#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q10728 uniprotkb:O43293-2 intact:EBI-918263|uniprotkb:Q62937|uniprotkb:Q9WU33 intact:EBI-9691390 psi-mi:mypt1_rat(display_long)|uniprotkb:Ppp1r12a(gene name)|psi-mi:Ppp1r12a(display_short)|uniprotkb:Mbs(gene name synonym)|uniprotkb:Mypt1(gene name synonym)|uniprotkb:Myosin phosphatase-targeting subunit 1(gene name synonym)|uniprotkb:Protein phosphatase myosin-binding subunit(gene name synonym)|uniprotkb:MBSP(gene name synonym)|uniprotkb:Serine/threonine protein phosphatase PP1 smooth muscle regulatory subunit M110(gene name synonym)|uniprotkb:Protein phosphatase subunit 1M(gene name synonym) psi-mi:o43293-2(display_long)|uniprotkb:ZIPK-S(isoform synonym)|uniprotkb:DAPK3(gene name)|psi-mi:DAPK3(display_short)|uniprotkb:ZIPK(gene name synonym)|uniprotkb:DAP-like kinase(gene name synonym)|uniprotkb:MYPT1 kinase(gene name synonym)|uniprotkb:Zipper-interacting protein kinase(gene name synonym) psi-mi:"MI:0096"(pull down) Takamoto et al. (2006) pubmed:17126281|imex:IM-23035 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9691407|imex:IM-23035-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:620013|refseq:NP_446342.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031775|refseq:XP_006241377.1|interpro:IPR017401(Protein phosphatase 1, regulatory subunits 12A/B/C, eukaryote)|interpro:IPR036770|reactome:R-RNO-2565942|reactome:R-RNO-5625740|reactome:R-RNO-5627123|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0019208"(phosphatase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0031672"(A band)|go:"GO:0035507"(regulation of myosin-light-chain-phosphatase activity)|go:"GO:0035508"(positive regulation of myosin-light-chain-phosphatase activity)|go:"GO:0035690"|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043292"(contractile fiber)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0072357"(PTW/PP1 phosphatase complex) intact:EBI-77293(isoform-parent) - - isoform-comment:The internal splice site between exon 8 and the 3' UTR, which yields this truncated isoform, is non-canonical. figure legend:5A , B and C|comment:Phosphorylated and non-phosphorylated DAPK3/ZIPK interacted. Phosphorylation of PPP1R12A/Mypt1 decreases interaction.|antagonist:ATP|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/08/19 2014/10/16 rogid:C2cW3Wgc4JZQGtDsP1NgRkzEr1s10116 rogid:lKWgFqedO62zA+OIlGl4iy8fV309606 intact-crc:D16CB86902B82445|rigid:XttbYQf6Jw0QNcQ7P+AXd4LKqXs false phosphorylated residue:?-? glutathione s tranferase tag:?-?|necessary binding region:278-322 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O43293-2 - intact:EBI-9691390 - psi-mi:o43293-2(display_long)|uniprotkb:ZIPK-S(isoform synonym)|uniprotkb:DAPK3(gene name)|psi-mi:DAPK3(display_short)|uniprotkb:ZIPK(gene name synonym)|uniprotkb:DAP-like kinase(gene name synonym)|uniprotkb:MYPT1 kinase(gene name synonym)|uniprotkb:Zipper-interacting protein kinase(gene name synonym) - psi-mi:"MI:0424"(protein kinase assay) Takamoto et al. (2006) pubmed:17126281|imex:IM-23035 taxid:9606(human)|taxid:9606(Homo sapiens) - psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0486"(UniProt) intact:EBI-9699029|imex:IM-23035-7 - - psi-mi:"MI:0499"(unspecified role) - psi-mi:"MI:0898"(putative self) - psi-mi:"MI:0326"(protein) - intact:EBI-77293(isoform-parent) - go:"GO:0004672"(protein kinase activity)|go:"GO:0046777"(protein autophosphorylation) isoform-comment:The internal splice site between exon 8 and the 3' UTR, which yields this truncated isoform, is non-canonical. - figure legend:3A and 4A and B|antagonist:ATP|resulting-ptm:O43293-2 phosphores|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/08/19 2014/10/16 rogid:lKWgFqedO62zA+OIlGl4iy8fV309606 - intact-crc:3F53F8C0D5BCF979 false necessary binding region:278-322 - - - psi-mi:"MI:0833"(autoradiography) - uniprotkb:Q10728 uniprotkb:O43293-2 intact:EBI-918263|uniprotkb:Q62937|uniprotkb:Q9WU33 intact:EBI-9691390 psi-mi:mypt1_rat(display_long)|uniprotkb:Ppp1r12a(gene name)|psi-mi:Ppp1r12a(display_short)|uniprotkb:Mbs(gene name synonym)|uniprotkb:Mypt1(gene name synonym)|uniprotkb:Myosin phosphatase-targeting subunit 1(gene name synonym)|uniprotkb:Protein phosphatase myosin-binding subunit(gene name synonym)|uniprotkb:MBSP(gene name synonym)|uniprotkb:Serine/threonine protein phosphatase PP1 smooth muscle regulatory subunit M110(gene name synonym)|uniprotkb:Protein phosphatase subunit 1M(gene name synonym) psi-mi:o43293-2(display_long)|uniprotkb:ZIPK-S(isoform synonym)|uniprotkb:DAPK3(gene name)|psi-mi:DAPK3(display_short)|uniprotkb:ZIPK(gene name synonym)|uniprotkb:DAP-like kinase(gene name synonym)|uniprotkb:MYPT1 kinase(gene name synonym)|uniprotkb:Zipper-interacting protein kinase(gene name synonym) psi-mi:"MI:0424"(protein kinase assay) Takamoto et al. (2006) pubmed:17126281|imex:IM-23035 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0486"(UniProt) intact:EBI-9698961|imex:IM-23035-5 - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:620013|refseq:NP_446342.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031775|refseq:XP_006241377.1|interpro:IPR017401(Protein phosphatase 1, regulatory subunits 12A/B/C, eukaryote)|interpro:IPR036770|reactome:R-RNO-2565942|reactome:R-RNO-5625740|reactome:R-RNO-5627123|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0019208"(phosphatase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0031672"(A band)|go:"GO:0035507"(regulation of myosin-light-chain-phosphatase activity)|go:"GO:0035508"(positive regulation of myosin-light-chain-phosphatase activity)|go:"GO:0035690"|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043292"(contractile fiber)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0072357"(PTW/PP1 phosphatase complex) intact:EBI-77293(isoform-parent) go:"GO:0006468"(protein phosphorylation)|go:"GO:0004672"(protein kinase activity) - isoform-comment:The internal splice site between exon 8 and the 3' UTR, which yields this truncated isoform, is non-canonical. figure legend:2C and D|comment:Phosphorylated and non-phosphorylated DAPK3/ZIPK interacted. Phosphorylation of PPP1R12A/Mypt1 decreases interaction.|antagonist:ATP|resulting-ptm:Q10728 phosphores|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/08/19 2014/10/16 rogid:C2cW3Wgc4JZQGtDsP1NgRkzEr1s10116 rogid:lKWgFqedO62zA+OIlGl4iy8fV309606 intact-crc:3DF9BF0A0B73E9C4|rigid:XttbYQf6Jw0QNcQ7P+AXd4LKqXs false - - - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) uniprotkb:O43293-1 uniprotkb:Q10728 intact:EBI-9691444|ensembl:ENSP00000301264|ensembl:ENSP00000442973 intact:EBI-918263|uniprotkb:Q62937|uniprotkb:Q9WU33 psi-mi:o43293-1(display_long)|uniprotkb:ZIPK-L(isoform synonym)|uniprotkb:DAPK3(gene name)|psi-mi:DAPK3(display_short)|uniprotkb:ZIPK(gene name synonym)|uniprotkb:DAP-like kinase(gene name synonym)|uniprotkb:MYPT1 kinase(gene name synonym)|uniprotkb:Zipper-interacting protein kinase(gene name synonym) psi-mi:mypt1_rat(display_long)|uniprotkb:Ppp1r12a(gene name)|psi-mi:Ppp1r12a(display_short)|uniprotkb:Mbs(gene name synonym)|uniprotkb:Mypt1(gene name synonym)|uniprotkb:Myosin phosphatase-targeting subunit 1(gene name synonym)|uniprotkb:Protein phosphatase myosin-binding subunit(gene name synonym)|uniprotkb:MBSP(gene name synonym)|uniprotkb:Serine/threonine protein phosphatase PP1 smooth muscle regulatory subunit M110(gene name synonym)|uniprotkb:Protein phosphatase subunit 1M(gene name synonym) psi-mi:"MI:0424"(protein kinase assay) Takamoto et al. (2006) pubmed:17126281|imex:IM-23035 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0486"(UniProt) intact:EBI-9698982|imex:IM-23035-6 - - psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-77293(isoform-parent)|ensembl:ENSG00000167657(gene)|ensembl:ENST00000301264(transcript)|ensembl:ENST00000545797(transcript) rgd:620013|refseq:NP_446342.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031775|refseq:XP_006241377.1|interpro:IPR017401(Protein phosphatase 1, regulatory subunits 12A/B/C, eukaryote)|interpro:IPR036770|reactome:R-RNO-2565942|reactome:R-RNO-5625740|reactome:R-RNO-5627123|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0019208"(phosphatase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0031672"(A band)|go:"GO:0035507"(regulation of myosin-light-chain-phosphatase activity)|go:"GO:0035508"(positive regulation of myosin-light-chain-phosphatase activity)|go:"GO:0035690"|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043292"(contractile fiber)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0072357"(PTW/PP1 phosphatase complex) go:"GO:0004672"(protein kinase activity)|go:"GO:0006468"(protein phosphorylation) - - figure legend:2D|comment:Phosphorylated and non-phosphorylated DAPK3/ZIPK interacted. Phosphorylation of PPP1R12A/Mypt1 decreases interaction.|antagonist:ATP|resulting-ptm:Q10728 phosphores|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/08/19 2014/10/16 rogid:s8wsdvHltjaM7k0sJRNSjpXVpwM9606 rogid:C2cW3Wgc4JZQGtDsP1NgRkzEr1s10116 intact-crc:21F7CDA70DECF591|rigid:v6dez6kUSZ1MUQjFyX/g2uI7Hsc false - - - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) uniprotkb:O43293-1 - intact:EBI-9691444|ensembl:ENSP00000301264|ensembl:ENSP00000442973 - psi-mi:o43293-1(display_long)|uniprotkb:ZIPK-L(isoform synonym)|uniprotkb:DAPK3(gene name)|psi-mi:DAPK3(display_short)|uniprotkb:ZIPK(gene name synonym)|uniprotkb:DAP-like kinase(gene name synonym)|uniprotkb:MYPT1 kinase(gene name synonym)|uniprotkb:Zipper-interacting protein kinase(gene name synonym) - psi-mi:"MI:0424"(protein kinase assay) Takamoto et al. (2006) pubmed:17126281|imex:IM-23035 taxid:9606(human)|taxid:9606(Homo sapiens) - psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0486"(UniProt) intact:EBI-9699034|imex:IM-23035-8 - - psi-mi:"MI:0499"(unspecified role) - psi-mi:"MI:0898"(putative self) - psi-mi:"MI:0326"(protein) - intact:EBI-77293(isoform-parent)|ensembl:ENSG00000167657(gene)|ensembl:ENST00000301264(transcript)|ensembl:ENST00000545797(transcript) - go:"GO:0004672"(protein kinase activity)|go:"GO:0046777"(protein autophosphorylation) - - figure legend:3A and B. 4A and B|comment:DAPK3/ZIPK mutant ser110ala/thr112ala does not change phosphorylation status.|resulting-ptm:o43293-1 phosphores|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/08/19 2014/10/16 rogid:s8wsdvHltjaM7k0sJRNSjpXVpwM9606 - intact-crc:7736FAF7FF78FDD0 false necessary binding region:278-454 - - - psi-mi:"MI:0833"(autoradiography) - uniprotkb:O43293-2 uniprotkb:O14950 intact:EBI-9691390 intact:EBI-1642165|uniprotkb:D3DUH6|intact:EBI-2826593|uniprotkb:Q7Z5Z4|uniprotkb:Q13182|ensembl:ENSP00000237500|ensembl:ENSP00000383037|ensembl:ENSP00000463559|ensembl:ENSP00000464464|ensembl:ENSP00000496809 psi-mi:o43293-2(display_long)|uniprotkb:ZIPK-S(isoform synonym)|uniprotkb:DAPK3(gene name)|psi-mi:DAPK3(display_short)|uniprotkb:ZIPK(gene name synonym)|uniprotkb:DAP-like kinase(gene name synonym)|uniprotkb:MYPT1 kinase(gene name synonym)|uniprotkb:Zipper-interacting protein kinase(gene name synonym) psi-mi:ml12b_human(display_long)|uniprotkb:MYL12B(gene name)|psi-mi:MYL12B(display_short)|uniprotkb:MRLC2(gene name synonym)|uniprotkb:Myosin regulatory light chain 2-B, smooth muscle isoform(gene name synonym)|uniprotkb:MLC-2A(gene name synonym)|uniprotkb:SHUJUN-1(gene name synonym)|uniprotkb:MYLC2B(gene name synonym)|uniprotkb:Myosin regulatory light chain MRLC2(gene name synonym)|uniprotkb:Myosin regulatory light chain 20 kDa(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Takamoto et al. (2006) pubmed:17126281|imex:IM-23035 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-9691427|imex:IM-23035-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-77293(isoform-parent) refseq:NP_001138416.1|refseq:NP_001138417.1|refseq:NP_291024.1|refseq:NP_001289978.1|ensembl:ENSG00000118680(gene)|ensembl:ENST00000237500(transcript)|ensembl:ENST00000400175(transcript)|ensembl:ENST00000581193(transcript)|ensembl:ENST00000584539(transcript)|ensembl:ENST00000648965(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016460"(myosin II complex)|go:"GO:0030018"(Z disc)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR015070(Region of unknown function DUF1880)|interpro:IPR018247|mint:O14950|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-445355|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123 go:"GO:0001725"(stress fiber) isoform-comment:The internal splice site between exon 8 and the 3' UTR, which yields this truncated isoform, is non-canonical. - figure legend:6Bd|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-arpe_19)|taxid:9606(Homo sapiens retinal pigment epithelial cell line ARPE-19) - 2014/08/19 2014/10/16 rogid:lKWgFqedO62zA+OIlGl4iy8fV309606 rogid:5jOP3J5TW0eU9zwalQ2S4Oist4k9606 intact-crc:BCAF8B9BD3FB26BD|rigid:p+uXIbYC3vLsjsyrYgyEwMn3oOs false myc tag:?-? O-phospho-L-serine:20-20|O-phospho-L-threonine:19-19 - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:O43293-1 uniprotkb:O14950 intact:EBI-9691444|ensembl:ENSP00000301264|ensembl:ENSP00000442973 intact:EBI-1642165|uniprotkb:D3DUH6|intact:EBI-2826593|uniprotkb:Q7Z5Z4|uniprotkb:Q13182|ensembl:ENSP00000237500|ensembl:ENSP00000383037|ensembl:ENSP00000463559|ensembl:ENSP00000464464|ensembl:ENSP00000496809 psi-mi:o43293-1(display_long)|uniprotkb:ZIPK-L(isoform synonym)|uniprotkb:DAPK3(gene name)|psi-mi:DAPK3(display_short)|uniprotkb:ZIPK(gene name synonym)|uniprotkb:DAP-like kinase(gene name synonym)|uniprotkb:MYPT1 kinase(gene name synonym)|uniprotkb:Zipper-interacting protein kinase(gene name synonym) psi-mi:ml12b_human(display_long)|uniprotkb:MYL12B(gene name)|psi-mi:MYL12B(display_short)|uniprotkb:MRLC2(gene name synonym)|uniprotkb:Myosin regulatory light chain 2-B, smooth muscle isoform(gene name synonym)|uniprotkb:MLC-2A(gene name synonym)|uniprotkb:SHUJUN-1(gene name synonym)|uniprotkb:MYLC2B(gene name synonym)|uniprotkb:Myosin regulatory light chain MRLC2(gene name synonym)|uniprotkb:Myosin regulatory light chain 20 kDa(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Takamoto et al. (2006) pubmed:17126281|imex:IM-23035 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-9691437|imex:IM-23035-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-77293(isoform-parent)|ensembl:ENSG00000167657(gene)|ensembl:ENST00000301264(transcript)|ensembl:ENST00000545797(transcript) refseq:NP_001138416.1|refseq:NP_001138417.1|refseq:NP_291024.1|refseq:NP_001289978.1|ensembl:ENSG00000118680(gene)|ensembl:ENST00000237500(transcript)|ensembl:ENST00000400175(transcript)|ensembl:ENST00000581193(transcript)|ensembl:ENST00000584539(transcript)|ensembl:ENST00000648965(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016460"(myosin II complex)|go:"GO:0030018"(Z disc)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR015070(Region of unknown function DUF1880)|interpro:IPR018247|mint:O14950|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-445355|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123 go:"GO:0001725"(stress fiber) - - figure legend:6Ad|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-arpe_19)|taxid:9606(Homo sapiens retinal pigment epithelial cell line ARPE-19) - 2014/08/19 2014/10/16 rogid:s8wsdvHltjaM7k0sJRNSjpXVpwM9606 rogid:5jOP3J5TW0eU9zwalQ2S4Oist4k9606 intact-crc:CC335EA898CBCF07|rigid:7XwP6BPxclzUeEsxIPZ1VA7X2Gw false myc tag:?-? O-phospho-L-serine:20-20|O-phospho-L-threonine:19-19 - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining)