#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B intact:EBI-6508950 uniprotkb:P07013 chebi:"CHEBI:9160" intact:EBI-1125223|uniprotkb:Q2M6A4|ensemblbacteria:AAC77158|ensemblbacteria:BAE78202 psi-mi:ssdna-1(display_short)|psi-mi:EBI-6508950(display_long) psi-mi:prib_ecoli(display_long)|uniprotkb:priB(gene name)|psi-mi:priB(display_short)|uniprotkb:b4201(locus name)|uniprotkb:JW4159(locus name) psi-mi:"MI:0071"(molecular sieving) Ng et al. (1996) imex:IM-18709|pubmed:8663105 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-6557679|imex:IM-18709-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0680"(single stranded deoxyribonucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_418622.1|refseq:WP_001315977.1|ensemblbacteria:b4201(gene)|ensemblbacteria:BAE78202(gene)|ensemblbacteria:BAE78202(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006276"(plasmid maintenance)|go:"GO:0009314"(response to radiation)|go:"GO:0042802"(identical protein binding)|go:"GO:1990099"(pre-primosome complex)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR023646|rcsb pdb:1TXY|rcsb pdb:1V1Q|rcsb pdb:1WOC|rcsb pdb:2CCZ|rcsb pdb:2PNH|rcsb pdb:5WQV|ensemblbacteria:AAC77158(transcript)|dip:DIP-10563N go:"GO:0006270"(DNA replication initiation) - - figure legend:Fig. 1b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/11 2020/01/31 - rogid:t9m94Sm9Zz1cXCqAybm67nkDNRQ83333 intact-crc:F443E96B23E2AEAB false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P0ACB0 uniprotkb:P0AEF0 intact:EBI-548978|uniprotkb:P03005|uniprotkb:Q2M6Q2|ensemblbacteria:AAC77022|ensemblbacteria:BAE78054 intact:EBI-549012|uniprotkb:P07905|uniprotkb:Q2M5V5|ensemblbacteria:AAC77317|ensemblbacteria:BAE78351 psi-mi:dnab_ecoli(display_long)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpA(gene name synonym)|uniprotkb:b4052(locus name)|uniprotkb:JW4012(locus name) psi-mi:dnac_ecoli(display_long)|uniprotkb:dnaC(gene name)|psi-mi:dnaC(display_short)|uniprotkb:dnaD(gene name synonym)|uniprotkb:b4361(locus name)|uniprotkb:JW4325(locus name) psi-mi:"MI:0071"(molecular sieving) Ng et al. (1996) imex:IM-18709|pubmed:8663105 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6557664|imex:IM-18709-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_418476.1|refseq:WP_000918363.1|dip:DIP-9456N|ensemblbacteria:AAC77022(transcript)|ensemblbacteria:b4052(gene)|ensemblbacteria:BAE78054(gene)|ensemblbacteria:BAE78054(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|interpro:IPR027417|interpro:IPR036185|rcsb pdb:1B79|rcsb pdb:1JWE|rcsb pdb:6BBM|rcsb pdb:6KZA|rcsb pdb:6QEL|rcsb pdb:6QEM refseq:NP_418781.1|refseq:WP_000799911.1|dip:DIP-9457N|ensemblbacteria:AAC77317(transcript)|ensemblbacteria:b4361(gene)|ensemblbacteria:BAE78351(gene)|ensemblbacteria:BAE78351(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:1990077"(primosome complex)|interpro:IPR002611(IstB-like ATP-binding protein)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|interpro:IPR028350|rcsb pdb:6KZA|rcsb pdb:6QEL|rcsb pdb:6QEM go:"GO:0006270"(DNA replication initiation) - - figure legend:Fig. 1a, b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/11 2014/10/16 rogid:czmOnQQpFov7eFmCjLGjNhkbJ7M83333 rogid:JuiZiIQR0NdZ0Dm8/F/baTwL89A83333 intact-crc:872590BA29ABD4DA|rigid:OKTWNERiE7rz5aq+QsJzSxXp4oY false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P0ACB0 uniprotkb:P0A8J2 intact:EBI-548978|uniprotkb:P03005|uniprotkb:Q2M6Q2|ensemblbacteria:AAC77022|ensemblbacteria:BAE78054 intact:EBI-549621|uniprotkb:P07904|uniprotkb:Q2M5V4|ensemblbacteria:AAC77318|ensemblbacteria:BAE78352 psi-mi:dnab_ecoli(display_long)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpA(gene name synonym)|uniprotkb:b4052(locus name)|uniprotkb:JW4012(locus name) psi-mi:dnat_ecoli(display_long)|uniprotkb:dnaT(gene name)|psi-mi:dnaT(display_short)|uniprotkb:b4362(locus name)|uniprotkb:JW4326(locus name)|uniprotkb:Primosomal protein I(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Ng et al. (1996) imex:IM-18709|pubmed:8663105 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6557664|imex:IM-18709-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_418476.1|refseq:WP_000918363.1|dip:DIP-9456N|ensemblbacteria:AAC77022(transcript)|ensemblbacteria:b4052(gene)|ensemblbacteria:BAE78054(gene)|ensemblbacteria:BAE78054(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|interpro:IPR027417|interpro:IPR036185|rcsb pdb:1B79|rcsb pdb:1JWE|rcsb pdb:6BBM|rcsb pdb:6KZA|rcsb pdb:6QEL|rcsb pdb:6QEM refseq:NP_418782.1|refseq:WP_000098818.1|dip:DIP-47957N|ensemblbacteria:AAC77318(transcript)|ensemblbacteria:b4362(gene)|ensemblbacteria:BAE78352(gene)|ensemblbacteria:BAE78352(transcript)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0042802"(identical protein binding)|go:"GO:1990077"(primosome complex)|interpro:IPR020917|interpro:IPR040480|rcsb pdb:2RU8|rcsb pdb:4OU6|rcsb pdb:4OU7 go:"GO:0006270"(DNA replication initiation) - crc64:8DE048A3B2A6235B figure legend:Fig. 1a, b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/11 2014/10/16 rogid:czmOnQQpFov7eFmCjLGjNhkbJ7M83333 rogid:Ca5J+AWjsjBGNNpTU2itH6zmSZc83333 intact-crc:872590BA29ABD4DA|rigid:OKTWNERiE7rz5aq+QsJzSxXp4oY false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P0ACB0 uniprotkb:P23862 intact:EBI-548978|uniprotkb:P03005|uniprotkb:Q2M6Q2|ensemblbacteria:AAC77022|ensemblbacteria:BAE78054 intact:EBI-1117383|uniprotkb:Q2MBW0|ensemblbacteria:AAC73569|ensemblbacteria:BAE76246 psi-mi:dnab_ecoli(display_long)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpA(gene name synonym)|uniprotkb:b4052(locus name)|uniprotkb:JW4012(locus name) psi-mi:pric_ecoli(display_long)|uniprotkb:priC(gene name)|psi-mi:priC(display_short)|uniprotkb:b0467(locus name)|uniprotkb:JW0456(locus name) psi-mi:"MI:0071"(molecular sieving) Ng et al. (1996) imex:IM-18709|pubmed:8663105 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6557664|imex:IM-18709-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_418476.1|refseq:WP_000918363.1|dip:DIP-9456N|ensemblbacteria:AAC77022(transcript)|ensemblbacteria:b4052(gene)|ensemblbacteria:BAE78054(gene)|ensemblbacteria:BAE78054(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|interpro:IPR027417|interpro:IPR036185|rcsb pdb:1B79|rcsb pdb:1JWE|rcsb pdb:6BBM|rcsb pdb:6KZA|rcsb pdb:6QEL|rcsb pdb:6QEM ensemblbacteria:AAC73569(transcript)|ensemblbacteria:b0467(gene)|ensemblbacteria:BAE76246(gene)|ensemblbacteria:BAE76246(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:1990077"(primosome complex)|interpro:IPR010890(Primosomal replication priB and priC)|interpro:IPR038338|rcsb pdb:2RT6|refseq:WP_000844874.1|refseq:NP_415000.1|dip:DIP-10564N go:"GO:0006270"(DNA replication initiation) - - figure legend:Fig. 1a, b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/11 2014/10/16 rogid:czmOnQQpFov7eFmCjLGjNhkbJ7M83333 rogid:7vsr929ivZk++tx1fxgUnL1NNaA83333 intact-crc:872590BA29ABD4DA|rigid:OKTWNERiE7rz5aq+QsJzSxXp4oY false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P0ACB0 uniprotkb:P0A8J2 intact:EBI-548978|uniprotkb:P03005|uniprotkb:Q2M6Q2|ensemblbacteria:AAC77022|ensemblbacteria:BAE78054 intact:EBI-549621|uniprotkb:P07904|uniprotkb:Q2M5V4|ensemblbacteria:AAC77318|ensemblbacteria:BAE78352 psi-mi:dnab_ecoli(display_long)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpA(gene name synonym)|uniprotkb:b4052(locus name)|uniprotkb:JW4012(locus name) psi-mi:dnat_ecoli(display_long)|uniprotkb:dnaT(gene name)|psi-mi:dnaT(display_short)|uniprotkb:b4362(locus name)|uniprotkb:JW4326(locus name)|uniprotkb:Primosomal protein I(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Ng et al. (1996) imex:IM-18709|pubmed:8663105 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6557653|imex:IM-18709-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_418476.1|refseq:WP_000918363.1|dip:DIP-9456N|ensemblbacteria:AAC77022(transcript)|ensemblbacteria:b4052(gene)|ensemblbacteria:BAE78054(gene)|ensemblbacteria:BAE78054(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|interpro:IPR027417|interpro:IPR036185|rcsb pdb:1B79|rcsb pdb:1JWE|rcsb pdb:6BBM|rcsb pdb:6KZA|rcsb pdb:6QEL|rcsb pdb:6QEM refseq:NP_418782.1|refseq:WP_000098818.1|dip:DIP-47957N|ensemblbacteria:AAC77318(transcript)|ensemblbacteria:b4362(gene)|ensemblbacteria:BAE78352(gene)|ensemblbacteria:BAE78352(transcript)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0042802"(identical protein binding)|go:"GO:1990077"(primosome complex)|interpro:IPR020917|interpro:IPR040480|rcsb pdb:2RU8|rcsb pdb:4OU6|rcsb pdb:4OU7 go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0006270"(DNA replication initiation) - crc64:8DE048A3B2A6235B figure legend:Fig. 1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/11 2020/01/31 rogid:czmOnQQpFov7eFmCjLGjNhkbJ7M83333 rogid:Ca5J+AWjsjBGNNpTU2itH6zmSZc83333 intact-crc:4F4AF00F052FF602 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P0ACB0 uniprotkb:P17888 intact:EBI-548978|uniprotkb:P03005|uniprotkb:Q2M6Q2|ensemblbacteria:AAC77022|ensemblbacteria:BAE78054 intact:EBI-552050|uniprotkb:Q2M8N1|ensemblbacteria:AAC76917|ensemblbacteria:BAE77375 psi-mi:dnab_ecoli(display_long)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpA(gene name synonym)|uniprotkb:b4052(locus name)|uniprotkb:JW4012(locus name) psi-mi:pria_ecoli(display_long)|uniprotkb:priA(gene name)|psi-mi:priA(display_short)|uniprotkb:b3935(locus name)|uniprotkb:Replication factor Y(gene name synonym)|uniprotkb:JW3906(locus name)|uniprotkb:ATP-dependent helicase PriA(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Ng et al. (1996) imex:IM-18709|pubmed:8663105 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6557653|imex:IM-18709-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_418476.1|refseq:WP_000918363.1|dip:DIP-9456N|ensemblbacteria:AAC77022(transcript)|ensemblbacteria:b4052(gene)|ensemblbacteria:BAE78054(gene)|ensemblbacteria:BAE78054(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|interpro:IPR027417|interpro:IPR036185|rcsb pdb:1B79|rcsb pdb:1JWE|rcsb pdb:6BBM|rcsb pdb:6KZA|rcsb pdb:6QEL|rcsb pdb:6QEM refseq:NP_418370.1|refseq:WP_001301269.1|dip:DIP-10562N|ensemblbacteria:AAC76917(transcript)|ensemblbacteria:b3935(gene)|ensemblbacteria:BAE77375(gene)|ensemblbacteria:BAE77375(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006276"(plasmid maintenance)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990077"(primosome complex)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR005259(Primosomal protein n)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR040498|interpro:IPR041222|interpro:IPR041236|interpro:IPR042115|rcsb pdb:2D7E|rcsb pdb:2D7G|rcsb pdb:2D7H|rcsb pdb:2DWL|rcsb pdb:2DWM|rcsb pdb:2DWN|rcsb pdb:6DCR go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0006270"(DNA replication initiation) - - figure legend:Fig. 1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/11 2020/01/31 rogid:czmOnQQpFov7eFmCjLGjNhkbJ7M83333 rogid:QD9LmjaQ1XsaW1D5sdGnrHTihgQ83333 intact-crc:4F4AF00F052FF602 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P0ACB0 uniprotkb:P07013 intact:EBI-548978|uniprotkb:P03005|uniprotkb:Q2M6Q2|ensemblbacteria:AAC77022|ensemblbacteria:BAE78054 intact:EBI-1125223|uniprotkb:Q2M6A4|ensemblbacteria:AAC77158|ensemblbacteria:BAE78202 psi-mi:dnab_ecoli(display_long)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpA(gene name synonym)|uniprotkb:b4052(locus name)|uniprotkb:JW4012(locus name) psi-mi:prib_ecoli(display_long)|uniprotkb:priB(gene name)|psi-mi:priB(display_short)|uniprotkb:b4201(locus name)|uniprotkb:JW4159(locus name) psi-mi:"MI:0071"(molecular sieving) Ng et al. (1996) imex:IM-18709|pubmed:8663105 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6557653|imex:IM-18709-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_418476.1|refseq:WP_000918363.1|dip:DIP-9456N|ensemblbacteria:AAC77022(transcript)|ensemblbacteria:b4052(gene)|ensemblbacteria:BAE78054(gene)|ensemblbacteria:BAE78054(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|interpro:IPR027417|interpro:IPR036185|rcsb pdb:1B79|rcsb pdb:1JWE|rcsb pdb:6BBM|rcsb pdb:6KZA|rcsb pdb:6QEL|rcsb pdb:6QEM refseq:NP_418622.1|refseq:WP_001315977.1|ensemblbacteria:b4201(gene)|ensemblbacteria:BAE78202(gene)|ensemblbacteria:BAE78202(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006276"(plasmid maintenance)|go:"GO:0009314"(response to radiation)|go:"GO:0042802"(identical protein binding)|go:"GO:1990099"(pre-primosome complex)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR023646|rcsb pdb:1TXY|rcsb pdb:1V1Q|rcsb pdb:1WOC|rcsb pdb:2CCZ|rcsb pdb:2PNH|rcsb pdb:5WQV|ensemblbacteria:AAC77158(transcript)|dip:DIP-10563N go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0006270"(DNA replication initiation) - - figure legend:Fig. 1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/11 2020/01/31 rogid:czmOnQQpFov7eFmCjLGjNhkbJ7M83333 rogid:t9m94Sm9Zz1cXCqAybm67nkDNRQ83333 intact-crc:4F4AF00F052FF602 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P0ACB0 uniprotkb:P23862 intact:EBI-548978|uniprotkb:P03005|uniprotkb:Q2M6Q2|ensemblbacteria:AAC77022|ensemblbacteria:BAE78054 intact:EBI-1117383|uniprotkb:Q2MBW0|ensemblbacteria:AAC73569|ensemblbacteria:BAE76246 psi-mi:dnab_ecoli(display_long)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpA(gene name synonym)|uniprotkb:b4052(locus name)|uniprotkb:JW4012(locus name) psi-mi:pric_ecoli(display_long)|uniprotkb:priC(gene name)|psi-mi:priC(display_short)|uniprotkb:b0467(locus name)|uniprotkb:JW0456(locus name) psi-mi:"MI:0071"(molecular sieving) Ng et al. (1996) imex:IM-18709|pubmed:8663105 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6557653|imex:IM-18709-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_418476.1|refseq:WP_000918363.1|dip:DIP-9456N|ensemblbacteria:AAC77022(transcript)|ensemblbacteria:b4052(gene)|ensemblbacteria:BAE78054(gene)|ensemblbacteria:BAE78054(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|interpro:IPR027417|interpro:IPR036185|rcsb pdb:1B79|rcsb pdb:1JWE|rcsb pdb:6BBM|rcsb pdb:6KZA|rcsb pdb:6QEL|rcsb pdb:6QEM ensemblbacteria:AAC73569(transcript)|ensemblbacteria:b0467(gene)|ensemblbacteria:BAE76246(gene)|ensemblbacteria:BAE76246(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:1990077"(primosome complex)|interpro:IPR010890(Primosomal replication priB and priC)|interpro:IPR038338|rcsb pdb:2RT6|refseq:WP_000844874.1|refseq:NP_415000.1|dip:DIP-10564N go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0006270"(DNA replication initiation) - - figure legend:Fig. 1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/11 2020/01/31 rogid:czmOnQQpFov7eFmCjLGjNhkbJ7M83333 rogid:7vsr929ivZk++tx1fxgUnL1NNaA83333 intact-crc:4F4AF00F052FF602 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P0ACB0 intact:EBI-6508950 intact:EBI-548978|uniprotkb:P03005|uniprotkb:Q2M6Q2|ensemblbacteria:AAC77022|ensemblbacteria:BAE78054 chebi:"CHEBI:9160" psi-mi:dnab_ecoli(display_long)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpA(gene name synonym)|uniprotkb:b4052(locus name)|uniprotkb:JW4012(locus name) psi-mi:ssdna-1(display_short)|psi-mi:EBI-6508950(display_long) psi-mi:"MI:0071"(molecular sieving) Ng et al. (1996) imex:IM-18709|pubmed:8663105 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6557653|imex:IM-18709-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0680"(single stranded deoxyribonucleic acid) refseq:NP_418476.1|refseq:WP_000918363.1|dip:DIP-9456N|ensemblbacteria:AAC77022(transcript)|ensemblbacteria:b4052(gene)|ensemblbacteria:BAE78054(gene)|ensemblbacteria:BAE78054(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|interpro:IPR027417|interpro:IPR036185|rcsb pdb:1B79|rcsb pdb:1JWE|rcsb pdb:6BBM|rcsb pdb:6KZA|rcsb pdb:6QEL|rcsb pdb:6QEM - go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0006270"(DNA replication initiation) - - figure legend:Fig. 1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/11 2020/01/31 rogid:czmOnQQpFov7eFmCjLGjNhkbJ7M83333 - intact-crc:4F4AF00F052FF602 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P0ACB0 uniprotkb:P0AEF0 intact:EBI-548978|uniprotkb:P03005|uniprotkb:Q2M6Q2|ensemblbacteria:AAC77022|ensemblbacteria:BAE78054 intact:EBI-549012|uniprotkb:P07905|uniprotkb:Q2M5V5|ensemblbacteria:AAC77317|ensemblbacteria:BAE78351 psi-mi:dnab_ecoli(display_long)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpA(gene name synonym)|uniprotkb:b4052(locus name)|uniprotkb:JW4012(locus name) psi-mi:dnac_ecoli(display_long)|uniprotkb:dnaC(gene name)|psi-mi:dnaC(display_short)|uniprotkb:dnaD(gene name synonym)|uniprotkb:b4361(locus name)|uniprotkb:JW4325(locus name) psi-mi:"MI:0071"(molecular sieving) Ng et al. (1996) imex:IM-18709|pubmed:8663105 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6556807|imex:IM-18709-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_418476.1|refseq:WP_000918363.1|dip:DIP-9456N|ensemblbacteria:AAC77022(transcript)|ensemblbacteria:b4052(gene)|ensemblbacteria:BAE78054(gene)|ensemblbacteria:BAE78054(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|interpro:IPR027417|interpro:IPR036185|rcsb pdb:1B79|rcsb pdb:1JWE|rcsb pdb:6BBM|rcsb pdb:6KZA|rcsb pdb:6QEL|rcsb pdb:6QEM refseq:NP_418781.1|refseq:WP_000799911.1|dip:DIP-9457N|ensemblbacteria:AAC77317(transcript)|ensemblbacteria:b4361(gene)|ensemblbacteria:BAE78351(gene)|ensemblbacteria:BAE78351(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:1990077"(primosome complex)|interpro:IPR002611(IstB-like ATP-binding protein)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|interpro:IPR028350|rcsb pdb:6KZA|rcsb pdb:6QEL|rcsb pdb:6QEM go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0006270"(DNA replication initiation) - - figure legend:Fig. 1a, 2, 3|comment:DnaC and PriC form very weak interactions with the other preprimosome proteins.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/11 2014/10/16 rogid:czmOnQQpFov7eFmCjLGjNhkbJ7M83333 rogid:JuiZiIQR0NdZ0Dm8/F/baTwL89A83333 intact-crc:577165E525E0A575|rigid:ScU/c43YcrTQGELqtQqRgnagiSU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P0ACB0 uniprotkb:P0A8J2 intact:EBI-548978|uniprotkb:P03005|uniprotkb:Q2M6Q2|ensemblbacteria:AAC77022|ensemblbacteria:BAE78054 intact:EBI-549621|uniprotkb:P07904|uniprotkb:Q2M5V4|ensemblbacteria:AAC77318|ensemblbacteria:BAE78352 psi-mi:dnab_ecoli(display_long)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpA(gene name synonym)|uniprotkb:b4052(locus name)|uniprotkb:JW4012(locus name) psi-mi:dnat_ecoli(display_long)|uniprotkb:dnaT(gene name)|psi-mi:dnaT(display_short)|uniprotkb:b4362(locus name)|uniprotkb:JW4326(locus name)|uniprotkb:Primosomal protein I(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Ng et al. (1996) imex:IM-18709|pubmed:8663105 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6556807|imex:IM-18709-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_418476.1|refseq:WP_000918363.1|dip:DIP-9456N|ensemblbacteria:AAC77022(transcript)|ensemblbacteria:b4052(gene)|ensemblbacteria:BAE78054(gene)|ensemblbacteria:BAE78054(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|interpro:IPR027417|interpro:IPR036185|rcsb pdb:1B79|rcsb pdb:1JWE|rcsb pdb:6BBM|rcsb pdb:6KZA|rcsb pdb:6QEL|rcsb pdb:6QEM refseq:NP_418782.1|refseq:WP_000098818.1|dip:DIP-47957N|ensemblbacteria:AAC77318(transcript)|ensemblbacteria:b4362(gene)|ensemblbacteria:BAE78352(gene)|ensemblbacteria:BAE78352(transcript)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0042802"(identical protein binding)|go:"GO:1990077"(primosome complex)|interpro:IPR020917|interpro:IPR040480|rcsb pdb:2RU8|rcsb pdb:4OU6|rcsb pdb:4OU7 go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0006270"(DNA replication initiation) - crc64:8DE048A3B2A6235B figure legend:Fig. 1a, 2, 3|comment:DnaC and PriC form very weak interactions with the other preprimosome proteins.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/11 2014/10/16 rogid:czmOnQQpFov7eFmCjLGjNhkbJ7M83333 rogid:Ca5J+AWjsjBGNNpTU2itH6zmSZc83333 intact-crc:577165E525E0A575|rigid:ScU/c43YcrTQGELqtQqRgnagiSU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P0ACB0 uniprotkb:P17888 intact:EBI-548978|uniprotkb:P03005|uniprotkb:Q2M6Q2|ensemblbacteria:AAC77022|ensemblbacteria:BAE78054 intact:EBI-552050|uniprotkb:Q2M8N1|ensemblbacteria:AAC76917|ensemblbacteria:BAE77375 psi-mi:dnab_ecoli(display_long)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpA(gene name synonym)|uniprotkb:b4052(locus name)|uniprotkb:JW4012(locus name) psi-mi:pria_ecoli(display_long)|uniprotkb:priA(gene name)|psi-mi:priA(display_short)|uniprotkb:b3935(locus name)|uniprotkb:Replication factor Y(gene name synonym)|uniprotkb:JW3906(locus name)|uniprotkb:ATP-dependent helicase PriA(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Ng et al. (1996) imex:IM-18709|pubmed:8663105 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6556807|imex:IM-18709-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_418476.1|refseq:WP_000918363.1|dip:DIP-9456N|ensemblbacteria:AAC77022(transcript)|ensemblbacteria:b4052(gene)|ensemblbacteria:BAE78054(gene)|ensemblbacteria:BAE78054(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|interpro:IPR027417|interpro:IPR036185|rcsb pdb:1B79|rcsb pdb:1JWE|rcsb pdb:6BBM|rcsb pdb:6KZA|rcsb pdb:6QEL|rcsb pdb:6QEM refseq:NP_418370.1|refseq:WP_001301269.1|dip:DIP-10562N|ensemblbacteria:AAC76917(transcript)|ensemblbacteria:b3935(gene)|ensemblbacteria:BAE77375(gene)|ensemblbacteria:BAE77375(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006276"(plasmid maintenance)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990077"(primosome complex)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR005259(Primosomal protein n)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR040498|interpro:IPR041222|interpro:IPR041236|interpro:IPR042115|rcsb pdb:2D7E|rcsb pdb:2D7G|rcsb pdb:2D7H|rcsb pdb:2DWL|rcsb pdb:2DWM|rcsb pdb:2DWN|rcsb pdb:6DCR go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0006270"(DNA replication initiation) - - figure legend:Fig. 1a, 2, 3|comment:DnaC and PriC form very weak interactions with the other preprimosome proteins.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/11 2014/10/16 rogid:czmOnQQpFov7eFmCjLGjNhkbJ7M83333 rogid:QD9LmjaQ1XsaW1D5sdGnrHTihgQ83333 intact-crc:577165E525E0A575|rigid:ScU/c43YcrTQGELqtQqRgnagiSU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P0ACB0 uniprotkb:P07013 intact:EBI-548978|uniprotkb:P03005|uniprotkb:Q2M6Q2|ensemblbacteria:AAC77022|ensemblbacteria:BAE78054 intact:EBI-1125223|uniprotkb:Q2M6A4|ensemblbacteria:AAC77158|ensemblbacteria:BAE78202 psi-mi:dnab_ecoli(display_long)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpA(gene name synonym)|uniprotkb:b4052(locus name)|uniprotkb:JW4012(locus name) psi-mi:prib_ecoli(display_long)|uniprotkb:priB(gene name)|psi-mi:priB(display_short)|uniprotkb:b4201(locus name)|uniprotkb:JW4159(locus name) psi-mi:"MI:0071"(molecular sieving) Ng et al. (1996) imex:IM-18709|pubmed:8663105 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6556807|imex:IM-18709-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_418476.1|refseq:WP_000918363.1|dip:DIP-9456N|ensemblbacteria:AAC77022(transcript)|ensemblbacteria:b4052(gene)|ensemblbacteria:BAE78054(gene)|ensemblbacteria:BAE78054(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|interpro:IPR027417|interpro:IPR036185|rcsb pdb:1B79|rcsb pdb:1JWE|rcsb pdb:6BBM|rcsb pdb:6KZA|rcsb pdb:6QEL|rcsb pdb:6QEM refseq:NP_418622.1|refseq:WP_001315977.1|ensemblbacteria:b4201(gene)|ensemblbacteria:BAE78202(gene)|ensemblbacteria:BAE78202(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006276"(plasmid maintenance)|go:"GO:0009314"(response to radiation)|go:"GO:0042802"(identical protein binding)|go:"GO:1990099"(pre-primosome complex)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR023646|rcsb pdb:1TXY|rcsb pdb:1V1Q|rcsb pdb:1WOC|rcsb pdb:2CCZ|rcsb pdb:2PNH|rcsb pdb:5WQV|ensemblbacteria:AAC77158(transcript)|dip:DIP-10563N go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0006270"(DNA replication initiation) - - figure legend:Fig. 1a, 2, 3|comment:DnaC and PriC form very weak interactions with the other preprimosome proteins.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/11 2014/10/16 rogid:czmOnQQpFov7eFmCjLGjNhkbJ7M83333 rogid:t9m94Sm9Zz1cXCqAybm67nkDNRQ83333 intact-crc:577165E525E0A575|rigid:ScU/c43YcrTQGELqtQqRgnagiSU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P0ACB0 uniprotkb:P23862 intact:EBI-548978|uniprotkb:P03005|uniprotkb:Q2M6Q2|ensemblbacteria:AAC77022|ensemblbacteria:BAE78054 intact:EBI-1117383|uniprotkb:Q2MBW0|ensemblbacteria:AAC73569|ensemblbacteria:BAE76246 psi-mi:dnab_ecoli(display_long)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpA(gene name synonym)|uniprotkb:b4052(locus name)|uniprotkb:JW4012(locus name) psi-mi:pric_ecoli(display_long)|uniprotkb:priC(gene name)|psi-mi:priC(display_short)|uniprotkb:b0467(locus name)|uniprotkb:JW0456(locus name) psi-mi:"MI:0071"(molecular sieving) Ng et al. (1996) imex:IM-18709|pubmed:8663105 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6556807|imex:IM-18709-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_418476.1|refseq:WP_000918363.1|dip:DIP-9456N|ensemblbacteria:AAC77022(transcript)|ensemblbacteria:b4052(gene)|ensemblbacteria:BAE78054(gene)|ensemblbacteria:BAE78054(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|interpro:IPR027417|interpro:IPR036185|rcsb pdb:1B79|rcsb pdb:1JWE|rcsb pdb:6BBM|rcsb pdb:6KZA|rcsb pdb:6QEL|rcsb pdb:6QEM ensemblbacteria:AAC73569(transcript)|ensemblbacteria:b0467(gene)|ensemblbacteria:BAE76246(gene)|ensemblbacteria:BAE76246(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:1990077"(primosome complex)|interpro:IPR010890(Primosomal replication priB and priC)|interpro:IPR038338|rcsb pdb:2RT6|refseq:WP_000844874.1|refseq:NP_415000.1|dip:DIP-10564N go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0006270"(DNA replication initiation) - - figure legend:Fig. 1a, 2, 3|comment:DnaC and PriC form very weak interactions with the other preprimosome proteins.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/11 2014/10/16 rogid:czmOnQQpFov7eFmCjLGjNhkbJ7M83333 rogid:7vsr929ivZk++tx1fxgUnL1NNaA83333 intact-crc:577165E525E0A575|rigid:ScU/c43YcrTQGELqtQqRgnagiSU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P0ACB0 uniprotkb:P0AEF0 intact:EBI-548978|uniprotkb:P03005|uniprotkb:Q2M6Q2|ensemblbacteria:AAC77022|ensemblbacteria:BAE78054 intact:EBI-549012|uniprotkb:P07905|uniprotkb:Q2M5V5|ensemblbacteria:AAC77317|ensemblbacteria:BAE78351 psi-mi:dnab_ecoli(display_long)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpA(gene name synonym)|uniprotkb:b4052(locus name)|uniprotkb:JW4012(locus name) psi-mi:dnac_ecoli(display_long)|uniprotkb:dnaC(gene name)|psi-mi:dnaC(display_short)|uniprotkb:dnaD(gene name synonym)|uniprotkb:b4361(locus name)|uniprotkb:JW4325(locus name) psi-mi:"MI:0071"(molecular sieving) Ng et al. (1996) imex:IM-18709|pubmed:8663105 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6556816|imex:IM-18709-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_418476.1|refseq:WP_000918363.1|dip:DIP-9456N|ensemblbacteria:AAC77022(transcript)|ensemblbacteria:b4052(gene)|ensemblbacteria:BAE78054(gene)|ensemblbacteria:BAE78054(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|interpro:IPR027417|interpro:IPR036185|rcsb pdb:1B79|rcsb pdb:1JWE|rcsb pdb:6BBM|rcsb pdb:6KZA|rcsb pdb:6QEL|rcsb pdb:6QEM refseq:NP_418781.1|refseq:WP_000799911.1|dip:DIP-9457N|ensemblbacteria:AAC77317(transcript)|ensemblbacteria:b4361(gene)|ensemblbacteria:BAE78351(gene)|ensemblbacteria:BAE78351(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:1990077"(primosome complex)|interpro:IPR002611(IstB-like ATP-binding protein)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|interpro:IPR028350|rcsb pdb:6KZA|rcsb pdb:6QEL|rcsb pdb:6QEM go:"GO:0006270"(DNA replication initiation)|go:"GO:0003697"(single-stranded DNA binding) - - figure legend:Fig. 3, 4, 6, 8|comment:DnaC and PriC form very weak interactions with the other primosome proteins.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/11 2014/10/16 rogid:czmOnQQpFov7eFmCjLGjNhkbJ7M83333 rogid:JuiZiIQR0NdZ0Dm8/F/baTwL89A83333 intact-crc:2A1EE41160614503|rigid:yY3TLw30SyWLmcRv1PT+CGL9VpM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P0ACB0 uniprotkb:P0ABS5 intact:EBI-548978|uniprotkb:P03005|uniprotkb:Q2M6Q2|ensemblbacteria:AAC77022|ensemblbacteria:BAE78054 intact:EBI-549259|uniprotkb:P02922|uniprotkb:P02923|uniprotkb:Q2M9D9|uniprotkb:Q47613|ensemblbacteria:AAC76102|ensemblbacteria:BAE77117 psi-mi:dnab_ecoli(display_long)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpA(gene name synonym)|uniprotkb:b4052(locus name)|uniprotkb:JW4012(locus name) psi-mi:dnag_ecoli(display_long)|uniprotkb:dnaG(gene name)|psi-mi:dnaG(display_short)|uniprotkb:dnaP(gene name synonym)|uniprotkb:parB(gene name synonym)|uniprotkb:b3066(locus name)|uniprotkb:JW3038(locus name) psi-mi:"MI:0071"(molecular sieving) Ng et al. (1996) imex:IM-18709|pubmed:8663105 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6556816|imex:IM-18709-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_418476.1|refseq:WP_000918363.1|dip:DIP-9456N|ensemblbacteria:AAC77022(transcript)|ensemblbacteria:b4052(gene)|ensemblbacteria:BAE78054(gene)|ensemblbacteria:BAE78054(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|interpro:IPR027417|interpro:IPR036185|rcsb pdb:1B79|rcsb pdb:1JWE|rcsb pdb:6BBM|rcsb pdb:6KZA|rcsb pdb:6QEL|rcsb pdb:6QEM refseq:NP_417538.1|refseq:WP_000918827.1|dip:DIP-47954N|interpro:IPR034151|interpro:IPR036977|interpro:IPR037068|rcsb pdb:1DD9|rcsb pdb:1DDE|rcsb pdb:1EQN|rcsb pdb:1T3W|rcsb pdb:2HAJ|rcsb pdb:3B39|rcsb pdb:6CBR|rcsb pdb:6CBS|rcsb pdb:6CBT|interpro:IPR030846|ensemblbacteria:AAC76102(transcript)|ensemblbacteria:b3066(gene)|ensemblbacteria:BAE77117(gene)|ensemblbacteria:BAE77117(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0008270"(zinc ion binding)|go:"GO:1990077"(primosome complex)|interpro:IPR002694(Zinc finger, CHC2-type)|interpro:IPR006171(TOPRIM)|interpro:IPR006295(DNA primase, DnaG)|interpro:IPR013173(DNA primase DnaG, DnaB-binding)|interpro:IPR013264(DNA primase, catalytic core, N-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|interpro:IPR019475 go:"GO:0006270"(DNA replication initiation)|go:"GO:0003697"(single-stranded DNA binding) - crc64:294CF020E7B45D94 figure legend:Fig. 3, 4, 6, 8|comment:DnaC and PriC form very weak interactions with the other primosome proteins.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/11 2014/10/16 rogid:czmOnQQpFov7eFmCjLGjNhkbJ7M83333 rogid:r+ZZ9MEDa7822vsOgSXZk+mSGao83333 intact-crc:2A1EE41160614503|rigid:yY3TLw30SyWLmcRv1PT+CGL9VpM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P0ACB0 uniprotkb:P0A8J2 intact:EBI-548978|uniprotkb:P03005|uniprotkb:Q2M6Q2|ensemblbacteria:AAC77022|ensemblbacteria:BAE78054 intact:EBI-549621|uniprotkb:P07904|uniprotkb:Q2M5V4|ensemblbacteria:AAC77318|ensemblbacteria:BAE78352 psi-mi:dnab_ecoli(display_long)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpA(gene name synonym)|uniprotkb:b4052(locus name)|uniprotkb:JW4012(locus name) psi-mi:dnat_ecoli(display_long)|uniprotkb:dnaT(gene name)|psi-mi:dnaT(display_short)|uniprotkb:b4362(locus name)|uniprotkb:JW4326(locus name)|uniprotkb:Primosomal protein I(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Ng et al. (1996) imex:IM-18709|pubmed:8663105 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6556816|imex:IM-18709-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_418476.1|refseq:WP_000918363.1|dip:DIP-9456N|ensemblbacteria:AAC77022(transcript)|ensemblbacteria:b4052(gene)|ensemblbacteria:BAE78054(gene)|ensemblbacteria:BAE78054(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|interpro:IPR027417|interpro:IPR036185|rcsb pdb:1B79|rcsb pdb:1JWE|rcsb pdb:6BBM|rcsb pdb:6KZA|rcsb pdb:6QEL|rcsb pdb:6QEM refseq:NP_418782.1|refseq:WP_000098818.1|dip:DIP-47957N|ensemblbacteria:AAC77318(transcript)|ensemblbacteria:b4362(gene)|ensemblbacteria:BAE78352(gene)|ensemblbacteria:BAE78352(transcript)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0042802"(identical protein binding)|go:"GO:1990077"(primosome complex)|interpro:IPR020917|interpro:IPR040480|rcsb pdb:2RU8|rcsb pdb:4OU6|rcsb pdb:4OU7 go:"GO:0006270"(DNA replication initiation)|go:"GO:0003697"(single-stranded DNA binding) - crc64:8DE048A3B2A6235B figure legend:Fig. 3, 4, 6, 8|comment:DnaC and PriC form very weak interactions with the other primosome proteins.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/11 2014/10/16 rogid:czmOnQQpFov7eFmCjLGjNhkbJ7M83333 rogid:Ca5J+AWjsjBGNNpTU2itH6zmSZc83333 intact-crc:2A1EE41160614503|rigid:yY3TLw30SyWLmcRv1PT+CGL9VpM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P0ACB0 uniprotkb:P17888 intact:EBI-548978|uniprotkb:P03005|uniprotkb:Q2M6Q2|ensemblbacteria:AAC77022|ensemblbacteria:BAE78054 intact:EBI-552050|uniprotkb:Q2M8N1|ensemblbacteria:AAC76917|ensemblbacteria:BAE77375 psi-mi:dnab_ecoli(display_long)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpA(gene name synonym)|uniprotkb:b4052(locus name)|uniprotkb:JW4012(locus name) psi-mi:pria_ecoli(display_long)|uniprotkb:priA(gene name)|psi-mi:priA(display_short)|uniprotkb:b3935(locus name)|uniprotkb:Replication factor Y(gene name synonym)|uniprotkb:JW3906(locus name)|uniprotkb:ATP-dependent helicase PriA(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Ng et al. (1996) imex:IM-18709|pubmed:8663105 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6556816|imex:IM-18709-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_418476.1|refseq:WP_000918363.1|dip:DIP-9456N|ensemblbacteria:AAC77022(transcript)|ensemblbacteria:b4052(gene)|ensemblbacteria:BAE78054(gene)|ensemblbacteria:BAE78054(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|interpro:IPR027417|interpro:IPR036185|rcsb pdb:1B79|rcsb pdb:1JWE|rcsb pdb:6BBM|rcsb pdb:6KZA|rcsb pdb:6QEL|rcsb pdb:6QEM refseq:NP_418370.1|refseq:WP_001301269.1|dip:DIP-10562N|ensemblbacteria:AAC76917(transcript)|ensemblbacteria:b3935(gene)|ensemblbacteria:BAE77375(gene)|ensemblbacteria:BAE77375(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006276"(plasmid maintenance)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990077"(primosome complex)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR005259(Primosomal protein n)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR040498|interpro:IPR041222|interpro:IPR041236|interpro:IPR042115|rcsb pdb:2D7E|rcsb pdb:2D7G|rcsb pdb:2D7H|rcsb pdb:2DWL|rcsb pdb:2DWM|rcsb pdb:2DWN|rcsb pdb:6DCR go:"GO:0006270"(DNA replication initiation)|go:"GO:0003697"(single-stranded DNA binding) - - figure legend:Fig. 3, 4, 6, 8|comment:DnaC and PriC form very weak interactions with the other primosome proteins.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/11 2014/10/16 rogid:czmOnQQpFov7eFmCjLGjNhkbJ7M83333 rogid:QD9LmjaQ1XsaW1D5sdGnrHTihgQ83333 intact-crc:2A1EE41160614503|rigid:yY3TLw30SyWLmcRv1PT+CGL9VpM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P0ACB0 uniprotkb:P07013 intact:EBI-548978|uniprotkb:P03005|uniprotkb:Q2M6Q2|ensemblbacteria:AAC77022|ensemblbacteria:BAE78054 intact:EBI-1125223|uniprotkb:Q2M6A4|ensemblbacteria:AAC77158|ensemblbacteria:BAE78202 psi-mi:dnab_ecoli(display_long)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpA(gene name synonym)|uniprotkb:b4052(locus name)|uniprotkb:JW4012(locus name) psi-mi:prib_ecoli(display_long)|uniprotkb:priB(gene name)|psi-mi:priB(display_short)|uniprotkb:b4201(locus name)|uniprotkb:JW4159(locus name) psi-mi:"MI:0071"(molecular sieving) Ng et al. (1996) imex:IM-18709|pubmed:8663105 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6556816|imex:IM-18709-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_418476.1|refseq:WP_000918363.1|dip:DIP-9456N|ensemblbacteria:AAC77022(transcript)|ensemblbacteria:b4052(gene)|ensemblbacteria:BAE78054(gene)|ensemblbacteria:BAE78054(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|interpro:IPR027417|interpro:IPR036185|rcsb pdb:1B79|rcsb pdb:1JWE|rcsb pdb:6BBM|rcsb pdb:6KZA|rcsb pdb:6QEL|rcsb pdb:6QEM refseq:NP_418622.1|refseq:WP_001315977.1|ensemblbacteria:b4201(gene)|ensemblbacteria:BAE78202(gene)|ensemblbacteria:BAE78202(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006276"(plasmid maintenance)|go:"GO:0009314"(response to radiation)|go:"GO:0042802"(identical protein binding)|go:"GO:1990099"(pre-primosome complex)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR023646|rcsb pdb:1TXY|rcsb pdb:1V1Q|rcsb pdb:1WOC|rcsb pdb:2CCZ|rcsb pdb:2PNH|rcsb pdb:5WQV|ensemblbacteria:AAC77158(transcript)|dip:DIP-10563N go:"GO:0006270"(DNA replication initiation)|go:"GO:0003697"(single-stranded DNA binding) - - figure legend:Fig. 3, 4, 6, 8|comment:DnaC and PriC form very weak interactions with the other primosome proteins.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/11 2014/10/16 rogid:czmOnQQpFov7eFmCjLGjNhkbJ7M83333 rogid:t9m94Sm9Zz1cXCqAybm67nkDNRQ83333 intact-crc:2A1EE41160614503|rigid:yY3TLw30SyWLmcRv1PT+CGL9VpM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P0ACB0 uniprotkb:P23862 intact:EBI-548978|uniprotkb:P03005|uniprotkb:Q2M6Q2|ensemblbacteria:AAC77022|ensemblbacteria:BAE78054 intact:EBI-1117383|uniprotkb:Q2MBW0|ensemblbacteria:AAC73569|ensemblbacteria:BAE76246 psi-mi:dnab_ecoli(display_long)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpA(gene name synonym)|uniprotkb:b4052(locus name)|uniprotkb:JW4012(locus name) psi-mi:pric_ecoli(display_long)|uniprotkb:priC(gene name)|psi-mi:priC(display_short)|uniprotkb:b0467(locus name)|uniprotkb:JW0456(locus name) psi-mi:"MI:0071"(molecular sieving) Ng et al. (1996) imex:IM-18709|pubmed:8663105 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6556816|imex:IM-18709-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_418476.1|refseq:WP_000918363.1|dip:DIP-9456N|ensemblbacteria:AAC77022(transcript)|ensemblbacteria:b4052(gene)|ensemblbacteria:BAE78054(gene)|ensemblbacteria:BAE78054(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|interpro:IPR027417|interpro:IPR036185|rcsb pdb:1B79|rcsb pdb:1JWE|rcsb pdb:6BBM|rcsb pdb:6KZA|rcsb pdb:6QEL|rcsb pdb:6QEM ensemblbacteria:AAC73569(transcript)|ensemblbacteria:b0467(gene)|ensemblbacteria:BAE76246(gene)|ensemblbacteria:BAE76246(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:1990077"(primosome complex)|interpro:IPR010890(Primosomal replication priB and priC)|interpro:IPR038338|rcsb pdb:2RT6|refseq:WP_000844874.1|refseq:NP_415000.1|dip:DIP-10564N go:"GO:0006270"(DNA replication initiation)|go:"GO:0003697"(single-stranded DNA binding) - - figure legend:Fig. 3, 4, 6, 8|comment:DnaC and PriC form very weak interactions with the other primosome proteins.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/11 2014/10/16 rogid:czmOnQQpFov7eFmCjLGjNhkbJ7M83333 rogid:7vsr929ivZk++tx1fxgUnL1NNaA83333 intact-crc:2A1EE41160614503|rigid:yY3TLw30SyWLmcRv1PT+CGL9VpM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)