#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P70227	uniprotkb:Q60664	intact:EBI-6910019|ensembl:ENSMUSP00000038150|uniprotkb:Q5DWM4|uniprotkb:Q8CED5|uniprotkb:Q91Z08	intact:EBI-688116|uniprotkb:Q7TMU8	psi-mi:itpr3_mouse(display_long)|uniprotkb:Itpr3(gene name)|psi-mi:Itpr3(display_short)|uniprotkb:IP3 receptor isoform 3(gene name synonym)|uniprotkb:Type 3 inositol 1,4,5-trisphosphate receptor(gene name synonym)	psi-mi:irag2_mouse(display_long)|uniprotkb:Irag2(gene name)|psi-mi:Irag2(display_short)|uniprotkb:Jaw1(gene name synonym)|uniprotkb:Lrmp(gene name synonym)|uniprotkb:Lymphoid-restricted membrane protein(gene name synonym)|uniprotkb:Protein Jaw1(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Shindo et al. (2010)	pubmed:20071408	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9212709	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050913"(sensory perception of bitter taste)|go:"GO:0050916"(sensory perception of sweet taste)|go:"GO:0050917"(sensory perception of umami taste)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070679"(inositol 1,4,5 trisphosphate binding)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0098793"(presynapse)|interpro:IPR000493(Inositol 1,4,5-trisphosphate-binding protein receptor)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR005821(Ion transport)|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|interpro:IPR016093(MIR motif)|interpro:IPR035910|interpro:IPR036300|rcsb pdb:3JRR|reactome:R-MMU-114508|reactome:R-MMU-139853|reactome:R-MMU-381676|reactome:R-MMU-5578775|reactome:R-MMU-983695|ensembl:ENSMUSG00000042644(gene)|ensembl:ENSMUST00000049308(transcript)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005220"(inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007613"(memory)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0043235"(receptor complex)|go:"GO:0043533"(inositol 1,3,4,5 tetrakisphosphate binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045177"(apical part of cell)|refseq:NP_542120.2	interpro:IPR008677(MRVI1)|refseq:NP_001268909.1|go:"GO:0000922"(spindle pole)|go:"GO:0002376"(immune system process)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005694"(chromosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006997"(nucleus organization)|go:"GO:0007338"(single fertilization)|go:"GO:0008017"(microtubule binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)	-	-	-	figure legend:3|comment:This interaction is also detected in fungiform papillae.|curation depth:mimix curation	taxid:10090(mouse-vallate papilla)|taxid:10090(Mus musculus)	-	2014/02/20	2014/10/16	rogid:/rO5sZ0rWGGYvxB/Erfrr4wF/xY10090	rogid:DyUxo5y3yVY7O83jUohbdC42XsA10090	intact-crc:7689EF808C4A0B39|rigid:LNjh+yOV6UvYOjYxfADRwRE8iXU	false	-	-	-	-	psi-mi:"MI:1199"(anti-tag immunohistochemistry)	psi-mi:"MI:1199"(anti-tag immunohistochemistry)
uniprotkb:Q60664	uniprotkb:Q63269	intact:EBI-688116|uniprotkb:Q7TMU8	intact:EBI-9212786	psi-mi:irag2_mouse(display_long)|uniprotkb:Irag2(gene name)|psi-mi:Irag2(display_short)|uniprotkb:Jaw1(gene name synonym)|uniprotkb:Lrmp(gene name synonym)|uniprotkb:Lymphoid-restricted membrane protein(gene name synonym)|uniprotkb:Protein Jaw1(gene name synonym)	psi-mi:itpr3_rat(display_long)|uniprotkb:Itpr3(gene name)|psi-mi:Itpr3(display_short)|uniprotkb:IP3 receptor isoform 3(gene name synonym)|uniprotkb:Type 3 inositol 1,4,5-trisphosphate receptor(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Shindo et al. (2010)	pubmed:20071408	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9212784	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR008677(MRVI1)|refseq:NP_001268909.1|go:"GO:0000922"(spindle pole)|go:"GO:0002376"(immune system process)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005694"(chromosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006997"(nucleus organization)|go:"GO:0007338"(single fertilization)|go:"GO:0008017"(microtubule binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)	rgd:2934|refseq:NP_037270.1|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|interpro:IPR000493(Inositol 1,4,5-trisphosphate-binding protein receptor)|interpro:IPR005821(Ion transport)|interpro:IPR016093(MIR motif)|interpro:IPR013662(RyR and IP3R Homology associated)|mint:Q63269|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005220"(inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007613"(memory)|go:"GO:0015085"(calcium ion transmembrane transporter activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0043235"(receptor complex)|go:"GO:0043533"(inositol 1,3,4,5 tetrakisphosphate binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050913"(sensory perception of bitter taste)|go:"GO:0050916"(sensory perception of sweet taste)|go:"GO:0050917"(sensory perception of umami taste)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070679"(inositol 1,4,5 trisphosphate binding)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0098793"(presynapse)|reactome:R-RNO-114508|reactome:R-RNO-139853|reactome:R-RNO-381676|reactome:R-RNO-5578775|reactome:R-RNO-983695|interpro:IPR035910|interpro:IPR036300	-	-	-	figure legend:4b|curation depth:mimix curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2014/02/20	2014/10/16	rogid:DyUxo5y3yVY7O83jUohbdC42XsA10090	rogid:oRMNVKgAZmFh2eZEcEBXUUvMK7o10116	intact-crc:39E465B6F0819B38|rigid:7P2OcuBxyWOsv6w8nmZHC2E24Ec	false	-	-	-	-	psi-mi:"MI:1201"(anti-tag immunocytochemistry)	psi-mi:"MI:1201"(anti-tag immunocytochemistry)
uniprotkb:Q60664	uniprotkb:Q63269	intact:EBI-688116|uniprotkb:Q7TMU8	intact:EBI-9212786	psi-mi:irag2_mouse(display_long)|uniprotkb:Irag2(gene name)|psi-mi:Irag2(display_short)|uniprotkb:Jaw1(gene name synonym)|uniprotkb:Lrmp(gene name synonym)|uniprotkb:Lymphoid-restricted membrane protein(gene name synonym)|uniprotkb:Protein Jaw1(gene name synonym)	psi-mi:itpr3_rat(display_long)|uniprotkb:Itpr3(gene name)|psi-mi:Itpr3(display_short)|uniprotkb:IP3 receptor isoform 3(gene name synonym)|uniprotkb:Type 3 inositol 1,4,5-trisphosphate receptor(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shindo et al. (2010)	pubmed:20071408	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9212906	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR008677(MRVI1)|refseq:NP_001268909.1|go:"GO:0000922"(spindle pole)|go:"GO:0002376"(immune system process)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005694"(chromosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006997"(nucleus organization)|go:"GO:0007338"(single fertilization)|go:"GO:0008017"(microtubule binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)	rgd:2934|refseq:NP_037270.1|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|interpro:IPR000493(Inositol 1,4,5-trisphosphate-binding protein receptor)|interpro:IPR005821(Ion transport)|interpro:IPR016093(MIR motif)|interpro:IPR013662(RyR and IP3R Homology associated)|mint:Q63269|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005220"(inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007613"(memory)|go:"GO:0015085"(calcium ion transmembrane transporter activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0043235"(receptor complex)|go:"GO:0043533"(inositol 1,3,4,5 tetrakisphosphate binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050913"(sensory perception of bitter taste)|go:"GO:0050916"(sensory perception of sweet taste)|go:"GO:0050917"(sensory perception of umami taste)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070679"(inositol 1,4,5 trisphosphate binding)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0098793"(presynapse)|reactome:R-RNO-114508|reactome:R-RNO-139853|reactome:R-RNO-381676|reactome:R-RNO-5578775|reactome:R-RNO-983695|interpro:IPR035910|interpro:IPR036300	-	-	-	figure legend:4c|curation depth:mimix curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2014/02/20	2014/10/16	rogid:DyUxo5y3yVY7O83jUohbdC42XsA10090	rogid:oRMNVKgAZmFh2eZEcEBXUUvMK7o10116	intact-crc:55E70A210368837D|rigid:7P2OcuBxyWOsv6w8nmZHC2E24Ec	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)