#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P27958-PRO_0000037570 uniprotkb:Q8WTV0 intact:EBI-6904269 intact:EBI-78657|uniprotkb:Q52LZ5|uniprotkb:Q14016|uniprotkb:Q6KFX4|ensembl:ENSP00000414979|uniprotkb:F8W8N0 psi-mi:p27958-pro_0000037570(display_long) psi-mi:scrb1_human(display_long)|uniprotkb:SCARB1(gene name)|psi-mi:SCARB1(display_short)|uniprotkb:CD36L1(gene name synonym)|uniprotkb:CLA1(gene name synonym)|uniprotkb:SR-BI(gene name synonym)|uniprotkb:CD36 antigen-like 1(gene name synonym)|uniprotkb:CD36 and LIMPII analogous 1(gene name synonym)|uniprotkb:Collagen type I receptor, thrombospondin receptor-like 1(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Scarselli et al. (2002) pubmed:12356718|imex:IM-25956 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9163465|imex:IM-25956-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_005496.4|ensembl:ENSG00000073060(gene)|ensembl:ENST00000415380(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001875"(lipopolysaccharide immune receptor activity)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005215"(transporter activity)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006702"(androgen biosynthetic process)|go:"GO:0006707"(cholesterol catabolic process)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008289"(lipid binding)|go:"GO:0009986"(cell surface)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010867"(positive regulation of triglyceride biosynthetic process)|go:"GO:0010886"(positive regulation of cholesterol storage)|go:"GO:0010899"(regulation of phosphatidylcholine catabolic process)|go:"GO:0015914"(phospholipid transport)|go:"GO:0015920"(lipopolysaccharide transport)|go:"GO:0030169"(low-density lipoprotein particle binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0032497"(detection of lipopolysaccharide)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034186"(apolipoprotein A-I binding)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034381"(plasma lipoprotein particle clearance)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0034384"(high-density lipoprotein particle clearance)|go:"GO:0035461"(vitamin transmembrane transport)|go:"GO:0042060"(wound healing)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0043654"(recognition of apoptotic cell)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0044406"(adhesion of symbiont to host)|go:"GO:0050764"(regulation of phagocytosis)|go:"GO:0050892"(intestinal absorption)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070506"(high-density lipoprotein particle receptor activity)|go:"GO:0070508"(cholesterol import)|interpro:IPR002159(CD36 antigen)|interpro:IPR005428(Adhesion molecule CD36)|reactome:R-HSA-3000471|reactome:R-HSA-8964011|refseq:NP_001076428.1 - chain-seq-start:384|chain-seq-end:746 - figure legend:Fig. 4 and 5B|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hep_g2)|taxid:9606("Homo sapiens hepatocellular carcinoma (HCC) cells (p53-wt).") - 2014/02/10 2017/09/02 rogid:XFfKziasvR5/eMo+Xm/kI2cwpPc63746 rogid:En6dno+bRV4EB8FC539pcRRMIvs9606 intact-crc:2D1C49E31F15774A|rigid:YB0uu0GGgpnB38G9Apkf1X8st3o false his tag:?-? biotin tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8WTV0 uniprotkb:P27958-PRO_0000037570 intact:EBI-78657|uniprotkb:Q52LZ5|uniprotkb:Q14016|uniprotkb:Q6KFX4|ensembl:ENSP00000414979|uniprotkb:F8W8N0 intact:EBI-6904269 psi-mi:scrb1_human(display_long)|uniprotkb:SCARB1(gene name)|psi-mi:SCARB1(display_short)|uniprotkb:CD36L1(gene name synonym)|uniprotkb:CLA1(gene name synonym)|uniprotkb:SR-BI(gene name synonym)|uniprotkb:CD36 antigen-like 1(gene name synonym)|uniprotkb:CD36 and LIMPII analogous 1(gene name synonym)|uniprotkb:Collagen type I receptor, thrombospondin receptor-like 1(gene name synonym) psi-mi:p27958-pro_0000037570(display_long) psi-mi:"MI:0054"(fluorescence-activated cell sorting) Scarselli et al. (2002) pubmed:12356718|imex:IM-25956 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9163481|imex:IM-25956-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005496.4|ensembl:ENSG00000073060(gene)|ensembl:ENST00000415380(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001875"(lipopolysaccharide immune receptor activity)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005215"(transporter activity)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006702"(androgen biosynthetic process)|go:"GO:0006707"(cholesterol catabolic process)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008289"(lipid binding)|go:"GO:0009986"(cell surface)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010867"(positive regulation of triglyceride biosynthetic process)|go:"GO:0010886"(positive regulation of cholesterol storage)|go:"GO:0010899"(regulation of phosphatidylcholine catabolic process)|go:"GO:0015914"(phospholipid transport)|go:"GO:0015920"(lipopolysaccharide transport)|go:"GO:0030169"(low-density lipoprotein particle binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0032497"(detection of lipopolysaccharide)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034186"(apolipoprotein A-I binding)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034381"(plasma lipoprotein particle clearance)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0034384"(high-density lipoprotein particle clearance)|go:"GO:0035461"(vitamin transmembrane transport)|go:"GO:0042060"(wound healing)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0043654"(recognition of apoptotic cell)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0044406"(adhesion of symbiont to host)|go:"GO:0050764"(regulation of phagocytosis)|go:"GO:0050892"(intestinal absorption)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070506"(high-density lipoprotein particle receptor activity)|go:"GO:0070508"(cholesterol import)|interpro:IPR002159(CD36 antigen)|interpro:IPR005428(Adhesion molecule CD36)|reactome:R-HSA-3000471|reactome:R-HSA-8964011|refseq:NP_001076428.1 intact:EBI-706378(chain-parent) - - chain-seq-start:384|chain-seq-end:746 figure legend:Fig. 6B, 7 and 8|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line) - 2014/02/10 2014/10/16 rogid:En6dno+bRV4EB8FC539pcRRMIvs9606 rogid:XFfKziasvR5/eMo+Xm/kI2cwpPc63746 intact-crc:02DD65F94B6E43B3|rigid:YB0uu0GGgpnB38G9Apkf1X8st3o false - necessary binding region:1-27 - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:Q8WTV0 uniprotkb:P26663-PRO_0000037533 intact:EBI-78657|uniprotkb:Q52LZ5|uniprotkb:Q14016|uniprotkb:Q6KFX4|ensembl:ENSP00000414979|uniprotkb:F8W8N0 intact:EBI-9163492 psi-mi:scrb1_human(display_long)|uniprotkb:SCARB1(gene name)|psi-mi:SCARB1(display_short)|uniprotkb:CD36L1(gene name synonym)|uniprotkb:CLA1(gene name synonym)|uniprotkb:SR-BI(gene name synonym)|uniprotkb:CD36 antigen-like 1(gene name synonym)|uniprotkb:CD36 and LIMPII analogous 1(gene name synonym)|uniprotkb:Collagen type I receptor, thrombospondin receptor-like 1(gene name synonym) psi-mi:p26663-pro_0000037533(display_long) psi-mi:"MI:0054"(fluorescence-activated cell sorting) Scarselli et al. (2002) pubmed:12356718|imex:IM-25956 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:11105(hcvbk)|taxid:11105("Hepatitis C virus genotype 1b (isolate BK)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9163490|imex:IM-25956-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005496.4|ensembl:ENSG00000073060(gene)|ensembl:ENST00000415380(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001875"(lipopolysaccharide immune receptor activity)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005215"(transporter activity)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006702"(androgen biosynthetic process)|go:"GO:0006707"(cholesterol catabolic process)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008289"(lipid binding)|go:"GO:0009986"(cell surface)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010867"(positive regulation of triglyceride biosynthetic process)|go:"GO:0010886"(positive regulation of cholesterol storage)|go:"GO:0010899"(regulation of phosphatidylcholine catabolic process)|go:"GO:0015914"(phospholipid transport)|go:"GO:0015920"(lipopolysaccharide transport)|go:"GO:0030169"(low-density lipoprotein particle binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0032497"(detection of lipopolysaccharide)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034186"(apolipoprotein A-I binding)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034381"(plasma lipoprotein particle clearance)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0034384"(high-density lipoprotein particle clearance)|go:"GO:0035461"(vitamin transmembrane transport)|go:"GO:0042060"(wound healing)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0043654"(recognition of apoptotic cell)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0044406"(adhesion of symbiont to host)|go:"GO:0050764"(regulation of phagocytosis)|go:"GO:0050892"(intestinal absorption)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070506"(high-density lipoprotein particle receptor activity)|go:"GO:0070508"(cholesterol import)|interpro:IPR002159(CD36 antigen)|interpro:IPR005428(Adhesion molecule CD36)|reactome:R-HSA-3000471|reactome:R-HSA-8964011|refseq:NP_001076428.1 intact:EBI-6857429(chain-parent) - - chain-seq-start:384|chain-seq-end:746 figure legend:Fig. 6B, 7 and 8|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line) - 2014/02/10 2017/09/02 rogid:En6dno+bRV4EB8FC539pcRRMIvs9606 rogid:z06VT2CGSZr7NecUxj9+Rv9Afl011105 intact-crc:F8D2DB0657D7AF5A|rigid:JxnHXsDAj12uS+TMUA/qbjsqQew false - necessary binding region:1-27 - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody)