#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9ESN9	uniprotkb:Q61831	intact:EBI-301496|uniprotkb:Q99KU7|uniprotkb:Q9EQD8|uniprotkb:Q9ESN7|uniprotkb:Q9ESN8|uniprotkb:Q9ESP0|uniprotkb:Q9JLH2|uniprotkb:Q9JLH3|uniprotkb:Q9R0U7|uniprotkb:Q5D062|ensembl:ENSMUSP00000085683|ensembl:ENSMUSP00000114802	intact:EBI-400741|uniprotkb:Q9R0U6	psi-mi:jip3_mouse(display_long)|uniprotkb:Syd2(gene name synonym)|uniprotkb:Mapk8ip3(gene name)|psi-mi:Mapk8ip3(display_short)|uniprotkb:Jip3(gene name synonym)|uniprotkb:Jsap1(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 3(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 3(gene name synonym)|uniprotkb:JNK/SAPK-associated protein 1(gene name synonym)|uniprotkb:Sunday driver 2(gene name synonym)	psi-mi:mk10_mouse(display_long)|uniprotkb:Mapk10(gene name)|psi-mi:Mapk10(display_short)|uniprotkb:Jnk3(gene name synonym)|uniprotkb:Prkm10(gene name synonym)|uniprotkb:Serk2(gene name synonym)|uniprotkb:Stress-activated protein kinase JNK3(gene name synonym)|uniprotkb:c-Jun N-terminal kinase 3(gene name synonym)|uniprotkb:MAP kinase p49 3F12(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Ito et al. (1999)	imex:IM-22967|pubmed:10523642	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-9549269|imex:IM-22967-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000024163(gene)|ensembl:ENSMUST00000088345(transcript)|ensembl:ENSMUST00000146923(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0007254"(JNK cascade)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0007411"(axon guidance)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008104"(protein localization)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030673"(axolemma)|go:"GO:0030900"(forebrain development)|go:"GO:0031103"(axon regeneration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044297"(cell body)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0061564"(axon development)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019143|interpro:IPR032486|interpro:IPR034743|interpro:IPR034744|interpro:IPR036322|interpro:IPR039911|mint:Q9ESN9|rcsb pdb:6EJN|refseq:NP_001156919.1|refseq:NP_001156920.1|refseq:NP_001156921.1|refseq:NP_001156923.1|refseq:NP_038959.2	interpro:IPR008351(JNK MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|refseq:XP_017176379.1|refseq:NP_001297615.1|refseq:XP_017176380.1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004705"(JUN kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007254"(JNK cascade)|go:"GO:0007258"(JUN phosphorylation)|go:"GO:0009416"(response to light stimulus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0098969"(neurotransmitter receptor transport to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|reactome:R-MMU-2559580|reactome:R-MMU-2871796|reactome:R-MMU-450321|reactome:R-MMU-450341	-	-	-	dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/06/11	2014/10/16	rogid:cY52UF0SczUqoiT9Cnb97na8cLg10090	rogid:5x8VKNSD0AmjnO8BgrewNT2Ypb810090	intact-crc:98CBC436184B4C95|rigid:pf7nSDBIM2FOuoBcchaJiOFymE4	false	sufficient binding region:?-?	-	-	-	psi-mi:"MI:0056"(full identification by DNA sequencing)	psi-mi:"MI:0056"(full identification by DNA sequencing)
uniprotkb:Q9WTU6	uniprotkb:Q9ESN9-2	intact:EBI-298798|ensembl:ENSMUSP00000042744|ensembl:ENSMUSP00000136977|uniprotkb:Q8C097|uniprotkb:Q8VDD2|uniprotkb:Q9WTU4|uniprotkb:Q9WTU5|uniprotkb:Q5NCK9|uniprotkb:Q5NCL5	intact:EBI-9549291|ensembl:ENSMUSP00000112955	psi-mi:mk09_mouse(display_long)|uniprotkb:Mapk9(gene name)|psi-mi:Mapk9(display_short)|uniprotkb:Jnk2(gene name synonym)|uniprotkb:Prkm9(gene name synonym)|uniprotkb:Stress-activated protein kinase JNK2(gene name synonym)|uniprotkb:c-Jun N-terminal kinase 2(gene name synonym)	psi-mi:q9esn9-2(display_long)|uniprotkb:Mapk8ip3(gene name)|psi-mi:Mapk8ip3(display_short)|uniprotkb:Jip3(gene name synonym)|uniprotkb:Jsap1(gene name synonym)|uniprotkb:Syd2(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 3(gene name synonym)|uniprotkb:JNK/SAPK-associated protein 1(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 3(gene name synonym)|uniprotkb:Sunday driver 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ito et al. (1999)	imex:IM-22967|pubmed:10523642	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-9549854|imex:IM-22967-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000020366(gene)|ensembl:ENSMUST00000043321(transcript)|ensembl:ENSMUST00000178543(transcript)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004705"(JUN kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007254"(JNK cascade)|go:"GO:0007258"(JUN phosphorylation)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0004672"(protein kinase activity)|go:"GO:0010744"(positive regulation of macrophage derived foam cell differentiation)|go:"GO:0010770"(positive regulation of cell morphogenesis involved in differentiation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031175"(neuron projection development)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0042493"|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0048511"(rhythmic process)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0061833"(protein localization to tricellular tight junction)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901485"(positive regulation of transcription factor catabolic process)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008351(JNK MAP kinase)|interpro:IPR011009(Protein kinase-like)|reactome:R-MMU-2559580|reactome:R-MMU-2871796|reactome:R-MMU-450321|reactome:R-MMU-450341|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032308"(positive regulation of prostaglandin secretion)|go:"GO:0032722"(positive regulation of chemokine production)|refseq:NP_001157143.1|refseq:NP_001157144.1|refseq:NP_058657.1|refseq:NP_997575.2|ensembl:ENSMUSG00000020366|dip:DIP-31076N	ensembl:ENSMUSG00000024163(gene)|ensembl:ENSMUST00000119115(transcript)|intact:EBI-301496(isoform-parent)	-	-	-	figure legend:Fig. 2A|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2014/06/11	2014/10/16	rogid:m/9TybdDExPF8ah6GnnWDbHSgyA10090	rogid:Gw0J1by2qB5lEjidH2opKY1hePk10090	intact-crc:CBF72AC097D83632|rigid:VDLrbZzHPVVlFUEM3Sj14Jp6/3k	false	flag tag:n-n	s tag:n-n|his tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9ESN9-2	uniprotkb:Q91Y86	intact:EBI-9549291|ensembl:ENSMUSP00000112955	intact:EBI-298784|ensembl:ENSMUSP00000107576	psi-mi:q9esn9-2(display_long)|uniprotkb:Mapk8ip3(gene name)|psi-mi:Mapk8ip3(display_short)|uniprotkb:Jip3(gene name synonym)|uniprotkb:Jsap1(gene name synonym)|uniprotkb:Syd2(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 3(gene name synonym)|uniprotkb:JNK/SAPK-associated protein 1(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 3(gene name synonym)|uniprotkb:Sunday driver 2(gene name synonym)	psi-mi:mk08_mouse(display_long)|uniprotkb:Mapk8(gene name)|psi-mi:Mapk8(display_short)|uniprotkb:Jnk1(gene name synonym)|uniprotkb:Prkm8(gene name synonym)|uniprotkb:Stress-activated protein kinase JNK1(gene name synonym)|uniprotkb:c-Jun N-terminal kinase 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ito et al. (1999)	imex:IM-22967|pubmed:10523642	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-9549815|imex:IM-22967-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000024163(gene)|ensembl:ENSMUST00000119115(transcript)|intact:EBI-301496(isoform-parent)	go:"GO:0009411"(response to UV)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019894"(kinesin binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031175"(neuron projection development)|go:"GO:0031281"(positive regulation of cyclase activity)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031982"(vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034352"(positive regulation of glial cell apoptotic process)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035033"(histone deacetylase regulator activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0046605"(regulation of centrosome cycle)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0048263"(determination of dorsal identity)|go:"GO:0048511"(rhythmic process)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0061833"(protein localization to tricellular tight junction)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0090045"(positive regulation of deacetylase activity)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0097441"(basal dendrite)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901485"(positive regulation of transcription factor catabolic process)|go:"GO:1902595"(regulation of DNA replication origin binding)|go:"GO:1904809"(regulation of dense core granule transport)|go:"GO:2000017"(positive regulation of determination of dorsal identity)|go:"GO:2001224"(positive regulation of neuron migration)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008351(JNK MAP kinase)|interpro:IPR011009(Protein kinase-like)|mint:Q91Y86|reactome:R-MMU-139910|reactome:R-MMU-193648|reactome:R-MMU-2559580|reactome:R-MMU-2871796|reactome:R-MMU-376172|reactome:R-MMU-450321|reactome:R-MMU-450341|reactome:R-MMU-5693565|reactome:R-MMU-9007892|reactome:R-MMU-111446|ensembl:ENSMUSG00000021936(gene)|ensembl:ENSMUST00000111945(transcript)|go:"GO:0001503"(ossification)|go:"GO:0001764"(neuron migration)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002102"(podosome)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004705"(JUN kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007165"(signal transduction)|go:"GO:0007254"(JNK cascade)|go:"GO:0007258"(JUN phosphorylation)|go:"GO:0009408"(response to heat)|refseq:NP_057909.1|dip:DIP-31075N	-	-	-	figure legend:Fig. 2A|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2014/06/11	2014/10/16	rogid:Gw0J1by2qB5lEjidH2opKY1hePk10090	rogid:PF6G6rHf26jidt+Mg3aFCvCm7pU10090	intact-crc:54F2CB3DE27B53E8|rigid:MIGML8cN3OFVbqfBPh9GBKZSIE4	false	his tag:n-n|s tag:n-n	flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q61831	uniprotkb:Q9ESN9-2	intact:EBI-400741|uniprotkb:Q9R0U6	intact:EBI-9549291|ensembl:ENSMUSP00000112955	psi-mi:mk10_mouse(display_long)|uniprotkb:Mapk10(gene name)|psi-mi:Mapk10(display_short)|uniprotkb:Jnk3(gene name synonym)|uniprotkb:Prkm10(gene name synonym)|uniprotkb:Serk2(gene name synonym)|uniprotkb:Stress-activated protein kinase JNK3(gene name synonym)|uniprotkb:c-Jun N-terminal kinase 3(gene name synonym)|uniprotkb:MAP kinase p49 3F12(gene name synonym)	psi-mi:q9esn9-2(display_long)|uniprotkb:Mapk8ip3(gene name)|psi-mi:Mapk8ip3(display_short)|uniprotkb:Jip3(gene name synonym)|uniprotkb:Jsap1(gene name synonym)|uniprotkb:Syd2(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 3(gene name synonym)|uniprotkb:JNK/SAPK-associated protein 1(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 3(gene name synonym)|uniprotkb:Sunday driver 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ito et al. (1999)	imex:IM-22967|pubmed:10523642	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-9549479|imex:IM-22967-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR008351(JNK MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|refseq:XP_017176379.1|refseq:NP_001297615.1|refseq:XP_017176380.1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004705"(JUN kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007254"(JNK cascade)|go:"GO:0007258"(JUN phosphorylation)|go:"GO:0009416"(response to light stimulus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0098969"(neurotransmitter receptor transport to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|reactome:R-MMU-2559580|reactome:R-MMU-2871796|reactome:R-MMU-450321|reactome:R-MMU-450341	ensembl:ENSMUSG00000024163(gene)|ensembl:ENSMUST00000119115(transcript)|intact:EBI-301496(isoform-parent)	-	-	-	figure legend:Fig. 2A|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2014/06/11	2014/10/16	rogid:5x8VKNSD0AmjnO8BgrewNT2Ypb810090	rogid:Gw0J1by2qB5lEjidH2opKY1hePk10090	intact-crc:E6A838B422CC482B|rigid:+17vvqWT5Yd2fSlLeLlD/ZdTSZg	false	flag tag:n-n	his tag:n-n|s tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9ESN9-2	uniprotkb:P47809	intact:EBI-9549291|ensembl:ENSMUSP00000112955	intact:EBI-447934|ensembl:ENSMUSP00000041282	psi-mi:q9esn9-2(display_long)|uniprotkb:Mapk8ip3(gene name)|psi-mi:Mapk8ip3(display_short)|uniprotkb:Jip3(gene name synonym)|uniprotkb:Jsap1(gene name synonym)|uniprotkb:Syd2(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 3(gene name synonym)|uniprotkb:JNK/SAPK-associated protein 1(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 3(gene name synonym)|uniprotkb:Sunday driver 2(gene name synonym)	psi-mi:mp2k4_mouse(display_long)|uniprotkb:MAPK/ERK kinase 4(gene name synonym)|uniprotkb:JNK-activating kinase 1(gene name synonym)|uniprotkb:C-JUN N-terminal kinase kinase 1(gene name synonym)|uniprotkb:SAPK/ERK kinase 1(gene name synonym)|uniprotkb:Map2k4(gene name)|psi-mi:Map2k4(display_short)|uniprotkb:Jnkk1(gene name synonym)|uniprotkb:Prkmk4(gene name synonym)|uniprotkb:Sek1(gene name synonym)|uniprotkb:Serk1(gene name synonym)|uniprotkb:Skk1(gene name synonym)|uniprotkb:Mkk4(gene name synonym)|uniprotkb:Mek4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ito et al. (1999)	imex:IM-22967|pubmed:10523642	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-9549947|imex:IM-22967-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000024163(gene)|ensembl:ENSMUST00000119115(transcript)|intact:EBI-301496(isoform-parent)	refseq:NP_033183.1|dip:DIP-869N|ensembl:ENSMUSG00000033352(gene)|ensembl:ENSMUST00000046963(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007254"(JNK cascade)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008545"(JUN kinase kinase activity)|go:"GO:0009611"(response to wounding)|go:"GO:0030424"(axon)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0034393"(positive regulation of smooth muscle cell apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0072709"(cellular response to sorbitol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000672"(negative regulation of motor neuron apoptotic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P47809|reactome:R-MMU-2559580|reactome:R-MMU-2871796|reactome:R-MMU-450321	-	-	-	figure legend:Fig. 4, 5A,B|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2014/06/11	2014/10/16	rogid:Gw0J1by2qB5lEjidH2opKY1hePk10090	rogid:6v5etIlqj4yLuTNnVlEBVRaMYKg10090	intact-crc:7BD96F2B60F54ABD|rigid:S5qLhhK6joFn6yrfO4ObUcBGn80	false	his tag:n-n|s tag:n-n|necessary binding region:1054-1305	flag tag:n-n|N-phosphorylated residue:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9ESN9-2	uniprotkb:P47809	intact:EBI-9549291|ensembl:ENSMUSP00000112955	intact:EBI-447934|ensembl:ENSMUSP00000041282	psi-mi:q9esn9-2(display_long)|uniprotkb:Mapk8ip3(gene name)|psi-mi:Mapk8ip3(display_short)|uniprotkb:Jip3(gene name synonym)|uniprotkb:Jsap1(gene name synonym)|uniprotkb:Syd2(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 3(gene name synonym)|uniprotkb:JNK/SAPK-associated protein 1(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 3(gene name synonym)|uniprotkb:Sunday driver 2(gene name synonym)	psi-mi:mp2k4_mouse(display_long)|uniprotkb:MAPK/ERK kinase 4(gene name synonym)|uniprotkb:JNK-activating kinase 1(gene name synonym)|uniprotkb:C-JUN N-terminal kinase kinase 1(gene name synonym)|uniprotkb:SAPK/ERK kinase 1(gene name synonym)|uniprotkb:Map2k4(gene name)|psi-mi:Map2k4(display_short)|uniprotkb:Jnkk1(gene name synonym)|uniprotkb:Prkmk4(gene name synonym)|uniprotkb:Sek1(gene name synonym)|uniprotkb:Serk1(gene name synonym)|uniprotkb:Skk1(gene name synonym)|uniprotkb:Mkk4(gene name synonym)|uniprotkb:Mek4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ito et al. (1999)	imex:IM-22967|pubmed:10523642	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-9550942|imex:IM-22967-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0941"(competitor)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000024163(gene)|ensembl:ENSMUST00000119115(transcript)|intact:EBI-301496(isoform-parent)	refseq:NP_033183.1|dip:DIP-869N|ensembl:ENSMUSG00000033352(gene)|ensembl:ENSMUST00000046963(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007254"(JNK cascade)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008545"(JUN kinase kinase activity)|go:"GO:0009611"(response to wounding)|go:"GO:0030424"(axon)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0034393"(positive regulation of smooth muscle cell apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0072709"(cellular response to sorbitol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000672"(negative regulation of motor neuron apoptotic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P47809|reactome:R-MMU-2559580|reactome:R-MMU-2871796|reactome:R-MMU-450321	-	-	-	figure legend:Fig. 5B|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2014/06/11	2014/10/16	rogid:Gw0J1by2qB5lEjidH2opKY1hePk10090	rogid:6v5etIlqj4yLuTNnVlEBVRaMYKg10090	intact-crc:B61B0C487798AABB|rigid:wFtqgayYNHMrDLwNEoMlbt9CTaU	false	his tag:n-n|s tag:n-n	flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9ESN9-2	uniprotkb:P31938	intact:EBI-9549291|ensembl:ENSMUSP00000112955	intact:EBI-298860|ensembl:ENSMUSP00000005066	psi-mi:q9esn9-2(display_long)|uniprotkb:Mapk8ip3(gene name)|psi-mi:Mapk8ip3(display_short)|uniprotkb:Jip3(gene name synonym)|uniprotkb:Jsap1(gene name synonym)|uniprotkb:Syd2(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 3(gene name synonym)|uniprotkb:JNK/SAPK-associated protein 1(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 3(gene name synonym)|uniprotkb:Sunday driver 2(gene name synonym)	psi-mi:mp2k1_mouse(display_long)|uniprotkb:Map2k1(gene name)|psi-mi:Map2k1(display_short)|uniprotkb:Mek1(gene name synonym)|uniprotkb:Prkmk1(gene name synonym)|uniprotkb:ERK activator kinase 1(gene name synonym)|uniprotkb:MAPK/ERK kinase 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ito et al. (1999)	imex:IM-22967|pubmed:10523642	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-9550942|imex:IM-22967-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000024163(gene)|ensembl:ENSMUST00000119115(transcript)|intact:EBI-301496(isoform-parent)	ensembl:ENSMUSG00000004936(gene)|ensembl:ENSMUST00000005066(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003056"(regulation of vascular associated smooth muscle contraction)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007507"(heart development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021697"(cerebellar cortex formation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043204"(perikaryon)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032402"(melanosome transport)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034111"(negative regulation of homotypic cell-cell adhesion)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048313"(Golgi inheritance)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048538"(thymus development)|go:"GO:0048678"(response to axon injury)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060324"(face development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060440"(trachea formation)|go:"GO:0060502"(epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060674"(placenta blood vessel development)|go:"GO:0060711"(labyrinthine layer development)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0090398"(cellular senescence)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-MMU-110056|reactome:R-MMU-170968|reactome:R-MMU-445144|reactome:R-MMU-5673000|reactome:R-MMU-5674135|reactome:R-MMU-5674499|refseq:NP_032953.1|dip:DIP-467N	-	-	-	figure legend:Fig. 5B|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2014/06/11	2014/10/16	rogid:Gw0J1by2qB5lEjidH2opKY1hePk10090	rogid:OOj1juW9l4rnEH/W3CjXWZFKMvw10090	intact-crc:B61B0C487798AABB|rigid:wFtqgayYNHMrDLwNEoMlbt9CTaU	false	his tag:n-n|s tag:n-n	myc tag:?-?|phosphorylated residue:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9ESN9-2	uniprotkb:P47809	intact:EBI-9549291|ensembl:ENSMUSP00000112955	intact:EBI-447934|ensembl:ENSMUSP00000041282	psi-mi:q9esn9-2(display_long)|uniprotkb:Mapk8ip3(gene name)|psi-mi:Mapk8ip3(display_short)|uniprotkb:Jip3(gene name synonym)|uniprotkb:Jsap1(gene name synonym)|uniprotkb:Syd2(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 3(gene name synonym)|uniprotkb:JNK/SAPK-associated protein 1(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 3(gene name synonym)|uniprotkb:Sunday driver 2(gene name synonym)	psi-mi:mp2k4_mouse(display_long)|uniprotkb:MAPK/ERK kinase 4(gene name synonym)|uniprotkb:JNK-activating kinase 1(gene name synonym)|uniprotkb:C-JUN N-terminal kinase kinase 1(gene name synonym)|uniprotkb:SAPK/ERK kinase 1(gene name synonym)|uniprotkb:Map2k4(gene name)|psi-mi:Map2k4(display_short)|uniprotkb:Jnkk1(gene name synonym)|uniprotkb:Prkmk4(gene name synonym)|uniprotkb:Sek1(gene name synonym)|uniprotkb:Serk1(gene name synonym)|uniprotkb:Skk1(gene name synonym)|uniprotkb:Mkk4(gene name synonym)|uniprotkb:Mek4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ito et al. (1999)	imex:IM-22967|pubmed:10523642	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-9636906|imex:IM-22967-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000024163(gene)|ensembl:ENSMUST00000119115(transcript)|intact:EBI-301496(isoform-parent)	refseq:NP_033183.1|dip:DIP-869N|ensembl:ENSMUSG00000033352(gene)|ensembl:ENSMUST00000046963(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007254"(JNK cascade)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008545"(JUN kinase kinase activity)|go:"GO:0009611"(response to wounding)|go:"GO:0030424"(axon)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0034393"(positive regulation of smooth muscle cell apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0072709"(cellular response to sorbitol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000672"(negative regulation of motor neuron apoptotic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P47809|reactome:R-MMU-2559580|reactome:R-MMU-2871796|reactome:R-MMU-450321	-	-	-	figure legend:Fig. 5B|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2014/06/11	2014/10/16	rogid:Gw0J1by2qB5lEjidH2opKY1hePk10090	rogid:6v5etIlqj4yLuTNnVlEBVRaMYKg10090	intact-crc:AC4E699A6A00CE52|rigid:wFtqgayYNHMrDLwNEoMlbt9CTaU	false	s tag:n-n|his tag:n-n	flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9ESN9-2	uniprotkb:P31938	intact:EBI-9549291|ensembl:ENSMUSP00000112955	intact:EBI-298860|ensembl:ENSMUSP00000005066	psi-mi:q9esn9-2(display_long)|uniprotkb:Mapk8ip3(gene name)|psi-mi:Mapk8ip3(display_short)|uniprotkb:Jip3(gene name synonym)|uniprotkb:Jsap1(gene name synonym)|uniprotkb:Syd2(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 3(gene name synonym)|uniprotkb:JNK/SAPK-associated protein 1(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 3(gene name synonym)|uniprotkb:Sunday driver 2(gene name synonym)	psi-mi:mp2k1_mouse(display_long)|uniprotkb:Map2k1(gene name)|psi-mi:Map2k1(display_short)|uniprotkb:Mek1(gene name synonym)|uniprotkb:Prkmk1(gene name synonym)|uniprotkb:ERK activator kinase 1(gene name synonym)|uniprotkb:MAPK/ERK kinase 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ito et al. (1999)	imex:IM-22967|pubmed:10523642	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-9636906|imex:IM-22967-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0941"(competitor)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000024163(gene)|ensembl:ENSMUST00000119115(transcript)|intact:EBI-301496(isoform-parent)	ensembl:ENSMUSG00000004936(gene)|ensembl:ENSMUST00000005066(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003056"(regulation of vascular associated smooth muscle contraction)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007507"(heart development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021697"(cerebellar cortex formation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043204"(perikaryon)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032402"(melanosome transport)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034111"(negative regulation of homotypic cell-cell adhesion)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048313"(Golgi inheritance)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048538"(thymus development)|go:"GO:0048678"(response to axon injury)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060324"(face development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060440"(trachea formation)|go:"GO:0060502"(epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060674"(placenta blood vessel development)|go:"GO:0060711"(labyrinthine layer development)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0090398"(cellular senescence)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-MMU-110056|reactome:R-MMU-170968|reactome:R-MMU-445144|reactome:R-MMU-5673000|reactome:R-MMU-5674135|reactome:R-MMU-5674499|refseq:NP_032953.1|dip:DIP-467N	-	-	-	figure legend:Fig. 5B|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2014/06/11	2014/10/16	rogid:Gw0J1by2qB5lEjidH2opKY1hePk10090	rogid:OOj1juW9l4rnEH/W3CjXWZFKMvw10090	intact-crc:AC4E699A6A00CE52|rigid:wFtqgayYNHMrDLwNEoMlbt9CTaU	false	s tag:n-n|his tag:n-n	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9ESN9-2	uniprotkb:P31938	intact:EBI-9549291|ensembl:ENSMUSP00000112955	intact:EBI-298860|ensembl:ENSMUSP00000005066	psi-mi:q9esn9-2(display_long)|uniprotkb:Mapk8ip3(gene name)|psi-mi:Mapk8ip3(display_short)|uniprotkb:Jip3(gene name synonym)|uniprotkb:Jsap1(gene name synonym)|uniprotkb:Syd2(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 3(gene name synonym)|uniprotkb:JNK/SAPK-associated protein 1(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 3(gene name synonym)|uniprotkb:Sunday driver 2(gene name synonym)	psi-mi:mp2k1_mouse(display_long)|uniprotkb:Map2k1(gene name)|psi-mi:Map2k1(display_short)|uniprotkb:Mek1(gene name synonym)|uniprotkb:Prkmk1(gene name synonym)|uniprotkb:ERK activator kinase 1(gene name synonym)|uniprotkb:MAPK/ERK kinase 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ito et al. (1999)	imex:IM-22967|pubmed:10523642	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-9550849|imex:IM-22967-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000024163(gene)|ensembl:ENSMUST00000119115(transcript)|intact:EBI-301496(isoform-parent)	ensembl:ENSMUSG00000004936(gene)|ensembl:ENSMUST00000005066(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003056"(regulation of vascular associated smooth muscle contraction)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007507"(heart development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021697"(cerebellar cortex formation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043204"(perikaryon)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032402"(melanosome transport)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034111"(negative regulation of homotypic cell-cell adhesion)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048313"(Golgi inheritance)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048538"(thymus development)|go:"GO:0048678"(response to axon injury)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060324"(face development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060440"(trachea formation)|go:"GO:0060502"(epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060674"(placenta blood vessel development)|go:"GO:0060711"(labyrinthine layer development)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0090398"(cellular senescence)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-MMU-110056|reactome:R-MMU-170968|reactome:R-MMU-445144|reactome:R-MMU-5673000|reactome:R-MMU-5674135|reactome:R-MMU-5674499|refseq:NP_032953.1|dip:DIP-467N	-	-	-	figure legend:Fig. 5A|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2014/06/11	2014/10/16	rogid:Gw0J1by2qB5lEjidH2opKY1hePk10090	rogid:OOj1juW9l4rnEH/W3CjXWZFKMvw10090	intact-crc:B4D9CA1A2F2C1820|rigid:b2XLq4Xdz4tbJB31BYW8DSQVfI8	false	s tag:n-n|his tag:n-n	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P53349	uniprotkb:Q9ESN9-2	intact:EBI-447913|uniprotkb:Q60831|uniprotkb:Q9R0U3|uniprotkb:Q9R256	intact:EBI-9549291|ensembl:ENSMUSP00000112955	psi-mi:m3k1_mouse(display_long)|uniprotkb:MAPK/ERK kinase kinase 1(gene name synonym)|uniprotkb:Map3k1(gene name)|psi-mi:Map3k1(display_short)|uniprotkb:Mekk(gene name synonym)|uniprotkb:Mekk1(gene name synonym)	psi-mi:q9esn9-2(display_long)|uniprotkb:Mapk8ip3(gene name)|psi-mi:Mapk8ip3(display_short)|uniprotkb:Jip3(gene name synonym)|uniprotkb:Jsap1(gene name synonym)|uniprotkb:Syd2(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 3(gene name synonym)|uniprotkb:JNK/SAPK-associated protein 1(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 3(gene name synonym)|uniprotkb:Sunday driver 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ito et al. (1999)	imex:IM-22967|pubmed:10523642	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-9550988|imex:IM-22967-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004706"(JUN kinase kinase kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007254"(JNK cascade)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008432"(JUN kinase binding)|dip:DIP-32487N|mint:P53349|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0042060"(wound healing)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR007527(Zinc finger, SWIM-type)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-MMU-166058|reactome:R-MMU-2871796|reactome:R-MMU-975138|reactome:R-MMU-975871|interpro:IPR000719(Protein kinase, core)	ensembl:ENSMUSG00000024163(gene)|ensembl:ENSMUST00000119115(transcript)|intact:EBI-301496(isoform-parent)	-	-	-	figure legend:Fig. 6A, 7A|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2014/06/11	2014/10/16	rogid:DR/c3qeWhJ76oKsNMEVhcUPmpXE10090	rogid:Gw0J1by2qB5lEjidH2opKY1hePk10090	intact-crc:F18C295E1F8435B8|rigid:ReMHdXV415999GQCzxckqr5bqvc	false	sufficient binding region:1-640|flag tag:n-n	his tag:n-n|s tag:n-n|necessary binding region:343-1053	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9ESN9-2	uniprotkb:P53349	intact:EBI-9549291|ensembl:ENSMUSP00000112955	intact:EBI-447913|uniprotkb:Q60831|uniprotkb:Q9R0U3|uniprotkb:Q9R256	psi-mi:q9esn9-2(display_long)|uniprotkb:Mapk8ip3(gene name)|psi-mi:Mapk8ip3(display_short)|uniprotkb:Jip3(gene name synonym)|uniprotkb:Jsap1(gene name synonym)|uniprotkb:Syd2(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 3(gene name synonym)|uniprotkb:JNK/SAPK-associated protein 1(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 3(gene name synonym)|uniprotkb:Sunday driver 2(gene name synonym)	psi-mi:m3k1_mouse(display_long)|uniprotkb:MAPK/ERK kinase kinase 1(gene name synonym)|uniprotkb:Map3k1(gene name)|psi-mi:Map3k1(display_short)|uniprotkb:Mekk(gene name synonym)|uniprotkb:Mekk1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ito et al. (1999)	imex:IM-22967|pubmed:10523642	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-9637077|imex:IM-22967-16	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000024163(gene)|ensembl:ENSMUST00000119115(transcript)|intact:EBI-301496(isoform-parent)	go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004706"(JUN kinase kinase kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007254"(JNK cascade)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008432"(JUN kinase binding)|dip:DIP-32487N|mint:P53349|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0042060"(wound healing)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR007527(Zinc finger, SWIM-type)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-MMU-166058|reactome:R-MMU-2871796|reactome:R-MMU-975138|reactome:R-MMU-975871|interpro:IPR000719(Protein kinase, core)	-	-	-	figure legend:Fig.7B|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2014/06/11	2014/10/16	rogid:Gw0J1by2qB5lEjidH2opKY1hePk10090	rogid:DR/c3qeWhJ76oKsNMEVhcUPmpXE10090	intact-crc:C76226C98FD2B165|rigid:+sDoH8DUUsbItvn1wCfxxzw8vWA	false	s tag:n-n|his tag:n-n	sufficient binding region:1-640|flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9ESN9-2	uniprotkb:P04049	intact:EBI-9549291|ensembl:ENSMUSP00000112955	intact:EBI-365996|uniprotkb:B0LPH8|uniprotkb:Q15278|uniprotkb:Q9UC20|ensembl:ENSP00000251849|uniprotkb:B2R5N3	psi-mi:q9esn9-2(display_long)|uniprotkb:Mapk8ip3(gene name)|psi-mi:Mapk8ip3(display_short)|uniprotkb:Jip3(gene name synonym)|uniprotkb:Jsap1(gene name synonym)|uniprotkb:Syd2(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 3(gene name synonym)|uniprotkb:JNK/SAPK-associated protein 1(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 3(gene name synonym)|uniprotkb:Sunday driver 2(gene name synonym)	psi-mi:raf1_human(display_long)|uniprotkb:RAF1(gene name)|psi-mi:RAF1(display_short)|uniprotkb:RAF(gene name synonym)|uniprotkb:Proto-oncogene c-RAF(gene name synonym)|uniprotkb:Raf-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ito et al. (1999)	imex:IM-22967|pubmed:10523642	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-9637077|imex:IM-22967-16	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000024163(gene)|ensembl:ENSMUST00000119115(transcript)|intact:EBI-301496(isoform-parent)	rcsb pdb:3IQV|rcsb pdb:3KUC|rcsb pdb:3KUD|rcsb pdb:3NKX|rcsb pdb:3O8I|rcsb pdb:3OMV|rcsb pdb:4FJ3|rcsb pdb:4G0N|rcsb pdb:4G3X|rcsb pdb:4IEA|rcsb pdb:4IHL|rcsb pdb:6NTC|rcsb pdb:6NTD|rcsb pdb:6PTS|rcsb pdb:6PTW|rcsb pdb:6VJJ|rcsb pdb:6XGU|rcsb pdb:6XGV|rcsb pdb:6XHA|rcsb pdb:6XHB|rcsb pdb:6XI7|ensembl:ENSG00000132155(gene)|ensembl:ENST00000251849(transcript)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0007507"(heart development)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031143"(pseudopodium)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035773"(insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048538"(thymus development)|go:"GO:0060324"(face development)|go:"GO:0071550"(death-inducing signaling complex assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR003116(Raf-like Ras-binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020454|interpro:IPR029071|mint:P04049|rcsb pdb:1C1Y|rcsb pdb:1FAQ|rcsb pdb:1FAR|rcsb pdb:1GUA|rcsb pdb:1RFA|rcsb pdb:3CU8|rcsb pdb:3IQJ|rcsb pdb:3IQU|rcsb pdb:7JHP|reactome:R-HSA-2672351|reactome:R-HSA-392517|reactome:R-HSA-430116|reactome:R-HSA-5621575|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9660537|refseq:NP_002871.1|refseq:XP_011532276.1|refseq:XP_005265412.1|dip:DIP-1048N	-	-	-	figure legend:Fig.7B|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2014/06/11	2014/10/16	rogid:Gw0J1by2qB5lEjidH2opKY1hePk10090	rogid:1WOAPuzcZdMoq9hyFD/qr4Tz7049606	intact-crc:C76226C98FD2B165|rigid:+sDoH8DUUsbItvn1wCfxxzw8vWA	false	s tag:n-n|his tag:n-n	sufficient binding region:316-648|flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P04049	uniprotkb:Q9ESN9-2	intact:EBI-365996|uniprotkb:B0LPH8|uniprotkb:Q15278|uniprotkb:Q9UC20|ensembl:ENSP00000251849|uniprotkb:B2R5N3	intact:EBI-9549291|ensembl:ENSMUSP00000112955	psi-mi:raf1_human(display_long)|uniprotkb:RAF1(gene name)|psi-mi:RAF1(display_short)|uniprotkb:RAF(gene name synonym)|uniprotkb:Proto-oncogene c-RAF(gene name synonym)|uniprotkb:Raf-1(gene name synonym)	psi-mi:q9esn9-2(display_long)|uniprotkb:Mapk8ip3(gene name)|psi-mi:Mapk8ip3(display_short)|uniprotkb:Jip3(gene name synonym)|uniprotkb:Jsap1(gene name synonym)|uniprotkb:Syd2(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 3(gene name synonym)|uniprotkb:JNK/SAPK-associated protein 1(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 3(gene name synonym)|uniprotkb:Sunday driver 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ito et al. (1999)	imex:IM-22967|pubmed:10523642	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-9551213|imex:IM-22967-14	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:3IQV|rcsb pdb:3KUC|rcsb pdb:3KUD|rcsb pdb:3NKX|rcsb pdb:3O8I|rcsb pdb:3OMV|rcsb pdb:4FJ3|rcsb pdb:4G0N|rcsb pdb:4G3X|rcsb pdb:4IEA|rcsb pdb:4IHL|rcsb pdb:6NTC|rcsb pdb:6NTD|rcsb pdb:6PTS|rcsb pdb:6PTW|rcsb pdb:6VJJ|rcsb pdb:6XGU|rcsb pdb:6XGV|rcsb pdb:6XHA|rcsb pdb:6XHB|rcsb pdb:6XI7|ensembl:ENSG00000132155(gene)|ensembl:ENST00000251849(transcript)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0007507"(heart development)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031143"(pseudopodium)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035773"(insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048538"(thymus development)|go:"GO:0060324"(face development)|go:"GO:0071550"(death-inducing signaling complex assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR003116(Raf-like Ras-binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020454|interpro:IPR029071|mint:P04049|rcsb pdb:1C1Y|rcsb pdb:1FAQ|rcsb pdb:1FAR|rcsb pdb:1GUA|rcsb pdb:1RFA|rcsb pdb:3CU8|rcsb pdb:3IQJ|rcsb pdb:3IQU|rcsb pdb:7JHP|reactome:R-HSA-2672351|reactome:R-HSA-392517|reactome:R-HSA-430116|reactome:R-HSA-5621575|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9660537|refseq:NP_002871.1|refseq:XP_011532276.1|refseq:XP_005265412.1|dip:DIP-1048N	ensembl:ENSMUSG00000024163(gene)|ensembl:ENSMUST00000119115(transcript)|intact:EBI-301496(isoform-parent)	-	-	-	figure legend:Fig.7A|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2014/06/11	2014/10/16	rogid:1WOAPuzcZdMoq9hyFD/qr4Tz7049606	rogid:Gw0J1by2qB5lEjidH2opKY1hePk10090	intact-crc:591C58C6BCFB77D4|rigid:gHZPks7pW3BG0CusxrjzF/cpqRM	false	flag tag:n-n|sufficient binding region:316-648	his tag:n-n|s tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9ESN9-2	uniprotkb:Q61831	intact:EBI-9549291|ensembl:ENSMUSP00000112955	intact:EBI-400741|uniprotkb:Q9R0U6	psi-mi:q9esn9-2(display_long)|uniprotkb:Mapk8ip3(gene name)|psi-mi:Mapk8ip3(display_short)|uniprotkb:Jip3(gene name synonym)|uniprotkb:Jsap1(gene name synonym)|uniprotkb:Syd2(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 3(gene name synonym)|uniprotkb:JNK/SAPK-associated protein 1(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 3(gene name synonym)|uniprotkb:Sunday driver 2(gene name synonym)	psi-mi:mk10_mouse(display_long)|uniprotkb:Mapk10(gene name)|psi-mi:Mapk10(display_short)|uniprotkb:Jnk3(gene name synonym)|uniprotkb:Prkm10(gene name synonym)|uniprotkb:Serk2(gene name synonym)|uniprotkb:Stress-activated protein kinase JNK3(gene name synonym)|uniprotkb:c-Jun N-terminal kinase 3(gene name synonym)|uniprotkb:MAP kinase p49 3F12(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ito et al. (1999)	imex:IM-22967|pubmed:10523642	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-9549890|imex:IM-22967-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000024163(gene)|ensembl:ENSMUST00000119115(transcript)|intact:EBI-301496(isoform-parent)	interpro:IPR008351(JNK MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|refseq:XP_017176379.1|refseq:NP_001297615.1|refseq:XP_017176380.1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004705"(JUN kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007254"(JNK cascade)|go:"GO:0007258"(JUN phosphorylation)|go:"GO:0009416"(response to light stimulus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0098969"(neurotransmitter receptor transport to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|reactome:R-MMU-2559580|reactome:R-MMU-2871796|reactome:R-MMU-450321|reactome:R-MMU-450341	-	-	-	figure legend:Fig. 2B|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/06/11	2014/10/16	rogid:Gw0J1by2qB5lEjidH2opKY1hePk10090	rogid:5x8VKNSD0AmjnO8BgrewNT2Ypb810090	intact-crc:8E8475AEB2F44BEB|rigid:+17vvqWT5Yd2fSlLeLlD/ZdTSZg	false	his tag:n-n|sufficient binding region:115-233|s tag:n-n|fusion protein:n-n	35s radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q9ESN9-2	uniprotkb:P53349	intact:EBI-9549291|ensembl:ENSMUSP00000112955	intact:EBI-447913|uniprotkb:Q60831|uniprotkb:Q9R0U3|uniprotkb:Q9R256	psi-mi:q9esn9-2(display_long)|uniprotkb:Mapk8ip3(gene name)|psi-mi:Mapk8ip3(display_short)|uniprotkb:Jip3(gene name synonym)|uniprotkb:Jsap1(gene name synonym)|uniprotkb:Syd2(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 3(gene name synonym)|uniprotkb:JNK/SAPK-associated protein 1(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 3(gene name synonym)|uniprotkb:Sunday driver 2(gene name synonym)	psi-mi:m3k1_mouse(display_long)|uniprotkb:MAPK/ERK kinase kinase 1(gene name synonym)|uniprotkb:Map3k1(gene name)|psi-mi:Map3k1(display_short)|uniprotkb:Mekk(gene name synonym)|uniprotkb:Mekk1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ito et al. (1999)	imex:IM-22967|pubmed:10523642	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-9551097|imex:IM-22967-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000024163(gene)|ensembl:ENSMUST00000119115(transcript)|intact:EBI-301496(isoform-parent)	go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004706"(JUN kinase kinase kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007254"(JNK cascade)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008432"(JUN kinase binding)|dip:DIP-32487N|mint:P53349|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0042060"(wound healing)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR007527(Zinc finger, SWIM-type)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-MMU-166058|reactome:R-MMU-2871796|reactome:R-MMU-975138|reactome:R-MMU-975871|interpro:IPR000719(Protein kinase, core)	-	-	-	figure legend:Fig. 6B|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/06/11	2014/10/16	rogid:Gw0J1by2qB5lEjidH2opKY1hePk10090	rogid:DR/c3qeWhJ76oKsNMEVhcUPmpXE10090	intact-crc:8486FD77270CE5CB|rigid:ReMHdXV415999GQCzxckqr5bqvc	false	his tag:n-n|s tag:n-n|fusion protein:n-n|sufficient binding region:486-744	35s radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q9ESN9-2	uniprotkb:Q61831	intact:EBI-9549291|ensembl:ENSMUSP00000112955	intact:EBI-400741|uniprotkb:Q9R0U6	psi-mi:q9esn9-2(display_long)|uniprotkb:Mapk8ip3(gene name)|psi-mi:Mapk8ip3(display_short)|uniprotkb:Jip3(gene name synonym)|uniprotkb:Jsap1(gene name synonym)|uniprotkb:Syd2(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 3(gene name synonym)|uniprotkb:JNK/SAPK-associated protein 1(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 3(gene name synonym)|uniprotkb:Sunday driver 2(gene name synonym)	psi-mi:mk10_mouse(display_long)|uniprotkb:Mapk10(gene name)|psi-mi:Mapk10(display_short)|uniprotkb:Jnk3(gene name synonym)|uniprotkb:Prkm10(gene name synonym)|uniprotkb:Serk2(gene name synonym)|uniprotkb:Stress-activated protein kinase JNK3(gene name synonym)|uniprotkb:c-Jun N-terminal kinase 3(gene name synonym)|uniprotkb:MAP kinase p49 3F12(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Ito et al. (1999)	imex:IM-22967|pubmed:10523642	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-9550243|imex:IM-22967-7	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000024163(gene)|ensembl:ENSMUST00000119115(transcript)|intact:EBI-301496(isoform-parent)	interpro:IPR008351(JNK MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|refseq:XP_017176379.1|refseq:NP_001297615.1|refseq:XP_017176380.1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004705"(JUN kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007254"(JNK cascade)|go:"GO:0007258"(JUN phosphorylation)|go:"GO:0009416"(response to light stimulus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0098969"(neurotransmitter receptor transport to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|reactome:R-MMU-2559580|reactome:R-MMU-2871796|reactome:R-MMU-450321|reactome:R-MMU-450341	go:"GO:0006468"(protein phosphorylation)|go:"GO:0004672"(protein kinase activity)	-	-	figure legend:Fig. 3A|resulting-ptm:Q9ESN9-2 thr-234 O-phospho-L-threonine|resulting-ptm:Q9ESN9-2 thr-244 O-phospho-L-threonine|resulting-ptm:Q9ESN9-2 thr-255 O-phospho-L-threonine|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/06/11	2014/10/16	rogid:Gw0J1by2qB5lEjidH2opKY1hePk10090	rogid:5x8VKNSD0AmjnO8BgrewNT2Ypb810090	intact-crc:0D0487FB66476B99|rigid:+17vvqWT5Yd2fSlLeLlD/ZdTSZg	false	sufficient binding region:115-274|fusion protein:n-n|his tag:n-n|s tag:n-n|mutation decreasing interaction rate:234-234,244-244,255-255	flag tag:n-n|N-phosphorylated residue:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q61831	uniprotkb:Q9ESN9-2	intact:EBI-400741|uniprotkb:Q9R0U6	intact:EBI-9549291|ensembl:ENSMUSP00000112955	psi-mi:mk10_mouse(display_long)|uniprotkb:Mapk10(gene name)|psi-mi:Mapk10(display_short)|uniprotkb:Jnk3(gene name synonym)|uniprotkb:Prkm10(gene name synonym)|uniprotkb:Serk2(gene name synonym)|uniprotkb:Stress-activated protein kinase JNK3(gene name synonym)|uniprotkb:c-Jun N-terminal kinase 3(gene name synonym)|uniprotkb:MAP kinase p49 3F12(gene name synonym)	psi-mi:q9esn9-2(display_long)|uniprotkb:Mapk8ip3(gene name)|psi-mi:Mapk8ip3(display_short)|uniprotkb:Jip3(gene name synonym)|uniprotkb:Jsap1(gene name synonym)|uniprotkb:Syd2(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 3(gene name synonym)|uniprotkb:JNK/SAPK-associated protein 1(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 3(gene name synonym)|uniprotkb:Sunday driver 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ito et al. (1999)	imex:IM-22967|pubmed:10523642	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-9550593|imex:IM-22967-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR008351(JNK MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|refseq:XP_017176379.1|refseq:NP_001297615.1|refseq:XP_017176380.1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004705"(JUN kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007254"(JNK cascade)|go:"GO:0007258"(JUN phosphorylation)|go:"GO:0009416"(response to light stimulus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0098969"(neurotransmitter receptor transport to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|reactome:R-MMU-2559580|reactome:R-MMU-2871796|reactome:R-MMU-450321|reactome:R-MMU-450341	ensembl:ENSMUSG00000024163(gene)|ensembl:ENSMUST00000119115(transcript)|intact:EBI-301496(isoform-parent)	-	-	-	figure legend:Fig. 3B|comment:"When MEKK (1169-1488) is co-transfected in COS 7 cells together with Flag-JNK3,  the interaction between JNK3 and JSAP1 did not happened."|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/06/11	2014/10/16	rogid:5x8VKNSD0AmjnO8BgrewNT2Ypb810090	rogid:Gw0J1by2qB5lEjidH2opKY1hePk10090	intact-crc:1F809F1298B19A6E|rigid:+17vvqWT5Yd2fSlLeLlD/ZdTSZg	false	flag tag:n-n	s tag:n-n|sufficient binding region:115-274|his tag:n-n|fusion protein:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P47809	uniprotkb:P53349	intact:EBI-447934|ensembl:ENSMUSP00000041282	intact:EBI-447913|uniprotkb:Q60831|uniprotkb:Q9R0U3|uniprotkb:Q9R256	psi-mi:mp2k4_mouse(display_long)|uniprotkb:MAPK/ERK kinase 4(gene name synonym)|uniprotkb:JNK-activating kinase 1(gene name synonym)|uniprotkb:C-JUN N-terminal kinase kinase 1(gene name synonym)|uniprotkb:SAPK/ERK kinase 1(gene name synonym)|uniprotkb:Map2k4(gene name)|psi-mi:Map2k4(display_short)|uniprotkb:Jnkk1(gene name synonym)|uniprotkb:Prkmk4(gene name synonym)|uniprotkb:Sek1(gene name synonym)|uniprotkb:Serk1(gene name synonym)|uniprotkb:Skk1(gene name synonym)|uniprotkb:Mkk4(gene name synonym)|uniprotkb:Mek4(gene name synonym)	psi-mi:m3k1_mouse(display_long)|uniprotkb:MAPK/ERK kinase kinase 1(gene name synonym)|uniprotkb:Map3k1(gene name)|psi-mi:Map3k1(display_short)|uniprotkb:Mekk(gene name synonym)|uniprotkb:Mekk1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ito et al. (1999)	imex:IM-22967|pubmed:10523642	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-9551180|imex:IM-22967-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033183.1|dip:DIP-869N|ensembl:ENSMUSG00000033352(gene)|ensembl:ENSMUST00000046963(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007254"(JNK cascade)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008545"(JUN kinase kinase activity)|go:"GO:0009611"(response to wounding)|go:"GO:0030424"(axon)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0034393"(positive regulation of smooth muscle cell apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0072709"(cellular response to sorbitol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000672"(negative regulation of motor neuron apoptotic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P47809|reactome:R-MMU-2559580|reactome:R-MMU-2871796|reactome:R-MMU-450321	go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004706"(JUN kinase kinase kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007254"(JNK cascade)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008432"(JUN kinase binding)|dip:DIP-32487N|mint:P53349|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0042060"(wound healing)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR007527(Zinc finger, SWIM-type)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-MMU-166058|reactome:R-MMU-2871796|reactome:R-MMU-975138|reactome:R-MMU-975871|interpro:IPR000719(Protein kinase, core)	-	-	-	figure legend:Fig.6C|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/06/11	2014/10/16	rogid:6v5etIlqj4yLuTNnVlEBVRaMYKg10090	rogid:DR/c3qeWhJ76oKsNMEVhcUPmpXE10090	intact-crc:43832F4EB32B0EBE|rigid:CKU1cs11YK2esXTFTJdjUAL+Gag	false	his tag:?-?|s tag:?-?|fusion protein:?-?	sufficient binding region:1169-1488|flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)