#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B ensembl:ENSG00000183813 uniprotkb:P15408 intact:EBI-10046020 intact:EBI-3893419|uniprotkb:B2RD58|uniprotkb:B3KP27|uniprotkb:B4DYV4|uniprotkb:Q6FG46|ensembl:ENSP00000264716 psi-mi:ccr4_human_gene(display_short)|psi-mi:ENSG00000183813(display_long) psi-mi:fosl2_human(display_long)|uniprotkb:FOSL2(gene name)|psi-mi:FOSL2(display_short)|uniprotkb:FRA2(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Nakayama et al. (2008) pubmed:18071306|imex:IM-23609 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10046038|imex:IM-23609-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:XP_016859226.1|refseq:NP_005244.1|dip:DIP-48788N|ensembl:ENSG00000075426(gene)|ensembl:ENST00000264716(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003334"(keratinocyte development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008219"(cell death)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029814 - - - figure legend:Fig. 4b|causality statement:P15408 increases expression at RNA level of ENSG00000183813|causality statement:P15408 and P17535 increases expression at RNA level of ENSG00000183813|causality statement:P15408 and P17275 increases expression at RNA level of ENSG00000183813|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-atl)|taxid:9606(Homo sapiens adult T-cell lymphoma cell) - 2014/12/18 2019/01/30 - rogid:+iPQyqskvPskPMg378TYKhOJ86s9606 intact-crc:DC8A3093827F5E9F false binding-associated region:?-? - - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) ensembl:ENSG00000183813 uniprotkb:P17275 intact:EBI-10046020 intact:EBI-748062|uniprotkb:Q96GH3|ensembl:ENSP00000303315 psi-mi:ccr4_human_gene(display_short)|psi-mi:ENSG00000183813(display_long) psi-mi:junb_human(display_long)|uniprotkb:JUNB(gene name)|psi-mi:JUNB(display_short) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Nakayama et al. (2008) pubmed:18071306|imex:IM-23609 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10046045|imex:IM-23609-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_002220.1|ensembl:ENSG00000171223(gene)|ensembl:ENST00000302754(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0033687"(osteoblast proliferation)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029822|mint:P17275|reactome:R-HSA-2173796|reactome:R-HSA-6785807|reactome:R-HSA-9031628|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|dip:DIP-1052N - - - figure legend:Fig. 4b|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-atl)|taxid:9606(Homo sapiens adult T-cell lymphoma cell) - 2014/12/18 2019/01/30 - rogid:p2UBpMzVG+A8AV7UCH4jYTsoPF89606 intact-crc:4E2BF050CEECB703 false binding-associated region:?-? - - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) uniprotkb:P17535 ensembl:ENSG00000183813 intact:EBI-2682803|uniprotkb:Q53EK9|ensembl:ENSP00000252818 intact:EBI-10046020 psi-mi:jund_human(display_long)|uniprotkb:JUND(gene name)|psi-mi:JUND(display_short) psi-mi:ccr4_human_gene(display_short)|psi-mi:ENSG00000183813(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Nakayama et al. (2008) pubmed:18071306|imex:IM-23609 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10046051|imex:IM-23609-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_001273897.1|refseq:NP_005345.3|ensembl:ENSG00000130522(gene)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043032"(positive regulation of macrophage activation)|ensembl:ENST00000252818(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|interpro:IPR029823|mint:P17535|rcsb pdb:3U86|rcsb pdb:5VPA|rcsb pdb:5VPB|rcsb pdb:5VPC|rcsb pdb:5VPD|rcsb pdb:5VPE|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|rcsb pdb:5VPF|reactome:R-HSA-9018519|reactome:R-HSA-9031628|go:"GO:0002076"(osteoblast development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007568"(aging)|dip:DIP-1053N - - - - figure legend:Fig. 4b|causality statement:P17535 increases expression at RNA level of ENSG00000183813|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-atl)|taxid:9606(Homo sapiens adult T-cell lymphoma cell) - 2014/12/18 2019/01/30 rogid:npmTGULvlKr4hC8HfmK19GUopf49606 - intact-crc:A2050D19BE084A1C false - binding-associated region:?-? - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) intact:EBI-10046032 uniprotkb:P15408 - intact:EBI-3893419|uniprotkb:B2RD58|uniprotkb:B3KP27|uniprotkb:B4DYV4|uniprotkb:Q6FG46|ensembl:ENSP00000264716 psi-mi:ccr4_human_ap1-site_dna-probe(display_short)|psi-mi:EBI-10046032(display_long) psi-mi:fosl2_human(display_long)|uniprotkb:FOSL2(gene name)|psi-mi:FOSL2(display_short)|uniprotkb:FRA2(gene name synonym) psi-mi:"MI:0892"(solid phase assay) Nakayama et al. (2008) pubmed:18071306|imex:IM-23609 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-10046236|imex:IM-23609-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0319"(deoxyribonucleic acid) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183813(see-also) refseq:XP_016859226.1|refseq:NP_005244.1|dip:DIP-48788N|ensembl:ENSG00000075426(gene)|ensembl:ENST00000264716(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003334"(keratinocyte development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008219"(cell death)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029814 - - - figure legend:Fig. 4a|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/12/18 2014/12/18 - rogid:+iPQyqskvPskPMg378TYKhOJ86s9606 intact-crc:13ACBEFA66A4397C false biotin tag:?-? - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:P15408 intact:EBI-10046032 intact:EBI-3893419|uniprotkb:B2RD58|uniprotkb:B3KP27|uniprotkb:B4DYV4|uniprotkb:Q6FG46|ensembl:ENSP00000264716 - psi-mi:fosl2_human(display_long)|uniprotkb:FOSL2(gene name)|psi-mi:FOSL2(display_short)|uniprotkb:FRA2(gene name synonym) psi-mi:ccr4_human_ap1-site_dna-probe(display_short)|psi-mi:EBI-10046032(display_long) psi-mi:"MI:0892"(solid phase assay) Nakayama et al. (2008) pubmed:18071306|imex:IM-23609 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-10046111|imex:IM-23609-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0319"(deoxyribonucleic acid) refseq:XP_016859226.1|refseq:NP_005244.1|dip:DIP-48788N|ensembl:ENSG00000075426(gene)|ensembl:ENST00000264716(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003334"(keratinocyte development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008219"(cell death)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029814 ensembl:ENSG00000183813(see-also) - - - figure legend:Fig. 4a|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/12/18 2019/01/30 rogid:+iPQyqskvPskPMg378TYKhOJ86s9606 - intact-crc:D416C062F7F805A1 false - biotin tag:?-? - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) intact:EBI-10046032 uniprotkb:P15408 - intact:EBI-3893419|uniprotkb:B2RD58|uniprotkb:B3KP27|uniprotkb:B4DYV4|uniprotkb:Q6FG46|ensembl:ENSP00000264716 psi-mi:ccr4_human_ap1-site_dna-probe(display_short)|psi-mi:EBI-10046032(display_long) psi-mi:fosl2_human(display_long)|uniprotkb:FOSL2(gene name)|psi-mi:FOSL2(display_short)|uniprotkb:FRA2(gene name synonym) psi-mi:"MI:0892"(solid phase assay) Nakayama et al. (2008) pubmed:18071306|imex:IM-23609 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10046155|imex:IM-23609-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0319"(deoxyribonucleic acid) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183813(see-also) refseq:XP_016859226.1|refseq:NP_005244.1|dip:DIP-48788N|ensembl:ENSG00000075426(gene)|ensembl:ENST00000264716(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003334"(keratinocyte development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008219"(cell death)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029814 - - - figure legend:Fig. 4a|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/12/18 2014/12/18 - rogid:+iPQyqskvPskPMg378TYKhOJ86s9606 intact-crc:A02F54F19E3E18AB false biotin tag:?-? - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) intact:EBI-10046032 intact:EBI-10046032 - - psi-mi:ccr4_human_ap1-site_dna-probe(display_short)|psi-mi:EBI-10046032(display_long) psi-mi:ccr4_human_ap1-site_dna-probe(display_short)|psi-mi:EBI-10046032(display_long) psi-mi:"MI:0892"(solid phase assay) Nakayama et al. (2008) pubmed:18071306|imex:IM-23609 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10046155|imex:IM-23609-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0319"(deoxyribonucleic acid) psi-mi:"MI:0319"(deoxyribonucleic acid) ensembl:ENSG00000183813(see-also) ensembl:ENSG00000183813(see-also) - - - figure legend:Fig. 4a|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/12/18 2014/12/18 - - intact-crc:A02F54F19E3E18AB false biotin tag:?-? mutation decreasing interaction:10-10,12-12 - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) intact:EBI-10046032 uniprotkb:P15408 - intact:EBI-3893419|uniprotkb:B2RD58|uniprotkb:B3KP27|uniprotkb:B4DYV4|uniprotkb:Q6FG46|ensembl:ENSP00000264716 psi-mi:ccr4_human_ap1-site_dna-probe(display_short)|psi-mi:EBI-10046032(display_long) psi-mi:fosl2_human(display_long)|uniprotkb:FOSL2(gene name)|psi-mi:FOSL2(display_short)|uniprotkb:FRA2(gene name synonym) psi-mi:"MI:0892"(solid phase assay) Nakayama et al. (2008) pubmed:18071306|imex:IM-23609 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10046268|imex:IM-23609-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0319"(deoxyribonucleic acid) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183813(see-also) refseq:XP_016859226.1|refseq:NP_005244.1|dip:DIP-48788N|ensembl:ENSG00000075426(gene)|ensembl:ENST00000264716(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003334"(keratinocyte development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008219"(cell death)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029814 - - - figure legend:Fig. 4a|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/12/18 2014/12/18 - rogid:+iPQyqskvPskPMg378TYKhOJ86s9606 intact-crc:626F512EC9A668D5 false biotin tag:?-? - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) intact:EBI-10046032 intact:EBI-10046032 - - psi-mi:ccr4_human_ap1-site_dna-probe(display_short)|psi-mi:EBI-10046032(display_long) psi-mi:ccr4_human_ap1-site_dna-probe(display_short)|psi-mi:EBI-10046032(display_long) psi-mi:"MI:0892"(solid phase assay) Nakayama et al. (2008) pubmed:18071306|imex:IM-23609 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10046268|imex:IM-23609-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0319"(deoxyribonucleic acid) psi-mi:"MI:0319"(deoxyribonucleic acid) ensembl:ENSG00000183813(see-also) ensembl:ENSG00000183813(see-also) - - - figure legend:Fig. 4a|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/12/18 2014/12/18 - - intact-crc:626F512EC9A668D5 false biotin tag:?-? mutation decreasing interaction:10-10,12-12 - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:P17275 intact:EBI-10046032 intact:EBI-748062|uniprotkb:Q96GH3|ensembl:ENSP00000303315 - psi-mi:junb_human(display_long)|uniprotkb:JUNB(gene name)|psi-mi:JUNB(display_short) psi-mi:ccr4_human_ap1-site_dna-probe(display_short)|psi-mi:EBI-10046032(display_long) psi-mi:"MI:0892"(solid phase assay) Nakayama et al. (2008) pubmed:18071306|imex:IM-23609 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-10046167|imex:IM-23609-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0319"(deoxyribonucleic acid) refseq:NP_002220.1|ensembl:ENSG00000171223(gene)|ensembl:ENST00000302754(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0033687"(osteoblast proliferation)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029822|mint:P17275|reactome:R-HSA-2173796|reactome:R-HSA-6785807|reactome:R-HSA-9031628|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|dip:DIP-1052N ensembl:ENSG00000183813(see-also) - - - figure legend:Fig. 4a|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/12/18 2019/01/30 rogid:p2UBpMzVG+A8AV7UCH4jYTsoPF89606 - intact-crc:0819B2C21C72A508 false - biotin tag:?-? - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:P17275 intact:EBI-10046032 intact:EBI-748062|uniprotkb:Q96GH3|ensembl:ENSP00000303315 - psi-mi:junb_human(display_long)|uniprotkb:JUNB(gene name)|psi-mi:JUNB(display_short) psi-mi:ccr4_human_ap1-site_dna-probe(display_short)|psi-mi:EBI-10046032(display_long) psi-mi:"MI:0892"(solid phase assay) Nakayama et al. (2008) pubmed:18071306|imex:IM-23609 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-10046278|imex:IM-23609-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0319"(deoxyribonucleic acid) refseq:NP_002220.1|ensembl:ENSG00000171223(gene)|ensembl:ENST00000302754(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0033687"(osteoblast proliferation)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029822|mint:P17275|reactome:R-HSA-2173796|reactome:R-HSA-6785807|reactome:R-HSA-9031628|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|dip:DIP-1052N ensembl:ENSG00000183813(see-also) - - - figure legend:Fig. 4a|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/12/18 2014/12/18 rogid:p2UBpMzVG+A8AV7UCH4jYTsoPF89606 - intact-crc:CFA3CC5A8D2E99D5 false - biotin tag:?-? - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) intact:EBI-10046032 intact:EBI-10046032 - - psi-mi:ccr4_human_ap1-site_dna-probe(display_short)|psi-mi:EBI-10046032(display_long) psi-mi:ccr4_human_ap1-site_dna-probe(display_short)|psi-mi:EBI-10046032(display_long) psi-mi:"MI:0892"(solid phase assay) Nakayama et al. (2008) pubmed:18071306|imex:IM-23609 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10046173|imex:IM-23609-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0319"(deoxyribonucleic acid) psi-mi:"MI:0319"(deoxyribonucleic acid) ensembl:ENSG00000183813(see-also) ensembl:ENSG00000183813(see-also) - - - figure legend:Fig. 4a|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/12/18 2014/12/18 - - intact-crc:7C20265175B4B802 false biotin tag:?-? mutation decreasing interaction:10-10,12-12 - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) intact:EBI-10046032 uniprotkb:P17275 - intact:EBI-748062|uniprotkb:Q96GH3|ensembl:ENSP00000303315 psi-mi:ccr4_human_ap1-site_dna-probe(display_short)|psi-mi:EBI-10046032(display_long) psi-mi:junb_human(display_long)|uniprotkb:JUNB(gene name)|psi-mi:JUNB(display_short) psi-mi:"MI:0892"(solid phase assay) Nakayama et al. (2008) pubmed:18071306|imex:IM-23609 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10046173|imex:IM-23609-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0319"(deoxyribonucleic acid) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183813(see-also) refseq:NP_002220.1|ensembl:ENSG00000171223(gene)|ensembl:ENST00000302754(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0033687"(osteoblast proliferation)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029822|mint:P17275|reactome:R-HSA-2173796|reactome:R-HSA-6785807|reactome:R-HSA-9031628|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|dip:DIP-1052N - - - figure legend:Fig. 4a|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/12/18 2014/12/18 - rogid:p2UBpMzVG+A8AV7UCH4jYTsoPF89606 intact-crc:7C20265175B4B802 false biotin tag:?-? - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) intact:EBI-10046032 uniprotkb:P17275 - intact:EBI-748062|uniprotkb:Q96GH3|ensembl:ENSP00000303315 psi-mi:ccr4_human_ap1-site_dna-probe(display_short)|psi-mi:EBI-10046032(display_long) psi-mi:junb_human(display_long)|uniprotkb:JUNB(gene name)|psi-mi:JUNB(display_short) psi-mi:"MI:0892"(solid phase assay) Nakayama et al. (2008) pubmed:18071306|imex:IM-23609 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10046284|imex:IM-23609-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0319"(deoxyribonucleic acid) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183813(see-also) refseq:NP_002220.1|ensembl:ENSG00000171223(gene)|ensembl:ENST00000302754(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0033687"(osteoblast proliferation)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029822|mint:P17275|reactome:R-HSA-2173796|reactome:R-HSA-6785807|reactome:R-HSA-9031628|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|dip:DIP-1052N - - - figure legend:Fig. 4a|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/12/18 2014/12/18 - rogid:p2UBpMzVG+A8AV7UCH4jYTsoPF89606 intact-crc:BE60238E222CC87C false biotin tag:?-? - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) intact:EBI-10046032 intact:EBI-10046032 - - psi-mi:ccr4_human_ap1-site_dna-probe(display_short)|psi-mi:EBI-10046032(display_long) psi-mi:ccr4_human_ap1-site_dna-probe(display_short)|psi-mi:EBI-10046032(display_long) psi-mi:"MI:0892"(solid phase assay) Nakayama et al. (2008) pubmed:18071306|imex:IM-23609 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10046284|imex:IM-23609-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0319"(deoxyribonucleic acid) psi-mi:"MI:0319"(deoxyribonucleic acid) ensembl:ENSG00000183813(see-also) ensembl:ENSG00000183813(see-also) - - - figure legend:Fig. 4a|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/12/18 2014/12/18 - - intact-crc:BE60238E222CC87C false biotin tag:?-? mutation decreasing interaction:10-10,12-12 - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:P17535 intact:EBI-10046032 intact:EBI-2682803|uniprotkb:Q53EK9|ensembl:ENSP00000252818 - psi-mi:jund_human(display_long)|uniprotkb:JUND(gene name)|psi-mi:JUND(display_short) psi-mi:ccr4_human_ap1-site_dna-probe(display_short)|psi-mi:EBI-10046032(display_long) psi-mi:"MI:0892"(solid phase assay) Nakayama et al. (2008) pubmed:18071306|imex:IM-23609 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-10046294|imex:IM-23609-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0319"(deoxyribonucleic acid) refseq:NP_001273897.1|refseq:NP_005345.3|ensembl:ENSG00000130522(gene)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043032"(positive regulation of macrophage activation)|ensembl:ENST00000252818(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|interpro:IPR029823|mint:P17535|rcsb pdb:3U86|rcsb pdb:5VPA|rcsb pdb:5VPB|rcsb pdb:5VPC|rcsb pdb:5VPD|rcsb pdb:5VPE|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|rcsb pdb:5VPF|reactome:R-HSA-9018519|reactome:R-HSA-9031628|go:"GO:0002076"(osteoblast development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007568"(aging)|dip:DIP-1053N ensembl:ENSG00000183813(see-also) - - - figure legend:Fig. 4a|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/12/18 2014/12/18 rogid:npmTGULvlKr4hC8HfmK19GUopf49606 - intact-crc:FED52A8084A76DC4 false - biotin tag:?-? - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:P17535 intact:EBI-10046032 intact:EBI-2682803|uniprotkb:Q53EK9|ensembl:ENSP00000252818 - psi-mi:jund_human(display_long)|uniprotkb:JUND(gene name)|psi-mi:JUND(display_short) psi-mi:ccr4_human_ap1-site_dna-probe(display_short)|psi-mi:EBI-10046032(display_long) psi-mi:"MI:0892"(solid phase assay) Nakayama et al. (2008) pubmed:18071306|imex:IM-23609 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-10046183|imex:IM-23609-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0319"(deoxyribonucleic acid) refseq:NP_001273897.1|refseq:NP_005345.3|ensembl:ENSG00000130522(gene)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043032"(positive regulation of macrophage activation)|ensembl:ENST00000252818(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|interpro:IPR029823|mint:P17535|rcsb pdb:3U86|rcsb pdb:5VPA|rcsb pdb:5VPB|rcsb pdb:5VPC|rcsb pdb:5VPD|rcsb pdb:5VPE|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|rcsb pdb:5VPF|reactome:R-HSA-9018519|reactome:R-HSA-9031628|go:"GO:0002076"(osteoblast development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007568"(aging)|dip:DIP-1053N ensembl:ENSG00000183813(see-also) - - - figure legend:Fig. 4a|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/12/18 2019/01/30 rogid:npmTGULvlKr4hC8HfmK19GUopf49606 - intact-crc:396F541815FB5119 false - biotin tag:?-? - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) intact:EBI-10046032 uniprotkb:P17535 - intact:EBI-2682803|uniprotkb:Q53EK9|ensembl:ENSP00000252818 psi-mi:ccr4_human_ap1-site_dna-probe(display_short)|psi-mi:EBI-10046032(display_long) psi-mi:jund_human(display_long)|uniprotkb:JUND(gene name)|psi-mi:JUND(display_short) psi-mi:"MI:0892"(solid phase assay) Nakayama et al. (2008) pubmed:18071306|imex:IM-23609 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10046189|imex:IM-23609-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0319"(deoxyribonucleic acid) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183813(see-also) refseq:NP_001273897.1|refseq:NP_005345.3|ensembl:ENSG00000130522(gene)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043032"(positive regulation of macrophage activation)|ensembl:ENST00000252818(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|interpro:IPR029823|mint:P17535|rcsb pdb:3U86|rcsb pdb:5VPA|rcsb pdb:5VPB|rcsb pdb:5VPC|rcsb pdb:5VPD|rcsb pdb:5VPE|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|rcsb pdb:5VPF|reactome:R-HSA-9018519|reactome:R-HSA-9031628|go:"GO:0002076"(osteoblast development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007568"(aging)|dip:DIP-1053N - - - figure legend:Fig. 4a|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/12/18 2014/12/18 - rogid:npmTGULvlKr4hC8HfmK19GUopf49606 intact-crc:DCC17777D37270AF false biotin tag:?-? - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) intact:EBI-10046032 intact:EBI-10046032 - - psi-mi:ccr4_human_ap1-site_dna-probe(display_short)|psi-mi:EBI-10046032(display_long) psi-mi:ccr4_human_ap1-site_dna-probe(display_short)|psi-mi:EBI-10046032(display_long) psi-mi:"MI:0892"(solid phase assay) Nakayama et al. (2008) pubmed:18071306|imex:IM-23609 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10046189|imex:IM-23609-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0319"(deoxyribonucleic acid) psi-mi:"MI:0319"(deoxyribonucleic acid) ensembl:ENSG00000183813(see-also) ensembl:ENSG00000183813(see-also) - - - figure legend:Fig. 4a|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/12/18 2014/12/18 - - intact-crc:DCC17777D37270AF false biotin tag:?-? mutation disrupting interaction:10-10,12-12 - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) intact:EBI-10046032 uniprotkb:P17535 - intact:EBI-2682803|uniprotkb:Q53EK9|ensembl:ENSP00000252818 psi-mi:ccr4_human_ap1-site_dna-probe(display_short)|psi-mi:EBI-10046032(display_long) psi-mi:jund_human(display_long)|uniprotkb:JUND(gene name)|psi-mi:JUND(display_short) psi-mi:"MI:0892"(solid phase assay) Nakayama et al. (2008) pubmed:18071306|imex:IM-23609 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10046325|imex:IM-23609-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0319"(deoxyribonucleic acid) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183813(see-also) refseq:NP_001273897.1|refseq:NP_005345.3|ensembl:ENSG00000130522(gene)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043032"(positive regulation of macrophage activation)|ensembl:ENST00000252818(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|interpro:IPR029823|mint:P17535|rcsb pdb:3U86|rcsb pdb:5VPA|rcsb pdb:5VPB|rcsb pdb:5VPC|rcsb pdb:5VPD|rcsb pdb:5VPE|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|rcsb pdb:5VPF|reactome:R-HSA-9018519|reactome:R-HSA-9031628|go:"GO:0002076"(osteoblast development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007568"(aging)|dip:DIP-1053N - - - figure legend:Fig. 4a|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/12/18 2014/12/18 - rogid:npmTGULvlKr4hC8HfmK19GUopf49606 intact-crc:B2B5FD6C43DEAC30 false biotin tag:?-? - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) intact:EBI-10046032 intact:EBI-10046032 - - psi-mi:ccr4_human_ap1-site_dna-probe(display_short)|psi-mi:EBI-10046032(display_long) psi-mi:ccr4_human_ap1-site_dna-probe(display_short)|psi-mi:EBI-10046032(display_long) psi-mi:"MI:0892"(solid phase assay) Nakayama et al. (2008) pubmed:18071306|imex:IM-23609 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10046325|imex:IM-23609-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0319"(deoxyribonucleic acid) psi-mi:"MI:0319"(deoxyribonucleic acid) ensembl:ENSG00000183813(see-also) ensembl:ENSG00000183813(see-also) - - - figure legend:Fig. 4a|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/12/18 2014/12/18 - - intact-crc:B2B5FD6C43DEAC30 false biotin tag:?-? mutation disrupting interaction:10-10,12-12 - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody)