#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
intact:EBI-9998417	uniprotkb:O92972-PRO_0000278753	-	intact:EBI-10006231	psi-mi:sc1(display_short)|psi-mi:EBI-9998417(display_long)	psi-mi:o92972-pro_0000278753(display_long)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Kim et al. (2004)	pubmed:15364941|imex:IM-26019	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:420174(hcvj4)|taxid:420174("Hepatitis C virus genotype 1b (strain HC-J4) (HCV)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-10026883|imex:IM-26019-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	intact:EBI-710506(chain-parent)	-	-	chain-seq-start:2420|chain-seq-end:3010	figure legend:1B|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/07/16	2017/09/02	rogid:IB2tue88L5Hcyrpd7bKYeB4SGjk-2	rogid:NgYKndLGJidy3gTY6EeBjPXbQSU420174	intact-crc:917A59A6E612E05E|rigid:fjwIXZ8/U7Llq3C28LH+wiva/E0	false	-	his tag:n-n	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:O92972-PRO_0000278753	uniprotkb:Q16513	intact:EBI-10006231	intact:EBI-2511350|uniprotkb:Q9H1W4|uniprotkb:D3DT24|uniprotkb:B4DQ21|uniprotkb:B4DTP5|uniprotkb:B4DVG1|uniprotkb:Q08AF4|ensembl:ENSP00000359552	psi-mi:o92972-pro_0000278753(display_long)	psi-mi:pkn2_human(display_long)|uniprotkb:PKN2(gene name)|psi-mi:PKN2(display_short)|uniprotkb:PRK2(gene name synonym)|uniprotkb:PRKCL2(gene name synonym)|uniprotkb:Protein kinase C-like 2(gene name synonym)|uniprotkb:Protein-kinase C-related kinase 2(gene name synonym)|uniprotkb:PKN gamma(gene name synonym)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Kim et al. (2004)	pubmed:15364941|imex:IM-26019	taxid:420174(hcvj4)|taxid:420174("Hepatitis C virus genotype 1b (strain HC-J4) (HCV)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-9998408|imex:IM-26019-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-710506(chain-parent)	refseq:XP_011540074.1|refseq:NP_006247.1|refseq:NP_001307636.1|refseq:NP_001307637.1|refseq:NP_001307638.1|ensembl:ENSG00000065243(gene)|ensembl:ENST00000370521(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0010631"(epithelial cell migration)|go:"GO:0016301"(kinase activity)|go:"GO:0016604"(nuclear body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0005654"(nucleoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0043297"(apical junction assembly)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051301"(cell division)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000145"(regulation of cell motility)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR035892|interpro:IPR036274|interpro:IPR037313|interpro:IPR037784|mint:Q16513|rcsb pdb:4CRS|rcsb pdb:4RRV|rcsb pdb:6CCY|rcsb pdb:6GBE|reactome:R-HSA-5625740|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013149|go:"GO:0032467"(positive regulation of cytokinesis)	-	chain-seq-start:2420|chain-seq-end:3010	-	figure legend:1B|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/07/16	2014/12/17	rogid:NgYKndLGJidy3gTY6EeBjPXbQSU420174	rogid:KvHDOJ75CgHIGDC+41jGKORm2+w9606	intact-crc:AA99586C9A775B4A|rigid:vB+4UdTCcDK49j+nJrTVcF9kwgo	false	his tag:n-n	mutation:520-520|sufficient binding region:518-525	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:O92972-PRO_0000278753	intact:EBI-9998417	intact:EBI-10006231	-	psi-mi:o92972-pro_0000278753(display_long)	psi-mi:sc1(display_short)|psi-mi:EBI-9998417(display_long)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Kim et al. (2004)	pubmed:15364941|imex:IM-26019	taxid:420174(hcvj4)|taxid:420174("Hepatitis C virus genotype 1b (strain HC-J4) (HCV)")	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-10026878|imex:IM-26019-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0941"(competitor)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0327"(peptide)	intact:EBI-710506(chain-parent)	-	-	chain-seq-start:2420|chain-seq-end:3010	-	figure legend:1B|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/07/16	2014/12/17	rogid:NgYKndLGJidy3gTY6EeBjPXbQSU420174	rogid:IB2tue88L5Hcyrpd7bKYeB4SGjk-2	intact-crc:F2F9DEAD42B3783D|rigid:1iZXsjAEYFqGEcH9rfNSaaIVikg	false	his tag:n-n	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:O92972-PRO_0000278753	uniprotkb:Q16513	intact:EBI-10006231	intact:EBI-2511350|uniprotkb:Q9H1W4|uniprotkb:D3DT24|uniprotkb:B4DQ21|uniprotkb:B4DTP5|uniprotkb:B4DVG1|uniprotkb:Q08AF4|ensembl:ENSP00000359552	psi-mi:o92972-pro_0000278753(display_long)	psi-mi:pkn2_human(display_long)|uniprotkb:PKN2(gene name)|psi-mi:PKN2(display_short)|uniprotkb:PRK2(gene name synonym)|uniprotkb:PRKCL2(gene name synonym)|uniprotkb:Protein kinase C-like 2(gene name synonym)|uniprotkb:Protein-kinase C-related kinase 2(gene name synonym)|uniprotkb:PKN gamma(gene name synonym)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Kim et al. (2004)	pubmed:15364941|imex:IM-26019	taxid:420174(hcvj4)|taxid:420174("Hepatitis C virus genotype 1b (strain HC-J4) (HCV)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-10026878|imex:IM-26019-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-710506(chain-parent)	refseq:XP_011540074.1|refseq:NP_006247.1|refseq:NP_001307636.1|refseq:NP_001307637.1|refseq:NP_001307638.1|ensembl:ENSG00000065243(gene)|ensembl:ENST00000370521(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0010631"(epithelial cell migration)|go:"GO:0016301"(kinase activity)|go:"GO:0016604"(nuclear body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0005654"(nucleoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0043297"(apical junction assembly)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051301"(cell division)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000145"(regulation of cell motility)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR035892|interpro:IPR036274|interpro:IPR037313|interpro:IPR037784|mint:Q16513|rcsb pdb:4CRS|rcsb pdb:4RRV|rcsb pdb:6CCY|rcsb pdb:6GBE|reactome:R-HSA-5625740|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013149|go:"GO:0032467"(positive regulation of cytokinesis)	-	chain-seq-start:2420|chain-seq-end:3010	-	figure legend:1B|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/07/16	2014/12/17	rogid:NgYKndLGJidy3gTY6EeBjPXbQSU420174	rogid:KvHDOJ75CgHIGDC+41jGKORm2+w9606	intact-crc:F2F9DEAD42B3783D|rigid:1iZXsjAEYFqGEcH9rfNSaaIVikg	false	his tag:n-n	mutation:520-520|sufficient binding region:518-525	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:O92972-PRO_0000278753	uniprotkb:Q16513	intact:EBI-10006231	intact:EBI-2511350|uniprotkb:Q9H1W4|uniprotkb:D3DT24|uniprotkb:B4DQ21|uniprotkb:B4DTP5|uniprotkb:B4DVG1|uniprotkb:Q08AF4|ensembl:ENSP00000359552	psi-mi:o92972-pro_0000278753(display_long)	psi-mi:pkn2_human(display_long)|uniprotkb:PKN2(gene name)|psi-mi:PKN2(display_short)|uniprotkb:PRK2(gene name synonym)|uniprotkb:PRKCL2(gene name synonym)|uniprotkb:Protein kinase C-like 2(gene name synonym)|uniprotkb:Protein-kinase C-related kinase 2(gene name synonym)|uniprotkb:PKN gamma(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Kim et al. (2004)	pubmed:15364941|imex:IM-26019	taxid:420174(hcvj4)|taxid:420174("Hepatitis C virus genotype 1b (strain HC-J4) (HCV)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-9678683|imex:IM-26019-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-710506(chain-parent)	refseq:XP_011540074.1|refseq:NP_006247.1|refseq:NP_001307636.1|refseq:NP_001307637.1|refseq:NP_001307638.1|ensembl:ENSG00000065243(gene)|ensembl:ENST00000370521(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0010631"(epithelial cell migration)|go:"GO:0016301"(kinase activity)|go:"GO:0016604"(nuclear body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0005654"(nucleoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0043297"(apical junction assembly)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051301"(cell division)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000145"(regulation of cell motility)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR035892|interpro:IPR036274|interpro:IPR037313|interpro:IPR037784|mint:Q16513|rcsb pdb:4CRS|rcsb pdb:4RRV|rcsb pdb:6CCY|rcsb pdb:6GBE|reactome:R-HSA-5625740|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013149|go:"GO:0032467"(positive regulation of cytokinesis)	-	chain-seq-start:2420|chain-seq-end:3010	-	figure legend:2B-C|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma)	-	2014/07/16	2014/12/09	rogid:NgYKndLGJidy3gTY6EeBjPXbQSU420174	rogid:KvHDOJ75CgHIGDC+41jGKORm2+w9606	intact-crc:CFEAD6BD72CF5DBC|rigid:vB+4UdTCcDK49j+nJrTVcF9kwgo	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q16513	uniprotkb:O92972-PRO_0000278753	intact:EBI-2511350|uniprotkb:Q9H1W4|uniprotkb:D3DT24|uniprotkb:B4DQ21|uniprotkb:B4DTP5|uniprotkb:B4DVG1|uniprotkb:Q08AF4|ensembl:ENSP00000359552	intact:EBI-10006231	psi-mi:pkn2_human(display_long)|uniprotkb:PKN2(gene name)|psi-mi:PKN2(display_short)|uniprotkb:PRK2(gene name synonym)|uniprotkb:PRKCL2(gene name synonym)|uniprotkb:Protein kinase C-like 2(gene name synonym)|uniprotkb:Protein-kinase C-related kinase 2(gene name synonym)|uniprotkb:PKN gamma(gene name synonym)	psi-mi:o92972-pro_0000278753(display_long)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Kim et al. (2004)	pubmed:15364941|imex:IM-26019	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:420174(hcvj4)|taxid:420174("Hepatitis C virus genotype 1b (strain HC-J4) (HCV)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-9678713|imex:IM-26019-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011540074.1|refseq:NP_006247.1|refseq:NP_001307636.1|refseq:NP_001307637.1|refseq:NP_001307638.1|ensembl:ENSG00000065243(gene)|ensembl:ENST00000370521(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0010631"(epithelial cell migration)|go:"GO:0016301"(kinase activity)|go:"GO:0016604"(nuclear body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0005654"(nucleoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0043297"(apical junction assembly)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051301"(cell division)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000145"(regulation of cell motility)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR035892|interpro:IPR036274|interpro:IPR037313|interpro:IPR037784|mint:Q16513|rcsb pdb:4CRS|rcsb pdb:4RRV|rcsb pdb:6CCY|rcsb pdb:6GBE|reactome:R-HSA-5625740|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013149|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0005737"(cytoplasm)	intact:EBI-710506(chain-parent)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)	-	-	chain-seq-start:2420|chain-seq-end:3010	figure legend:4B and 7B|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/07/16	2017/09/02	rogid:KvHDOJ75CgHIGDC+41jGKORm2+w9606	rogid:NgYKndLGJidy3gTY6EeBjPXbQSU420174	intact-crc:DCAB208D23183683|rigid:vB+4UdTCcDK49j+nJrTVcF9kwgo	false	-	necessary binding region:1-187|his tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q16513	uniprotkb:O92972-PRO_0000278753	intact:EBI-2511350|uniprotkb:Q9H1W4|uniprotkb:D3DT24|uniprotkb:B4DQ21|uniprotkb:B4DTP5|uniprotkb:B4DVG1|uniprotkb:Q08AF4|ensembl:ENSP00000359552	intact:EBI-10006231	psi-mi:pkn2_human(display_long)|uniprotkb:PKN2(gene name)|psi-mi:PKN2(display_short)|uniprotkb:PRK2(gene name synonym)|uniprotkb:PRKCL2(gene name synonym)|uniprotkb:Protein kinase C-like 2(gene name synonym)|uniprotkb:Protein-kinase C-related kinase 2(gene name synonym)|uniprotkb:PKN gamma(gene name synonym)	psi-mi:o92972-pro_0000278753(display_long)	psi-mi:"MI:0663"(confocal microscopy)	Kim et al. (2004)	pubmed:15364941|imex:IM-26019	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:420174(hcvj4)|taxid:420174("Hepatitis C virus genotype 1b (strain HC-J4) (HCV)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-9678696|imex:IM-26019-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011540074.1|refseq:NP_006247.1|refseq:NP_001307636.1|refseq:NP_001307637.1|refseq:NP_001307638.1|ensembl:ENSG00000065243(gene)|ensembl:ENST00000370521(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0010631"(epithelial cell migration)|go:"GO:0016301"(kinase activity)|go:"GO:0016604"(nuclear body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0005654"(nucleoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0043297"(apical junction assembly)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051301"(cell division)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000145"(regulation of cell motility)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR035892|interpro:IPR036274|interpro:IPR037313|interpro:IPR037784|mint:Q16513|rcsb pdb:4CRS|rcsb pdb:4RRV|rcsb pdb:6CCY|rcsb pdb:6GBE|reactome:R-HSA-5625740|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013149|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0005737"(cytoplasm)	intact:EBI-710506(chain-parent)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)	go:"GO:0005737"(cytoplasm)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)	-	chain-seq-start:2420|chain-seq-end:3010	figure legend:3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma)	-	2014/07/16	2014/12/09	rogid:KvHDOJ75CgHIGDC+41jGKORm2+w9606	rogid:NgYKndLGJidy3gTY6EeBjPXbQSU420174	intact-crc:F565BB772ABCCEC8|rigid:vB+4UdTCcDK49j+nJrTVcF9kwgo	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q16513	uniprotkb:Q16513	intact:EBI-2511350|uniprotkb:Q9H1W4|uniprotkb:D3DT24|uniprotkb:B4DQ21|uniprotkb:B4DTP5|uniprotkb:B4DVG1|uniprotkb:Q08AF4|ensembl:ENSP00000359552	intact:EBI-2511350|uniprotkb:Q9H1W4|uniprotkb:D3DT24|uniprotkb:B4DQ21|uniprotkb:B4DTP5|uniprotkb:B4DVG1|uniprotkb:Q08AF4|ensembl:ENSP00000359552	psi-mi:pkn2_human(display_long)|uniprotkb:PKN2(gene name)|psi-mi:PKN2(display_short)|uniprotkb:PRK2(gene name synonym)|uniprotkb:PRKCL2(gene name synonym)|uniprotkb:Protein kinase C-like 2(gene name synonym)|uniprotkb:Protein-kinase C-related kinase 2(gene name synonym)|uniprotkb:PKN gamma(gene name synonym)	psi-mi:pkn2_human(display_long)|uniprotkb:PKN2(gene name)|psi-mi:PKN2(display_short)|uniprotkb:PRK2(gene name synonym)|uniprotkb:PRKCL2(gene name synonym)|uniprotkb:Protein kinase C-like 2(gene name synonym)|uniprotkb:Protein-kinase C-related kinase 2(gene name synonym)|uniprotkb:PKN gamma(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Kim et al. (2004)	pubmed:15364941|imex:IM-26019	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-9998439|imex:IM-26019-17	-	-	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011540074.1|refseq:NP_006247.1|refseq:NP_001307636.1|refseq:NP_001307637.1|refseq:NP_001307638.1|ensembl:ENSG00000065243(gene)|ensembl:ENST00000370521(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0010631"(epithelial cell migration)|go:"GO:0016301"(kinase activity)|go:"GO:0016604"(nuclear body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0005654"(nucleoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0043297"(apical junction assembly)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051301"(cell division)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000145"(regulation of cell motility)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR035892|interpro:IPR036274|interpro:IPR037313|interpro:IPR037784|mint:Q16513|rcsb pdb:4CRS|rcsb pdb:4RRV|rcsb pdb:6CCY|rcsb pdb:6GBE|reactome:R-HSA-5625740|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013149|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0005737"(cytoplasm)	refseq:XP_011540074.1|refseq:NP_006247.1|refseq:NP_001307636.1|refseq:NP_001307637.1|refseq:NP_001307638.1|ensembl:ENSG00000065243(gene)|ensembl:ENST00000370521(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0010631"(epithelial cell migration)|go:"GO:0016301"(kinase activity)|go:"GO:0016604"(nuclear body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0005654"(nucleoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0043297"(apical junction assembly)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051301"(cell division)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000145"(regulation of cell motility)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR035892|interpro:IPR036274|interpro:IPR037313|interpro:IPR037784|mint:Q16513|rcsb pdb:4CRS|rcsb pdb:4RRV|rcsb pdb:6CCY|rcsb pdb:6GBE|reactome:R-HSA-5625740|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013149|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0005737"(cytoplasm)	go:"GO:0046777"(protein autophosphorylation)|go:"GO:0004672"(protein kinase activity)	-	-	antagonist:autophosphorylation of immunoprecipitated PRK2 was significantly inhibited by a PRK2-specific inhibitor HA1077.|figure legend:5A, 6B|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/07/16	2017/09/02	rogid:KvHDOJ75CgHIGDC+41jGKORm2+w9606	rogid:KvHDOJ75CgHIGDC+41jGKORm2+w9606	intact-crc:E686BE23ADEA23E9|rigid:IFRWcGWrQMAeFenwmCQIClUgaro	false	-	-	-	0	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q16513	uniprotkb:O92972-PRO_0000278753	intact:EBI-2511350|uniprotkb:Q9H1W4|uniprotkb:D3DT24|uniprotkb:B4DQ21|uniprotkb:B4DTP5|uniprotkb:B4DVG1|uniprotkb:Q08AF4|ensembl:ENSP00000359552	intact:EBI-10006231	psi-mi:pkn2_human(display_long)|uniprotkb:PKN2(gene name)|psi-mi:PKN2(display_short)|uniprotkb:PRK2(gene name synonym)|uniprotkb:PRKCL2(gene name synonym)|uniprotkb:Protein kinase C-like 2(gene name synonym)|uniprotkb:Protein-kinase C-related kinase 2(gene name synonym)|uniprotkb:PKN gamma(gene name synonym)	psi-mi:o92972-pro_0000278753(display_long)	psi-mi:"MI:0424"(protein kinase assay)	Kim et al. (2004)	pubmed:15364941|imex:IM-26019	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:420174(hcvj4)|taxid:420174("Hepatitis C virus genotype 1b (strain HC-J4) (HCV)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-9678732|imex:IM-26019-13	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011540074.1|refseq:NP_006247.1|refseq:NP_001307636.1|refseq:NP_001307637.1|refseq:NP_001307638.1|ensembl:ENSG00000065243(gene)|ensembl:ENST00000370521(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0010631"(epithelial cell migration)|go:"GO:0016301"(kinase activity)|go:"GO:0016604"(nuclear body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0005654"(nucleoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0043297"(apical junction assembly)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051301"(cell division)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000145"(regulation of cell motility)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR035892|interpro:IPR036274|interpro:IPR037313|interpro:IPR037784|mint:Q16513|rcsb pdb:4CRS|rcsb pdb:4RRV|rcsb pdb:6CCY|rcsb pdb:6GBE|reactome:R-HSA-5625740|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013149|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0005737"(cytoplasm)	intact:EBI-710506(chain-parent)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)	go:"GO:0006468"(protein phosphorylation)|go:"GO:0004672"(protein kinase activity)	-	chain-seq-start:2420|chain-seq-end:3010	antagonist:autophosphorylation of immunoprecipitated PRK2 was significantly inhibited by a PRK2-specific inhibitor HA1077 with a concomitant inhibition of NS5B phosphorylation.|figure legend:5A, 6B and 7C|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/07/16	2017/09/02	rogid:KvHDOJ75CgHIGDC+41jGKORm2+w9606	rogid:NgYKndLGJidy3gTY6EeBjPXbQSU420174	intact-crc:1C44B5503FB43435|rigid:vB+4UdTCcDK49j+nJrTVcF9kwgo	false	-	necessary binding region:1-187|his tag:n-n	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q16513	uniprotkb:O92972-PRO_0000278753	intact:EBI-2511350|uniprotkb:Q9H1W4|uniprotkb:D3DT24|uniprotkb:B4DQ21|uniprotkb:B4DTP5|uniprotkb:B4DVG1|uniprotkb:Q08AF4|ensembl:ENSP00000359552	intact:EBI-10006231	psi-mi:pkn2_human(display_long)|uniprotkb:PKN2(gene name)|psi-mi:PKN2(display_short)|uniprotkb:PRK2(gene name synonym)|uniprotkb:PRKCL2(gene name synonym)|uniprotkb:Protein kinase C-like 2(gene name synonym)|uniprotkb:Protein-kinase C-related kinase 2(gene name synonym)|uniprotkb:PKN gamma(gene name synonym)	psi-mi:o92972-pro_0000278753(display_long)	psi-mi:"MI:0084"(phage display)	Kim et al. (2004)	pubmed:15364941|imex:IM-26019	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:420174(hcvj4)|taxid:420174("Hepatitis C virus genotype 1b (strain HC-J4) (HCV)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-9678671|imex:IM-26019-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011540074.1|refseq:NP_006247.1|refseq:NP_001307636.1|refseq:NP_001307637.1|refseq:NP_001307638.1|ensembl:ENSG00000065243(gene)|ensembl:ENST00000370521(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0010631"(epithelial cell migration)|go:"GO:0016301"(kinase activity)|go:"GO:0016604"(nuclear body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0005654"(nucleoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0043297"(apical junction assembly)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051301"(cell division)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000145"(regulation of cell motility)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR035892|interpro:IPR036274|interpro:IPR037313|interpro:IPR037784|mint:Q16513|rcsb pdb:4CRS|rcsb pdb:4RRV|rcsb pdb:6CCY|rcsb pdb:6GBE|reactome:R-HSA-5625740|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013149|go:"GO:0032467"(positive regulation of cytokinesis)	intact:EBI-710506(chain-parent)	-	-	chain-seq-start:2420|chain-seq-end:3010	figure legend:No figure|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/07/16	2014/12/08	rogid:KvHDOJ75CgHIGDC+41jGKORm2+w9606	rogid:NgYKndLGJidy3gTY6EeBjPXbQSU420174	intact-crc:6D71FFA4CABC3310|rigid:vB+4UdTCcDK49j+nJrTVcF9kwgo	false	mutation:520-520|binding-associated region:518-525	his tag:n-n	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)