#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P09758	uniprotkb:O14493	intact:EBI-4324738|uniprotkb:Q15658|uniprotkb:Q6FG48|uniprotkb:Q7Z7Q4|uniprotkb:Q96QD2|ensembl:ENSP00000360269	intact:EBI-9316372|ensembl:ENSP00000342445|ensembl:ENSP00000388639|ensembl:ENSP00000409544	psi-mi:tacd2_human(display_long)|uniprotkb:TACSTD2(gene name)|psi-mi:TACSTD2(display_short)|uniprotkb:GA733-1(gene name synonym)|uniprotkb:M1S1(gene name synonym)|uniprotkb:TROP2(gene name synonym)|uniprotkb:Cell surface glycoprotein Trop-2(gene name synonym)|uniprotkb:Membrane component chromosome 1 surface marker 1(gene name synonym)|uniprotkb:Pancreatic carcinoma marker protein GA733-1(gene name synonym)	psi-mi:cld4_human(display_long)|uniprotkb:CLDN4(gene name)|psi-mi:CLDN4(display_short)|uniprotkb:CPER(gene name synonym)|uniprotkb:CPETR1(gene name synonym)|uniprotkb:WBSCR8(gene name synonym)|uniprotkb:Clostridium perfringens enterotoxin receptor(gene name synonym)|uniprotkb:Williams-Beuren syndrome chromosomal region 8 protein(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Nakatsukasa et al. (2010)	pubmed:20651236|imex:IM-22294	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9302237|imex:IM-22294-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002344.2|ensembl:ENSG00000184292(gene)|ensembl:ENST00000371225(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007601"(visual perception)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010633"(negative regulation of epithelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0050896"(response to stimulus)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1900028"(negative regulation of ruffle assembly)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000738"(positive regulation of stem cell differentiation)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR036857|interpro:IPR043406|rcsb pdb:2MAE|rcsb pdb:2MVK|rcsb pdb:2MVL|go:"GO:0090191"(negative regulation of branching involved in ureteric bud morphogenesis)	refseq:NP_001296.1|ensembl:ENSG00000189143(gene)|ensembl:ENST00000340958(transcript)|ensembl:ENST00000431918(transcript)|ensembl:ENST00000435050(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006821"(chloride transport)|go:"GO:0007155"(cell adhesion)|go:"GO:0007565"(female pregnancy)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016338"(calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032570"(response to progesterone)|go:"GO:0034707"(chloride channel complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070160"(tight junction)|go:"GO:0070293"(renal absorption)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:1905050"(positive regulation of metallopeptidase activity)|interpro:IPR003550(Claudin-4)|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|interpro:IPR006187(Claudin)|interpro:IPR017974|rcsb pdb:5B2G|rcsb pdb:7KP4|reactome:R-HSA-420029	go:"GO:0005886"(plasma membrane)	-	-	figure legend:2B/Cii|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-cornea)|taxid:9606(Human cornea)	-	2014/03/25	2014/10/16	rogid:kBM5ZjCHTtc3dIwXR7jdWywzwbw9606	rogid:X6JP76fG2Xq3uAh8j4fQ8XbGRmU9606	intact-crc:9C13BD112D745701|rigid:pQS9MXedvhEvY/F4hS9z4+LSExY	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:Q07157	uniprotkb:P09758	intact:EBI-79553|uniprotkb:B4E3K1|ensembl:ENSP00000281537|ensembl:ENSP00000484535|uniprotkb:Q2NKP3|uniprotkb:Q4ZGJ6	intact:EBI-4324738|uniprotkb:Q15658|uniprotkb:Q6FG48|uniprotkb:Q7Z7Q4|uniprotkb:Q96QD2|ensembl:ENSP00000360269	psi-mi:zo1_human(display_long)|uniprotkb:TJP1(gene name)|psi-mi:TJP1(display_short)|uniprotkb:ZO1(gene name synonym)|uniprotkb:Zonula occludens protein 1(gene name synonym)|uniprotkb:Zona occludens protein 1(gene name synonym)|uniprotkb:Tight junction protein 1(gene name synonym)	psi-mi:tacd2_human(display_long)|uniprotkb:TACSTD2(gene name)|psi-mi:TACSTD2(display_short)|uniprotkb:GA733-1(gene name synonym)|uniprotkb:M1S1(gene name synonym)|uniprotkb:TROP2(gene name synonym)|uniprotkb:Cell surface glycoprotein Trop-2(gene name synonym)|uniprotkb:Membrane component chromosome 1 surface marker 1(gene name synonym)|uniprotkb:Pancreatic carcinoma marker protein GA733-1(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Nakatsukasa et al. (2010)	pubmed:20651236|imex:IM-22294	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9302246|imex:IM-22294-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000104067(gene)|ensembl:ENSG00000277401(gene)|ensembl:ENST00000346128(transcript)|go:"GO:0002102"(podosome)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005921"(gap junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042995"(cell projection)|go:"GO:0043066"(negative regulation of apoptotic process)|ensembl:ENST00000621049(transcript)|go:"GO:0043296"(apical junction complex)|go:"GO:0045177"(apical part of cell)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0070160"(tight junction)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0150105"(protein localization to cell-cell junction)|go:"GO:1901888"(regulation of cell junction assembly)|go:"GO:1902396"(protein localization to bicellular tight junction)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1905605"(positive regulation of blood-brain barrier permeability)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000250"(negative regulation of actin cytoskeleton reorganization)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR000906(ZU5)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR005417(Zona occludens protein)|interpro:IPR005418(Zona occludens protein ZO-1)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR036028|interpro:IPR035597|interpro:IPR036034|mint:Q07157|rcsb pdb:2H2B|rcsb pdb:2H2C|rcsb pdb:2H3M|rcsb pdb:2JWE|rcsb pdb:2KXR|rcsb pdb:2KXS|rcsb pdb:2RCZ|rcsb pdb:3CYY|rcsb pdb:3LH5|rcsb pdb:3SHU|rcsb pdb:3SHW|rcsb pdb:3TSV|rcsb pdb:3TSW|rcsb pdb:3TSZ|rcsb pdb:4OEO|rcsb pdb:4OEP|rcsb pdb:4Q2Q|rcsb pdb:4YYX|reactome:R-HSA-191650|reactome:R-HSA-2028269|reactome:R-HSA-351906|reactome:R-HSA-8935964|refseq:NP_003248.3|refseq:NP_783297.2	refseq:NP_002344.2|ensembl:ENSG00000184292(gene)|ensembl:ENST00000371225(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007601"(visual perception)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010633"(negative regulation of epithelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0050896"(response to stimulus)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1900028"(negative regulation of ruffle assembly)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000738"(positive regulation of stem cell differentiation)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR036857|interpro:IPR043406|rcsb pdb:2MAE|rcsb pdb:2MVK|rcsb pdb:2MVL|go:"GO:0090191"(negative regulation of branching involved in ureteric bud morphogenesis)	go:"GO:0005886"(plasma membrane)	-	-	figure legend:2B|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-cornea)|taxid:9606(Human cornea)	-	2014/03/25	2014/10/16	rogid:/Yi7U3TcH6kPu4A/bQ5Nj0QeU2w9606	rogid:kBM5ZjCHTtc3dIwXR7jdWywzwbw9606	intact-crc:E1061E3206BAF306|rigid:LwwPde55YytFdar8oatD7rnLEFI	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P09758	uniprotkb:O95832	intact:EBI-4324738|uniprotkb:Q15658|uniprotkb:Q6FG48|uniprotkb:Q7Z7Q4|uniprotkb:Q96QD2|ensembl:ENSP00000360269	intact:EBI-723889|ensembl:ENSP00000295522	psi-mi:tacd2_human(display_long)|uniprotkb:TACSTD2(gene name)|psi-mi:TACSTD2(display_short)|uniprotkb:GA733-1(gene name synonym)|uniprotkb:M1S1(gene name synonym)|uniprotkb:TROP2(gene name synonym)|uniprotkb:Cell surface glycoprotein Trop-2(gene name synonym)|uniprotkb:Membrane component chromosome 1 surface marker 1(gene name synonym)|uniprotkb:Pancreatic carcinoma marker protein GA733-1(gene name synonym)	psi-mi:cld1_human(display_long)|uniprotkb:Senescence-associated epithelial membrane protein(gene name synonym)|uniprotkb:CLDN1(gene name)|psi-mi:CLDN1(display_short)|uniprotkb:CLD1(gene name synonym)|uniprotkb:SEMP1(gene name synonym)|uniprotkb:UNQ481/PRO944(orf name)	psi-mi:"MI:0813"(proximity ligation assay)	Nakatsukasa et al. (2010)	pubmed:20651236|imex:IM-22294	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9302215|imex:IM-22294-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002344.2|ensembl:ENSG00000184292(gene)|ensembl:ENST00000371225(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007601"(visual perception)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010633"(negative regulation of epithelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0050896"(response to stimulus)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1900028"(negative regulation of ruffle assembly)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000738"(positive regulation of stem cell differentiation)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR036857|interpro:IPR043406|rcsb pdb:2MAE|rcsb pdb:2MVK|rcsb pdb:2MVL|go:"GO:0090191"(negative regulation of branching involved in ureteric bud morphogenesis)	refseq:NP_066924.1|ensembl:ENSG00000163347(gene)|ensembl:ENST00000295522(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0007568"(aging)|go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016338"(calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034331"(cell junction maintenance)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042538"(hyperosmotic salinity response)|go:"GO:0042802"(identical protein binding)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045471"(response to ethanol)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0060054"(positive regulation of epithelial cell proliferation involved in wound healing)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0061772"(xenobiotic transport across blood-nerve barrier)|go:"GO:0070160"(tight junction)|go:"GO:0070673"(response to interleukin-18)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0071284"(cellular response to lead ion)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0097421"(liver regeneration)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1903545"(cellular response to butyrate)|interpro:IPR003548(Claudin-1)|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|interpro:IPR006187(Claudin)|interpro:IPR017974|reactome:R-HSA-420029	go:"GO:0005886"(plasma membrane)	-	-	figure legend:2B/C|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-cornea)|taxid:9606(Human cornea)	-	2014/03/25	2014/10/16	rogid:kBM5ZjCHTtc3dIwXR7jdWywzwbw9606	rogid:38MxEaRUYqwdpkJgOUMtw0/gJsY9606	intact-crc:57A509C562FD2F96|rigid:kswhrOxx84RtWT6tEoO7yw7NMnk	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P09758	uniprotkb:O95471	intact:EBI-4324738|uniprotkb:Q15658|uniprotkb:Q6FG48|uniprotkb:Q7Z7Q4|uniprotkb:Q96QD2|ensembl:ENSP00000360269	intact:EBI-740744|uniprotkb:Q6IPN3|uniprotkb:Q7Z4Y7|uniprotkb:Q9BVN0|uniprotkb:B2R9X7|uniprotkb:D3DTP0|ensembl:ENSP00000353475|ensembl:ENSP00000396638|ensembl:ENSP00000500298|ensembl:ENSP00000500460	psi-mi:tacd2_human(display_long)|uniprotkb:TACSTD2(gene name)|psi-mi:TACSTD2(display_short)|uniprotkb:GA733-1(gene name synonym)|uniprotkb:M1S1(gene name synonym)|uniprotkb:TROP2(gene name synonym)|uniprotkb:Cell surface glycoprotein Trop-2(gene name synonym)|uniprotkb:Membrane component chromosome 1 surface marker 1(gene name synonym)|uniprotkb:Pancreatic carcinoma marker protein GA733-1(gene name synonym)	psi-mi:cld7_human(display_long)|uniprotkb:CLDN7(gene name)|psi-mi:CLDN7(display_short)|uniprotkb:CEPTRL2(gene name synonym)|uniprotkb:CPETRL2(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Nakatsukasa et al. (2010)	pubmed:20651236|imex:IM-22294	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9302231|imex:IM-22294-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002344.2|ensembl:ENSG00000184292(gene)|ensembl:ENST00000371225(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007601"(visual perception)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010633"(negative regulation of epithelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0050896"(response to stimulus)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1900028"(negative regulation of ruffle assembly)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000738"(positive regulation of stem cell differentiation)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR036857|interpro:IPR043406|rcsb pdb:2MAE|rcsb pdb:2MVK|rcsb pdb:2MVL|go:"GO:0090191"(negative regulation of branching involved in ureteric bud morphogenesis)	refseq:NP_001171951.1|refseq:NP_001171952.1|refseq:NP_001298.3|ensembl:ENST00000360325(transcript)|ensembl:ENST00000397317(transcript)|ensembl:ENST00000672374(transcript)|ensembl:ENST00000672443(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016338"(calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules)|go:"GO:0042802"(identical protein binding)|go:"GO:0070830"(bicellular tight junction assembly)|interpro:IPR003552(Claudin-7)|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|interpro:IPR006187(Claudin)|interpro:IPR017974|reactome:R-HSA-420029|ensembl:ENSG00000181885(gene)|ensembl:ENSG00000288292(gene)	go:"GO:0005886"(plasma membrane)	-	-	figure legend:2B/Ci|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-cornea)|taxid:9606(Human cornea)	-	2014/03/25	2014/10/16	rogid:kBM5ZjCHTtc3dIwXR7jdWywzwbw9606	rogid:fuMpDFEAVbThvzDfD0At7mjiQCE9606	intact-crc:19C22C810D3AD446|rigid:a6hUyX4cQtukC+55VPlmQMB+1HQ	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P09758	uniprotkb:O95471	intact:EBI-4324738|uniprotkb:Q15658|uniprotkb:Q6FG48|uniprotkb:Q7Z7Q4|uniprotkb:Q96QD2|ensembl:ENSP00000360269	intact:EBI-740744|uniprotkb:Q6IPN3|uniprotkb:Q7Z4Y7|uniprotkb:Q9BVN0|uniprotkb:B2R9X7|uniprotkb:D3DTP0|ensembl:ENSP00000353475|ensembl:ENSP00000396638|ensembl:ENSP00000500298|ensembl:ENSP00000500460	psi-mi:tacd2_human(display_long)|uniprotkb:TACSTD2(gene name)|psi-mi:TACSTD2(display_short)|uniprotkb:GA733-1(gene name synonym)|uniprotkb:M1S1(gene name synonym)|uniprotkb:TROP2(gene name synonym)|uniprotkb:Cell surface glycoprotein Trop-2(gene name synonym)|uniprotkb:Membrane component chromosome 1 surface marker 1(gene name synonym)|uniprotkb:Pancreatic carcinoma marker protein GA733-1(gene name synonym)	psi-mi:cld7_human(display_long)|uniprotkb:CLDN7(gene name)|psi-mi:CLDN7(display_short)|uniprotkb:CEPTRL2(gene name synonym)|uniprotkb:CPETRL2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Nakatsukasa et al. (2010)	pubmed:20651236|imex:IM-22294	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9302190|imex:IM-22294-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002344.2|ensembl:ENSG00000184292(gene)|ensembl:ENST00000371225(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007601"(visual perception)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010633"(negative regulation of epithelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0050896"(response to stimulus)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1900028"(negative regulation of ruffle assembly)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000738"(positive regulation of stem cell differentiation)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR036857|interpro:IPR043406|rcsb pdb:2MAE|rcsb pdb:2MVK|rcsb pdb:2MVL|go:"GO:0090191"(negative regulation of branching involved in ureteric bud morphogenesis)	refseq:NP_001171951.1|refseq:NP_001171952.1|refseq:NP_001298.3|ensembl:ENST00000360325(transcript)|ensembl:ENST00000397317(transcript)|ensembl:ENST00000672374(transcript)|ensembl:ENST00000672443(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016338"(calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules)|go:"GO:0042802"(identical protein binding)|go:"GO:0070830"(bicellular tight junction assembly)|interpro:IPR003552(Claudin-7)|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|interpro:IPR006187(Claudin)|interpro:IPR017974|reactome:R-HSA-420029|ensembl:ENSG00000181885(gene)|ensembl:ENSG00000288292(gene)	-	-	-	figure legend:2A|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hce-t-15)|taxid:9606(Human HCE-T-15 Immortalised Corneal Epithelium cell line)	-	2014/03/25	2014/10/16	rogid:kBM5ZjCHTtc3dIwXR7jdWywzwbw9606	rogid:fuMpDFEAVbThvzDfD0At7mjiQCE9606	intact-crc:5FAA9D1994DF667C|rigid:qfUYHvavCyI2dTlxYcOI9ufJZFw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P09758	uniprotkb:O95832	intact:EBI-4324738|uniprotkb:Q15658|uniprotkb:Q6FG48|uniprotkb:Q7Z7Q4|uniprotkb:Q96QD2|ensembl:ENSP00000360269	intact:EBI-723889|ensembl:ENSP00000295522	psi-mi:tacd2_human(display_long)|uniprotkb:TACSTD2(gene name)|psi-mi:TACSTD2(display_short)|uniprotkb:GA733-1(gene name synonym)|uniprotkb:M1S1(gene name synonym)|uniprotkb:TROP2(gene name synonym)|uniprotkb:Cell surface glycoprotein Trop-2(gene name synonym)|uniprotkb:Membrane component chromosome 1 surface marker 1(gene name synonym)|uniprotkb:Pancreatic carcinoma marker protein GA733-1(gene name synonym)	psi-mi:cld1_human(display_long)|uniprotkb:Senescence-associated epithelial membrane protein(gene name synonym)|uniprotkb:CLDN1(gene name)|psi-mi:CLDN1(display_short)|uniprotkb:CLD1(gene name synonym)|uniprotkb:SEMP1(gene name synonym)|uniprotkb:UNQ481/PRO944(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Nakatsukasa et al. (2010)	pubmed:20651236|imex:IM-22294	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9302190|imex:IM-22294-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002344.2|ensembl:ENSG00000184292(gene)|ensembl:ENST00000371225(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007601"(visual perception)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010633"(negative regulation of epithelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0050896"(response to stimulus)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1900028"(negative regulation of ruffle assembly)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000738"(positive regulation of stem cell differentiation)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR036857|interpro:IPR043406|rcsb pdb:2MAE|rcsb pdb:2MVK|rcsb pdb:2MVL|go:"GO:0090191"(negative regulation of branching involved in ureteric bud morphogenesis)	refseq:NP_066924.1|ensembl:ENSG00000163347(gene)|ensembl:ENST00000295522(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0007568"(aging)|go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016338"(calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034331"(cell junction maintenance)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042538"(hyperosmotic salinity response)|go:"GO:0042802"(identical protein binding)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045471"(response to ethanol)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0060054"(positive regulation of epithelial cell proliferation involved in wound healing)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0061772"(xenobiotic transport across blood-nerve barrier)|go:"GO:0070160"(tight junction)|go:"GO:0070673"(response to interleukin-18)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0071284"(cellular response to lead ion)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0097421"(liver regeneration)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1903545"(cellular response to butyrate)|interpro:IPR003548(Claudin-1)|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|interpro:IPR006187(Claudin)|interpro:IPR017974|reactome:R-HSA-420029	-	-	-	figure legend:2A|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hce-t-15)|taxid:9606(Human HCE-T-15 Immortalised Corneal Epithelium cell line)	-	2014/03/25	2014/10/16	rogid:kBM5ZjCHTtc3dIwXR7jdWywzwbw9606	rogid:38MxEaRUYqwdpkJgOUMtw0/gJsY9606	intact-crc:5FAA9D1994DF667C|rigid:qfUYHvavCyI2dTlxYcOI9ufJZFw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)