005780|dip:DIP-2396N|mint:P14906 - - - figure legend:Fig. 2, 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/04/04 2014/10/16 rogid:ntcNjurhtyRtHO3uJOOcJXb2Meg559292 rogid:FcVMvm368fBcw0EH918+lqynntc559292 intact-crc:87F70EEFF7308CDD|rigid:kl5v5RIqDGmk3pgYMBGmh+Dohag false ha tag:c-c - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:P21825 uniprotkb:P32915 intact:EBI-16632|ensemblfungi:YPL094C|uniprotkb:D6W3S3 intact:EBI-16400|ensemblfungi:YLR378C|uniprotkb:D6VZ14 psi-mi:sec62_yeast(display_long)|uniprotkb:SEC62(gene name)|psi-mi:SEC62(display_short)|uniprotkb:YPL094C(locus name)|uniprotkb:LPG14C(orf name)|uniprotkb:Sec62/63 complex 30 kDa subunit(gene name synonym) psi-mi:sc61a_yeast(display_long)|uniprotkb:Sec61 complex subunit SEC61(gene name synonym)|uniprotkb:L3502.5(orf name)|uniprotkb:YLR378C(locus name)|uniprotkb:SEC61(gene name)|psi-mi:SEC61(display_short)|uniprotkb:Sec61 complex subunit alpha(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9352317|imex:IM-22312-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL094C(gene)|ensemblfungi:YPL094C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|interpro:IPR004728(Translocation protein Sec62)|interpro:IPR011553(Translocation protein Sec62, ascomycota)|rcsb pdb:6ZZZ|rcsb pdb:7AFT|refseq:NP_015231.2|sgd:S000006015|dip:DIP-3827N|mint:P21825 go:"GO:0070843"(misfolded protein transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|go:"GO:0044743"(protein transmembrane import into intracellular organelle)|ensemblfungi:YLR378C(gene)|ensemblfungi:YLR378C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|refseq:NP_013482.1|sgd:S000004370|dip:DIP-2433N|mint:P32915 - - - figure legend:Fig. 2, 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/04/04 2014/10/16 rogid:ntcNjurhtyRtHO3uJOOcJXb2Meg559292 rogid:Gi0aAi/lO9gi5h6LMgke4advNsM559292 intact-crc:87F70EEFF7308CDD|rigid:kl5v5RIqDGmk3pgYMBGmh+Dohag false ha tag:c-c - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:P21825 uniprotkb:P35179 intact:EBI-16632|ensemblfungi:YPL094C|uniprotkb:D6W3S3 intact:EBI-16406|ensemblfungi:YDR086C|uniprotkb:D6VS73 psi-mi:sec62_yeast(display_long)|uniprotkb:SEC62(gene name)|psi-mi:SEC62(display_short)|uniprotkb:YPL094C(locus name)|uniprotkb:LPG14C(orf name)|uniprotkb:Sec62/63 complex 30 kDa subunit(gene name synonym) psi-mi:sc61g_yeast(display_long)|uniprotkb:Sec61 complex subunit SSS1(gene name synonym)|uniprotkb:Ssh1 complex subunit SSS1(gene name synonym)|uniprotkb:D4475(orf name)|uniprotkb:YDR086C(locus name)|uniprotkb:SSS1(gene name)|psi-mi:SSS1(display_short)|uniprotkb:Sec61 complex subunit gamma(gene name synonym)|uniprotkb:Ssh1 complex subunit gamma(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9352317|imex:IM-22312-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL094C(gene)|ensemblfungi:YPL094C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|interpro:IPR004728(Translocation protein Sec62)|interpro:IPR011553(Translocation protein Sec62, ascomycota)|rcsb pdb:6ZZZ|rcsb pdb:7AFT|refseq:NP_015231.2|sgd:S000006015|dip:DIP-3827N|mint:P21825 ensemblfungi:YDR086C(gene)|ensemblfungi:YDR086C_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0071261"(Ssh1 translocon complex)|interpro:IPR001901(Protein secE/sec61-gamma protein)|interpro:IPR008158(Protein translocase SEC61 complex gamma subunit)|interpro:IPR023391|rcsb pdb:2WW9|rcsb pdb:2WWA|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|reactome:R-SCE-9609523|refseq:NP_010371.1|sgd:S000002493|dip:DIP-2432N|mint:P35179 - - - figure legend:Fig. 2, 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/04/04 2014/10/16 rogid:ntcNjurhtyRtHO3uJOOcJXb2Meg559292 rogid:QIi5kN/8mDxTSvxRiJVi2JsPdws559292 intact-crc:87F70EEFF7308CDD|rigid:kl5v5RIqDGmk3pgYMBGmh+Dohag false ha tag:c-c - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:P21825 uniprotkb:P33754 intact:EBI-16632|ensemblfungi:YPL094C|uniprotkb:D6W3S3 intact:EBI-16647|ensemblfungi:YBR171W|uniprotkb:D6VQG7 psi-mi:sec62_yeast(display_long)|uniprotkb:SEC62(gene name)|psi-mi:SEC62(display_short)|uniprotkb:YPL094C(locus name)|uniprotkb:LPG14C(orf name)|uniprotkb:Sec62/63 complex 30 kDa subunit(gene name synonym) psi-mi:sec66_yeast(display_long)|uniprotkb:SEC71(gene name synonym)|uniprotkb:YBR1232(orf name)|uniprotkb:YBR171W(locus name)|uniprotkb:SEC66(gene name)|psi-mi:SEC66(display_short)|uniprotkb:HSS1(gene name synonym)|uniprotkb:Sec62/63 complex 31.5 kDa subunit(gene name synonym)|uniprotkb:Protein HSS1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9352317|imex:IM-22312-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL094C(gene)|ensemblfungi:YPL094C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|interpro:IPR004728(Translocation protein Sec62)|interpro:IPR011553(Translocation protein Sec62, ascomycota)|rcsb pdb:6ZZZ|rcsb pdb:7AFT|refseq:NP_015231.2|sgd:S000006015|dip:DIP-3827N|mint:P21825 refseq:NP_009730.3|ensemblfungi:YBR171W(gene)|ensemblfungi:YBR171W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030447"(filamentous growth)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|go:"GO:0071944"(cell periphery)|interpro:IPR018624|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|sgd:S000000375|dip:DIP-1694N|mint:P33754 - - crc64:E2A8BB4994A227D4 figure legend:Fig. 2, 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/04/04 2014/10/16 rogid:ntcNjurhtyRtHO3uJOOcJXb2Meg559292 rogid:KvIn7euv+AwTIngwnUh/lmdLyaw559292 intact-crc:87F70EEFF7308CDD|rigid:kl5v5RIqDGmk3pgYMBGmh+Dohag false ha tag:c-c - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:P21825 uniprotkb:P52870 intact:EBI-16632|ensemblfungi:YPL094C|uniprotkb:D6W3S3 intact:EBI-16410|ensemblfungi:YER087C-B|uniprotkb:D3DLZ4 psi-mi:sec62_yeast(display_long)|uniprotkb:SEC62(gene name)|psi-mi:SEC62(display_short)|uniprotkb:YPL094C(locus name)|uniprotkb:LPG14C(orf name)|uniprotkb:Sec62/63 complex 30 kDa subunit(gene name synonym) psi-mi:sc6b1_yeast(display_long)|uniprotkb:Sec61 complex subunit SBH1(gene name synonym)|uniprotkb:YER087BC(orf name)|uniprotkb:YER087C-B(locus name)|uniprotkb:SBH1(gene name)|psi-mi:SBH1(display_short)|uniprotkb:SEB1(gene name synonym)|uniprotkb:Sec61 complex subunit beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9352317|imex:IM-22312-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL094C(gene)|ensemblfungi:YPL094C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|interpro:IPR004728(Translocation protein Sec62)|interpro:IPR011553(Translocation protein Sec62, ascomycota)|rcsb pdb:6ZZZ|rcsb pdb:7AFT|refseq:NP_015231.2|sgd:S000006015|dip:DIP-3827N|mint:P21825 ensemblfungi:YER087C-B(gene)|ensemblfungi:YER087C-B_mRNA(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|interpro:IPR016482(Preprotein translocase Sec, Sec61-beta subunit, eukarya)|interpro:IPR030671|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|sgd:S000002128|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|refseq:NP_011011.3|dip:DIP-5681N|mint:P52870 - - - figure legend:Fig. 2, 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/04/04 2014/10/16 rogid:ntcNjurhtyRtHO3uJOOcJXb2Meg559292 rogid:9cYnDPhmMpAOdB2GV5TxikzpjI0559292 intact-crc:87F70EEFF7308CDD|rigid:kl5v5RIqDGmk3pgYMBGmh+Dohag false ha tag:c-c - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:P32915 uniprotkb:P35179 intact:EBI-16400|ensemblfungi:YLR378C|uniprotkb:D6VZ14 intact:EBI-16406|ensemblfungi:YDR086C|uniprotkb:D6VS73 psi-mi:sc61a_yeast(display_long)|uniprotkb:Sec61 complex subunit SEC61(gene name synonym)|uniprotkb:L3502.5(orf name)|uniprotkb:YLR378C(locus name)|uniprotkb:SEC61(gene name)|psi-mi:SEC61(display_short)|uniprotkb:Sec61 complex subunit alpha(gene name synonym) psi-mi:sc61g_yeast(display_long)|uniprotkb:Sec61 complex subunit SSS1(gene name synonym)|uniprotkb:Ssh1 complex subunit SSS1(gene name synonym)|uniprotkb:D4475(orf name)|uniprotkb:YDR086C(locus name)|uniprotkb:SSS1(gene name)|psi-mi:SSS1(display_short)|uniprotkb:Sec61 complex subunit gamma(gene name synonym)|uniprotkb:Ssh1 complex subunit gamma(gene name synonym) psi-mi:"MI:1024"(scanning electron microscopy) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9352347|imex:IM-22312-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0070843"(misfolded protein transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|go:"GO:0044743"(protein transmembrane import into intracellular organelle)|ensemblfungi:YLR378C(gene)|ensemblfungi:YLR378C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|refseq:NP_013482.1|sgd:S000004370|dip:DIP-2433N|mint:P32915 ensemblfungi:YDR086C(gene)|ensemblfungi:YDR086C_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0071261"(Ssh1 translocon complex)|interpro:IPR001901(Protein secE/sec61-gamma protein)|interpro:IPR008158(Protein translocase SEC61 complex gamma subunit)|interpro:IPR023391|rcsb pdb:2WW9|rcsb pdb:2WWA|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|reactome:R-SCE-9609523|refseq:NP_010371.1|sgd:S000002493|dip:DIP-2432N|mint:P35179 - - - figure legend:Fig. 3|comment:Complex mass 287 kDa, standard deviation = 42 kDa|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/04 2014/10/16 rogid:Gi0aAi/lO9gi5h6LMgke4advNsM559292 rogid:QIi5kN/8mDxTSvxRiJVi2JsPdws559292 intact-crc:BC6074353D84FD65|rigid:kl5v5RIqDGmk3pgYMBGmh+Dohag false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32915 uniprotkb:P52870 intact:EBI-16400|ensemblfungi:YLR378C|uniprotkb:D6VZ14 intact:EBI-16410|ensemblfungi:YER087C-B|uniprotkb:D3DLZ4 psi-mi:sc61a_yeast(display_long)|uniprotkb:Sec61 complex subunit SEC61(gene name synonym)|uniprotkb:L3502.5(orf name)|uniprotkb:YLR378C(locus name)|uniprotkb:SEC61(gene name)|psi-mi:SEC61(display_short)|uniprotkb:Sec61 complex subunit alpha(gene name synonym) psi-mi:sc6b1_yeast(display_long)|uniprotkb:Sec61 complex subunit SBH1(gene name synonym)|uniprotkb:YER087BC(orf name)|uniprotkb:YER087C-B(locus name)|uniprotkb:SBH1(gene name)|psi-mi:SBH1(display_short)|uniprotkb:SEB1(gene name synonym)|uniprotkb:Sec61 complex subunit beta(gene name synonym) psi-mi:"MI:1024"(scanning electron microscopy) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9352347|imex:IM-22312-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0070843"(misfolded protein transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|go:"GO:0044743"(protein transmembrane import into intracellular organelle)|ensemblfungi:YLR378C(gene)|ensemblfungi:YLR378C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|refseq:NP_013482.1|sgd:S000004370|dip:DIP-2433N|mint:P32915 ensemblfungi:YER087C-B(gene)|ensemblfungi:YER087C-B_mRNA(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|interpro:IPR016482(Preprotein translocase Sec, Sec61-beta subunit, eukarya)|interpro:IPR030671|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|sgd:S000002128|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|refseq:NP_011011.3|dip:DIP-5681N|mint:P52870 - - - figure legend:Fig. 3|comment:Complex mass 287 kDa, standard deviation = 42 kDa|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/04 2014/10/16 rogid:Gi0aAi/lO9gi5h6LMgke4advNsM559292 rogid:9cYnDPhmMpAOdB2GV5TxikzpjI0559292 intact-crc:BC6074353D84FD65|rigid:kl5v5RIqDGmk3pgYMBGmh+Dohag false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32915 uniprotkb:P21825 intact:EBI-16400|ensemblfungi:YLR378C|uniprotkb:D6VZ14 intact:EBI-16632|ensemblfungi:YPL094C|uniprotkb:D6W3S3 psi-mi:sc61a_yeast(display_long)|uniprotkb:Sec61 complex subunit SEC61(gene name synonym)|uniprotkb:L3502.5(orf name)|uniprotkb:YLR378C(locus name)|uniprotkb:SEC61(gene name)|psi-mi:SEC61(display_short)|uniprotkb:Sec61 complex subunit alpha(gene name synonym) psi-mi:sec62_yeast(display_long)|uniprotkb:SEC62(gene name)|psi-mi:SEC62(display_short)|uniprotkb:YPL094C(locus name)|uniprotkb:LPG14C(orf name)|uniprotkb:Sec62/63 complex 30 kDa subunit(gene name synonym) psi-mi:"MI:1024"(scanning electron microscopy) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9352347|imex:IM-22312-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0070843"(misfolded protein transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|go:"GO:0044743"(protein transmembrane import into intracellular organelle)|ensemblfungi:YLR378C(gene)|ensemblfungi:YLR378C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|refseq:NP_013482.1|sgd:S000004370|dip:DIP-2433N|mint:P32915 ensemblfungi:YPL094C(gene)|ensemblfungi:YPL094C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|interpro:IPR004728(Translocation protein Sec62)|interpro:IPR011553(Translocation protein Sec62, ascomycota)|rcsb pdb:6ZZZ|rcsb pdb:7AFT|refseq:NP_015231.2|sgd:S000006015|dip:DIP-3827N|mint:P21825 - - - figure legend:Fig. 3|comment:Complex mass 287 kDa, standard deviation = 42 kDa|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/04 2014/10/16 rogid:Gi0aAi/lO9gi5h6LMgke4advNsM559292 rogid:ntcNjurhtyRtHO3uJOOcJXb2Meg559292 intact-crc:BC6074353D84FD65|rigid:kl5v5RIqDGmk3pgYMBGmh+Dohag false - ha tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32915 uniprotkb:P14906 intact:EBI-16400|ensemblfungi:YLR378C|uniprotkb:D6VZ14 intact:EBI-16636|uniprotkb:Q08690|ensemblfungi:YOR254C|uniprotkb:D6W2V5 psi-mi:sc61a_yeast(display_long)|uniprotkb:Sec61 complex subunit SEC61(gene name synonym)|uniprotkb:L3502.5(orf name)|uniprotkb:YLR378C(locus name)|uniprotkb:SEC61(gene name)|psi-mi:SEC61(display_short)|uniprotkb:Sec61 complex subunit alpha(gene name synonym) psi-mi:sec63_yeast(display_long)|uniprotkb:PTL1(gene name synonym)|uniprotkb:YOR254C(locus name)|uniprotkb:SEC63(gene name)|psi-mi:SEC63(display_short)|uniprotkb:NPL1(gene name synonym)|uniprotkb:Sec62/63 complex 73 kDa subunit(gene name synonym)|uniprotkb:Protein NPL1(gene name synonym) psi-mi:"MI:1024"(scanning electron microscopy) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9352347|imex:IM-22312-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0070843"(misfolded protein transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|go:"GO:0044743"(protein transmembrane import into intracellular organelle)|ensemblfungi:YLR378C(gene)|ensemblfungi:YLR378C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|refseq:NP_013482.1|sgd:S000004370|dip:DIP-2433N|mint:P32915 ensemblfungi:YOR254C(gene)|ensemblfungi:YOR254C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|go:"GO:0046967"(cytosol to endoplasmic reticulum transport)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004179(Sec63)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR018253|interpro:IPR027137|interpro:IPR036869|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAI|rcsb pdb:7KAU|rcsb pdb:7KB5|refseq:NP_014897.1|sgd:S000005780|dip:DIP-2396N|mint:P14906 - - - figure legend:Fig. 3|comment:Complex mass 287 kDa, standard deviation = 42 kDa|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/04 2014/10/16 rogid:Gi0aAi/lO9gi5h6LMgke4advNsM559292 rogid:FcVMvm368fBcw0EH918+lqynntc559292 intact-crc:BC6074353D84FD65|rigid:kl5v5RIqDGmk3pgYMBGmh+Dohag false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32915 uniprotkb:P33754 intact:EBI-16400|ensemblfungi:YLR378C|uniprotkb:D6VZ14 intact:EBI-16647|ensemblfungi:YBR171W|uniprotkb:D6VQG7 psi-mi:sc61a_yeast(display_long)|uniprotkb:Sec61 complex subunit SEC61(gene name synonym)|uniprotkb:L3502.5(orf name)|uniprotkb:YLR378C(locus name)|uniprotkb:SEC61(gene name)|psi-mi:SEC61(display_short)|uniprotkb:Sec61 complex subunit alpha(gene name synonym) psi-mi:sec66_yeast(display_long)|uniprotkb:SEC71(gene name synonym)|uniprotkb:YBR1232(orf name)|uniprotkb:YBR171W(locus name)|uniprotkb:SEC66(gene name)|psi-mi:SEC66(display_short)|uniprotkb:HSS1(gene name synonym)|uniprotkb:Sec62/63 complex 31.5 kDa subunit(gene name synonym)|uniprotkb:Protein HSS1(gene name synonym) psi-mi:"MI:1024"(scanning electron microscopy) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9352347|imex:IM-22312-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0070843"(misfolded protein transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|go:"GO:0044743"(protein transmembrane import into intracellular organelle)|ensemblfungi:YLR378C(gene)|ensemblfungi:YLR378C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|refseq:NP_013482.1|sgd:S000004370|dip:DIP-2433N|mint:P32915 refseq:NP_009730.3|ensemblfungi:YBR171W(gene)|ensemblfungi:YBR171W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030447"(filamentous growth)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|go:"GO:0071944"(cell periphery)|interpro:IPR018624|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|sgd:S000000375|dip:DIP-1694N|mint:P33754 - - crc64:E2A8BB4994A227D4 figure legend:Fig. 3|comment:Complex mass 287 kDa, standard deviation = 42 kDa|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/04 2014/10/16 rogid:Gi0aAi/lO9gi5h6LMgke4advNsM559292 rogid:KvIn7euv+AwTIngwnUh/lmdLyaw559292 intact-crc:BC6074353D84FD65|rigid:kl5v5RIqDGmk3pgYMBGmh+Dohag false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32915 uniprotkb:P39742 intact:EBI-16400|ensemblfungi:YLR378C|uniprotkb:D6VZ14 intact:EBI-16651|ensemblfungi:YLR292C|uniprotkb:D6VYT8 psi-mi:sc61a_yeast(display_long)|uniprotkb:Sec61 complex subunit SEC61(gene name synonym)|uniprotkb:L3502.5(orf name)|uniprotkb:YLR378C(locus name)|uniprotkb:SEC61(gene name)|psi-mi:SEC61(display_short)|uniprotkb:Sec61 complex subunit alpha(gene name synonym) psi-mi:sec72_yeast(display_long)|uniprotkb:SEC67(gene name synonym)|uniprotkb:SIM2(gene name synonym)|uniprotkb:L8003.18(orf name)|uniprotkb:YLR292C(locus name)|uniprotkb:SEC72(gene name)|psi-mi:SEC72(display_short)|uniprotkb:Sec62/63 complex 23 kDa subunit(gene name synonym) psi-mi:"MI:1024"(scanning electron microscopy) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9352347|imex:IM-22312-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0070843"(misfolded protein transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|go:"GO:0044743"(protein transmembrane import into intracellular organelle)|ensemblfungi:YLR378C(gene)|ensemblfungi:YLR378C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|refseq:NP_013482.1|sgd:S000004370|dip:DIP-2433N|mint:P32915 ensemblfungi:YLR292C(gene)|ensemblfungi:YLR292C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAJ|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|rcsb pdb:7KAO|rcsb pdb:7KAP|refseq:NP_013395.1|sgd:S000004283|dip:DIP-2491N|mint:P39742 - - - figure legend:Fig. 3|comment:Complex mass 287 kDa, standard deviation = 42 kDa|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/04 2014/10/16 rogid:Gi0aAi/lO9gi5h6LMgke4advNsM559292 rogid:R6m5FOSsQ87OrJRnqo2hkjAtqkg559292 intact-crc:BC6074353D84FD65|rigid:kl5v5RIqDGmk3pgYMBGmh+Dohag false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39742 uniprotkb:P21825 intact:EBI-16651|ensemblfungi:YLR292C|uniprotkb:D6VYT8 intact:EBI-16632|ensemblfungi:YPL094C|uniprotkb:D6W3S3 psi-mi:sec72_yeast(display_long)|uniprotkb:SEC67(gene name synonym)|uniprotkb:SIM2(gene name synonym)|uniprotkb:L8003.18(orf name)|uniprotkb:YLR292C(locus name)|uniprotkb:SEC72(gene name)|psi-mi:SEC72(display_short)|uniprotkb:Sec62/63 complex 23 kDa subunit(gene name synonym) psi-mi:sec62_yeast(display_long)|uniprotkb:SEC62(gene name)|psi-mi:SEC62(display_short)|uniprotkb:YPL094C(locus name)|uniprotkb:LPG14C(orf name)|uniprotkb:Sec62/63 complex 30 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9352251|imex:IM-22312-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLR292C(gene)|ensemblfungi:YLR292C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAJ|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|rcsb pdb:7KAO|rcsb pdb:7KAP|refseq:NP_013395.1|sgd:S000004283|dip:DIP-2491N|mint:P39742 ensemblfungi:YPL094C(gene)|ensemblfungi:YPL094C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|interpro:IPR004728(Translocation protein Sec62)|interpro:IPR011553(Translocation protein Sec62, ascomycota)|rcsb pdb:6ZZZ|rcsb pdb:7AFT|refseq:NP_015231.2|sgd:S000006015|dip:DIP-3827N|mint:P21825 - - - figure legend:Fig. 1C, 1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/04/04 2014/10/16 rogid:R6m5FOSsQ87OrJRnqo2hkjAtqkg559292 rogid:ntcNjurhtyRtHO3uJOOcJXb2Meg559292 intact-crc:BD475A149BFA1886|rigid:PDgi5RZR4hTAXrtZb0kg334E1W8 false flag tag:c-c ha tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P33754 uniprotkb:P21825 intact:EBI-16647|ensemblfungi:YBR171W|uniprotkb:D6VQG7 intact:EBI-16632|ensemblfungi:YPL094C|uniprotkb:D6W3S3 psi-mi:sec66_yeast(display_long)|uniprotkb:SEC71(gene name synonym)|uniprotkb:YBR1232(orf name)|uniprotkb:YBR171W(locus name)|uniprotkb:SEC66(gene name)|psi-mi:SEC66(display_short)|uniprotkb:HSS1(gene name synonym)|uniprotkb:Sec62/63 complex 31.5 kDa subunit(gene name synonym)|uniprotkb:Protein HSS1(gene name synonym) psi-mi:sec62_yeast(display_long)|uniprotkb:SEC62(gene name)|psi-mi:SEC62(display_short)|uniprotkb:YPL094C(locus name)|uniprotkb:LPG14C(orf name)|uniprotkb:Sec62/63 complex 30 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9352243|imex:IM-22312-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009730.3|ensemblfungi:YBR171W(gene)|ensemblfungi:YBR171W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030447"(filamentous growth)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|go:"GO:0071944"(cell periphery)|interpro:IPR018624|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|sgd:S000000375|dip:DIP-1694N|mint:P33754 ensemblfungi:YPL094C(gene)|ensemblfungi:YPL094C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|interpro:IPR004728(Translocation protein Sec62)|interpro:IPR011553(Translocation protein Sec62, ascomycota)|rcsb pdb:6ZZZ|rcsb pdb:7AFT|refseq:NP_015231.2|sgd:S000006015|dip:DIP-3827N|mint:P21825 - crc64:E2A8BB4994A227D4 - figure legend:Fig. 1C, 1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/04/04 2014/10/16 rogid:KvIn7euv+AwTIngwnUh/lmdLyaw559292 rogid:ntcNjurhtyRtHO3uJOOcJXb2Meg559292 intact-crc:B3A67E41587C2757|rigid:TLbAbwMrTIDfwT7mZRmRhCThNvw false flag tag:c-c ha tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P21825 uniprotkb:P35179 intact:EBI-16632|ensemblfungi:YPL094C|uniprotkb:D6W3S3 intact:EBI-16406|ensemblfungi:YDR086C|uniprotkb:D6VS73 psi-mi:sec62_yeast(display_long)|uniprotkb:SEC62(gene name)|psi-mi:SEC62(display_short)|uniprotkb:YPL094C(locus name)|uniprotkb:LPG14C(orf name)|uniprotkb:Sec62/63 complex 30 kDa subunit(gene name synonym) psi-mi:sc61g_yeast(display_long)|uniprotkb:Sec61 complex subunit SSS1(gene name synonym)|uniprotkb:Ssh1 complex subunit SSS1(gene name synonym)|uniprotkb:D4475(orf name)|uniprotkb:YDR086C(locus name)|uniprotkb:SSS1(gene name)|psi-mi:SSS1(display_short)|uniprotkb:Sec61 complex subunit gamma(gene name synonym)|uniprotkb:Ssh1 complex subunit gamma(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9352275|imex:IM-22312-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL094C(gene)|ensemblfungi:YPL094C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|interpro:IPR004728(Translocation protein Sec62)|interpro:IPR011553(Translocation protein Sec62, ascomycota)|rcsb pdb:6ZZZ|rcsb pdb:7AFT|refseq:NP_015231.2|sgd:S000006015|dip:DIP-3827N|mint:P21825 ensemblfungi:YDR086C(gene)|ensemblfungi:YDR086C_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0071261"(Ssh1 translocon complex)|interpro:IPR001901(Protein secE/sec61-gamma protein)|interpro:IPR008158(Protein translocase SEC61 complex gamma subunit)|interpro:IPR023391|rcsb pdb:2WW9|rcsb pdb:2WWA|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|reactome:R-SCE-9609523|refseq:NP_010371.1|sgd:S000002493|dip:DIP-2432N|mint:P35179 - - - figure legend:Fig. 1C, 1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/04/04 2014/10/16 rogid:ntcNjurhtyRtHO3uJOOcJXb2Meg559292 rogid:QIi5kN/8mDxTSvxRiJVi2JsPdws559292 intact-crc:5739BDDA06C24955|rigid:tmV5fpGJRGbDTVu1wTwzN4lWo9E false ha tag:c-c flag tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P52870 uniprotkb:P21825 intact:EBI-16410|ensemblfungi:YER087C-B|uniprotkb:D3DLZ4 intact:EBI-16632|ensemblfungi:YPL094C|uniprotkb:D6W3S3 psi-mi:sc6b1_yeast(display_long)|uniprotkb:Sec61 complex subunit SBH1(gene name synonym)|uniprotkb:YER087BC(orf name)|uniprotkb:YER087C-B(locus name)|uniprotkb:SBH1(gene name)|psi-mi:SBH1(display_short)|uniprotkb:SEB1(gene name synonym)|uniprotkb:Sec61 complex subunit beta(gene name synonym) psi-mi:sec62_yeast(display_long)|uniprotkb:SEC62(gene name)|psi-mi:SEC62(display_short)|uniprotkb:YPL094C(locus name)|uniprotkb:LPG14C(orf name)|uniprotkb:Sec62/63 complex 30 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9352267|imex:IM-22312-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YER087C-B(gene)|ensemblfungi:YER087C-B_mRNA(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|interpro:IPR016482(Preprotein translocase Sec, Sec61-beta subunit, eukarya)|interpro:IPR030671|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|sgd:S000002128|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|refseq:NP_011011.3|dip:DIP-5681N|mint:P52870 ensemblfungi:YPL094C(gene)|ensemblfungi:YPL094C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|interpro:IPR004728(Translocation protein Sec62)|interpro:IPR011553(Translocation protein Sec62, ascomycota)|rcsb pdb:6ZZZ|rcsb pdb:7AFT|refseq:NP_015231.2|sgd:S000006015|dip:DIP-3827N|mint:P21825 - - - figure legend:Fig. 1C, 1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/04/04 2014/10/16 rogid:9cYnDPhmMpAOdB2GV5TxikzpjI0559292 rogid:ntcNjurhtyRtHO3uJOOcJXb2Meg559292 intact-crc:78F2EED86A1DE750|rigid:XZJZKS4v+AgOUXm1YuzfayLNquQ false flag tag:c-c ha tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P32915 uniprotkb:P21825 intact:EBI-16400|ensemblfungi:YLR378C|uniprotkb:D6VZ14 intact:EBI-16632|ensemblfungi:YPL094C|uniprotkb:D6W3S3 psi-mi:sc61a_yeast(display_long)|uniprotkb:Sec61 complex subunit SEC61(gene name synonym)|uniprotkb:L3502.5(orf name)|uniprotkb:YLR378C(locus name)|uniprotkb:SEC61(gene name)|psi-mi:SEC61(display_short)|uniprotkb:Sec61 complex subunit alpha(gene name synonym) psi-mi:sec62_yeast(display_long)|uniprotkb:SEC62(gene name)|psi-mi:SEC62(display_short)|uniprotkb:YPL094C(locus name)|uniprotkb:LPG14C(orf name)|uniprotkb:Sec62/63 complex 30 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9352259|imex:IM-22312-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0070843"(misfolded protein transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|go:"GO:0044743"(protein transmembrane import into intracellular organelle)|ensemblfungi:YLR378C(gene)|ensemblfungi:YLR378C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|refseq:NP_013482.1|sgd:S000004370|dip:DIP-2433N|mint:P32915 ensemblfungi:YPL094C(gene)|ensemblfungi:YPL094C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|interpro:IPR004728(Translocation protein Sec62)|interpro:IPR011553(Translocation protein Sec62, ascomycota)|rcsb pdb:6ZZZ|rcsb pdb:7AFT|refseq:NP_015231.2|sgd:S000006015|dip:DIP-3827N|mint:P21825 - - - figure legend:Fig. 1C, 1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/04/04 2014/10/16 rogid:Gi0aAi/lO9gi5h6LMgke4advNsM559292 rogid:ntcNjurhtyRtHO3uJOOcJXb2Meg559292 intact-crc:8DF180462F1E0AF0|rigid:9+6ckcR5B9lkz52FMc6dwoe1oPk false flag tag:c-c ha tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P14906 uniprotkb:P21825 intact:EBI-16636|uniprotkb:Q08690|ensemblfungi:YOR254C|uniprotkb:D6W2V5 intact:EBI-16632|ensemblfungi:YPL094C|uniprotkb:D6W3S3 psi-mi:sec63_yeast(display_long)|uniprotkb:PTL1(gene name synonym)|uniprotkb:YOR254C(locus name)|uniprotkb:SEC63(gene name)|psi-mi:SEC63(display_short)|uniprotkb:NPL1(gene name synonym)|uniprotkb:Sec62/63 complex 73 kDa subunit(gene name synonym)|uniprotkb:Protein NPL1(gene name synonym) psi-mi:sec62_yeast(display_long)|uniprotkb:SEC62(gene name)|psi-mi:SEC62(display_short)|uniprotkb:YPL094C(locus name)|uniprotkb:LPG14C(orf name)|uniprotkb:Sec62/63 complex 30 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Harada et al. (2011) pubmed:20826819|imex:IM-22312 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9351424|imex:IM-22312-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YOR254C(gene)|ensemblfungi:YOR254C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|go:"GO:0046967"(cytosol to endoplasmic reticulum transport)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004179(Sec63)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR018253|interpro:IPR027137|interpro:IPR036869|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAI|rcsb pdb:7KAU|rcsb pdb:7KB5|refseq:NP_014897.1|sgd:S000005780|dip:DIP-2396N|mint:P14906 ensemblfungi:YPL094C(gene)|ensemblfungi:YPL094C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|interpro:IPR004728(Translocation protein Sec62)|interpro:IPR011553(Translocation protein Sec62, ascomycota)|rcsb pdb:6ZZZ|rcsb pdb:7AFT|refseq:NP_015231.2|sgd:S000006015|dip:DIP-3827N|mint:P21825 - - - figure legend:Fig. 1C, 1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/04/04 2014/10/16 rogid:FcVMvm368fBcw0EH918+lqynntc559292 rogid:ntcNjurhtyRtHO3uJOOcJXb2Meg559292 intact-crc:CA23E9036C2AFA50|rigid:ogYXP54KSSOF9MglfN+8+Qq5x+w false flag tag:c-c ha tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)