#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9Z254 uniprotkb:Q66T02-2 intact:EBI-991162|uniprotkb:Q6GR70|uniprotkb:Q9QUQ4|ensembl:ENSRNOP00000005374 intact:EBI-9080016|ensembl:ENSMUSP00000081132 psi-mi:gipc1_rat(display_long)|uniprotkb:RGS19-interacting protein 1(gene name synonym)|uniprotkb:GAIP C-terminus-interacting protein(gene name synonym)|uniprotkb:RGS-GAIP-interacting protein(gene name synonym)|uniprotkb:GLUT1 C-terminal-binding protein(gene name synonym)|uniprotkb:Gipc1(gene name)|psi-mi:Gipc1(display_short)|uniprotkb:Gipc(gene name synonym)|uniprotkb:Rgs19ip1(gene name synonym)|uniprotkb:Synectin(gene name synonym) psi-mi:q66t02-2(display_long)|uniprotkb:SYX2(isoform synonym)|uniprotkb:Plekhg5(gene name)|psi-mi:Plekhg5(display_short)|uniprotkb:Kiaa0720(gene name synonym)|uniprotkb:Syx(gene name synonym)|uniprotkb:Synectin-binding RhoA exchange factor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Liu et al. (2006) imex:IM-22031|pubmed:16467373 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9080014 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:68338|refseq:NP_445793.1|ensembl:ENSRNOG00000003864(gene)|ensembl:ENSRNOT00000005374(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006605"(protein targeting)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014047"(glutamate secretion)|go:"GO:0016020"(membrane)|go:"GO:0017022"(myosin binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR017379(Uncharacterised conserved protein UCP038083, PDZ)|interpro:IPR036034|go:"GO:0005903"(brush border)|refseq:XP_017456861.1 intact:EBI-9079953(isoform-parent)|ensembl:ENSMUSG00000039713(gene)|ensembl:ENSMUST00000084115(transcript) intact:EBI-9079994(see-also) - isoform-comment:No experimental confirmation available. figure legend:Fig. 1d|negative:The interaction does not occur under these experimental conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-rfpec)|taxid:10116(Rattus norvegicus epididymal fat pad endothelial cells) - 2014/01/09 2014/10/16 rogid:uqwJJv2JErOO2NJR8CVIxCflozU10116 rogid:v0QB4Xym3Uh361M3Q13OGHMZLpE10090 intact-crc:161E5CBDCEC3B577|rigid:YjljbJrOeXM2Eau8tz5nmwcc9Ss true - green fluorescent protein tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q66T02-2 uniprotkb:P02563 intact:EBI-9080016|ensembl:ENSMUSP00000081132 intact:EBI-6122328|uniprotkb:Q63351 psi-mi:q66t02-2(display_long)|uniprotkb:SYX2(isoform synonym)|uniprotkb:Plekhg5(gene name)|psi-mi:Plekhg5(display_short)|uniprotkb:Kiaa0720(gene name synonym)|uniprotkb:Syx(gene name synonym)|uniprotkb:Synectin-binding RhoA exchange factor(gene name synonym) psi-mi:myh6_rat(display_long)|uniprotkb:Myh6(gene name)|psi-mi:Myh6(display_short)|uniprotkb:Myosin heavy chain 6(gene name synonym)|uniprotkb:Myosin heavy chain, cardiac muscle alpha isoform(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Liu et al. (2006) imex:IM-22031|pubmed:16467373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9080049 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-9079953(isoform-parent)|ensembl:ENSMUSG00000039713(gene)|ensembl:ENSMUST00000084115(transcript) rgd:62029|dip:DIP-41048N|reactome:R-RNO-390522|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007512"(adult heart development)|go:"GO:0007522"(visceral muscle development)|go:"GO:0007568"(aging)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009408"(response to heat)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016459"(myosin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030016"(myofibril)|go:"GO:0030018"(Z disc)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0030239"(myofibril assembly)|go:"GO:0030899"(calcium-dependent ATPase activity)|go:"GO:0032982"(myosin filament)|go:"GO:0042802"(identical protein binding)|go:"GO:0043462"(regulation of ATP-dependent activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051015"(actin filament binding)|go:"GO:0055009"(atrial cardiac muscle tissue morphogenesis)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060420"(regulation of heart growth)|go:"GO:1905243"(cellular response to 3,3',5-triiodo-L-thyronine)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036961 intact:EBI-9080038(see-also) isoform-comment:No experimental confirmation available. - figure legend:Fig. 1d|negative:The interaction does not occur under these experimental conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-rfpec)|taxid:10116(Rattus norvegicus epididymal fat pad endothelial cells) - 2014/01/09 2014/10/16 rogid:v0QB4Xym3Uh361M3Q13OGHMZLpE10090 rogid:nqeGE5gpHiH/OIrWFbbj4AF/AKM10116 intact-crc:7A8213AB782B486D|rigid:mkXneghlSGf7JaZlSQadjP4EQXU true green fluorescent protein tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)