#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P06104 uniprotkb:Q07963 intact:EBI-19722|uniprotkb:D6VU83|ensemblfungi:YGL058W intact:EBI-34338|uniprotkb:D6VY26|ensemblfungi:YLR024C psi-mi:ubc2_yeast(display_long)|uniprotkb:RAD6(gene name)|psi-mi:RAD6(display_short)|uniprotkb:UBC2(gene name synonym)|uniprotkb:Ubiquitin-protein ligase UBC2(gene name synonym)|uniprotkb:Ubiquitin carrier protein UBC2(gene name synonym)|uniprotkb:Radiation sensitivity protein 6(gene name synonym)|uniprotkb:YGL058W(locus name)|uniprotkb:E2 ubiquitin-conjugating enzyme 2(gene name synonym) psi-mi:ubr2_yeast(display_long)|uniprotkb:UBR2(gene name)|psi-mi:UBR2(display_short)|uniprotkb:Ubiquitin-protein ligase E3 component N-recognin-1 homolog(gene name synonym)|uniprotkb:YLR024C(locus name)|uniprotkb:RING-type E3 ubiquitin transferase UBR2(gene name synonym) psi-mi:"MI:0096"(pull down) Wang et al. (2004) pubmed:15504724|imex:IM-22051 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9103652|imex:IM-22051-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011457.1|sgd:S000003026|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033503"(HULC complex)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0042275"(error-free postreplication DNA repair)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070628"(proteasome binding)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:0071596"(ubiquitin-dependent protein catabolic process via the N-end rule pathway)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|go:"GO:0090089"(regulation of dipeptide transport)|go:"GO:0097505"(Rad6-Rad18 complex)|go:"GO:0120174"(stress-induced homeostatically regulated protein degradation pathway)|go:"GO:1990303"(UBR1-RAD6 ubiquitin ligase complex)|go:"GO:1990304"(MUB1-RAD6-UBR2 ubiquitin ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1AYZ|rcsb pdb:4R62|reactome:R-SCE-8866652|reactome:R-SCE-8866654|reactome:R-SCE-983168|ensemblfungi:YGL058W(gene)|ensemblfungi:YGL058W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|dip:DIP-1555N|mint:P06104 refseq:NP_013124.1|sgd:S000004014|mint:Q07963|dip:DIP-6593N|ensemblfungi:YLR024C(gene)|ensemblfungi:YLR024C_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071596"(ubiquitin-dependent protein catabolic process via the N-end rule pathway)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|go:"GO:1990304"(MUB1-RAD6-UBR2 ubiquitin ligase complex)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR039164|interpro:IPR044046|reactome:R-SCE-983168 - crc64:5F568DC28ABBD60F crc64:1F60CC41EB88752F figure legend:Fig 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/01/29 2014/10/16 rogid:NHteg3G6/ga0Apqc/vkqrJJURwg559292 rogid:hKKswIKc5yX/CY6g9RRuGVqlgHQ559292 intact-crc:E4B7F493C4AE5BAA|rigid:5DgWP7J3VbVyDqC7M0PURcM4nLU false glutathione s tranferase tag:?-? flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q07963 uniprotkb:Q03465 intact:EBI-34338|uniprotkb:D6VY26|ensemblfungi:YLR024C intact:EBI-15931|uniprotkb:D6VRX0|uniprotkb:E9P944|ensemblfungi:YDL020C psi-mi:ubr2_yeast(display_long)|uniprotkb:UBR2(gene name)|psi-mi:UBR2(display_short)|uniprotkb:Ubiquitin-protein ligase E3 component N-recognin-1 homolog(gene name synonym)|uniprotkb:YLR024C(locus name)|uniprotkb:RING-type E3 ubiquitin transferase UBR2(gene name synonym) psi-mi:rpn4_yeast(display_long)|uniprotkb:RPN4(gene name)|psi-mi:RPN4(display_short)|uniprotkb:SON1(gene name synonym)|uniprotkb:Nuclear protein SON1(gene name synonym)|uniprotkb:Ubiquitin fusion degradation protein 5(gene name synonym)|uniprotkb:UFD5(gene name synonym)|uniprotkb:D2840(orf name)|uniprotkb:YDL020C(locus name) psi-mi:"MI:0096"(pull down) Wang et al. (2004) pubmed:15504724|imex:IM-22051 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9103663|imex:IM-22051-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013124.1|sgd:S000004014|mint:Q07963|dip:DIP-6593N|ensemblfungi:YLR024C(gene)|ensemblfungi:YLR024C_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071596"(ubiquitin-dependent protein catabolic process via the N-end rule pathway)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|go:"GO:1990304"(MUB1-RAD6-UBR2 ubiquitin ligase complex)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR039164|interpro:IPR044046|reactome:R-SCE-983168 sgd:S000002178|ensemblfungi:YDL020C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061395"(positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0097201"(negative regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|ensemblfungi:YDL020C(gene)|refseq:NP_010264.3|dip:DIP-5779N|mint:Q03465 - crc64:1F60CC41EB88752F - figure legend:Fig 3A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/01/29 2014/10/16 rogid:hKKswIKc5yX/CY6g9RRuGVqlgHQ559292 rogid:pyyaH9X795g/FuGDnW72w8E+5VM559292 intact-crc:42392593379C0257|rigid:ijwWzZ1/49wbad2oiQhcueqm8eQ false flag tag:n-n glutathione s tranferase tag:?-?|sufficient binding region:11-531 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)