#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8IV16 uniprotkb:P06858 intact:EBI-9080234|uniprotkb:Q6P3T2|uniprotkb:Q86W15|intact:EBI-28970171|ensembl:ENSP00000480053 intact:EBI-715909|uniprotkb:Q16282|uniprotkb:Q16283|uniprotkb:Q96FC4|uniprotkb:B2R5T9|ensembl:ENSP00000497642 psi-mi:hdbp1_human(display_long)|uniprotkb:GPIHBP1(gene name)|psi-mi:GPIHBP1(display_short)|uniprotkb:HBP1(gene name synonym)|uniprotkb:High density lipoprotein-binding protein 1(gene name synonym) psi-mi:lipl_human(display_long)|uniprotkb:LPL(gene name)|psi-mi:LPL(display_short)|uniprotkb:LIPD(gene name synonym)|uniprotkb:Phospholipase A1(gene name synonym) psi-mi:"MI:0400"(affinity technology) Franssen et al. (2010) pubmed:20124439|imex:IM-22126 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-9082185|imex:IM-22126-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000480053|refseq:NP_001288701.1|refseq:NP_835466.2|ensembl:ENSG00000277494(gene)|ensembl:ENST00000622500(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008289"(lipid binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017038"(protein import)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035473"(lipase binding)|go:"GO:0035478"(chylomicron binding)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0045056"(transcytosis)|go:"GO:0050821"(protein stabilization)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0071503"(response to heparin)|go:"GO:0071813"(lipoprotein particle binding)|go:"GO:0090321"(positive regulation of chylomicron remnant clearance)|go:"GO:0140318"(protein transporter activity)|rcsb pdb:6E7K|rcsb pdb:6OAU|rcsb pdb:6OAZ|rcsb pdb:6OB0|reactome:R-HSA-163125|reactome:R-HSA-8963889|reactome:R-HSA-8963901|reactome:R-HSA-975634|interpro:IPR016054(Ly-6 antigen / uPA receptor -like) refseq:NP_000228.1|ensembl:ENSG00000175445(gene)|ensembl:ENST00000650287(transcript)|go:"GO:0004465"(lipoprotein lipase activity)|go:"GO:0004620"(phospholipase activity)|go:"GO:0004806"(triglyceride lipase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0008201"(heparin binding)|go:"GO:0008970"(phospholipase A1 activity)|go:"GO:0009409"(response to cold)|go:"GO:0009749"(response to glucose)|go:"GO:0010744"(positive regulation of macrophage derived foam cell differentiation)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010886"(positive regulation of cholesterol storage)|go:"GO:0010890"(positive regulation of sequestering of triglyceride)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016298"(lipase activity)|go:"GO:0017129"(triglyceride binding)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0031670"(cellular response to nutrient)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034371"(chylomicron remodeling)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0042493"|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0052739"(phosphatidylserine 1-acylhydrolase activity)|go:"GO:0052740"(1-acyl-2-lysophosphatidylserine acylhydrolase activity)|go:"GO:0055096"(low-density lipoprotein particle mediated signaling)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071813"(lipoprotein particle binding)|go:"GO:1900077"(negative regulation of cellular response to insulin stimulus)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR000734(Lipase)|interpro:IPR001024(Lipoxygenase, LH2)|interpro:IPR002330(Lipoprotein lipase)|interpro:IPR013818(Lipase, N-terminal)|interpro:IPR016272(Lipoprotein lipase, LIPH)|interpro:IPR029058|interpro:IPR033906|interpro:IPR036392|mint:P06858|rcsb pdb:6E7K|rcsb pdb:6OAU|rcsb pdb:6OAZ|rcsb pdb:6OB0|rcsb pdb:6WN4|reactome:R-HSA-381340|reactome:R-HSA-8963889|reactome:R-HSA-8963901|reactome:R-HSA-975634 - - - figure legend:Fig.5|antagonist:"Heparin (CHEBI:28304)"|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/01/10 2014/10/16 rogid:xEkQbSvjU2SMRcjD/a0DbC5MwKg9606 rogid:PM82k8/f6nyAUhaTSvIUvjVkbYU9606 intact-crc:F744A720235F5EED|rigid:ahkslBJFhIyTQRdeFaGAQoQFP98 false mutation decreasing interaction:65-65|mutation decreasing interaction:115-115|s tag:?-? v5 tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)