#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P00766 uniprotkb:P10184 intact:EBI-6664027 intact:EBI-6663991|ensembl:ENSGALP00000005535|uniprotkb:A0A3Q2UJ85|uniprotkb:F1NMN2|uniprotkb:Q6XLT0 psi-mi:ctra_bovin(display_long) psi-mi:iov7_chick(display_long)|uniprotkb:SPINK5(gene name)|psi-mi:SPINK5(display_short)|uniprotkb:OIH(gene name synonym)|uniprotkb:Serine protease inhibitor Kazal-type 5(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Gertler et al. (1980) pubmed:6904299|imex:IM-25951 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-6664021|imex:IM-25951-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0007586"(digestion)|go:"GO:0097180"(serine protease inhibitor complex)|go:"GO:0097655"(serpin family protein binding)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|go:"GO:0004252"(serine-type endopeptidase activity)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|go:"GO:0005615"(extracellular space)|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504|go:"GO:0006508"(proteolysis)|rcsb pdb:1AB9|rcsb pdb:1ACB|rcsb pdb:1AFQ|rcsb pdb:1CA0|rcsb pdb:1CBW|rcsb pdb:1CGI|rcsb pdb:1CGJ|rcsb pdb:1CHG|rcsb pdb:1CHO|rcsb pdb:1DLK|rcsb pdb:1EX3|rcsb pdb:1GCD|rcsb pdb:1GCT|rcsb pdb:1GG6|rcsb pdb:1GGD|rcsb pdb:1GHA|rcsb pdb:1GHB|rcsb pdb:1GL0|rcsb pdb:1GL1|rcsb pdb:1GMC|rcsb pdb:1GMD|rcsb pdb:1GMH|rcsb pdb:1HJA|rcsb pdb:1K2I|rcsb pdb:1MTN|rcsb pdb:1N8O|rcsb pdb:1OXG|rcsb pdb:1P2M|rcsb pdb:1P2N|rcsb pdb:1P2O|rcsb pdb:1P2Q|rcsb pdb:1T7C|rcsb pdb:1T8L|rcsb pdb:1T8M|rcsb pdb:1T8N|rcsb pdb:1T8O|rcsb pdb:1VGC|rcsb pdb:1YPH|rcsb pdb:2CGA|rcsb pdb:2CHA|rcsb pdb:2GCH|rcsb pdb:2GCT|rcsb pdb:2VGC|rcsb pdb:2Y6T|rcsb pdb:2GMT|rcsb pdb:3BG4|rcsb pdb:3GCH|rcsb pdb:3GCT|rcsb pdb:3RU4|rcsb pdb:3T62|rcsb pdb:2P8O|rcsb pdb:3VGC|rcsb pdb:4CHA|rcsb pdb:4GCH|rcsb pdb:4Q2K|rcsb pdb:4VGC|rcsb pdb:5CHA|rcsb pdb:5GCH|rcsb pdb:5J4Q|rcsb pdb:5J4S|rcsb pdb:6CHA|rcsb pdb:6GCH|rcsb pdb:7GCH|rcsb pdb:7KTY|rcsb pdb:7KTZ|rcsb pdb:7KU0|rcsb pdb:7KU1|rcsb pdb:7KU2|rcsb pdb:7KU3|rcsb pdb:8GCH|dip:DIP-6068N ensembl:ENSGALG00000031496(gene)|ensembl:ENSGALT00000005545(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008200"(ion channel inhibitor activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0030414"(peptidase inhibitor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0051412"(response to corticosterone)|interpro:IPR002350(Proteinase inhibitor I1, Kazal)|interpro:IPR036058 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/05/06 2020/06/18 rogid:EjOlpE0S5b8sCcON1Jy3W9SjLKs9913 rogid:zqXZ9awpgSM5OhffAd4Eiyzh0vI9031 intact-crc:D1787DED3BD12AB9|rigid:tMPZfbjkkwLXUXzbMPHCPujfO6c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10184 uniprotkb:P00766 intact:EBI-6663991|ensembl:ENSGALP00000005535|uniprotkb:A0A3Q2UJ85|uniprotkb:F1NMN2|uniprotkb:Q6XLT0 intact:EBI-6664027 psi-mi:iov7_chick(display_long)|uniprotkb:SPINK5(gene name)|psi-mi:SPINK5(display_short)|uniprotkb:OIH(gene name synonym)|uniprotkb:Serine protease inhibitor Kazal-type 5(gene name synonym) psi-mi:ctra_bovin(display_long) psi-mi:"MI:0982"(electrophoretic mobility-based method) Gertler et al. (1980) pubmed:6904299|imex:IM-25951 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-6664114|imex:IM-25951-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSGALG00000031496(gene)|ensembl:ENSGALT00000005545(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008200"(ion channel inhibitor activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0030414"(peptidase inhibitor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0051412"(response to corticosterone)|interpro:IPR002350(Proteinase inhibitor I1, Kazal)|interpro:IPR036058 go:"GO:0007586"(digestion)|go:"GO:0097180"(serine protease inhibitor complex)|go:"GO:0097655"(serpin family protein binding)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|go:"GO:0004252"(serine-type endopeptidase activity)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|go:"GO:0005615"(extracellular space)|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504|go:"GO:0006508"(proteolysis)|rcsb pdb:1AB9|rcsb pdb:1ACB|rcsb pdb:1AFQ|rcsb pdb:1CA0|rcsb pdb:1CBW|rcsb pdb:1CGI|rcsb pdb:1CGJ|rcsb pdb:1CHG|rcsb pdb:1CHO|rcsb pdb:1DLK|rcsb pdb:1EX3|rcsb pdb:1GCD|rcsb pdb:1GCT|rcsb pdb:1GG6|rcsb pdb:1GGD|rcsb pdb:1GHA|rcsb pdb:1GHB|rcsb pdb:1GL0|rcsb pdb:1GL1|rcsb pdb:1GMC|rcsb pdb:1GMD|rcsb pdb:1GMH|rcsb pdb:1HJA|rcsb pdb:1K2I|rcsb pdb:1MTN|rcsb pdb:1N8O|rcsb pdb:1OXG|rcsb pdb:1P2M|rcsb pdb:1P2N|rcsb pdb:1P2O|rcsb pdb:1P2Q|rcsb pdb:1T7C|rcsb pdb:1T8L|rcsb pdb:1T8M|rcsb pdb:1T8N|rcsb pdb:1T8O|rcsb pdb:1VGC|rcsb pdb:1YPH|rcsb pdb:2CGA|rcsb pdb:2CHA|rcsb pdb:2GCH|rcsb pdb:2GCT|rcsb pdb:2VGC|rcsb pdb:2Y6T|rcsb pdb:2GMT|rcsb pdb:3BG4|rcsb pdb:3GCH|rcsb pdb:3GCT|rcsb pdb:3RU4|rcsb pdb:3T62|rcsb pdb:2P8O|rcsb pdb:3VGC|rcsb pdb:4CHA|rcsb pdb:4GCH|rcsb pdb:4Q2K|rcsb pdb:4VGC|rcsb pdb:5CHA|rcsb pdb:5GCH|rcsb pdb:5J4Q|rcsb pdb:5J4S|rcsb pdb:6CHA|rcsb pdb:6GCH|rcsb pdb:7GCH|rcsb pdb:7KTY|rcsb pdb:7KTZ|rcsb pdb:7KU0|rcsb pdb:7KU1|rcsb pdb:7KU2|rcsb pdb:7KU3|rcsb pdb:8GCH|dip:DIP-6068N - - - figure legend:2 and 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/05/06 2020/06/18 rogid:zqXZ9awpgSM5OhffAd4Eiyzh0vI9031 rogid:EjOlpE0S5b8sCcON1Jy3W9SjLKs9913 intact-crc:8F530CBC1A603FEC|rigid:tMPZfbjkkwLXUXzbMPHCPujfO6c false - - 1 2 psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining)