#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q12809	uniprotkb:Q12809	intact:EBI-720643|uniprotkb:O75418|uniprotkb:O75680|uniprotkb:Q9BT72|uniprotkb:Q9BUT7|uniprotkb:Q9H3P0|uniprotkb:A5H1P7|uniprotkb:D3DX04|uniprotkb:C4PFH9|uniprotkb:Q708S9|ensembl:ENSP00000262186	intact:EBI-720643|uniprotkb:O75418|uniprotkb:O75680|uniprotkb:Q9BT72|uniprotkb:Q9BUT7|uniprotkb:Q9H3P0|uniprotkb:A5H1P7|uniprotkb:D3DX04|uniprotkb:C4PFH9|uniprotkb:Q708S9|ensembl:ENSP00000262186	psi-mi:kcnh2_human(display_long)|uniprotkb:Voltage-gated potassium channel subunit Kv11.1(gene name synonym)|uniprotkb:Ether-a-go-go-related gene potassium channel 1(gene name synonym)|uniprotkb:Eag homolog(gene name synonym)|uniprotkb:KCNH2(gene name)|psi-mi:KCNH2(display_short)|uniprotkb:ERG(gene name synonym)|uniprotkb:ERG1(gene name synonym)|uniprotkb:HERG(gene name synonym)	psi-mi:kcnh2_human(display_long)|uniprotkb:Voltage-gated potassium channel subunit Kv11.1(gene name synonym)|uniprotkb:Ether-a-go-go-related gene potassium channel 1(gene name synonym)|uniprotkb:Eag homolog(gene name synonym)|uniprotkb:KCNH2(gene name)|psi-mi:KCNH2(display_short)|uniprotkb:ERG(gene name synonym)|uniprotkb:ERG1(gene name synonym)|uniprotkb:HERG(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Li et al. (1997)	pubmed:8995352|imex:IM-22141	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-6919966|imex:IM-22141-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000229.1|refseq:NP_001191727.1|refseq:NP_742053.1|refseq:NP_742054.1|dip:DIP-48929N|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035690"|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:1902937"(inward rectifier potassium channel complex)|go:"GO:1903765"(negative regulation of potassium ion export across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000014(PAS)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR001610(PAC motif)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR003967(Potassium channel, voltage-dependent, ERG)|interpro:IPR005821(Ion transport)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018490|interpro:IPR035965|rcsb pdb:1BYW|rcsb pdb:1UJL|rcsb pdb:2L0W|rcsb pdb:2L1M|rcsb pdb:2L4R|rcsb pdb:2LE7|rcsb pdb:2N7G|rcsb pdb:4HP9|rcsb pdb:4HQA|rcsb pdb:5VA1|rcsb pdb:5VA2|rcsb pdb:5VA3|rcsb pdb:6SYG|ensembl:ENSG00000055118(gene)|ensembl:ENST00000262186(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003064"(regulation of heart rate by hormone)|reactome:R-HSA-1296072|reactome:R-HSA-5576890	refseq:NP_000229.1|refseq:NP_001191727.1|refseq:NP_742053.1|refseq:NP_742054.1|dip:DIP-48929N|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035690"|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:1902937"(inward rectifier potassium channel complex)|go:"GO:1903765"(negative regulation of potassium ion export across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000014(PAS)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR001610(PAC motif)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR003967(Potassium channel, voltage-dependent, ERG)|interpro:IPR005821(Ion transport)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018490|interpro:IPR035965|rcsb pdb:1BYW|rcsb pdb:1UJL|rcsb pdb:2L0W|rcsb pdb:2L1M|rcsb pdb:2L4R|rcsb pdb:2LE7|rcsb pdb:2N7G|rcsb pdb:4HP9|rcsb pdb:4HQA|rcsb pdb:5VA1|rcsb pdb:5VA2|rcsb pdb:5VA3|rcsb pdb:6SYG|ensembl:ENSG00000055118(gene)|ensembl:ENST00000262186(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003064"(regulation of heart rate by hormone)|reactome:R-HSA-1296072|reactome:R-HSA-5576890	-	-	-	figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/07/17	2014/10/16	rogid:GgrMfHJ+Gzu6yqgwiNxcMoDKbuY9606	rogid:GgrMfHJ+Gzu6yqgwiNxcMoDKbuY9606	intact-crc:204A39BBA4D466ED|rigid:7nSv9PMyPToTOK/IXwPIAYOqDrE	false	sufficient binding region:1-135(IPR000014)|glutathione s tranferase tag:?-?(IPR000014)	sufficient binding region:1-135(IPR000014)|glutathione s tranferase tag:?-?(IPR000014)	2	0	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q12809	uniprotkb:Q12809	intact:EBI-720643|uniprotkb:O75418|uniprotkb:O75680|uniprotkb:Q9BT72|uniprotkb:Q9BUT7|uniprotkb:Q9H3P0|uniprotkb:A5H1P7|uniprotkb:D3DX04|uniprotkb:C4PFH9|uniprotkb:Q708S9|ensembl:ENSP00000262186	intact:EBI-720643|uniprotkb:O75418|uniprotkb:O75680|uniprotkb:Q9BT72|uniprotkb:Q9BUT7|uniprotkb:Q9H3P0|uniprotkb:A5H1P7|uniprotkb:D3DX04|uniprotkb:C4PFH9|uniprotkb:Q708S9|ensembl:ENSP00000262186	psi-mi:kcnh2_human(display_long)|uniprotkb:Voltage-gated potassium channel subunit Kv11.1(gene name synonym)|uniprotkb:Ether-a-go-go-related gene potassium channel 1(gene name synonym)|uniprotkb:Eag homolog(gene name synonym)|uniprotkb:KCNH2(gene name)|psi-mi:KCNH2(display_short)|uniprotkb:ERG(gene name synonym)|uniprotkb:ERG1(gene name synonym)|uniprotkb:HERG(gene name synonym)	psi-mi:kcnh2_human(display_long)|uniprotkb:Voltage-gated potassium channel subunit Kv11.1(gene name synonym)|uniprotkb:Ether-a-go-go-related gene potassium channel 1(gene name synonym)|uniprotkb:Eag homolog(gene name synonym)|uniprotkb:KCNH2(gene name)|psi-mi:KCNH2(display_short)|uniprotkb:ERG(gene name synonym)|uniprotkb:ERG1(gene name synonym)|uniprotkb:HERG(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Li et al. (1997)	pubmed:8995352|imex:IM-22141	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-6896457|imex:IM-22141-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000229.1|refseq:NP_001191727.1|refseq:NP_742053.1|refseq:NP_742054.1|dip:DIP-48929N|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035690"|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:1902937"(inward rectifier potassium channel complex)|go:"GO:1903765"(negative regulation of potassium ion export across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000014(PAS)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR001610(PAC motif)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR003967(Potassium channel, voltage-dependent, ERG)|interpro:IPR005821(Ion transport)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018490|interpro:IPR035965|rcsb pdb:1BYW|rcsb pdb:1UJL|rcsb pdb:2L0W|rcsb pdb:2L1M|rcsb pdb:2L4R|rcsb pdb:2LE7|rcsb pdb:2N7G|rcsb pdb:4HP9|rcsb pdb:4HQA|rcsb pdb:5VA1|rcsb pdb:5VA2|rcsb pdb:5VA3|rcsb pdb:6SYG|ensembl:ENSG00000055118(gene)|ensembl:ENST00000262186(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003064"(regulation of heart rate by hormone)|reactome:R-HSA-1296072|reactome:R-HSA-5576890	refseq:NP_000229.1|refseq:NP_001191727.1|refseq:NP_742053.1|refseq:NP_742054.1|dip:DIP-48929N|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035690"|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:1902937"(inward rectifier potassium channel complex)|go:"GO:1903765"(negative regulation of potassium ion export across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000014(PAS)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR001610(PAC motif)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR003967(Potassium channel, voltage-dependent, ERG)|interpro:IPR005821(Ion transport)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018490|interpro:IPR035965|rcsb pdb:1BYW|rcsb pdb:1UJL|rcsb pdb:2L0W|rcsb pdb:2L1M|rcsb pdb:2L4R|rcsb pdb:2LE7|rcsb pdb:2N7G|rcsb pdb:4HP9|rcsb pdb:4HQA|rcsb pdb:5VA1|rcsb pdb:5VA2|rcsb pdb:5VA3|rcsb pdb:6SYG|ensembl:ENSG00000055118(gene)|ensembl:ENST00000262186(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003064"(regulation of heart rate by hormone)|reactome:R-HSA-1296072|reactome:R-HSA-5576890	-	-	-	figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/07/17	2014/10/16	rogid:GgrMfHJ+Gzu6yqgwiNxcMoDKbuY9606	rogid:GgrMfHJ+Gzu6yqgwiNxcMoDKbuY9606	intact-crc:15AE013863AAE40A|rigid:7nSv9PMyPToTOK/IXwPIAYOqDrE	false	glutathione s tranferase tag:?-?|sufficient binding region:1-135(IPR000014)	glutathione s tranferase tag:?-?|sufficient binding region:1-135(IPR000014)	4	0	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q12809	uniprotkb:Q12809	intact:EBI-720643|uniprotkb:O75418|uniprotkb:O75680|uniprotkb:Q9BT72|uniprotkb:Q9BUT7|uniprotkb:Q9H3P0|uniprotkb:A5H1P7|uniprotkb:D3DX04|uniprotkb:C4PFH9|uniprotkb:Q708S9|ensembl:ENSP00000262186	intact:EBI-720643|uniprotkb:O75418|uniprotkb:O75680|uniprotkb:Q9BT72|uniprotkb:Q9BUT7|uniprotkb:Q9H3P0|uniprotkb:A5H1P7|uniprotkb:D3DX04|uniprotkb:C4PFH9|uniprotkb:Q708S9|ensembl:ENSP00000262186	psi-mi:kcnh2_human(display_long)|uniprotkb:Voltage-gated potassium channel subunit Kv11.1(gene name synonym)|uniprotkb:Ether-a-go-go-related gene potassium channel 1(gene name synonym)|uniprotkb:Eag homolog(gene name synonym)|uniprotkb:KCNH2(gene name)|psi-mi:KCNH2(display_short)|uniprotkb:ERG(gene name synonym)|uniprotkb:ERG1(gene name synonym)|uniprotkb:HERG(gene name synonym)	psi-mi:kcnh2_human(display_long)|uniprotkb:Voltage-gated potassium channel subunit Kv11.1(gene name synonym)|uniprotkb:Ether-a-go-go-related gene potassium channel 1(gene name synonym)|uniprotkb:Eag homolog(gene name synonym)|uniprotkb:KCNH2(gene name)|psi-mi:KCNH2(display_short)|uniprotkb:ERG(gene name synonym)|uniprotkb:ERG1(gene name synonym)|uniprotkb:HERG(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Li et al. (1997)	pubmed:8995352|imex:IM-22141	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-6920213|imex:IM-22141-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000229.1|refseq:NP_001191727.1|refseq:NP_742053.1|refseq:NP_742054.1|dip:DIP-48929N|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035690"|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:1902937"(inward rectifier potassium channel complex)|go:"GO:1903765"(negative regulation of potassium ion export across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000014(PAS)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR001610(PAC motif)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR003967(Potassium channel, voltage-dependent, ERG)|interpro:IPR005821(Ion transport)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018490|interpro:IPR035965|rcsb pdb:1BYW|rcsb pdb:1UJL|rcsb pdb:2L0W|rcsb pdb:2L1M|rcsb pdb:2L4R|rcsb pdb:2LE7|rcsb pdb:2N7G|rcsb pdb:4HP9|rcsb pdb:4HQA|rcsb pdb:5VA1|rcsb pdb:5VA2|rcsb pdb:5VA3|rcsb pdb:6SYG|ensembl:ENSG00000055118(gene)|ensembl:ENST00000262186(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003064"(regulation of heart rate by hormone)|reactome:R-HSA-1296072|reactome:R-HSA-5576890	refseq:NP_000229.1|refseq:NP_001191727.1|refseq:NP_742053.1|refseq:NP_742054.1|dip:DIP-48929N|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035690"|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:1902937"(inward rectifier potassium channel complex)|go:"GO:1903765"(negative regulation of potassium ion export across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000014(PAS)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR001610(PAC motif)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR003967(Potassium channel, voltage-dependent, ERG)|interpro:IPR005821(Ion transport)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018490|interpro:IPR035965|rcsb pdb:1BYW|rcsb pdb:1UJL|rcsb pdb:2L0W|rcsb pdb:2L1M|rcsb pdb:2L4R|rcsb pdb:2LE7|rcsb pdb:2N7G|rcsb pdb:4HP9|rcsb pdb:4HQA|rcsb pdb:5VA1|rcsb pdb:5VA2|rcsb pdb:5VA3|rcsb pdb:6SYG|ensembl:ENSG00000055118(gene)|ensembl:ENST00000262186(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003064"(regulation of heart rate by hormone)|reactome:R-HSA-1296072|reactome:R-HSA-5576890	-	-	-	figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/07/17	2014/10/16	rogid:GgrMfHJ+Gzu6yqgwiNxcMoDKbuY9606	rogid:GgrMfHJ+Gzu6yqgwiNxcMoDKbuY9606	intact-crc:FE5DD0435798101A|rigid:7nSv9PMyPToTOK/IXwPIAYOqDrE	false	sufficient binding region:1-135(IPR000014)	sufficient binding region:1-135(IPR000014)	4	0	psi-mi:"MI:0817"(molecular weight estimation by silver staining)	psi-mi:"MI:0817"(molecular weight estimation by silver staining)
uniprotkb:Q12809	uniprotkb:Q12809	intact:EBI-720643|uniprotkb:O75418|uniprotkb:O75680|uniprotkb:Q9BT72|uniprotkb:Q9BUT7|uniprotkb:Q9H3P0|uniprotkb:A5H1P7|uniprotkb:D3DX04|uniprotkb:C4PFH9|uniprotkb:Q708S9|ensembl:ENSP00000262186	intact:EBI-720643|uniprotkb:O75418|uniprotkb:O75680|uniprotkb:Q9BT72|uniprotkb:Q9BUT7|uniprotkb:Q9H3P0|uniprotkb:A5H1P7|uniprotkb:D3DX04|uniprotkb:C4PFH9|uniprotkb:Q708S9|ensembl:ENSP00000262186	psi-mi:kcnh2_human(display_long)|uniprotkb:Voltage-gated potassium channel subunit Kv11.1(gene name synonym)|uniprotkb:Ether-a-go-go-related gene potassium channel 1(gene name synonym)|uniprotkb:Eag homolog(gene name synonym)|uniprotkb:KCNH2(gene name)|psi-mi:KCNH2(display_short)|uniprotkb:ERG(gene name synonym)|uniprotkb:ERG1(gene name synonym)|uniprotkb:HERG(gene name synonym)	psi-mi:kcnh2_human(display_long)|uniprotkb:Voltage-gated potassium channel subunit Kv11.1(gene name synonym)|uniprotkb:Ether-a-go-go-related gene potassium channel 1(gene name synonym)|uniprotkb:Eag homolog(gene name synonym)|uniprotkb:KCNH2(gene name)|psi-mi:KCNH2(display_short)|uniprotkb:ERG(gene name synonym)|uniprotkb:ERG1(gene name synonym)|uniprotkb:HERG(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Li et al. (1997)	pubmed:8995352|imex:IM-22141	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-6920003|imex:IM-22141-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000229.1|refseq:NP_001191727.1|refseq:NP_742053.1|refseq:NP_742054.1|dip:DIP-48929N|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035690"|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:1902937"(inward rectifier potassium channel complex)|go:"GO:1903765"(negative regulation of potassium ion export across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000014(PAS)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR001610(PAC motif)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR003967(Potassium channel, voltage-dependent, ERG)|interpro:IPR005821(Ion transport)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018490|interpro:IPR035965|rcsb pdb:1BYW|rcsb pdb:1UJL|rcsb pdb:2L0W|rcsb pdb:2L1M|rcsb pdb:2L4R|rcsb pdb:2LE7|rcsb pdb:2N7G|rcsb pdb:4HP9|rcsb pdb:4HQA|rcsb pdb:5VA1|rcsb pdb:5VA2|rcsb pdb:5VA3|rcsb pdb:6SYG|ensembl:ENSG00000055118(gene)|ensembl:ENST00000262186(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003064"(regulation of heart rate by hormone)|reactome:R-HSA-1296072|reactome:R-HSA-5576890	refseq:NP_000229.1|refseq:NP_001191727.1|refseq:NP_742053.1|refseq:NP_742054.1|dip:DIP-48929N|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035690"|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:1902937"(inward rectifier potassium channel complex)|go:"GO:1903765"(negative regulation of potassium ion export across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000014(PAS)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR001610(PAC motif)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR003967(Potassium channel, voltage-dependent, ERG)|interpro:IPR005821(Ion transport)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018490|interpro:IPR035965|rcsb pdb:1BYW|rcsb pdb:1UJL|rcsb pdb:2L0W|rcsb pdb:2L1M|rcsb pdb:2L4R|rcsb pdb:2LE7|rcsb pdb:2N7G|rcsb pdb:4HP9|rcsb pdb:4HQA|rcsb pdb:5VA1|rcsb pdb:5VA2|rcsb pdb:5VA3|rcsb pdb:6SYG|ensembl:ENSG00000055118(gene)|ensembl:ENST00000262186(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003064"(regulation of heart rate by hormone)|reactome:R-HSA-1296072|reactome:R-HSA-5576890	-	-	-	figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/07/17	2014/10/16	rogid:GgrMfHJ+Gzu6yqgwiNxcMoDKbuY9606	rogid:GgrMfHJ+Gzu6yqgwiNxcMoDKbuY9606	intact-crc:B62420C719320F5B|rigid:7nSv9PMyPToTOK/IXwPIAYOqDrE	false	sufficient binding region:1-135(IPR000014)	sufficient binding region:1-135(IPR000014)	2	0	psi-mi:"MI:0817"(molecular weight estimation by silver staining)	psi-mi:"MI:0817"(molecular weight estimation by silver staining)
uniprotkb:Q12809	uniprotkb:Q12809	intact:EBI-720643|uniprotkb:O75418|uniprotkb:O75680|uniprotkb:Q9BT72|uniprotkb:Q9BUT7|uniprotkb:Q9H3P0|uniprotkb:A5H1P7|uniprotkb:D3DX04|uniprotkb:C4PFH9|uniprotkb:Q708S9|ensembl:ENSP00000262186	intact:EBI-720643|uniprotkb:O75418|uniprotkb:O75680|uniprotkb:Q9BT72|uniprotkb:Q9BUT7|uniprotkb:Q9H3P0|uniprotkb:A5H1P7|uniprotkb:D3DX04|uniprotkb:C4PFH9|uniprotkb:Q708S9|ensembl:ENSP00000262186	psi-mi:kcnh2_human(display_long)|uniprotkb:Voltage-gated potassium channel subunit Kv11.1(gene name synonym)|uniprotkb:Ether-a-go-go-related gene potassium channel 1(gene name synonym)|uniprotkb:Eag homolog(gene name synonym)|uniprotkb:KCNH2(gene name)|psi-mi:KCNH2(display_short)|uniprotkb:ERG(gene name synonym)|uniprotkb:ERG1(gene name synonym)|uniprotkb:HERG(gene name synonym)	psi-mi:kcnh2_human(display_long)|uniprotkb:Voltage-gated potassium channel subunit Kv11.1(gene name synonym)|uniprotkb:Ether-a-go-go-related gene potassium channel 1(gene name synonym)|uniprotkb:Eag homolog(gene name synonym)|uniprotkb:KCNH2(gene name)|psi-mi:KCNH2(display_short)|uniprotkb:ERG(gene name synonym)|uniprotkb:ERG1(gene name synonym)|uniprotkb:HERG(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Li et al. (1997)	pubmed:8995352|imex:IM-22141	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-6919927|imex:IM-22141-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000229.1|refseq:NP_001191727.1|refseq:NP_742053.1|refseq:NP_742054.1|dip:DIP-48929N|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035690"|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:1902937"(inward rectifier potassium channel complex)|go:"GO:1903765"(negative regulation of potassium ion export across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000014(PAS)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR001610(PAC motif)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR003967(Potassium channel, voltage-dependent, ERG)|interpro:IPR005821(Ion transport)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018490|interpro:IPR035965|rcsb pdb:1BYW|rcsb pdb:1UJL|rcsb pdb:2L0W|rcsb pdb:2L1M|rcsb pdb:2L4R|rcsb pdb:2LE7|rcsb pdb:2N7G|rcsb pdb:4HP9|rcsb pdb:4HQA|rcsb pdb:5VA1|rcsb pdb:5VA2|rcsb pdb:5VA3|rcsb pdb:6SYG|ensembl:ENSG00000055118(gene)|ensembl:ENST00000262186(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003064"(regulation of heart rate by hormone)|reactome:R-HSA-1296072|reactome:R-HSA-5576890	refseq:NP_000229.1|refseq:NP_001191727.1|refseq:NP_742053.1|refseq:NP_742054.1|dip:DIP-48929N|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035690"|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:1902937"(inward rectifier potassium channel complex)|go:"GO:1903765"(negative regulation of potassium ion export across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000014(PAS)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR001610(PAC motif)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR003967(Potassium channel, voltage-dependent, ERG)|interpro:IPR005821(Ion transport)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018490|interpro:IPR035965|rcsb pdb:1BYW|rcsb pdb:1UJL|rcsb pdb:2L0W|rcsb pdb:2L1M|rcsb pdb:2L4R|rcsb pdb:2LE7|rcsb pdb:2N7G|rcsb pdb:4HP9|rcsb pdb:4HQA|rcsb pdb:5VA1|rcsb pdb:5VA2|rcsb pdb:5VA3|rcsb pdb:6SYG|ensembl:ENSG00000055118(gene)|ensembl:ENST00000262186(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003064"(regulation of heart rate by hormone)|reactome:R-HSA-1296072|reactome:R-HSA-5576890	-	-	-	figure legend:1B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2013/07/17	2014/10/16	rogid:GgrMfHJ+Gzu6yqgwiNxcMoDKbuY9606	rogid:GgrMfHJ+Gzu6yqgwiNxcMoDKbuY9606	intact-crc:0D94FF0123A617AB|rigid:imi9NmfAysxxCdFFeAVpMKfTKJ4	false	glutathione s tranferase tag:?-?|sufficient binding region:1-135(IPR000014)	sufficient binding region:1-135(IPR000014)|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0817"(molecular weight estimation by silver staining)	psi-mi:"MI:0817"(molecular weight estimation by silver staining)