#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q6AY86 uniprotkb:G3V8A5 intact:EBI-9843441|ensembl:ENSRNOP00000062170 intact:EBI-9843458|ensembl:ENSRNOP00000024020 psi-mi:vp26a_rat(display_long)|uniprotkb:Vps26a(gene name)|psi-mi:Vps26a(display_short)|uniprotkb:Vps26(gene name synonym)|uniprotkb:Vesicle protein sorting 26A(gene name synonym) psi-mi:g3v8a5_rat(display_long)|uniprotkb:Vps35(gene name)|psi-mi:Vps35(display_short)|uniprotkb:Vps35_mapped(gene name synonym)|uniprotkb:rCG_44281(orf name) psi-mi:"MI:0029"(cosedimentation through density gradient) Haft et al. (2000) pubmed:11102511|imex:IM-23304 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-9843476|imex:IM-23304-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001007741.1|rgd:1359254|ensembl:ENSRNOG00000030683(gene)|ensembl:ENSRNOT00000067883(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031982"(vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0097422"(tubular endosome)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR028934|reactome:R-RNO-3238698 refseq:NP_001099188.2|rgd:1589784|ensembl:ENSRNOG00000017612(gene)|ensembl:ENSRNOT00000024020(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007416"(synapse assembly)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032463"(negative regulation of protein homooligomerization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090326"(positive regulation of locomotion involved in locomotory behavior)|go:"GO:0097422"(tubular endosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903181"(positive regulation of dopamine biosynthetic process)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903828"(negative regulation of protein localization)|go:"GO:1905166"(negative regulation of lysosomal protein catabolic process)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|reactome:R-RNO-3238698 - - - figure legend:4C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2014/10/10 2014/10/16 rogid:Rawqvx7w912A1Mq74mEF2bONzdY10116 rogid:9H/8n7q9kWa918SPxTMzp9xRek810116 intact-crc:3BDD05D7DDDFFA33|rigid:billM1aBnH3+xmEnjXT/qsFc0bk false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O75436 uniprotkb:Q96QK1 intact:EBI-1043891|uniprotkb:Q8TBH4|uniprotkb:Q9H982|ensembl:ENSP00000263559|ensembl:ENSP00000362480|uniprotkb:B2RDD3|uniprotkb:A8MZ56 intact:EBI-1054634|uniprotkb:Q561W2|uniprotkb:Q9H016|uniprotkb:Q9H096|uniprotkb:Q9H4P3|uniprotkb:Q9H8J0|uniprotkb:Q9NRS7|uniprotkb:Q9NVG2|uniprotkb:Q9NX80|uniprotkb:Q9NZK2|ensembl:ENSP00000299138 psi-mi:vp26a_human(display_long)|uniprotkb:VPS26A(gene name)|psi-mi:VPS26A(display_short)|uniprotkb:VPS26(gene name synonym)|uniprotkb:Vesicle protein sorting 26A(gene name synonym) psi-mi:vps35_human(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:VPS35(gene name)|psi-mi:VPS35(display_short)|uniprotkb:MEM3(gene name synonym)|uniprotkb:TCCCTA00141(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Haft et al. (2000) pubmed:11102511|imex:IM-23304 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9918358|imex:IM-23304-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000122958(gene)|ensembl:ENST00000263559(transcript)|ensembl:ENST00000373382(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031982"(vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0097422"(tubular endosome)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR028934|mint:O75436|rcsb pdb:2FAU|rcsb pdb:5F0J|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|reactome:R-HSA-3238698|rcsb pdb:7BLO|refseq:NP_001030337.1|refseq:NP_004887.2|refseq:NP_001305875.1|dip:DIP-29075N refseq:NP_060676.2|rcsb pdb:5F0J|rcsb pdb:5F0K|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|rcsb pdb:5OSH|rcsb pdb:5OSI|rcsb pdb:7BLN|rcsb pdb:7BLO|reactome:R-HSA-3238698|ensembl:ENSG00000069329(gene)|ensembl:ENST00000299138(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0097422"(tubular endosome)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|rcsb pdb:2R17|dip:DIP-29076N - - - figure legend:5A lane 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2014/10/10 2014/11/18 rogid:n0uOd+2HQmRW7koIy678uP0d3+o9606 rogid:EXkMduDQKNCdp876vGF5vna9t389606 intact-crc:4A88F41BBE261093|rigid:GyW9633bdSt0TW9Pfbxyxu1Qcoc false myc tag:n-n myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O75436 uniprotkb:Q96QK1 intact:EBI-1043891|uniprotkb:Q8TBH4|uniprotkb:Q9H982|ensembl:ENSP00000263559|ensembl:ENSP00000362480|uniprotkb:B2RDD3|uniprotkb:A8MZ56 intact:EBI-1054634|uniprotkb:Q561W2|uniprotkb:Q9H016|uniprotkb:Q9H096|uniprotkb:Q9H4P3|uniprotkb:Q9H8J0|uniprotkb:Q9NRS7|uniprotkb:Q9NVG2|uniprotkb:Q9NX80|uniprotkb:Q9NZK2|ensembl:ENSP00000299138 psi-mi:vp26a_human(display_long)|uniprotkb:VPS26A(gene name)|psi-mi:VPS26A(display_short)|uniprotkb:VPS26(gene name synonym)|uniprotkb:Vesicle protein sorting 26A(gene name synonym) psi-mi:vps35_human(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:VPS35(gene name)|psi-mi:VPS35(display_short)|uniprotkb:MEM3(gene name synonym)|uniprotkb:TCCCTA00141(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Haft et al. (2000) pubmed:11102511|imex:IM-23304 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-9918381|imex:IM-23304-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000122958(gene)|ensembl:ENST00000263559(transcript)|ensembl:ENST00000373382(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031982"(vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0097422"(tubular endosome)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR028934|mint:O75436|rcsb pdb:2FAU|rcsb pdb:5F0J|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|reactome:R-HSA-3238698|rcsb pdb:7BLO|refseq:NP_001030337.1|refseq:NP_004887.2|refseq:NP_001305875.1|dip:DIP-29075N refseq:NP_060676.2|rcsb pdb:5F0J|rcsb pdb:5F0K|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|rcsb pdb:5OSH|rcsb pdb:5OSI|rcsb pdb:7BLN|rcsb pdb:7BLO|reactome:R-HSA-3238698|ensembl:ENSG00000069329(gene)|ensembl:ENST00000299138(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0097422"(tubular endosome)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|rcsb pdb:2R17|dip:DIP-29076N - - - figure legend:5A lane 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2014/10/10 2014/11/04 rogid:n0uOd+2HQmRW7koIy678uP0d3+o9606 rogid:EXkMduDQKNCdp876vGF5vna9t389606 intact-crc:8083254F586A0A3A|rigid:/o6lDSAUYfP4GHwqnJ1dAQi9JiE false myc tag:n-n myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O75436 uniprotkb:Q9UBQ0 intact:EBI-1043891|uniprotkb:Q8TBH4|uniprotkb:Q9H982|ensembl:ENSP00000263559|ensembl:ENSP00000362480|uniprotkb:B2RDD3|uniprotkb:A8MZ56 intact:EBI-718596|uniprotkb:Q502Y5|uniprotkb:Q9H0W0|uniprotkb:Q9NRP1|uniprotkb:Q6FIF8|uniprotkb:Q6IAH3|uniprotkb:Q9NRU7|ensembl:ENSP00000447058 psi-mi:vp26a_human(display_long)|uniprotkb:VPS26A(gene name)|psi-mi:VPS26A(display_short)|uniprotkb:VPS26(gene name synonym)|uniprotkb:Vesicle protein sorting 26A(gene name synonym) psi-mi:vps29_human(display_long)|uniprotkb:Vesicle protein sorting 29(gene name synonym)|uniprotkb:PEP11 homolog(gene name synonym)|uniprotkb:VPS29(gene name)|psi-mi:VPS29(display_short)|uniprotkb:DC7(orf name)|uniprotkb:DC15(orf name)|uniprotkb:MDS007(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Haft et al. (2000) pubmed:11102511|imex:IM-23304 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-9918381|imex:IM-23304-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000122958(gene)|ensembl:ENST00000263559(transcript)|ensembl:ENST00000373382(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031982"(vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0097422"(tubular endosome)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR028934|mint:O75436|rcsb pdb:2FAU|rcsb pdb:5F0J|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|reactome:R-HSA-3238698|rcsb pdb:7BLO|refseq:NP_001030337.1|refseq:NP_004887.2|refseq:NP_001305875.1|dip:DIP-29075N refseq:NP_057310.1|refseq:NP_476528.1|ensembl:ENSG00000111237(gene)|ensembl:ENST00000549578(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|rcsb pdb:1W24|rcsb pdb:2R17|rcsb pdb:5GTU|rcsb pdb:5OSH|rcsb pdb:5OSI|rcsb pdb:5WYH|rcsb pdb:7BLN|reactome:R-HSA-3238698|dip:DIP-29077N - - - figure legend:5A lane 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2014/10/10 2014/11/04 rogid:n0uOd+2HQmRW7koIy678uP0d3+o9606 rogid:xjo28jAH7expkdli0DENjzLXpjw9606 intact-crc:8083254F586A0A3A|rigid:/o6lDSAUYfP4GHwqnJ1dAQi9JiE false myc tag:n-n myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O75436 uniprotkb:Q13596 intact:EBI-1043891|uniprotkb:Q8TBH4|uniprotkb:Q9H982|ensembl:ENSP00000263559|ensembl:ENSP00000362480|uniprotkb:B2RDD3|uniprotkb:A8MZ56 intact:EBI-2822329|uniprotkb:O60750|uniprotkb:A8K6T7|uniprotkb:A6NM19|uniprotkb:O60751|uniprotkb:H0Y2M5|uniprotkb:Q6ZRJ8|ensembl:ENSP00000453785 psi-mi:vp26a_human(display_long)|uniprotkb:VPS26A(gene name)|psi-mi:VPS26A(display_short)|uniprotkb:VPS26(gene name synonym)|uniprotkb:Vesicle protein sorting 26A(gene name synonym) psi-mi:snx1_human(display_long)|uniprotkb:SNX1(gene name)|psi-mi:SNX1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Haft et al. (2000) pubmed:11102511|imex:IM-23304 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-9843489|imex:IM-23304-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000122958(gene)|ensembl:ENST00000263559(transcript)|ensembl:ENST00000373382(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031982"(vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0097422"(tubular endosome)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR028934|mint:O75436|rcsb pdb:2FAU|rcsb pdb:5F0J|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|reactome:R-HSA-3238698|rcsb pdb:7BLO|refseq:NP_001030337.1|refseq:NP_004887.2|refseq:NP_001305875.1|dip:DIP-29075N refseq:NP_003090.2|refseq:NP_683758.1|refseq:NP_001229862.1|ensembl:ENSG00000028528(gene)|ensembl:ENST00000559844(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030904"(retromer complex)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0031623"(receptor internalization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0072673"(lamellipodium morphogenesis)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990460"(leptin receptor binding)|interpro:IPR001683(Phox-like)|interpro:IPR005329(Sorting nexin, N-terminal)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028660|interpro:IPR034901|mint:Q13596|rcsb pdb:2I4K|rcsb pdb:4FZS|interpro:IPR036871|dip:DIP-398N - - - figure legend:5A lane 7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2014/10/10 2014/11/04 rogid:n0uOd+2HQmRW7koIy678uP0d3+o9606 rogid:nFyxCtQ9gHndLbuCjBiwhyWE5do9606 intact-crc:FF825471C1B1FB4C|rigid:XDenssr43GvWcFAblqemlusGkwU false myc tag:n-n myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O75436 uniprotkb:Q96QK1 intact:EBI-1043891|uniprotkb:Q8TBH4|uniprotkb:Q9H982|ensembl:ENSP00000263559|ensembl:ENSP00000362480|uniprotkb:B2RDD3|uniprotkb:A8MZ56 intact:EBI-1054634|uniprotkb:Q561W2|uniprotkb:Q9H016|uniprotkb:Q9H096|uniprotkb:Q9H4P3|uniprotkb:Q9H8J0|uniprotkb:Q9NRS7|uniprotkb:Q9NVG2|uniprotkb:Q9NX80|uniprotkb:Q9NZK2|ensembl:ENSP00000299138 psi-mi:vp26a_human(display_long)|uniprotkb:VPS26A(gene name)|psi-mi:VPS26A(display_short)|uniprotkb:VPS26(gene name synonym)|uniprotkb:Vesicle protein sorting 26A(gene name synonym) psi-mi:vps35_human(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:VPS35(gene name)|psi-mi:VPS35(display_short)|uniprotkb:MEM3(gene name synonym)|uniprotkb:TCCCTA00141(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Haft et al. (2000) pubmed:11102511|imex:IM-23304 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-9843489|imex:IM-23304-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000122958(gene)|ensembl:ENST00000263559(transcript)|ensembl:ENST00000373382(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031982"(vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0097422"(tubular endosome)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR028934|mint:O75436|rcsb pdb:2FAU|rcsb pdb:5F0J|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|reactome:R-HSA-3238698|rcsb pdb:7BLO|refseq:NP_001030337.1|refseq:NP_004887.2|refseq:NP_001305875.1|dip:DIP-29075N refseq:NP_060676.2|rcsb pdb:5F0J|rcsb pdb:5F0K|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|rcsb pdb:5OSH|rcsb pdb:5OSI|rcsb pdb:7BLN|rcsb pdb:7BLO|reactome:R-HSA-3238698|ensembl:ENSG00000069329(gene)|ensembl:ENST00000299138(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0097422"(tubular endosome)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|rcsb pdb:2R17|dip:DIP-29076N - - - figure legend:5A lane 7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2014/10/10 2014/11/04 rogid:n0uOd+2HQmRW7koIy678uP0d3+o9606 rogid:EXkMduDQKNCdp876vGF5vna9t389606 intact-crc:FF825471C1B1FB4C|rigid:XDenssr43GvWcFAblqemlusGkwU false myc tag:n-n myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O75436 uniprotkb:Q9UBQ0 intact:EBI-1043891|uniprotkb:Q8TBH4|uniprotkb:Q9H982|ensembl:ENSP00000263559|ensembl:ENSP00000362480|uniprotkb:B2RDD3|uniprotkb:A8MZ56 intact:EBI-718596|uniprotkb:Q502Y5|uniprotkb:Q9H0W0|uniprotkb:Q9NRP1|uniprotkb:Q6FIF8|uniprotkb:Q6IAH3|uniprotkb:Q9NRU7|ensembl:ENSP00000447058 psi-mi:vp26a_human(display_long)|uniprotkb:VPS26A(gene name)|psi-mi:VPS26A(display_short)|uniprotkb:VPS26(gene name synonym)|uniprotkb:Vesicle protein sorting 26A(gene name synonym) psi-mi:vps29_human(display_long)|uniprotkb:Vesicle protein sorting 29(gene name synonym)|uniprotkb:PEP11 homolog(gene name synonym)|uniprotkb:VPS29(gene name)|psi-mi:VPS29(display_short)|uniprotkb:DC7(orf name)|uniprotkb:DC15(orf name)|uniprotkb:MDS007(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Haft et al. (2000) pubmed:11102511|imex:IM-23304 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-9843489|imex:IM-23304-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000122958(gene)|ensembl:ENST00000263559(transcript)|ensembl:ENST00000373382(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031982"(vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0097422"(tubular endosome)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR028934|mint:O75436|rcsb pdb:2FAU|rcsb pdb:5F0J|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|reactome:R-HSA-3238698|rcsb pdb:7BLO|refseq:NP_001030337.1|refseq:NP_004887.2|refseq:NP_001305875.1|dip:DIP-29075N refseq:NP_057310.1|refseq:NP_476528.1|ensembl:ENSG00000111237(gene)|ensembl:ENST00000549578(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|rcsb pdb:1W24|rcsb pdb:2R17|rcsb pdb:5GTU|rcsb pdb:5OSH|rcsb pdb:5OSI|rcsb pdb:5WYH|rcsb pdb:7BLN|reactome:R-HSA-3238698|dip:DIP-29077N - - - figure legend:5A lane 7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2014/10/10 2014/11/04 rogid:n0uOd+2HQmRW7koIy678uP0d3+o9606 rogid:xjo28jAH7expkdli0DENjzLXpjw9606 intact-crc:FF825471C1B1FB4C|rigid:XDenssr43GvWcFAblqemlusGkwU false myc tag:n-n myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O75436 uniprotkb:Q9UBQ0 intact:EBI-1043891|uniprotkb:Q8TBH4|uniprotkb:Q9H982|ensembl:ENSP00000263559|ensembl:ENSP00000362480|uniprotkb:B2RDD3|uniprotkb:A8MZ56 intact:EBI-718596|uniprotkb:Q502Y5|uniprotkb:Q9H0W0|uniprotkb:Q9NRP1|uniprotkb:Q6FIF8|uniprotkb:Q6IAH3|uniprotkb:Q9NRU7|ensembl:ENSP00000447058 psi-mi:vp26a_human(display_long)|uniprotkb:VPS26A(gene name)|psi-mi:VPS26A(display_short)|uniprotkb:VPS26(gene name synonym)|uniprotkb:Vesicle protein sorting 26A(gene name synonym) psi-mi:vps29_human(display_long)|uniprotkb:Vesicle protein sorting 29(gene name synonym)|uniprotkb:PEP11 homolog(gene name synonym)|uniprotkb:VPS29(gene name)|psi-mi:VPS29(display_short)|uniprotkb:DC7(orf name)|uniprotkb:DC15(orf name)|uniprotkb:MDS007(orf name) psi-mi:"MI:0071"(molecular sieving) Haft et al. (2000) pubmed:11102511|imex:IM-23304 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9915776|imex:IM-23304-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000122958(gene)|ensembl:ENST00000263559(transcript)|ensembl:ENST00000373382(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031982"(vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0097422"(tubular endosome)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR028934|mint:O75436|rcsb pdb:2FAU|rcsb pdb:5F0J|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|reactome:R-HSA-3238698|rcsb pdb:7BLO|refseq:NP_001030337.1|refseq:NP_004887.2|refseq:NP_001305875.1|dip:DIP-29075N refseq:NP_057310.1|refseq:NP_476528.1|ensembl:ENSG00000111237(gene)|ensembl:ENST00000549578(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|rcsb pdb:1W24|rcsb pdb:2R17|rcsb pdb:5GTU|rcsb pdb:5OSH|rcsb pdb:5OSI|rcsb pdb:5WYH|rcsb pdb:7BLN|reactome:R-HSA-3238698|dip:DIP-29077N - - - figure legend:7A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2014/10/10 2014/11/04 rogid:n0uOd+2HQmRW7koIy678uP0d3+o9606 rogid:xjo28jAH7expkdli0DENjzLXpjw9606 intact-crc:5C199012F981CF61|rigid:vtMu18xaOo8ZLUEaU8YoRPyEyj0 false myc tag:n-n myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O60749 uniprotkb:O75436 intact:EBI-1046690|uniprotkb:O43650|uniprotkb:P82862|uniprotkb:Q53XK8|uniprotkb:Q597H6|uniprotkb:Q9BTS8|ensembl:ENSP00000368831|uniprotkb:B3KN44|uniprotkb:B4DEK4|uniprotkb:B7Z408 intact:EBI-1043891|uniprotkb:Q8TBH4|uniprotkb:Q9H982|ensembl:ENSP00000263559|ensembl:ENSP00000362480|uniprotkb:B2RDD3|uniprotkb:A8MZ56 psi-mi:snx2_human(display_long)|uniprotkb:Transformation-related gene 9 protein(gene name synonym)|uniprotkb:SNX2(gene name)|psi-mi:SNX2(display_short)|uniprotkb:TRG9(orf name) psi-mi:vp26a_human(display_long)|uniprotkb:VPS26A(gene name)|psi-mi:VPS26A(display_short)|uniprotkb:VPS26(gene name synonym)|uniprotkb:Vesicle protein sorting 26A(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Haft et al. (2000) pubmed:11102511|imex:IM-23304 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9843521|imex:IM-23304-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003091.2|ensembl:ENSG00000205302(gene)|ensembl:ENST00000379516(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030904"(retromer complex)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0072673"(lamellipodium morphogenesis)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990460"(leptin receptor binding)|interpro:IPR001683(Phox-like)|interpro:IPR005329(Sorting nexin, N-terminal)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028653|interpro:IPR037918|mint:O60749|interpro:IPR036871|reactome:R-HSA-432722|refseq:NP_001265128.1 ensembl:ENSG00000122958(gene)|ensembl:ENST00000263559(transcript)|ensembl:ENST00000373382(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031982"(vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0097422"(tubular endosome)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR028934|mint:O75436|rcsb pdb:2FAU|rcsb pdb:5F0J|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|reactome:R-HSA-3238698|rcsb pdb:7BLO|refseq:NP_001030337.1|refseq:NP_004887.2|refseq:NP_001305875.1|dip:DIP-29075N go:"GO:0005829"(cytosol) - - figure legend:6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2014/10/10 2014/11/03 rogid:Sb/i4ZNGqy+ixeexnp0/4uOo3jo9606 rogid:n0uOd+2HQmRW7koIy678uP0d3+o9606 intact-crc:E9BE0D40823745FD|rigid:JMGLAXqC+30G8jjjg8zbDfU7TLM false myc tag:n-n myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O60749 uniprotkb:Q9UBQ0 intact:EBI-1046690|uniprotkb:O43650|uniprotkb:P82862|uniprotkb:Q53XK8|uniprotkb:Q597H6|uniprotkb:Q9BTS8|ensembl:ENSP00000368831|uniprotkb:B3KN44|uniprotkb:B4DEK4|uniprotkb:B7Z408 intact:EBI-718596|uniprotkb:Q502Y5|uniprotkb:Q9H0W0|uniprotkb:Q9NRP1|uniprotkb:Q6FIF8|uniprotkb:Q6IAH3|uniprotkb:Q9NRU7|ensembl:ENSP00000447058 psi-mi:snx2_human(display_long)|uniprotkb:Transformation-related gene 9 protein(gene name synonym)|uniprotkb:SNX2(gene name)|psi-mi:SNX2(display_short)|uniprotkb:TRG9(orf name) psi-mi:vps29_human(display_long)|uniprotkb:Vesicle protein sorting 29(gene name synonym)|uniprotkb:PEP11 homolog(gene name synonym)|uniprotkb:VPS29(gene name)|psi-mi:VPS29(display_short)|uniprotkb:DC7(orf name)|uniprotkb:DC15(orf name)|uniprotkb:MDS007(orf name) psi-mi:"MI:0071"(molecular sieving) Haft et al. (2000) pubmed:11102511|imex:IM-23304 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9843521|imex:IM-23304-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003091.2|ensembl:ENSG00000205302(gene)|ensembl:ENST00000379516(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030904"(retromer complex)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0072673"(lamellipodium morphogenesis)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990460"(leptin receptor binding)|interpro:IPR001683(Phox-like)|interpro:IPR005329(Sorting nexin, N-terminal)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028653|interpro:IPR037918|mint:O60749|interpro:IPR036871|reactome:R-HSA-432722|refseq:NP_001265128.1 refseq:NP_057310.1|refseq:NP_476528.1|ensembl:ENSG00000111237(gene)|ensembl:ENST00000549578(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|rcsb pdb:1W24|rcsb pdb:2R17|rcsb pdb:5GTU|rcsb pdb:5OSH|rcsb pdb:5OSI|rcsb pdb:5WYH|rcsb pdb:7BLN|reactome:R-HSA-3238698|dip:DIP-29077N go:"GO:0005829"(cytosol) - - figure legend:6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2014/10/10 2014/11/03 rogid:Sb/i4ZNGqy+ixeexnp0/4uOo3jo9606 rogid:xjo28jAH7expkdli0DENjzLXpjw9606 intact-crc:E9BE0D40823745FD|rigid:JMGLAXqC+30G8jjjg8zbDfU7TLM false myc tag:n-n myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O60749 uniprotkb:Q96QK1 intact:EBI-1046690|uniprotkb:O43650|uniprotkb:P82862|uniprotkb:Q53XK8|uniprotkb:Q597H6|uniprotkb:Q9BTS8|ensembl:ENSP00000368831|uniprotkb:B3KN44|uniprotkb:B4DEK4|uniprotkb:B7Z408 intact:EBI-1054634|uniprotkb:Q561W2|uniprotkb:Q9H016|uniprotkb:Q9H096|uniprotkb:Q9H4P3|uniprotkb:Q9H8J0|uniprotkb:Q9NRS7|uniprotkb:Q9NVG2|uniprotkb:Q9NX80|uniprotkb:Q9NZK2|ensembl:ENSP00000299138 psi-mi:snx2_human(display_long)|uniprotkb:Transformation-related gene 9 protein(gene name synonym)|uniprotkb:SNX2(gene name)|psi-mi:SNX2(display_short)|uniprotkb:TRG9(orf name) psi-mi:vps35_human(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:VPS35(gene name)|psi-mi:VPS35(display_short)|uniprotkb:MEM3(gene name synonym)|uniprotkb:TCCCTA00141(orf name) psi-mi:"MI:0071"(molecular sieving) Haft et al. (2000) pubmed:11102511|imex:IM-23304 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9843521|imex:IM-23304-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003091.2|ensembl:ENSG00000205302(gene)|ensembl:ENST00000379516(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030904"(retromer complex)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0072673"(lamellipodium morphogenesis)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990460"(leptin receptor binding)|interpro:IPR001683(Phox-like)|interpro:IPR005329(Sorting nexin, N-terminal)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028653|interpro:IPR037918|mint:O60749|interpro:IPR036871|reactome:R-HSA-432722|refseq:NP_001265128.1 refseq:NP_060676.2|rcsb pdb:5F0J|rcsb pdb:5F0K|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|rcsb pdb:5OSH|rcsb pdb:5OSI|rcsb pdb:7BLN|rcsb pdb:7BLO|reactome:R-HSA-3238698|ensembl:ENSG00000069329(gene)|ensembl:ENST00000299138(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0097422"(tubular endosome)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|rcsb pdb:2R17|dip:DIP-29076N go:"GO:0005829"(cytosol) - - figure legend:6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2014/10/10 2014/11/03 rogid:Sb/i4ZNGqy+ixeexnp0/4uOo3jo9606 rogid:EXkMduDQKNCdp876vGF5vna9t389606 intact-crc:E9BE0D40823745FD|rigid:JMGLAXqC+30G8jjjg8zbDfU7TLM false myc tag:n-n myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O75436 uniprotkb:Q9UBQ0 intact:EBI-1043891|uniprotkb:Q8TBH4|uniprotkb:Q9H982|ensembl:ENSP00000263559|ensembl:ENSP00000362480|uniprotkb:B2RDD3|uniprotkb:A8MZ56 intact:EBI-718596|uniprotkb:Q502Y5|uniprotkb:Q9H0W0|uniprotkb:Q9NRP1|uniprotkb:Q6FIF8|uniprotkb:Q6IAH3|uniprotkb:Q9NRU7|ensembl:ENSP00000447058 psi-mi:vp26a_human(display_long)|uniprotkb:VPS26A(gene name)|psi-mi:VPS26A(display_short)|uniprotkb:VPS26(gene name synonym)|uniprotkb:Vesicle protein sorting 26A(gene name synonym) psi-mi:vps29_human(display_long)|uniprotkb:Vesicle protein sorting 29(gene name synonym)|uniprotkb:PEP11 homolog(gene name synonym)|uniprotkb:VPS29(gene name)|psi-mi:VPS29(display_short)|uniprotkb:DC7(orf name)|uniprotkb:DC15(orf name)|uniprotkb:MDS007(orf name) psi-mi:"MI:0071"(molecular sieving) Haft et al. (2000) pubmed:11102511|imex:IM-23304 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9979409|imex:IM-23304-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000122958(gene)|ensembl:ENST00000263559(transcript)|ensembl:ENST00000373382(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031982"(vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0097422"(tubular endosome)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR028934|mint:O75436|rcsb pdb:2FAU|rcsb pdb:5F0J|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|reactome:R-HSA-3238698|rcsb pdb:7BLO|refseq:NP_001030337.1|refseq:NP_004887.2|refseq:NP_001305875.1|dip:DIP-29075N refseq:NP_057310.1|refseq:NP_476528.1|ensembl:ENSG00000111237(gene)|ensembl:ENST00000549578(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|rcsb pdb:1W24|rcsb pdb:2R17|rcsb pdb:5GTU|rcsb pdb:5OSH|rcsb pdb:5OSI|rcsb pdb:5WYH|rcsb pdb:7BLN|reactome:R-HSA-3238698|dip:DIP-29077N - - - figure legend:7D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2014/10/10 2014/11/18 rogid:n0uOd+2HQmRW7koIy678uP0d3+o9606 rogid:xjo28jAH7expkdli0DENjzLXpjw9606 intact-crc:DF869ED8C7DFD0D7|rigid:/o6lDSAUYfP4GHwqnJ1dAQi9JiE false myc tag:n-n myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O75436 uniprotkb:Q96QK1 intact:EBI-1043891|uniprotkb:Q8TBH4|uniprotkb:Q9H982|ensembl:ENSP00000263559|ensembl:ENSP00000362480|uniprotkb:B2RDD3|uniprotkb:A8MZ56 intact:EBI-1054634|uniprotkb:Q561W2|uniprotkb:Q9H016|uniprotkb:Q9H096|uniprotkb:Q9H4P3|uniprotkb:Q9H8J0|uniprotkb:Q9NRS7|uniprotkb:Q9NVG2|uniprotkb:Q9NX80|uniprotkb:Q9NZK2|ensembl:ENSP00000299138 psi-mi:vp26a_human(display_long)|uniprotkb:VPS26A(gene name)|psi-mi:VPS26A(display_short)|uniprotkb:VPS26(gene name synonym)|uniprotkb:Vesicle protein sorting 26A(gene name synonym) psi-mi:vps35_human(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:VPS35(gene name)|psi-mi:VPS35(display_short)|uniprotkb:MEM3(gene name synonym)|uniprotkb:TCCCTA00141(orf name) psi-mi:"MI:0071"(molecular sieving) Haft et al. (2000) pubmed:11102511|imex:IM-23304 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9979409|imex:IM-23304-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000122958(gene)|ensembl:ENST00000263559(transcript)|ensembl:ENST00000373382(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031982"(vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0097422"(tubular endosome)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR028934|mint:O75436|rcsb pdb:2FAU|rcsb pdb:5F0J|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|reactome:R-HSA-3238698|rcsb pdb:7BLO|refseq:NP_001030337.1|refseq:NP_004887.2|refseq:NP_001305875.1|dip:DIP-29075N refseq:NP_060676.2|rcsb pdb:5F0J|rcsb pdb:5F0K|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|rcsb pdb:5OSH|rcsb pdb:5OSI|rcsb pdb:7BLN|rcsb pdb:7BLO|reactome:R-HSA-3238698|ensembl:ENSG00000069329(gene)|ensembl:ENST00000299138(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0097422"(tubular endosome)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|rcsb pdb:2R17|dip:DIP-29076N - - - figure legend:7D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2014/10/10 2014/11/18 rogid:n0uOd+2HQmRW7koIy678uP0d3+o9606 rogid:EXkMduDQKNCdp876vGF5vna9t389606 intact-crc:DF869ED8C7DFD0D7|rigid:/o6lDSAUYfP4GHwqnJ1dAQi9JiE false myc tag:n-n myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q13596 uniprotkb:O75436 intact:EBI-2822329|uniprotkb:O60750|uniprotkb:A8K6T7|uniprotkb:A6NM19|uniprotkb:O60751|uniprotkb:H0Y2M5|uniprotkb:Q6ZRJ8|ensembl:ENSP00000453785 intact:EBI-1043891|uniprotkb:Q8TBH4|uniprotkb:Q9H982|ensembl:ENSP00000263559|ensembl:ENSP00000362480|uniprotkb:B2RDD3|uniprotkb:A8MZ56 psi-mi:snx1_human(display_long)|uniprotkb:SNX1(gene name)|psi-mi:SNX1(display_short) psi-mi:vp26a_human(display_long)|uniprotkb:VPS26A(gene name)|psi-mi:VPS26A(display_short)|uniprotkb:VPS26(gene name synonym)|uniprotkb:Vesicle protein sorting 26A(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Haft et al. (2000) pubmed:11102511|imex:IM-23304 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9843548|imex:IM-23304-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003090.2|refseq:NP_683758.1|refseq:NP_001229862.1|ensembl:ENSG00000028528(gene)|ensembl:ENST00000559844(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030904"(retromer complex)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0031623"(receptor internalization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0072673"(lamellipodium morphogenesis)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990460"(leptin receptor binding)|interpro:IPR001683(Phox-like)|interpro:IPR005329(Sorting nexin, N-terminal)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028660|interpro:IPR034901|mint:Q13596|rcsb pdb:2I4K|rcsb pdb:4FZS|interpro:IPR036871|dip:DIP-398N ensembl:ENSG00000122958(gene)|ensembl:ENST00000263559(transcript)|ensembl:ENST00000373382(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031982"(vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0097422"(tubular endosome)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR028934|mint:O75436|rcsb pdb:2FAU|rcsb pdb:5F0J|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|reactome:R-HSA-3238698|rcsb pdb:7BLO|refseq:NP_001030337.1|refseq:NP_004887.2|refseq:NP_001305875.1|dip:DIP-29075N - - - figure legend:8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2014/10/10 2014/11/18 rogid:nFyxCtQ9gHndLbuCjBiwhyWE5do9606 rogid:n0uOd+2HQmRW7koIy678uP0d3+o9606 intact-crc:1DC429C78775A1DB|rigid:XDenssr43GvWcFAblqemlusGkwU false myc tag:n-n myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q13596 uniprotkb:Q9UBQ0 intact:EBI-2822329|uniprotkb:O60750|uniprotkb:A8K6T7|uniprotkb:A6NM19|uniprotkb:O60751|uniprotkb:H0Y2M5|uniprotkb:Q6ZRJ8|ensembl:ENSP00000453785 intact:EBI-718596|uniprotkb:Q502Y5|uniprotkb:Q9H0W0|uniprotkb:Q9NRP1|uniprotkb:Q6FIF8|uniprotkb:Q6IAH3|uniprotkb:Q9NRU7|ensembl:ENSP00000447058 psi-mi:snx1_human(display_long)|uniprotkb:SNX1(gene name)|psi-mi:SNX1(display_short) psi-mi:vps29_human(display_long)|uniprotkb:Vesicle protein sorting 29(gene name synonym)|uniprotkb:PEP11 homolog(gene name synonym)|uniprotkb:VPS29(gene name)|psi-mi:VPS29(display_short)|uniprotkb:DC7(orf name)|uniprotkb:DC15(orf name)|uniprotkb:MDS007(orf name) psi-mi:"MI:0071"(molecular sieving) Haft et al. (2000) pubmed:11102511|imex:IM-23304 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9843548|imex:IM-23304-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003090.2|refseq:NP_683758.1|refseq:NP_001229862.1|ensembl:ENSG00000028528(gene)|ensembl:ENST00000559844(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030904"(retromer complex)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0031623"(receptor internalization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0072673"(lamellipodium morphogenesis)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990460"(leptin receptor binding)|interpro:IPR001683(Phox-like)|interpro:IPR005329(Sorting nexin, N-terminal)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028660|interpro:IPR034901|mint:Q13596|rcsb pdb:2I4K|rcsb pdb:4FZS|interpro:IPR036871|dip:DIP-398N refseq:NP_057310.1|refseq:NP_476528.1|ensembl:ENSG00000111237(gene)|ensembl:ENST00000549578(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|rcsb pdb:1W24|rcsb pdb:2R17|rcsb pdb:5GTU|rcsb pdb:5OSH|rcsb pdb:5OSI|rcsb pdb:5WYH|rcsb pdb:7BLN|reactome:R-HSA-3238698|dip:DIP-29077N - - - figure legend:8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2014/10/10 2014/11/18 rogid:nFyxCtQ9gHndLbuCjBiwhyWE5do9606 rogid:xjo28jAH7expkdli0DENjzLXpjw9606 intact-crc:1DC429C78775A1DB|rigid:XDenssr43GvWcFAblqemlusGkwU false myc tag:n-n myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q13596 uniprotkb:Q96QK1 intact:EBI-2822329|uniprotkb:O60750|uniprotkb:A8K6T7|uniprotkb:A6NM19|uniprotkb:O60751|uniprotkb:H0Y2M5|uniprotkb:Q6ZRJ8|ensembl:ENSP00000453785 intact:EBI-1054634|uniprotkb:Q561W2|uniprotkb:Q9H016|uniprotkb:Q9H096|uniprotkb:Q9H4P3|uniprotkb:Q9H8J0|uniprotkb:Q9NRS7|uniprotkb:Q9NVG2|uniprotkb:Q9NX80|uniprotkb:Q9NZK2|ensembl:ENSP00000299138 psi-mi:snx1_human(display_long)|uniprotkb:SNX1(gene name)|psi-mi:SNX1(display_short) psi-mi:vps35_human(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:VPS35(gene name)|psi-mi:VPS35(display_short)|uniprotkb:MEM3(gene name synonym)|uniprotkb:TCCCTA00141(orf name) psi-mi:"MI:0071"(molecular sieving) Haft et al. (2000) pubmed:11102511|imex:IM-23304 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9843548|imex:IM-23304-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003090.2|refseq:NP_683758.1|refseq:NP_001229862.1|ensembl:ENSG00000028528(gene)|ensembl:ENST00000559844(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030904"(retromer complex)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0031623"(receptor internalization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0072673"(lamellipodium morphogenesis)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990460"(leptin receptor binding)|interpro:IPR001683(Phox-like)|interpro:IPR005329(Sorting nexin, N-terminal)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028660|interpro:IPR034901|mint:Q13596|rcsb pdb:2I4K|rcsb pdb:4FZS|interpro:IPR036871|dip:DIP-398N refseq:NP_060676.2|rcsb pdb:5F0J|rcsb pdb:5F0K|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|rcsb pdb:5OSH|rcsb pdb:5OSI|rcsb pdb:7BLN|rcsb pdb:7BLO|reactome:R-HSA-3238698|ensembl:ENSG00000069329(gene)|ensembl:ENST00000299138(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0097422"(tubular endosome)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|rcsb pdb:2R17|dip:DIP-29076N - - - figure legend:8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2014/10/10 2014/11/18 rogid:nFyxCtQ9gHndLbuCjBiwhyWE5do9606 rogid:EXkMduDQKNCdp876vGF5vna9t389606 intact-crc:1DC429C78775A1DB|rigid:XDenssr43GvWcFAblqemlusGkwU false myc tag:n-n myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9UBQ0 uniprotkb:Q96QK1 intact:EBI-718596|uniprotkb:Q502Y5|uniprotkb:Q9H0W0|uniprotkb:Q9NRP1|uniprotkb:Q6FIF8|uniprotkb:Q6IAH3|uniprotkb:Q9NRU7|ensembl:ENSP00000447058 intact:EBI-1054634|uniprotkb:Q561W2|uniprotkb:Q9H016|uniprotkb:Q9H096|uniprotkb:Q9H4P3|uniprotkb:Q9H8J0|uniprotkb:Q9NRS7|uniprotkb:Q9NVG2|uniprotkb:Q9NX80|uniprotkb:Q9NZK2|ensembl:ENSP00000299138 psi-mi:vps29_human(display_long)|uniprotkb:Vesicle protein sorting 29(gene name synonym)|uniprotkb:PEP11 homolog(gene name synonym)|uniprotkb:VPS29(gene name)|psi-mi:VPS29(display_short)|uniprotkb:DC7(orf name)|uniprotkb:DC15(orf name)|uniprotkb:MDS007(orf name) psi-mi:vps35_human(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:VPS35(gene name)|psi-mi:VPS35(display_short)|uniprotkb:MEM3(gene name synonym)|uniprotkb:TCCCTA00141(orf name) psi-mi:"MI:0071"(molecular sieving) Haft et al. (2000) pubmed:11102511|imex:IM-23304 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9915762|imex:IM-23304-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057310.1|refseq:NP_476528.1|ensembl:ENSG00000111237(gene)|ensembl:ENST00000549578(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|rcsb pdb:1W24|rcsb pdb:2R17|rcsb pdb:5GTU|rcsb pdb:5OSH|rcsb pdb:5OSI|rcsb pdb:5WYH|rcsb pdb:7BLN|reactome:R-HSA-3238698|dip:DIP-29077N refseq:NP_060676.2|rcsb pdb:5F0J|rcsb pdb:5F0K|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|rcsb pdb:5OSH|rcsb pdb:5OSI|rcsb pdb:7BLN|rcsb pdb:7BLO|reactome:R-HSA-3238698|ensembl:ENSG00000069329(gene)|ensembl:ENST00000299138(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0097422"(tubular endosome)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|rcsb pdb:2R17|dip:DIP-29076N - - - figure legend:7C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2014/10/10 2014/11/04 rogid:xjo28jAH7expkdli0DENjzLXpjw9606 rogid:EXkMduDQKNCdp876vGF5vna9t389606 intact-crc:DF2A1EC3065887B4|rigid:XcMJ9vXNg8cw6p4RDhWkuSvaKXc false myc tag:n-n myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:G3V8A5 uniprotkb:Q6AY86 intact:EBI-9843458|ensembl:ENSRNOP00000024020 intact:EBI-9843441|ensembl:ENSRNOP00000062170 psi-mi:g3v8a5_rat(display_long)|uniprotkb:Vps35(gene name)|psi-mi:Vps35(display_short)|uniprotkb:Vps35_mapped(gene name synonym)|uniprotkb:rCG_44281(orf name) psi-mi:vp26a_rat(display_long)|uniprotkb:Vps26a(gene name)|psi-mi:Vps26a(display_short)|uniprotkb:Vps26(gene name synonym)|uniprotkb:Vesicle protein sorting 26A(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Haft et al. (2000) pubmed:11102511|imex:IM-23304 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9843510|imex:IM-23304-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001099188.2|rgd:1589784|ensembl:ENSRNOG00000017612(gene)|ensembl:ENSRNOT00000024020(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007416"(synapse assembly)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032463"(negative regulation of protein homooligomerization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090326"(positive regulation of locomotion involved in locomotory behavior)|go:"GO:0097422"(tubular endosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903181"(positive regulation of dopamine biosynthetic process)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903828"(negative regulation of protein localization)|go:"GO:1905166"(negative regulation of lysosomal protein catabolic process)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|reactome:R-RNO-3238698 refseq:NP_001007741.1|rgd:1359254|ensembl:ENSRNOG00000030683(gene)|ensembl:ENSRNOT00000067883(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031982"(vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0097422"(tubular endosome)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR028934|reactome:R-RNO-3238698 - - - figure legend:5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2014/10/10 2014/10/16 rogid:9H/8n7q9kWa918SPxTMzp9xRek810116 rogid:Rawqvx7w912A1Mq74mEF2bONzdY10116 intact-crc:669D810D42A1B175|rigid:billM1aBnH3+xmEnjXT/qsFc0bk false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O60749 uniprotkb:Q13596 intact:EBI-1046690|uniprotkb:O43650|uniprotkb:P82862|uniprotkb:Q53XK8|uniprotkb:Q597H6|uniprotkb:Q9BTS8|ensembl:ENSP00000368831|uniprotkb:B3KN44|uniprotkb:B4DEK4|uniprotkb:B7Z408 intact:EBI-2822329|uniprotkb:O60750|uniprotkb:A8K6T7|uniprotkb:A6NM19|uniprotkb:O60751|uniprotkb:H0Y2M5|uniprotkb:Q6ZRJ8|ensembl:ENSP00000453785 psi-mi:snx2_human(display_long)|uniprotkb:Transformation-related gene 9 protein(gene name synonym)|uniprotkb:SNX2(gene name)|psi-mi:SNX2(display_short)|uniprotkb:TRG9(orf name) psi-mi:snx1_human(display_long)|uniprotkb:SNX1(gene name)|psi-mi:SNX1(display_short) psi-mi:"MI:0727"(lexa b52 complementation) Haft et al. (2000) pubmed:11102511|imex:IM-23304 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9843581|imex:IM-23304-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003091.2|ensembl:ENSG00000205302(gene)|ensembl:ENST00000379516(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030904"(retromer complex)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0072673"(lamellipodium morphogenesis)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990460"(leptin receptor binding)|interpro:IPR001683(Phox-like)|interpro:IPR005329(Sorting nexin, N-terminal)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028653|interpro:IPR037918|mint:O60749|interpro:IPR036871|reactome:R-HSA-432722|refseq:NP_001265128.1 refseq:NP_003090.2|refseq:NP_683758.1|refseq:NP_001229862.1|ensembl:ENSG00000028528(gene)|ensembl:ENST00000559844(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030904"(retromer complex)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0031623"(receptor internalization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0072673"(lamellipodium morphogenesis)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990460"(leptin receptor binding)|interpro:IPR001683(Phox-like)|interpro:IPR005329(Sorting nexin, N-terminal)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028660|interpro:IPR034901|mint:Q13596|rcsb pdb:2I4K|rcsb pdb:4FZS|interpro:IPR036871|dip:DIP-398N - - - figure legend:9|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/10/10 2014/10/16 rogid:Sb/i4ZNGqy+ixeexnp0/4uOo3jo9606 rogid:nFyxCtQ9gHndLbuCjBiwhyWE5do9606 intact-crc:944A94DE5DFF44C2|rigid:lRm6Ha7n8J1CwWMZC6f++r2oUSY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96QK1 uniprotkb:Q13596 intact:EBI-1054634|uniprotkb:Q561W2|uniprotkb:Q9H016|uniprotkb:Q9H096|uniprotkb:Q9H4P3|uniprotkb:Q9H8J0|uniprotkb:Q9NRS7|uniprotkb:Q9NVG2|uniprotkb:Q9NX80|uniprotkb:Q9NZK2|ensembl:ENSP00000299138 intact:EBI-2822329|uniprotkb:O60750|uniprotkb:A8K6T7|uniprotkb:A6NM19|uniprotkb:O60751|uniprotkb:H0Y2M5|uniprotkb:Q6ZRJ8|ensembl:ENSP00000453785 psi-mi:vps35_human(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:VPS35(gene name)|psi-mi:VPS35(display_short)|uniprotkb:MEM3(gene name synonym)|uniprotkb:TCCCTA00141(orf name) psi-mi:snx1_human(display_long)|uniprotkb:SNX1(gene name)|psi-mi:SNX1(display_short) psi-mi:"MI:0727"(lexa b52 complementation) Haft et al. (2000) pubmed:11102511|imex:IM-23304 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9843577|imex:IM-23304-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060676.2|rcsb pdb:5F0J|rcsb pdb:5F0K|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|rcsb pdb:5OSH|rcsb pdb:5OSI|rcsb pdb:7BLN|rcsb pdb:7BLO|reactome:R-HSA-3238698|ensembl:ENSG00000069329(gene)|ensembl:ENST00000299138(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0097422"(tubular endosome)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|rcsb pdb:2R17|dip:DIP-29076N refseq:NP_003090.2|refseq:NP_683758.1|refseq:NP_001229862.1|ensembl:ENSG00000028528(gene)|ensembl:ENST00000559844(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030904"(retromer complex)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0031623"(receptor internalization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0072673"(lamellipodium morphogenesis)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990460"(leptin receptor binding)|interpro:IPR001683(Phox-like)|interpro:IPR005329(Sorting nexin, N-terminal)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028660|interpro:IPR034901|mint:Q13596|rcsb pdb:2I4K|rcsb pdb:4FZS|interpro:IPR036871|dip:DIP-398N - - - figure legend:9 and 10C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/10/10 2014/11/04 rogid:EXkMduDQKNCdp876vGF5vna9t389606 rogid:nFyxCtQ9gHndLbuCjBiwhyWE5do9606 intact-crc:3814CBA12E60D463|rigid:NFLNH141gO9R2yOh1vqyWap38Bs false sufficient binding region:1-53|sufficient binding region:307-796 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q13596 uniprotkb:Q13596 intact:EBI-2822329|uniprotkb:O60750|uniprotkb:A8K6T7|uniprotkb:A6NM19|uniprotkb:O60751|uniprotkb:H0Y2M5|uniprotkb:Q6ZRJ8|ensembl:ENSP00000453785 intact:EBI-2822329|uniprotkb:O60750|uniprotkb:A8K6T7|uniprotkb:A6NM19|uniprotkb:O60751|uniprotkb:H0Y2M5|uniprotkb:Q6ZRJ8|ensembl:ENSP00000453785 psi-mi:snx1_human(display_long)|uniprotkb:SNX1(gene name)|psi-mi:SNX1(display_short) psi-mi:snx1_human(display_long)|uniprotkb:SNX1(gene name)|psi-mi:SNX1(display_short) psi-mi:"MI:0727"(lexa b52 complementation) Haft et al. (2000) pubmed:11102511|imex:IM-23304 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9843593|imex:IM-23304-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003090.2|refseq:NP_683758.1|refseq:NP_001229862.1|ensembl:ENSG00000028528(gene)|ensembl:ENST00000559844(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030904"(retromer complex)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0031623"(receptor internalization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0072673"(lamellipodium morphogenesis)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990460"(leptin receptor binding)|interpro:IPR001683(Phox-like)|interpro:IPR005329(Sorting nexin, N-terminal)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028660|interpro:IPR034901|mint:Q13596|rcsb pdb:2I4K|rcsb pdb:4FZS|interpro:IPR036871|dip:DIP-398N refseq:NP_003090.2|refseq:NP_683758.1|refseq:NP_001229862.1|ensembl:ENSG00000028528(gene)|ensembl:ENST00000559844(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030904"(retromer complex)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0031623"(receptor internalization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0072673"(lamellipodium morphogenesis)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990460"(leptin receptor binding)|interpro:IPR001683(Phox-like)|interpro:IPR005329(Sorting nexin, N-terminal)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028660|interpro:IPR034901|mint:Q13596|rcsb pdb:2I4K|rcsb pdb:4FZS|interpro:IPR036871|dip:DIP-398N - - - figure legend:9|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/10/10 2014/10/16 rogid:nFyxCtQ9gHndLbuCjBiwhyWE5do9606 rogid:nFyxCtQ9gHndLbuCjBiwhyWE5do9606 intact-crc:EEFECA6235EB6C9B|rigid:aSlmj9Nz09ywViPe1WkXCk8KrG0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O60749 uniprotkb:Q13596 intact:EBI-1046690|uniprotkb:O43650|uniprotkb:P82862|uniprotkb:Q53XK8|uniprotkb:Q597H6|uniprotkb:Q9BTS8|ensembl:ENSP00000368831|uniprotkb:B3KN44|uniprotkb:B4DEK4|uniprotkb:B7Z408 intact:EBI-2822329|uniprotkb:O60750|uniprotkb:A8K6T7|uniprotkb:A6NM19|uniprotkb:O60751|uniprotkb:H0Y2M5|uniprotkb:Q6ZRJ8|ensembl:ENSP00000453785 psi-mi:snx2_human(display_long)|uniprotkb:Transformation-related gene 9 protein(gene name synonym)|uniprotkb:SNX2(gene name)|psi-mi:SNX2(display_short)|uniprotkb:TRG9(orf name) psi-mi:snx1_human(display_long)|uniprotkb:SNX1(gene name)|psi-mi:SNX1(display_short) psi-mi:"MI:0727"(lexa b52 complementation) Haft et al. (2000) pubmed:11102511|imex:IM-23304 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9843585|imex:IM-23304-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003091.2|ensembl:ENSG00000205302(gene)|ensembl:ENST00000379516(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030904"(retromer complex)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0072673"(lamellipodium morphogenesis)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990460"(leptin receptor binding)|interpro:IPR001683(Phox-like)|interpro:IPR005329(Sorting nexin, N-terminal)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028653|interpro:IPR037918|mint:O60749|interpro:IPR036871|reactome:R-HSA-432722|refseq:NP_001265128.1 refseq:NP_003090.2|refseq:NP_683758.1|refseq:NP_001229862.1|ensembl:ENSG00000028528(gene)|ensembl:ENST00000559844(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030904"(retromer complex)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0031623"(receptor internalization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0072673"(lamellipodium morphogenesis)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990460"(leptin receptor binding)|interpro:IPR001683(Phox-like)|interpro:IPR005329(Sorting nexin, N-terminal)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028660|interpro:IPR034901|mint:Q13596|rcsb pdb:2I4K|rcsb pdb:4FZS|interpro:IPR036871|dip:DIP-398N - - - figure legend:9|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/10/10 2014/10/16 rogid:Sb/i4ZNGqy+ixeexnp0/4uOo3jo9606 rogid:nFyxCtQ9gHndLbuCjBiwhyWE5do9606 intact-crc:78C03D221DFF4374|rigid:lRm6Ha7n8J1CwWMZC6f++r2oUSY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96QK1 uniprotkb:O75436 intact:EBI-1054634|uniprotkb:Q561W2|uniprotkb:Q9H016|uniprotkb:Q9H096|uniprotkb:Q9H4P3|uniprotkb:Q9H8J0|uniprotkb:Q9NRS7|uniprotkb:Q9NVG2|uniprotkb:Q9NX80|uniprotkb:Q9NZK2|ensembl:ENSP00000299138 intact:EBI-1043891|uniprotkb:Q8TBH4|uniprotkb:Q9H982|ensembl:ENSP00000263559|ensembl:ENSP00000362480|uniprotkb:B2RDD3|uniprotkb:A8MZ56 psi-mi:vps35_human(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:VPS35(gene name)|psi-mi:VPS35(display_short)|uniprotkb:MEM3(gene name synonym)|uniprotkb:TCCCTA00141(orf name) psi-mi:vp26a_human(display_long)|uniprotkb:VPS26A(gene name)|psi-mi:VPS26A(display_short)|uniprotkb:VPS26(gene name synonym)|uniprotkb:Vesicle protein sorting 26A(gene name synonym) psi-mi:"MI:0727"(lexa b52 complementation) Haft et al. (2000) pubmed:11102511|imex:IM-23304 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9843569|imex:IM-23304-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060676.2|rcsb pdb:5F0J|rcsb pdb:5F0K|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|rcsb pdb:5OSH|rcsb pdb:5OSI|rcsb pdb:7BLN|rcsb pdb:7BLO|reactome:R-HSA-3238698|ensembl:ENSG00000069329(gene)|ensembl:ENST00000299138(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0097422"(tubular endosome)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|rcsb pdb:2R17|dip:DIP-29076N ensembl:ENSG00000122958(gene)|ensembl:ENST00000263559(transcript)|ensembl:ENST00000373382(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031982"(vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0097422"(tubular endosome)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR028934|mint:O75436|rcsb pdb:2FAU|rcsb pdb:5F0J|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|reactome:R-HSA-3238698|rcsb pdb:7BLO|refseq:NP_001030337.1|refseq:NP_004887.2|refseq:NP_001305875.1|dip:DIP-29075N - - - figure legend:9 and 10A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/10/10 2014/10/16 rogid:EXkMduDQKNCdp876vGF5vna9t389606 rogid:n0uOd+2HQmRW7koIy678uP0d3+o9606 intact-crc:595A92569A85FDB5|rigid:GyW9633bdSt0TW9Pfbxyxu1Qcoc false sufficient binding region:1-172|necessary binding region:122-172 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O60749 uniprotkb:O60749 intact:EBI-1046690|uniprotkb:O43650|uniprotkb:P82862|uniprotkb:Q53XK8|uniprotkb:Q597H6|uniprotkb:Q9BTS8|ensembl:ENSP00000368831|uniprotkb:B3KN44|uniprotkb:B4DEK4|uniprotkb:B7Z408 intact:EBI-1046690|uniprotkb:O43650|uniprotkb:P82862|uniprotkb:Q53XK8|uniprotkb:Q597H6|uniprotkb:Q9BTS8|ensembl:ENSP00000368831|uniprotkb:B3KN44|uniprotkb:B4DEK4|uniprotkb:B7Z408 psi-mi:snx2_human(display_long)|uniprotkb:Transformation-related gene 9 protein(gene name synonym)|uniprotkb:SNX2(gene name)|psi-mi:SNX2(display_short)|uniprotkb:TRG9(orf name) psi-mi:snx2_human(display_long)|uniprotkb:Transformation-related gene 9 protein(gene name synonym)|uniprotkb:SNX2(gene name)|psi-mi:SNX2(display_short)|uniprotkb:TRG9(orf name) psi-mi:"MI:0727"(lexa b52 complementation) Haft et al. (2000) pubmed:11102511|imex:IM-23304 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9843589|imex:IM-23304-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003091.2|ensembl:ENSG00000205302(gene)|ensembl:ENST00000379516(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030904"(retromer complex)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0072673"(lamellipodium morphogenesis)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990460"(leptin receptor binding)|interpro:IPR001683(Phox-like)|interpro:IPR005329(Sorting nexin, N-terminal)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028653|interpro:IPR037918|mint:O60749|interpro:IPR036871|reactome:R-HSA-432722|refseq:NP_001265128.1 refseq:NP_003091.2|ensembl:ENSG00000205302(gene)|ensembl:ENST00000379516(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030904"(retromer complex)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0072673"(lamellipodium morphogenesis)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990460"(leptin receptor binding)|interpro:IPR001683(Phox-like)|interpro:IPR005329(Sorting nexin, N-terminal)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028653|interpro:IPR037918|mint:O60749|interpro:IPR036871|reactome:R-HSA-432722|refseq:NP_001265128.1 - - - figure legend:9|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/10/10 2014/10/16 rogid:Sb/i4ZNGqy+ixeexnp0/4uOo3jo9606 rogid:Sb/i4ZNGqy+ixeexnp0/4uOo3jo9606 intact-crc:14FF679D51B3029B|rigid:d7RX4PmqGHmMcINiPOpPC2dEZ1M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96QK1 uniprotkb:Q9UBQ0 intact:EBI-1054634|uniprotkb:Q561W2|uniprotkb:Q9H016|uniprotkb:Q9H096|uniprotkb:Q9H4P3|uniprotkb:Q9H8J0|uniprotkb:Q9NRS7|uniprotkb:Q9NVG2|uniprotkb:Q9NX80|uniprotkb:Q9NZK2|ensembl:ENSP00000299138 intact:EBI-718596|uniprotkb:Q502Y5|uniprotkb:Q9H0W0|uniprotkb:Q9NRP1|uniprotkb:Q6FIF8|uniprotkb:Q6IAH3|uniprotkb:Q9NRU7|ensembl:ENSP00000447058 psi-mi:vps35_human(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:VPS35(gene name)|psi-mi:VPS35(display_short)|uniprotkb:MEM3(gene name synonym)|uniprotkb:TCCCTA00141(orf name) psi-mi:vps29_human(display_long)|uniprotkb:Vesicle protein sorting 29(gene name synonym)|uniprotkb:PEP11 homolog(gene name synonym)|uniprotkb:VPS29(gene name)|psi-mi:VPS29(display_short)|uniprotkb:DC7(orf name)|uniprotkb:DC15(orf name)|uniprotkb:MDS007(orf name) psi-mi:"MI:0727"(lexa b52 complementation) Haft et al. (2000) pubmed:11102511|imex:IM-23304 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9843573|imex:IM-23304-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060676.2|rcsb pdb:5F0J|rcsb pdb:5F0K|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|rcsb pdb:5OSH|rcsb pdb:5OSI|rcsb pdb:7BLN|rcsb pdb:7BLO|reactome:R-HSA-3238698|ensembl:ENSG00000069329(gene)|ensembl:ENST00000299138(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0097422"(tubular endosome)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|rcsb pdb:2R17|dip:DIP-29076N refseq:NP_057310.1|refseq:NP_476528.1|ensembl:ENSG00000111237(gene)|ensembl:ENST00000549578(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|rcsb pdb:1W24|rcsb pdb:2R17|rcsb pdb:5GTU|rcsb pdb:5OSH|rcsb pdb:5OSI|rcsb pdb:5WYH|rcsb pdb:7BLN|reactome:R-HSA-3238698|dip:DIP-29077N - - - figure legend:9and 10B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/10/10 2014/10/16 rogid:EXkMduDQKNCdp876vGF5vna9t389606 rogid:xjo28jAH7expkdli0DENjzLXpjw9606 intact-crc:79FC09B76B675A5A|rigid:XcMJ9vXNg8cw6p4RDhWkuSvaKXc false sufficient binding region:307-796 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-9843622 intact:EBI-9843626 - - psi-mi:chlae-snx2(display_short)|psi-mi:EBI-9843622(display_long) psi-mi:chlae-vps26a(display_short)|psi-mi:EBI-9843626(display_long) psi-mi:"MI:0071"(molecular sieving) Haft et al. (2000) pubmed:11102511|imex:IM-23304 taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9843631|imex:IM-23304-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - - go:"GO:0005829"(cytosol) comment:"Similar to human SNX2 UniProt AC: O60749" comment:"similar ti human VPS26A UniProt AC: O75436" figure legend:6A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2014/10/10 2014/11/03 - - intact-crc:5F5ECC01D37EF464 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) intact:EBI-9843622 intact:EBI-9843628 - - psi-mi:chlae-snx2(display_short)|psi-mi:EBI-9843622(display_long) psi-mi:chlae-vps29(display_short)|psi-mi:EBI-9843628(display_long) psi-mi:"MI:0071"(molecular sieving) Haft et al. (2000) pubmed:11102511|imex:IM-23304 taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9843631|imex:IM-23304-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - - go:"GO:0005829"(cytosol) comment:"Similar to human SNX2 UniProt AC: O60749" comment:"Similar to human VPS29 UniProt AC: Q9UBQ0" figure legend:6A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2014/10/10 2014/11/03 - - intact-crc:5F5ECC01D37EF464 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) intact:EBI-9843622 intact:EBI-9843620 - - psi-mi:chlae-snx2(display_short)|psi-mi:EBI-9843622(display_long) psi-mi:chlae-vps35(display_short)|psi-mi:EBI-9843620(display_long) psi-mi:"MI:0071"(molecular sieving) Haft et al. (2000) pubmed:11102511|imex:IM-23304 taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9843631|imex:IM-23304-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - - go:"GO:0005829"(cytosol) comment:"Similar to human SNX2 UniProt AC: O60749" comment:"Similar to human VPS35 UniProt AC: Q96QK1" figure legend:6A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2014/10/10 2014/11/03 - - intact-crc:5F5ECC01D37EF464 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)