#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q96BZ9 uniprotkb:P27958-PRO_0000037576 intact:EBI-9254454|uniprotkb:A8K6I3|uniprotkb:Q5JWQ7|uniprotkb:Q6ZSY8|uniprotkb:Q96NE1|uniprotkb:Q9BYM7|uniprotkb:Q9H140|uniprotkb:B9A6M1|ensembl:ENSP00000346139|ensembl:ENSP00000432280|ensembl:ENSP00000504904|ensembl:ENSP00000505500|ensembl:ENSP00000505557|ensembl:ENSP00000506012|ensembl:ENSP00000506122|ensembl:ENSP00000506155|ensembl:ENSP00000506231|ensembl:ENSP00000506278 intact:EBI-8753518 psi-mi:tbc20_human(display_long)|uniprotkb:TBC1D20(gene name)|psi-mi:TBC1D20(display_short)|uniprotkb:C20orf140(gene name synonym) psi-mi:p27958-pro_0000037576(display_long) psi-mi:"MI:0663"(confocal microscopy) Sklan et al. (2007) imex:IM-22273|pubmed:17686842 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:1335"(HPIDb) intact:EBI-9342597|imex:IM-22273-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_653229.1|refseq:XP_005260718.1|ensembl:ENSG00000125875(gene)|ensembl:ENST00000354200(transcript)|ensembl:ENST00000461304(transcript)|ensembl:ENST00000679741(transcript)|ensembl:ENST00000679944(transcript)|ensembl:ENST00000680106(transcript)|ensembl:ENST00000680284(transcript)|ensembl:ENST00000680792(transcript)|ensembl:ENST00000681539(transcript)|ensembl:ENST00000681636(transcript)|ensembl:ENST00000681742(transcript)|go:"GO:0001675"(acrosome assembly)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0019068"(virion assembly)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:1902953"(positive regulation of ER to Golgi vesicle-mediated transport)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|mint:Q96BZ9|rcsb pdb:4HL4|rcsb pdb:4HLQ|reactome:R-HSA-204005|reactome:R-HSA-8854214 intact:EBI-706378(chain-parent) go:"GO:0030430"(host cell cytoplasm) - chain-seq-start:1973|chain-seq-end:2420 figure legend:Fig. 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2014/03/10 2014/10/16 rogid:COELqhy6DNf7WUeC1HPH1w7M4AE9606 rogid:QUtsxvdJhyaJg2Xu4JFrW5Tay2A63746 intact-crc:3F253290650797DB|rigid:67JLjS8gt+n2dx4LfZrZ/kVoiH8 false green fluorescent protein tag:n-n red fluorescent protein tag:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P27958-PRO_0000037576 uniprotkb:Q96BZ9 intact:EBI-8753518 intact:EBI-9254454|uniprotkb:A8K6I3|uniprotkb:Q5JWQ7|uniprotkb:Q6ZSY8|uniprotkb:Q96NE1|uniprotkb:Q9BYM7|uniprotkb:Q9H140|uniprotkb:B9A6M1|ensembl:ENSP00000346139|ensembl:ENSP00000432280|ensembl:ENSP00000504904|ensembl:ENSP00000505500|ensembl:ENSP00000505557|ensembl:ENSP00000506012|ensembl:ENSP00000506122|ensembl:ENSP00000506155|ensembl:ENSP00000506231|ensembl:ENSP00000506278 psi-mi:p27958-pro_0000037576(display_long) psi-mi:tbc20_human(display_long)|uniprotkb:TBC1D20(gene name)|psi-mi:TBC1D20(display_short)|uniprotkb:C20orf140(gene name synonym) psi-mi:"MI:0018"(two hybrid) Sklan et al. (2007) imex:IM-22273|pubmed:17686842 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9255670|imex:IM-22273-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_653229.1|refseq:XP_005260718.1|ensembl:ENSG00000125875(gene)|ensembl:ENST00000354200(transcript)|ensembl:ENST00000461304(transcript)|ensembl:ENST00000679741(transcript)|ensembl:ENST00000679944(transcript)|ensembl:ENST00000680106(transcript)|ensembl:ENST00000680284(transcript)|ensembl:ENST00000680792(transcript)|ensembl:ENST00000681539(transcript)|ensembl:ENST00000681636(transcript)|ensembl:ENST00000681742(transcript)|go:"GO:0001675"(acrosome assembly)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0019068"(virion assembly)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:1902953"(positive regulation of ER to Golgi vesicle-mediated transport)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|mint:Q96BZ9|rcsb pdb:4HL4|rcsb pdb:4HLQ|reactome:R-HSA-204005|reactome:R-HSA-8854214 - chain-seq-start:1973|chain-seq-end:2420 - figure legend:No figure|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/03/10 2014/10/16 rogid:QUtsxvdJhyaJg2Xu4JFrW5Tay2A63746 rogid:COELqhy6DNf7WUeC1HPH1w7M4AE9606 intact-crc:00B721909AD84D26|rigid:67JLjS8gt+n2dx4LfZrZ/kVoiH8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96BZ9 uniprotkb:P27958-PRO_0000037576 intact:EBI-9254454|uniprotkb:A8K6I3|uniprotkb:Q5JWQ7|uniprotkb:Q6ZSY8|uniprotkb:Q96NE1|uniprotkb:Q9BYM7|uniprotkb:Q9H140|uniprotkb:B9A6M1|ensembl:ENSP00000346139|ensembl:ENSP00000432280|ensembl:ENSP00000504904|ensembl:ENSP00000505500|ensembl:ENSP00000505557|ensembl:ENSP00000506012|ensembl:ENSP00000506122|ensembl:ENSP00000506155|ensembl:ENSP00000506231|ensembl:ENSP00000506278 intact:EBI-8753518 psi-mi:tbc20_human(display_long)|uniprotkb:TBC1D20(gene name)|psi-mi:TBC1D20(display_short)|uniprotkb:C20orf140(gene name synonym) psi-mi:p27958-pro_0000037576(display_long) psi-mi:"MI:0018"(two hybrid) Sklan et al. (2007) imex:IM-22273|pubmed:17686842 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9342573|imex:IM-22273-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_653229.1|refseq:XP_005260718.1|ensembl:ENSG00000125875(gene)|ensembl:ENST00000354200(transcript)|ensembl:ENST00000461304(transcript)|ensembl:ENST00000679741(transcript)|ensembl:ENST00000679944(transcript)|ensembl:ENST00000680106(transcript)|ensembl:ENST00000680284(transcript)|ensembl:ENST00000680792(transcript)|ensembl:ENST00000681539(transcript)|ensembl:ENST00000681636(transcript)|ensembl:ENST00000681742(transcript)|go:"GO:0001675"(acrosome assembly)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0019068"(virion assembly)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:1902953"(positive regulation of ER to Golgi vesicle-mediated transport)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|mint:Q96BZ9|rcsb pdb:4HL4|rcsb pdb:4HLQ|reactome:R-HSA-204005|reactome:R-HSA-8854214 intact:EBI-706378(chain-parent) - - chain-seq-start:1973|chain-seq-end:2420 figure legend:Fig. 1A|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/03/10 2014/10/16 rogid:COELqhy6DNf7WUeC1HPH1w7M4AE9606 rogid:QUtsxvdJhyaJg2Xu4JFrW5Tay2A63746 intact-crc:E0169E0C9AAAE95F|rigid:67JLjS8gt+n2dx4LfZrZ/kVoiH8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037576 uniprotkb:Q96BZ9 intact:EBI-8753518 intact:EBI-9254454|uniprotkb:A8K6I3|uniprotkb:Q5JWQ7|uniprotkb:Q6ZSY8|uniprotkb:Q96NE1|uniprotkb:Q9BYM7|uniprotkb:Q9H140|uniprotkb:B9A6M1|ensembl:ENSP00000346139|ensembl:ENSP00000432280|ensembl:ENSP00000504904|ensembl:ENSP00000505500|ensembl:ENSP00000505557|ensembl:ENSP00000506012|ensembl:ENSP00000506122|ensembl:ENSP00000506155|ensembl:ENSP00000506231|ensembl:ENSP00000506278 psi-mi:p27958-pro_0000037576(display_long) psi-mi:tbc20_human(display_long)|uniprotkb:TBC1D20(gene name)|psi-mi:TBC1D20(display_short)|uniprotkb:C20orf140(gene name synonym) psi-mi:"MI:0018"(two hybrid) Sklan et al. (2007) imex:IM-22273|pubmed:17686842 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9255684|imex:IM-22273-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_653229.1|refseq:XP_005260718.1|ensembl:ENSG00000125875(gene)|ensembl:ENST00000354200(transcript)|ensembl:ENST00000461304(transcript)|ensembl:ENST00000679741(transcript)|ensembl:ENST00000679944(transcript)|ensembl:ENST00000680106(transcript)|ensembl:ENST00000680284(transcript)|ensembl:ENST00000680792(transcript)|ensembl:ENST00000681539(transcript)|ensembl:ENST00000681636(transcript)|ensembl:ENST00000681742(transcript)|go:"GO:0001675"(acrosome assembly)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0019068"(virion assembly)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:1902953"(positive regulation of ER to Golgi vesicle-mediated transport)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|mint:Q96BZ9|rcsb pdb:4HL4|rcsb pdb:4HLQ|reactome:R-HSA-204005|reactome:R-HSA-8854214 - chain-seq-start:1973|chain-seq-end:2420 - figure legend:Fig. 1B|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/03/10 2014/10/16 rogid:QUtsxvdJhyaJg2Xu4JFrW5Tay2A63746 rogid:COELqhy6DNf7WUeC1HPH1w7M4AE9606 intact-crc:A27BD605AD175B1A|rigid:67JLjS8gt+n2dx4LfZrZ/kVoiH8 false sufficient binding region:1-100 sufficient binding region:269-403 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96BZ9 uniprotkb:P27958-PRO_0000037576 intact:EBI-9254454|uniprotkb:A8K6I3|uniprotkb:Q5JWQ7|uniprotkb:Q6ZSY8|uniprotkb:Q96NE1|uniprotkb:Q9BYM7|uniprotkb:Q9H140|uniprotkb:B9A6M1|ensembl:ENSP00000346139|ensembl:ENSP00000432280|ensembl:ENSP00000504904|ensembl:ENSP00000505500|ensembl:ENSP00000505557|ensembl:ENSP00000506012|ensembl:ENSP00000506122|ensembl:ENSP00000506155|ensembl:ENSP00000506231|ensembl:ENSP00000506278 intact:EBI-8753518 psi-mi:tbc20_human(display_long)|uniprotkb:TBC1D20(gene name)|psi-mi:TBC1D20(display_short)|uniprotkb:C20orf140(gene name synonym) psi-mi:p27958-pro_0000037576(display_long) psi-mi:"MI:0018"(two hybrid) Sklan et al. (2007) imex:IM-22273|pubmed:17686842 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9342577|imex:IM-22273-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_653229.1|refseq:XP_005260718.1|ensembl:ENSG00000125875(gene)|ensembl:ENST00000354200(transcript)|ensembl:ENST00000461304(transcript)|ensembl:ENST00000679741(transcript)|ensembl:ENST00000679944(transcript)|ensembl:ENST00000680106(transcript)|ensembl:ENST00000680284(transcript)|ensembl:ENST00000680792(transcript)|ensembl:ENST00000681539(transcript)|ensembl:ENST00000681636(transcript)|ensembl:ENST00000681742(transcript)|go:"GO:0001675"(acrosome assembly)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0019068"(virion assembly)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:1902953"(positive regulation of ER to Golgi vesicle-mediated transport)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|mint:Q96BZ9|rcsb pdb:4HL4|rcsb pdb:4HLQ|reactome:R-HSA-204005|reactome:R-HSA-8854214 intact:EBI-706378(chain-parent) - - chain-seq-start:1973|chain-seq-end:2420 figure legend:Fig. 1A|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/03/10 2014/10/16 rogid:COELqhy6DNf7WUeC1HPH1w7M4AE9606 rogid:QUtsxvdJhyaJg2Xu4JFrW5Tay2A63746 intact-crc:C4D06E155C00B834|rigid:67JLjS8gt+n2dx4LfZrZ/kVoiH8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037576 uniprotkb:Q96BZ9 intact:EBI-8753518 intact:EBI-9254454|uniprotkb:A8K6I3|uniprotkb:Q5JWQ7|uniprotkb:Q6ZSY8|uniprotkb:Q96NE1|uniprotkb:Q9BYM7|uniprotkb:Q9H140|uniprotkb:B9A6M1|ensembl:ENSP00000346139|ensembl:ENSP00000432280|ensembl:ENSP00000504904|ensembl:ENSP00000505500|ensembl:ENSP00000505557|ensembl:ENSP00000506012|ensembl:ENSP00000506122|ensembl:ENSP00000506155|ensembl:ENSP00000506231|ensembl:ENSP00000506278 psi-mi:p27958-pro_0000037576(display_long) psi-mi:tbc20_human(display_long)|uniprotkb:TBC1D20(gene name)|psi-mi:TBC1D20(display_short)|uniprotkb:C20orf140(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Sklan et al. (2007) imex:IM-22273|pubmed:17686842 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9255700|imex:IM-22273-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_653229.1|refseq:XP_005260718.1|ensembl:ENSG00000125875(gene)|ensembl:ENST00000354200(transcript)|ensembl:ENST00000461304(transcript)|ensembl:ENST00000679741(transcript)|ensembl:ENST00000679944(transcript)|ensembl:ENST00000680106(transcript)|ensembl:ENST00000680284(transcript)|ensembl:ENST00000680792(transcript)|ensembl:ENST00000681539(transcript)|ensembl:ENST00000681636(transcript)|ensembl:ENST00000681742(transcript)|go:"GO:0001675"(acrosome assembly)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0019068"(virion assembly)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:1902953"(positive regulation of ER to Golgi vesicle-mediated transport)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|mint:Q96BZ9|rcsb pdb:4HL4|rcsb pdb:4HLQ|reactome:R-HSA-204005|reactome:R-HSA-8854214 - chain-seq-start:1973|chain-seq-end:2420 - figure legend:Fig. 1C|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2014/03/10 2014/10/16 rogid:QUtsxvdJhyaJg2Xu4JFrW5Tay2A63746 rogid:COELqhy6DNf7WUeC1HPH1w7M4AE9606 intact-crc:E9D0FF8AFFB17917|rigid:67JLjS8gt+n2dx4LfZrZ/kVoiH8 false - flag tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P27958-PRO_0000037576 uniprotkb:Q96BZ9 intact:EBI-8753518 intact:EBI-9254454|uniprotkb:A8K6I3|uniprotkb:Q5JWQ7|uniprotkb:Q6ZSY8|uniprotkb:Q96NE1|uniprotkb:Q9BYM7|uniprotkb:Q9H140|uniprotkb:B9A6M1|ensembl:ENSP00000346139|ensembl:ENSP00000432280|ensembl:ENSP00000504904|ensembl:ENSP00000505500|ensembl:ENSP00000505557|ensembl:ENSP00000506012|ensembl:ENSP00000506122|ensembl:ENSP00000506155|ensembl:ENSP00000506231|ensembl:ENSP00000506278 psi-mi:p27958-pro_0000037576(display_long) psi-mi:tbc20_human(display_long)|uniprotkb:TBC1D20(gene name)|psi-mi:TBC1D20(display_short)|uniprotkb:C20orf140(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Sklan et al. (2007) imex:IM-22273|pubmed:17686842 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:1335"(HPIDb) intact:EBI-9255762|imex:IM-22273-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_653229.1|refseq:XP_005260718.1|ensembl:ENSG00000125875(gene)|ensembl:ENST00000354200(transcript)|ensembl:ENST00000461304(transcript)|ensembl:ENST00000679741(transcript)|ensembl:ENST00000679944(transcript)|ensembl:ENST00000680106(transcript)|ensembl:ENST00000680284(transcript)|ensembl:ENST00000680792(transcript)|ensembl:ENST00000681539(transcript)|ensembl:ENST00000681636(transcript)|ensembl:ENST00000681742(transcript)|go:"GO:0001675"(acrosome assembly)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0019068"(virion assembly)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:1902953"(positive regulation of ER to Golgi vesicle-mediated transport)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|mint:Q96BZ9|rcsb pdb:4HL4|rcsb pdb:4HLQ|reactome:R-HSA-204005|reactome:R-HSA-8854214 go:"GO:0030430"(host cell cytoplasm) chain-seq-start:1973|chain-seq-end:2420 - figure legend:Fig. 2C|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2014/03/10 2014/10/16 rogid:QUtsxvdJhyaJg2Xu4JFrW5Tay2A63746 rogid:COELqhy6DNf7WUeC1HPH1w7M4AE9606 intact-crc:EC82734D4792A577|rigid:67JLjS8gt+n2dx4LfZrZ/kVoiH8 false ha tag:c-c green fluorescent protein tag:n-n - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q96BZ9 uniprotkb:P27958-PRO_0000037576 intact:EBI-9254454|uniprotkb:A8K6I3|uniprotkb:Q5JWQ7|uniprotkb:Q6ZSY8|uniprotkb:Q96NE1|uniprotkb:Q9BYM7|uniprotkb:Q9H140|uniprotkb:B9A6M1|ensembl:ENSP00000346139|ensembl:ENSP00000432280|ensembl:ENSP00000504904|ensembl:ENSP00000505500|ensembl:ENSP00000505557|ensembl:ENSP00000506012|ensembl:ENSP00000506122|ensembl:ENSP00000506155|ensembl:ENSP00000506231|ensembl:ENSP00000506278 intact:EBI-8753518 psi-mi:tbc20_human(display_long)|uniprotkb:TBC1D20(gene name)|psi-mi:TBC1D20(display_short)|uniprotkb:C20orf140(gene name synonym) psi-mi:p27958-pro_0000037576(display_long) psi-mi:"MI:0663"(confocal microscopy) Sklan et al. (2007) imex:IM-22273|pubmed:17686842 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:1335"(HPIDb) intact:EBI-9255750|imex:IM-22273-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_653229.1|refseq:XP_005260718.1|ensembl:ENSG00000125875(gene)|ensembl:ENST00000354200(transcript)|ensembl:ENST00000461304(transcript)|ensembl:ENST00000679741(transcript)|ensembl:ENST00000679944(transcript)|ensembl:ENST00000680106(transcript)|ensembl:ENST00000680284(transcript)|ensembl:ENST00000680792(transcript)|ensembl:ENST00000681539(transcript)|ensembl:ENST00000681636(transcript)|ensembl:ENST00000681742(transcript)|go:"GO:0001675"(acrosome assembly)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0019068"(virion assembly)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:1902953"(positive regulation of ER to Golgi vesicle-mediated transport)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|mint:Q96BZ9|rcsb pdb:4HL4|rcsb pdb:4HLQ|reactome:R-HSA-204005|reactome:R-HSA-8854214 intact:EBI-706378(chain-parent) go:"GO:0030430"(host cell cytoplasm) - chain-seq-start:1973|chain-seq-end:2420 figure legend:Fig. 2B|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2014/03/10 2014/10/16 rogid:COELqhy6DNf7WUeC1HPH1w7M4AE9606 rogid:QUtsxvdJhyaJg2Xu4JFrW5Tay2A63746 intact-crc:007C6D48140C6697|rigid:67JLjS8gt+n2dx4LfZrZ/kVoiH8 false green fluorescent protein tag:n-n - - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q96BZ9 uniprotkb:P27958-PRO_0000037576 intact:EBI-9254454|uniprotkb:A8K6I3|uniprotkb:Q5JWQ7|uniprotkb:Q6ZSY8|uniprotkb:Q96NE1|uniprotkb:Q9BYM7|uniprotkb:Q9H140|uniprotkb:B9A6M1|ensembl:ENSP00000346139|ensembl:ENSP00000432280|ensembl:ENSP00000504904|ensembl:ENSP00000505500|ensembl:ENSP00000505557|ensembl:ENSP00000506012|ensembl:ENSP00000506122|ensembl:ENSP00000506155|ensembl:ENSP00000506231|ensembl:ENSP00000506278 intact:EBI-8753518 psi-mi:tbc20_human(display_long)|uniprotkb:TBC1D20(gene name)|psi-mi:TBC1D20(display_short)|uniprotkb:C20orf140(gene name synonym) psi-mi:p27958-pro_0000037576(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sklan et al. (2007) imex:IM-22273|pubmed:17686842 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9255730|imex:IM-22273-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_653229.1|refseq:XP_005260718.1|ensembl:ENSG00000125875(gene)|ensembl:ENST00000354200(transcript)|ensembl:ENST00000461304(transcript)|ensembl:ENST00000679741(transcript)|ensembl:ENST00000679944(transcript)|ensembl:ENST00000680106(transcript)|ensembl:ENST00000680284(transcript)|ensembl:ENST00000680792(transcript)|ensembl:ENST00000681539(transcript)|ensembl:ENST00000681636(transcript)|ensembl:ENST00000681742(transcript)|go:"GO:0001675"(acrosome assembly)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0019068"(virion assembly)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:1902953"(positive regulation of ER to Golgi vesicle-mediated transport)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|mint:Q96BZ9|rcsb pdb:4HL4|rcsb pdb:4HLQ|reactome:R-HSA-204005|reactome:R-HSA-8854214 intact:EBI-706378(chain-parent) - - chain-seq-start:1973|chain-seq-end:2420 figure legend:Fig. 1D|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/03/10 2014/10/16 rogid:COELqhy6DNf7WUeC1HPH1w7M4AE9606 rogid:QUtsxvdJhyaJg2Xu4JFrW5Tay2A63746 intact-crc:80E5D6B34A6BE631|rigid:67JLjS8gt+n2dx4LfZrZ/kVoiH8 false ha tag:n-n mutation disrupting interaction strength:8-8,12-12,19-19|flag tag:c-c|35s radiolabel:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography)