#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P49789	uniprotkb:P49789	intact:EBI-741760|uniprotkb:Q6IU12|ensembl:ENSP00000417480|ensembl:ENSP00000417557|ensembl:ENSP00000418582|uniprotkb:A2IAS9|uniprotkb:A2IAT0|uniprotkb:A2IAT6|uniprotkb:A8K1A9|uniprotkb:Q45QG9	intact:EBI-741760|uniprotkb:Q6IU12|ensembl:ENSP00000417480|ensembl:ENSP00000417557|ensembl:ENSP00000418582|uniprotkb:A2IAS9|uniprotkb:A2IAT0|uniprotkb:A2IAT6|uniprotkb:A8K1A9|uniprotkb:Q45QG9	psi-mi:fhit_human(display_long)|uniprotkb:Diadenosine 5',5'''-P1,P3-triphosphate hydrolase(gene name synonym)|uniprotkb:Dinucleosidetriphosphatase(gene name synonym)|uniprotkb:AP3A hydrolase(gene name synonym)|uniprotkb:Fragile histidine triad protein(gene name synonym)|uniprotkb:FHIT(gene name)|psi-mi:FHIT(display_short)|uniprotkb:Adenosine 5'-monophosphoramidase FHIT(gene name synonym)|uniprotkb:Adenylylsulfatase(gene name synonym)|uniprotkb:Adenylylsulfate-ammonia adenylyltransferase(gene name synonym)	psi-mi:fhit_human(display_long)|uniprotkb:Diadenosine 5',5'''-P1,P3-triphosphate hydrolase(gene name synonym)|uniprotkb:Dinucleosidetriphosphatase(gene name synonym)|uniprotkb:AP3A hydrolase(gene name synonym)|uniprotkb:Fragile histidine triad protein(gene name synonym)|uniprotkb:FHIT(gene name)|psi-mi:FHIT(display_short)|uniprotkb:Adenosine 5'-monophosphoramidase FHIT(gene name synonym)|uniprotkb:Adenylylsulfatase(gene name synonym)|uniprotkb:Adenylylsulfate-ammonia adenylyltransferase(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Lima et al. (1997)	pubmed:9261067|imex:IM-18697	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6551668|imex:IM-18697-1|pdbe:2fit|pdbe:3fit|pdbe:1fit	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001159715.1|refseq:NP_002003.1|ensembl:ENSG00000189283(gene)|ensembl:ENST00000468189(transcript)|ensembl:ENST00000476844(transcript)|ensembl:ENST00000492590(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006163"(purine nucleotide metabolic process)|go:"GO:0015964"(diadenosine triphosphate catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0047710"("bis(5'-adenosyl)-triphosphatase activity")|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|interpro:IPR001310("Histidine triad (HIT) protein")|interpro:IPR011146(Histidine triad-like motif)|interpro:IPR019808|interpro:IPR036265|interpro:IPR039383|rcsb pdb:1FHI|rcsb pdb:1FIT|rcsb pdb:2FHI|rcsb pdb:2FIT|rcsb pdb:3FIT|rcsb pdb:4FIT|rcsb pdb:5FIT|rcsb pdb:6FIT|refseq:NP_001307828.1|refseq:NP_001307829.1|dip:DIP-29947N	refseq:NP_001159715.1|refseq:NP_002003.1|ensembl:ENSG00000189283(gene)|ensembl:ENST00000468189(transcript)|ensembl:ENST00000476844(transcript)|ensembl:ENST00000492590(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006163"(purine nucleotide metabolic process)|go:"GO:0015964"(diadenosine triphosphate catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0047710"("bis(5'-adenosyl)-triphosphatase activity")|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|interpro:IPR001310("Histidine triad (HIT) protein")|interpro:IPR011146(Histidine triad-like motif)|interpro:IPR019808|interpro:IPR036265|interpro:IPR039383|rcsb pdb:1FHI|rcsb pdb:1FIT|rcsb pdb:2FHI|rcsb pdb:2FIT|rcsb pdb:3FIT|rcsb pdb:4FIT|rcsb pdb:5FIT|rcsb pdb:6FIT|refseq:NP_001307828.1|refseq:NP_001307829.1|dip:DIP-29947N	-	-	-	3d-resolution:1.85 A for 1FIT  1.90 A for 2FIT  2.40 A for 3FIT|3d-r-factors:"R-factor: 0.202 R-free: 0.225 for 1FIT; R-factor: 0.222 R-free: 0.249 for 2FIT; R-factor: 0.201 R-free: 0.249 for 3FIT"|figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/02/25	2014/10/16	rogid:HP0fEbM1naJPi0XrKdkagXZPF0E9606	rogid:HP0fEbM1naJPi0XrKdkagXZPF0E9606	intact-crc:CFD6960E4F065190|rigid:/LglkaQYi2QFyMIOlLI8Jj+3N1I	false	-	-	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)