#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P18088	uniprotkb:P18088	intact:EBI-9397328|ensembl:ENSRNOP00000000008|ensembl:ENSRNOP00000072778	intact:EBI-9397328|ensembl:ENSRNOP00000000008|ensembl:ENSRNOP00000072778	psi-mi:dce1_rat(display_long)|uniprotkb:Gad1(gene name)|psi-mi:Gad1(display_short)|uniprotkb:Gad67(gene name synonym)|uniprotkb:67 kDa glutamic acid decarboxylase(gene name synonym)|uniprotkb:Glutamate decarboxylase 67 kDa isoform(gene name synonym)	psi-mi:dce1_rat(display_long)|uniprotkb:Gad1(gene name)|psi-mi:Gad1(display_short)|uniprotkb:Gad67(gene name synonym)|uniprotkb:67 kDa glutamic acid decarboxylase(gene name synonym)|uniprotkb:Glutamate decarboxylase 67 kDa isoform(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Kanaani et al. (1999)	pubmed:10601283|imex:IM-22508	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9397309|imex:IM-22508-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:2652|refseq:NP_058703.1|refseq:XP_017446943.1|refseq:XP_017446944.1|ensembl:ENSRNOG00000000007(gene)|ensembl:ENSRNOT00000000008(transcript)|ensembl:ENSRNOT00000087712(transcript)|go:"GO:0004351"(glutamate decarboxylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0009449"(gamma-aminobutyric acid biosynthetic process)|go:"GO:0016595"(glutamate binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030424"(axon)|go:"GO:0035176"(social behavior)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042493"|go:"GO:0043679"(axon terminus)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0060077"(inhibitory synapse)|interpro:IPR002129(Pyridoxal phosphate-dependent decarboxylase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR021115|reactome:R-RNO-888568|reactome:R-RNO-888590	rgd:2652|refseq:NP_058703.1|refseq:XP_017446943.1|refseq:XP_017446944.1|ensembl:ENSRNOG00000000007(gene)|ensembl:ENSRNOT00000000008(transcript)|ensembl:ENSRNOT00000087712(transcript)|go:"GO:0004351"(glutamate decarboxylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0009449"(gamma-aminobutyric acid biosynthetic process)|go:"GO:0016595"(glutamate binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030424"(axon)|go:"GO:0035176"(social behavior)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042493"|go:"GO:0043679"(axon terminus)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0060077"(inhibitory synapse)|interpro:IPR002129(Pyridoxal phosphate-dependent decarboxylase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR021115|reactome:R-RNO-888568|reactome:R-RNO-888590	-	-	-	figure legend:Fig. 2a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2014/04/23	2014/10/16	rogid:mjZ0+R1FJiyxUGWxsY7JjyG3L/g10116	rogid:mjZ0+R1FJiyxUGWxsY7JjyG3L/g10116	intact-crc:60077F204BD80FC2|rigid:kUye1BLh9ge/2YQ4io3vjpkFuOg	false	sufficient binding region:39-593|mutation:45-45	-	1	1	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P48320	uniprotkb:P18088	intact:EBI-8313192|ensembl:ENSMUSP00000028123|uniprotkb:O35519|intact:MINT-4092881	intact:EBI-9397328|ensembl:ENSRNOP00000000008|ensembl:ENSRNOP00000072778	psi-mi:dce2_mouse(display_long)|uniprotkb:Gad2(gene name)|psi-mi:Gad2(display_short)|uniprotkb:Gad65(gene name synonym)|uniprotkb:Glutamate decarboxylase 65 kDa isoform(gene name synonym)|uniprotkb:65 kDa glutamic acid decarboxylase(gene name synonym)	psi-mi:dce1_rat(display_long)|uniprotkb:Gad1(gene name)|psi-mi:Gad1(display_short)|uniprotkb:Gad67(gene name synonym)|uniprotkb:67 kDa glutamic acid decarboxylase(gene name synonym)|uniprotkb:Glutamate decarboxylase 67 kDa isoform(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Kanaani et al. (1999)	pubmed:10601283|imex:IM-22508	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9397387|imex:IM-22508-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-MMU-888568|reactome:R-MMU-888590|mint:P48320|ensembl:ENSMUSG00000026787(gene)|ensembl:ENSMUST00000028123(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004351"(glutamate decarboxylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006540"(glutamate decarboxylation to succinate)|go:"GO:0016595"(glutamate binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042493"|go:"GO:0042734"(presynaptic membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|interpro:IPR002129(Pyridoxal phosphate-dependent decarboxylase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR021115|refseq:NP_032104.2	rgd:2652|refseq:NP_058703.1|refseq:XP_017446943.1|refseq:XP_017446944.1|ensembl:ENSRNOG00000000007(gene)|ensembl:ENSRNOT00000000008(transcript)|ensembl:ENSRNOT00000087712(transcript)|go:"GO:0004351"(glutamate decarboxylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0009449"(gamma-aminobutyric acid biosynthetic process)|go:"GO:0016595"(glutamate binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030424"(axon)|go:"GO:0035176"(social behavior)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042493"|go:"GO:0043679"(axon terminus)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0060077"(inhibitory synapse)|interpro:IPR002129(Pyridoxal phosphate-dependent decarboxylase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR021115|reactome:R-RNO-888568|reactome:R-RNO-888590	-	function:Catalyzes the production of GABA|comment:mint	-	figure legend:Fig. 3b, lanes 6 & 10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2014/04/23	2014/10/16	rogid:0VtYatqrgqWv8rg1ri4TP+Ap8KE10090	rogid:mjZ0+R1FJiyxUGWxsY7JjyG3L/g10116	intact-crc:EF5F0B6CC7A70EDC|rigid:Y0GufiM2tWGMhUqPWEUT42W03ig	false	-	sufficient binding region:102-593	1	1	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P18088	uniprotkb:Q05683	intact:EBI-9397328|ensembl:ENSRNOP00000000008|ensembl:ENSRNOP00000072778	intact:EBI-9397355|ensembl:ENSRNOP00000024901	psi-mi:dce1_rat(display_long)|uniprotkb:Gad1(gene name)|psi-mi:Gad1(display_short)|uniprotkb:Gad67(gene name synonym)|uniprotkb:67 kDa glutamic acid decarboxylase(gene name synonym)|uniprotkb:Glutamate decarboxylase 67 kDa isoform(gene name synonym)	psi-mi:dce2_rat(display_long)|uniprotkb:Gad2(gene name)|psi-mi:Gad2(display_short)|uniprotkb:Gad65(gene name synonym)|uniprotkb:65 kDa glutamic acid decarboxylase(gene name synonym)|uniprotkb:Glutamate decarboxylase 65 kDa isoform(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Kanaani et al. (1999)	pubmed:10601283|imex:IM-22508	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9397422|imex:IM-22508-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:2652|refseq:NP_058703.1|refseq:XP_017446943.1|refseq:XP_017446944.1|ensembl:ENSRNOG00000000007(gene)|ensembl:ENSRNOT00000000008(transcript)|ensembl:ENSRNOT00000087712(transcript)|go:"GO:0004351"(glutamate decarboxylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0009449"(gamma-aminobutyric acid biosynthetic process)|go:"GO:0016595"(glutamate binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030424"(axon)|go:"GO:0035176"(social behavior)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042493"|go:"GO:0043679"(axon terminus)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0060077"(inhibitory synapse)|interpro:IPR002129(Pyridoxal phosphate-dependent decarboxylase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR021115|reactome:R-RNO-888568|reactome:R-RNO-888590	rgd:2653|refseq:NP_036695.1|ensembl:ENSRNOG00000018200(gene)|ensembl:ENSRNOT00000024901(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004351"(glutamate decarboxylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006540"(glutamate decarboxylation to succinate)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0016595"(glutamate binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042493"|go:"GO:0042734"(presynaptic membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060077"(inhibitory synapse)|interpro:IPR002129(Pyridoxal phosphate-dependent decarboxylase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR021115|rcsb pdb:3CUP|reactome:R-RNO-888568|reactome:R-RNO-888590	-	-	-	figure legend:Fig. 3a|comment:The interaction is detected in both the cytosolic and membrane fraction.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2014/04/23	2014/10/16	rogid:mjZ0+R1FJiyxUGWxsY7JjyG3L/g10116	rogid:/fVDGb/OFt1ZZnv36p7bExtb8+410116	intact-crc:6E2C5F2514CB05AD|rigid:8ray7zCfac8e849EZQUgsZi7eAM	false	-	-	1	1	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q05683	uniprotkb:P18088	intact:EBI-9397355|ensembl:ENSRNOP00000024901	intact:EBI-9397328|ensembl:ENSRNOP00000000008|ensembl:ENSRNOP00000072778	psi-mi:dce2_rat(display_long)|uniprotkb:Gad2(gene name)|psi-mi:Gad2(display_short)|uniprotkb:Gad65(gene name synonym)|uniprotkb:65 kDa glutamic acid decarboxylase(gene name synonym)|uniprotkb:Glutamate decarboxylase 65 kDa isoform(gene name synonym)	psi-mi:dce1_rat(display_long)|uniprotkb:Gad1(gene name)|psi-mi:Gad1(display_short)|uniprotkb:Gad67(gene name synonym)|uniprotkb:67 kDa glutamic acid decarboxylase(gene name synonym)|uniprotkb:Glutamate decarboxylase 67 kDa isoform(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Kanaani et al. (1999)	pubmed:10601283|imex:IM-22508	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9397445|imex:IM-22508-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:2653|refseq:NP_036695.1|ensembl:ENSRNOG00000018200(gene)|ensembl:ENSRNOT00000024901(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004351"(glutamate decarboxylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006540"(glutamate decarboxylation to succinate)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0016595"(glutamate binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042493"|go:"GO:0042734"(presynaptic membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060077"(inhibitory synapse)|interpro:IPR002129(Pyridoxal phosphate-dependent decarboxylase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR021115|rcsb pdb:3CUP|reactome:R-RNO-888568|reactome:R-RNO-888590	rgd:2652|refseq:NP_058703.1|refseq:XP_017446943.1|refseq:XP_017446944.1|ensembl:ENSRNOG00000000007(gene)|ensembl:ENSRNOT00000000008(transcript)|ensembl:ENSRNOT00000087712(transcript)|go:"GO:0004351"(glutamate decarboxylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0009449"(gamma-aminobutyric acid biosynthetic process)|go:"GO:0016595"(glutamate binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030424"(axon)|go:"GO:0035176"(social behavior)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042493"|go:"GO:0043679"(axon terminus)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0060077"(inhibitory synapse)|interpro:IPR002129(Pyridoxal phosphate-dependent decarboxylase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR021115|reactome:R-RNO-888568|reactome:R-RNO-888590	go:"GO:0008021"(synaptic vesicle)	-	-	figure legend:Fig. 6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-hippocampus)|taxid:10116(Hippocampus of rat brain)	-	2014/04/23	2014/10/16	rogid:/fVDGb/OFt1ZZnv36p7bExtb8+410116	rogid:mjZ0+R1FJiyxUGWxsY7JjyG3L/g10116	intact-crc:7E81B513F268BCD4|rigid:8ray7zCfac8e849EZQUgsZi7eAM	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)