#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B chebi:"CHEBI:29105" uniprotkb:P08228 intact:EBI-968340 intact:EBI-1635090|ensembl:ENSMUSP00000023707 psi-mi:"zinc(2+)"(display_short)|psi-mi:"CHEBI:29105"(display_long) psi-mi:sodc_mouse(display_long)|uniprotkb:Sod1(gene name)|psi-mi:Sod1(display_short) psi-mi:"MI:0114"(x-ray crystallography) Seetharaman et al. (2010) pubmed:20727846|imex:IM-22192 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-9209490|wwpdb:3gtt|imex:IM-22192-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_035564.1|dip:DIP-48691N|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043209"(myelin sheath)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046688"(response to copper ion)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048678"(response to axon injury)|go:"GO:0050665"(hydrogen peroxide biosynthetic process)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051087"(chaperone binding)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060047"(heart contraction)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0060087"(relaxation of vascular associated smooth muscle)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097332"(response to antipsychotic drug)|go:"GO:1902177"(positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001424(Superoxide dismutase, copper/zinc binding)|interpro:IPR018152|interpro:IPR024134|interpro:IPR036423|mint:P08228|rcsb pdb:3GTT|rcsb pdb:3GTV|rcsb pdb:3LTV|reactome:R-MMU-114608|reactome:R-MMU-3299685|ensembl:ENSMUSG00000022982(gene)|ensembl:ENSMUST00000023707(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0000303"(response to superoxide)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001975"(response to amphetamine)|go:"GO:0002262"(myeloid cell homeostasis)|go:"GO:0004784"(superoxide dismutase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005764"(lysosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007566"(embryo implantation)|go:"GO:0007568"(aging)|go:"GO:0007569"(cell aging)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009408"(response to heat)|go:"GO:0010033"(response to organic substance)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0019899"(enzyme binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030346"(protein phosphatase 2B binding)|go:"GO:0031045"(dense core granule)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034465"(response to carbon monoxide)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042554"(superoxide anion generation)|go:"GO:0042802"(identical protein binding) - - - figure legend:Table 1|3d-r-factors:Rworking = 0.16 Rfree = 0.2|3d-resolution:2.4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/02/18 2019/01/30 - rogid:BeyfJ/d3Dn+3pu1Nkl8n/x4Qriw10090 intact-crc:9AAFBEB8C85B94A6 false - - 6 2 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)