#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O60762 uniprotkb:O94777 intact:EBI-719526|uniprotkb:O15157|uniprotkb:Q96HK0|uniprotkb:Q6IB78|ensembl:ENSP00000360644 intact:EBI-9097061|uniprotkb:Q5XKK9|uniprotkb:Q6FGH3|ensembl:ENSP00000322181 psi-mi:dpm1_human(display_long)|uniprotkb:DPM1(gene name)|psi-mi:DPM1(display_short)|uniprotkb:Dolichol-phosphate mannose synthase subunit 1(gene name synonym)|uniprotkb:Dolichyl-phosphate beta-D-mannosyltransferase subunit 1(gene name synonym)|uniprotkb:Mannose-P-dolichol synthase subunit 1(gene name synonym) psi-mi:dpm2_human(display_long)|uniprotkb:DPM2(gene name)|psi-mi:DPM2(display_short)|uniprotkb:Dolichol-phosphate mannose synthase subunit 2(gene name synonym)|uniprotkb:My026(orf name) psi-mi:"MI:0676"(tandem affinity purification) Maeda et al. (2000) pubmed:10835346|imex:IM-22040 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-9097112|imex:IM-22040-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003850.1|refseq:NP_001303963.1|refseq:NP_001303964.1|refseq:NP_001303965.1|ensembl:ENSG00000000419(gene)|ensembl:ENST00000371588(transcript)|go:"GO:0004169"(dolichyl-phosphate-mannose-protein mannosyltransferase activity)|go:"GO:0004582"(dolichyl-phosphate beta-D-mannosyltransferase activity)|go:"GO:0005537"(mannose binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0019348"(dolichol metabolic process)|go:"GO:0019673"(GDP-mannose metabolic process)|go:"GO:0033185"(dolichol-phosphate-mannose synthase complex)|go:"GO:0035268"(protein mannosylation)|go:"GO:0035269"(protein O-linked mannosylation)|go:"GO:0043178"(alcohol binding)|interpro:IPR001173(Glycosyl transferase, family 2)|interpro:IPR029044|interpro:IPR039528|mint:O60762|reactome:R-HSA-162699|reactome:R-HSA-4717374|reactome:R-HSA-4719360|reactome:R-HSA-4719377 refseq:NP_003854.1|ensembl:ENSG00000136908(gene)|ensembl:ENST00000314392(transcript)|go:"GO:0000506"("glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex")|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0019348"(dolichol metabolic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033185"(dolichol-phosphate-mannose synthase complex)|go:"GO:0035269"(protein O-linked mannosylation)|interpro:IPR009914(Dolichol phosphate-mannose biosynthesis regulatory)|reactome:R-HSA-162699|reactome:R-HSA-162710|reactome:R-HSA-4717374|reactome:R-HSA-4719360|reactome:R-HSA-4719377 - - - figure legend:1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-jy25)|taxid:9606(Homo sapiens B--lymphoblastoid JY25 cells) - 2014/01/23 2021/03/09 rogid:znbNDwp7t238ByanlbQzsTMvwTY9606 rogid:b1kR+UX6Sfr1TcOpQ0D4M3+xy8M9606 intact-crc:86901B3E732CEF8F|rigid:NZLBHmAx2hIX/Pw+lEdUUJAo1IE false flag tag:?-?|glutathione s tranferase tag:?-? - - - psi-mi:"MI:0433"(partial identification of protein sequence) psi-mi:"MI:0433"(partial identification of protein sequence) uniprotkb:O60762 uniprotkb:Q9P2X0 intact:EBI-719526|uniprotkb:O15157|uniprotkb:Q96HK0|uniprotkb:Q6IB78|ensembl:ENSP00000360644 intact:EBI-9087337|uniprotkb:Q5SR62|uniprotkb:Q5SR63|uniprotkb:Q9BXN4|uniprotkb:Q9BXN5|ensembl:ENSP00000344338|ensembl:ENSP00000357385 psi-mi:dpm1_human(display_long)|uniprotkb:DPM1(gene name)|psi-mi:DPM1(display_short)|uniprotkb:Dolichol-phosphate mannose synthase subunit 1(gene name synonym)|uniprotkb:Dolichyl-phosphate beta-D-mannosyltransferase subunit 1(gene name synonym)|uniprotkb:Mannose-P-dolichol synthase subunit 1(gene name synonym) psi-mi:dpm3_human(display_long)|uniprotkb:DPM3(gene name)|psi-mi:DPM3(display_short)|uniprotkb:Dolichol-phosphate mannose synthase subunit 3(gene name synonym)|uniprotkb:Dolichyl-phosphate beta-D-mannosyltransferase subunit 3(gene name synonym)|uniprotkb:Mannose-P-dolichol synthase subunit 3(gene name synonym)|uniprotkb:Prostin-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Maeda et al. (2000) pubmed:10835346|imex:IM-22040 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-9097112|imex:IM-22040-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003850.1|refseq:NP_001303963.1|refseq:NP_001303964.1|refseq:NP_001303965.1|ensembl:ENSG00000000419(gene)|ensembl:ENST00000371588(transcript)|go:"GO:0004169"(dolichyl-phosphate-mannose-protein mannosyltransferase activity)|go:"GO:0004582"(dolichyl-phosphate beta-D-mannosyltransferase activity)|go:"GO:0005537"(mannose binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0019348"(dolichol metabolic process)|go:"GO:0019673"(GDP-mannose metabolic process)|go:"GO:0033185"(dolichol-phosphate-mannose synthase complex)|go:"GO:0035268"(protein mannosylation)|go:"GO:0035269"(protein O-linked mannosylation)|go:"GO:0043178"(alcohol binding)|interpro:IPR001173(Glycosyl transferase, family 2)|interpro:IPR029044|interpro:IPR039528|mint:O60762|reactome:R-HSA-162699|reactome:R-HSA-4717374|reactome:R-HSA-4719360|reactome:R-HSA-4719377 refseq:XP_016856987.1|refseq:NP_061846.2|refseq:NP_714963.1|ensembl:ENSG00000179085(gene)|ensembl:ENST00000341298(transcript)|ensembl:ENST00000368400(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0018406"(protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031501"(mannosyltransferase complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033185"(dolichol-phosphate-mannose synthase complex)|go:"GO:0035268"(protein mannosylation)|go:"GO:0035269"(protein O-linked mannosylation)|interpro:IPR013174(Dolichol-phosphate mannosyltransferase subunit 3)|reactome:R-HSA-162699|reactome:R-HSA-4717374|reactome:R-HSA-4719360|reactome:R-HSA-4719377 - - - figure legend:1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-jy25)|taxid:9606(Homo sapiens B--lymphoblastoid JY25 cells) - 2014/01/23 2021/03/09 rogid:znbNDwp7t238ByanlbQzsTMvwTY9606 rogid:0wf0wox4cCMWDiy9qDpf2l7NTps9606 intact-crc:86901B3E732CEF8F|rigid:NZLBHmAx2hIX/Pw+lEdUUJAo1IE false flag tag:?-?|glutathione s tranferase tag:?-? - - - psi-mi:"MI:0433"(partial identification of protein sequence) psi-mi:"MI:0433"(partial identification of protein sequence) uniprotkb:O60762 uniprotkb:Q9P2X0 intact:EBI-719526|uniprotkb:O15157|uniprotkb:Q96HK0|uniprotkb:Q6IB78|ensembl:ENSP00000360644 intact:EBI-9087337|uniprotkb:Q5SR62|uniprotkb:Q5SR63|uniprotkb:Q9BXN4|uniprotkb:Q9BXN5|ensembl:ENSP00000344338|ensembl:ENSP00000357385 psi-mi:dpm1_human(display_long)|uniprotkb:DPM1(gene name)|psi-mi:DPM1(display_short)|uniprotkb:Dolichol-phosphate mannose synthase subunit 1(gene name synonym)|uniprotkb:Dolichyl-phosphate beta-D-mannosyltransferase subunit 1(gene name synonym)|uniprotkb:Mannose-P-dolichol synthase subunit 1(gene name synonym) psi-mi:dpm3_human(display_long)|uniprotkb:DPM3(gene name)|psi-mi:DPM3(display_short)|uniprotkb:Dolichol-phosphate mannose synthase subunit 3(gene name synonym)|uniprotkb:Dolichyl-phosphate beta-D-mannosyltransferase subunit 3(gene name synonym)|uniprotkb:Mannose-P-dolichol synthase subunit 3(gene name synonym)|uniprotkb:Prostin-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Maeda et al. (2000) pubmed:10835346|imex:IM-22040 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-9097087|imex:IM-22040-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003850.1|refseq:NP_001303963.1|refseq:NP_001303964.1|refseq:NP_001303965.1|ensembl:ENSG00000000419(gene)|ensembl:ENST00000371588(transcript)|go:"GO:0004169"(dolichyl-phosphate-mannose-protein mannosyltransferase activity)|go:"GO:0004582"(dolichyl-phosphate beta-D-mannosyltransferase activity)|go:"GO:0005537"(mannose binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0019348"(dolichol metabolic process)|go:"GO:0019673"(GDP-mannose metabolic process)|go:"GO:0033185"(dolichol-phosphate-mannose synthase complex)|go:"GO:0035268"(protein mannosylation)|go:"GO:0035269"(protein O-linked mannosylation)|go:"GO:0043178"(alcohol binding)|interpro:IPR001173(Glycosyl transferase, family 2)|interpro:IPR029044|interpro:IPR039528|mint:O60762|reactome:R-HSA-162699|reactome:R-HSA-4717374|reactome:R-HSA-4719360|reactome:R-HSA-4719377 refseq:XP_016856987.1|refseq:NP_061846.2|refseq:NP_714963.1|ensembl:ENSG00000179085(gene)|ensembl:ENST00000341298(transcript)|ensembl:ENST00000368400(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0018406"(protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031501"(mannosyltransferase complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033185"(dolichol-phosphate-mannose synthase complex)|go:"GO:0035268"(protein mannosylation)|go:"GO:0035269"(protein O-linked mannosylation)|interpro:IPR013174(Dolichol-phosphate mannosyltransferase subunit 3)|reactome:R-HSA-162699|reactome:R-HSA-4717374|reactome:R-HSA-4719360|reactome:R-HSA-4719377 go:"GO:0033185"(dolichol-phosphate-mannose synthase complex)|go:"GO:0004169"(dolichyl-phosphate-mannose-protein mannosyltransferase activity) - - figure legend:1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-jy25)|taxid:9606(Homo sapiens B--lymphoblastoid JY25 cells) - 2014/01/23 2021/03/09 rogid:znbNDwp7t238ByanlbQzsTMvwTY9606 rogid:0wf0wox4cCMWDiy9qDpf2l7NTps9606 intact-crc:41D023683B8D5DD7|rigid:NZLBHmAx2hIX/Pw+lEdUUJAo1IE false glutathione s tranferase tag:?-?|flag tag:?-? - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:O60762 uniprotkb:O94777 intact:EBI-719526|uniprotkb:O15157|uniprotkb:Q96HK0|uniprotkb:Q6IB78|ensembl:ENSP00000360644 intact:EBI-9097061|uniprotkb:Q5XKK9|uniprotkb:Q6FGH3|ensembl:ENSP00000322181 psi-mi:dpm1_human(display_long)|uniprotkb:DPM1(gene name)|psi-mi:DPM1(display_short)|uniprotkb:Dolichol-phosphate mannose synthase subunit 1(gene name synonym)|uniprotkb:Dolichyl-phosphate beta-D-mannosyltransferase subunit 1(gene name synonym)|uniprotkb:Mannose-P-dolichol synthase subunit 1(gene name synonym) psi-mi:dpm2_human(display_long)|uniprotkb:DPM2(gene name)|psi-mi:DPM2(display_short)|uniprotkb:Dolichol-phosphate mannose synthase subunit 2(gene name synonym)|uniprotkb:My026(orf name) psi-mi:"MI:0676"(tandem affinity purification) Maeda et al. (2000) pubmed:10835346|imex:IM-22040 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-9097087|imex:IM-22040-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003850.1|refseq:NP_001303963.1|refseq:NP_001303964.1|refseq:NP_001303965.1|ensembl:ENSG00000000419(gene)|ensembl:ENST00000371588(transcript)|go:"GO:0004169"(dolichyl-phosphate-mannose-protein mannosyltransferase activity)|go:"GO:0004582"(dolichyl-phosphate beta-D-mannosyltransferase activity)|go:"GO:0005537"(mannose binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0019348"(dolichol metabolic process)|go:"GO:0019673"(GDP-mannose metabolic process)|go:"GO:0033185"(dolichol-phosphate-mannose synthase complex)|go:"GO:0035268"(protein mannosylation)|go:"GO:0035269"(protein O-linked mannosylation)|go:"GO:0043178"(alcohol binding)|interpro:IPR001173(Glycosyl transferase, family 2)|interpro:IPR029044|interpro:IPR039528|mint:O60762|reactome:R-HSA-162699|reactome:R-HSA-4717374|reactome:R-HSA-4719360|reactome:R-HSA-4719377 refseq:NP_003854.1|ensembl:ENSG00000136908(gene)|ensembl:ENST00000314392(transcript)|go:"GO:0000506"("glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex")|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0019348"(dolichol metabolic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033185"(dolichol-phosphate-mannose synthase complex)|go:"GO:0035269"(protein O-linked mannosylation)|interpro:IPR009914(Dolichol phosphate-mannose biosynthesis regulatory)|reactome:R-HSA-162699|reactome:R-HSA-162710|reactome:R-HSA-4717374|reactome:R-HSA-4719360|reactome:R-HSA-4719377 go:"GO:0033185"(dolichol-phosphate-mannose synthase complex)|go:"GO:0004169"(dolichyl-phosphate-mannose-protein mannosyltransferase activity) - - figure legend:1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-jy25)|taxid:9606(Homo sapiens B--lymphoblastoid JY25 cells) - 2014/01/23 2021/03/09 rogid:znbNDwp7t238ByanlbQzsTMvwTY9606 rogid:b1kR+UX6Sfr1TcOpQ0D4M3+xy8M9606 intact-crc:41D023683B8D5DD7|rigid:NZLBHmAx2hIX/Pw+lEdUUJAo1IE false glutathione s tranferase tag:?-?|flag tag:?-? - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:Q9Z325 uniprotkb:Q9P2X0 intact:EBI-9097185 intact:EBI-9087337|uniprotkb:Q5SR62|uniprotkb:Q5SR63|uniprotkb:Q9BXN4|uniprotkb:Q9BXN5|ensembl:ENSP00000344338|ensembl:ENSP00000357385 psi-mi:dpm2_rat(display_long)|uniprotkb:Dpm2(gene name)|psi-mi:Dpm2(display_short)|uniprotkb:Dolichol-phosphate mannose synthase subunit 2(gene name synonym) psi-mi:dpm3_human(display_long)|uniprotkb:DPM3(gene name)|psi-mi:DPM3(display_short)|uniprotkb:Dolichol-phosphate mannose synthase subunit 3(gene name synonym)|uniprotkb:Dolichyl-phosphate beta-D-mannosyltransferase subunit 3(gene name synonym)|uniprotkb:Mannose-P-dolichol synthase subunit 3(gene name synonym)|uniprotkb:Prostin-1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Maeda et al. (2000) pubmed:10835346|imex:IM-22040 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9097230|imex:IM-22040-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-RNO-162699|reactome:R-RNO-162710|refseq:NP_062125.1|interpro:IPR009914(Dolichol phosphate-mannose biosynthesis regulatory)|rgd:2514|go:"GO:0000506"("glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex")|go:"GO:0004582"(dolichyl-phosphate beta-D-mannosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0019348"(dolichol metabolic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033185"(dolichol-phosphate-mannose synthase complex)|go:"GO:0048471"(perinuclear region of cytoplasm) refseq:XP_016856987.1|refseq:NP_061846.2|refseq:NP_714963.1|ensembl:ENSG00000179085(gene)|ensembl:ENST00000341298(transcript)|ensembl:ENST00000368400(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0018406"(protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031501"(mannosyltransferase complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033185"(dolichol-phosphate-mannose synthase complex)|go:"GO:0035268"(protein mannosylation)|go:"GO:0035269"(protein O-linked mannosylation)|interpro:IPR013174(Dolichol-phosphate mannosyltransferase subunit 3)|reactome:R-HSA-162699|reactome:R-HSA-4717374|reactome:R-HSA-4719360|reactome:R-HSA-4719377 - - - figure legend:4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_lec15)|taxid:10029(Cricetulus griseus CHO-derived Lec15 mutant cells defective in DPM synthesis) - 2014/01/23 2014/10/16 rogid:becCDzNy99TP180GcfPxVzOpvsE10116 rogid:0wf0wox4cCMWDiy9qDpf2l7NTps9606 intact-crc:ED6F77F65A3739E4|rigid:l7RYtItmB1Q/dUKh5eETpiYrAc0 false flag tag:n-n|mutation decreasing interaction:23-23,21-21 - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9Z325 uniprotkb:Q9P2X0 intact:EBI-9097185 intact:EBI-9087337|uniprotkb:Q5SR62|uniprotkb:Q5SR63|uniprotkb:Q9BXN4|uniprotkb:Q9BXN5|ensembl:ENSP00000344338|ensembl:ENSP00000357385 psi-mi:dpm2_rat(display_long)|uniprotkb:Dpm2(gene name)|psi-mi:Dpm2(display_short)|uniprotkb:Dolichol-phosphate mannose synthase subunit 2(gene name synonym) psi-mi:dpm3_human(display_long)|uniprotkb:DPM3(gene name)|psi-mi:DPM3(display_short)|uniprotkb:Dolichol-phosphate mannose synthase subunit 3(gene name synonym)|uniprotkb:Dolichyl-phosphate beta-D-mannosyltransferase subunit 3(gene name synonym)|uniprotkb:Mannose-P-dolichol synthase subunit 3(gene name synonym)|uniprotkb:Prostin-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Maeda et al. (2000) pubmed:10835346|imex:IM-22040 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9097182|imex:IM-22040-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-RNO-162699|reactome:R-RNO-162710|refseq:NP_062125.1|interpro:IPR009914(Dolichol phosphate-mannose biosynthesis regulatory)|rgd:2514|go:"GO:0000506"("glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex")|go:"GO:0004582"(dolichyl-phosphate beta-D-mannosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0019348"(dolichol metabolic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033185"(dolichol-phosphate-mannose synthase complex)|go:"GO:0048471"(perinuclear region of cytoplasm) refseq:XP_016856987.1|refseq:NP_061846.2|refseq:NP_714963.1|ensembl:ENSG00000179085(gene)|ensembl:ENST00000341298(transcript)|ensembl:ENST00000368400(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0018406"(protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031501"(mannosyltransferase complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033185"(dolichol-phosphate-mannose synthase complex)|go:"GO:0035268"(protein mannosylation)|go:"GO:0035269"(protein O-linked mannosylation)|interpro:IPR013174(Dolichol-phosphate mannosyltransferase subunit 3)|reactome:R-HSA-162699|reactome:R-HSA-4717374|reactome:R-HSA-4719360|reactome:R-HSA-4719377 - - - figure legend:4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_lec15)|taxid:10029(Cricetulus griseus CHO-derived Lec15 mutant cells defective in DPM synthesis) - 2014/01/23 2014/10/16 rogid:becCDzNy99TP180GcfPxVzOpvsE10116 rogid:0wf0wox4cCMWDiy9qDpf2l7NTps9606 intact-crc:668C3DACC5FA24C8|rigid:l7RYtItmB1Q/dUKh5eETpiYrAc0 false flag tag:n-n|mutation decreasing interaction:23-23,21-21 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O60762 uniprotkb:Q9P2X0 intact:EBI-719526|uniprotkb:O15157|uniprotkb:Q96HK0|uniprotkb:Q6IB78|ensembl:ENSP00000360644 intact:EBI-9087337|uniprotkb:Q5SR62|uniprotkb:Q5SR63|uniprotkb:Q9BXN4|uniprotkb:Q9BXN5|ensembl:ENSP00000344338|ensembl:ENSP00000357385 psi-mi:dpm1_human(display_long)|uniprotkb:DPM1(gene name)|psi-mi:DPM1(display_short)|uniprotkb:Dolichol-phosphate mannose synthase subunit 1(gene name synonym)|uniprotkb:Dolichyl-phosphate beta-D-mannosyltransferase subunit 1(gene name synonym)|uniprotkb:Mannose-P-dolichol synthase subunit 1(gene name synonym) psi-mi:dpm3_human(display_long)|uniprotkb:DPM3(gene name)|psi-mi:DPM3(display_short)|uniprotkb:Dolichol-phosphate mannose synthase subunit 3(gene name synonym)|uniprotkb:Dolichyl-phosphate beta-D-mannosyltransferase subunit 3(gene name synonym)|uniprotkb:Mannose-P-dolichol synthase subunit 3(gene name synonym)|uniprotkb:Prostin-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Maeda et al. (2000) pubmed:10835346|imex:IM-22040 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9097176|imex:IM-22040-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003850.1|refseq:NP_001303963.1|refseq:NP_001303964.1|refseq:NP_001303965.1|ensembl:ENSG00000000419(gene)|ensembl:ENST00000371588(transcript)|go:"GO:0004169"(dolichyl-phosphate-mannose-protein mannosyltransferase activity)|go:"GO:0004582"(dolichyl-phosphate beta-D-mannosyltransferase activity)|go:"GO:0005537"(mannose binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0019348"(dolichol metabolic process)|go:"GO:0019673"(GDP-mannose metabolic process)|go:"GO:0033185"(dolichol-phosphate-mannose synthase complex)|go:"GO:0035268"(protein mannosylation)|go:"GO:0035269"(protein O-linked mannosylation)|go:"GO:0043178"(alcohol binding)|interpro:IPR001173(Glycosyl transferase, family 2)|interpro:IPR029044|interpro:IPR039528|mint:O60762|reactome:R-HSA-162699|reactome:R-HSA-4717374|reactome:R-HSA-4719360|reactome:R-HSA-4719377 refseq:XP_016856987.1|refseq:NP_061846.2|refseq:NP_714963.1|ensembl:ENSG00000179085(gene)|ensembl:ENST00000341298(transcript)|ensembl:ENST00000368400(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0018406"(protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031501"(mannosyltransferase complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033185"(dolichol-phosphate-mannose synthase complex)|go:"GO:0035268"(protein mannosylation)|go:"GO:0035269"(protein O-linked mannosylation)|interpro:IPR013174(Dolichol-phosphate mannosyltransferase subunit 3)|reactome:R-HSA-162699|reactome:R-HSA-4717374|reactome:R-HSA-4719360|reactome:R-HSA-4719377 - - - figure legend:4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_lec15)|taxid:10029(Cricetulus griseus CHO-derived Lec15 mutant cells defective in DPM synthesis) - 2014/01/23 2014/10/16 rogid:znbNDwp7t238ByanlbQzsTMvwTY9606 rogid:0wf0wox4cCMWDiy9qDpf2l7NTps9606 intact-crc:700DF8B86CF6F0AA|rigid:gIZfToc36A0Y9+zRHcAdNqt4tgE false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O94777 uniprotkb:Q9P2X0 intact:EBI-9097061|uniprotkb:Q5XKK9|uniprotkb:Q6FGH3|ensembl:ENSP00000322181 intact:EBI-9087337|uniprotkb:Q5SR62|uniprotkb:Q5SR63|uniprotkb:Q9BXN4|uniprotkb:Q9BXN5|ensembl:ENSP00000344338|ensembl:ENSP00000357385 psi-mi:dpm2_human(display_long)|uniprotkb:DPM2(gene name)|psi-mi:DPM2(display_short)|uniprotkb:Dolichol-phosphate mannose synthase subunit 2(gene name synonym)|uniprotkb:My026(orf name) psi-mi:dpm3_human(display_long)|uniprotkb:DPM3(gene name)|psi-mi:DPM3(display_short)|uniprotkb:Dolichol-phosphate mannose synthase subunit 3(gene name synonym)|uniprotkb:Dolichyl-phosphate beta-D-mannosyltransferase subunit 3(gene name synonym)|uniprotkb:Mannose-P-dolichol synthase subunit 3(gene name synonym)|uniprotkb:Prostin-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Maeda et al. (2000) pubmed:10835346|imex:IM-22040 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9097247|imex:IM-22040-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003854.1|ensembl:ENSG00000136908(gene)|ensembl:ENST00000314392(transcript)|go:"GO:0000506"("glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex")|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0019348"(dolichol metabolic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033185"(dolichol-phosphate-mannose synthase complex)|go:"GO:0035269"(protein O-linked mannosylation)|interpro:IPR009914(Dolichol phosphate-mannose biosynthesis regulatory)|reactome:R-HSA-162699|reactome:R-HSA-162710|reactome:R-HSA-4717374|reactome:R-HSA-4719360|reactome:R-HSA-4719377 refseq:XP_016856987.1|refseq:NP_061846.2|refseq:NP_714963.1|ensembl:ENSG00000179085(gene)|ensembl:ENST00000341298(transcript)|ensembl:ENST00000368400(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0018406"(protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031501"(mannosyltransferase complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033185"(dolichol-phosphate-mannose synthase complex)|go:"GO:0035268"(protein mannosylation)|go:"GO:0035269"(protein O-linked mannosylation)|interpro:IPR013174(Dolichol-phosphate mannosyltransferase subunit 3)|reactome:R-HSA-162699|reactome:R-HSA-4717374|reactome:R-HSA-4719360|reactome:R-HSA-4719377 - - - figure legend:4C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_lec15)|taxid:10029(Cricetulus griseus CHO-derived Lec15 mutant cells defective in DPM synthesis) - 2014/01/23 2014/10/16 rogid:b1kR+UX6Sfr1TcOpQ0D4M3+xy8M9606 rogid:0wf0wox4cCMWDiy9qDpf2l7NTps9606 intact-crc:8BBB177BF6A10068|rigid:7s8qdN9+gzcyHMg6Sq3bM6pEZgI false glutathione s tranferase tag:n-n flag tag:n-n|sufficient binding region:1-65 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)