#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q62739 uniprotkb:O88764 intact:EBI-2028671|uniprotkb:A1L127|ensembl:ENSRNOP00000007258 intact:EBI-4404236|ensembl:ENSRNOP00000027634 psi-mi:rab3i_rat(display_long)|uniprotkb:Rab3ip(gene name)|psi-mi:Rab3ip(display_short)|uniprotkb:Rabin3(gene name synonym)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:Rabin8(gene name synonym) psi-mi:dapk3_rat(display_long)|uniprotkb:Dapk3(gene name)|psi-mi:Dapk3(display_short)|uniprotkb:Zipk(gene name synonym)|uniprotkb:DAP-like kinase(gene name synonym)|uniprotkb:ZIP-kinase(gene name synonym)|uniprotkb:MYPT1 kinase(gene name synonym) psi-mi:"MI:0018"(two hybrid) Page et al. (1999) pubmed:10602480|imex:IM-23048 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9692646|imex:IM-23048-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:620650|refseq:NP_059009.2|refseq:XP_006241419.1|refseq:XP_006241420.1|refseq:XP_006241421.1|refseq:XP_006241422.1|ensembl:ENSRNOG00000005362(gene)|ensembl:ENSRNOT00000007258(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0030027"(lamellipodium)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051020"(GTPase binding)|go:"GO:0051490"(negative regulation of filopodium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:1990635"(proximal dendrite)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|reactome:R-RNO-5620912|reactome:R-RNO-5620916|reactome:R-RNO-5620922|reactome:R-RNO-8876198 rgd:621766|refseq:NP_071991.1|refseq:XP_006241055.1|refseq:XP_017450587.1|refseq:XP_017450588.1|ensembl:ENSRNOG00000020383(gene)|ensembl:ENSRNOT00000027634(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0006325"(chromatin organization)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016301"(kinase activity)|go:"GO:0016605"(PML body)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043519"(regulation of myosin II filament organization)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042870 - - - figure legend:no figure|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/08/21 2021/02/11 rogid:xIGhMD0AZHp4HesXNftX6RaVv/o10116 rogid:OkaRX6OJSY0niph7AySJMUIj+2Y10116 intact-crc:72A1B9CBD513B2DA|rigid:r5KNFxaIZD2L7NrjAw1HrHKaslw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9ES19 uniprotkb:O88764 intact:EBI-9692615|ensembl:ENSRNOP00000060302 intact:EBI-4404236|ensembl:ENSRNOP00000027634 psi-mi:atf4_rat(display_long)|uniprotkb:Atf4(gene name)|psi-mi:Atf4(display_short)|uniprotkb:Activating transcription factor 4(gene name synonym) psi-mi:dapk3_rat(display_long)|uniprotkb:Dapk3(gene name)|psi-mi:Dapk3(display_short)|uniprotkb:Zipk(gene name synonym)|uniprotkb:DAP-like kinase(gene name synonym)|uniprotkb:ZIP-kinase(gene name synonym)|uniprotkb:MYPT1 kinase(gene name synonym) psi-mi:"MI:0018"(two hybrid) Page et al. (1999) pubmed:10602480|imex:IM-23048 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9692612|imex:IM-23048-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:621863|refseq:NP_077379.1|ensembl:ENSRNOG00000017801(gene)|ensembl:ENSRNOT00000065304(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030282"(bone mineralization)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032057"(negative regulation of translational initiation in response to stress)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0036091"(positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043267"(negative regulation of potassium ion transport)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070169"(positive regulation of biomineral tissue development)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:0070982"(L-asparagine metabolic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140467"(integrated stress response signaling)|go:"GO:0140468"(HRI-mediated signaling)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1990037"(Lewy body core)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990589"(ATF4-CREB1 transcription factor complex)|go:"GO:1990590"(ATF1-ATF4 transcription factor complex)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990737"(response to manganese-induced endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000120"(positive regulation of sodium-dependent phosphate transport)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029811|go:"GO:0048167"(regulation of synaptic plasticity) rgd:621766|refseq:NP_071991.1|refseq:XP_006241055.1|refseq:XP_017450587.1|refseq:XP_017450588.1|ensembl:ENSRNOG00000020383(gene)|ensembl:ENSRNOT00000027634(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0006325"(chromatin organization)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016301"(kinase activity)|go:"GO:0016605"(PML body)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043519"(regulation of myosin II filament organization)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042870 - - - figure legend:no figure|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/08/21 2014/10/16 rogid:dY5JhynAFdZrmRVxGx9evLeh4T410116 rogid:OkaRX6OJSY0niph7AySJMUIj+2Y10116 intact-crc:674791ACAD0E3E63|rigid:4yf8kEowlDC/ZzdXMxURxC8NlvA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q62627 uniprotkb:O88764 intact:EBI-1187240 intact:EBI-4404236|ensembl:ENSRNOP00000027634 psi-mi:pawr_rat(display_long)|uniprotkb:Prostate apoptosis response 4 protein(gene name synonym)|uniprotkb:Transcriptional repressor Par-4-like protein PAWR(gene name synonym)|uniprotkb:Pawr(gene name)|psi-mi:Pawr(display_short)|uniprotkb:Par4(gene name synonym) psi-mi:dapk3_rat(display_long)|uniprotkb:Dapk3(gene name)|psi-mi:Dapk3(display_short)|uniprotkb:Zipk(gene name synonym)|uniprotkb:DAP-like kinase(gene name synonym)|uniprotkb:ZIP-kinase(gene name synonym)|uniprotkb:MYPT1 kinase(gene name synonym) psi-mi:"MI:0018"(two hybrid) Page et al. (1999) pubmed:10602480|imex:IM-23048 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9692608|imex:IM-23048-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:69065|refseq:NP_277020.1|interpro:IPR026117|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0009611"(response to wounding)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042986"(positive regulation of amyloid precursor protein biosynthetic process)|go:"GO:0043005"(neuron projection)|go:"GO:0003779"(actin binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045760"(positive regulation of action potential)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0060450"(positive regulation of hindgut contraction)|go:"GO:0071306"(cellular response to vitamin E)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0090281"(negative regulation of calcium ion import)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:1901082"(positive regulation of relaxation of smooth muscle)|go:"GO:1901300"(positive regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1903238"(positive regulation of leukocyte tethering or rolling)|go:"GO:1904457"(positive regulation of neuronal action potential)|go:"GO:2000391"(positive regulation of neutrophil extravasation)|go:"GO:2000774"(positive regulation of cellular senescence)|rcsb pdb:5FIY rgd:621766|refseq:NP_071991.1|refseq:XP_006241055.1|refseq:XP_017450587.1|refseq:XP_017450588.1|ensembl:ENSRNOG00000020383(gene)|ensembl:ENSRNOT00000027634(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0006325"(chromatin organization)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016301"(kinase activity)|go:"GO:0016605"(PML body)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043519"(regulation of myosin II filament organization)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042870 - - - figure legend:no figure|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/08/21 2014/10/16 rogid:wNH2PrL9GaukUQg1Gc+3Q+h0sB010116 rogid:OkaRX6OJSY0niph7AySJMUIj+2Y10116 intact-crc:B49F57B9F5D8A9AF|rigid:l3AlVQiId2vUW4omOCMWTIz7az8 false sufficient binding region:137-332 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O88764 uniprotkb:Q62627 intact:EBI-4404236|ensembl:ENSRNOP00000027634 intact:EBI-1187240 psi-mi:dapk3_rat(display_long)|uniprotkb:Dapk3(gene name)|psi-mi:Dapk3(display_short)|uniprotkb:Zipk(gene name synonym)|uniprotkb:DAP-like kinase(gene name synonym)|uniprotkb:ZIP-kinase(gene name synonym)|uniprotkb:MYPT1 kinase(gene name synonym) psi-mi:pawr_rat(display_long)|uniprotkb:Prostate apoptosis response 4 protein(gene name synonym)|uniprotkb:Transcriptional repressor Par-4-like protein PAWR(gene name synonym)|uniprotkb:Pawr(gene name)|psi-mi:Pawr(display_short)|uniprotkb:Par4(gene name synonym) psi-mi:"MI:0018"(two hybrid) Page et al. (1999) pubmed:10602480|imex:IM-23048 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9692659|imex:IM-23048-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:621766|refseq:NP_071991.1|refseq:XP_006241055.1|refseq:XP_017450587.1|refseq:XP_017450588.1|ensembl:ENSRNOG00000020383(gene)|ensembl:ENSRNOT00000027634(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0006325"(chromatin organization)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016301"(kinase activity)|go:"GO:0016605"(PML body)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043519"(regulation of myosin II filament organization)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042870 rgd:69065|refseq:NP_277020.1|interpro:IPR026117|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0009611"(response to wounding)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042986"(positive regulation of amyloid precursor protein biosynthetic process)|go:"GO:0043005"(neuron projection)|go:"GO:0003779"(actin binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045760"(positive regulation of action potential)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0060450"(positive regulation of hindgut contraction)|go:"GO:0071306"(cellular response to vitamin E)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0090281"(negative regulation of calcium ion import)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:1901082"(positive regulation of relaxation of smooth muscle)|go:"GO:1901300"(positive regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1903238"(positive regulation of leukocyte tethering or rolling)|go:"GO:1904457"(positive regulation of neuronal action potential)|go:"GO:2000391"(positive regulation of neutrophil extravasation)|go:"GO:2000774"(positive regulation of cellular senescence)|rcsb pdb:5FIY - - - figure legend:1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/08/21 2014/10/16 rogid:OkaRX6OJSY0niph7AySJMUIj+2Y10116 rogid:wNH2PrL9GaukUQg1Gc+3Q+h0sB010116 intact-crc:4E1998806A2CA26F|rigid:l3AlVQiId2vUW4omOCMWTIz7az8 false sufficient binding region:1-417|necessary binding region:338-417 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q62627 uniprotkb:O88764 intact:EBI-1187240 intact:EBI-4404236|ensembl:ENSRNOP00000027634 psi-mi:pawr_rat(display_long)|uniprotkb:Prostate apoptosis response 4 protein(gene name synonym)|uniprotkb:Transcriptional repressor Par-4-like protein PAWR(gene name synonym)|uniprotkb:Pawr(gene name)|psi-mi:Pawr(display_short)|uniprotkb:Par4(gene name synonym) psi-mi:dapk3_rat(display_long)|uniprotkb:Dapk3(gene name)|psi-mi:Dapk3(display_short)|uniprotkb:Zipk(gene name synonym)|uniprotkb:DAP-like kinase(gene name synonym)|uniprotkb:ZIP-kinase(gene name synonym)|uniprotkb:MYPT1 kinase(gene name synonym) psi-mi:"MI:0096"(pull down) Page et al. (1999) pubmed:10602480|imex:IM-23048 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9692705|imex:IM-23048-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:69065|refseq:NP_277020.1|interpro:IPR026117|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0009611"(response to wounding)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042986"(positive regulation of amyloid precursor protein biosynthetic process)|go:"GO:0043005"(neuron projection)|go:"GO:0003779"(actin binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045760"(positive regulation of action potential)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0060450"(positive regulation of hindgut contraction)|go:"GO:0071306"(cellular response to vitamin E)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0090281"(negative regulation of calcium ion import)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:1901082"(positive regulation of relaxation of smooth muscle)|go:"GO:1901300"(positive regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1903238"(positive regulation of leukocyte tethering or rolling)|go:"GO:1904457"(positive regulation of neuronal action potential)|go:"GO:2000391"(positive regulation of neutrophil extravasation)|go:"GO:2000774"(positive regulation of cellular senescence)|rcsb pdb:5FIY rgd:621766|refseq:NP_071991.1|refseq:XP_006241055.1|refseq:XP_017450587.1|refseq:XP_017450588.1|ensembl:ENSRNOG00000020383(gene)|ensembl:ENSRNOT00000027634(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0006325"(chromatin organization)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016301"(kinase activity)|go:"GO:0016605"(PML body)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043519"(regulation of myosin II filament organization)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042870 - - - figure legend:2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/08/21 2014/10/16 rogid:wNH2PrL9GaukUQg1Gc+3Q+h0sB010116 rogid:OkaRX6OJSY0niph7AySJMUIj+2Y10116 intact-crc:088FFCB9BCEEA280|rigid:l3AlVQiId2vUW4omOCMWTIz7az8 false sufficient binding region:137-332|glutathione s tranferase tag:?-? 35s radiolabel:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:O88764 uniprotkb:O88764 intact:EBI-4404236|ensembl:ENSRNOP00000027634 intact:EBI-4404236|ensembl:ENSRNOP00000027634 psi-mi:dapk3_rat(display_long)|uniprotkb:Dapk3(gene name)|psi-mi:Dapk3(display_short)|uniprotkb:Zipk(gene name synonym)|uniprotkb:DAP-like kinase(gene name synonym)|uniprotkb:ZIP-kinase(gene name synonym)|uniprotkb:MYPT1 kinase(gene name synonym) psi-mi:dapk3_rat(display_long)|uniprotkb:Dapk3(gene name)|psi-mi:Dapk3(display_short)|uniprotkb:Zipk(gene name synonym)|uniprotkb:DAP-like kinase(gene name synonym)|uniprotkb:ZIP-kinase(gene name synonym)|uniprotkb:MYPT1 kinase(gene name synonym) psi-mi:"MI:0424"(protein kinase assay) Page et al. (1999) pubmed:10602480|imex:IM-23048 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9692773|imex:IM-23048-7 - - psi-mi:"MI:0898"(putative self) psi-mi:"MI:0898"(putative self) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:621766|refseq:NP_071991.1|refseq:XP_006241055.1|refseq:XP_017450587.1|refseq:XP_017450588.1|ensembl:ENSRNOG00000020383(gene)|ensembl:ENSRNOT00000027634(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0006325"(chromatin organization)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016301"(kinase activity)|go:"GO:0016605"(PML body)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043519"(regulation of myosin II filament organization)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042870 rgd:621766|refseq:NP_071991.1|refseq:XP_006241055.1|refseq:XP_017450587.1|refseq:XP_017450588.1|ensembl:ENSRNOG00000020383(gene)|ensembl:ENSRNOT00000027634(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0006325"(chromatin organization)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016301"(kinase activity)|go:"GO:0016605"(PML body)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043519"(regulation of myosin II filament organization)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042870 go:"GO:0046777"(protein autophosphorylation) - - figure legend:3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/08/21 2014/10/16 rogid:OkaRX6OJSY0niph7AySJMUIj+2Y10116 rogid:OkaRX6OJSY0niph7AySJMUIj+2Y10116 intact-crc:BEFD0626639C6416|rigid:NWXDTtP9xe1M9ipiQdH0sv/Q11E false sufficient binding region:1-337|his tag:n-n sufficient binding region:1-337|his tag:n-n - 0 psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q62627 uniprotkb:O88764 intact:EBI-1187240 intact:EBI-4404236|ensembl:ENSRNOP00000027634 psi-mi:pawr_rat(display_long)|uniprotkb:Prostate apoptosis response 4 protein(gene name synonym)|uniprotkb:Transcriptional repressor Par-4-like protein PAWR(gene name synonym)|uniprotkb:Pawr(gene name)|psi-mi:Pawr(display_short)|uniprotkb:Par4(gene name synonym) psi-mi:dapk3_rat(display_long)|uniprotkb:Dapk3(gene name)|psi-mi:Dapk3(display_short)|uniprotkb:Zipk(gene name synonym)|uniprotkb:DAP-like kinase(gene name synonym)|uniprotkb:ZIP-kinase(gene name synonym)|uniprotkb:MYPT1 kinase(gene name synonym) psi-mi:"MI:0424"(protein kinase assay) Page et al. (1999) pubmed:10602480|imex:IM-23048 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9692757|imex:IM-23048-6 - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:69065|refseq:NP_277020.1|interpro:IPR026117|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0009611"(response to wounding)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042986"(positive regulation of amyloid precursor protein biosynthetic process)|go:"GO:0043005"(neuron projection)|go:"GO:0003779"(actin binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045760"(positive regulation of action potential)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0060450"(positive regulation of hindgut contraction)|go:"GO:0071306"(cellular response to vitamin E)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0090281"(negative regulation of calcium ion import)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:1901082"(positive regulation of relaxation of smooth muscle)|go:"GO:1901300"(positive regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1903238"(positive regulation of leukocyte tethering or rolling)|go:"GO:1904457"(positive regulation of neuronal action potential)|go:"GO:2000391"(positive regulation of neutrophil extravasation)|go:"GO:2000774"(positive regulation of cellular senescence)|rcsb pdb:5FIY rgd:621766|refseq:NP_071991.1|refseq:XP_006241055.1|refseq:XP_017450587.1|refseq:XP_017450588.1|ensembl:ENSRNOG00000020383(gene)|ensembl:ENSRNOT00000027634(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0006325"(chromatin organization)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016301"(kinase activity)|go:"GO:0016605"(PML body)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043519"(regulation of myosin II filament organization)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042870 go:"GO:0006468"(protein phosphorylation)|go:"GO:0004672"(protein kinase activity) - - figure legend:3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/08/21 2014/10/16 rogid:wNH2PrL9GaukUQg1Gc+3Q+h0sB010116 rogid:OkaRX6OJSY0niph7AySJMUIj+2Y10116 intact-crc:92D58F0D42EE4C43|rigid:l3AlVQiId2vUW4omOCMWTIz7az8 false sufficient binding region:137-332|glutathione s tranferase tag:?-? his tag:n-n|sufficient binding region:1-337 - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:O88764 uniprotkb:Q62627 intact:EBI-4404236|ensembl:ENSRNOP00000027634 intact:EBI-1187240 psi-mi:dapk3_rat(display_long)|uniprotkb:Dapk3(gene name)|psi-mi:Dapk3(display_short)|uniprotkb:Zipk(gene name synonym)|uniprotkb:DAP-like kinase(gene name synonym)|uniprotkb:ZIP-kinase(gene name synonym)|uniprotkb:MYPT1 kinase(gene name synonym) psi-mi:pawr_rat(display_long)|uniprotkb:Prostate apoptosis response 4 protein(gene name synonym)|uniprotkb:Transcriptional repressor Par-4-like protein PAWR(gene name synonym)|uniprotkb:Pawr(gene name)|psi-mi:Pawr(display_short)|uniprotkb:Par4(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Page et al. (1999) pubmed:10602480|imex:IM-23048 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9692791|imex:IM-23048-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:621766|refseq:NP_071991.1|refseq:XP_006241055.1|refseq:XP_017450587.1|refseq:XP_017450588.1|ensembl:ENSRNOG00000020383(gene)|ensembl:ENSRNOT00000027634(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0006325"(chromatin organization)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016301"(kinase activity)|go:"GO:0016605"(PML body)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043519"(regulation of myosin II filament organization)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042870 rgd:69065|refseq:NP_277020.1|interpro:IPR026117|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0009611"(response to wounding)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042986"(positive regulation of amyloid precursor protein biosynthetic process)|go:"GO:0043005"(neuron projection)|go:"GO:0003779"(actin binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045760"(positive regulation of action potential)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0060450"(positive regulation of hindgut contraction)|go:"GO:0071306"(cellular response to vitamin E)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0090281"(negative regulation of calcium ion import)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:1901082"(positive regulation of relaxation of smooth muscle)|go:"GO:1901300"(positive regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1903238"(positive regulation of leukocyte tethering or rolling)|go:"GO:1904457"(positive regulation of neuronal action potential)|go:"GO:2000391"(positive regulation of neutrophil extravasation)|go:"GO:2000774"(positive regulation of cellular senescence)|rcsb pdb:5FIY go:"GO:0005884"(actin filament) - - figure legend:5 and 7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-ref52)|taxid:10116(Rattus norvegicus embryonic fibroblast cells) - 2014/08/21 2014/10/16 rogid:OkaRX6OJSY0niph7AySJMUIj+2Y10116 rogid:wNH2PrL9GaukUQg1Gc+3Q+h0sB010116 intact-crc:F04860B6F459A61B|rigid:l3AlVQiId2vUW4omOCMWTIz7az8 false green fluorescent protein tag:n-n|mutation disrupting interaction:42-42 necessary binding region:3-239 - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0422"(immunostaining)