#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P38633 uniprotkb:P32569 intact:EBI-17658|uniprotkb:D6VU21|ensemblfungi:YGL127C intact:EBI-18025|uniprotkb:Q06790|uniprotkb:D3DLS1|uniprotkb:Q6B1B4|ensemblfungi:YER022W psi-mi:med31_yeast(display_long)|uniprotkb:SOH1(gene name)|psi-mi:SOH1(display_short)|uniprotkb:YGL127C(locus name)|uniprotkb:G2864(orf name)|uniprotkb:MED31(gene name synonym)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Hpr1 suppressor protein 1(gene name synonym) psi-mi:med17_yeast(display_long)|uniprotkb:YER022W(locus name)|uniprotkb:SRB4(gene name)|psi-mi:SRB4(display_short)|uniprotkb:MED17(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9697156|imex:IM-23040-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL127C(gene)|ensemblfungi:YGL127C_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006311"(meiotic gene conversion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|rcsb pdb:3FBI|rcsb pdb:3FBN|rcsb pdb:5OQM|rcsb pdb:5SVA|refseq:NP_011388.1|sgd:S000003095|dip:DIP-1179N|mint:P38633 refseq:NP_010939.1|sgd:S000000824|ensemblfungi:YER022W(gene)|ensemblfungi:YER022W_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001139"(RNA polymerase II complex recruiting activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR019313|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-152N|mint:P32569 - - crc64:D25B2993A1BADFD6 figure legend:Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2014/10/16 rogid:7jJUtvDYjsYKT1AcECsAgyDmlPw559292 rogid:Wv1UY4bSwZUWPKHLzqiaTRxGbxw559292 intact-crc:25FB60695A74CBAF|rigid:fckmRot3rCgQDKd8bVVZY+imc7c false ha tag:?-? calmodulin binding peptide plus protein a tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P38633 uniprotkb:P32569 intact:EBI-17658|uniprotkb:D6VU21|ensemblfungi:YGL127C intact:EBI-18025|uniprotkb:Q06790|uniprotkb:D3DLS1|uniprotkb:Q6B1B4|ensemblfungi:YER022W psi-mi:med31_yeast(display_long)|uniprotkb:SOH1(gene name)|psi-mi:SOH1(display_short)|uniprotkb:YGL127C(locus name)|uniprotkb:G2864(orf name)|uniprotkb:MED31(gene name synonym)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Hpr1 suppressor protein 1(gene name synonym) psi-mi:med17_yeast(display_long)|uniprotkb:YER022W(locus name)|uniprotkb:SRB4(gene name)|psi-mi:SRB4(display_short)|uniprotkb:MED17(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9697148|imex:IM-23040-22 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL127C(gene)|ensemblfungi:YGL127C_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006311"(meiotic gene conversion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|rcsb pdb:3FBI|rcsb pdb:3FBN|rcsb pdb:5OQM|rcsb pdb:5SVA|refseq:NP_011388.1|sgd:S000003095|dip:DIP-1179N|mint:P38633 refseq:NP_010939.1|sgd:S000000824|ensemblfungi:YER022W(gene)|ensemblfungi:YER022W_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001139"(RNA polymerase II complex recruiting activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR019313|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-152N|mint:P32569 - - crc64:D25B2993A1BADFD6 figure legend:Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2014/10/16 rogid:7jJUtvDYjsYKT1AcECsAgyDmlPw559292 rogid:Wv1UY4bSwZUWPKHLzqiaTRxGbxw559292 intact-crc:344317B504B750F5|rigid:fckmRot3rCgQDKd8bVVZY+imc7c false ha tag:?-? calmodulin binding peptide plus protein a tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P38304 uniprotkb:P32569 intact:EBI-20932|uniprotkb:D6VQI7|ensemblfungi:YBR193C intact:EBI-18025|uniprotkb:Q06790|uniprotkb:D3DLS1|uniprotkb:Q6B1B4|ensemblfungi:YER022W psi-mi:med8_yeast(display_long)|uniprotkb:YBR193C(locus name)|uniprotkb:YBR1403(orf name)|uniprotkb:MED8(gene name)|psi-mi:MED8(display_short)|uniprotkb:Mediator complex subunit 8(gene name synonym) psi-mi:med17_yeast(display_long)|uniprotkb:YER022W(locus name)|uniprotkb:SRB4(gene name)|psi-mi:SRB4(display_short)|uniprotkb:MED17(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 4(gene name synonym) psi-mi:"MI:0018"(two hybrid) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9697007|imex:IM-23040-52 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009752.3|sgd:S000000397|mint:P38304|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|ensemblfungi:YBR193C(gene)|ensemblfungi:YBR193C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|rcsb pdb:2HZS|rcsb pdb:3J1O|dip:DIP-1659N refseq:NP_010939.1|sgd:S000000824|ensemblfungi:YER022W(gene)|ensemblfungi:YER022W_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001139"(RNA polymerase II complex recruiting activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR019313|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-152N|mint:P32569 - crc64:86B2A064293C6B61 crc64:D25B2993A1BADFD6 figure legend:Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2014/10/16 rogid:UdED273ourIyAm1t31wIqC/kKX8559292 rogid:Wv1UY4bSwZUWPKHLzqiaTRxGbxw559292 intact-crc:6EFF1639FFD9783C|rigid:vbmD629D0f7aoE8ROI7DB6O7/ko false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32569 uniprotkb:P32570 intact:EBI-18025|uniprotkb:Q06790|uniprotkb:D3DLS1|uniprotkb:Q6B1B4|ensemblfungi:YER022W intact:EBI-18039|uniprotkb:D6VQP9|ensemblfungi:YBR253W psi-mi:med17_yeast(display_long)|uniprotkb:YER022W(locus name)|uniprotkb:SRB4(gene name)|psi-mi:SRB4(display_short)|uniprotkb:MED17(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 4(gene name synonym) psi-mi:med22_yeast(display_long)|uniprotkb:SRB6(gene name)|psi-mi:SRB6(display_short)|uniprotkb:YBR253W(locus name)|uniprotkb:YBR1721(orf name)|uniprotkb:MED22(gene name synonym)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 6(gene name synonym) psi-mi:"MI:0018"(two hybrid) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9697027|imex:IM-23040-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010939.1|sgd:S000000824|ensemblfungi:YER022W(gene)|ensemblfungi:YER022W_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001139"(RNA polymerase II complex recruiting activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR019313|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-152N|mint:P32569 refseq:NP_009812.1|sgd:S000000457|ensemblfungi:YBR253W(gene)|ensemblfungi:YBR253W_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR009332(Surfeit locus 5)|interpro:IPR016530(Mediator complex, subunit 22)|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-1433N|mint:P32570 - crc64:D25B2993A1BADFD6 crc64:7703E4FAE101A31F figure legend:Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2014/10/16 rogid:Wv1UY4bSwZUWPKHLzqiaTRxGbxw559292 rogid:2MduGxkE+7Ixfj4nr9iaCrCAuYU559292 intact-crc:8962F78767445329|rigid:o7kq0li5NakVHACNL/c4Rvm/9wk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P34162 uniprotkb:P32585 intact:EBI-18018|uniprotkb:D3DKY9|ensemblfungi:YHR041C intact:EBI-18032|uniprotkb:D6VUN6|uniprotkb:Q6B1R3|ensemblfungi:YGR104C psi-mi:med20_yeast(display_long)|uniprotkb:YHR041C(locus name)|uniprotkb:SRB2(gene name)|psi-mi:SRB2(display_short)|uniprotkb:HRS2(gene name synonym)|uniprotkb:MED20(gene name synonym)|uniprotkb:Mediator complex subunit 20(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 2(gene name synonym)|uniprotkb:Hyper-recombination suppressor protein 2(gene name synonym) psi-mi:med18_yeast(display_long)|uniprotkb:YGR104C(locus name)|uniprotkb:SRB5(gene name)|psi-mi:SRB5(display_short)|uniprotkb:MED18(gene name synonym)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 5(gene name synonym) psi-mi:"MI:0018"(two hybrid) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9697031|imex:IM-23040-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011907.1|sgd:S000001083|ensemblfungi:YHR041C(gene)|ensemblfungi:YHR041C_mRNA(transcript)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010689"(negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to chemical stimulus)|go:"GO:0010691"(negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to nutrient levels)|go:"GO:0016592"(mediator complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR013921(TATA-binding related factor)|interpro:IPR016532(Mediator complex, subunit 20)|rcsb pdb:2HZM|rcsb pdb:2HZS|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|dip:DIP-107N|mint:P34162 sgd:S000003336|ensemblfungi:YGR104C(gene)|ensemblfungi:YGR104C_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|rcsb pdb:2HZM|rcsb pdb:2HZS|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|refseq:NP_011618.3|dip:DIP-1658N|mint:P32585 - crc64:C30BF309D43AFB2A crc64:B1148FC187C2802A figure legend:Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2015/07/13 rogid:D2Zs1KYyPj3RbDQC4fz/XtWL+s0559292 rogid:+/qC0affGDlvusbTV43B3aCgZBU559292 intact-crc:A578A58587742F63|rigid:0uCd6brmoLZHw30g/Ez+dm3l3Ro false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38304 uniprotkb:P32585 intact:EBI-20932|uniprotkb:D6VQI7|ensemblfungi:YBR193C intact:EBI-18032|uniprotkb:D6VUN6|uniprotkb:Q6B1R3|ensemblfungi:YGR104C psi-mi:med8_yeast(display_long)|uniprotkb:YBR193C(locus name)|uniprotkb:YBR1403(orf name)|uniprotkb:MED8(gene name)|psi-mi:MED8(display_short)|uniprotkb:Mediator complex subunit 8(gene name synonym) psi-mi:med18_yeast(display_long)|uniprotkb:YGR104C(locus name)|uniprotkb:SRB5(gene name)|psi-mi:SRB5(display_short)|uniprotkb:MED18(gene name synonym)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 5(gene name synonym) psi-mi:"MI:0018"(two hybrid) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9697015|imex:IM-23040-74 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009752.3|sgd:S000000397|mint:P38304|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|ensemblfungi:YBR193C(gene)|ensemblfungi:YBR193C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|rcsb pdb:2HZS|rcsb pdb:3J1O|dip:DIP-1659N sgd:S000003336|ensemblfungi:YGR104C(gene)|ensemblfungi:YGR104C_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|rcsb pdb:2HZM|rcsb pdb:2HZS|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|refseq:NP_011618.3|dip:DIP-1658N|mint:P32585 - crc64:86B2A064293C6B61 crc64:B1148FC187C2802A figure legend:Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2014/10/16 rogid:UdED273ourIyAm1t31wIqC/kKX8559292 rogid:+/qC0affGDlvusbTV43B3aCgZBU559292 intact-crc:765771EFCEEA7E45|rigid:BBeIJ2gPyBe+RSzG+n/+0rB3kr8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99278 uniprotkb:P32569 intact:EBI-27213|uniprotkb:D6VZT5 intact:EBI-18025|uniprotkb:Q06790|uniprotkb:D3DLS1|uniprotkb:Q6B1B4|ensemblfungi:YER022W psi-mi:med11_yeast(display_long)|uniprotkb:YMR112C(locus name)|uniprotkb:YM9718.11C(orf name)|uniprotkb:Mediator complex subunit 11(gene name synonym)|uniprotkb:MED11(gene name)|psi-mi:MED11(display_short) psi-mi:med17_yeast(display_long)|uniprotkb:YER022W(locus name)|uniprotkb:SRB4(gene name)|psi-mi:SRB4(display_short)|uniprotkb:MED17(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 4(gene name synonym) psi-mi:"MI:0018"(two hybrid) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9697011|imex:IM-23040-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004718|refseq:NP_013830.1|mint:Q99278|dip:DIP-1434N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019404|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA refseq:NP_010939.1|sgd:S000000824|ensemblfungi:YER022W(gene)|ensemblfungi:YER022W_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001139"(RNA polymerase II complex recruiting activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR019313|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-152N|mint:P32569 - crc64:457D13C6030F33CC crc64:D25B2993A1BADFD6 figure legend:Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2015/07/13 rogid:rjet29QRORdS5zMRJK/4/KtEF6E559292 rogid:Wv1UY4bSwZUWPKHLzqiaTRxGbxw559292 intact-crc:92D3A2D645ACEA2D|rigid:7INRxs/ATwUozj4a6OXl0MagLHs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99278 uniprotkb:P32570 intact:EBI-27213|uniprotkb:D6VZT5 intact:EBI-18039|uniprotkb:D6VQP9|ensemblfungi:YBR253W psi-mi:med11_yeast(display_long)|uniprotkb:YMR112C(locus name)|uniprotkb:YM9718.11C(orf name)|uniprotkb:Mediator complex subunit 11(gene name synonym)|uniprotkb:MED11(gene name)|psi-mi:MED11(display_short) psi-mi:med22_yeast(display_long)|uniprotkb:SRB6(gene name)|psi-mi:SRB6(display_short)|uniprotkb:YBR253W(locus name)|uniprotkb:YBR1721(orf name)|uniprotkb:MED22(gene name synonym)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 6(gene name synonym) psi-mi:"MI:0018"(two hybrid) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9697023|imex:IM-23040-76 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004718|refseq:NP_013830.1|mint:Q99278|dip:DIP-1434N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019404|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA refseq:NP_009812.1|sgd:S000000457|ensemblfungi:YBR253W(gene)|ensemblfungi:YBR253W_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR009332(Surfeit locus 5)|interpro:IPR016530(Mediator complex, subunit 22)|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-1433N|mint:P32570 - crc64:457D13C6030F33CC crc64:7703E4FAE101A31F figure legend:Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2014/10/16 rogid:rjet29QRORdS5zMRJK/4/KtEF6E559292 rogid:2MduGxkE+7Ixfj4nr9iaCrCAuYU559292 intact-crc:3BC69417A087241B|rigid:N8++ztHiNvLVypOX8iYhK70kFts false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19263 uniprotkb:Q12321 intact:EBI-15087|uniprotkb:Q07999|uniprotkb:D6VY72|ensemblfungi:YLR071C intact:EBI-32854|uniprotkb:D6W474|ensemblfungi:YPR070W psi-mi:med14_yeast(display_long)|uniprotkb:RGR1(gene name)|psi-mi:RGR1(display_short)|uniprotkb:MED14(gene name synonym)|uniprotkb:Mediator complex subunit 14(gene name synonym)|uniprotkb:Glucose repression regulatory protein 1(gene name synonym)|uniprotkb:YLR071C(locus name) psi-mi:med1_yeast(display_long)|uniprotkb:MED1(gene name)|psi-mi:MED1(display_short)|uniprotkb:YPR063W(orf name)|uniprotkb:YPR070W(locus name)|uniprotkb:Mediator complex subunit 1(gene name synonym)|uniprotkb:YP9499.25(orf name) psi-mi:"MI:0018"(two hybrid) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9697051|imex:IM-23040-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013172.1|sgd:S000004061|ensemblfungi:YLR071C(gene)|ensemblfungi:YLR071C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070847"(core mediator complex)|interpro:IPR013947(Mediator complex, subunit MED14)|rcsb pdb:5OQM|dip:DIP-1562N|mint:P19263 refseq:NP_015395.1|sgd:S000006274|mint:Q12321|dip:DIP-1690N|ensemblfungi:YPR070W(gene)|ensemblfungi:YPR070W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR019680 - crc64:96277001829DB539 - figure legend:Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2014/10/16 rogid:WbZxedNQBe+lFVW5hCxmuyAc4r8559292 rogid:vi5smmBUyBLAQ8WbXtFeiAYiA/8559292 intact-crc:4AC2985AD48B3AD1|rigid:vgyVhCJA3CiVu0h13gyelu9OTmM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06213 uniprotkb:Q08278 intact:EBI-12414|ensemblfungi:YPR168W|uniprotkb:D6W4G9 intact:EBI-10674|ensemblfungi:YOL135C|uniprotkb:D6W1T4 psi-mi:med10_yeast(display_long)|uniprotkb:NUT2(gene name)|psi-mi:NUT2(display_short)|uniprotkb:YPR168W(locus name)|uniprotkb:P9325.2(orf name)|uniprotkb:MED10(gene name synonym)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Negative regulator of URS2 protein 2(gene name synonym) psi-mi:med7_yeast(display_long)|uniprotkb:YOL135C(locus name)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short) psi-mi:"MI:0018"(two hybrid) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9697319|imex:IM-23040-60 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPR168W(gene)|ensemblfungi:YPR168W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019145|rcsb pdb:5OQM|refseq:NP_015494.1|sgd:S000006372|mint:Q06213|dip:DIP-3922N refseq:NP_014506.1|sgd:S000005495|ensemblfungi:YOL135C(gene)|ensemblfungi:YOL135C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR009244(MED7)|interpro:IPR037212|rcsb pdb:1YKE|rcsb pdb:1YKH|rcsb pdb:3FBI|rcsb pdb:3FBN|rcsb pdb:5OQM|rcsb pdb:5SVA|mint:Q08278|dip:DIP-1435N - crc64:0E77A43A5222E862 - figure legend:Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2014/10/16 rogid:9sVJRDLvK5nYpDp6u6CJqsAcnhM559292 rogid:26cG32mQDDL8kzdV8k11wI3Yc8w559292 intact-crc:0DF890031618B9EA|rigid:6Odo3LWiLCHmufX24Ov7vt51nqU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08278 uniprotkb:Q06213 intact:EBI-10674|ensemblfungi:YOL135C|uniprotkb:D6W1T4 intact:EBI-12414|ensemblfungi:YPR168W|uniprotkb:D6W4G9 psi-mi:med7_yeast(display_long)|uniprotkb:YOL135C(locus name)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short) psi-mi:med10_yeast(display_long)|uniprotkb:NUT2(gene name)|psi-mi:NUT2(display_short)|uniprotkb:YPR168W(locus name)|uniprotkb:P9325.2(orf name)|uniprotkb:MED10(gene name synonym)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Negative regulator of URS2 protein 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9697075|imex:IM-23040-78 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014506.1|sgd:S000005495|ensemblfungi:YOL135C(gene)|ensemblfungi:YOL135C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR009244(MED7)|interpro:IPR037212|rcsb pdb:1YKE|rcsb pdb:1YKH|rcsb pdb:3FBI|rcsb pdb:3FBN|rcsb pdb:5OQM|rcsb pdb:5SVA|mint:Q08278|dip:DIP-1435N ensemblfungi:YPR168W(gene)|ensemblfungi:YPR168W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019145|rcsb pdb:5OQM|refseq:NP_015494.1|sgd:S000006372|mint:Q06213|dip:DIP-3922N - - crc64:0E77A43A5222E862 figure legend:Fig. 3, Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2014/10/16 rogid:26cG32mQDDL8kzdV8k11wI3Yc8w559292 rogid:9sVJRDLvK5nYpDp6u6CJqsAcnhM559292 intact-crc:B5F751033253B21F|rigid:6Odo3LWiLCHmufX24Ov7vt51nqU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33308 uniprotkb:Q12321 intact:EBI-5174|uniprotkb:D6W1I5|ensemblfungi:YNR010W intact:EBI-32854|uniprotkb:D6W474|ensemblfungi:YPR070W psi-mi:med9_yeast(display_long)|uniprotkb:CSE2(gene name)|psi-mi:CSE2(display_short)|uniprotkb:YNR010W(locus name)|uniprotkb:N2046(orf name)|uniprotkb:MED9(gene name synonym)|uniprotkb:Mediator complex subunit 9(gene name synonym)|uniprotkb:Chromosome segregation protein 2(gene name synonym) psi-mi:med1_yeast(display_long)|uniprotkb:MED1(gene name)|psi-mi:MED1(display_short)|uniprotkb:YPR063W(orf name)|uniprotkb:YPR070W(locus name)|uniprotkb:Mediator complex subunit 1(gene name synonym)|uniprotkb:YP9499.25(orf name) psi-mi:"MI:0018"(two hybrid) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9697047|imex:IM-23040-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005293|refseq:NP_014407.3|dip:DIP-1276N|mint:P33308|ensemblfungi:YNR010W(gene)|ensemblfungi:YNR010W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR011425(RNA polymerase II transcription mediator)|rcsb pdb:5OQM|rcsb pdb:5SVA refseq:NP_015395.1|sgd:S000006274|mint:Q12321|dip:DIP-1690N|ensemblfungi:YPR070W(gene)|ensemblfungi:YPR070W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR019680 - crc64:99D2347F5287AA3C - figure legend:Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2014/10/16 rogid:EHc+XpAIJ3NEiV9uMRTYHy437+U559292 rogid:vi5smmBUyBLAQ8WbXtFeiAYiA/8559292 intact-crc:9A5F85DCBBFECC9D|rigid:a7tlL1mGVotgKB53gGDzhHaCzwQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12343 uniprotkb:P47822 intact:EBI-31503|uniprotkb:D6W2N0|ensemblfungi:YOR174W intact:EBI-18046|uniprotkb:D6VST7|ensemblfungi:YDR308C psi-mi:med4_yeast(display_long)|uniprotkb:O3630(orf name)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:YOR174W(locus name) psi-mi:med21_yeast(display_long)|uniprotkb:SRB7(gene name)|psi-mi:SRB7(display_short)|uniprotkb:YDR308C(locus name)|uniprotkb:D9740.17(orf name)|uniprotkb:MED21(gene name synonym)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNAPII complex component SRB7(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 7(gene name synonym) psi-mi:"MI:0018"(two hybrid) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9697067|imex:IM-23040-56 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005700|refseq:NP_014817.3|dip:DIP-1178N|mint:Q12343|ensemblfungi:YOR174W(gene)|ensemblfungi:YOR174W_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|rcsb pdb:5OQM|rcsb pdb:5SVA sgd:S000002716|ensemblfungi:YDR308C(gene)|ensemblfungi:YDR308C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070847"(core mediator complex)|interpro:IPR021384|interpro:IPR037212|rcsb pdb:1YKE|rcsb pdb:1YKH|rcsb pdb:5OQM|rcsb pdb:5SVA|refseq:NP_010594.3|dip:DIP-290N|mint:P47822 - crc64:D42A3C62D465DDAD crc64:C5B3474AF8DD662A figure legend:Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2014/10/16 rogid:R+wCh3eGS74E+DEQm21XHMd59y0559292 rogid:jlA37XsCdchAsMRiyYLvj20MkiY559292 intact-crc:3D25280FA3465F4B|rigid:s2ua+zMdb+God58r7jifRS6yxK4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38633 uniprotkb:Q06213 intact:EBI-17658|uniprotkb:D6VU21|ensemblfungi:YGL127C intact:EBI-12414|ensemblfungi:YPR168W|uniprotkb:D6W4G9 psi-mi:med31_yeast(display_long)|uniprotkb:SOH1(gene name)|psi-mi:SOH1(display_short)|uniprotkb:YGL127C(locus name)|uniprotkb:G2864(orf name)|uniprotkb:MED31(gene name synonym)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Hpr1 suppressor protein 1(gene name synonym) psi-mi:med10_yeast(display_long)|uniprotkb:NUT2(gene name)|psi-mi:NUT2(display_short)|uniprotkb:YPR168W(locus name)|uniprotkb:P9325.2(orf name)|uniprotkb:MED10(gene name synonym)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Negative regulator of URS2 protein 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9697132|imex:IM-23040-20 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL127C(gene)|ensemblfungi:YGL127C_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006311"(meiotic gene conversion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|rcsb pdb:3FBI|rcsb pdb:3FBN|rcsb pdb:5OQM|rcsb pdb:5SVA|refseq:NP_011388.1|sgd:S000003095|dip:DIP-1179N|mint:P38633 ensemblfungi:YPR168W(gene)|ensemblfungi:YPR168W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019145|rcsb pdb:5OQM|refseq:NP_015494.1|sgd:S000006372|mint:Q06213|dip:DIP-3922N - - crc64:0E77A43A5222E862 figure legend:Fig. 3, Fig 4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2014/10/16 rogid:7jJUtvDYjsYKT1AcECsAgyDmlPw559292 rogid:9sVJRDLvK5nYpDp6u6CJqsAcnhM559292 intact-crc:1ED76643810C9A2A|rigid:wmPuRxIdVJuoxbOi0oajSjsiFCQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38633 uniprotkb:P47822 intact:EBI-17658|uniprotkb:D6VU21|ensemblfungi:YGL127C intact:EBI-18046|uniprotkb:D6VST7|ensemblfungi:YDR308C psi-mi:med31_yeast(display_long)|uniprotkb:SOH1(gene name)|psi-mi:SOH1(display_short)|uniprotkb:YGL127C(locus name)|uniprotkb:G2864(orf name)|uniprotkb:MED31(gene name synonym)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Hpr1 suppressor protein 1(gene name synonym) psi-mi:med21_yeast(display_long)|uniprotkb:SRB7(gene name)|psi-mi:SRB7(display_short)|uniprotkb:YDR308C(locus name)|uniprotkb:D9740.17(orf name)|uniprotkb:MED21(gene name synonym)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNAPII complex component SRB7(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 7(gene name synonym) psi-mi:"MI:0018"(two hybrid) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9697500|imex:IM-23040-43 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL127C(gene)|ensemblfungi:YGL127C_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006311"(meiotic gene conversion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|rcsb pdb:3FBI|rcsb pdb:3FBN|rcsb pdb:5OQM|rcsb pdb:5SVA|refseq:NP_011388.1|sgd:S000003095|dip:DIP-1179N|mint:P38633 sgd:S000002716|ensemblfungi:YDR308C(gene)|ensemblfungi:YDR308C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070847"(core mediator complex)|interpro:IPR021384|interpro:IPR037212|rcsb pdb:1YKE|rcsb pdb:1YKH|rcsb pdb:5OQM|rcsb pdb:5SVA|refseq:NP_010594.3|dip:DIP-290N|mint:P47822 - - crc64:C5B3474AF8DD662A figure legend:Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2014/10/16 rogid:7jJUtvDYjsYKT1AcECsAgyDmlPw559292 rogid:jlA37XsCdchAsMRiyYLvj20MkiY559292 intact-crc:9596BB27DA647D8F|rigid:KrWeR5S9WO7nFvkAui8wzOZD5is false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08278 uniprotkb:Q12343 intact:EBI-10674|ensemblfungi:YOL135C|uniprotkb:D6W1T4 intact:EBI-31503|uniprotkb:D6W2N0|ensemblfungi:YOR174W psi-mi:med7_yeast(display_long)|uniprotkb:YOL135C(locus name)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short) psi-mi:med4_yeast(display_long)|uniprotkb:O3630(orf name)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:YOR174W(locus name) psi-mi:"MI:0018"(two hybrid) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9697189|imex:IM-23040-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014506.1|sgd:S000005495|ensemblfungi:YOL135C(gene)|ensemblfungi:YOL135C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR009244(MED7)|interpro:IPR037212|rcsb pdb:1YKE|rcsb pdb:1YKH|rcsb pdb:3FBI|rcsb pdb:3FBN|rcsb pdb:5OQM|rcsb pdb:5SVA|mint:Q08278|dip:DIP-1435N sgd:S000005700|refseq:NP_014817.3|dip:DIP-1178N|mint:Q12343|ensemblfungi:YOR174W(gene)|ensemblfungi:YOR174W_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|rcsb pdb:5OQM|rcsb pdb:5SVA - - crc64:D42A3C62D465DDAD figure legend:Fig. 3, 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2015/07/13 rogid:26cG32mQDDL8kzdV8k11wI3Yc8w559292 rogid:R+wCh3eGS74E+DEQm21XHMd59y0559292 intact-crc:BA9F6DB6713AD1C5|rigid:h2Wl0IdOte34y4Y0qRMfwpg+FHc false - sufficient binding region:76-260 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12343 uniprotkb:Q06213 intact:EBI-31503|uniprotkb:D6W2N0|ensemblfungi:YOR174W intact:EBI-12414|ensemblfungi:YPR168W|uniprotkb:D6W4G9 psi-mi:med4_yeast(display_long)|uniprotkb:O3630(orf name)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:YOR174W(locus name) psi-mi:med10_yeast(display_long)|uniprotkb:NUT2(gene name)|psi-mi:NUT2(display_short)|uniprotkb:YPR168W(locus name)|uniprotkb:P9325.2(orf name)|uniprotkb:MED10(gene name synonym)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Negative regulator of URS2 protein 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9697195|imex:IM-23040-26 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005700|refseq:NP_014817.3|dip:DIP-1178N|mint:Q12343|ensemblfungi:YOR174W(gene)|ensemblfungi:YOR174W_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|rcsb pdb:5OQM|rcsb pdb:5SVA ensemblfungi:YPR168W(gene)|ensemblfungi:YPR168W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019145|rcsb pdb:5OQM|refseq:NP_015494.1|sgd:S000006372|mint:Q06213|dip:DIP-3922N - crc64:D42A3C62D465DDAD crc64:0E77A43A5222E862 figure legend:Fig. 3, 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2014/10/16 rogid:R+wCh3eGS74E+DEQm21XHMd59y0559292 rogid:9sVJRDLvK5nYpDp6u6CJqsAcnhM559292 intact-crc:6E192A64457A6973|rigid:+/WPKC0k0c3cuNKr1hexB1vXoP8 false sufficient binding region:76-260 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33308 uniprotkb:Q12343 intact:EBI-5174|uniprotkb:D6W1I5|ensemblfungi:YNR010W intact:EBI-31503|uniprotkb:D6W2N0|ensemblfungi:YOR174W psi-mi:med9_yeast(display_long)|uniprotkb:CSE2(gene name)|psi-mi:CSE2(display_short)|uniprotkb:YNR010W(locus name)|uniprotkb:N2046(orf name)|uniprotkb:MED9(gene name synonym)|uniprotkb:Mediator complex subunit 9(gene name synonym)|uniprotkb:Chromosome segregation protein 2(gene name synonym) psi-mi:med4_yeast(display_long)|uniprotkb:O3630(orf name)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:YOR174W(locus name) psi-mi:"MI:0018"(two hybrid) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9697213|imex:IM-23040-29 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005293|refseq:NP_014407.3|dip:DIP-1276N|mint:P33308|ensemblfungi:YNR010W(gene)|ensemblfungi:YNR010W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR011425(RNA polymerase II transcription mediator)|rcsb pdb:5OQM|rcsb pdb:5SVA sgd:S000005700|refseq:NP_014817.3|dip:DIP-1178N|mint:Q12343|ensemblfungi:YOR174W(gene)|ensemblfungi:YOR174W_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|rcsb pdb:5OQM|rcsb pdb:5SVA - crc64:99D2347F5287AA3C crc64:D42A3C62D465DDAD figure legend:Figs. 3, 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2014/10/16 rogid:EHc+XpAIJ3NEiV9uMRTYHy437+U559292 rogid:R+wCh3eGS74E+DEQm21XHMd59y0559292 intact-crc:80429B06AB8AEADB|rigid:5oNKJm/3uuHBA+w7PdoCHf5cB+k false - necessary binding region:1-70 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12321 uniprotkb:Q12343 intact:EBI-32854|uniprotkb:D6W474|ensemblfungi:YPR070W intact:EBI-31503|uniprotkb:D6W2N0|ensemblfungi:YOR174W psi-mi:med1_yeast(display_long)|uniprotkb:MED1(gene name)|psi-mi:MED1(display_short)|uniprotkb:YPR063W(orf name)|uniprotkb:YPR070W(locus name)|uniprotkb:Mediator complex subunit 1(gene name synonym)|uniprotkb:YP9499.25(orf name) psi-mi:med4_yeast(display_long)|uniprotkb:O3630(orf name)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:YOR174W(locus name) psi-mi:"MI:0018"(two hybrid) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9697201|imex:IM-23040-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015395.1|sgd:S000006274|mint:Q12321|dip:DIP-1690N|ensemblfungi:YPR070W(gene)|ensemblfungi:YPR070W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR019680 sgd:S000005700|refseq:NP_014817.3|dip:DIP-1178N|mint:Q12343|ensemblfungi:YOR174W(gene)|ensemblfungi:YOR174W_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|rcsb pdb:5OQM|rcsb pdb:5SVA - - crc64:D42A3C62D465DDAD figure legend:Fig.3, 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2014/10/16 rogid:vi5smmBUyBLAQ8WbXtFeiAYiA/8559292 rogid:R+wCh3eGS74E+DEQm21XHMd59y0559292 intact-crc:61E2C0E52CAC176C|rigid:xX5fwJpuRE0Mto5PELVgCsBbL6Y false - sufficient binding region:76-260 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12343 uniprotkb:P47822 intact:EBI-31503|uniprotkb:D6W2N0|ensemblfungi:YOR174W intact:EBI-18046|uniprotkb:D6VST7|ensemblfungi:YDR308C psi-mi:med4_yeast(display_long)|uniprotkb:O3630(orf name)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:YOR174W(locus name) psi-mi:med21_yeast(display_long)|uniprotkb:SRB7(gene name)|psi-mi:SRB7(display_short)|uniprotkb:YDR308C(locus name)|uniprotkb:D9740.17(orf name)|uniprotkb:MED21(gene name synonym)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNAPII complex component SRB7(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 7(gene name synonym) psi-mi:"MI:0018"(two hybrid) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9697207|imex:IM-23040-28 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005700|refseq:NP_014817.3|dip:DIP-1178N|mint:Q12343|ensemblfungi:YOR174W(gene)|ensemblfungi:YOR174W_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|rcsb pdb:5OQM|rcsb pdb:5SVA sgd:S000002716|ensemblfungi:YDR308C(gene)|ensemblfungi:YDR308C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070847"(core mediator complex)|interpro:IPR021384|interpro:IPR037212|rcsb pdb:1YKE|rcsb pdb:1YKH|rcsb pdb:5OQM|rcsb pdb:5SVA|refseq:NP_010594.3|dip:DIP-290N|mint:P47822 - crc64:D42A3C62D465DDAD crc64:C5B3474AF8DD662A figure legend:Fig. 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2014/10/16 rogid:R+wCh3eGS74E+DEQm21XHMd59y0559292 rogid:jlA37XsCdchAsMRiyYLvj20MkiY559292 intact-crc:E6B57E138166F895|rigid:s2ua+zMdb+God58r7jifRS6yxK4 false sufficient binding region:71-284 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08278 uniprotkb:Q12321 intact:EBI-10674|ensemblfungi:YOL135C|uniprotkb:D6W1T4 intact:EBI-32854|uniprotkb:D6W474|ensemblfungi:YPR070W psi-mi:med7_yeast(display_long)|uniprotkb:YOL135C(locus name)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short) psi-mi:med1_yeast(display_long)|uniprotkb:MED1(gene name)|psi-mi:MED1(display_short)|uniprotkb:YPR063W(orf name)|uniprotkb:YPR070W(locus name)|uniprotkb:Mediator complex subunit 1(gene name synonym)|uniprotkb:YP9499.25(orf name) psi-mi:"MI:0018"(two hybrid) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9697225|imex:IM-23040-31 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014506.1|sgd:S000005495|ensemblfungi:YOL135C(gene)|ensemblfungi:YOL135C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR009244(MED7)|interpro:IPR037212|rcsb pdb:1YKE|rcsb pdb:1YKH|rcsb pdb:3FBI|rcsb pdb:3FBN|rcsb pdb:5OQM|rcsb pdb:5SVA|mint:Q08278|dip:DIP-1435N refseq:NP_015395.1|sgd:S000006274|mint:Q12321|dip:DIP-1690N|ensemblfungi:YPR070W(gene)|ensemblfungi:YPR070W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR019680 - - - figure legend:Fig. 3, 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2014/10/16 rogid:26cG32mQDDL8kzdV8k11wI3Yc8w559292 rogid:vi5smmBUyBLAQ8WbXtFeiAYiA/8559292 intact-crc:D2EB0227AFF7332D|rigid:q4Zq6ykEUP0lw24aVKuAdPR0nhM false sufficient binding region:101-222 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08278 uniprotkb:P33308 intact:EBI-10674|ensemblfungi:YOL135C|uniprotkb:D6W1T4 intact:EBI-5174|uniprotkb:D6W1I5|ensemblfungi:YNR010W psi-mi:med7_yeast(display_long)|uniprotkb:YOL135C(locus name)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short) psi-mi:med9_yeast(display_long)|uniprotkb:CSE2(gene name)|psi-mi:CSE2(display_short)|uniprotkb:YNR010W(locus name)|uniprotkb:N2046(orf name)|uniprotkb:MED9(gene name synonym)|uniprotkb:Mediator complex subunit 9(gene name synonym)|uniprotkb:Chromosome segregation protein 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9697237|imex:IM-23040-33 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014506.1|sgd:S000005495|ensemblfungi:YOL135C(gene)|ensemblfungi:YOL135C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR009244(MED7)|interpro:IPR037212|rcsb pdb:1YKE|rcsb pdb:1YKH|rcsb pdb:3FBI|rcsb pdb:3FBN|rcsb pdb:5OQM|rcsb pdb:5SVA|mint:Q08278|dip:DIP-1435N sgd:S000005293|refseq:NP_014407.3|dip:DIP-1276N|mint:P33308|ensemblfungi:YNR010W(gene)|ensemblfungi:YNR010W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR011425(RNA polymerase II transcription mediator)|rcsb pdb:5OQM|rcsb pdb:5SVA - - crc64:99D2347F5287AA3C figure legend:Fig. 3, 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2014/10/16 rogid:26cG32mQDDL8kzdV8k11wI3Yc8w559292 rogid:EHc+XpAIJ3NEiV9uMRTYHy437+U559292 intact-crc:CB0B359F87779E13|rigid:ekDQHT4NkwJnXIsAcZDbQA0BaCE false necessary binding region:1-100 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08278 uniprotkb:Q06213 intact:EBI-10674|ensemblfungi:YOL135C|uniprotkb:D6W1T4 intact:EBI-12414|ensemblfungi:YPR168W|uniprotkb:D6W4G9 psi-mi:med7_yeast(display_long)|uniprotkb:YOL135C(locus name)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short) psi-mi:med10_yeast(display_long)|uniprotkb:NUT2(gene name)|psi-mi:NUT2(display_short)|uniprotkb:YPR168W(locus name)|uniprotkb:P9325.2(orf name)|uniprotkb:MED10(gene name synonym)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Negative regulator of URS2 protein 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9697219|imex:IM-23040-30 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014506.1|sgd:S000005495|ensemblfungi:YOL135C(gene)|ensemblfungi:YOL135C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR009244(MED7)|interpro:IPR037212|rcsb pdb:1YKE|rcsb pdb:1YKH|rcsb pdb:3FBI|rcsb pdb:3FBN|rcsb pdb:5OQM|rcsb pdb:5SVA|mint:Q08278|dip:DIP-1435N ensemblfungi:YPR168W(gene)|ensemblfungi:YPR168W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019145|rcsb pdb:5OQM|refseq:NP_015494.1|sgd:S000006372|mint:Q06213|dip:DIP-3922N - - crc64:0E77A43A5222E862 figure legend:Fig. 3, 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2014/10/16 rogid:26cG32mQDDL8kzdV8k11wI3Yc8w559292 rogid:9sVJRDLvK5nYpDp6u6CJqsAcnhM559292 intact-crc:183EF97FD01BC5F4|rigid:6Odo3LWiLCHmufX24Ov7vt51nqU false sufficient binding region:101-222 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08278 uniprotkb:P47822 intact:EBI-10674|ensemblfungi:YOL135C|uniprotkb:D6W1T4 intact:EBI-18046|uniprotkb:D6VST7|ensemblfungi:YDR308C psi-mi:med7_yeast(display_long)|uniprotkb:YOL135C(locus name)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short) psi-mi:med21_yeast(display_long)|uniprotkb:SRB7(gene name)|psi-mi:SRB7(display_short)|uniprotkb:YDR308C(locus name)|uniprotkb:D9740.17(orf name)|uniprotkb:MED21(gene name synonym)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNAPII complex component SRB7(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 7(gene name synonym) psi-mi:"MI:0018"(two hybrid) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9697231|imex:IM-23040-32 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014506.1|sgd:S000005495|ensemblfungi:YOL135C(gene)|ensemblfungi:YOL135C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR009244(MED7)|interpro:IPR037212|rcsb pdb:1YKE|rcsb pdb:1YKH|rcsb pdb:3FBI|rcsb pdb:3FBN|rcsb pdb:5OQM|rcsb pdb:5SVA|mint:Q08278|dip:DIP-1435N sgd:S000002716|ensemblfungi:YDR308C(gene)|ensemblfungi:YDR308C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070847"(core mediator complex)|interpro:IPR021384|interpro:IPR037212|rcsb pdb:1YKE|rcsb pdb:1YKH|rcsb pdb:5OQM|rcsb pdb:5SVA|refseq:NP_010594.3|dip:DIP-290N|mint:P47822 - - crc64:C5B3474AF8DD662A figure legend:Fig. 3, 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2014/10/16 rogid:26cG32mQDDL8kzdV8k11wI3Yc8w559292 rogid:jlA37XsCdchAsMRiyYLvj20MkiY559292 intact-crc:DA09D1D3846C01E8|rigid:Q40VWctyi7VZAVqnyGBIrcea/rw false sufficient binding region:101-222 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32569 uniprotkb:P38304 intact:EBI-18025|uniprotkb:Q06790|uniprotkb:D3DLS1|uniprotkb:Q6B1B4|ensemblfungi:YER022W intact:EBI-20932|uniprotkb:D6VQI7|ensemblfungi:YBR193C psi-mi:med17_yeast(display_long)|uniprotkb:YER022W(locus name)|uniprotkb:SRB4(gene name)|psi-mi:SRB4(display_short)|uniprotkb:MED17(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 4(gene name synonym) psi-mi:med8_yeast(display_long)|uniprotkb:YBR193C(locus name)|uniprotkb:YBR1403(orf name)|uniprotkb:MED8(gene name)|psi-mi:MED8(display_short)|uniprotkb:Mediator complex subunit 8(gene name synonym) psi-mi:"MI:0018"(two hybrid) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9697243|imex:IM-23040-34 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010939.1|sgd:S000000824|ensemblfungi:YER022W(gene)|ensemblfungi:YER022W_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001139"(RNA polymerase II complex recruiting activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR019313|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-152N|mint:P32569 refseq:NP_009752.3|sgd:S000000397|mint:P38304|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|ensemblfungi:YBR193C(gene)|ensemblfungi:YBR193C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|rcsb pdb:2HZS|rcsb pdb:3J1O|dip:DIP-1659N - crc64:D25B2993A1BADFD6 crc64:86B2A064293C6B61 figure legend:Fig. 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2014/10/16 rogid:Wv1UY4bSwZUWPKHLzqiaTRxGbxw559292 rogid:UdED273ourIyAm1t31wIqC/kKX8559292 intact-crc:78B8212A94049DFC|rigid:vbmD629D0f7aoE8ROI7DB6O7/ko false - sufficient binding region:182-223 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38304 uniprotkb:P34162 intact:EBI-20932|uniprotkb:D6VQI7|ensemblfungi:YBR193C intact:EBI-18018|uniprotkb:D3DKY9|ensemblfungi:YHR041C psi-mi:med8_yeast(display_long)|uniprotkb:YBR193C(locus name)|uniprotkb:YBR1403(orf name)|uniprotkb:MED8(gene name)|psi-mi:MED8(display_short)|uniprotkb:Mediator complex subunit 8(gene name synonym) psi-mi:med20_yeast(display_long)|uniprotkb:YHR041C(locus name)|uniprotkb:SRB2(gene name)|psi-mi:SRB2(display_short)|uniprotkb:HRS2(gene name synonym)|uniprotkb:MED20(gene name synonym)|uniprotkb:Mediator complex subunit 20(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 2(gene name synonym)|uniprotkb:Hyper-recombination suppressor protein 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9697253|imex:IM-23040-36 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009752.3|sgd:S000000397|mint:P38304|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|ensemblfungi:YBR193C(gene)|ensemblfungi:YBR193C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|rcsb pdb:2HZS|rcsb pdb:3J1O|dip:DIP-1659N refseq:NP_011907.1|sgd:S000001083|ensemblfungi:YHR041C(gene)|ensemblfungi:YHR041C_mRNA(transcript)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010689"(negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to chemical stimulus)|go:"GO:0010691"(negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to nutrient levels)|go:"GO:0016592"(mediator complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR013921(TATA-binding related factor)|interpro:IPR016532(Mediator complex, subunit 20)|rcsb pdb:2HZM|rcsb pdb:2HZS|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|dip:DIP-107N|mint:P34162 - crc64:86B2A064293C6B61 crc64:C30BF309D43AFB2A figure legend:Fig. 3, 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2014/10/16 rogid:UdED273ourIyAm1t31wIqC/kKX8559292 rogid:D2Zs1KYyPj3RbDQC4fz/XtWL+s0559292 intact-crc:5802E47C5389F9E8|rigid:OmtuTj3w/8NpQUyfWdqRPg49reE false necessary binding region:1-181 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32585 uniprotkb:P38304 intact:EBI-18032|uniprotkb:D6VUN6|uniprotkb:Q6B1R3|ensemblfungi:YGR104C intact:EBI-20932|uniprotkb:D6VQI7|ensemblfungi:YBR193C psi-mi:med18_yeast(display_long)|uniprotkb:YGR104C(locus name)|uniprotkb:SRB5(gene name)|psi-mi:SRB5(display_short)|uniprotkb:MED18(gene name synonym)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 5(gene name synonym) psi-mi:med8_yeast(display_long)|uniprotkb:YBR193C(locus name)|uniprotkb:YBR1403(orf name)|uniprotkb:MED8(gene name)|psi-mi:MED8(display_short)|uniprotkb:Mediator complex subunit 8(gene name synonym) psi-mi:"MI:0018"(two hybrid) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9697248|imex:IM-23040-35 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003336|ensemblfungi:YGR104C(gene)|ensemblfungi:YGR104C_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|rcsb pdb:2HZM|rcsb pdb:2HZS|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|refseq:NP_011618.3|dip:DIP-1658N|mint:P32585 refseq:NP_009752.3|sgd:S000000397|mint:P38304|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|ensemblfungi:YBR193C(gene)|ensemblfungi:YBR193C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|rcsb pdb:2HZS|rcsb pdb:3J1O|dip:DIP-1659N - crc64:B1148FC187C2802A crc64:86B2A064293C6B61 figure legend:Fig. 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2014/10/16 rogid:+/qC0affGDlvusbTV43B3aCgZBU559292 rogid:UdED273ourIyAm1t31wIqC/kKX8559292 intact-crc:0F04BD54CE540200|rigid:BBeIJ2gPyBe+RSzG+n/+0rB3kr8 false - sufficient binding region:182-223 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9VS38 uniprotkb:Q9GYU7 intact:EBI-187169|ensemblmetazoa:FBpp0076599 intact:EBI-138576|uniprotkb:Q9VUZ9|ensemblmetazoa:FBpp0290696|ensemblmetazoa:FBpp0305737 psi-mi:med4_drome(display_long)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:CG8609(orf name)|uniprotkb:Trap36(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:dp34(gene name synonym) psi-mi:med10_drome(display_long)|uniprotkb:MED10(gene name)|psi-mi:MED10(display_short)|uniprotkb:Nut2(gene name synonym)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:dMED10(gene name synonym)|uniprotkb:dTRAP15(gene name synonym)|uniprotkb:CG5057(orf name) psi-mi:"MI:0018"(two hybrid) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9697263|imex:IM-23040-38 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_648094.1|flybase:FBgn0035754|dip:DIP-18262N|ensemblmetazoa:FBgn0035754(gene)|ensemblmetazoa:FBtr0076889(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258 go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR019145|ensemblmetazoa:FBgn0036581(gene)|ensemblmetazoa:FBtr0301481(transcript)|ensemblmetazoa:FBtr0333560(transcript)|go:"GO:0000785"(chromatin)|refseq:NP_648849.3|flybase:FBgn0036581|refseq:NP_001261931.1 - - - figure legend:Fig 7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2015/07/13 rogid:7OKu6HUdYgFd1ZmYrbAyA1l0hjc7227 rogid:FMg/VuL23pLH8JVEcRoE6xqL9sg7227 intact-crc:63741FC4C3A39520|rigid:5W6d8VaxB80C6e6inA+pLpCd0e0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9GYU7 uniprotkb:Q9W5P1 intact:EBI-138576|uniprotkb:Q9VUZ9|ensemblmetazoa:FBpp0290696|ensemblmetazoa:FBpp0305737 intact:EBI-500435|uniprotkb:A8Y534|ensemblmetazoa:FBpp0112462|ensemblmetazoa:FBpp0112463 psi-mi:med10_drome(display_long)|uniprotkb:MED10(gene name)|psi-mi:MED10(display_short)|uniprotkb:Nut2(gene name synonym)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:dMED10(gene name synonym)|uniprotkb:dTRAP15(gene name synonym)|uniprotkb:CG5057(orf name) psi-mi:med21_drome(display_long)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:dMED21(gene name synonym)|uniprotkb:dTRAP19(gene name synonym)|uniprotkb:dSRB7(gene name synonym)|uniprotkb:Trap19(gene name synonym)|uniprotkb:CG17397(orf name)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short) psi-mi:"MI:0018"(two hybrid) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9697287|imex:IM-23040-40 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR019145|ensemblmetazoa:FBgn0036581(gene)|ensemblmetazoa:FBtr0301481(transcript)|ensemblmetazoa:FBtr0333560(transcript)|go:"GO:0000785"(chromatin)|refseq:NP_648849.3|flybase:FBgn0036581|refseq:NP_001261931.1 refseq:NP_001015223.1|refseq:NP_001015224.1|flybase:FBgn0040020|ensemblmetazoa:FBgn0040020(gene)|ensemblmetazoa:FBtr0113739(transcript)|ensemblmetazoa:FBtr0113740(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR021384|interpro:IPR037212 - - - figure legend:Fig 7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2014/10/16 rogid:FMg/VuL23pLH8JVEcRoE6xqL9sg7227 rogid:oVptky3FMF+taPTqiiccKUqyFYg7227 intact-crc:3DF72F58A8034C97|rigid:skvcvJqghpBvXr7d6nzXtQs0IfI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9W5P1 uniprotkb:Q9GYV9 intact:EBI-500435|uniprotkb:A8Y534|ensemblmetazoa:FBpp0112462|ensemblmetazoa:FBpp0112463 intact:EBI-9697267|uniprotkb:A0JQ36|ensemblmetazoa:FBpp0081787 psi-mi:med21_drome(display_long)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:dMED21(gene name synonym)|uniprotkb:dTRAP19(gene name synonym)|uniprotkb:dSRB7(gene name synonym)|uniprotkb:Trap19(gene name synonym)|uniprotkb:CG17397(orf name)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short) psi-mi:med7_drome(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:dMED7(gene name synonym)|uniprotkb:CG31390(orf name) psi-mi:"MI:0018"(two hybrid) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9697283|imex:IM-23040-39 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001015223.1|refseq:NP_001015224.1|flybase:FBgn0040020|ensemblmetazoa:FBgn0040020(gene)|ensemblmetazoa:FBtr0113739(transcript)|ensemblmetazoa:FBtr0113740(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR021384|interpro:IPR037212 flybase:FBgn0051390|refseq:NP_731500.1|ensemblmetazoa:FBgn0051390(gene)|ensemblmetazoa:FBtr0082311(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR009244(MED7)|interpro:IPR037212 - - - figure legend:Fig 7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2015/07/13 rogid:oVptky3FMF+taPTqiiccKUqyFYg7227 rogid:xLAGpXbPwpFGQiNX3FD/gD4NyoQ7227 intact-crc:FA0CBAFF5F812D60|rigid:Tu+OkJujBV63nMZyv2jotAOKC7U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32569 uniprotkb:P38633 intact:EBI-18025|uniprotkb:Q06790|uniprotkb:D3DLS1|uniprotkb:Q6B1B4|ensemblfungi:YER022W intact:EBI-17658|uniprotkb:D6VU21|ensemblfungi:YGL127C psi-mi:med17_yeast(display_long)|uniprotkb:YER022W(locus name)|uniprotkb:SRB4(gene name)|psi-mi:SRB4(display_short)|uniprotkb:MED17(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 4(gene name synonym) psi-mi:med31_yeast(display_long)|uniprotkb:SOH1(gene name)|psi-mi:SOH1(display_short)|uniprotkb:YGL127C(locus name)|uniprotkb:G2864(orf name)|uniprotkb:MED31(gene name synonym)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Hpr1 suppressor protein 1(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9697173|imex:IM-23040-24 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010939.1|sgd:S000000824|ensemblfungi:YER022W(gene)|ensemblfungi:YER022W_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001139"(RNA polymerase II complex recruiting activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR019313|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-152N|mint:P32569 ensemblfungi:YGL127C(gene)|ensemblfungi:YGL127C_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006311"(meiotic gene conversion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|rcsb pdb:3FBI|rcsb pdb:3FBN|rcsb pdb:5OQM|rcsb pdb:5SVA|refseq:NP_011388.1|sgd:S000003095|dip:DIP-1179N|mint:P38633 - crc64:D25B2993A1BADFD6 - figure legend:Fig. 4B|comment:Complex was first isolated by anti-HA coimmunoprecipitation.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2014/10/16 rogid:Wv1UY4bSwZUWPKHLzqiaTRxGbxw559292 rogid:7jJUtvDYjsYKT1AcECsAgyDmlPw559292 intact-crc:F4148BBE79A7C85A|rigid:fckmRot3rCgQDKd8bVVZY+imc7c false calmodulin binding peptide plus protein a tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P38633 uniprotkb:P47822 intact:EBI-17658|uniprotkb:D6VU21|ensemblfungi:YGL127C intact:EBI-18046|uniprotkb:D6VST7|ensemblfungi:YDR308C psi-mi:med31_yeast(display_long)|uniprotkb:SOH1(gene name)|psi-mi:SOH1(display_short)|uniprotkb:YGL127C(locus name)|uniprotkb:G2864(orf name)|uniprotkb:MED31(gene name synonym)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Hpr1 suppressor protein 1(gene name synonym) psi-mi:med21_yeast(display_long)|uniprotkb:SRB7(gene name)|psi-mi:SRB7(display_short)|uniprotkb:YDR308C(locus name)|uniprotkb:D9740.17(orf name)|uniprotkb:MED21(gene name synonym)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNAPII complex component SRB7(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 7(gene name synonym) psi-mi:"MI:0018"(two hybrid) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9697019|imex:IM-23040-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL127C(gene)|ensemblfungi:YGL127C_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006311"(meiotic gene conversion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|rcsb pdb:3FBI|rcsb pdb:3FBN|rcsb pdb:5OQM|rcsb pdb:5SVA|refseq:NP_011388.1|sgd:S000003095|dip:DIP-1179N|mint:P38633 sgd:S000002716|ensemblfungi:YDR308C(gene)|ensemblfungi:YDR308C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070847"(core mediator complex)|interpro:IPR021384|interpro:IPR037212|rcsb pdb:1YKE|rcsb pdb:1YKH|rcsb pdb:5OQM|rcsb pdb:5SVA|refseq:NP_010594.3|dip:DIP-290N|mint:P47822 - - crc64:C5B3474AF8DD662A figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2015/07/16 rogid:7jJUtvDYjsYKT1AcECsAgyDmlPw559292 rogid:jlA37XsCdchAsMRiyYLvj20MkiY559292 intact-crc:3B4D1C321E8BE11C|rigid:KrWeR5S9WO7nFvkAui8wzOZD5is false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P47822 uniprotkb:P32569 intact:EBI-18046|uniprotkb:D6VST7|ensemblfungi:YDR308C intact:EBI-18025|uniprotkb:Q06790|uniprotkb:D3DLS1|uniprotkb:Q6B1B4|ensemblfungi:YER022W psi-mi:med21_yeast(display_long)|uniprotkb:SRB7(gene name)|psi-mi:SRB7(display_short)|uniprotkb:YDR308C(locus name)|uniprotkb:D9740.17(orf name)|uniprotkb:MED21(gene name synonym)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNAPII complex component SRB7(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 7(gene name synonym) psi-mi:med17_yeast(display_long)|uniprotkb:YER022W(locus name)|uniprotkb:SRB4(gene name)|psi-mi:SRB4(display_short)|uniprotkb:MED17(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 4(gene name synonym) psi-mi:"MI:0018"(two hybrid) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9697055|imex:IM-23040-54 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002716|ensemblfungi:YDR308C(gene)|ensemblfungi:YDR308C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070847"(core mediator complex)|interpro:IPR021384|interpro:IPR037212|rcsb pdb:1YKE|rcsb pdb:1YKH|rcsb pdb:5OQM|rcsb pdb:5SVA|refseq:NP_010594.3|dip:DIP-290N|mint:P47822 refseq:NP_010939.1|sgd:S000000824|ensemblfungi:YER022W(gene)|ensemblfungi:YER022W_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001139"(RNA polymerase II complex recruiting activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR019313|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-152N|mint:P32569 - crc64:C5B3474AF8DD662A crc64:D25B2993A1BADFD6 figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2015/07/16 rogid:jlA37XsCdchAsMRiyYLvj20MkiY559292 rogid:Wv1UY4bSwZUWPKHLzqiaTRxGbxw559292 intact-crc:9883368A2ADBB44C|rigid:BFq9/ybYWxfBjlaxXAsRuMLbWW0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P40356 uniprotkb:P47822 intact:EBI-13268|uniprotkb:Q6B1W3|uniprotkb:D6VUB3|ensemblfungi:YGL025C intact:EBI-18046|uniprotkb:D6VST7|ensemblfungi:YDR308C psi-mi:med3_yeast(display_long)|uniprotkb:PGD1(gene name)|psi-mi:PGD1(display_short)|uniprotkb:YGL025C(locus name)|uniprotkb:HRS1(gene name synonym)|uniprotkb:MED3(gene name synonym)|uniprotkb:Mediator complex subunit 3(gene name synonym)|uniprotkb:Poly-glutamine domain protein 1(gene name synonym)|uniprotkb:Hyper-recombination suppressor protein 1(gene name synonym) psi-mi:med21_yeast(display_long)|uniprotkb:SRB7(gene name)|psi-mi:SRB7(display_short)|uniprotkb:YDR308C(locus name)|uniprotkb:D9740.17(orf name)|uniprotkb:MED21(gene name synonym)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNAPII complex component SRB7(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 7(gene name synonym) psi-mi:"MI:0018"(two hybrid) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9697079|imex:IM-23040-58 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011490.2|sgd:S000002993|mint:P40356|dip:DIP-1186N|ensemblfungi:YGL025C(gene)|ensemblfungi:YGL025C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070847"(core mediator complex)|interpro:IPR020998 sgd:S000002716|ensemblfungi:YDR308C(gene)|ensemblfungi:YDR308C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070847"(core mediator complex)|interpro:IPR021384|interpro:IPR037212|rcsb pdb:1YKE|rcsb pdb:1YKH|rcsb pdb:5OQM|rcsb pdb:5SVA|refseq:NP_010594.3|dip:DIP-290N|mint:P47822 - - crc64:C5B3474AF8DD662A figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2015/07/16 rogid:oymzNX+JOJG3JMQDdW+3UHzvGzo559292 rogid:jlA37XsCdchAsMRiyYLvj20MkiY559292 intact-crc:A926ADA22394ACD0|rigid:zKP1zrbjgXTd+rEPOhINprXmqMs false sufficient binding region:59-268 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P38931 uniprotkb:P32569 intact:EBI-18059|uniprotkb:D6VT69|ensemblfungi:YDR443C intact:EBI-18025|uniprotkb:Q06790|uniprotkb:D3DLS1|uniprotkb:Q6B1B4|ensemblfungi:YER022W psi-mi:ssn2_yeast(display_long)|uniprotkb:YDR443C(locus name)|uniprotkb:SSN2(gene name)|psi-mi:SSN2(display_short)|uniprotkb:SCA1(gene name synonym)|uniprotkb:MED13(gene name synonym)|uniprotkb:NUT8(gene name synonym)|uniprotkb:RYE3(gene name synonym)|uniprotkb:SRB9(gene name synonym)|uniprotkb:UME2(gene name synonym)|uniprotkb:Mediator complex subunit 13(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B SSN2(gene name synonym)|uniprotkb:Protein SCA1(gene name synonym) psi-mi:med17_yeast(display_long)|uniprotkb:YER022W(locus name)|uniprotkb:SRB4(gene name)|psi-mi:SRB4(display_short)|uniprotkb:MED17(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 4(gene name synonym) psi-mi:"MI:0018"(two hybrid) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9697063|imex:IM-23040-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002851|ensemblfungi:YDR443C(gene)|ensemblfungi:YDR443C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000435"(positive regulation of transcription from RNA polymerase II promoter by galactose)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009401(TRAP240)|interpro:IPR021643|rcsb pdb:7KPV|rcsb pdb:7KPX|refseq:NP_010731.3|dip:DIP-5947N|mint:P38931 refseq:NP_010939.1|sgd:S000000824|ensemblfungi:YER022W(gene)|ensemblfungi:YER022W_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001139"(RNA polymerase II complex recruiting activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR019313|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-152N|mint:P32569 - - crc64:D25B2993A1BADFD6 figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2015/07/16 rogid:eOC/5DvPosnURfkT57c14v4OMdc559292 rogid:Wv1UY4bSwZUWPKHLzqiaTRxGbxw559292 intact-crc:4FC41851ADE77E55|rigid:qs+kbtsXF66E+qjeQyyzFi0G4x0 false sufficient binding region:790-905 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P38782 uniprotkb:P32569 intact:EBI-10667|ensemblfungi:YHR058C|uniprotkb:D3DL07 intact:EBI-18025|uniprotkb:Q06790|uniprotkb:D3DLS1|uniprotkb:Q6B1B4|ensemblfungi:YER022W psi-mi:med6_yeast(display_long)|uniprotkb:MTR32(gene name synonym)|uniprotkb:YHR058C(locus name)|uniprotkb:Mediator complex subunit 6(gene name synonym)|uniprotkb:MED6(gene name)|psi-mi:MED6(display_short) psi-mi:med17_yeast(display_long)|uniprotkb:YER022W(locus name)|uniprotkb:SRB4(gene name)|psi-mi:SRB4(display_short)|uniprotkb:MED17(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 4(gene name synonym) psi-mi:"MI:0018"(two hybrid) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9697043|imex:IM-23040-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011925.1|sgd:S000001100|go:"GO:0070847"(core mediator complex)|interpro:IPR007018(MED6 mediator)|interpro:IPR016612(Mediator complex, subunit 6, fungi)|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|ensemblfungi:YHR058C(gene)|ensemblfungi:YHR058C_mRNA(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|mint:P38782|dip:DIP-2093N refseq:NP_010939.1|sgd:S000000824|ensemblfungi:YER022W(gene)|ensemblfungi:YER022W_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001139"(RNA polymerase II complex recruiting activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR019313|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-152N|mint:P32569 - crc64:B84E87DCC2737849 crc64:D25B2993A1BADFD6 figure legend:Supp. Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2015/07/16 rogid:XcKvvx/GJGRLZpv1MPzpPtVd2RI559292 rogid:Wv1UY4bSwZUWPKHLzqiaTRxGbxw559292 intact-crc:9C846F2E3C09E57E|rigid:w2RVML2Et908BkCHc7jADdL1JGY false sufficient binding region:28-221 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q06213 uniprotkb:P38633 intact:EBI-12414|ensemblfungi:YPR168W|uniprotkb:D6W4G9 intact:EBI-17658|uniprotkb:D6VU21|ensemblfungi:YGL127C psi-mi:med10_yeast(display_long)|uniprotkb:NUT2(gene name)|psi-mi:NUT2(display_short)|uniprotkb:YPR168W(locus name)|uniprotkb:P9325.2(orf name)|uniprotkb:MED10(gene name synonym)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Negative regulator of URS2 protein 2(gene name synonym) psi-mi:med31_yeast(display_long)|uniprotkb:SOH1(gene name)|psi-mi:SOH1(display_short)|uniprotkb:YGL127C(locus name)|uniprotkb:G2864(orf name)|uniprotkb:MED31(gene name synonym)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Hpr1 suppressor protein 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9697035|imex:IM-23040-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPR168W(gene)|ensemblfungi:YPR168W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019145|rcsb pdb:5OQM|refseq:NP_015494.1|sgd:S000006372|mint:Q06213|dip:DIP-3922N ensemblfungi:YGL127C(gene)|ensemblfungi:YGL127C_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006311"(meiotic gene conversion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|rcsb pdb:3FBI|rcsb pdb:3FBN|rcsb pdb:5OQM|rcsb pdb:5SVA|refseq:NP_011388.1|sgd:S000003095|dip:DIP-1179N|mint:P38633 - crc64:0E77A43A5222E862 - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2015/07/16 rogid:9sVJRDLvK5nYpDp6u6CJqsAcnhM559292 rogid:7jJUtvDYjsYKT1AcECsAgyDmlPw559292 intact-crc:1193BD5AD24588C8|rigid:wmPuRxIdVJuoxbOi0oajSjsiFCQ false - sufficient binding region:9-127 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q06213 uniprotkb:P47822 intact:EBI-12414|ensemblfungi:YPR168W|uniprotkb:D6W4G9 intact:EBI-18046|uniprotkb:D6VST7|ensemblfungi:YDR308C psi-mi:med10_yeast(display_long)|uniprotkb:NUT2(gene name)|psi-mi:NUT2(display_short)|uniprotkb:YPR168W(locus name)|uniprotkb:P9325.2(orf name)|uniprotkb:MED10(gene name synonym)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Negative regulator of URS2 protein 2(gene name synonym) psi-mi:med21_yeast(display_long)|uniprotkb:SRB7(gene name)|psi-mi:SRB7(display_short)|uniprotkb:YDR308C(locus name)|uniprotkb:D9740.17(orf name)|uniprotkb:MED21(gene name synonym)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNAPII complex component SRB7(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 7(gene name synonym) psi-mi:"MI:0018"(two hybrid) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9697335|imex:IM-23040-62 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPR168W(gene)|ensemblfungi:YPR168W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019145|rcsb pdb:5OQM|refseq:NP_015494.1|sgd:S000006372|mint:Q06213|dip:DIP-3922N sgd:S000002716|ensemblfungi:YDR308C(gene)|ensemblfungi:YDR308C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070847"(core mediator complex)|interpro:IPR021384|interpro:IPR037212|rcsb pdb:1YKE|rcsb pdb:1YKH|rcsb pdb:5OQM|rcsb pdb:5SVA|refseq:NP_010594.3|dip:DIP-290N|mint:P47822 - crc64:0E77A43A5222E862 crc64:C5B3474AF8DD662A figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2015/07/16 rogid:9sVJRDLvK5nYpDp6u6CJqsAcnhM559292 rogid:jlA37XsCdchAsMRiyYLvj20MkiY559292 intact-crc:6A63F2BE253AFE01|rigid:zlCONNdXxTdf38njjztTOBMOFCo false sufficient binding region:74-157 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P19263 uniprotkb:Q06213 intact:EBI-15087|uniprotkb:Q07999|uniprotkb:D6VY72|ensemblfungi:YLR071C intact:EBI-12414|ensemblfungi:YPR168W|uniprotkb:D6W4G9 psi-mi:med14_yeast(display_long)|uniprotkb:RGR1(gene name)|psi-mi:RGR1(display_short)|uniprotkb:MED14(gene name synonym)|uniprotkb:Mediator complex subunit 14(gene name synonym)|uniprotkb:Glucose repression regulatory protein 1(gene name synonym)|uniprotkb:YLR071C(locus name) psi-mi:med10_yeast(display_long)|uniprotkb:NUT2(gene name)|psi-mi:NUT2(display_short)|uniprotkb:YPR168W(locus name)|uniprotkb:P9325.2(orf name)|uniprotkb:MED10(gene name synonym)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Negative regulator of URS2 protein 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9697071|imex:IM-23040-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013172.1|sgd:S000004061|ensemblfungi:YLR071C(gene)|ensemblfungi:YLR071C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070847"(core mediator complex)|interpro:IPR013947(Mediator complex, subunit MED14)|rcsb pdb:5OQM|dip:DIP-1562N|mint:P19263 ensemblfungi:YPR168W(gene)|ensemblfungi:YPR168W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019145|rcsb pdb:5OQM|refseq:NP_015494.1|sgd:S000006372|mint:Q06213|dip:DIP-3922N - crc64:96277001829DB539 crc64:0E77A43A5222E862 figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2015/07/16 rogid:WbZxedNQBe+lFVW5hCxmuyAc4r8559292 rogid:9sVJRDLvK5nYpDp6u6CJqsAcnhM559292 intact-crc:6476A89477C81C26|rigid:BjOVrcMKHhuhn5T/Hbk3jX3GEKw false sufficient binding region:4-287 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P32259 uniprotkb:P53114 intact:EBI-17172|ensemblfungi:YNL236W|uniprotkb:D6W0V7 intact:EBI-12407|ensemblfungi:YGL151W|uniprotkb:D6VTZ9 psi-mi:med16_yeast(display_long)|uniprotkb:SIN4(gene name)|psi-mi:SIN4(display_short)|uniprotkb:BEL2(gene name synonym)|uniprotkb:GAL22(gene name synonym)|uniprotkb:SSF5(gene name synonym)|uniprotkb:YNL236W(locus name)|uniprotkb:N1135(orf name)|uniprotkb:TSF3(gene name synonym)|uniprotkb:MED16(gene name synonym)|uniprotkb:RYE1(gene name synonym)|uniprotkb:SDI3(gene name synonym)|uniprotkb:SSN4(gene name synonym)|uniprotkb:Mediator complex subunit 16(gene name synonym)|uniprotkb:Global transcriptional regulator SIN4(gene name synonym)|uniprotkb:YGP1 expression regulatory protein 1(gene name synonym)|uniprotkb:Transcriptional silencing factor 3(gene name synonym)|uniprotkb:SWI4 suppressor protein 5(gene name synonym)|uniprotkb:SNF1 suppressor protein 4(gene name synonym) psi-mi:med5_yeast(display_long)|uniprotkb:NUT1(gene name)|psi-mi:NUT1(display_short)|uniprotkb:YGL151W(locus name)|uniprotkb:G1876(orf name)|uniprotkb:MED5(gene name synonym)|uniprotkb:Mediator complex subunit 5(gene name synonym)|uniprotkb:Negative regulator of URS2 protein 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9697059|imex:IM-23040-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014163.1|sgd:S000005180|ensemblfungi:YNL236W(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070202"(regulation of establishment of protein localization to chromosome)|go:"GO:0070847"(core mediator complex)|interpro:IPR021665|ensemblfungi:YNL236W_mRNA(transcript)|dip:DIP-1617N|mint:P32259 ensemblfungi:YGL151W(gene)|ensemblfungi:YGL151W_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0043966"(histone H3 acetylation)|interpro:IPR014801(Mediator complex, subunit Med5)|refseq:NP_011364.1|sgd:S000003119|mint:P53114|dip:DIP-6632N - crc64:12ECF5E4CDC05A8E crc64:BBD54661A4DB5F09 figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2015/07/16 rogid:krTYeU9eXPNnPWcoz+idZe7fRIE559292 rogid:PZX5GBu0/S00vR1eP3R7UYjX6Sk559292 intact-crc:A5A38B2AA839045B|rigid:fabAAbcjXBb53GoqxE9l5q5qPCY false sufficient binding region:1-510 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P38304 uniprotkb:P32585 intact:EBI-20932|uniprotkb:D6VQI7|ensemblfungi:YBR193C intact:EBI-18032|uniprotkb:D6VUN6|uniprotkb:Q6B1R3|ensemblfungi:YGR104C psi-mi:med8_yeast(display_long)|uniprotkb:YBR193C(locus name)|uniprotkb:YBR1403(orf name)|uniprotkb:MED8(gene name)|psi-mi:MED8(display_short)|uniprotkb:Mediator complex subunit 8(gene name synonym) psi-mi:med18_yeast(display_long)|uniprotkb:YGR104C(locus name)|uniprotkb:SRB5(gene name)|psi-mi:SRB5(display_short)|uniprotkb:MED18(gene name synonym)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 5(gene name synonym) psi-mi:"MI:0018"(two hybrid) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-10903170|imex:IM-23040-46 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009752.3|sgd:S000000397|mint:P38304|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|ensemblfungi:YBR193C(gene)|ensemblfungi:YBR193C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|rcsb pdb:2HZS|rcsb pdb:3J1O|dip:DIP-1659N sgd:S000003336|ensemblfungi:YGR104C(gene)|ensemblfungi:YGR104C_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|rcsb pdb:2HZM|rcsb pdb:2HZS|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|refseq:NP_011618.3|dip:DIP-1658N|mint:P32585 - crc64:86B2A064293C6B61 crc64:B1148FC187C2802A figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2015/07/16 rogid:UdED273ourIyAm1t31wIqC/kKX8559292 rogid:+/qC0affGDlvusbTV43B3aCgZBU559292 rigid:BBeIJ2gPyBe+RSzG+n/+0rB3kr8 false sufficient binding region:190-223 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q12343 uniprotkb:Q08278 intact:EBI-31503|uniprotkb:D6W2N0|ensemblfungi:YOR174W intact:EBI-10674|ensemblfungi:YOL135C|uniprotkb:D6W1T4 psi-mi:med4_yeast(display_long)|uniprotkb:O3630(orf name)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:YOR174W(locus name) psi-mi:med7_yeast(display_long)|uniprotkb:YOL135C(locus name)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short) psi-mi:"MI:0018"(two hybrid) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-10903246|imex:IM-23040-68 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005700|refseq:NP_014817.3|dip:DIP-1178N|mint:Q12343|ensemblfungi:YOR174W(gene)|ensemblfungi:YOR174W_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|rcsb pdb:5OQM|rcsb pdb:5SVA refseq:NP_014506.1|sgd:S000005495|ensemblfungi:YOL135C(gene)|ensemblfungi:YOL135C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR009244(MED7)|interpro:IPR037212|rcsb pdb:1YKE|rcsb pdb:1YKH|rcsb pdb:3FBI|rcsb pdb:3FBN|rcsb pdb:5OQM|rcsb pdb:5SVA|mint:Q08278|dip:DIP-1435N - crc64:D42A3C62D465DDAD - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2015/07/16 rogid:R+wCh3eGS74E+DEQm21XHMd59y0559292 rogid:26cG32mQDDL8kzdV8k11wI3Yc8w559292 rigid:h2Wl0IdOte34y4Y0qRMfwpg+FHc false sufficient binding region:76-260 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q08278 uniprotkb:P47822 intact:EBI-10674|ensemblfungi:YOL135C|uniprotkb:D6W1T4 intact:EBI-18046|uniprotkb:D6VST7|ensemblfungi:YDR308C psi-mi:med7_yeast(display_long)|uniprotkb:YOL135C(locus name)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short) psi-mi:med21_yeast(display_long)|uniprotkb:SRB7(gene name)|psi-mi:SRB7(display_short)|uniprotkb:YDR308C(locus name)|uniprotkb:D9740.17(orf name)|uniprotkb:MED21(gene name synonym)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNAPII complex component SRB7(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 7(gene name synonym) psi-mi:"MI:0018"(two hybrid) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-10903163|imex:IM-23040-44 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014506.1|sgd:S000005495|ensemblfungi:YOL135C(gene)|ensemblfungi:YOL135C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR009244(MED7)|interpro:IPR037212|rcsb pdb:1YKE|rcsb pdb:1YKH|rcsb pdb:3FBI|rcsb pdb:3FBN|rcsb pdb:5OQM|rcsb pdb:5SVA|mint:Q08278|dip:DIP-1435N sgd:S000002716|ensemblfungi:YDR308C(gene)|ensemblfungi:YDR308C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070847"(core mediator complex)|interpro:IPR021384|interpro:IPR037212|rcsb pdb:1YKE|rcsb pdb:1YKH|rcsb pdb:5OQM|rcsb pdb:5SVA|refseq:NP_010594.3|dip:DIP-290N|mint:P47822 - - crc64:C5B3474AF8DD662A figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2015/07/16 rogid:26cG32mQDDL8kzdV8k11wI3Yc8w559292 rogid:jlA37XsCdchAsMRiyYLvj20MkiY559292 rigid:Q40VWctyi7VZAVqnyGBIrcea/rw false - sufficient binding region:58-140 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q08278 uniprotkb:P47822 intact:EBI-10674|ensemblfungi:YOL135C|uniprotkb:D6W1T4 intact:EBI-18046|uniprotkb:D6VST7|ensemblfungi:YDR308C psi-mi:med7_yeast(display_long)|uniprotkb:YOL135C(locus name)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short) psi-mi:med21_yeast(display_long)|uniprotkb:SRB7(gene name)|psi-mi:SRB7(display_short)|uniprotkb:YDR308C(locus name)|uniprotkb:D9740.17(orf name)|uniprotkb:MED21(gene name synonym)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNAPII complex component SRB7(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 7(gene name synonym) psi-mi:"MI:0018"(two hybrid) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-10903177|imex:IM-23040-66 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014506.1|sgd:S000005495|ensemblfungi:YOL135C(gene)|ensemblfungi:YOL135C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR009244(MED7)|interpro:IPR037212|rcsb pdb:1YKE|rcsb pdb:1YKH|rcsb pdb:3FBI|rcsb pdb:3FBN|rcsb pdb:5OQM|rcsb pdb:5SVA|mint:Q08278|dip:DIP-1435N sgd:S000002716|ensemblfungi:YDR308C(gene)|ensemblfungi:YDR308C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070847"(core mediator complex)|interpro:IPR021384|interpro:IPR037212|rcsb pdb:1YKE|rcsb pdb:1YKH|rcsb pdb:5OQM|rcsb pdb:5SVA|refseq:NP_010594.3|dip:DIP-290N|mint:P47822 - - crc64:C5B3474AF8DD662A figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2015/07/16 rogid:26cG32mQDDL8kzdV8k11wI3Yc8w559292 rogid:jlA37XsCdchAsMRiyYLvj20MkiY559292 rigid:Q40VWctyi7VZAVqnyGBIrcea/rw false sufficient binding region:131-146 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P53114 uniprotkb:Q12321 intact:EBI-12407|ensemblfungi:YGL151W|uniprotkb:D6VTZ9 intact:EBI-32854|uniprotkb:D6W474|ensemblfungi:YPR070W psi-mi:med5_yeast(display_long)|uniprotkb:NUT1(gene name)|psi-mi:NUT1(display_short)|uniprotkb:YGL151W(locus name)|uniprotkb:G1876(orf name)|uniprotkb:MED5(gene name synonym)|uniprotkb:Mediator complex subunit 5(gene name synonym)|uniprotkb:Negative regulator of URS2 protein 1(gene name synonym) psi-mi:med1_yeast(display_long)|uniprotkb:MED1(gene name)|psi-mi:MED1(display_short)|uniprotkb:YPR063W(orf name)|uniprotkb:YPR070W(locus name)|uniprotkb:Mediator complex subunit 1(gene name synonym)|uniprotkb:YP9499.25(orf name) psi-mi:"MI:0018"(two hybrid) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-10903149|imex:IM-23040-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL151W(gene)|ensemblfungi:YGL151W_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0043966"(histone H3 acetylation)|interpro:IPR014801(Mediator complex, subunit Med5)|refseq:NP_011364.1|sgd:S000003119|mint:P53114|dip:DIP-6632N refseq:NP_015395.1|sgd:S000006274|mint:Q12321|dip:DIP-1690N|ensemblfungi:YPR070W(gene)|ensemblfungi:YPR070W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR019680 - crc64:BBD54661A4DB5F09 - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2015/07/16 rogid:PZX5GBu0/S00vR1eP3R7UYjX6Sk559292 rogid:vi5smmBUyBLAQ8WbXtFeiAYiA/8559292 rigid:Wn1rZ4kll/lKVgC+/UeNUgNb9/8 false - sufficient binding region:137-566 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q08278 uniprotkb:Q06213 intact:EBI-10674|ensemblfungi:YOL135C|uniprotkb:D6W1T4 intact:EBI-12414|ensemblfungi:YPR168W|uniprotkb:D6W4G9 psi-mi:med7_yeast(display_long)|uniprotkb:YOL135C(locus name)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short) psi-mi:med10_yeast(display_long)|uniprotkb:NUT2(gene name)|psi-mi:NUT2(display_short)|uniprotkb:YPR168W(locus name)|uniprotkb:P9325.2(orf name)|uniprotkb:MED10(gene name synonym)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Negative regulator of URS2 protein 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-10903239|imex:IM-23040-48 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014506.1|sgd:S000005495|ensemblfungi:YOL135C(gene)|ensemblfungi:YOL135C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR009244(MED7)|interpro:IPR037212|rcsb pdb:1YKE|rcsb pdb:1YKH|rcsb pdb:3FBI|rcsb pdb:3FBN|rcsb pdb:5OQM|rcsb pdb:5SVA|mint:Q08278|dip:DIP-1435N ensemblfungi:YPR168W(gene)|ensemblfungi:YPR168W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019145|rcsb pdb:5OQM|refseq:NP_015494.1|sgd:S000006372|mint:Q06213|dip:DIP-3922N - - crc64:0E77A43A5222E862 figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2015/07/16 rogid:26cG32mQDDL8kzdV8k11wI3Yc8w559292 rogid:9sVJRDLvK5nYpDp6u6CJqsAcnhM559292 rigid:6Odo3LWiLCHmufX24Ov7vt51nqU false - sufficient binding region:101-157 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q12343 uniprotkb:P47822 intact:EBI-31503|uniprotkb:D6W2N0|ensemblfungi:YOR174W intact:EBI-18046|uniprotkb:D6VST7|ensemblfungi:YDR308C psi-mi:med4_yeast(display_long)|uniprotkb:O3630(orf name)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:YOR174W(locus name) psi-mi:med21_yeast(display_long)|uniprotkb:SRB7(gene name)|psi-mi:SRB7(display_short)|uniprotkb:YDR308C(locus name)|uniprotkb:D9740.17(orf name)|uniprotkb:MED21(gene name synonym)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNAPII complex component SRB7(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 7(gene name synonym) psi-mi:"MI:0018"(two hybrid) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-10903156|imex:IM-23040-64 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005700|refseq:NP_014817.3|dip:DIP-1178N|mint:Q12343|ensemblfungi:YOR174W(gene)|ensemblfungi:YOR174W_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|rcsb pdb:5OQM|rcsb pdb:5SVA sgd:S000002716|ensemblfungi:YDR308C(gene)|ensemblfungi:YDR308C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070847"(core mediator complex)|interpro:IPR021384|interpro:IPR037212|rcsb pdb:1YKE|rcsb pdb:1YKH|rcsb pdb:5OQM|rcsb pdb:5SVA|refseq:NP_010594.3|dip:DIP-290N|mint:P47822 - crc64:D42A3C62D465DDAD crc64:C5B3474AF8DD662A figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2015/07/16 rogid:R+wCh3eGS74E+DEQm21XHMd59y0559292 rogid:jlA37XsCdchAsMRiyYLvj20MkiY559292 rigid:s2ua+zMdb+God58r7jifRS6yxK4 false sufficient binding region:71-235 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99278 uniprotkb:P32570 intact:EBI-27213|uniprotkb:D6VZT5 intact:EBI-18039|uniprotkb:D6VQP9|ensemblfungi:YBR253W psi-mi:med11_yeast(display_long)|uniprotkb:YMR112C(locus name)|uniprotkb:YM9718.11C(orf name)|uniprotkb:Mediator complex subunit 11(gene name synonym)|uniprotkb:MED11(gene name)|psi-mi:MED11(display_short) psi-mi:med22_yeast(display_long)|uniprotkb:SRB6(gene name)|psi-mi:SRB6(display_short)|uniprotkb:YBR253W(locus name)|uniprotkb:YBR1721(orf name)|uniprotkb:MED22(gene name synonym)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 6(gene name synonym) psi-mi:"MI:0018"(two hybrid) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-10903260|imex:IM-23040-72 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004718|refseq:NP_013830.1|mint:Q99278|dip:DIP-1434N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019404|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA refseq:NP_009812.1|sgd:S000000457|ensemblfungi:YBR253W(gene)|ensemblfungi:YBR253W_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR009332(Surfeit locus 5)|interpro:IPR016530(Mediator complex, subunit 22)|rcsb pdb:3J1O|rcsb pdb:3R84|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-1433N|mint:P32570 - crc64:457D13C6030F33CC crc64:7703E4FAE101A31F figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2015/07/16 rogid:rjet29QRORdS5zMRJK/4/KtEF6E559292 rogid:2MduGxkE+7Ixfj4nr9iaCrCAuYU559292 rigid:N8++ztHiNvLVypOX8iYhK70kFts false - sufficient binding region:58-121 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P38304 uniprotkb:P32569 intact:EBI-20932|uniprotkb:D6VQI7|ensemblfungi:YBR193C intact:EBI-18025|uniprotkb:Q06790|uniprotkb:D3DLS1|uniprotkb:Q6B1B4|ensemblfungi:YER022W psi-mi:med8_yeast(display_long)|uniprotkb:YBR193C(locus name)|uniprotkb:YBR1403(orf name)|uniprotkb:MED8(gene name)|psi-mi:MED8(display_short)|uniprotkb:Mediator complex subunit 8(gene name synonym) psi-mi:med17_yeast(display_long)|uniprotkb:YER022W(locus name)|uniprotkb:SRB4(gene name)|psi-mi:SRB4(display_short)|uniprotkb:MED17(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 4(gene name synonym) psi-mi:"MI:0018"(two hybrid) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-10903267|imex:IM-23040-50 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009752.3|sgd:S000000397|mint:P38304|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|ensemblfungi:YBR193C(gene)|ensemblfungi:YBR193C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|rcsb pdb:2HZS|rcsb pdb:3J1O|dip:DIP-1659N refseq:NP_010939.1|sgd:S000000824|ensemblfungi:YER022W(gene)|ensemblfungi:YER022W_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001139"(RNA polymerase II complex recruiting activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR019313|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4H62|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|dip:DIP-152N|mint:P32569 - crc64:86B2A064293C6B61 crc64:D25B2993A1BADFD6 figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2015/07/16 rogid:UdED273ourIyAm1t31wIqC/kKX8559292 rogid:Wv1UY4bSwZUWPKHLzqiaTRxGbxw559292 rigid:vbmD629D0f7aoE8ROI7DB6O7/ko false sufficient binding region:17-218 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q06213 uniprotkb:Q08278 intact:EBI-12414|ensemblfungi:YPR168W|uniprotkb:D6W4G9 intact:EBI-10674|ensemblfungi:YOL135C|uniprotkb:D6W1T4 psi-mi:med10_yeast(display_long)|uniprotkb:NUT2(gene name)|psi-mi:NUT2(display_short)|uniprotkb:YPR168W(locus name)|uniprotkb:P9325.2(orf name)|uniprotkb:MED10(gene name synonym)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Negative regulator of URS2 protein 2(gene name synonym) psi-mi:med7_yeast(display_long)|uniprotkb:YOL135C(locus name)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short) psi-mi:"MI:0018"(two hybrid) Guglielmi et al. (2004) pubmed:15477388|imex:IM-23040 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-10903253|imex:IM-23040-70 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPR168W(gene)|ensemblfungi:YPR168W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019145|rcsb pdb:5OQM|refseq:NP_015494.1|sgd:S000006372|mint:Q06213|dip:DIP-3922N refseq:NP_014506.1|sgd:S000005495|ensemblfungi:YOL135C(gene)|ensemblfungi:YOL135C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR009244(MED7)|interpro:IPR037212|rcsb pdb:1YKE|rcsb pdb:1YKH|rcsb pdb:3FBI|rcsb pdb:3FBN|rcsb pdb:5OQM|rcsb pdb:5SVA|mint:Q08278|dip:DIP-1435N - crc64:0E77A43A5222E862 - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/09/01 2015/07/16 rogid:9sVJRDLvK5nYpDp6u6CJqsAcnhM559292 rogid:26cG32mQDDL8kzdV8k11wI3Yc8w559292 rigid:6Odo3LWiLCHmufX24Ov7vt51nqU false - sufficient binding region:111-203 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)