#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9UNY4 uniprotkb:Q99459 intact:EBI-2322921|uniprotkb:A8K4Q2|uniprotkb:O75921|uniprotkb:Q5T2K7|uniprotkb:Q5VVU8|uniprotkb:Q8N6I8|intact:EBI-28970288|ensembl:ENSP00000358478 intact:EBI-374880|uniprotkb:Q76N46|uniprotkb:Q99974|ensembl:ENSP00000360532 psi-mi:ttf2_human(display_long)|uniprotkb:TTF2(gene name)|psi-mi:TTF2(display_short)|uniprotkb:RNA polymerase II termination factor(gene name synonym)|uniprotkb:Transcription release factor 2(gene name synonym)|uniprotkb:Lodestar homolog(gene name synonym) psi-mi:cdc5l_human(display_long)|uniprotkb:CDC5L(gene name)|psi-mi:CDC5L(display_short)|uniprotkb:Pombe cdc5-related protein(gene name synonym)|uniprotkb:KIAA0432(gene name synonym)|uniprotkb:PCDC5RP(gene name synonym) psi-mi:"MI:0018"(two hybrid) Leonard et al. (2003) pubmed:12927788 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1264"(NTNU) intact:EBI-9276614 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003585.3|ensembl:ENSP00000358478|refseq:XP_016858044.1|ensembl:ENSG00000116830(gene)|ensembl:ENST00000369466(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006397"(mRNA processing)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016787"(hydrolase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR010666(Zinc finger, GRF-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR038718|mint:Q9UNY4 go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|rcsb pdb:6ID1|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071352"(cellular response to interleukin-2)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904568"(cellular response to wortmannin)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990646"(cellular response to prolactin)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR021786|mint:Q99459|rcsb pdb:2DIM|rcsb pdb:2DIN|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|ensembl:ENSG00000096401(gene)|ensembl:ENST00000371477(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7AAV|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|refseq:NP_001244.1|dip:DIP-31731N - - - figure legend:Table.1|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/03/22 2014/10/16 rogid:r4tIdwX2iegp6TXTVoLRPZnhN1A9606 rogid:ZNRraJHn//46wKLSx7xtZju/lr09606 intact-crc:DBA2DEA2F71F11BD|rigid:wRU/kv6/TrFhRiX5NjpenvV/Yy8 false sufficient binding region:1-188 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UNY4 uniprotkb:Q9Y6A5 intact:EBI-2322921|uniprotkb:A8K4Q2|uniprotkb:O75921|uniprotkb:Q5T2K7|uniprotkb:Q5VVU8|uniprotkb:Q8N6I8|intact:EBI-28970288|ensembl:ENSP00000358478 intact:EBI-2554984|uniprotkb:Q2NKK4|uniprotkb:Q9UMQ1|uniprotkb:Q3KQS5|ensembl:ENSP00000326550|ensembl:ENSP00000498361 psi-mi:ttf2_human(display_long)|uniprotkb:TTF2(gene name)|psi-mi:TTF2(display_short)|uniprotkb:RNA polymerase II termination factor(gene name synonym)|uniprotkb:Transcription release factor 2(gene name synonym)|uniprotkb:Lodestar homolog(gene name synonym) psi-mi:tacc3_human(display_long)|uniprotkb:ERIC1(gene name synonym)|uniprotkb:ERIC-1(gene name synonym)|uniprotkb:TACC3(gene name)|psi-mi:TACC3(display_short) psi-mi:"MI:0018"(two hybrid) Leonard et al. (2003) pubmed:12927788 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1264"(NTNU) intact:EBI-9276636 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003585.3|ensembl:ENSP00000358478|refseq:XP_016858044.1|ensembl:ENSG00000116830(gene)|ensembl:ENST00000369466(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006397"(mRNA processing)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016787"(hydrolase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR010666(Zinc finger, GRF-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR038718|mint:Q9UNY4 refseq:NP_006333.1|ensembl:ENSG00000013810(gene)|ensembl:ENST00000313288(transcript)|ensembl:ENST00000651472(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007091"(metaphase/anaphase transition of mitotic cell cycle)|go:"GO:0008283"(cell population proliferation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0034451"(centriolar satellite)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072686"(mitotic spindle)|go:"GO:1902850"(microtubule cytoskeleton organization involved in mitosis)|interpro:IPR007707(Transforming acidic coiled-coil-containing)|interpro:IPR039915|rcsb pdb:5LXN|rcsb pdb:5LXO|rcsb pdb:5ODS|rcsb pdb:5ODT|reactome:R-HSA-9013507|reactome:R-HSA-9604323|refseq:XP_016863142.1 - - - figure legend:Table.1|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/03/22 2015/09/23 rogid:r4tIdwX2iegp6TXTVoLRPZnhN1A9606 rogid:gMVaNgiXeS4kmmJ3ol+/hn9HwXc9606 intact-crc:4FDC0501EBF3DCA2|rigid:meZWSiCg0npzSH01M8ChNiLO54o false sufficient binding region:1-188 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UNY4 uniprotkb:Q9H078 intact:EBI-2322921|uniprotkb:A8K4Q2|uniprotkb:O75921|uniprotkb:Q5T2K7|uniprotkb:Q5VVU8|uniprotkb:Q8N6I8|intact:EBI-28970288|ensembl:ENSP00000358478 intact:EBI-2107221|uniprotkb:Q8ND11|uniprotkb:Q9H8Y0|uniprotkb:B4DXW4|uniprotkb:B4DXJ7|uniprotkb:B4DXP7|uniprotkb:E7EWN6|uniprotkb:F8W7P6|ensembl:ENSP00000294053 psi-mi:ttf2_human(display_long)|uniprotkb:TTF2(gene name)|psi-mi:TTF2(display_short)|uniprotkb:RNA polymerase II termination factor(gene name synonym)|uniprotkb:Transcription release factor 2(gene name synonym)|uniprotkb:Lodestar homolog(gene name synonym) psi-mi:clpb_human(display_long)|uniprotkb:CLPB(gene name)|psi-mi:CLPB(display_short)|uniprotkb:HSP78(gene name synonym)|uniprotkb:SKD3(gene name synonym)|uniprotkb:Suppressor of potassium transport defect 3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Leonard et al. (2003) pubmed:12927788 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1264"(NTNU) intact:EBI-9276639 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003585.3|ensembl:ENSP00000358478|refseq:XP_016858044.1|ensembl:ENSG00000116830(gene)|ensembl:ENST00000369466(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006397"(mRNA processing)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016787"(hydrolase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR010666(Zinc finger, GRF-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR038718|mint:Q9UNY4 refseq:NP_110440.1|refseq:NP_001245321.1|refseq:NP_001245322.1|refseq:NP_001245323.1|ensembl:ENSG00000162129(gene)|ensembl:ENST00000294053(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0034605"(cellular response to heat)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR002110(Ankyrin)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR019489|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|mint:Q9H078 - - - figure legend:Table.1|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/03/22 2015/09/23 rogid:r4tIdwX2iegp6TXTVoLRPZnhN1A9606 rogid:QqIOYOITwDC+c8kKtMGBHa/0Tjk9606 intact-crc:AEF89E89B5D52322|rigid:yIFVH6MGNk0ODixlWB4qwCm0FIs false sufficient binding region:1-188 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UNY4 uniprotkb:Q15025 intact:EBI-2322921|uniprotkb:A8K4Q2|uniprotkb:O75921|uniprotkb:Q5T2K7|uniprotkb:Q5VVU8|uniprotkb:Q8N6I8|intact:EBI-28970288|ensembl:ENSP00000358478 intact:EBI-357849|uniprotkb:A4F1W8|uniprotkb:O76008|uniprotkb:Q96EL9|uniprotkb:Q99833|uniprotkb:Q9H1J3|uniprotkb:B7Z699|uniprotkb:Q6N077|ensembl:ENSP00000317891|ensembl:ENSP00000428187|ensembl:ENSP00000430760|uniprotkb:A4F1W9|uniprotkb:A4F1X2|uniprotkb:A4F1X4|uniprotkb:A4F1X5|uniprotkb:A4F1X6|uniprotkb:A4F1X7|uniprotkb:A4F1X9|uniprotkb:E7EPY1|uniprotkb:E7ET96|uniprotkb:Q05KP3|uniprotkb:Q05KP4 psi-mi:ttf2_human(display_long)|uniprotkb:TTF2(gene name)|psi-mi:TTF2(display_short)|uniprotkb:RNA polymerase II termination factor(gene name synonym)|uniprotkb:Transcription release factor 2(gene name synonym)|uniprotkb:Lodestar homolog(gene name synonym) psi-mi:tnip1_human(display_long)|uniprotkb:TNIP1(gene name)|psi-mi:TNIP1(display_short)|uniprotkb:KIAA0113(gene name synonym)|uniprotkb:NAF1(gene name synonym)|uniprotkb:Nef-associated factor 1(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)|uniprotkb:Virion-associated nuclear shuttling protein(gene name synonym)|uniprotkb:Nip40-1(gene name synonym)|uniprotkb:A20-binding inhibitor of NF-kappa-B activation 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Leonard et al. (2003) pubmed:12927788 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1264"(NTNU) intact:EBI-9276642 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003585.3|ensembl:ENSP00000358478|refseq:XP_016858044.1|ensembl:ENSG00000116830(gene)|ensembl:ENST00000369466(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006397"(mRNA processing)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016787"(hydrolase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR010666(Zinc finger, GRF-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR038718|mint:Q9UNY4 refseq:NP_006049.3|refseq:NP_001239319.1|refseq:NP_001239320.1|refseq:NP_001239321.1|refseq:NP_001239322.1|refseq:NP_001245383.1|dip:DIP-27577N|refseq:NP_001239315.1|ensembl:ENSG00000145901(gene)|ensembl:ENST00000315050(transcript)|ensembl:ENST00000521591(transcript)|ensembl:ENST00000522226(transcript)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0009101"(glycoprotein biosynthetic process)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0085032"(modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade)|go:"GO:1903003"(positive regulation of protein deubiquitination)|interpro:IPR033372|mint:Q15025|reactome:R-HSA-5689896|go:"GO:0051019"(mitogen-activated protein kinase binding)|refseq:NP_001239314.1|refseq:NP_001245384.1|refseq:NP_001245385.1|refseq:XP_006714814.1|refseq:XP_006714815.1 - - - figure legend:Table.1|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/03/22 2015/09/23 rogid:r4tIdwX2iegp6TXTVoLRPZnhN1A9606 rogid:16Vjb5CuGTAbW2M22qbCxgXtV1o9606 intact-crc:35E9A1D014E42007|rigid:mzjdxPu/KiBwck1ybzkCVtkWYaE false sufficient binding region:1-188 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UNY4 uniprotkb:P10244 intact:EBI-2322921|uniprotkb:A8K4Q2|uniprotkb:O75921|uniprotkb:Q5T2K7|uniprotkb:Q5VVU8|uniprotkb:Q8N6I8|intact:EBI-28970288|ensembl:ENSP00000358478 intact:EBI-1389468|uniprotkb:B2RBS5|uniprotkb:B7Z8D9|uniprotkb:F8W6N6|uniprotkb:Q53F07|ensembl:ENSP00000217026 psi-mi:ttf2_human(display_long)|uniprotkb:TTF2(gene name)|psi-mi:TTF2(display_short)|uniprotkb:RNA polymerase II termination factor(gene name synonym)|uniprotkb:Transcription release factor 2(gene name synonym)|uniprotkb:Lodestar homolog(gene name synonym) psi-mi:mybb_human(display_long)|uniprotkb:Myb-like protein 2(gene name synonym)|uniprotkb:MYBL2(gene name)|psi-mi:MYBL2(display_short)|uniprotkb:BMYB(gene name synonym) psi-mi:"MI:0018"(two hybrid) Leonard et al. (2003) pubmed:12927788 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1264"(NTNU) intact:EBI-9276645 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003585.3|ensembl:ENSP00000358478|refseq:XP_016858044.1|ensembl:ENSG00000116830(gene)|ensembl:ENST00000369466(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006397"(mRNA processing)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016787"(hydrolase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR010666(Zinc finger, GRF-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR038718|mint:Q9UNY4 refseq:NP_001265539.1|refseq:NP_002457.1|ensembl:ENSG00000101057(gene)|ensembl:ENST00000217026(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0031523"(Myb complex)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR015395(C-myb, C-terminal)|interpro:IPR017930|interpro:IPR028311|mint:P10244|rcsb pdb:6C48|reactome:R-HSA-1362300|reactome:R-HSA-156711|reactome:R-HSA-8869496 - - - figure legend:Table.1|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/03/22 2015/09/23 rogid:r4tIdwX2iegp6TXTVoLRPZnhN1A9606 rogid:2ldntN2B+u1fHcK4WPkL9UZYbzs9606 intact-crc:64D5E29BFBA20D6C|rigid:a+EJWpZ6+f09sDtQuoo4eWb+xyk false sufficient binding region:1-188 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UNY4 uniprotkb:Q14919 intact:EBI-2322921|uniprotkb:A8K4Q2|uniprotkb:O75921|uniprotkb:Q5T2K7|uniprotkb:Q5VVU8|uniprotkb:Q8N6I8|intact:EBI-28970288|ensembl:ENSP00000358478 intact:EBI-712941|uniprotkb:Q13448|ensembl:ENSP00000307850 psi-mi:ttf2_human(display_long)|uniprotkb:TTF2(gene name)|psi-mi:TTF2(display_short)|uniprotkb:RNA polymerase II termination factor(gene name synonym)|uniprotkb:Transcription release factor 2(gene name synonym)|uniprotkb:Lodestar homolog(gene name synonym) psi-mi:nc2a_human(display_long)|uniprotkb:Dr1-associated protein 1(gene name synonym)|uniprotkb:DRAP1(gene name)|psi-mi:DRAP1(display_short)|uniprotkb:Negative cofactor 2-alpha(gene name synonym) psi-mi:"MI:0018"(two hybrid) Leonard et al. (2003) pubmed:12927788 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1264"(NTNU) intact:EBI-9276648 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003585.3|ensembl:ENSP00000358478|refseq:XP_016858044.1|ensembl:ENSG00000116830(gene)|ensembl:ENST00000369466(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006397"(mRNA processing)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016787"(hydrolase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR010666(Zinc finger, GRF-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR038718|mint:Q9UNY4 refseq:NP_006433.2|reactome:R-HSA-1181150|reactome:R-HSA-1502540|rcsb pdb:1JFI|ensembl:ENSG00000175550(gene)|ensembl:ENST00000312515(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001091"(RNA polymerase II general transcription initiation factor binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0017054"(negative cofactor 2 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003958(Transcription factor CBF/NF-Y/archaeal histone)|interpro:IPR009072(Histone-fold)|mint:Q14919 - - - figure legend:Table.1|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/03/22 2015/09/23 rogid:r4tIdwX2iegp6TXTVoLRPZnhN1A9606 rogid:ek/+ddQxp2b8JYDGwwBwTX5VYfg9606 intact-crc:E84F31B984168D57|rigid:HnNIlApE6aJoEk4qo8mrvZFCf/g false sufficient binding region:1-188 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UNY4 uniprotkb:Q9NPI6 intact:EBI-2322921|uniprotkb:A8K4Q2|uniprotkb:O75921|uniprotkb:Q5T2K7|uniprotkb:Q5VVU8|uniprotkb:Q8N6I8|intact:EBI-28970288|ensembl:ENSP00000358478 intact:EBI-374238|ensembl:ENSP00000476386|uniprotkb:B4DHN9|uniprotkb:U3KQM8 psi-mi:ttf2_human(display_long)|uniprotkb:TTF2(gene name)|psi-mi:TTF2(display_short)|uniprotkb:RNA polymerase II termination factor(gene name synonym)|uniprotkb:Transcription release factor 2(gene name synonym)|uniprotkb:Lodestar homolog(gene name synonym) psi-mi:dcp1a_human(display_long)|uniprotkb:DCP1A(gene name)|psi-mi:DCP1A(display_short)|uniprotkb:Transcription factor SMIF(gene name synonym)|uniprotkb:Smad4-interacting transcriptional co-activator(gene name synonym)|uniprotkb:SMIF(gene name synonym) psi-mi:"MI:0018"(two hybrid) Leonard et al. (2003) pubmed:12927788 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1264"(NTNU) intact:EBI-9276651 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003585.3|ensembl:ENSP00000358478|refseq:XP_016858044.1|ensembl:ENSG00000116830(gene)|ensembl:ENST00000369466(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006397"(mRNA processing)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016787"(hydrolase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR010666(Zinc finger, GRF-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR038718|mint:Q9UNY4 ensembl:ENSG00000272886(gene)|ensembl:ENST00000610213(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019894"(kinesin binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q9NPI6|rcsb pdb:2WX3|rcsb pdb:4B6H|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-975957|refseq:NP_060873.4|refseq:NP_001277133.1|refseq:NP_001277136.1|refseq:NP_001277134.1|refseq:NP_001277135.1|dip:DIP-31292N - - - figure legend:Table.1|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/03/22 2018/09/18 rogid:r4tIdwX2iegp6TXTVoLRPZnhN1A9606 rogid:KIg2pPmAEIiig2SXAJNziN91oCY9606 intact-crc:4055753CCC29B716|rigid:Z7qbkozdL+W3/t4EL2pb5ZI06EM false sufficient binding region:1-188 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UNY4 uniprotkb:Q13162 intact:EBI-2322921|uniprotkb:A8K4Q2|uniprotkb:O75921|uniprotkb:Q5T2K7|uniprotkb:Q5VVU8|uniprotkb:Q8N6I8|intact:EBI-28970288|ensembl:ENSP00000358478 intact:EBI-2211957|uniprotkb:Q6FHT3|ensembl:ENSP00000368646 psi-mi:ttf2_human(display_long)|uniprotkb:TTF2(gene name)|psi-mi:TTF2(display_short)|uniprotkb:RNA polymerase II termination factor(gene name synonym)|uniprotkb:Transcription release factor 2(gene name synonym)|uniprotkb:Lodestar homolog(gene name synonym) psi-mi:prdx4_human(display_long)|uniprotkb:PRDX4(gene name)|psi-mi:PRDX4(display_short)|uniprotkb:Peroxiredoxin IV(gene name synonym)|uniprotkb:Thioredoxin peroxidase AO372(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase A0372(gene name synonym)|uniprotkb:Antioxidant enzyme AOE372(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 4(gene name synonym) psi-mi:"MI:0018"(two hybrid) Leonard et al. (2003) pubmed:12927788 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1264"(NTNU) intact:EBI-9276654 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003585.3|ensembl:ENSP00000358478|refseq:XP_016858044.1|ensembl:ENSG00000116830(gene)|ensembl:ENST00000369466(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006397"(mRNA processing)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016787"(hydrolase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR010666(Zinc finger, GRF-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR038718|mint:Q9UNY4 refseq:NP_006397.1|ensembl:ENSG00000123131(gene)|ensembl:ENST00000379341(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007252"(I-kappaB phosphorylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0008584"(male gonad development)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2000255"(negative regulation of male germ cell proliferation)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR036249|mint:Q13162|rcsb pdb:2PN8|rcsb pdb:3TJB|rcsb pdb:3TJF|rcsb pdb:3TJG|rcsb pdb:3TJJ|rcsb pdb:3TJK|rcsb pdb:3TKP|rcsb pdb:3TKQ|rcsb pdb:3TKR|rcsb pdb:3TKS|rcsb pdb:4RQX|rcsb pdb:5HQP|reactome:R-HSA-6798695 - - - figure legend:Table.1|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/03/22 2015/09/23 rogid:r4tIdwX2iegp6TXTVoLRPZnhN1A9606 rogid:5KWl3YuUpRDrSUxWlJS6sP7CLAs9606 intact-crc:37A5668F5B5CCE24|rigid:RZ0LI0+DX3xshP1qb6ecirow8G0 false sufficient binding region:1-188 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UNY4 uniprotkb:Q8WUM4 intact:EBI-2322921|uniprotkb:A8K4Q2|uniprotkb:O75921|uniprotkb:Q5T2K7|uniprotkb:Q5VVU8|uniprotkb:Q8N6I8|intact:EBI-28970288|ensembl:ENSP00000358478 intact:EBI-310624|uniprotkb:Q9BX86|uniprotkb:Q9NUN0|uniprotkb:Q9P2H2|uniprotkb:Q9UKL5|uniprotkb:C5MQH7|intact:EBI-10971645|uniprotkb:E9PFU1|uniprotkb:Q6NUS1|ensembl:ENSP00000307387|intact:EBI-28983290 psi-mi:ttf2_human(display_long)|uniprotkb:TTF2(gene name)|psi-mi:TTF2(display_short)|uniprotkb:RNA polymerase II termination factor(gene name synonym)|uniprotkb:Transcription release factor 2(gene name synonym)|uniprotkb:Lodestar homolog(gene name synonym) psi-mi:pdc6i_human(display_long)|uniprotkb:PDCD6IP(gene name)|psi-mi:PDCD6IP(display_short)|uniprotkb:AIP1(gene name synonym)|uniprotkb:KIAA1375(gene name synonym)|uniprotkb:ALIX(gene name synonym)|uniprotkb:ALG-2-interacting protein 1(gene name synonym)|uniprotkb:Hp95(gene name synonym)|uniprotkb:ALG-2-interacting protein X(gene name synonym) psi-mi:"MI:0018"(two hybrid) Leonard et al. (2003) pubmed:12927788 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1264"(NTNU) intact:EBI-9276658 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003585.3|ensembl:ENSP00000358478|refseq:XP_016858044.1|ensembl:ENSG00000116830(gene)|ensembl:ENST00000369466(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006397"(mRNA processing)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016787"(hydrolase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR010666(Zinc finger, GRF-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR038718|mint:Q9UNY4 refseq:NP_037506.2|ensembl:ENSP00000307387|ensembl:ENST00000457054|ensembl:ENSP00000411825|refseq:NP_001155901.1|ensembl:ENSG00000170248(gene)|ensembl:ENST00000307296(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0001772"(immunological synapse)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006915"(apoptotic process)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0031871"(proteinase activated receptor binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042470"(melanosome)|go:"GO:0042641"(actomyosin)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0046755"(viral budding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090543"(Flemming body)|go:"GO:0090559"(regulation of membrane permeability)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903553"(positive regulation of extracellular exosome assembly)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR004328(BRO1)|interpro:IPR025304|interpro:IPR038499|mint:Q8WUM4|rcsb pdb:2OEV|rcsb pdb:2OEW|rcsb pdb:2OEX|rcsb pdb:2OJQ|rcsb pdb:2R02|rcsb pdb:2R03|rcsb pdb:2R05|rcsb pdb:2XS1|rcsb pdb:2XS8|rcsb pdb:2ZNE|rcsb pdb:3C3O|rcsb pdb:3C3Q|rcsb pdb:3C3R|rcsb pdb:3E1R|rcsb pdb:3WUV|rcsb pdb:4JJY|rcsb pdb:5V3R|rcsb pdb:5WA1|rcsb pdb:6KP3|reactome:R-HSA-162588|reactome:R-HSA-5210891|reactome:R-HSA-5213460|reactome:R-HSA-5675482|refseq:NP_001243121.1|dip:DIP-29327N - - - figure legend:Table.1|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/03/22 2015/09/23 rogid:r4tIdwX2iegp6TXTVoLRPZnhN1A9606 rogid:FYD19EyMBAGl204Xlgr4MlE8GMs9606 intact-crc:2606E40E3AB008F2|rigid:zEq2xN2If5/X93h6pWVJq4wGLiA false sufficient binding region:1-188 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UNY4 uniprotkb:O15381 intact:EBI-2322921|uniprotkb:A8K4Q2|uniprotkb:O75921|uniprotkb:Q5T2K7|uniprotkb:Q5VVU8|uniprotkb:Q8N6I8|intact:EBI-28970288|ensembl:ENSP00000358478 intact:EBI-721638|uniprotkb:Q96EM7|uniprotkb:B4DMC4|uniprotkb:B4DP98|ensembl:ENSP00000281701 psi-mi:ttf2_human(display_long)|uniprotkb:TTF2(gene name)|psi-mi:TTF2(display_short)|uniprotkb:RNA polymerase II termination factor(gene name synonym)|uniprotkb:Transcription release factor 2(gene name synonym)|uniprotkb:Lodestar homolog(gene name synonym) psi-mi:nvl_human(display_long)|uniprotkb:NVL(gene name)|psi-mi:NVL(display_short)|uniprotkb:NVL2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Leonard et al. (2003) pubmed:12927788 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1264"(NTNU) intact:EBI-9276662 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003585.3|ensembl:ENSP00000358478|refseq:XP_016858044.1|ensembl:ENSG00000116830(gene)|ensembl:ENST00000369466(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006397"(mRNA processing)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016787"(hydrolase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR010666(Zinc finger, GRF-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR038718|mint:Q9UNY4 refseq:NP_002524.2|refseq:NP_996671.1|refseq:NP_001230075.1|refseq:NP_001230076.1|ensembl:ENSG00000143748(gene)|ensembl:ENST00000281701(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:1904749"(regulation of protein localization to nucleolus)|go:"GO:1990275"(preribosome binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR031996|interpro:IPR038100|interpro:IPR041569|mint:O15381|rcsb pdb:2X8A|rcsb pdb:6RO1 - - - figure legend:Table.1|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/03/22 2015/09/23 rogid:r4tIdwX2iegp6TXTVoLRPZnhN1A9606 rogid:3xAHor7LoQCGSzrRQWhKaEuqd9A9606 intact-crc:1FBDA28C779F1344|rigid:kV26lhZt+8y3Hti79r9oBvCpvMw false sufficient binding region:1-188 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UNY4 uniprotkb:Q99459 intact:EBI-2322921|uniprotkb:A8K4Q2|uniprotkb:O75921|uniprotkb:Q5T2K7|uniprotkb:Q5VVU8|uniprotkb:Q8N6I8|intact:EBI-28970288|ensembl:ENSP00000358478 intact:EBI-374880|uniprotkb:Q76N46|uniprotkb:Q99974|ensembl:ENSP00000360532 psi-mi:ttf2_human(display_long)|uniprotkb:TTF2(gene name)|psi-mi:TTF2(display_short)|uniprotkb:RNA polymerase II termination factor(gene name synonym)|uniprotkb:Transcription release factor 2(gene name synonym)|uniprotkb:Lodestar homolog(gene name synonym) psi-mi:cdc5l_human(display_long)|uniprotkb:CDC5L(gene name)|psi-mi:CDC5L(display_short)|uniprotkb:Pombe cdc5-related protein(gene name synonym)|uniprotkb:KIAA0432(gene name synonym)|uniprotkb:PCDC5RP(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Leonard et al. (2003) pubmed:12927788 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1264"(NTNU) intact:EBI-9276665 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003585.3|ensembl:ENSP00000358478|refseq:XP_016858044.1|ensembl:ENSG00000116830(gene)|ensembl:ENST00000369466(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006397"(mRNA processing)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016787"(hydrolase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR010666(Zinc finger, GRF-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR038718|mint:Q9UNY4 go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|rcsb pdb:6ID1|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071352"(cellular response to interleukin-2)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904568"(cellular response to wortmannin)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990646"(cellular response to prolactin)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR021786|mint:Q99459|rcsb pdb:2DIM|rcsb pdb:2DIN|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|ensembl:ENSG00000096401(gene)|ensembl:ENST00000371477(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7AAV|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|refseq:NP_001244.1|dip:DIP-31731N - - - figure legend:Fig. 2A|curation depth:imex curation taxid:9606(human-ht1080)|taxid:9606(Homo sapiens HT1080 fribrosarcoma cell line) - 2014/03/22 2015/09/23 rogid:r4tIdwX2iegp6TXTVoLRPZnhN1A9606 rogid:ZNRraJHn//46wKLSx7xtZju/lr09606 intact-crc:DE36E49DCFFED9EB|rigid:exzAdJhvy+Vdf1s2jll5b3zXous false 35s radiolabel:?-? 35s radiolabel:?-? - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9UNY4 uniprotkb:P09651 intact:EBI-2322921|uniprotkb:A8K4Q2|uniprotkb:O75921|uniprotkb:Q5T2K7|uniprotkb:Q5VVU8|uniprotkb:Q8N6I8|intact:EBI-28970288|ensembl:ENSP00000358478 intact:EBI-352662|uniprotkb:Q3MIB7|uniprotkb:Q6PJZ7|ensembl:ENSP00000341826|ensembl:ENSP00000503610|uniprotkb:A8K4Z8|intact:EBI-2556572 psi-mi:ttf2_human(display_long)|uniprotkb:TTF2(gene name)|psi-mi:TTF2(display_short)|uniprotkb:RNA polymerase II termination factor(gene name synonym)|uniprotkb:Transcription release factor 2(gene name synonym)|uniprotkb:Lodestar homolog(gene name synonym) psi-mi:roa1_human(display_long)|uniprotkb:HNRNPA1(gene name)|psi-mi:HNRNPA1(display_short)|uniprotkb:HNRPA1(gene name synonym)|uniprotkb:Helix-destabilizing protein(gene name synonym)|uniprotkb:Single-strand RNA-binding protein(gene name synonym)|uniprotkb:hnRNP core protein A1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Leonard et al. (2003) pubmed:12927788 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1264"(NTNU) intact:EBI-9276665 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003585.3|ensembl:ENSP00000358478|refseq:XP_016858044.1|ensembl:ENSG00000116830(gene)|ensembl:ENST00000369466(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006397"(mRNA processing)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016787"(hydrolase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR010666(Zinc finger, GRF-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR038718|mint:Q9UNY4 refseq:NP_002127.1|refseq:NP_112420.1|ensembl:ENSG00000135486(gene)|ensembl:ENST00000340913(transcript)|ensembl:ENST00000677210(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|rcsb pdb:2LYV|rcsb pdb:2UP1|rcsb pdb:4YOE|rcsb pdb:5MPG|rcsb pdb:5MPL|rcsb pdb:5ZGD|rcsb pdb:5ZGL|rcsb pdb:6BXX|rcsb pdb:6DCL|rcsb pdb:6J60|rcsb pdb:7BX7|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035198"(miRNA binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051168"(nuclear export)|go:"GO:0051170"(import into nucleus)|go:"GO:0061752"(telomeric repeat-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1903936"(cellular response to sodium arsenite)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021662|interpro:IPR034803|interpro:IPR034845|interpro:IPR035979|mint:P09651|rcsb pdb:1HA1|rcsb pdb:1L3K|rcsb pdb:1PGZ|rcsb pdb:1PO6|rcsb pdb:1U1K|rcsb pdb:1U1L|rcsb pdb:1U1M|rcsb pdb:1U1N|rcsb pdb:1U1O|rcsb pdb:1U1P|rcsb pdb:1U1Q|rcsb pdb:1U1R|rcsb pdb:1UP1|rcsb pdb:2H4M|refseq:XP_005268883.1|dip:DIP-29338N - - - figure legend:Fig. 2A|curation depth:imex curation taxid:9606(human-ht1080)|taxid:9606(Homo sapiens HT1080 fribrosarcoma cell line) - 2014/03/22 2015/09/23 rogid:r4tIdwX2iegp6TXTVoLRPZnhN1A9606 rogid:ECXjsLRVtNc/aOw90tEFxowHc6c9606 intact-crc:DE36E49DCFFED9EB|rigid:exzAdJhvy+Vdf1s2jll5b3zXous false 35s radiolabel:?-? 35s radiolabel:?-? - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9UNY4 uniprotkb:O95239 intact:EBI-2322921|uniprotkb:A8K4Q2|uniprotkb:O75921|uniprotkb:Q5T2K7|uniprotkb:Q5VVU8|uniprotkb:Q8N6I8|intact:EBI-28970288|ensembl:ENSP00000358478 intact:EBI-1057516|uniprotkb:Q86TN3|uniprotkb:Q86XX7|uniprotkb:Q9NNY6|uniprotkb:Q9NY24|uniprotkb:Q9UMW3|uniprotkb:D3DVU4|uniprotkb:B2R7V5|ensembl:ENSP00000363524 psi-mi:ttf2_human(display_long)|uniprotkb:TTF2(gene name)|psi-mi:TTF2(display_short)|uniprotkb:RNA polymerase II termination factor(gene name synonym)|uniprotkb:Transcription release factor 2(gene name synonym)|uniprotkb:Lodestar homolog(gene name synonym) psi-mi:kif4a_human(display_long)|uniprotkb:KIF4A(gene name)|psi-mi:KIF4A(display_short)|uniprotkb:KIF4(gene name synonym)|uniprotkb:Chromokinesin-A(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Leonard et al. (2003) pubmed:12927788 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1264"(NTNU) intact:EBI-9276665 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003585.3|ensembl:ENSP00000358478|refseq:XP_016858044.1|ensembl:ENSG00000116830(gene)|ensembl:ENST00000369466(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006397"(mRNA processing)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016787"(hydrolase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR010666(Zinc finger, GRF-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR038718|mint:Q9UNY4 refseq:NP_036442.3|ensembl:ENSG00000090889(gene)|ensembl:ENST00000374403(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|interpro:IPR027417|interpro:IPR036961|mint:O95239|rcsb pdb:6OYL|reactome:R-HSA-2132295|reactome:R-HSA-437239|reactome:R-HSA-6811434|reactome:R-HSA-983189|go:"GO:0006996"(organelle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030496"(midbody)|go:"GO:0046872"(metal ion binding)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821 - - - figure legend:Fig. 2A|curation depth:imex curation taxid:9606(human-ht1080)|taxid:9606(Homo sapiens HT1080 fribrosarcoma cell line) - 2014/03/22 2015/09/23 rogid:r4tIdwX2iegp6TXTVoLRPZnhN1A9606 rogid:Dn015O/tY/LZAnI5oVnvTVQH3Zk9606 intact-crc:DE36E49DCFFED9EB|rigid:exzAdJhvy+Vdf1s2jll5b3zXous false 35s radiolabel:?-? 35s radiolabel:?-? - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9UNY4 uniprotkb:P22626 intact:EBI-2322921|uniprotkb:A8K4Q2|uniprotkb:O75921|uniprotkb:Q5T2K7|uniprotkb:Q5VVU8|uniprotkb:Q8N6I8|intact:EBI-28970288|ensembl:ENSP00000358478 intact:EBI-299649|ensembl:ENSP00000346694|ensembl:ENSP00000349101|ensembl:ENSP00000354021|ensembl:ENSP00000503360|ensembl:ENSP00000503476|ensembl:ENSP00000503514|ensembl:ENSP00000503885|ensembl:ENSP00000504329|uniprotkb:P22627|uniprotkb:A8K064|uniprotkb:Q9UC98|uniprotkb:Q9UDJ2|uniprotkb:A0A024RA27|uniprotkb:A0A024RA61 psi-mi:ttf2_human(display_long)|uniprotkb:TTF2(gene name)|psi-mi:TTF2(display_short)|uniprotkb:RNA polymerase II termination factor(gene name synonym)|uniprotkb:Transcription release factor 2(gene name synonym)|uniprotkb:Lodestar homolog(gene name synonym) psi-mi:roa2_human(display_long)|uniprotkb:HNRNPA2B1(gene name)|psi-mi:HNRNPA2B1(display_short)|uniprotkb:HNRPA2B1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Leonard et al. (2003) pubmed:12927788 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1264"(NTNU) intact:EBI-9276665 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003585.3|ensembl:ENSP00000358478|refseq:XP_016858044.1|ensembl:ENSG00000116830(gene)|ensembl:ENST00000369466(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006397"(mRNA processing)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016787"(hydrolase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR010666(Zinc finger, GRF-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR038718|mint:Q9UNY4 go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|ensembl:ENST00000679001(transcript)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0050658"(RNA transport)|ensembl:ENST00000679021(transcript)|go:"GO:0070062"(extracellular exosome)|ensembl:ENST00000679123(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1904358"(positive regulation of telomere maintenance via telomere lengthening)|go:"GO:1905663"(positive regulation of telomerase RNA reverse transcriptase activity)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|go:"GO:1990428"(miRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034486|interpro:IPR034489|interpro:IPR035979|mint:P22626|rcsb pdb:1X4B|rcsb pdb:5EN1|rcsb pdb:5HO4|rcsb pdb:5WWE|rcsb pdb:5WWF|rcsb pdb:5WWG|rcsb pdb:6WPQ|rcsb pdb:6WQK|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-8950505|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|ensembl:ENSG00000122566(gene)|ensembl:ENST00000354667(transcript)|ensembl:ENST00000356674(transcript)|ensembl:ENST00000360787(transcript)|ensembl:ENST00000676746(transcript)|ensembl:ENST00000678675(transcript)|refseq:NP_002128.1|refseq:NP_112533.1|dip:DIP-32877N|refseq:XP_005249786.1|refseq:XP_016867598.1|refseq:XP_016867599.1 - - - figure legend:Fig. 2A|curation depth:imex curation taxid:9606(human-ht1080)|taxid:9606(Homo sapiens HT1080 fribrosarcoma cell line) - 2014/03/22 2015/09/23 rogid:r4tIdwX2iegp6TXTVoLRPZnhN1A9606 rogid:N2NeJVio9eYQULNcdE1KXtd2KPw9606 intact-crc:DE36E49DCFFED9EB|rigid:exzAdJhvy+Vdf1s2jll5b3zXous false 35s radiolabel:?-? 35s radiolabel:?-? - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9UNY4 uniprotkb:P43243 intact:EBI-2322921|uniprotkb:A8K4Q2|uniprotkb:O75921|uniprotkb:Q5T2K7|uniprotkb:Q5VVU8|uniprotkb:Q8N6I8|intact:EBI-28970288|ensembl:ENSP00000358478 intact:EBI-352602|ensembl:ENSP00000378284|ensembl:ENSP00000482895|uniprotkb:Q9UHW0|uniprotkb:Q9UQ27|uniprotkb:D3DQC3|uniprotkb:B7ZAV5 psi-mi:ttf2_human(display_long)|uniprotkb:TTF2(gene name)|psi-mi:TTF2(display_short)|uniprotkb:RNA polymerase II termination factor(gene name synonym)|uniprotkb:Transcription release factor 2(gene name synonym)|uniprotkb:Lodestar homolog(gene name synonym) psi-mi:matr3_human(display_long)|uniprotkb:KIAA0723(gene name synonym)|uniprotkb:MATR3(gene name)|psi-mi:MATR3(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Leonard et al. (2003) pubmed:12927788 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1264"(NTNU) intact:EBI-9276665 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003585.3|ensembl:ENSP00000358478|refseq:XP_016858044.1|ensembl:ENSG00000116830(gene)|ensembl:ENST00000369466(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006397"(mRNA processing)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016787"(hydrolase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR010666(Zinc finger, GRF-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR038718|mint:Q9UNY4 ensembl:ENSG00000015479(gene)|ensembl:ENST00000394805(transcript)|ensembl:ENST00000618441(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003170"(heart valve development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034928|interpro:IPR034930|interpro:IPR035979|mint:P43243|refseq:NP_001181883.1|refseq:NP_001181884.1|refseq:NP_061322.2|refseq:NP_954659.1|refseq:NP_001181885.1|refseq:NP_001269207.1 - - - figure legend:Fig. 2A|curation depth:imex curation taxid:9606(human-ht1080)|taxid:9606(Homo sapiens HT1080 fribrosarcoma cell line) - 2014/03/22 2015/09/23 rogid:r4tIdwX2iegp6TXTVoLRPZnhN1A9606 rogid:3UZlyCZHgdr1SBgUctv9Ev7XBSQ9606 intact-crc:DE36E49DCFFED9EB|rigid:exzAdJhvy+Vdf1s2jll5b3zXous false 35s radiolabel:?-? 35s radiolabel:?-? - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q99459 uniprotkb:Q9UNY4 intact:EBI-374880|uniprotkb:Q76N46|uniprotkb:Q99974|ensembl:ENSP00000360532 intact:EBI-2322921|uniprotkb:A8K4Q2|uniprotkb:O75921|uniprotkb:Q5T2K7|uniprotkb:Q5VVU8|uniprotkb:Q8N6I8|intact:EBI-28970288|ensembl:ENSP00000358478 psi-mi:cdc5l_human(display_long)|uniprotkb:CDC5L(gene name)|psi-mi:CDC5L(display_short)|uniprotkb:Pombe cdc5-related protein(gene name synonym)|uniprotkb:KIAA0432(gene name synonym)|uniprotkb:PCDC5RP(gene name synonym) psi-mi:ttf2_human(display_long)|uniprotkb:TTF2(gene name)|psi-mi:TTF2(display_short)|uniprotkb:RNA polymerase II termination factor(gene name synonym)|uniprotkb:Transcription release factor 2(gene name synonym)|uniprotkb:Lodestar homolog(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Leonard et al. (2003) pubmed:12927788 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1264"(NTNU) intact:EBI-11225279 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|rcsb pdb:6ID1|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071352"(cellular response to interleukin-2)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904568"(cellular response to wortmannin)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990646"(cellular response to prolactin)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR021786|mint:Q99459|rcsb pdb:2DIM|rcsb pdb:2DIN|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|ensembl:ENSG00000096401(gene)|ensembl:ENST00000371477(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7AAV|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|refseq:NP_001244.1|dip:DIP-31731N refseq:NP_003585.3|ensembl:ENSP00000358478|refseq:XP_016858044.1|ensembl:ENSG00000116830(gene)|ensembl:ENST00000369466(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006397"(mRNA processing)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016787"(hydrolase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR010666(Zinc finger, GRF-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR038718|mint:Q9UNY4 - - - figure legend:Fig. 2B|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2014/03/22 2015/09/23 rogid:ZNRraJHn//46wKLSx7xtZju/lr09606 rogid:r4tIdwX2iegp6TXTVoLRPZnhN1A9606 rigid:wRU/kv6/TrFhRiX5NjpenvV/Yy8 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q99459 uniprotkb:Q9UNY4 intact:EBI-374880|uniprotkb:Q76N46|uniprotkb:Q99974|ensembl:ENSP00000360532 intact:EBI-2322921|uniprotkb:A8K4Q2|uniprotkb:O75921|uniprotkb:Q5T2K7|uniprotkb:Q5VVU8|uniprotkb:Q8N6I8|intact:EBI-28970288|ensembl:ENSP00000358478 psi-mi:cdc5l_human(display_long)|uniprotkb:CDC5L(gene name)|psi-mi:CDC5L(display_short)|uniprotkb:Pombe cdc5-related protein(gene name synonym)|uniprotkb:KIAA0432(gene name synonym)|uniprotkb:PCDC5RP(gene name synonym) psi-mi:ttf2_human(display_long)|uniprotkb:TTF2(gene name)|psi-mi:TTF2(display_short)|uniprotkb:RNA polymerase II termination factor(gene name synonym)|uniprotkb:Transcription release factor 2(gene name synonym)|uniprotkb:Lodestar homolog(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Leonard et al. (2003) pubmed:12927788 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1264"(NTNU) intact:EBI-11225474 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|rcsb pdb:6ID1|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071352"(cellular response to interleukin-2)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904568"(cellular response to wortmannin)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990646"(cellular response to prolactin)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR021786|mint:Q99459|rcsb pdb:2DIM|rcsb pdb:2DIN|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|ensembl:ENSG00000096401(gene)|ensembl:ENST00000371477(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7AAV|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|refseq:NP_001244.1|dip:DIP-31731N refseq:NP_003585.3|ensembl:ENSP00000358478|refseq:XP_016858044.1|ensembl:ENSG00000116830(gene)|ensembl:ENST00000369466(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006397"(mRNA processing)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016787"(hydrolase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR010666(Zinc finger, GRF-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR038718|mint:Q9UNY4 - - - figure legend:Fig. 2C|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2014/03/22 2015/09/23 rogid:ZNRraJHn//46wKLSx7xtZju/lr09606 rogid:r4tIdwX2iegp6TXTVoLRPZnhN1A9606 rigid:wRU/kv6/TrFhRiX5NjpenvV/Yy8 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q99459 uniprotkb:Q9UNY4 intact:EBI-374880|uniprotkb:Q76N46|uniprotkb:Q99974|ensembl:ENSP00000360532 intact:EBI-2322921|uniprotkb:A8K4Q2|uniprotkb:O75921|uniprotkb:Q5T2K7|uniprotkb:Q5VVU8|uniprotkb:Q8N6I8|intact:EBI-28970288|ensembl:ENSP00000358478 psi-mi:cdc5l_human(display_long)|uniprotkb:CDC5L(gene name)|psi-mi:CDC5L(display_short)|uniprotkb:Pombe cdc5-related protein(gene name synonym)|uniprotkb:KIAA0432(gene name synonym)|uniprotkb:PCDC5RP(gene name synonym) psi-mi:ttf2_human(display_long)|uniprotkb:TTF2(gene name)|psi-mi:TTF2(display_short)|uniprotkb:RNA polymerase II termination factor(gene name synonym)|uniprotkb:Transcription release factor 2(gene name synonym)|uniprotkb:Lodestar homolog(gene name synonym) psi-mi:"MI:0091"(chromatography technology) Leonard et al. (2003) pubmed:12927788 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1264"(NTNU) intact:EBI-11227021 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|rcsb pdb:6ID1|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071352"(cellular response to interleukin-2)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904568"(cellular response to wortmannin)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990646"(cellular response to prolactin)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR021786|mint:Q99459|rcsb pdb:2DIM|rcsb pdb:2DIN|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|ensembl:ENSG00000096401(gene)|ensembl:ENST00000371477(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7AAV|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|refseq:NP_001244.1|dip:DIP-31731N refseq:NP_003585.3|ensembl:ENSP00000358478|refseq:XP_016858044.1|ensembl:ENSG00000116830(gene)|ensembl:ENST00000369466(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006397"(mRNA processing)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016787"(hydrolase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR010666(Zinc finger, GRF-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR038718|mint:Q9UNY4 - - - figure legend:Fig. 2B|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2014/03/22 2015/09/23 rogid:ZNRraJHn//46wKLSx7xtZju/lr09606 rogid:r4tIdwX2iegp6TXTVoLRPZnhN1A9606 rigid:wRU/kv6/TrFhRiX5NjpenvV/Yy8 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)