#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B ensembl:ENSG00000102081 uniprotkb:Q9UFW8 intact:EBI-9637067 intact:EBI-723153|uniprotkb:O15183|ensembl:ENSP00000381428|ensembl:ENSP00000381429|ensembl:ENSP00000418769|ensembl:ENSP00000420374|ensembl:ENSP00000502581|uniprotkb:D3DU38 uniprotkb:FMR1(gene name)|psi-mi:FMR1(display_short)|ensembl:fmr1_human_gene(shortlabel)|psi-mi:ENSG00000102081(display_long) psi-mi:cgbp1_human(display_long)|uniprotkb:p20-CGGBP DNA-binding protein(gene name synonym)|uniprotkb:20 kDa CGG-binding protein(gene name synonym)|uniprotkb:CGGBP1(gene name)|psi-mi:CGGBP1(display_short)|uniprotkb:CGGBP(gene name synonym) psi-mi:"MI:0412"(electrophoretic mobility supershift assay) Müller-Hartmann et al. (2000) pubmed:10692448 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1264"(NTNU) intact:EBI-9637060 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_001008391.1|refseq:NP_001182237.1|refseq:NP_003654.3|ensembl:ENSG00000163320(gene)|ensembl:ENST00000309534(transcript)|ensembl:ENST00000398392(transcript)|ensembl:ENST00000462901(transcript)|ensembl:ENST00000482016(transcript)|ensembl:ENST00000675130(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042802"(identical protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR033375|mint:Q9UFW8|refseq:XP_016862844.1 go:"GO:0003690"(double-stranded DNA binding) - comment:"'endogeneous' CGGBP1 in human-hela was assayed (native human-hela nuclear extracts)" figure legend:Fig 5D|causality statement:Q9UFW8 decreases expression at RNA level of ENSG00000102081|comment:"the DNA-probe used in the emsa interaction detection (rna28s) contains the same 5′-(CGG)n-3′ repeats as those found in the FMR1 region assayed in the reporter gene assay (see causality statement)"|comment:"CGGBP1 (Q9UFW8) decreases expression at mRNA level of FMR1 (ENSG00000102081) as ascertained by reporter gene assay in human-hela upon CGGBP1 overexpression"|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2014/05/22 2014/10/16 - rogid:1sg3JQWhmEQX9snN5SG1OjdRP1A9606 intact-crc:4561B9AD14697461 false 32p radiolabel:?-?|sufficient binding region:?-? - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) intact:EBI-9538855 uniprotkb:Q9UFW8 - intact:EBI-723153|uniprotkb:O15183|ensembl:ENSP00000381428|ensembl:ENSP00000381429|ensembl:ENSP00000418769|ensembl:ENSP00000420374|ensembl:ENSP00000502581|uniprotkb:D3DU38 psi-mi:rna28s_gene_probe(display_short)|psi-mi:EBI-9538855(display_long) psi-mi:cgbp1_human(display_long)|uniprotkb:p20-CGGBP DNA-binding protein(gene name synonym)|uniprotkb:20 kDa CGG-binding protein(gene name synonym)|uniprotkb:CGGBP1(gene name)|psi-mi:CGGBP1(display_short)|uniprotkb:CGGBP(gene name synonym) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Müller-Hartmann et al. (2000) pubmed:10692448 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1264"(NTNU) intact:EBI-9538851 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0681"(double stranded deoxyribonucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_001008391.1|refseq:NP_001182237.1|refseq:NP_003654.3|ensembl:ENSG00000163320(gene)|ensembl:ENST00000309534(transcript)|ensembl:ENST00000398392(transcript)|ensembl:ENST00000462901(transcript)|ensembl:ENST00000482016(transcript)|ensembl:ENST00000675130(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042802"(identical protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR033375|mint:Q9UFW8|refseq:XP_016862844.1 go:"GO:0003690"(double-stranded DNA binding) comment:fragment 823 from the human 28 S rRNA gene; nucleotides 8758–8817, GenBankTMaccession number U13369 comment:"human CGGBP1 wild type full length was used; species ascertained from PMID:9201980 which reports cloning of CGGBP1 from human-hela cells"|comment:several CGGBP1 deletions mutants were also assayed in the same experimenta, all had strongly reduced binding figure legend:Fig 1C|causality statement:Q9UFW8 inhibits expression at RNA level of ENSG00000102081|comment:"the DNA-probe used in the emsa interaction detection (rna28s) contains the same 5′-(CGG)n-3′ repeats as those found in the FMR1 region assayed in the reporter gene assay (see causality statement)"|comment:"CGGBP1 (Q9UFW8) decreases expression at mRNA level of FMR1 (ENSG00000102081) as ascertained by reporter gene assay in human-hela upon CGGBP1 overexpression"|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2014/05/22 2014/10/16 - rogid:1sg3JQWhmEQX9snN5SG1OjdRP1A9606 intact-crc:E95A5EDA42763FD3 false 32p radiolabel:?-? necessary binding region:14-167 - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography)