#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P0ABH9 uniprotkb:P0A6G7 intact:EBI-546140|uniprotkb:P15716|uniprotkb:P77686|ensemblbacteria:AAC73969|ensemblbacteria:BAA35601 intact:EBI-370625|uniprotkb:P19245|uniprotkb:Q2MBY9|ensemblbacteria:AAC73540|ensemblbacteria:BAE76217 psi-mi:clpa_ecoli(display_long)|uniprotkb:clpA(gene name)|psi-mi:clpA(display_short)|uniprotkb:lopD(gene name synonym)|uniprotkb:b0882(locus name)|uniprotkb:JW0866(locus name) psi-mi:clpp_ecoli(display_long)|uniprotkb:clpP(gene name)|psi-mi:clpP(display_short)|uniprotkb:lopP(gene name synonym)|uniprotkb:Endopeptidase Clp(gene name synonym)|uniprotkb:Caseinolytic protease(gene name synonym)|uniprotkb:Protease Ti(gene name synonym)|uniprotkb:Heat shock protein F21.5(gene name synonym)|uniprotkb:b0437(locus name)|uniprotkb:JW0427(locus name) psi-mi:"MI:0071"(molecular sieving) Maurizi et al. (1991) imex:IM-22973|pubmed:1783205 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-9674634|imex:IM-22973-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1MBX|rcsb pdb:1MG9|rcsb pdb:1R6B|rcsb pdb:1R6C|rcsb pdb:1R6O|rcsb pdb:1R6Q|rcsb pdb:5OFO|rcsb pdb:5OG1|rcsb pdb:6UQE|rcsb pdb:6UQO|rcsb pdb:6W1Z|rcsb pdb:6W20|rcsb pdb:6W21|rcsb pdb:6W22|rcsb pdb:6W23|rcsb pdb:6W24|ensemblbacteria:AAC73969(transcript)|ensemblbacteria:b0882(gene)|ensemblbacteria:BAA35601(gene)|ensemblbacteria:BAA35601(transcript)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0043335"(protein unfolding)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR004176(Clp, N-terminal)|interpro:IPR013461(ATP-dependent Clp protease ATP-binding subunit clpA)|interpro:IPR018368|interpro:IPR019489|interpro:IPR027417|interpro:IPR028299|interpro:IPR036628|interpro:IPR041546|rcsb pdb:1K6K|rcsb pdb:1KSF|rcsb pdb:1LZW|rcsb pdb:1MBU|rcsb pdb:1MBV|refseq:NP_415403.1|refseq:WP_000934041.1|dip:DIP-35409N refseq:WP_000122253.1|refseq:NP_414971.1|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0009266"(response to temperature stimulus)|go:"GO:0009314"(response to radiation)|go:"GO:0009368"(endopeptidase Clp complex)|go:"GO:0009376"(HslUV protease complex)|go:"GO:0009408"(response to heat)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0051117"(ATPase binding)|interpro:IPR001907(Peptidase S14, ClpP)|interpro:IPR018215|interpro:IPR023562|interpro:IPR029045|interpro:IPR033135|rcsb pdb:1TYF|rcsb pdb:1YG6|rcsb pdb:1YG8|rcsb pdb:2FZS|rcsb pdb:3HLN|rcsb pdb:3MT6|rcsb pdb:6NB1|rcsb pdb:6PO1|rcsb pdb:6PO3|rcsb pdb:6POD|rcsb pdb:6POS|rcsb pdb:6PPE|rcsb pdb:6UQE|rcsb pdb:6UQO|rcsb pdb:6W1Z|rcsb pdb:6W20|rcsb pdb:6W21|rcsb pdb:6WR2|rcsb pdb:6WRF|rcsb pdb:6WSG|ensemblbacteria:AAC73540(transcript)|ensemblbacteria:b0437(gene)|ensemblbacteria:BAE76217(gene)|ensemblbacteria:BAE76217(transcript)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|dip:DIP-31838N - - - comment:"Interaction only occurred in the presence of AMPPNP (adenosine 5'-[beta-gamma-imido]triphosphate)"|figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/07/18 2014/10/16 rogid:qgKZjSma6WZIUf0i16Rt+DvXVsM83333 rogid:M9znviYWdujU3uleyh6186V2r7I83333 intact-crc:90D38F885AEBA903|rigid:Fko2yFDvXwOM7k5myogo5apTTic false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)