#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O15530-4 uniprotkb:Q8IUH5 intact:EBI-9087775|ensembl:ENSP00000268673 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:o15530-4(display_long)|uniprotkb:PDK1(gene name synonym)|uniprotkb:PDPK1(gene name)|psi-mi:PDPK1(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9087772|imex:IM-21827-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-717097(isoform-parent)|ensembl:ENSG00000140992(gene)|ensembl:ENST00000268673(transcript)|uniprotkb:O15530-4(isoform-parent)|uniprotkb:O15530-4(identity)|entrezgene/locuslink:5170(identity)|ddbj/embl/genbank:BC033494(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:xpGOPsJyFONnxfu4HaGOV4BLjX09606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:B8AE29491D33676A|rigid:x3pKmPRr055h9hs4u1wbIgXavzo false - sufficient binding region:64-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:O14744 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-351098|uniprotkb:Q6IBR1|uniprotkb:A8MZ91|uniprotkb:Q9UKH1|uniprotkb:B5BU10|uniprotkb:D3DS33|ensembl:ENSP00000319169|uniprotkb:A8MTP3|uniprotkb:B4DX49|uniprotkb:B4DY30|uniprotkb:E2QRE7 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:anm5_human(display_long)|uniprotkb:PRMT5(gene name)|psi-mi:PRMT5(display_short)|uniprotkb:IBP72(gene name synonym)|uniprotkb:JBP1(gene name synonym)|uniprotkb:HRMT1L5(gene name synonym)|uniprotkb:Shk1 kinase-binding protein 1 homolog(gene name synonym)|uniprotkb:Jak-binding protein 1(gene name synonym)|uniprotkb:72 kDa ICln-binding protein(gene name synonym)|uniprotkb:SKB1(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT5(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9087757|imex:IM-21827-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_001034708.1|refseq:NP_006100.2|refseq:NP_001269882.1|refseq:NP_001269884.1|refseq:NP_001269885.1|ensembl:ENSG00000100462(gene)|ensembl:ENST00000324366(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000785"(chromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0018216"(peptidyl-arginine methylation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034709"(methylosome)|go:"GO:0034969"(histone arginine methylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035243"(protein-arginine omega-N symmetric methyltransferase activity)|go:"GO:0035246"(peptidyl-arginine N-methylation)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043985"(histone H4-R3 methylation)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070888"(E-box binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0097421"(liver regeneration)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR007857(Skb1 methyltransferase)|interpro:IPR025799|interpro:IPR029063|interpro:IPR035075|interpro:IPR035247|interpro:IPR035248|mint:O14744|rcsb pdb:4GQB|rcsb pdb:4X60|rcsb pdb:4X61|rcsb pdb:4X63|rcsb pdb:5C9Z|rcsb pdb:5EMJ|rcsb pdb:5EMK|rcsb pdb:5EML|rcsb pdb:5EMM|rcsb pdb:5FA5|rcsb pdb:6CKC|rcsb pdb:6K1S|rcsb pdb:6RLL|rcsb pdb:6RLQ|rcsb pdb:6UGH|rcsb pdb:6UXX|rcsb pdb:6UXY|rcsb pdb:6V0N|rcsb pdb:6V0O|rcsb pdb:6V0P|rcsb pdb:7KIB|rcsb pdb:7KIC|rcsb pdb:7KID|rcsb pdb:7L1G|rcsb pdb:7M05|reactome:R-HSA-191859|reactome:R-HSA-3214858|reactome:R-HSA-6804760|go:"GO:1904992"(positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway)|dip:DIP-33172N|uniprotkb:O14744(identity)|ddbj/embl/genbank:BC025979(identity)|entrezgene/locuslink:10419(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:EwePjCDiU/fiuKOO+wnoYQ8I57I9606 intact-crc:CBA1366CA9E1F2A8|rigid:CpyweTFqzteWAt/MEI7hKXz+S1M false sufficient binding region:64-257("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:O60259 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-3915857|uniprotkb:Q5V9X1|uniprotkb:Q5V9X2|uniprotkb:Q9UQ47|uniprotkb:Q9HCB3|uniprotkb:Q9NR69|uniprotkb:Q8IW69|uniprotkb:Q9UIL9|uniprotkb:Q9NR68|ensembl:ENSP00000472016 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:klk8_human(display_long)|uniprotkb:KLK8(gene name)|psi-mi:KLK8(display_short)|uniprotkb:NRPN(gene name synonym)|uniprotkb:PRSS19(gene name synonym)|uniprotkb:TADG14(gene name synonym)|uniprotkb:Neuropsin(gene name synonym)|uniprotkb:Ovasin(gene name synonym)|uniprotkb:Serine protease 19(gene name synonym)|uniprotkb:Serine protease TADG-14(gene name synonym)|uniprotkb:Tumor-associated differentially expressed gene 14 protein(gene name synonym)|uniprotkb:UNQ283/PRO322(orf name) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9087791|imex:IM-21827-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_009127.1|refseq:NP_653088.1|refseq:NP_653089.1|refseq:NP_653090.1|refseq:NP_001268360.1|ensembl:ENSG00000129455(gene)|ensembl:ENST00000600767(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0007613"(memory)|go:"GO:0008219"(cell death)|go:"GO:0009611"(response to wounding)|go:"GO:0030141"(secretory granule)|go:"GO:0031642"(negative regulation of myelination)|go:"GO:0043616"(keratinocyte proliferation)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0050808"(synapse organization)|go:"GO:0097180"(serine protease inhibitor complex)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504|rcsb pdb:5MS3|rcsb pdb:5MS4|reactome:R-HSA-6809371|uniprotkb:O60259(identity)|entrezgene/locuslink:11202(identity)|ddbj/embl/genbank:BC040887(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:uWjD9cViyVX9pl6mWgGUT6SF14s9606 intact-crc:FEEA44B6F2B32200|rigid:JAQqC2992j3L6890HJaSYJkoqRE false sufficient binding region:64-257("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:O95416 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9087806|uniprotkb:Q3KPH7|uniprotkb:B2RAC0|ensembl:ENSP00000305343 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:sox14_human(display_long)|uniprotkb:Protein SOX-28(gene name synonym)|uniprotkb:SOX28(gene name synonym)|uniprotkb:SOX14(gene name)|psi-mi:SOX14(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9087812|imex:IM-21827-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_004180.1|ensembl:ENSG00000168875(gene)|ensembl:ENST00000306087(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0009649"(entrainment of circadian clock)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2001222"(regulation of neuron migration)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR029549|interpro:IPR036910|uniprotkb:O95416(identity)|ddbj/embl/genbank:BC106730(identity)|entrezgene/locuslink:8403(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:uxTUpInLsdNNlNFLhEvpU3iNOvY9606 intact-crc:514A4A36BBAF0C56|rigid:6QiR1GQdRMcTQ0n5I554rKOtjvw false sufficient binding region:64-257("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P48730-2 uniprotkb:Q8IUH5 intact:EBI-9087876|ensembl:ENSP00000376146 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:p48730-2(display_long)|uniprotkb:HCKID(gene name synonym)|uniprotkb:Tau-protein kinase CSNK1D(gene name synonym)|uniprotkb:CSNK1D(gene name)|psi-mi:CSNK1D(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9087880|imex:IM-21827-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-751621(isoform-parent)|ensembl:ENSG00000141551(gene)|ensembl:ENST00000392334(transcript)|uniprotkb:P48730-2(isoform-parent)|uniprotkb:P48730-2(identity)|ddbj/embl/genbank:BC015775(identity)|entrezgene/locuslink:1453(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:DKYeQTtdg+u5Gm9wscDkiTs7Blg9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:93D0D47EC2785E9C|rigid:yI9cncQsphvllXDDNHnH3oz7OZ8 false - sufficient binding region:64-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02792 uniprotkb:Q8IUH5 intact:EBI-713279|uniprotkb:Q7Z2W1|uniprotkb:Q9BTZ8|ensembl:ENSP00000366525|uniprotkb:B2R4B9|uniprotkb:Q6IBT7|uniprotkb:Q86WI9|uniprotkb:Q8WU07|uniprotkb:Q96AU9|uniprotkb:Q96CU0 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:fril_human(display_long)|uniprotkb:FTL(gene name)|psi-mi:FTL(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9087842|imex:IM-21827-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000137.2|ensembl:ENSG00000087086(gene)|ensembl:ENST00000331825(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006880"(intracellular sequestering of iron ion)|go:"GO:0008043"(intracellular ferritin complex)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008199"(ferric iron binding)|go:"GO:0016020"(membrane)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0044754"(autolysosome)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001519(Ferritin, N-terminal)|interpro:IPR008331(Ferritin and Dps)|interpro:IPR009040(Ferritin-like)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR012347(Ferritin-related)|interpro:IPR014034(Ferritin, conserved site)|mint:P02792|rcsb pdb:2FFX|rcsb pdb:2FG4|rcsb pdb:2FG8|rcsb pdb:3KXU|rcsb pdb:4V6B|rcsb pdb:5LG8|rcsb pdb:6TR9|rcsb pdb:6TS0|rcsb pdb:6TS1|rcsb pdb:6TSA|rcsb pdb:6TSF|rcsb pdb:6TSJ|rcsb pdb:6WX6|reactome:R-HSA-3000480|reactome:R-HSA-432722|reactome:R-HSA-6798695|reactome:R-HSA-917937|dip:DIP-31248N|uniprotkb:P02792(identity)|ddbj/embl/genbank:BC004245(identity)|entrezgene/locuslink:2512(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:+mbnoETQ9TuBZg8Gc09nwAjwKTE9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:86FE2C429CB4255C|rigid:U2ZD2NceucT1eWVtki54ylpsGG8 false - sufficient binding region:64-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:O95881 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-2564581|uniprotkb:B3KQS0|uniprotkb:Q5T1T4|uniprotkb:Q96H50|ensembl:ENSP00000360688 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:txd12_human(display_long)|uniprotkb:TXNDC12(gene name)|psi-mi:TXNDC12(display_short)|uniprotkb:TLP19(gene name synonym)|uniprotkb:Thioredoxin-like protein p19(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 19(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 18(gene name synonym)|uniprotkb:hTLP19(gene name synonym)|uniprotkb:UNQ713/PRO1376(orf name) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9087827|imex:IM-21827-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_056997.1|ensembl:ENSG00000117862(gene)|ensembl:ENST00000371626(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0019153"("protein-disulfide reductase (glutathione) activity")|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|interpro:IPR037462|rcsb pdb:1SEN|rcsb pdb:2K8V|uniprotkb:O95881(identity)|ddbj/embl/genbank:BC001493(identity)|entrezgene/locuslink:51060(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:lgsrfn2RsfqJlKY0WWgUnvmMImM9606 intact-crc:1FD033D62EEFF49D|rigid:L9WHLTdDjucQBNClW/WhJdeZ9UU false sufficient binding region:64-257("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32243-2 uniprotkb:Q8IUH5 intact:EBI-9087860|ensembl:ENSP00000500115|ensembl:ENSP00000500595 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:p32243-2(display_long)|uniprotkb:Orthodenticle homolog 2(gene name synonym)|uniprotkb:OTX2(gene name)|psi-mi:OTX2(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9087857|imex:IM-21827-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-954480(isoform-parent)|uniprotkb:P32243-2(isoform-parent)|ensembl:ENSG00000165588(gene)|ensembl:ENST00000672264(transcript)|ensembl:ENST00000673481(transcript)|uniprotkb:P32243-2(identity)|ddbj/embl/genbank:BC032579(identity)|entrezgene/locuslink:5015(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:hSsSmMeopu45uUaU7eOiHa1EtUE9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:E7714BA4B4D58E4F|rigid:Ad8KdumnUqKchFI9wJCFM2+WGD4 false - sufficient binding region:64-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P60228 uniprotkb:Q8IUH5 intact:EBI-347740|uniprotkb:O43902|uniprotkb:Q64058|uniprotkb:Q64059|uniprotkb:Q64252|uniprotkb:Q8WVK4|intact:EBI-1237448|uniprotkb:Q6FG33|ensembl:ENSP00000220849 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:eif3e_human(display_long)|uniprotkb:EIF3E(gene name)|psi-mi:EIF3E(display_short)|uniprotkb:INT6(gene name synonym)|uniprotkb:EIF3S6(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 6(gene name synonym)|uniprotkb:eIF-3 p48(gene name synonym)|uniprotkb:Viral integration site protein INT-6 homolog(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9087909|imex:IM-21827-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001559.1|ensembl:ENSG00000104408(gene)|ensembl:ENST00000220849(transcript)|dip:DIP-32691N|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0016605"(PML body)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071540"(eukaryotic translation initiation factor 3 complex, eIF3e)|go:"GO:1902416"(positive regulation of mRNA binding)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR016650(Translation initiation factor 3, subunit 6, eukaryotic)|interpro:IPR019010|interpro:IPR036390|mint:P60228|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6FEC|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|uniprotkb:P60228(identity)|entrezgene/locuslink:3646(identity)|ddbj/embl/genbank:BC008419(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:s09LicCa0mb9WwO7esZvVdvUonY9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:81907BB53F7957B3|rigid:ETHBbAOKTOtXo+M7ObTltuArKpc false - sufficient binding region:64-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08170 uniprotkb:Q8IUH5 intact:EBI-722621|uniprotkb:Q5VXP1|uniprotkb:Q9BUA4|ensembl:ENSP00000362900|uniprotkb:Q9UEB5 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:srsf4_human(display_long)|uniprotkb:Pre-mRNA-splicing factor SRP75(gene name synonym)|uniprotkb:SRP001LB(gene name synonym)|uniprotkb:SFRS4(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 4(gene name synonym)|uniprotkb:SRSF4(gene name)|psi-mi:SRSF4(display_short)|uniprotkb:SRP75(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9087939|imex:IM-21827-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005617.2|ensembl:ENSG00000116350(gene)|ensembl:ENST00000373795(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0032868"(response to insulin)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:1990825"(sequence-specific mRNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035585|interpro:IPR035979|mint:Q08170|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|uniprotkb:Q08170(identity)|ddbj/embl/genbank:BC002781(identity)|entrezgene/locuslink:6429(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:LVIhOlsJ8rUYB68fWFDsovUGTeU9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:EF6055A62A44D8A9|rigid:ZuL2Q2Ni0FaOrrPWPTWPMDu70ag false - sufficient binding region:64-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q06609 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-297202|uniprotkb:Q6FHX9|ensembl:ENSP00000267868|ensembl:ENSP00000433924|uniprotkb:B0FXP0|uniprotkb:Q9BV60|intact:EBI-1059207|uniprotkb:B2R8T6|uniprotkb:Q6ZNA8 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:rad51_human(display_long)|uniprotkb:RAD51(gene name)|psi-mi:RAD51(display_short)|uniprotkb:RAD51A(gene name synonym)|uniprotkb:RECA(gene name synonym)|uniprotkb:RAD51 homolog A(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9087924|imex:IM-21827-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020587|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|mint:Q06609|rcsb pdb:1B22|rcsb pdb:1N0W|rcsb pdb:5H1B|rcsb pdb:5H1C|rcsb pdb:5JZC|rcsb pdb:5NP7|rcsb pdb:5NWL|rcsb pdb:7C9A|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|reactome:R-HSA-8953750|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0042148"(strand invasion)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051106"(positive regulation of DNA ligation)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0072719"(cellular response to cisplatin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072757"(cellular response to camptothecin)|go:"GO:1904631"(response to glucoside)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|go:"GO:1990426"(mitotic recombination-dependent replication fork processing)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010995(DNA repair Rad51/transcription factor NusA, alpha-helical)|interpro:IPR011941(DNA repair protein RAD51)|ensembl:ENSG00000051180(gene)|ensembl:ENST00000267868(transcript)|ensembl:ENST00000532743(transcript)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000800"(lateral element)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006312"(mitotic recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016605"(PML body)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0005815"(microtubule organizing center)|refseq:NP_001157742.1|refseq:NP_002866.2|refseq:NP_597994.3|refseq:XP_011520159.1|refseq:XP_011520160.1|refseq:XP_011520161.1|refseq:XP_011520162.1|refseq:XP_011520163.1|refseq:NP_001157741.1|refseq:XP_006720689.1|dip:DIP-462N|uniprotkb:Q06609(identity)|entrezgene/locuslink:5888(identity)|ddbj/embl/genbank:CR536559(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:B7WPMU7tZuNcA2qjsTR+7i/OwFw9606 intact-crc:6D4988E39FB5FEC3|rigid:yHQzzLqX9GaLSy/UzAu38QyOOpg false sufficient binding region:64-257("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P55145 uniprotkb:Q8IUH5 intact:EBI-1044104|uniprotkb:Q14CX4|uniprotkb:Q86U67|uniprotkb:Q96IS4|ensembl:ENSP00000432799 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:manf_human(display_long)|uniprotkb:Protein ARMET(gene name synonym)|uniprotkb:ARMET(gene name synonym)|uniprotkb:ARP(gene name synonym)|uniprotkb:MANF(gene name)|psi-mi:MANF(display_short)|uniprotkb:Arginine-rich protein(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9087895|imex:IM-21827-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145050(gene)|ensembl:ENST00000528157(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008083"(growth factor activity)|go:"GO:0031175"(neuron projection development)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0120146"(sulfatide binding)|go:"GO:1905897"(regulation of response to endoplasmic reticulum stress)|interpro:IPR019345|interpro:IPR036361|rcsb pdb:2KVD|rcsb pdb:2KVE|rcsb pdb:2W51|reactome:R-HSA-114608|refseq:NP_006001.4|uniprotkb:P55145(identity)|entrezgene/locuslink:7873(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:6MhPWttVgDJsaGyg0sXn/tBXpCQ9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:64AB0DA81E46561A|rigid:Cr+LzDIMMm1FbaPOarFsgd+I8+E false - sufficient binding region:64-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q13113 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-716063|uniprotkb:Q96EI1|uniprotkb:Q6ICT9|ensembl:ENSP00000294338|ensembl:ENSP00000360952 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:pdz1i_human(display_long)|uniprotkb:MAP17(gene name synonym)|uniprotkb:PDZK1IP1(gene name)|psi-mi:PDZK1IP1(display_short)|uniprotkb:17 kDa membrane-associated protein(gene name synonym)|uniprotkb:Protein DD96(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9087954|imex:IM-21827-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_005755.1|ensembl:ENSG00000162366(gene)|ensembl:ENST00000294338(transcript)|ensembl:ENST00000371885(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR026628|interpro:IPR031627|uniprotkb:Q13113(identity)|entrezgene/locuslink:10158(identity)|ddbj/embl/genbank:BC012303(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:YgaXhe5D8C2g1h5RNDA0PNSxTG89606 intact-crc:DB408C8901930E6B|rigid:hitpSpJvQWefXeXRGQygk7idRxs false sufficient binding region:64-257("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3KNW7 uniprotkb:Q8IUH5 intact:EBI-9087984 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:q3knw7_human(display_long)|uniprotkb:hCG_1820928(orf name)|uniprotkb:FKSG83(gene name)|psi-mi:FKSG83(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9087988|imex:IM-21827-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004072(Vomeronasal receptor, type 1)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016503"(pheromone receptor activity)|go:"GO:0019236"(response to pheromone)|uniprotkb:Q3KNW7(identity)|ddbj/embl/genbank:BC107050(identity)|entrezgene/locuslink:83954(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:ly/d3w3gaE7aYYj4Hhf/bxhdsmo9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:4320EEBFF8B65957|rigid:ESrlhHn2qfLuQE47ewbTnsL9dpE false - sufficient binding region:64-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3SYB3 uniprotkb:Q8IUH5 intact:EBI-6425864|ensembl:ENSP00000484875|uniprotkb:B2RPC4|uniprotkb:Q4V336 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:fx4l6_human(display_long)|uniprotkb:FOXD4L6(gene name)|psi-mi:FOXD4L6(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088003|imex:IM-21827-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000273514(gene)|ensembl:ENST00000622588(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0030154"(cell differentiation)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|refseq:NP_001078945.1|uniprotkb:Q3SYB3(identity)|ddbj/embl/genbank:BC103887(identity)|entrezgene/locuslink:653404(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:WORhNqs8vOXNc5eM2civM28LqbQ9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:6D53DC4DB7C79198|rigid:JsDc7JD1VIxrLHQ/dvA+mkGqLLM false - sufficient binding region:64-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q6ZU52-2 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9088018 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:q6zu52-2(display_long)|uniprotkb:KIAA0408(gene name)|psi-mi:KIAA0408(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088022|imex:IM-21827-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) intact:EBI-739493(isoform-parent)|uniprotkb:Q6ZU52-2(identity)|entrezgene/locuslink:9729(identity)|ddbj/embl/genbank:BC018396(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:FEV07ASyxbvDB6EjUE+sRKAjXT49606 intact-crc:CC28F0702DEDB2A3|rigid:UVklDwV2zoSCu8NNKMmf3vPP4wE false sufficient binding region:64-257("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q13829 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-2505861|uniprotkb:B7Z6M4|uniprotkb:Q5TZQ1|ensembl:ENSP00000226225 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:bacd2_human(display_long)|uniprotkb:BACURD2(gene name synonym)|uniprotkb:BTB/POZ domain-containing protein TNFAIP1(gene name synonym)|uniprotkb:Protein B12(gene name synonym)|uniprotkb:TNFAIP1(gene name)|psi-mi:TNFAIP1(display_short)|uniprotkb:EDP1(gene name synonym)|uniprotkb:Tumor necrosis factor, alpha-induced protein 1, endothelial(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9087969|imex:IM-21827-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_066960.1|ensembl:ENSG00000109079(gene)|ensembl:ENST00000226225(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0016477"(cell migration)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030332"(cyclin binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR011333(BTB/POZ fold)|mint:Q13829|reactome:R-HSA-9696264|reactome:R-HSA-9696270|uniprotkb:Q13829(identity)|ddbj/embl/genbank:BC001643(identity)|entrezgene/locuslink:7126(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:8vM9HnNmkirDbJRETV/TeE8pONY9606 intact-crc:814A0448114BAC1B|rigid:RVVcxxhsRqfjpQRqgwQnYAb5AcU false sufficient binding region:64-257("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUC1 uniprotkb:Q8IUH5 intact:EBI-1052037|uniprotkb:A1L4I8|ensembl:ENSP00000330720 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:kr111_human(display_long)|uniprotkb:High sulfur keratin-associated protein 11.1(gene name synonym)|uniprotkb:KRTAP11-1(gene name)|psi-mi:KRTAP11-1(display_short)|uniprotkb:KAP11.1(gene name synonym)|uniprotkb:KRTAP11.1(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088066|imex:IM-21827-20 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_787054.1|ensembl:ENSG00000182591(gene)|ensembl:ENST00000332378(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|interpro:IPR007951(PMG)|reactome:R-HSA-6805567|uniprotkb:Q8IUC1(identity)|entrezgene/locuslink:337880(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:1gb6A0xMj0b1AuWCeOafAW+VeQk9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:8543F9C64D3F3617|rigid:ZR3296OFvc8+9tuU7Fh3KWxg1r8 false - sufficient binding region:64-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q8TAB5 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-747505|uniprotkb:Q8N8N6|uniprotkb:D3DPS1|ensembl:ENSP00000425166 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:ca216_human(display_long)|uniprotkb:C1orf216(gene name)|psi-mi:C1orf216(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088098|imex:IM-21827-22 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_689587.1|ensembl:ENSG00000142686(gene)|ensembl:ENST00000270815(transcript)|interpro:IPR027812|mint:Q8TAB5|refseq:NP_001335620.1|uniprotkb:Q8TAB5(identity)|ddbj/embl/genbank:BC026909(identity)|entrezgene/locuslink:127703(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:AY/X3DiXpcS0UfG9oTpHUIxtaQw9606 intact-crc:5A43E0E566F975E9|rigid:OcYA2pKLhfM+WxHpnLSKGhXXjLw false sufficient binding region:64-257("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q8NFZ0 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-724767|uniprotkb:Q96K67|uniprotkb:Q96SW7|uniprotkb:Q5JVB1|uniprotkb:Q7Z4Q6|uniprotkb:Q7Z4R0|uniprotkb:Q8N1P5|uniprotkb:Q8N586|uniprotkb:Q96E82|uniprotkb:Q9UFB2|uniprotkb:Q5JVB0|ensembl:ENSP00000355415 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:fbh1_human(display_long)|uniprotkb:FBH1(gene name)|psi-mi:FBH1(display_short)|uniprotkb:F-box only protein 18(gene name synonym)|uniprotkb:FBX18(gene name synonym)|uniprotkb:FBXO18(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088080|imex:IM-21827-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_116196.3|refseq:NP_835363.1|ensembl:ENSG00000134452(gene)|ensembl:ENST00000362091(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000725"(recombinational repair)|go:"GO:0000737"(DNA catabolic process, endonucleolytic)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0048478"(replication fork protection)|go:"GO:0072429"(response to intra-S DNA damage checkpoint signaling)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902231"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|interpro:IPR000212(DNA helicase, UvrD/REP type)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR014017(DNA helicase, UvrD-like, C terminal)|interpro:IPR027417|interpro:IPR036047|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008219"(cell death)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031297"(replication fork processing)|go:"GO:0035562"(negative regulation of chromatin binding)|refseq:NP_001245381.1|refseq:NP_001245382.1|refseq:XP_011518050.1|uniprotkb:Q8NFZ0(identity)|ddbj/embl/genbank:BC032674(identity)|entrezgene/locuslink:84893(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:gHFAJ/6l2s69lfhpp3Uo9/V7VZA9606 intact-crc:6C2D21FC3BF068B8|rigid:qMmUBMNafeGNrxjCIHCyL5F7c/8 false sufficient binding region:64-257("MI:0442") sufficient binding region:264-1043("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7Z403 uniprotkb:Q8IUH5 intact:EBI-9088037|uniprotkb:O43284|uniprotkb:Q8IUI7|uniprotkb:Q8IWU8|uniprotkb:Q9HAG5|uniprotkb:Q8IU98|uniprotkb:Q8TEQ7|uniprotkb:Q45VJ2|ensembl:ENSP00000313408|ensembl:ENSP00000376260|ensembl:ENSP00000465261 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:tmc6_human(display_long)|uniprotkb:EVER1(gene name synonym)|uniprotkb:EVIN1(gene name synonym)|uniprotkb:Epidermodysplasia verruciformis protein 1(gene name synonym)|uniprotkb:Protein LAK-4(gene name synonym)|uniprotkb:TMC6(gene name)|psi-mi:TMC6(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088048|imex:IM-21827-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001120670.1|refseq:NP_009198.4|refseq:XP_005257052.1|refseq:NP_001308114.1|refseq:XP_011522557.1|ensembl:ENSG00000141524(gene)|ensembl:ENST00000322914(transcript)|ensembl:ENST00000392467(transcript)|ensembl:ENST00000590602(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008381"(mechanosensitive ion channel activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|interpro:IPR012496(TMC)|interpro:IPR038900|mint:Q7Z403|reactome:R-HSA-6798695|uniprotkb:Q7Z403(identity)|ddbj/embl/genbank:BC007766(identity)|entrezgene/locuslink:11322(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:+J7INKOidmvYLLYnhFI1J+fwW6w9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:361E681713FD9C3B|rigid:l7ydY0w+fYTwmqwrVpVSLA8rYNY false sufficient binding region:362-572("MI:0442") sufficient binding region:64-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UIJ7 uniprotkb:Q8IUH5 intact:EBI-3916527|uniprotkb:Q5VYW6|uniprotkb:Q9NPB4|uniprotkb:Q9H576|uniprotkb:D3DRI1|uniprotkb:Q9HC01|uniprotkb:B4DP58|uniprotkb:E7ET30|ensembl:ENSP00000371230 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:kad3_human(display_long)|uniprotkb:AK3(gene name)|psi-mi:AK3(display_short)|uniprotkb:AK3L1(gene name synonym)|uniprotkb:AK6(gene name synonym)|uniprotkb:AKL3L(gene name synonym)|uniprotkb:Adenylate kinase 3(gene name synonym)|uniprotkb:Adenylate kinase 3 alpha-like 1(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088181|imex:IM-21827-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186781.1|refseq:NP_001186782.1|refseq:NP_001186784.1|refseq:NP_001186785.1|refseq:NP_057366.2|ensembl:ENSG00000147853(gene)|ensembl:ENST00000381809(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006172"(ADP biosynthetic process)|go:"GO:0007596"(blood coagulation)|go:"GO:0009142"(nucleoside triphosphate biosynthetic process)|go:"GO:0046033"(AMP metabolic process)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046041"(ITP metabolic process)|go:"GO:0046051"(UTP metabolic process)|go:"GO:0046899"(nucleoside triphosphate adenylate kinase activity)|go:"GO:0046940"(nucleoside monophosphate phosphorylation)|interpro:IPR000850(Adenylate kinase)|interpro:IPR006259(Adenylate kinase, subfamily)|interpro:IPR007862(Adenylate kinase, zinc-finger lid region)|interpro:IPR028586|interpro:IPR033690|interpro:IPR036193|mint:Q9UIJ7|rcsb pdb:1ZD8|rcsb pdb:6ZJB|rcsb pdb:6ZJD|rcsb pdb:6ZJE|reactome:R-HSA-983231|interpro:IPR027417|uniprotkb:Q9UIJ7(identity)|ddbj/embl/genbank:BC013771(identity)|entrezgene/locuslink:50808(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:NDt9xiBjW8L9uXYnyZhVYpVybfA9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:0E210CD3A83D401B|rigid:bh6UIb69Hr4WYG/UpC4lMuhFbs4 false - sufficient binding region:64-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q9NUB4 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9088162|ensembl:ENSP00000369963|ensembl:ENSP00000473907 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:ct141_human(display_long)|uniprotkb:C20orf141(gene name)|psi-mi:C20orf141(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088166|imex:IM-21827-26 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_001243467.1|refseq:NP_542777.1|ensembl:ENSG00000258713(gene)|ensembl:ENST00000380589(transcript)|ensembl:ENST00000603872(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR040425|uniprotkb:Q9NUB4(identity)|ddbj/embl/genbank:BC014591(identity)|entrezgene/locuslink:128653(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:4muKz4pR2cyoWhrjb8hhxeqElgY9606 intact-crc:F9C8C0E14B2E0E4B|rigid:dvHZ5YzOI9suA9bcGmjR2/OPygc false sufficient binding region:64-257("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H714-3 uniprotkb:Q8IUH5 intact:EBI-9088146|ensembl:ENSP00000368061 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:q9h714-3(display_long)|uniprotkb:Protein Rubicon-like(gene name synonym)|uniprotkb:RUBCNL(gene name)|psi-mi:RUBCNL(display_short)|uniprotkb:C13orf18(gene name synonym)|uniprotkb:KIAA0226L(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088143|imex:IM-21827-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2952660(isoform-parent)|ensembl:ENSG00000102445(gene)|ensembl:ENST00000378784(transcript)|uniprotkb:Q9H714-3(isoform-parent)|uniprotkb:Q9H714-3(identity)|ddbj/embl/genbank:BC043488(identity)|entrezgene/locuslink:80183(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) isoform-comment:No experimental confirmation available. - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:QU9iimBaRML+gSDdvaVKaVIEHHI9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:27F09206A54F22ED|rigid:gsFciOOl+baX4r8ONuFw5PQzzFI false - sufficient binding region:64-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BYQ4 uniprotkb:Q8IUH5 intact:EBI-1044640|uniprotkb:Q17RK8|uniprotkb:Q2TB15|ensembl:ENSP00000366950|ensembl:ENSP00000458594|uniprotkb:Q6ISF6 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:kra92_human(display_long)|uniprotkb:Ultrahigh sulfur keratin-associated protein 9.2(gene name synonym)|uniprotkb:Keratin-associated protein 9.2(gene name synonym)|uniprotkb:KRTAP9-2(gene name)|psi-mi:KRTAP9-2(display_short)|uniprotkb:KAP9.2(gene name synonym)|uniprotkb:KRTAP9.2(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088113|imex:IM-21827-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_114167.2|ensembl:ENSG00000239886(gene)|ensembl:ENSG00000263090(gene)|ensembl:ENST00000377721(transcript)|ensembl:ENST00000572513(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0045095"(keratin filament)|interpro:IPR002494(Keratin, high sulphur B2 protein)|reactome:R-HSA-6805567|uniprotkb:Q9BYQ4(identity)|entrezgene/locuslink:83899(identity)|ddbj/embl/genbank:BC110619(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:7/ndNmPl1ZZ8uKrCAznFVagZ1BM9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:2261FFB2BCA59B89|rigid:LSj6/x9I+gyM3IibnIXggoh/oEs false - sufficient binding region:64-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H0F5 uniprotkb:Q8IUH5 intact:EBI-2341200|uniprotkb:Q8N0Y0|uniprotkb:A6PVP9|uniprotkb:B1AM82|uniprotkb:Q7LB33|ensembl:ENSP00000259605|uniprotkb:B1AM81|uniprotkb:B3KSG4|uniprotkb:E7EVL3|uniprotkb:Q9H748 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:rnf38_human(display_long)|uniprotkb:RING finger protein 38(gene name synonym)|uniprotkb:RNF38(gene name)|psi-mi:RNF38(display_short)|uniprotkb:RING-type E3 ubiquitin transferase RNF38(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088128|imex:IM-21827-24 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011516014.1|refseq:XP_011516015.1|refseq:XP_006716784.1|refseq:NP_073618.3|refseq:NP_919309.1|refseq:NP_919310.1|refseq:NP_919311.1|refseq:NP_919313.1|ensembl:ENSG00000137075(gene)|ensembl:ENST00000259605(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008584"(male gonad development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|go:"GO:0036126"(sperm flagellum)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:Q9H0F5|rcsb pdb:1X4J|rcsb pdb:4V3K|rcsb pdb:4V3L|ensembl:ENSP00000259605|ensembl:ENST00000350199|ensembl:ENSP00000343947|ensembl:ENST00000353739|ensembl:ENSP00000335239|ensembl:ENST00000357058|ensembl:ENSP00000349566|ensembl:ENST00000377877|ensembl:ENSP00000367109|ensembl:ENST00000377885|ensembl:ENSP00000367117|ensembl:ENST00000611646|ensembl:ENSP00000483536|refseq:XP_005251423.1|refseq:XP_005251424.1|refseq:XP_005251425.1|refseq:XP_016869784.1|uniprotkb:Q9H0F5(identity)|entrezgene/locuslink:152006(identity)|ddbj/embl/genbank:BC033786(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:leJgsTFAtsRhHPh44pbrpk1wkDo9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:E68006BC1C14B79D|rigid:7L6GOJ5PYj9gilmsvNwq6RwRq6E false - sufficient binding region:64-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A0AVK6 uniprotkb:Q8IUH5 intact:EBI-7779316|ensembl:ENSP00000250024|ensembl:ENSP00000434199|ensembl:ENSP00000481103|uniprotkb:Q8N340|uniprotkb:Q5BKY4|intact:MINT-6541611|uniprotkb:Q9H5M0|uniprotkb:Q3C1U6|uniprotkb:Q2VPJ3|uniprotkb:A8K9H3 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:e2f8_human(display_long)|uniprotkb:E2F8(gene name)|psi-mi:E2F8(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088196|imex:IM-21827-28 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR036388|interpro:IPR036390|mint:A0AVK6|rcsb pdb:4YO2|reactome:R-HSA-6804116|go:"GO:0070365"(hepatocyte differentiation)|ensembl:ENSG00000129173(gene)|ensembl:ENST00000250024(transcript)|ensembl:ENST00000527884(transcript)|ensembl:ENST00000620009(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001890"(placenta development)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0032877"(positive regulation of DNA endoreduplication)|go:"GO:0033301"(cell cycle comprising mitosis without cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060718"(chorionic trophoblast cell differentiation)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|refseq:NP_001243301.1|refseq:NP_001243300.1|refseq:NP_078956.2|uniprotkb:A0AVK6(identity)|ddbj/embl/genbank:BC028244(identity)|entrezgene/locuslink:79733(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) function:Inhibitor of E2F-dependent transcription. Binds DNA independently of DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Appears to regulate a subset of E2F-dependent genes whose products are required for normal cell cycle progession. Modulates the activity of other E2F proteins, such as E2F1, probably by competing or displacing activating E2Fs from promoter binding|comment:mint - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:8RCzz+HuzFPNJ4soR6lxKkq17BU9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:DBE6ED9ECA6E7FED|rigid:BekxLcnMGGSSrXZsZf6Ip5Gfdr4 false sufficient binding region:437-867("MI:0442") sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 intact:EBI-9087227 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 - psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:fkbp6-like_human(display_short)|psi-mi:EBI-9087227(display_long) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088273|imex:IM-21827-32 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) ddbj/embl/genbank:BC022013(identity)|entrezgene/locuslink:8468(identity)|intact:EBI-9087227(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:u6bY9hpLjQ3Lqx5ydjbFZQAvf1g9606 intact-crc:84658A49C9AA476D|rigid:uvPYLO86M+b68zgAVNysbQ+xlzU false sufficient binding region:1-257("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:E9Q3S4 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9088256|ensembl:ENSMUSP00000056254 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:m3k19_mouse(display_long)|uniprotkb:Map3k19(gene name)|psi-mi:Map3k19(display_short)|uniprotkb:SPS1/STE20-related protein kinase YSK4(gene name synonym)|uniprotkb:Ysk4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088258|imex:IM-21827-31 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_035867.1|ensembl:ENSMUSG00000051590(gene)|ensembl:ENSMUST00000061512(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|uniprotkb:E9Q3S4(identity)|entrezgene/locuslink:80122(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:7NGIjWTCdey9QmnJJ5hsxzrQJR410090 intact-crc:BD0F9C5AAB4B07AC|rigid:6PFGMpJA8iRWTMkK6UMtkupZuiQ false sufficient binding region:1-257("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A2RUH7 uniprotkb:Q8IUH5 intact:EBI-9088235|uniprotkb:B7ZME5|uniprotkb:Q5T2Z7|ensembl:ENSP00000349678 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:mbphl_human(display_long)|uniprotkb:MYBPHL(gene name)|psi-mi:MYBPHL(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088240|imex:IM-21827-30 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001010985.2|refseq:NP_001252542.1|refseq:XP_016856662.1|refseq:XP_016856663.1|refseq:XP_016856664.1|ensembl:ENSG00000221986(gene)|ensembl:ENST00000357155(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0030017"(sarcomere)|go:"GO:0036379"(myofilament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|uniprotkb:A2RUH7(identity)|entrezgene/locuslink:343263(identity)|ddbj/embl/genbank:BC132902(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:p/qILEwJE1MLKT/BPKjI2Q8YUqk9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:CEC5591B07B5EC9C|rigid:pqub0wNLTpy8PtH4yX0vPiXd+YA false - sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:A2RU56 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9088215|intact:EBI-12009984|intact:EBI-12820411 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:a2ru56_human(display_long)|uniprotkb:LOC401296(gene name)|psi-mi:LOC401296(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088219|imex:IM-21827-29 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) uniprotkb:A2RU56(identity)|ddbj/embl/genbank:BC132760(identity)|entrezgene/locuslink:401296(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:l/8QJQa5fzS0obFM0gAF9KxDsXY9606 intact-crc:6ED572EC4796817F|rigid:54RdkuO4OVlQHQhCvsLk4KP4Ed8 false sufficient binding region:1-257("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:O94900 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9088321|uniprotkb:Q96AV5|ensembl:ENSP00000354842 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:tox_human(display_long)|uniprotkb:KIAA0808(gene name synonym)|uniprotkb:Thymus high mobility group box protein TOX(gene name synonym)|uniprotkb:TOX(gene name)|psi-mi:TOX(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088326|imex:IM-21827-35 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_055544.1|ensembl:ENSG00000198846(gene)|ensembl:ENST00000361421(transcript)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0002362"(CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment)|go:"GO:0002364"(NK T cell lineage commitment)|go:"GO:0002521"(leukocyte differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032825"(positive regulation of natural killer cell differentiation)|go:"GO:0043373"(CD4-positive, alpha-beta T cell lineage commitment)|go:"GO:0043375"(CD8-positive, alpha-beta T cell lineage commitment)|go:"GO:0048535"(lymph node development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:1901537"(positive regulation of DNA demethylation)|go:"GO:1902232"(regulation of positive thymic T cell selection)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|uniprotkb:O94900(identity)|ddbj/embl/genbank:BC016665(identity)|entrezgene/locuslink:9760(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:DVziSncQVWCpNEfcqQqmRn/mBMk9606 intact-crc:51DD50AA965358C9|rigid:vIlQqqKQeFhywW7WOQyqZq3pPFM false sufficient binding region:1-257("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O00161 uniprotkb:Q8IUH5 intact:EBI-745000|uniprotkb:O00162|uniprotkb:Q13602|uniprotkb:Q6IAE3|ensembl:ENSP00000249647 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:snp23_human(display_long)|uniprotkb:Vesicle-membrane fusion protein SNAP-23(gene name synonym)|uniprotkb:SNAP23(gene name)|psi-mi:SNAP23(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088289|imex:IM-21827-33 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003816.2|refseq:NP_570710.1|ensembl:ENSG00000092531(gene)|ensembl:ENST00000249647(transcript)|go:"GO:0002553"(histamine secretion by mast cell)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006887"(exocytosis)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006903"(vesicle targeting)|go:"GO:0006906"(vesicle fusion)|go:"GO:0015031"(protein transport)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042581"(specific granule)|go:"GO:0042582"(azurophil granule)|go:"GO:0043005"(neuron projection)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0098793"(presynapse)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR000928(SNAP-25)|mint:O00161|rcsb pdb:1NHL|rcsb pdb:3ZUS|reactome:R-HSA-1445148|reactome:R-HSA-199992|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-1236974|uniprotkb:O00161(identity)|ddbj/embl/genbank:BC003686(identity)|entrezgene/locuslink:8773(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:8ZcXbqhusSijGdekDMdkZA5DejY9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:9E143604CBC3F68B|rigid:McBJa6jHMsQGoi4iaYvZ9HHfNCE false - sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O00506 uniprotkb:Q8IUH5 intact:EBI-618295|ensembl:ENSP00000325748|ensembl:ENSP00000384162|ensembl:ENSP00000385687|uniprotkb:Q15522|uniprotkb:Q5BJF1|uniprotkb:A8K7D2|intact:EBI-5773834|uniprotkb:A8K6Z3|uniprotkb:B7Z9K1 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:stk25_human(display_long)|uniprotkb:STK25(gene name)|psi-mi:STK25(display_short)|uniprotkb:SOK1(gene name synonym)|uniprotkb:YSK1(gene name synonym)|uniprotkb:Sterile 20/oxidant stress-response kinase 1(gene name synonym)|uniprotkb:Ste20-like kinase(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088305|imex:IM-21827-34 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115694(gene)|ensembl:ENST00000316586(transcript)|ensembl:ENST00000401869(transcript)|ensembl:ENST00000403346(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051645"(Golgi localization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035060|rcsb pdb:2XIK|rcsb pdb:3W8H|rcsb pdb:4NZW|refseq:NP_006365.2|refseq:NP_001258908.1|refseq:NP_001258909.1|refseq:NP_001269234.1|refseq:NP_001269237.1|refseq:NP_001269236.1|refseq:NP_001258906.1|refseq:NP_001258907.1|dip:DIP-34269N|uniprotkb:O00506(identity)|ddbj/embl/genbank:BC007852(identity)|entrezgene/locuslink:10494(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:yg5mghaePpT2LrC7wdG7xSGe0Pw9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:E8655162CC38F731|rigid:ID+m+QXTZzoij0Cdodnfky9er20 false - sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O95867 uniprotkb:Q8IUH5 intact:EBI-9088345|uniprotkb:Q8IY94|uniprotkb:Q5SRS8|ensembl:ENSP00000364978|ensembl:ENSP00000372905|ensembl:ENSP00000388591|ensembl:ENSP00000409428|ensembl:ENSP00000410398|ensembl:ENSP00000411365|ensembl:ENSP00000415732 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:ly66c_human(display_long)|uniprotkb:C6orf24(gene name synonym)|uniprotkb:G6C(gene name synonym)|uniprotkb:NG24(gene name synonym)|uniprotkb:UNQ1947/PRO4430(orf name)|uniprotkb:LY6G6C(gene name)|psi-mi:LY6G6C(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088342|imex:IM-21827-36 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079537.1|ensembl:ENSG00000204421(gene)|ensembl:ENSG00000206398(gene)|ensembl:ENSG00000228250(gene)|ensembl:ENSG00000228859(gene)|ensembl:ENSG00000235452(gene)|ensembl:ENSG00000235925(gene)|ensembl:ENSG00000236183(gene)|ensembl:ENST00000375819(transcript)|ensembl:ENST00000383413(transcript)|ensembl:ENST00000428121(transcript)|ensembl:ENST00000428498(transcript)|ensembl:ENST00000434915(transcript)|ensembl:ENST00000448386(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR039237|reactome:R-HSA-163125|ensembl:ENST00000419939(transcript)|uniprotkb:O95867(identity)|entrezgene/locuslink:80740(identity)|ddbj/embl/genbank:BC036302(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:daeZFHpHxu5q5w7DPL/wX0HUkBk9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:B689CC4DB408F73A|rigid:+Jv2aUd9oUW2mLHYzwm/rlyGo7s false - sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:P42858 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-466029|uniprotkb:Q9UQB7|ensembl:ENSP00000347184 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:hd_human(display_long)|uniprotkb:HTT(gene name)|psi-mi:HTT(display_short)|uniprotkb:IT15(gene name synonym)|uniprotkb:HD(gene name synonym)|uniprotkb:Huntington disease protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088421|imex:IM-21827-40 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) ensembl:ENSG00000197386(gene)|refseq:NP_002102.4|rcsb pdb:3IOV|rcsb pdb:3IOW|rcsb pdb:3LRH|rcsb pdb:4FE8|rcsb pdb:4FEB|rcsb pdb:4FEC|rcsb pdb:4FED|rcsb pdb:4RAV|rcsb pdb:6EZ8|rcsb pdb:6N8C|rcsb pdb:6RMH|rcsb pdb:6X9O|rcsb pdb:6YEJ|rcsb pdb:7DXJ|rcsb pdb:7DXK|reactome:R-HSA-9022692|ensembl:ENST00000355072(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006915"(apoptotic process)|go:"GO:0007030"(Golgi organization)|go:"GO:0016234"(inclusion body)|go:"GO:0019900"(kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0031648"(protein destabilization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034452"(dynactin binding)|go:"GO:0042297"(vocal learning)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0099111"(microtubule-based transport)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1904504"(positive regulation of lipophagy)|go:"GO:1905289"(regulation of CAMKK-AMPK signaling cascade)|go:"GO:1905337"(positive regulation of aggrephagy)|go:"GO:2000479"(regulation of cAMP-dependent protein kinase activity)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000091(Huntingtin)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|go:"GO:0000132"(establishment of mitotic spindle orientation)|interpro:IPR024613|interpro:IPR028426|mint:P42858|rcsb pdb:2D3X|rcsb pdb:2LD0|rcsb pdb:2LD2|rcsb pdb:3IO4|rcsb pdb:3IO6|rcsb pdb:3IOR|rcsb pdb:3IOT|rcsb pdb:3IOU|dip:DIP-32492N|uniprotkb:P42858(identity)|entrezgene/locuslink:3064(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:KyttHE2o2fORsw6iTh94LB7QShA9606 intact-crc:4E594DC73F2FD6C2|rigid:lIR/BgNT+bjlRLM14OOqZl3D9Uw false sufficient binding region:1-257("MI:0442") sufficient binding region:1-513("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:P09543-2 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9088367|ensembl:ENSP00000377466 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:p09543-2(display_long)|uniprotkb:DNAI(isoform synonym)|uniprotkb:CNP(gene name)|psi-mi:CNP(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088364|imex:IM-21827-37 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) intact:EBI-1059219(isoform-parent)|ensembl:ENSG00000173786(gene)|ensembl:ENST00000393888(transcript)|uniprotkb:P09543-2(isoform-parent)|uniprotkb:P09543-2(identity)|ddbj/embl/genbank:BC011046(identity)|entrezgene/locuslink:1267(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:SjBMCdDayBiWIFuNnb687QFl8MQ9606 intact-crc:1587337A574A02AA|rigid:Ph84VD7m0+4twSfaJSoo+cy8Nh4 false sufficient binding region:1-257("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:P15336 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-1170906|uniprotkb:Q13000|uniprotkb:Q4ZFU9|uniprotkb:Q53RY2|uniprotkb:A1L3Z2|uniprotkb:D3DPE9|uniprotkb:Q8TAR1|uniprotkb:A4D7U4|uniprotkb:G8JLM5|uniprotkb:Q3B7B7|uniprotkb:A4D7U5|uniprotkb:A4D7V1|uniprotkb:Q96JT8|intact:EBI-28988937|ensembl:ENSP00000264110|ensembl:ENSP00000376327 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:atf2_human(display_long)|uniprotkb:ATF2(gene name)|psi-mi:ATF2(display_short)|uniprotkb:CREB2(gene name synonym)|uniprotkb:CREBP1(gene name synonym)|uniprotkb:Activating transcription factor 2(gene name synonym)|uniprotkb:cAMP response element-binding protein CRE-BP1(gene name synonym)|uniprotkb:HB16(gene name synonym)|uniprotkb:Cyclic AMP-responsive element-binding protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088384|imex:IM-21827-38 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_001243019.1|refseq:NP_001243020.1|refseq:NP_001871.2|refseq:NP_001243023.1|ensembl:ENST00000345739|ensembl:ENSP00000340576|ensembl:ENSP00000376327|ensembl:ENST00000409499|ensembl:ENSP00000386282|ensembl:ENST00000409635|ensembl:ENSP00000387093|ensembl:ENST00000409833|ensembl:ENSP00000386526|ensembl:ENST00000426833|ensembl:ENSP00000407911|ensembl:ENSP00000264110|refseq:NP_001243021.1|refseq:NP_001243022.1|ensembl:ENSG00000115966(gene)|ensembl:ENST00000264110(transcript)|ensembl:ENST00000392544(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0009414"(response to water deprivation)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0032915"(positive regulation of transforming growth factor beta2 production)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0110024"(positive regulation of cardiac muscle myoblast proliferation)|go:"GO:1902110"(positive regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1902562"(H4 histone acetyltransferase complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR016378(Transcription factor, cyclic AMP-dependent)|interpro:IPR029836|interpro:IPR036236|mint:P15336|rcsb pdb:1BHI|rcsb pdb:1T2K|rcsb pdb:4H36|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|rcsb pdb:6ZQS|rcsb pdb:6ZR5|reactome:R-HSA-2151201|reactome:R-HSA-3214847|reactome:R-HSA-400253|reactome:R-HSA-450341|reactome:R-HSA-6796648|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9031628|reactome:R-HSA-9633012|reactome:R-HSA-9707616|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043969"(histone H2B acetylation)|go:"GO:0044013"(H2B histone acetyltransferase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060612"(adipose tissue development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097186"(amelogenesis)|dip:DIP-632N|uniprotkb:P15336(identity)|entrezgene/locuslink:1386(identity)|ddbj/embl/genbank:BC026175(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:9krWq+A9Y3xvkInqyJnJs1g9tfc9606 intact-crc:A805862FC433841E|rigid:WMf14R/I1ByvF4hbyKrR7XBPNqQ false sufficient binding region:1-257("MI:0442") sufficient binding region:1-209("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P42858 uniprotkb:Q8IUH5 intact:EBI-466029|uniprotkb:Q9UQB7|ensembl:ENSP00000347184 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:hd_human(display_long)|uniprotkb:HTT(gene name)|psi-mi:HTT(display_short)|uniprotkb:IT15(gene name synonym)|uniprotkb:HD(gene name synonym)|uniprotkb:Huntington disease protein(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088403|imex:IM-21827-39 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000197386(gene)|refseq:NP_002102.4|rcsb pdb:3IOV|rcsb pdb:3IOW|rcsb pdb:3LRH|rcsb pdb:4FE8|rcsb pdb:4FEB|rcsb pdb:4FEC|rcsb pdb:4FED|rcsb pdb:4RAV|rcsb pdb:6EZ8|rcsb pdb:6N8C|rcsb pdb:6RMH|rcsb pdb:6X9O|rcsb pdb:6YEJ|rcsb pdb:7DXJ|rcsb pdb:7DXK|reactome:R-HSA-9022692|ensembl:ENST00000355072(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006915"(apoptotic process)|go:"GO:0007030"(Golgi organization)|go:"GO:0016234"(inclusion body)|go:"GO:0019900"(kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0031648"(protein destabilization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034452"(dynactin binding)|go:"GO:0042297"(vocal learning)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0099111"(microtubule-based transport)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1904504"(positive regulation of lipophagy)|go:"GO:1905289"(regulation of CAMKK-AMPK signaling cascade)|go:"GO:1905337"(positive regulation of aggrephagy)|go:"GO:2000479"(regulation of cAMP-dependent protein kinase activity)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000091(Huntingtin)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|go:"GO:0000132"(establishment of mitotic spindle orientation)|interpro:IPR024613|interpro:IPR028426|mint:P42858|rcsb pdb:2D3X|rcsb pdb:2LD0|rcsb pdb:2LD2|rcsb pdb:3IO4|rcsb pdb:3IO6|rcsb pdb:3IOR|rcsb pdb:3IOT|rcsb pdb:3IOU|dip:DIP-32492N|uniprotkb:P42858(identity)|entrezgene/locuslink:3064(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:KyttHE2o2fORsw6iTh94LB7QShA9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:B650C59C05C7E2C3|rigid:lIR/BgNT+bjlRLM14OOqZl3D9Uw false sufficient binding region:1-506("MI:0442") sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P42858 uniprotkb:Q8IUH5 intact:EBI-466029|uniprotkb:Q9UQB7|ensembl:ENSP00000347184 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:hd_human(display_long)|uniprotkb:HTT(gene name)|psi-mi:HTT(display_short)|uniprotkb:IT15(gene name synonym)|uniprotkb:HD(gene name synonym)|uniprotkb:Huntington disease protein(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088460|imex:IM-21827-42 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000197386(gene)|refseq:NP_002102.4|rcsb pdb:3IOV|rcsb pdb:3IOW|rcsb pdb:3LRH|rcsb pdb:4FE8|rcsb pdb:4FEB|rcsb pdb:4FEC|rcsb pdb:4FED|rcsb pdb:4RAV|rcsb pdb:6EZ8|rcsb pdb:6N8C|rcsb pdb:6RMH|rcsb pdb:6X9O|rcsb pdb:6YEJ|rcsb pdb:7DXJ|rcsb pdb:7DXK|reactome:R-HSA-9022692|ensembl:ENST00000355072(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006915"(apoptotic process)|go:"GO:0007030"(Golgi organization)|go:"GO:0016234"(inclusion body)|go:"GO:0019900"(kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0031648"(protein destabilization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034452"(dynactin binding)|go:"GO:0042297"(vocal learning)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0099111"(microtubule-based transport)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1904504"(positive regulation of lipophagy)|go:"GO:1905289"(regulation of CAMKK-AMPK signaling cascade)|go:"GO:1905337"(positive regulation of aggrephagy)|go:"GO:2000479"(regulation of cAMP-dependent protein kinase activity)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000091(Huntingtin)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|go:"GO:0000132"(establishment of mitotic spindle orientation)|interpro:IPR024613|interpro:IPR028426|mint:P42858|rcsb pdb:2D3X|rcsb pdb:2LD0|rcsb pdb:2LD2|rcsb pdb:3IO4|rcsb pdb:3IO6|rcsb pdb:3IOR|rcsb pdb:3IOT|rcsb pdb:3IOU|dip:DIP-32492N|uniprotkb:P42858(identity)|entrezgene/locuslink:3064(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:KyttHE2o2fORsw6iTh94LB7QShA9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:CD1B2B7FFA0A7580|rigid:lIR/BgNT+bjlRLM14OOqZl3D9Uw false sufficient binding region:1-513("MI:0442")|mutation:18..18-38..38("MI:0118") sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43003 uniprotkb:Q8IUH5 intact:EBI-359038|uniprotkb:B2R5T3|uniprotkb:Q4JCQ8|ensembl:ENSP00000265113|ensembl:ENSP00000371343|ensembl:ENSP00000505057|ensembl:ENSP00000505238|ensembl:ENSP00000506585 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:eaa1_human(display_long)|uniprotkb:SLC1A3(gene name)|psi-mi:SLC1A3(display_short)|uniprotkb:EAAT1(gene name synonym)|uniprotkb:GLAST1(gene name synonym)|uniprotkb:GLAST(gene name synonym)|uniprotkb:Sodium-dependent glutamate/aspartate transporter 1(gene name synonym)|uniprotkb:Solute carrier family 1 member 3(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088481|imex:IM-21827-43 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004163.3|refseq:NP_001160167.1|refseq:XP_005248399.1|refseq:NP_001276869.1|ensembl:ENSG00000079215(gene)|ensembl:ENST00000265113(transcript)|ensembl:ENST00000381918(transcript)|ensembl:ENST00000679983(transcript)|ensembl:ENST00000679992(transcript)|ensembl:ENST00000680318(transcript)|go:"GO:0001504"(neurotransmitter uptake)|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0005314"(high-affinity glutamate transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009449"(gamma-aminobutyric acid biosynthetic process)|go:"GO:0009611"(response to wounding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015501"("glutamate:sodium symporter activity")|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016595"(glutamate binding)|go:"GO:0021545"(cranial nerve development)|go:"GO:0031223"(auditory behavior)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042493"|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046677"(response to antibiotic)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0046872"(metal ion binding)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051938"(L-glutamate import)|go:"GO:0070633"(transepithelial transport)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0070779"(D-aspartate import across plasma membrane)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0098712"(L-glutamate import across plasma membrane)|go:"GO:0098796"(membrane protein complex)|go:"GO:0140009"(L-aspartate import across plasma membrane)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1902476"(chloride transmembrane transport)|interpro:IPR001991("Sodium:dicarboxylate symporter")|interpro:IPR018107|interpro:IPR036458|rcsb pdb:5LLM|rcsb pdb:5LLU|rcsb pdb:5LM4|rcsb pdb:5MJU|reactome:R-HSA-210455|reactome:R-HSA-210500|reactome:R-HSA-425393|reactome:R-HSA-5619062|uniprotkb:P43003(identity)|entrezgene/locuslink:6507(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:z0yfNM2Y4OFgtmwgrVEp8KGJvms9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:5A73F410A7FCAB3C|rigid:XBVwt+HtG5tl/N8KOTsfKNZCEC8 false - sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:P52756 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-714003|uniprotkb:Q93021|uniprotkb:Q9BU14|uniprotkb:Q9UKY8|uniprotkb:Q9UL24|ensembl:ENSP00000343054|uniprotkb:B2RA45|uniprotkb:B4DM16|uniprotkb:B4DMF9|uniprotkb:B4DZ63|uniprotkb:Q9HDA6|intact:EBI-16431417 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:rbm5_human(display_long)|uniprotkb:RNA-binding motif protein 5(gene name synonym)|uniprotkb:Putative tumor suppressor LUCA15(gene name synonym)|uniprotkb:Protein G15(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-9(gene name synonym)|uniprotkb:RBM5(gene name)|psi-mi:RBM5(display_short)|uniprotkb:H37(orf name)|uniprotkb:LUCA15(orf name) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088496|imex:IM-21827-44 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) ensembl:ENSG00000003756(gene)|ensembl:ENST00000347869(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR033094|interpro:IPR034991|interpro:IPR034993|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006396"(RNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000467(D111/G-patch)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036443|interpro:IPR041591|mint:P52756|rcsb pdb:2LK0|rcsb pdb:2LK1|rcsb pdb:2LKZ|rcsb pdb:5MF9|rcsb pdb:5MFY|reactome:R-HSA-72163|refseq:NP_005769.1|refseq:XP_016860992.1|dip:DIP-47277N|uniprotkb:P52756(identity)|entrezgene/locuslink:10181(identity)|ddbj/embl/genbank:BC002957(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:LsPTpaKrGY2xtpYofHbFVXjSi/A9606 intact-crc:3BC38B8D3270F0C0|rigid:jLtsHQuY8xO2ZdCv6YhvY/ihG+8 false sufficient binding region:1-257("MI:0442") sufficient binding region:1-546("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P42858 uniprotkb:Q8IUH5 intact:EBI-466029|uniprotkb:Q9UQB7|ensembl:ENSP00000347184 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:hd_human(display_long)|uniprotkb:HTT(gene name)|psi-mi:HTT(display_short)|uniprotkb:IT15(gene name synonym)|uniprotkb:HD(gene name synonym)|uniprotkb:Huntington disease protein(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088439|imex:IM-21827-41 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000197386(gene)|refseq:NP_002102.4|rcsb pdb:3IOV|rcsb pdb:3IOW|rcsb pdb:3LRH|rcsb pdb:4FE8|rcsb pdb:4FEB|rcsb pdb:4FEC|rcsb pdb:4FED|rcsb pdb:4RAV|rcsb pdb:6EZ8|rcsb pdb:6N8C|rcsb pdb:6RMH|rcsb pdb:6X9O|rcsb pdb:6YEJ|rcsb pdb:7DXJ|rcsb pdb:7DXK|reactome:R-HSA-9022692|ensembl:ENST00000355072(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006915"(apoptotic process)|go:"GO:0007030"(Golgi organization)|go:"GO:0016234"(inclusion body)|go:"GO:0019900"(kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0031648"(protein destabilization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034452"(dynactin binding)|go:"GO:0042297"(vocal learning)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0099111"(microtubule-based transport)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1904504"(positive regulation of lipophagy)|go:"GO:1905289"(regulation of CAMKK-AMPK signaling cascade)|go:"GO:1905337"(positive regulation of aggrephagy)|go:"GO:2000479"(regulation of cAMP-dependent protein kinase activity)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000091(Huntingtin)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|go:"GO:0000132"(establishment of mitotic spindle orientation)|interpro:IPR024613|interpro:IPR028426|mint:P42858|rcsb pdb:2D3X|rcsb pdb:2LD0|rcsb pdb:2LD2|rcsb pdb:3IO4|rcsb pdb:3IO6|rcsb pdb:3IOR|rcsb pdb:3IOT|rcsb pdb:3IOU|dip:DIP-32492N|uniprotkb:P42858(identity)|entrezgene/locuslink:3064(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:KyttHE2o2fORsw6iTh94LB7QShA9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:FB71ECD5B5BCF7F5|rigid:lIR/BgNT+bjlRLM14OOqZl3D9Uw false mutation:18..18-38..38("MI:0118")|sufficient binding region:1-513("MI:0442") sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02086-2 uniprotkb:Q8IUH5 intact:EBI-9088579 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:q02086-2(display_long)|uniprotkb:KIAA0048(gene name synonym)|uniprotkb:SP2(gene name)|psi-mi:SP2(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088583|imex:IM-21827-49 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-8651703(isoform-parent)|uniprotkb:Q02086-2(isoform-parent)|uniprotkb:Q02086-2(identity)|entrezgene/locuslink:6668(identity)|ddbj/embl/genbank:BC033814(identity)|ddbj/embl/genbank:BC016680(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:ys0RZ2dmgXA70qQ5EkoSIuIEYAQ9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:FC136E3945814E62|rigid:NdLxsoBMtF1mWw4vWJEaiT+c/Y8 false - sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:P79483 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-3910269|uniprotkb:Q9TP01|uniprotkb:Q8SP69|uniprotkb:A7MA46|uniprotkb:A0ZXY9|uniprotkb:Q9MYH4|uniprotkb:Q8WLT8|uniprotkb:O46794|uniprotkb:Q860I9|uniprotkb:O78162|uniprotkb:B5AU14|uniprotkb:Q9UIN5|uniprotkb:Q70M87|uniprotkb:Q30144|uniprotkb:Q9UIN3|uniprotkb:O78049|uniprotkb:B5AU13|uniprotkb:Q95IE5|uniprotkb:Q9TQ21|uniprotkb:Q8WLT7|uniprotkb:Q5STE0|uniprotkb:Q6YJU6|uniprotkb:P79663|uniprotkb:B8YAC6|uniprotkb:Q9MYH3|uniprotkb:O46701|uniprotkb:P01913|uniprotkb:Q96H16|uniprotkb:Q2PPD0|uniprotkb:C6H115|uniprotkb:O02875|uniprotkb:B5AU12|uniprotkb:Q9TP02|uniprotkb:Q9BD18|uniprotkb:O19590|uniprotkb:C6H116|uniprotkb:Q507L8|uniprotkb:Q95359|uniprotkb:Q29721|uniprotkb:Q29809|uniprotkb:Q95HM8|uniprotkb:Q9TPB5|uniprotkb:Q7YQ62|uniprotkb:Q9MYA4|uniprotkb:Q9BCP3|uniprotkb:Q5SP44|ensembl:ENSP00000302517|ensembl:ENSP00000372607 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:drb3_human(display_long)|uniprotkb:HLA-DRB3(gene name)|psi-mi:HLA-DRB3(display_short)|uniprotkb:MHC class II antigen DRB3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088547|imex:IM-21827-47 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_072049.2|ensembl:ENSG00000196101(gene)|ensembl:ENSG00000231679(gene)|ensembl:ENST00000307137(transcript)|ensembl:ENST00000383126(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002469"(myeloid dendritic cell antigen processing and presentation)|go:"GO:0002842"(positive regulation of T cell mediated immune response to tumor cell)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032395"(MHC class II receptor activity)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:2000516"(positive regulation of CD4-positive, alpha-beta T cell activation)|interpro:IPR000353(MHC class II, beta chain, N-terminal)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR036179|rcsb pdb:2Q6W|rcsb pdb:3C5J|rcsb pdb:4H1L|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2132295|reactome:R-HSA-389948|reactome:R-HSA-877300|uniprotkb:P79483(identity)|entrezgene/locuslink:3123(identity)|ddbj/embl/genbank:BC008987(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:YTUOVqhKuCtkImhvKfKKRPZfHuU9606 intact-crc:C134F35FE8A98FE4|rigid:vhEpsMa8OeR1q+UHPXNmYRUWAr4 false sufficient binding region:1-257("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:P69892 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-3910089|uniprotkb:A8MZE0|uniprotkb:P02096|uniprotkb:Q14491|uniprotkb:Q68NH9|uniprotkb:Q96FH6|uniprotkb:P62027|uniprotkb:Q96FH7|ensembl:ENSP00000338082 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:hbg2_human(display_long)|uniprotkb:HBG2(gene name)|psi-mi:HBG2(display_short)|uniprotkb:Gamma-2-globin(gene name synonym)|uniprotkb:Hb F Ggamma(gene name synonym)|uniprotkb:Hemoglobin gamma-2 chain(gene name synonym)|uniprotkb:Hemoglobin gamma-G chain(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088531|imex:IM-21827-46 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_000175.1|ensembl:ENSG00000196565(gene)|ensembl:ENST00000336906(transcript)|go:"GO:0005344"(oxygen carrier activity)|go:"GO:0005829"(cytosol)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0031721"(hemoglobin alpha binding)|go:"GO:0031838"(haptoglobin-hemoglobin complex)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043177"(organic acid binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0072562"(blood microparticle)|go:"GO:0098869"(cellular oxidant detoxification)|interpro:IPR000971(Globin, subset)|interpro:IPR009050(Globin-like)|interpro:IPR012292(Globin)|rcsb pdb:1FDH|rcsb pdb:4MQJ|rcsb pdb:4MQK|reactome:R-HSA-983231|interpro:IPR002337(Haemoglobin, beta)|uniprotkb:P69892(identity)|ddbj/embl/genbank:BC010914(identity)|entrezgene/locuslink:3047(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:nhCM/lc1Dqw+ZTSHjiiyHcJIobk9606 intact-crc:CA255540FD390845|rigid:F9Mw/ftBihngPj4S9HPiuQW1woE false sufficient binding region:1-257("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P58304 uniprotkb:Q8IUH5 intact:EBI-6427899|ensembl:ENSP00000261980|uniprotkb:A1A4X6 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:vsx2_human(display_long)|uniprotkb:VSX2(gene name)|psi-mi:VSX2(display_short)|uniprotkb:CHX10(gene name synonym)|uniprotkb:Ceh-10 homeodomain-containing homolog(gene name synonym)|uniprotkb:HOX10(gene name synonym)|uniprotkb:Homeobox protein CHX10(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088515|imex:IM-21827-45 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000119614(gene)|ensembl:ENST00000261980(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007601"(visual perception)|go:"GO:0050896"(response to stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR023339|refseq:NP_878314.1|uniprotkb:P58304(identity)|ddbj/embl/genbank:BC128153(identity)|entrezgene/locuslink:338917(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:qu+5BdJwieBwb2aWty22tshZfmA9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:0D3BA4E38E809589|rigid:sULSaxlkg/CrL4l85gl3PkdGlgU false - sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q01658 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-750300|ensembl:ENSP00000359290|ensembl:ENSP00000359295 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:nc2b_human(display_long)|uniprotkb:Down-regulator of transcription 1(gene name synonym)|uniprotkb:TATA-binding protein-associated phosphoprotein(gene name synonym)|uniprotkb:Negative cofactor 2-beta(gene name synonym)|uniprotkb:DR1(gene name)|psi-mi:DR1(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088563|imex:IM-21827-48 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_001929.1|ensembl:ENSG00000117505(gene)|ensembl:ENST00000370267(transcript)|ensembl:ENST00000370272(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0017054"(negative cofactor 2 complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003958(Transcription factor CBF/NF-Y/archaeal histone)|interpro:IPR009072(Histone-fold)|interpro:IPR042225|mint:Q01658|rcsb pdb:1JFI|reactome:R-HSA-3214847|uniprotkb:Q01658(identity)|entrezgene/locuslink:1810(identity)|ddbj/embl/genbank:BC002809(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:lrcYCVWbIkFU01ETSmd3cX++jLw9606 intact-crc:4606E791D4341B83|rigid:uOlWsd2GkKeq3x03vyMPXC4ju8s false sufficient binding region:1-257("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12893 uniprotkb:Q8IUH5 intact:EBI-8633987|ensembl:ENSP00000266025|uniprotkb:A2IDB7|uniprotkb:Q6IAY4|uniprotkb:Q9UIX3|uniprotkb:O14568|intact:MINT-8162103 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:tm115_human(display_long)|uniprotkb:TMEM115(gene name)|psi-mi:TMEM115(display_short)|uniprotkb:PL6(gene name synonym)|uniprotkb:Placental protein 6(gene name synonym)|uniprotkb:Protein PL6(gene name synonym)|uniprotkb:LUCA11.2(orf name) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088651|imex:IM-21827-53 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000126062(gene)|ensembl:ENST00000266025(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR013861(Protein of unknown function DUF1751, integral membrane, eukaryotic)|interpro:IPR035952|reactome:R-HSA-6807878|refseq:NP_008955.1|uniprotkb:Q12893(identity)|ddbj/embl/genbank:BC011948(identity)|entrezgene/locuslink:11070(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) comment:mint - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:uudMguOuayjmb2C1lyPkBSpSB9Y9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:CD241498EEC8EF6E|rigid:dMkfQuEYcqTlS/LpWlZdfTsBBjw false - sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q06547-2 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-618189|ensembl:ENSP00000370259 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:q06547-2(display_long)|uniprotkb:Beta-2(isoform synonym)|uniprotkb:GABPB1(gene name)|psi-mi:GABPB1(display_short)|uniprotkb:E4TF1B(gene name synonym)|uniprotkb:GABPB(gene name synonym)|uniprotkb:GABPB2(gene name synonym)|uniprotkb:GABP subunit beta-2(gene name synonym)|uniprotkb:Nuclear respiratory factor 2(gene name synonym)|uniprotkb:Transcription factor E4TF1-47(gene name synonym)|uniprotkb:Transcription factor E4TF1-53(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088600|imex:IM-21827-50 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) ensembl:ENSG00000104064(gene)|ensembl:ENST00000380877(transcript)|intact:EBI-618165(gabp2_human)|uniprotkb:Q06547-2(isoform-parent)|uniprotkb:Q06547-2(identity)|ddbj/embl/genbank:BC036080(identity)|entrezgene/locuslink:2553(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:E1QfjsV8iWn4kXDghuOdnMPzmns9606 intact-crc:6A4D2766E83F5B54|rigid:gFJLI1f2mo7Ujka2rpRSG4TN3M8 false sufficient binding region:1-257("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q12824 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-358419|uniprotkb:O75784|uniprotkb:O95474|uniprotkb:Q38GA1|uniprotkb:Q76N08|uniprotkb:Q9UBH2|ensembl:ENSP00000479330|ensembl:ENSP00000494049|uniprotkb:Q17S11 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:snf5_human(display_long)|uniprotkb:SMARCB1(gene name)|psi-mi:SMARCB1(display_short)|uniprotkb:INI1(gene name synonym)|uniprotkb:SNF5L1(gene name synonym)|uniprotkb:Integrase interactor 1 protein(gene name synonym)|uniprotkb:BAF47(gene name synonym)|uniprotkb:SNF5 homolog(gene name synonym)|uniprotkb:BRG1-associated factor 47(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088636|imex:IM-21827-52 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) mint:Q12824|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|rcsb pdb:5AJ1|rcsb pdb:5GJK|rcsb pdb:5L7A|rcsb pdb:5L7B|go:"GO:0007049"(cell cycle)|rcsb pdb:6AX5|go:"GO:0007399"(nervous system development)|rcsb pdb:6KAG|rcsb pdb:6KZ7|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:6UCH|reactome:R-HSA-3214858|go:"GO:0008285"(negative regulation of cell population proliferation)|reactome:R-HSA-8939243|go:"GO:0015074"(DNA integration)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035060"(brahma complex)|go:"GO:0039692"(single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1900110"(negative regulation of histone H3-K9 dimethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|interpro:IPR006939(SNF5/SMARCB1/INI1)|interpro:IPR017393(SWI/SNF chromatin-remodeling complex, component hSNF5/Ini1)|go:"GO:0005730"(nucleolus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|refseq:NP_001007469.1|refseq:NP_003064.2|ensembl:ENSG00000099956(gene)|ensembl:ENSG00000275837(gene)|ensembl:ENST00000618915(transcript)|ensembl:ENST00000644036(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0001741"(XY body)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-27550N|uniprotkb:Q12824(identity)|entrezgene/locuslink:6598(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:GjUm1RYfDvtNuSNGI6iCWpl8L+I9606 intact-crc:8A8B646A4CB22750|rigid:VSAl+97sbwgbKSK/J6RAaXNi3KU false sufficient binding region:1-257("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q13322 uniprotkb:Q8IUH5 intact:EBI-80275|uniprotkb:O00427|uniprotkb:O00701|uniprotkb:O75222|uniprotkb:Q92606|uniprotkb:Q92907|uniprotkb:Q92948|intact:EBI-1760363|ensembl:ENSP00000381793|ensembl:ENSP00000385770|intact:EBI-1965437|uniprotkb:A7VJ95|uniprotkb:A4D258|uniprotkb:A8K0E6|uniprotkb:D3DVM9 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:grb10_human(display_long)|uniprotkb:GRB10(gene name)|psi-mi:GRB10(display_short)|uniprotkb:GRBIR(gene name synonym)|uniprotkb:KIAA0207(gene name synonym)|uniprotkb:GRB10 adapter protein(gene name synonym)|uniprotkb:Insulin receptor-binding protein Grb-IR(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088667|imex:IM-21827-54 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030949"(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045719"(negative regulation of glycogen biosynthetic process)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1904738"(vascular associated smooth muscle cell migration)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015042("BPS (Between PH and SH2)")|interpro:IPR029071|interpro:IPR035036|interpro:IPR035037|interpro:IPR036860|interpro:IPR039664|interpro:IPR039665|mint:Q13322|rcsb pdb:1NRV|rcsb pdb:3HK0|reactome:R-HSA-1433557|reactome:R-HSA-74713|reactome:R-HSA-74749|reactome:R-HSA-74751|reactome:R-HSA-8853659|reactome:R-HSA-9607240|reactome:R-HSA-9648895|ensembl:ENSG00000106070(gene)|ensembl:ENST00000398812(transcript)|ensembl:ENST00000401949(transcript)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010467"(gene expression)|refseq:XP_011513606.1|refseq:XP_011513614.1|refseq:XP_011513618.1|refseq:NP_001001549.1|refseq:NP_001001550.1|refseq:NP_001001555.1|refseq:NP_005302.3|refseq:XP_016867534.1|refseq:XP_016867535.1|refseq:XP_016867552.1|refseq:XP_016867553.1|refseq:XP_016867554.1|refseq:XP_016867555.1|refseq:XP_016867556.1|refseq:XP_016867557.1|dip:DIP-31657N|uniprotkb:Q13322(identity)|ddbj/embl/genbank:BC024285(identity)|entrezgene/locuslink:2887(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:WBLkjS4iCC2gMTzR3izSFXGrBnk9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:A0775F13350BD87B|rigid:n2ioFVEmPuPUv9V2xy7Gn4cSA5M false sufficient binding region:59-594("MI:0442") sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q06547-3 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9088619|ensembl:ENSP00000395771 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:q06547-3(display_long)|uniprotkb:E4TF1B(gene name synonym)|uniprotkb:GABP subunit beta-2(gene name synonym)|uniprotkb:GABPB(gene name synonym)|uniprotkb:GABPB2(gene name synonym)|uniprotkb:Nuclear respiratory factor 2(gene name synonym)|uniprotkb:Transcription factor E4TF1-47(gene name synonym)|uniprotkb:Transcription factor E4TF1-53(gene name synonym)|uniprotkb:GABPB-2(isoform synonym)|uniprotkb:Gamma-1(isoform synonym)|uniprotkb:GABPB1(gene name)|psi-mi:GABPB1(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088616|imex:IM-21827-51 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) ensembl:ENSG00000104064(gene)|ensembl:ENST00000429662(transcript)|intact:EBI-618165(isoform-parent)|uniprotkb:Q06547-3(isoform-parent)|uniprotkb:Q06547-3(identity)|ddbj/embl/genbank:BC016910(identity)|entrezgene/locuslink:2553(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:4gpusaaBb9touca0evEh0Ja+GSY9606 intact-crc:03B5AEC50FAD9C65|rigid:mm764XVGkQW2MEaPt5eOzU6n6eA false sufficient binding region:1-257("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q2TAL8 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-2798044|uniprotkb:Q8TEA5|uniprotkb:Q4G0F7|uniprotkb:Q7L621|ensembl:ENSP00000350094|ensembl:ENSP00000378830|ensembl:ENSP00000412890 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:qric1_human(display_long)|uniprotkb:QRICH1(gene name)|psi-mi:QRICH1(display_short)|uniprotkb:Glutamine-rich protein 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088741|imex:IM-21827-58 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_001307509.1|refseq:NP_001307510.1|refseq:NP_001307511.1|refseq:NP_001307512.1|refseq:NP_001307513.1|refseq:NP_001307514.1|refseq:XP_011532165.1|refseq:NP_060200.2|refseq:NP_942581.1|ensembl:ENSG00000198218(gene)|ensembl:ENST00000357496(transcript)|ensembl:ENST00000395443(transcript)|ensembl:ENST00000424300(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0140467"(integrated stress response signaling)|interpro:IPR021893|uniprotkb:Q2TAL8(identity)|entrezgene/locuslink:54870(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:lZutsiEMc3Fpej5M2vhosiQZnoA9606 intact-crc:918EFEE3A85EEDD7|rigid:ALanV14NpBZypQD9usE8SL22128 false sufficient binding region:1-257("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q15517 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-953708|ensembl:ENSP00000259726|ensembl:ENSP00000388386|ensembl:ENSP00000392863|ensembl:ENSP00000399604|uniprotkb:Q9NRH4|uniprotkb:Q9NRH5|uniprotkb:Q9NRH6|uniprotkb:Q9NRH7|uniprotkb:Q9NRH8|uniprotkb:Q9UBH8|uniprotkb:Q9UIN6|uniprotkb:Q9UIN7|uniprotkb:Q9UIN8|uniprotkb:Q9UIN9|uniprotkb:Q9UIP0|uniprotkb:O43509|uniprotkb:Q5SQ85|uniprotkb:Q5STD2|uniprotkb:Q7LA70|uniprotkb:Q7LA71|uniprotkb:Q86Z04|uniprotkb:Q8IZU4|uniprotkb:Q8IZU5|uniprotkb:Q8IZU6|uniprotkb:Q8N5P3|uniprotkb:Q95IF9|uniprotkb:Q9NP52|uniprotkb:Q9NPE0|uniprotkb:Q9NPG5|uniprotkb:B0S7V2|uniprotkb:B0UYZ7 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:cdsn_human(display_long)|uniprotkb:CDSN(gene name)|psi-mi:CDSN(display_short)|uniprotkb:S protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088706|imex:IM-21827-56 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) ensembl:ENSG00000137197(gene)|ensembl:ENSG00000237114(gene)|ensembl:ENSG00000237123(gene)|ensembl:ENSG00000237165(gene)|ensembl:ENST00000259726(transcript)|ensembl:ENST00000418599(transcript)|ensembl:ENST00000445893(transcript)|ensembl:ENST00000457875(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0003336"(corneocyte desquamation)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008544"(epidermis development)|go:"GO:0030057"(desmosome)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1905716"(negative regulation of cornification)|interpro:IPR026087|mint:Q15517|reactome:R-HSA-6809371|refseq:NP_001255.3|uniprotkb:Q15517(identity)|ddbj/embl/genbank:BC031993(identity)|entrezgene/locuslink:1041(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:2SaKSq9Py2cPLlytyEiH8znQcd49606 intact-crc:05970C7743338776|rigid:c12sh6PXQpk64JDIiwN0gm2o+Ek false sufficient binding region:1-257("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14847-2 uniprotkb:Q8IUH5 intact:EBI-9088686 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:q14847-2(display_long)|uniprotkb:MLN50(gene name synonym)|uniprotkb:Metastatic lymph node gene 50 protein(gene name synonym)|uniprotkb:LASP1(gene name)|psi-mi:LASP1(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088690|imex:IM-21827-55 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-742828(isoform-parent)|uniprotkb:Q14847-2(isoform-parent)|uniprotkb:Q14847-2(identity)|ddbj/embl/genbank:BC007560(identity)|entrezgene/locuslink:3927(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) isoform-comment:No experimental confirmation available. - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:uxyDFrkrlmWPmKK1RLEHRbysWj09606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:C394AA239CFDA445|rigid:n8d6vF31PncI6iKrjt6vnxM8mQo false - sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q155Q3-2 uniprotkb:Q8IUH5 intact:EBI-9088722|ensembl:ENSP00000480808 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:q155q3-2(display_long)|uniprotkb:CCD1(gene name synonym)|uniprotkb:Coiled-coil protein DIX1(gene name synonym)|uniprotkb:DIX domain-containing protein 1(gene name synonym)|uniprotkb:KIAA1735(gene name synonym)|uniprotkb:s-DIXDC1(isoform synonym)|uniprotkb:DIXDC1(gene name)|psi-mi:DIXDC1(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088726|imex:IM-21827-57 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1104700(isoform-parent)|ensembl:ENSG00000150764(gene)|ensembl:ENST00000615255(transcript)|uniprotkb:Q155Q3-2(identity)|entrezgene/locuslink:85458(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) isoform-comment:Major isoform. Preferentially expressed in cardiac and skeletal muscles. Initiator Met-1 is removed. Contains a N-myristoyl glycine at position 2. - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:ABLpXbDQcnGM7cwKKz4X9yfLweI9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:60AFBE9D9EC1F64E|rigid:wLuJaXiFOz43qwSABu3l2UfQFfQ false - sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q5T447 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-2691157|uniprotkb:B3KPV7|uniprotkb:B3KRH4|uniprotkb:Q5T448|uniprotkb:Q9H783|ensembl:ENSP00000361245 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:hecd3_human(display_long)|uniprotkb:HECT domain-containing protein 3(gene name synonym)|uniprotkb:HECTD3(gene name)|psi-mi:HECTD3(display_short)|uniprotkb:HECT-type E3 ubiquitin transferase HECTD3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088791|imex:IM-21827-61 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_078878.3|ensembl:ENSG00000126107(gene)|ensembl:ENST00000372172(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR000569(HECT)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR035983|interpro:IPR042469|mint:Q5T447|reactome:R-HSA-983168|go:"GO:0019905"(syntaxin binding)|uniprotkb:Q5T447(identity)|entrezgene/locuslink:79654(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:laodrF8CReKmM4d6n3sHGBmQB6Q9606 intact-crc:9464C845CDCAEB0B|rigid:9KKdd8iXFP5NM4XM8rVBbQkVtG8 false sufficient binding region:1-257("MI:0442") sufficient binding region:652-861("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5JXC2 uniprotkb:Q8IUH5 intact:EBI-2801965|uniprotkb:C0KL22|uniprotkb:Q9H839|uniprotkb:Q96HU6|uniprotkb:Q9HA00|ensembl:ENSP00000235332 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:miip_human(display_long)|uniprotkb:IIP45(gene name synonym)|uniprotkb:IGFBP2-binding protein(gene name synonym)|uniprotkb:Invasion-inhibitory protein 45(gene name synonym)|uniprotkb:MIIP(gene name)|psi-mi:MIIP(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088775|imex:IM-21827-60 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011540197.1|refseq:XP_011540198.1|refseq:NP_068752.2|ensembl:ENSG00000116691(gene)|ensembl:ENST00000235332(transcript)|go:"GO:0030336"(negative regulation of cell migration)|interpro:IPR031466|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|uniprotkb:Q5JXC2(identity)|entrezgene/locuslink:60672(identity)|ddbj/embl/genbank:BC008068(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:mcdo7ZVPdEWQymXdVLJSLHzvqoU9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:D5F47C977B351376|rigid:1KbhIQsMSYGg8+M/6BLWdCJhXTM false - sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q49AJ0 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-720896|uniprotkb:Q2WGJ7|uniprotkb:Q3KP46|uniprotkb:O95879|uniprotkb:B5MDB3|ensembl:ENSP00000378710 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:f135b_human(display_long)|uniprotkb:C8orfK32(gene name synonym)|uniprotkb:FAM135B(gene name)|psi-mi:FAM135B(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088756|imex:IM-21827-59 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_056996.2|refseq:XP_011515366.1|refseq:XP_011515370.1|ensembl:ENSG00000147724(gene)|ensembl:ENST00000395297(transcript)|go:"GO:0044255"(cellular lipid metabolic process)|interpro:IPR007751(Protein of unknown function DUF676, hydrolase-like)|interpro:IPR022122|interpro:IPR029058|interpro:IPR044294|refseq:XP_016868959.1|uniprotkb:Q49AJ0(identity)|ddbj/embl/genbank:BC106912(identity)|entrezgene/locuslink:51059(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:XE0d4ZZGHLzfUGafphGsL6YcTdw9606 intact-crc:CE8B32EF3AA2DF58|rigid:DqxyOYujqqHfZccFTA1N4VcrYxo false sufficient binding region:1-257("MI:0442") sufficient binding region:801-1212("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5VYS8-5 uniprotkb:Q8IUH5 intact:EBI-9088812 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:q5vys8-5(display_long)|uniprotkb:TUT7(gene name)|psi-mi:TUT7(display_short)|uniprotkb:HS2(gene name synonym)|uniprotkb:KIAA1711(gene name synonym)|uniprotkb:ZCCHC6(gene name synonym)|uniprotkb:Zinc finger CCHC domain-containing protein 6(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088809|imex:IM-21827-62 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2810086(isoform-parent)|uniprotkb:Q5VYS8-5(isoform-parent)|uniprotkb:Q5VYS8-5(identity)|entrezgene/locuslink:79670(identity)|ddbj/embl/genbank:BC032456(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) isoform-comment:No experimental confirmation available. - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:y+wD4uDI5MYjBvKag8sm1MNAE689606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:8872F088873EBB0E|rigid:OGkiCX3SWbb7Buugm74tuuCqnqo false - sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q6GQQ9 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-527784|uniprotkb:Q8WWA7|uniprotkb:Q9NQ53|uniprotkb:Q9UFF4|uniprotkb:Q5SZ60|ensembl:ENSP00000462729|uniprotkb:D3DUZ8|uniprotkb:B7Z643 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:otu7b_human(display_long)|uniprotkb:Zinc finger protein Cezanne(gene name synonym)|uniprotkb:Zinc finger A20 domain-containing protein 1(gene name synonym)|uniprotkb:Cellular zinc finger anti-NF-kappa-B protein(gene name synonym)|uniprotkb:OTUD7B(gene name)|psi-mi:OTUD7B(display_short)|uniprotkb:ZA20D1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088850|imex:IM-21827-64 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) dip:DIP-33805N|ensembl:ENSG00000264522(gene)|ensembl:ENST00000581312(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002385"(mucosal immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0035871"(protein K11-linked deubiquitination)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071947"(protein deubiquitination involved in ubiquitin-dependent protein catabolic process)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR002653(Zinc finger, A20-type)|interpro:IPR003323(Ovarian tumour, otubain)|rcsb pdb:5LRU|rcsb pdb:5LRV|rcsb pdb:5LRW|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5689896|ensembl:ENSP00000462729|refseq:NP_064590.2|uniprotkb:Q6GQQ9(identity)|entrezgene/locuslink:56957(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:JZKj6CpuUOQ3aqvmg3YC9OnivGM9606 intact-crc:62A436DFEBB4CF0C|rigid:iN09sYHWpQeFGS2Isf0JRNaWKVY false sufficient binding region:1-257("MI:0442") sufficient binding region:1-427("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q6I9S2 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-711215 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:q6i9s2_human(display_long)|uniprotkb:SNW1(gene name)|psi-mi:SNW1(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088868|imex:IM-21827-65 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) interpro:IPR017862|interpro:IPR004015(SKIP/SNW)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|uniprotkb:Q6I9S2(identity)|entrezgene/locuslink:22938(identity)|ddbj/embl/genbank:CR457433(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:wFXsOKrt6F0ZWvKl0aTKRrIzKTg9606 intact-crc:A172663043134CD7|rigid:icwNyCsSYCRrNqGS3BBjSQfNM2I false sufficient binding region:1-257("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96JL9 uniprotkb:Q8IUH5 intact:EBI-8489497|ensembl:ENSP00000292530|intact:MINT-8417739|uniprotkb:Q8TDL0|intact:EBI-9088887|uniprotkb:Q6P2E6|uniprotkb:Q86WS6 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:zn333_human(display_long)|uniprotkb:ZNF333(gene name)|psi-mi:ZNF333(display_short)|uniprotkb:KIAA1806(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088884|imex:IM-21827-66 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000160961(gene)|ensembl:ENST00000292530(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|mint:Q96JL9|reactome:R-HSA-212436|refseq:NP_001287841.1|refseq:XP_011526664.1|refseq:NP_115809.1|refseq:XP_016882856.1|uniprotkb:Q6P2E6(identity)|ddbj/embl/genbank:BC064571(identity)|entrezgene/locuslink:84449(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) comment:mint|comment:homomint - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:JIZiWPk26qS+PUNyJxgHWnUrOWA9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:C891293FA8707404|rigid:r7jyKeqmnArHybkLCDWoJn/MoCI false - sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6ZMI0-4 uniprotkb:Q8IUH5 intact:EBI-9088904 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:q6zmi0-4(display_long)|uniprotkb:CCDC128(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 128(gene name synonym)|uniprotkb:KLRAQ motif-containing protein 1(gene name synonym)|uniprotkb:KLRAQ1(gene name synonym)|uniprotkb:PPP1R21(gene name)|psi-mi:PPP1R21(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088908|imex:IM-21827-67 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-5235703(isoform-parent)|uniprotkb:Q6ZMI0-4(identity)|ddbj/embl/genbank:BC040721(identity)|entrezgene/locuslink:129285(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) isoform-comment:No experimental confirmation available. - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:vDwjg+g7BMCazIS+sHWjnOJ5+V89606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:F2E56E83D25D960E|rigid:NkW6vPiMh3iZfnVf9zFJILnR1rE false - sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6DKI2 uniprotkb:Q8IUH5 intact:EBI-9088829|uniprotkb:B0AZM7|ensembl:ENSP00000329932|ensembl:ENSP00000491587 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:leg9c_human(display_long)|uniprotkb:Galectin-9-like protein B(gene name synonym)|uniprotkb:LGALS9C(gene name)|psi-mi:LGALS9C(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088834|imex:IM-21827-63 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035167.2|ensembl:ENSG00000171916(gene)|ensembl:ENSG00000284021(gene)|ensembl:ENST00000328114(transcript)|ensembl:ENST00000639265(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016936"(galactoside binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:2000562"(negative regulation of CD4-positive, alpha-beta T cell proliferation)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|uniprotkb:Q6DKI2(identity)|entrezgene/locuslink:654346(identity)|ddbj/embl/genbank:BC073889(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:XWu3uFBJCOzMmzpaBdn4LOTAKrY9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:6291B385A004EBA3|rigid:MMBdf9x61SPr+0L+eGsG36CJqAI false - sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7Z739 uniprotkb:Q8IUH5 intact:EBI-2849837|uniprotkb:Q659A3|uniprotkb:B3KXL4|uniprotkb:Q63Z37|ensembl:ENSP00000473496 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:ythd3_human(display_long)|uniprotkb:YTHDF3(gene name)|psi-mi:YTHDF3(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088971|imex:IM-21827-71 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_689971.4|refseq:NP_001264742.1|refseq:NP_001264743.1|refseq:NP_001264744.1|refseq:NP_001264745.1|refseq:NP_001264746.1|refseq:NP_001264747.1|ensembl:ENSG00000185728(gene)|ensembl:ENST00000539294(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043022"(ribosome binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0070925"(organelle assembly)|go:"GO:1901163"(regulation of trophoblast cell migration)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|interpro:IPR007275(YT521-B-like protein)|mint:Q7Z739|rcsb pdb:6ZOT|uniprotkb:Q7Z739(identity)|ddbj/embl/genbank:BC052970(identity)|entrezgene/locuslink:253943(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:M1/1RMOQiQ7kD+J9KMmEq9RZebw9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:4173FED1E29728FE|rigid:Istz4abNYTaKqmGlMY9kQGZmRe8 false - sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6ZN57 uniprotkb:Q8IUH5 intact:EBI-7236323|uniprotkb:A5PLN5|uniprotkb:B7ZM23|intact:MINT-1199669|uniprotkb:Q9H6Z6|ensembl:ENSP00000354453|ensembl:ENSP00000430531|ensembl:ENSP00000430980 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:zfp2_human(display_long)|uniprotkb:ZFP2(gene name)|psi-mi:ZFP2(display_short)|uniprotkb:ZNF751(gene name synonym)|uniprotkb:Zinc finger protein 751(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088924|imex:IM-21827-68 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_085116.2|ensembl:ENSG00000198939(gene)|ensembl:ENST00000361362(transcript)|ensembl:ENST00000520301(transcript)|ensembl:ENST00000523286(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|reactome:R-HSA-212436|uniprotkb:Q6ZN57(identity)|ddbj/embl/genbank:BC132779(identity)|entrezgene/locuslink:80108(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) comment:mint|comment:homomint|function:Probable transcription factor involved in neuronal differentiation and/or phenotypic maintenance - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:IpvoJkjjdMAy1IBCicP3URazNpg9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:D7A5D105906291DE|rigid:vJ43LN615rEHRhCN5bVEyiEPLhk false - sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7Z698 uniprotkb:Q8IUH5 intact:EBI-7082156|ensembl:ENSP00000348753|uniprotkb:A1L3V4|uniprotkb:B7Z5K7|intact:MINT-8020116|uniprotkb:Q2NKX6|uniprotkb:E9PEP0|uniprotkb:D6W5F7 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:spre2_human(display_long)|uniprotkb:SPRED2(gene name)|psi-mi:SPRED2(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088940|imex:IM-21827-69 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000198369(gene)|ensembl:ENST00000356388(transcript)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0005173"(stem cell factor receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:1902747"(negative regulation of lens fiber cell differentiation)|interpro:IPR000697(EVH1)|interpro:IPR007875(Sprouty)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023337|interpro:IPR041937|rcsb pdb:2JP2|reactome:R-HSA-5658442|reactome:R-HSA-5658623|reactome:R-HSA-6802953|refseq:NP_861449.2|refseq:NP_001121682.1|uniprotkb:Q7Z698(identity)|ddbj/embl/genbank:BC130292(identity)|entrezgene/locuslink:200734(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) comment:mint - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:Ao93NebBS40A8fFJk5b2ttbat0I9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:9B6C31B959D80D5D|rigid:40vtx39wrol3pP7yYIACxFQTNM4 false - sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7Z699 uniprotkb:Q8IUH5 intact:EBI-5235340|uniprotkb:B2RPJ8|uniprotkb:Q05D53|uniprotkb:Q8N256|ensembl:ENSP00000299084 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:spre1_human(display_long)|uniprotkb:SPRED1(gene name)|psi-mi:SPRED1(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088956|imex:IM-21827-70 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_689807.1|ensembl:ENSG00000166068(gene)|ensembl:ENST00000299084(transcript)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0005173"(stem cell factor receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0060979"(vasculogenesis involved in coronary vascular morphogenesis)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:1902747"(negative regulation of lens fiber cell differentiation)|interpro:IPR000697(EVH1)|interpro:IPR007875(Sprouty)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023337|interpro:IPR041937|mint:Q7Z699|rcsb pdb:3SYX|rcsb pdb:6V65|rcsb pdb:6V6F|reactome:R-HSA-5658442|reactome:R-HSA-5658623|reactome:R-HSA-6802953|uniprotkb:Q7Z699(identity)|entrezgene/locuslink:161742(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:+jGnxx5TP0aeldLkqVGfO8uY2ko9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:0A49366643DB3522|rigid:0Gd7Ug3r/IvK1t7u7qhESghx+5E false - sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q7Z7F0-4 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9089060 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:q7z7f0-4(display_long)|uniprotkb:KHDC4(gene name)|psi-mi:KHDC4(display_short)|uniprotkb:BLOM7(gene name synonym)|uniprotkb:Brings lots of money 7(gene name synonym)|uniprotkb:KIAA0907(gene name synonym)|uniprotkb:Pre-mRNA splicing factor protein KHDC4(gene name synonym)|uniprotkb:SNORA80EHG(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089064|imex:IM-21827-76 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) intact:EBI-751942(isoform-parent)|uniprotkb:Q7Z7F0-4(isoform-parent)|uniprotkb:Q7Z7F0-4(identity)|ddbj/embl/genbank:BC027182(identity)|entrezgene/locuslink:22889(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:JF3OuduN/zsFLFuUGUE9eqTJHto9606 intact-crc:3B12D43DEAA3600A|rigid:tQrGTqCrtLuJNjTDl6n3D3P5qSM false sufficient binding region:1-257("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q7Z7C8-2 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9089028|ensembl:ENSP00000411900 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:q7z7c8-2(display_long)|uniprotkb:Protein taube nuss(gene name synonym)|uniprotkb:TAFII43(gene name synonym)|uniprotkb:TBN(gene name synonym)|uniprotkb:TBP-associated factor 43 kDa(gene name synonym)|uniprotkb:TBP-associated factor 8(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 43 kDa subunit(gene name synonym)|uniprotkb:TAF8(gene name)|psi-mi:TAF8(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089025|imex:IM-21827-74 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) intact:EBI-1560220(isoform-parent)|uniprotkb:Q7Z7C8-2(isoform-parent)|ensembl:ENSG00000137413(gene)|ensembl:ENST00000456846(transcript)|uniprotkb:Q7Z7C8-2(identity)|ddbj/embl/genbank:BC119678(identity)|entrezgene/locuslink:129685(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:OgcTKj/KZcl6+08jAwVUdZ4Etzs9606 intact-crc:2239948BCB21375A|rigid:DcRCCJcrcGfPQ+/31XhaKBEZFag false sufficient binding region:1-257("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q7Z7C8 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-1560220|uniprotkb:Q8N4R9|uniprotkb:Q96M52|uniprotkb:Q5T0K1|ensembl:ENSP00000362068 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:taf8_human(display_long)|uniprotkb:TBN(gene name synonym)|uniprotkb:TBP-associated factor 8(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 43 kDa subunit(gene name synonym)|uniprotkb:TBP-associated factor 43 kDa(gene name synonym)|uniprotkb:Protein taube nuss(gene name synonym)|uniprotkb:TAF8(gene name)|psi-mi:TAF8(display_short)|uniprotkb:TAFII43(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089006|imex:IM-21827-73 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_612639.2|refseq:XP_011512598.1|dip:DIP-60591N|ensembl:ENSG00000137413(gene)|ensembl:ENST00000372977(transcript)|go:"GO:0001112"(DNA-templated transcription open complex formation)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0045598"(regulation of fat cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051457"(maintenance of protein location in nucleus)|interpro:IPR006565(Bromodomain transcription factor)|interpro:IPR009072(Histone-fold)|interpro:IPR019473|interpro:IPR037818|rcsb pdb:4WV4|rcsb pdb:4WV6|rcsb pdb:5FUR|rcsb pdb:6MZC|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGG|rcsb pdb:7EGH|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|reactome:R-HSA-6807505|rcsb pdb:7EGE|uniprotkb:Q7Z7C8(identity)|ddbj/embl/genbank:BC033728(identity)|entrezgene/locuslink:129685(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:WMGuVWGlsQ60hS5qzNqGojl7rAo9606 intact-crc:3761390AED31CCD4|rigid:Ss64uZ70P6xadSAu+lnJKl2zJZ4 false sufficient binding region:1-257("MI:0442") sufficient binding region:1-163("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7Z783 uniprotkb:Q8IUH5 intact:EBI-9088990|intact:EBI-12862946 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:q7z783_human(display_long) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9088987|imex:IM-21827-72 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007875(Sprouty)|interpro:IPR030780|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0005737"(cytoplasm)|go:"GO:0032587"(ruffle membrane)|go:"GO:0042127"(regulation of cell population proliferation)|uniprotkb:Q7Z783(identity)|entrezgene/locuslink:10253(identity)|ddbj/embl/genbank:BC004205(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:e2aAamwhAPGI99/OO3G9dqo3u4w9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:016D13B7730CAB39|rigid:f2OX5qb07HPqwqPVyX1gZOWEdo4 false - sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7Z7F0 uniprotkb:Q8IUH5 intact:EBI-751942|uniprotkb:O94981|uniprotkb:Q7L7Q2|uniprotkb:Q7Z7E9|uniprotkb:Q8TBQ0|ensembl:ENSP00000357304 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:khdc4_human(display_long)|uniprotkb:KHDC4(gene name)|psi-mi:KHDC4(display_short)|uniprotkb:BLOM7(gene name synonym)|uniprotkb:Brings lots of money 7(gene name synonym)|uniprotkb:KIAA0907(gene name synonym)|uniprotkb:Pre-mRNA splicing factor protein KHDC4(gene name synonym)|uniprotkb:SNORA80EHG(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089045|imex:IM-21827-75 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055764.2|ensembl:ENSG00000132680(gene)|ensembl:ENST00000368321(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006376"(mRNA splice site selection)|interpro:IPR031121|interpro:IPR036612|mint:Q7Z7F0|rcsb pdb:2YQR|uniprotkb:Q7Z7F0(identity)|entrezgene/locuslink:22889(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:JjYHRjwyj+jqt/m4RFA7bwsWEOY9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:7CA7D4AC924BA25F|rigid:41L++AWCDixxBsW2FebomaGAsyE false - sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q8IUH5 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089104|imex:IM-21827-78 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|ddbj/embl/genbank:BC050324(identity)|entrezgene/locuslink:23390(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:9EC4515BC92D9C7A|rigid:3F96lWb4skN4/qdb2khWY9O/paQ false sufficient binding region:1-257("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q8IUH5 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089120|imex:IM-21827-79 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|entrezgene/locuslink:23390(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:1E3AD5161F43551F|rigid:3F96lWb4skN4/qdb2khWY9O/paQ false sufficient binding region:1-257("MI:0442") sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q8IUH5 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089138|imex:IM-21827-80 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|entrezgene/locuslink:23390(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:9924E566416F1B0B|rigid:3F96lWb4skN4/qdb2khWY9O/paQ false sufficient binding region:1-257("MI:0442") sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q86U86-2 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9089083|ensembl:ENSP00000386593 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:q86u86-2(display_long)|uniprotkb:BAF180(gene name synonym)|uniprotkb:BRG1-associated factor 180(gene name synonym)|uniprotkb:PB1(gene name synonym)|uniprotkb:Polybromo-1D(gene name synonym)|uniprotkb:PBRM1(gene name)|psi-mi:PBRM1(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089080|imex:IM-21827-77 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) intact:EBI-637807(isoform-parent)|ensembl:ENSG00000163939(gene)|ensembl:ENST00000409057(transcript)|uniprotkb:Q86U86-2(isoform-parent)|uniprotkb:Q86U86-2(identity)|entrezgene/locuslink:55193(identity)|ddbj/embl/genbank:BC015323(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:BswL7oYxf4hhVxnGZHeZZf9oUP89606 intact-crc:C360D37C0331752D|rigid:Q54FRRSKX8bOi/mJe64wO4a3O8g false sufficient binding region:1-257("MI:0442") sufficient binding region:1329-1634("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IZS5 uniprotkb:Q8IUH5 intact:EBI-8477661|intact:MINT-8417707|uniprotkb:Q8IZS3|uniprotkb:Q8IZR9|uniprotkb:Q7Z2X5|uniprotkb:Q8IUL6|uniprotkb:Q8IZS1|uniprotkb:Q8IUM1 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:ofcc1_human(display_long)|uniprotkb:OFCC1(gene name)|psi-mi:OFCC1(display_short)|uniprotkb:MRDS1(gene name synonym)|uniprotkb:Orofacial clefting chromosomal breakpoint region candidate 1 protein(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089210|imex:IM-21827-84 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR031390|mint:Q8IZS5|go:"GO:0048471"(perinuclear region of cytoplasm)|uniprotkb:Q8IZS5(identity)|entrezgene/locuslink:266553(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) comment:mint|comment:homomint - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:4cDMDdOlk+3FSJ96g5F+dQ5dIJw9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:98876D804102698F|rigid:tc/mEYEhNikQsFm5JD2kHESOLQI false - sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IZ08 uniprotkb:Q8IUH5 intact:EBI-716029|uniprotkb:Q7Z604|uniprotkb:Q86SM3|uniprotkb:Q8NH39|ensembl:ENSP00000378548|ensembl:ENSP00000432696 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:gp135_human(display_long)|uniprotkb:GPR135(gene name)|psi-mi:GPR135(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089195|imex:IM-21827-83 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_072093.2|ensembl:ENSG00000181619(gene)|ensembl:ENST00000395116(transcript)|ensembl:ENST00000481661(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:1990763"(arrestin family protein binding)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|refseq:XP_016877085.1|refseq:XP_016877086.1|refseq:XP_016877087.1|refseq:XP_016877088.1|uniprotkb:Q8IZ08(identity)|entrezgene/locuslink:64582(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:LXYH6yJ2px0ecRFCcSbFQ8cm0Ho9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:D05780874B2E78E2|rigid:6jV3/xsuWoqpNOY3cP6Y6+4xMR0 false - sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IX90 uniprotkb:Q8IUH5 intact:EBI-1773976|uniprotkb:Q96D22|uniprotkb:Q5VZV5|uniprotkb:Q86WR2|uniprotkb:Q8NBG1|uniprotkb:A2A330|uniprotkb:A2A331|uniprotkb:B2RBY2|ensembl:ENSP00000319417 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:ska3_human(display_long)|uniprotkb:SKA3(gene name)|psi-mi:SKA3(display_short)|uniprotkb:C13orf3(gene name synonym)|uniprotkb:RAMA1(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089176|imex:IM-21827-82 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001159489.1|refseq:NP_659498.4|refseq:XP_005266345.1|ensembl:ENSG00000165480(gene)|ensembl:ENST00000314759(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|interpro:IPR033341|mint:Q8IX90|rcsb pdb:4AJ5|uniprotkb:Q8IX90(identity)|ddbj/embl/genbank:BC013418(identity)|entrezgene/locuslink:221150(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:F3lm7ntNHVutZ+X66pTMEfyyJ+E9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:201CE6C8993B43E7|rigid:9tzozp8qygJnroHMzvJym8Ky0pA false sufficient binding region:43-412("MI:0442") sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q8IUR5-4 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9089156 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:q8iur5-4(display_long)|uniprotkb:TMTC1(gene name)|psi-mi:TMTC1(display_short)|uniprotkb:Transmembrane and TPR repeat-containing protein 1(gene name synonym)|uniprotkb:ARG99(orf name) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089160|imex:IM-21827-81 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) intact:EBI-7958193(isoform-parent)|uniprotkb:Q8IUR5-4(isoform-parent)|uniprotkb:Q8IUR5-4(identity)|ddbj/embl/genbank:BC028716(identity)|entrezgene/locuslink:83857(identity) psi-mi:"MI:0469"(intact) - isoform-comment:No experimental confirmation available. figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:MPFUDnqOF7onImbRnTv4jhnqAhk9606 intact-crc:E436B8C1251499AA|rigid:KCjCQgXICOIeNyk9pmOUnle3oEE false sufficient binding region:1-257("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8N9I9 uniprotkb:Q8IUH5 intact:EBI-2340258|uniprotkb:Q8NDS8|uniprotkb:Q8NAU6|uniprotkb:Q53ZZ2|ensembl:ENSP00000338050|ensembl:ENSP00000447873|ensembl:ENSP00000449294 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:dtx3_human(display_long)|uniprotkb:DTX3(gene name)|psi-mi:DTX3(display_short)|uniprotkb:RNF154(gene name synonym)|uniprotkb:RING finger protein 154(gene name synonym)|uniprotkb:Protein deltex-3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DTX3(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089241|imex:IM-21827-86 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001273174.1|refseq:NP_001273175.1|refseq:XP_011536324.1|refseq:NP_848597.1|refseq:XP_005268754.1|refseq:XP_005268755.1|refseq:XP_005268757.1|refseq:XP_005268760.1|ensembl:ENSG00000178498(gene)|ensembl:ENST00000337737(transcript)|ensembl:ENST00000548198(transcript)|ensembl:ENST00000548804(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039396|interpro:IPR039398|interpro:IPR039399|uniprotkb:Q8N9I9(identity)|entrezgene/locuslink:196403(identity)|ddbj/embl/genbank:BC114498(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:Ma7JBhgMdFofCeWESbf8h1iLAHY9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:0BFAF0FB3D138AFE|rigid:SmoPAG3G/IMuh3GwmMds/0S4U9I false - sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q8NBJ7 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-723091|uniprotkb:Q14DW5|uniprotkb:Q53ZE3|uniprotkb:Q96BH2|uniprotkb:Q9BRN3|uniprotkb:Q9BWI1|uniprotkb:Q9Y405|ensembl:ENSP00000400922|uniprotkb:B4DU41|uniprotkb:B4DWQ0 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:sumf2_human(display_long)|uniprotkb:SUMF2(gene name)|psi-mi:SUMF2(display_short)|uniprotkb:Sulfatase-modifying factor 2(gene name synonym)|uniprotkb:PSEC0171(orf name)|uniprotkb:UNQ1968/PRO4500(orf name)|uniprotkb:Paralog of formylglycine-generating enzyme(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089257|imex:IM-21827-87 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_001035934.2|refseq:NP_001035935.2|refseq:NP_001139805.1|refseq:NP_056226.2|refseq:NP_001123541.1|ensembl:ENSG00000129103(gene)|ensembl:ENST00000434526(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR005532(Sulphate-modifying factor-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR042095|rcsb pdb:1Y4J|reactome:R-HSA-1660662|reactome:R-HSA-1663150|uniprotkb:Q8NBJ7(identity)|ddbj/embl/genbank:BC111092(identity)|entrezgene/locuslink:25870(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:l5K3nL4Cf/sygAOzoS2fcH4rmL09606 intact-crc:07BF1433BEF2B87B|rigid:omvHFD64/3V/vv62lkEEf04cAQ4 false sufficient binding region:1-257("MI:0442") sufficient binding region:1-301("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q8NI37 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9089276|uniprotkb:Q68DZ7|uniprotkb:B3KWC5|uniprotkb:Q6UY82|ensembl:ENSP00000346255 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:pptc7_human(display_long)|uniprotkb:T-cell activation protein phosphatase 2C(gene name synonym)|uniprotkb:T-cell activation protein phosphatase 2C-like(gene name synonym)|uniprotkb:TAPP2C(gene name synonym)|uniprotkb:PPTC7(gene name)|psi-mi:PPTC7(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089283|imex:IM-21827-88 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_644812.1|ensembl:ENSG00000196850(gene)|ensembl:ENST00000354300(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0010795"(regulation of ubiquinone biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR036457|interpro:IPR039123|uniprotkb:Q8NI37(identity)|ddbj/embl/genbank:BC111551(identity)|entrezgene/locuslink:160760(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:A4ZUHRgvKA6nWms93t6Zz2mbQyY9606 intact-crc:B36825C99B978727|rigid:Tcz2x536nbzfPa4bSlYTj9FC9Ms false sufficient binding region:1-257("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IZU1 uniprotkb:Q8IUH5 intact:EBI-8468186|intact:MINT-8417663|uniprotkb:B7ZLH5|uniprotkb:Q2M2D1|ensembl:ENSP00000370391|ensembl:ENSP00000440163 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:fam9a_human(display_long)|uniprotkb:FAM9A(gene name)|psi-mi:FAM9A(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089225|imex:IM-21827-85 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_777611.1|refseq:NP_001164657.1|ensembl:ENSG00000183304(gene)|ensembl:ENST00000381003(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0007286"(spermatid development)|go:"GO:0051321"(meiotic cell cycle)|mint:Q8IZU1|ensembl:ENST00000543214(transcript)|uniprotkb:Q8IZU1(identity)|entrezgene/locuslink:171482(identity)|ddbj/embl/genbank:BC113449(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) comment:mint|comment:homomint - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:2LlKKs3tvntm/ZPF5v5U1g3QIEg9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:89164A4FBAB75BB8|rigid:xVnjazZYM0qTIjHLfYF4/eFlqlQ false - sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q8NI51 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9089302|uniprotkb:A6XGL8|uniprotkb:A6XGN3|uniprotkb:A6XGM3|uniprotkb:A6XGM2|uniprotkb:E7EQ27|uniprotkb:Q5JUG4|uniprotkb:Q9BZ30|uniprotkb:A1L4C6|uniprotkb:E9PBA9|uniprotkb:E7EUE3|uniprotkb:A6XGN1|uniprotkb:A0S6W1|uniprotkb:A6XGM8|uniprotkb:Q9NQJ3|uniprotkb:A6XGN0|uniprotkb:A6XGN2|uniprotkb:A6XGN4|ensembl:ENSP00000243914|ensembl:ENSP00000360239|ensembl:ENSP00000476398|ensembl:ENSP00000476783 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:ctcfl_human(display_long)|uniprotkb:BORIS(gene name synonym)|uniprotkb:Brother of the regulator of imprinted sites(gene name synonym)|uniprotkb:CCCTC-binding factor(gene name synonym)|uniprotkb:CTCF paralog(gene name synonym)|uniprotkb:CTCF-like protein(gene name synonym)|uniprotkb:Cancer/testis antigen 27(gene name synonym)|uniprotkb:Zinc finger protein CTCF-T(gene name synonym)|uniprotkb:CTCFL(gene name)|psi-mi:CTCFL(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089299|imex:IM-21827-89 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_001255979.1|refseq:NP_001255969.1|refseq:NP_001255970.1|refseq:NP_001255971.1|refseq:NP_001255972.1|refseq:NP_001255973.1|refseq:NP_001255974.1|refseq:NP_001255975.1|refseq:NP_001255976.1|refseq:NP_001255977.1|refseq:NP_001255978.1|refseq:NP_001255983.1|refseq:NP_542185.2|refseq:NP_001255980.1|refseq:NP_001255981.1|refseq:NP_001255984.1|ensembl:ENSG00000124092(gene)|ensembl:ENST00000243914(transcript)|ensembl:ENST00000371196(transcript)|ensembl:ENST00000608263(transcript)|ensembl:ENST00000609232(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016571"(histone methylation)|go:"GO:0016604"(nuclear body)|go:"GO:0042393"(histone binding)|go:"GO:0043035"(chromatin insulator sequence binding)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|uniprotkb:Q8NI51(identity)|entrezgene/locuslink:140690(identity)|ddbj/embl/genbank:BC130486(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:Zd3flpao63rSVBYKkR13uDujwwA9606 intact-crc:3B7D16AA292084D3|rigid:cSD/gTV5MSHgbYeuF2h4RMriPk0 false sufficient binding region:1-257("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8TAK5 uniprotkb:Q8IUH5 intact:EBI-8468945|intact:MINT-6778891|uniprotkb:D3DV14|uniprotkb:B1AVJ8|uniprotkb:Q8NAR5|ensembl:ENSP00000357914 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:gabp2_human(display_long)|uniprotkb:GABPB2(gene name)|psi-mi:GABPB2(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089334|imex:IM-21827-90 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001310837.1|refseq:NP_653219.1|refseq:XP_016855738.1|ensembl:ENSG00000143458(gene)|ensembl:ENST00000368918(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q8TAK5|uniprotkb:Q8TAK5(identity)|entrezgene/locuslink:126626(identity)|ddbj/embl/genbank:BC027033(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) function:"May function as transcription factor capable of interacting with purine rich repeats (GA repeats)"|comment:mint|comment:homomint - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:F1UTCglE16qDpbAHMtdpL/zq8XY9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:09E27C3FAE0D18CB|rigid:0DPgK/8EniO42b3NGUbi8DRveBk false - sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8TB46 uniprotkb:Q8IUH5 intact:EBI-9089350 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:q8tb46_human(display_long)|uniprotkb:ANKRD50(gene name)|psi-mi:ANKRD50(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089354|imex:IM-21827-91 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002110(Ankyrin)|interpro:IPR020683|refseq:NP_001161354.1|interpro:IPR036770|uniprotkb:Q8TB46(identity)|ddbj/embl/genbank:BC024725(identity)|entrezgene/locuslink:57182(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:gOx3gwV0m7oQOyIM1E2v9yxrdIE9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:2FBAD012556B9274|rigid:4zXbSPBrKxIpTaaByRahXfziyzw false - sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8TBZ3-3 uniprotkb:Q8IUH5 intact:EBI-9089370|ensembl:ENSP00000314209 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:q8tbz3-3(display_long)|uniprotkb:Protein DMR(gene name synonym)|uniprotkb:WDR20(gene name)|psi-mi:WDR20(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089374|imex:IM-21827-92 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000140153(gene)|ensembl:ENST00000322340(transcript)|intact:EBI-2511486(isoform-parent)|uniprotkb:Q8TBZ3-3(isoform-parent)|uniprotkb:Q8TBZ3-3(identity)|ddbj/embl/genbank:BC030654(identity)|entrezgene/locuslink:91833(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) isoform-comment:No experimental confirmation available. - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:otidfsXltyFEysVSLi3UrJXa8Ik9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:EA39E95498C30EDA|rigid:Qs9I9NlyCJgNZ54KFJIPBpW/XcY false - sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q96B77 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9089409|uniprotkb:B2RAY0|uniprotkb:Q9Y4T4|ensembl:ENSP00000331640 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:tm186_human(display_long)|uniprotkb:C16orf51(gene name synonym)|uniprotkb:TMEM186(gene name)|psi-mi:TMEM186(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089415|imex:IM-21827-94 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_056236.2|ensembl:ENSG00000184857(gene)|ensembl:ENST00000333050(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR026571|reactome:R-HSA-611105|reactome:R-HSA-6799198|uniprotkb:Q96B77(identity)|ddbj/embl/genbank:BC015912(identity)|entrezgene/locuslink:25880(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:x+vajajo/J0W0DVGKWU12wFid3c9606 intact-crc:D38FA3B59609940F|rigid:DhF51sS98Xnm21kZ2f4ocul0+3I false sufficient binding region:1-257("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q96BJ3 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-4401674|uniprotkb:A8K1F0|uniprotkb:Q49A81|uniprotkb:Q5JRA4|uniprotkb:Q658P1|uniprotkb:Q9H9E8|ensembl:ENSP00000339161 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:aida_human(display_long)|uniprotkb:AIDA(gene name)|psi-mi:AIDA(display_short)|uniprotkb:C1orf80(gene name synonym)|uniprotkb:Axin interaction partner and dorsalization antagonist(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089431|imex:IM-21827-95 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_073742.2|ensembl:ENSG00000186063(gene)|ensembl:ENST00000340020(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0016020"(membrane)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048264"(determination of ventral identity)|interpro:IPR023421|interpro:IPR025939|interpro:IPR035892|interpro:IPR036818|uniprotkb:Q96BJ3(identity)|ddbj/embl/genbank:BC015535(identity)|entrezgene/locuslink:64853(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:Eo7oyV29ug5MrDH2coUbbW68pdc9606 intact-crc:FA0968EBA5DE63CF|rigid:neyY8E9mAmNEgCv625ZWb2FpyDw false sufficient binding region:1-257("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96D30 uniprotkb:Q8IUH5 intact:EBI-9089447 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:q96d30_human(display_long)|uniprotkb:ADD1(gene name)|psi-mi:ADD1(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089451|imex:IM-21827-96 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001303(Class II aldolase/adducin, N-terminal)|interpro:IPR027766|interpro:IPR036409|go:"GO:0005856"(cytoskeleton)|uniprotkb:Q96D30(identity)|entrezgene/locuslink:118(identity)|ddbj/embl/genbank:BC013393(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:WnCqvsp5mYOSQrmTOM3+wSkwNyo9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:8A7359EA250C8961|rigid:QyfX9u5RkwmOpDgfjdAO2rt1eus false - sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q93079 uniprotkb:Q8IUH5 intact:EBI-352469|uniprotkb:Q4VB74|uniprotkb:B2R541|ensembl:ENSP00000479169 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:h2b1h_human(display_long)|uniprotkb:H2BC9(gene name)|psi-mi:H2BC9(display_short)|uniprotkb:H2B-clustered histone 9(gene name synonym)|uniprotkb:H2BFJ(gene name synonym)|uniprotkb:HIST1H2BH(gene name synonym)|uniprotkb:Histone H2B.j(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089390|imex:IM-21827-93 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003515.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019899"(enzyme binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|ensembl:ENSG00000275713(gene)|ensembl:ENST00000619466(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0097677"(STAT family protein binding)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|uniprotkb:Q93079(identity)|ddbj/embl/genbank:BC096116(identity)|entrezgene/locuslink:8345(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:W+7KkrtV9xv7ELLxmJFnI4LQoME9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:B67A69B8DA409484|rigid:bVxrxb5DvPeRBrbyG8QfAwNYPDY false sufficient binding region:1-126("MI:0442") sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q96FT7-4 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9089489 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:q96ft7-4(display_long)|uniprotkb:ACCN4(gene name synonym)|uniprotkb:Amiloride-sensitive cation channel 4(gene name synonym)|uniprotkb:Amiloride-sensitive cation channel 4, pituitary(gene name synonym)|uniprotkb:ASIC4(gene name)|psi-mi:ASIC4(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089493|imex:IM-21827-98 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) intact:EBI-9116154(isoform-parent)|uniprotkb:Q96FT7-4(isoform-parent)|uniprotkb:Q96FT7-4(identity)|entrezgene/locuslink:55515(identity)|ddbj/embl/genbank:BC073912(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:CSLvNLnImrUBCvFC147zKf5LPBM9606 intact-crc:F321BADD75858FAF|rigid:mMHAVmgdz+NPe9xt3YENtnOq/ns false sufficient binding region:1-257("MI:0442") sufficient binding region:347-594("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96HB5 uniprotkb:Q8IUH5 intact:EBI-744556|uniprotkb:B4DTU2|ensembl:ENSP00000470294|ensembl:ENSP00000474761|ensembl:ENSP00000475676|uniprotkb:A8K5Q5|uniprotkb:B4DF24|uniprotkb:F5GZU4|uniprotkb:B4DFC1 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:cc120_human(display_long)|uniprotkb:CCDC120(gene name)|psi-mi:CCDC120(display_short)|uniprotkb:JM11(orf name) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089512|imex:IM-21827-99 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001156795.1|refseq:NP_296375.1|go:"GO:0005814"(centriole)|go:"GO:0008104"(protein localization)|go:"GO:0030426"(growth cone)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0120103"(centriolar subdistal appendage)|interpro:IPR021774|interpro:IPR039108|interpro:IPR043447|ensembl:ENSG00000147144(gene)|ensembl:ENST00000496529(transcript)|ensembl:ENST00000597275(transcript)|ensembl:ENST00000606812(transcript)|go:"GO:0005768"(endosome)|refseq:NP_001258764.1|refseq:NP_001258765.1|refseq:NP_001156793.2|refseq:NP_001156794.1|uniprotkb:Q96HB5(identity)|ddbj/embl/genbank:BC008769(identity)|entrezgene/locuslink:90060(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:uBgmQJDTqECaTKOU/uQQHkWB/Nc9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:8EE367419DD9DE2F|rigid:cSHvl+60mlPE+ysugK3zH2Vqfzw false - sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96J42 uniprotkb:Q8IUH5 intact:EBI-2908241|uniprotkb:Q96MT2|uniprotkb:Q9H639|intact:EBI-28986412|uniprotkb:D3DQA9|ensembl:ENSP00000351157 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:txd15_human(display_long)|uniprotkb:TXNDC15(gene name)|psi-mi:TXNDC15(display_short)|uniprotkb:C5orf14(gene name synonym)|uniprotkb:UNQ335/PRO534(orf name) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089528|imex:IM-21827-100 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078991.3|ensembl:ENSP00000351157|ensembl:ENSG00000113621(gene)|ensembl:ENST00000358387(transcript)|go:"GO:0005929"(cilium)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR042418|uniprotkb:Q96J42(identity)|entrezgene/locuslink:79770(identity)|ddbj/embl/genbank:BC001615(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:JA9hAed4dW9h2pqQEzmiO15bOtA9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:73AD15E8DC5A91C1|rigid:b3D53WFKk/OST6RSFNFXCI3DKNQ false - sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96DA2 uniprotkb:Q8IUH5 intact:EBI-9089467|uniprotkb:Q5JT79|uniprotkb:Q8NEX3|ensembl:ENSP00000358466 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:rb39b_human(display_long)|uniprotkb:RAB39B(gene name)|psi-mi:RAB39B(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089473|imex:IM-21827-97 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_741995.1|ensembl:ENSG00000155961(gene)|mint:Q96DA2|rcsb pdb:6S5F|reactome:R-HSA-8873719|reactome:R-HSA-8876198|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0043005"(neuron projection)|go:"GO:0050808"(synapse organization)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041818|ensembl:ENST00000369454(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031489"(myosin V binding)|go:"GO:0031982"(vesicle)|uniprotkb:Q96DA2(identity)|entrezgene/locuslink:116442(identity)|ddbj/embl/genbank:BC009714(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:2lE8eIl2KSFMUz/cOKCRZmHO9oA9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:D7C914204F220B9D|rigid:07ZaWyzFNsIcfH4+i3nqvPipu2g false - sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q99504 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9089567|uniprotkb:Q99813|uniprotkb:O95463|uniprotkb:A8K190|uniprotkb:B4DIR7|uniprotkb:B4DNZ7|uniprotkb:Q8IVX7|ensembl:ENSP00000362978 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:eya3_human(display_long)|uniprotkb:EYA3(gene name)|psi-mi:EYA3(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089564|imex:IM-21827-102 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_001981.2|ensembl:ENST00000373863|ensembl:ENSP00000362970|ensembl:ENSP00000362978|ensembl:ENST00000436342|ensembl:ENSP00000405587|ensembl:ENST00000540618|ensembl:ENSP00000442558|refseq:NP_001269489.1|refseq:NP_001269490.1|refseq:NP_001269491.1|dip:DIP-60448N|ensembl:ENSG00000158161(gene)|ensembl:ENST00000373871(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007601"(visual perception)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016576"(histone dephosphorylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0046872"(metal ion binding)|go:"GO:0048856"(anatomical structure development)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR006545(EYA)|interpro:IPR028472|interpro:IPR028479|interpro:IPR038102|interpro:IPR042577|reactome:R-HSA-5693565|uniprotkb:Q99504(identity)|entrezgene/locuslink:2140(identity)|ddbj/embl/genbank:BC029500(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:FrzkCC1XK5NDTbrxH25HEKcj5P89606 intact-crc:A2F16FFDB8841375|rigid:ck6fYtyVCfI6RgnN80U4aCn1bQg false sufficient binding region:1-257("MI:0442") sufficient binding region:1-361("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96Q83-2 uniprotkb:Q8IUH5 intact:EBI-9089544|ensembl:ENSP00000436788 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:q96q83-2(display_long)|uniprotkb:ABH3(gene name synonym)|uniprotkb:Alkylated DNA repair protein alkB homolog 3(gene name synonym)|uniprotkb:DEPC-1(gene name synonym)|uniprotkb:DEPC1(gene name synonym)|uniprotkb:Prostate cancer antigen 1(gene name synonym)|uniprotkb:ALKBH3(gene name)|psi-mi:ALKBH3(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089548|imex:IM-21827-101 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6658697(isoform-parent)|ensembl:ENSG00000166199(gene)|ensembl:ENST00000530803(transcript)|uniprotkb:Q96Q83-2(isoform-parent)|uniprotkb:Q96Q83-2(identity)|entrezgene/locuslink:221120(identity)|ddbj/embl/genbank:BC067257(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) isoform-comment:No experimental confirmation available. - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:8R0LiTtXZp0Q0b/2mCOBDQrSln09606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:F0AD7C9B4C7189AC|rigid:poUONzCJt9/KfTDH1to/Rs31AuU false - sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BYG3 uniprotkb:Q8IUH5 intact:EBI-2561019|ensembl:ENSP00000285814|uniprotkb:Q8TB66|uniprotkb:A8K788|uniprotkb:Q96ED4 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:mk67i_human(display_long)|uniprotkb:NIFK(gene name)|psi-mi:NIFK(display_short)|uniprotkb:MKI67IP(gene name synonym)|uniprotkb:NOPP34(gene name synonym)|uniprotkb:Nucleolar phosphoprotein Nopp34(gene name synonym)|uniprotkb:Nucleolar protein interacting with the FHA domain of pKI-67(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089606|imex:IM-21827-104 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009303"(rRNA transcription)|go:"GO:0016072"(rRNA metabolic process)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021043|interpro:IPR035979|mint:Q9BYG3|rcsb pdb:2AFF|ensembl:ENSG00000155438(gene)|ensembl:ENST00000285814(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000794"(condensed nuclear chromosome)|refseq:NP_115766.3|dip:DIP-28134N|uniprotkb:Q9BYG3(identity)|entrezgene/locuslink:84365(identity)|ddbj/embl/genbank:BC024238(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:DUc8AnzFxJjbK+cTW5H83GQcf6o9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:C37225AA543EB735|rigid:9Cc/bMHiPYAotp733cjq9HcoTwc false - sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q9BWG6 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-748391|uniprotkb:Q5JR74|uniprotkb:B4DWR1|ensembl:ENSP00000357901 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:scnm1_human(display_long)|uniprotkb:SCNM1(gene name)|psi-mi:SCNM1(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089590|imex:IM-21827-103 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_001191777.1|refseq:NP_001191785.1|refseq:NP_076946.1|ensembl:ENSG00000163156(gene)|ensembl:ENST00000368905(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR031622|interpro:IPR031625|interpro:IPR033570|rcsb pdb:7DVQ|uniprotkb:Q9BWG6(identity)|ddbj/embl/genbank:BC000264(identity)|entrezgene/locuslink:79005(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:qHAQZoyALsU6q35kdDr6i8Puo7M9606 intact-crc:0DA7103F0CB51116|rigid:7Fu8htHxjlj//0f+xqmPQiPARFU false sufficient binding region:1-257("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q9BYN7 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9089622|uniprotkb:Q5JXM8|uniprotkb:B7ZM09|uniprotkb:B2RXE5|uniprotkb:Q96ST5|uniprotkb:A2RUF4|ensembl:ENSP00000364346 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:zn341_human(display_long)|uniprotkb:ZNF341(gene name)|psi-mi:ZNF341(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089631|imex:IM-21827-105 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_001269862.1|refseq:NP_001269864.1|refseq:NP_116208.3|ensembl:ENSG00000131061(gene)|ensembl:ENST00000375200(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|uniprotkb:Q9BYN7(identity)|entrezgene/locuslink:84905(identity)|ddbj/embl/genbank:BC132873(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:dEc17LamYWGrumF7ngc3Ayq4Q5E9606 intact-crc:1D17160C9F71637E|rigid:KpU+DBjQL9o4VU+iGkyxZWvqrSY false sufficient binding region:1-257("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H0C2 uniprotkb:Q8IUH5 intact:EBI-6149672|ensembl:ENSP00000281154 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:adt4_human(display_long)|uniprotkb:SLC25A31(gene name)|psi-mi:SLC25A31(display_short)|uniprotkb:AAC4(gene name synonym)|uniprotkb:ADP,ATP carrier protein 4(gene name synonym)|uniprotkb:ANT4(gene name synonym)|uniprotkb:Adenine nucleotide translocator 4(gene name synonym)|uniprotkb:SFEC(gene name synonym)|uniprotkb:Solute carrier family 25 member 31(gene name synonym)|uniprotkb:Sperm flagellar energy carrier protein(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089663|imex:IM-21827-107 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001305396.1|refseq:NP_112581.1|ensembl:ENSG00000151475(gene)|ensembl:ENST00000281154(transcript)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0031514"(motile cilium)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|uniprotkb:Q9H0C2(identity)|entrezgene/locuslink:83447(identity)|ddbj/embl/genbank:BC022032(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:41l4B5IjJBVvzEcuNsV2T931oWs9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:0040B4C9674D60C8|rigid:r84xicAPo8JTnigp8X3BwfumwFE false - sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q9C004 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-354861|uniprotkb:Q6QIX2|uniprotkb:A4FVB3|uniprotkb:Q9C003|uniprotkb:A4FVB2|ensembl:ENSP00000399468 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:spy4_human(display_long)|uniprotkb:SPRY4(gene name)|psi-mi:SPRY4(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089647|imex:IM-21827-106 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_001120968.1|refseq:NP_112226.2|refseq:NP_001280218.1|refseq:NP_001280219.1|refseq:XP_011535987.1|refseq:XP_016865399.1|ensembl:ENSG00000187678(gene)|ensembl:ENST00000434127(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0032587"(ruffle membrane)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048513"(animal organ development)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR007875(Sprouty)|interpro:IPR030790|mint:Q9C004|rcsb pdb:3BUN|uniprotkb:Q9C004(identity)|ddbj/embl/genbank:BC125095(identity)|entrezgene/locuslink:81848(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:NjkIqofg1Fl1PXj8FXVFz10JOUg9606 intact-crc:CA98F544A38DA62E|rigid:h++nln/HV6t7YeW22DNyvvtlQH4 false sufficient binding region:1-257("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q9HD47-3 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9089733|ensembl:ENSP00000413190 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:q9hd47-3(display_long)|uniprotkb:MOG1(gene name synonym)|uniprotkb:RANGNRF(gene name synonym)|uniprotkb:Ran-binding protein MOG1(gene name synonym)|uniprotkb:HSPC165(orf name)|uniprotkb:HSPC236(orf name)|uniprotkb:MDS5(orf name)|uniprotkb:RANGRF(gene name)|psi-mi:RANGRF(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089737|imex:IM-21827-111 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) intact:EBI-9116212(isoform-parent)|uniprotkb:Q9HD47-3(isoform-parent)|ensembl:ENSG00000108961(gene)|ensembl:ENST00000439238(transcript)|uniprotkb:Q9HD47-3(identity)|ddbj/embl/genbank:BC012552(identity)|entrezgene/locuslink:29098(identity)|ddbj/embl/genbank:BC006486(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:0+3MFqLXECsq7nWicVeBZPHoG8k9606 intact-crc:F0CFADD2F055CAD5|rigid:yTeajVoXrf5SVJdsrtl6CMHs1E8 false sufficient binding region:1-257("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9HD42 uniprotkb:Q8IUH5 intact:EBI-1057156|uniprotkb:Q14468|uniprotkb:Q15779|uniprotkb:Q96G31|uniprotkb:A2RU09|ensembl:ENSP00000380998 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:chm1a_human(display_long)|uniprotkb:CHMP1A(gene name)|psi-mi:CHMP1A(display_short)|uniprotkb:CHMP1(gene name synonym)|uniprotkb:PCOLN3(gene name synonym)|uniprotkb:KIAA0047(gene name synonym)|uniprotkb:PRSM1(gene name synonym)|uniprotkb:Chromatin-modifying protein 1a(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 46-1(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089718|imex:IM-21827-110 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002759.2|go:"GO:0036258"(multivesicular body assembly)|ensembl:ENSG00000131165(gene)|ensembl:ENST00000397901(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005769"(early endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0012505"(endomembrane system)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0051301"(cell division)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1904903"(ESCRT III complex disassembly)|interpro:IPR005024(Snf7)|interpro:IPR029888|mint:Q9HD42|rcsb pdb:2JQ9|rcsb pdb:2YMB|rcsb pdb:4A5X|reactome:R-HSA-9610379|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|dip:DIP-50647N|uniprotkb:Q9HD42(identity)|entrezgene/locuslink:5119(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:w7fMwItYOqS/JXLy+8DWcJBaEPE9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:F35334C48CBF606E|rigid:XMIlL7tqu+XhcljJekB66ohRaUs false - sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H6U6-6 uniprotkb:Q8IUH5 intact:EBI-9089698|ensembl:ENSP00000464825 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:q9h6u6-6(display_long)|uniprotkb:Breast carcinoma-amplified sequence 3(gene name synonym)|uniprotkb:GAOB1(gene name synonym)|uniprotkb:Maaab2(isoform synonym)|uniprotkb:BCAS3(gene name)|psi-mi:BCAS3(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089695|imex:IM-21827-109 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6083685(isoform-parent)|ensembl:ENSG00000141376(gene)|ensembl:ENST00000588874(transcript)|uniprotkb:Q9H6U6-6(identity)|ddbj/embl/genbank:BC001250(identity)|entrezgene/locuslink:54828(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:Me4sRk7FArlInTLgRmhTOzW9SG49606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:8DC6C142F03A295A|rigid:vd79z8dwUwKVVbF64puBbglP85k false sufficient binding region:295-684("MI:0442") sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H172 uniprotkb:Q8IUH5 intact:EBI-8584118|ensembl:ENSP00000479253|ensembl:ENSP00000481728|ensembl:ENSP00000484289|uniprotkb:A8K1B5|intact:MINT-2840344|uniprotkb:Q8WWH0|uniprotkb:Q8WWH1|uniprotkb:Q8WWH2 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:abcg4_human(display_long)|uniprotkb:ABCG4(gene name)|psi-mi:ABCG4(display_short)|uniprotkb:WHITE2(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089679|imex:IM-21827-108 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q9H172|reactome:R-HSA-1369062|interpro:IPR043926|ensembl:ENST00000615496(transcript)|ensembl:ENST00000619701(transcript)|ensembl:ENST00000622721(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0034041"(ABC-type sterol transporter activity)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR017871|interpro:IPR027417|ensembl:ENSG00000172350(gene)|refseq:XP_011541254.1|refseq:NP_071452.2|refseq:NP_001135977.1|refseq:NP_001335120.1|refseq:NP_001335121.1|uniprotkb:Q9H172(identity)|entrezgene/locuslink:64137(identity)|ddbj/embl/genbank:BC041091(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) comment:mint|function:May be involved in macrophage lipid homeostasis - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:HSCN2Fw45BkkxySzxnvQJXQdtJM9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:8233FCA1157C2169|rigid:QjrJnaqiZ/76UlyIFhSn4E3pWgk false - sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NP64 uniprotkb:Q8IUH5 intact:EBI-746345|uniprotkb:Q6PKH4|uniprotkb:Q9NYG4|uniprotkb:Q9P0M8|uniprotkb:D3DPN4|ensembl:ENSP00000343557|ensembl:ENSP00000362819|uniprotkb:B4DY38 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:no40_human(display_long)|uniprotkb:Zinc finger CCHC domain-containing protein 17(gene name synonym)|uniprotkb:Putative S1 RNA-binding domain protein(gene name synonym)|uniprotkb:Pnn-interacting nucleolar protein(gene name synonym)|uniprotkb:ZCCHC17(gene name)|psi-mi:ZCCHC17(display_short)|uniprotkb:HSPC243(orf name)|uniprotkb:HSPC251(orf name)|uniprotkb:LDC4(orf name)|uniprotkb:PS1D(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089754|imex:IM-21827-112 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001269495.1|refseq:NP_001269496.1|refseq:NP_001269497.1|refseq:NP_001269498.1|refseq:NP_001269499.1|refseq:NP_001269500.1|refseq:NP_001269501.1|refseq:NP_001269502.1|refseq:NP_001269503.1|refseq:XP_006710744.1|refseq:NP_057589.2|refseq:XP_011539869.1|ensembl:ENSG00000121766(gene)|ensembl:ENST00000344147(transcript)|ensembl:ENST00000373714(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0042802"(identical protein binding)|go:"GO:0043489"(RNA stabilization)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR003029(S1, RNA binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR037320|mint:Q9NP64|rcsb pdb:2CQO|uniprotkb:Q9NP64(identity)|entrezgene/locuslink:51538(identity)|ddbj/embl/genbank:BC007446(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:e71wAulRWX6cM59s3g8R42PWXeU9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:B59F8FE8E9C7D2D0|rigid:XL5j8SOdx39WMx17mcIOaszwbfU false - sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q9NSI2 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-5457304|ensembl:ENSP00000291634 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:slx9_human(display_long)|uniprotkb:SLX9(gene name)|psi-mi:SLX9(display_short)|uniprotkb:C21orf70(gene name synonym)|uniprotkb:FAM207A(gene name synonym)|uniprotkb:PRED56(orf name) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089786|imex:IM-21827-114 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_001303912.1|refseq:NP_001303913.1|refseq:NP_001303914.1|refseq:NP_001303915.1|refseq:NP_001303917.1|refseq:NP_478070.1|ensembl:ENSG00000160256(gene)|ensembl:ENST00000291634(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005730"(nucleolus)|go:"GO:0030686"(90S preribosome)|go:"GO:0030688"(preribosome, small subunit precursor)|interpro:IPR028160|uniprotkb:Q9NSI2(identity)|ddbj/embl/genbank:BC009341(identity)|entrezgene/locuslink:85395(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:pCNahk8BsVfGLtrB/Y290fJCA5g9606 intact-crc:990FCC8773B8301E|rigid:anlIPjkwcywK1dR49VT++yFi9PQ false sufficient binding region:1-257("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q9NPC6 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-746712|uniprotkb:O43415|uniprotkb:Q9HB92|ensembl:ENSP00000306997 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:myoz2_human(display_long)|uniprotkb:Calsarcin-1(gene name synonym)|uniprotkb:FATZ-related protein 2(gene name synonym)|uniprotkb:MYOZ2(gene name)|psi-mi:MYOZ2(display_short)|uniprotkb:C4orf5(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089770|imex:IM-21827-113 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_057683.1|ensembl:ENSG00000172399(gene)|ensembl:ENST00000307128(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003779"(actin binding)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030346"(protein phosphatase 2B binding)|go:"GO:0031433"(telethonin binding)|go:"GO:0043503"(skeletal muscle fiber adaptation)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051373"(FATZ binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR008438(Calcineurin-binding)|uniprotkb:Q9NPC6(identity)|ddbj/embl/genbank:BC017402(identity)|entrezgene/locuslink:51778(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:Y2B5tDM2oGscI8xiTwB69hFEhL89606 intact-crc:C9EA9438A1389EC3|rigid:A0pDW6BPXG3VONVxCllJNhSBuGc false sufficient binding region:1-257("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q9NTN9-3 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9089805|ensembl:ENSP00000430175 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:q9ntn9-3(display_long)|uniprotkb:KIAA1619(gene name synonym)|uniprotkb:SEMA4G(gene name)|psi-mi:SEMA4G(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089802|imex:IM-21827-115 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) intact:EBI-6447340(isoform-parent)|ensembl:ENSG00000095539(gene)|ensembl:ENST00000517724(transcript)|uniprotkb:Q9NTN9-3(isoform-parent)|uniprotkb:Q9NTN9-3(identity)|ddbj/embl/genbank:BC020960(identity)|entrezgene/locuslink:57715(identity) psi-mi:"MI:0469"(intact) - isoform-comment:No experimental confirmation available. figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:JvIOPLyz067PteoMxbO8lbEMuwM9606 intact-crc:4971578F54F9BC8C|rigid:co9jXN3qL4cXxwixnJhfRnSl5KE false sufficient binding region:1-257("MI:0442") sufficient binding region:576-702("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q9UHC1-2 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9089845|ensembl:ENSP00000370355 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:q9uhc1-2(display_long)|uniprotkb:MutL protein homolog 3(gene name synonym)|uniprotkb:MLH3(gene name)|psi-mi:MLH3(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089850|imex:IM-21827-117 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) intact:EBI-3893094(isoform-parent)|ensembl:ENSG00000119684(gene)|ensembl:ENST00000380968(transcript)|uniprotkb:Q9UHC1-2(isoform-parent)|uniprotkb:Q9UHC1-2(identity)|entrezgene/locuslink:27030(identity)|ddbj/embl/genbank:BC112167(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:oe65NaIo0F4GdG1T6Cevbp4xaTQ9606 intact-crc:5DBCFB459D0D177E|rigid:EA8XGZAKnl1kfB+OOwZAb1OZNaA false sufficient binding region:1-257("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q9UF11-4 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9089825|ensembl:ENSP00000227214|ensembl:ENSP00000442616 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:q9uf11-4(display_long)|uniprotkb:EVT1(gene name synonym)|uniprotkb:Evectin-1(gene name synonym)|uniprotkb:KPL1(gene name synonym)|uniprotkb:PH domain-containing protein in retina 1(gene name synonym)|uniprotkb:PHR1(gene name synonym)|uniprotkb:PHRET1(gene name synonym)|uniprotkb:Pleckstrin homology domain retinal protein 1(gene name synonym)|uniprotkb:PLEKHB1(gene name)|psi-mi:PLEKHB1(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089829|imex:IM-21827-116 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) intact:EBI-6447271(isoform-parent)|ensembl:ENSG00000021300(gene)|ensembl:ENST00000227214(transcript)|ensembl:ENST00000535129(transcript)|uniprotkb:Q9UF11-4(identity)|entrezgene/locuslink:58473(identity)|ddbj/embl/genbank:BC008075(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:5RmF2rJLHJT3yM6ZP4+m7unTGNs9606 intact-crc:A3AD9A7CE467C2B0|rigid:13anCpPEJYiB0tB5LzQ9S5O5LCI false sufficient binding region:1-257("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q9UHY8 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-396453|uniprotkb:Q76LN0|uniprotkb:Q99690|uniprotkb:Q5EBN3|intact:EBI-28984869|ensembl:ENSP00000385112 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:fez2_human(display_long)|uniprotkb:FEZ2(gene name)|psi-mi:FEZ2(display_short)|uniprotkb:Zygin-2(gene name synonym)|uniprotkb:Zygin II(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089866|imex:IM-21827-118 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_001036013.1|refseq:NP_005093.2|ensembl:ENST00000379245|ensembl:ENSP00000368547|ensembl:ENSP00000385112|ensembl:ENSG00000171055(gene)|ensembl:ENST00000405912(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0030424"(axon)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR011680(FEZ-like)|interpro:IPR015641(Fasciculation and elongation protein zeta 2)|mint:Q9UHY8|uniprotkb:Q9UHY8(identity)|ddbj/embl/genbank:BC110386(identity)|entrezgene/locuslink:9637(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:n5uH+vdgrrvmI+PYkcMUEnAzxwE9606 intact-crc:B55D3D3E7A986DC9|rigid:GO+MMpsXWNWtmeuSVCaqXwlLXpU false sufficient binding region:1-257("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:P28347 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-529156|intact:EBI-9089898|uniprotkb:A4FUP2|uniprotkb:E7EV65|intact:EBI-11138289|ensembl:ENSP00000435233 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:tead1_human(display_long)|uniprotkb:TEA domain family member 1(gene name synonym)|uniprotkb:Protein GT-IIC(gene name synonym)|uniprotkb:Transcription factor 13(gene name synonym)|uniprotkb:NTEF-1(gene name synonym)|uniprotkb:TEAD1(gene name)|psi-mi:TEAD1(display_short)|uniprotkb:TCF13(gene name synonym)|uniprotkb:TEF1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089903|imex:IM-21827-120 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_068780.2|dip:DIP-34360N|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035329"(hippo signaling)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048568"(embryonic organ development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0140552"(TEAD-YAP complex)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000818(TEA/ATTS)|interpro:IPR016361(Transcriptional enhancer factor)|interpro:IPR038096|interpro:IPR041086|rcsb pdb:2HZD|rcsb pdb:3KYS|rcsb pdb:4RE1|rcsb pdb:4Z8E|rcsb pdb:5NNX|rcsb pdb:6HIL|rcsb pdb:6IM5|rcsb pdb:7CMM|reactome:R-HSA-2032785|reactome:R-HSA-8951671|reactome:R-HSA-9619665|ensembl:ENSG00000187079(gene)|ensembl:ENST00000527636(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|uniprotkb:A4FUP2(identity)|entrezgene/locuslink:7003(identity)|ddbj/embl/genbank:BC115398(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2015/09/01 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:NIFPFGqbBqT0PRutdwX8TJ4v/AE9606 intact-crc:BF7234A46231407C|rigid:4R73HxHSk849chmYfwSwXCzDtIE false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 intact:EBI-9087225 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 - psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:dkfzp566h0824_human(display_short)|psi-mi:EBI-9087225(display_long) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089919|imex:IM-21827-121 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) entrezgene/locuslink:54744(identity)|genbank_nucl_gi:BC104430(identity)|intact:EBI-9087225(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:TMByLiegs1ereBw2iiSBR0Mtpnc9606 intact-crc:FEA7D76C82D26B1A|rigid:6zzzISS4rt93ikvYpro5c41DexY false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G3V1X1 uniprotkb:Q8IUH5 intact:EBI-6448783|ensembl:ENSP00000447976 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:g3v1x1_human(display_long)|uniprotkb:PSRC2(gene name synonym)|uniprotkb:hCG_25411(orf name)|uniprotkb:ZFC3H1(gene name)|psi-mi:ZFC3H1(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089933|imex:IM-21827-122 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000133858(gene)|ensembl:ENST00000552037(transcript)|interpro:IPR039278|uniprotkb:G3V1X1(identity)|ddbj/embl/genbank:BC015679(identity)|entrezgene/locuslink:196441(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:c9IRrxnUqSzFGE7w1sZ+8bIaMjo9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:6C203B2368EB427A|rigid:+5Bw+04RINTobv5geWFaeVCSUvE false - sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:O00161 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-745000|uniprotkb:O00162|uniprotkb:Q13602|uniprotkb:Q6IAE3|ensembl:ENSP00000249647 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:snp23_human(display_long)|uniprotkb:Vesicle-membrane fusion protein SNAP-23(gene name synonym)|uniprotkb:SNAP23(gene name)|psi-mi:SNAP23(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089949|imex:IM-21827-123 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_003816.2|refseq:NP_570710.1|ensembl:ENSG00000092531(gene)|ensembl:ENST00000249647(transcript)|go:"GO:0002553"(histamine secretion by mast cell)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006887"(exocytosis)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006903"(vesicle targeting)|go:"GO:0006906"(vesicle fusion)|go:"GO:0015031"(protein transport)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042581"(specific granule)|go:"GO:0042582"(azurophil granule)|go:"GO:0043005"(neuron projection)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0098793"(presynapse)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR000928(SNAP-25)|mint:O00161|rcsb pdb:1NHL|rcsb pdb:3ZUS|reactome:R-HSA-1445148|reactome:R-HSA-199992|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-1236974|uniprotkb:O00161(identity)|ddbj/embl/genbank:BC003686(identity)|entrezgene/locuslink:8773(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:8ZcXbqhusSijGdekDMdkZA5DejY9606 intact-crc:60C36D21C6A0830F|rigid:McBJa6jHMsQGoi4iaYvZ9HHfNCE false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y605 uniprotkb:Q8IUH5 intact:EBI-995714|uniprotkb:B3KVT2|ensembl:ENSP00000318352|ensembl:ENSP00000372024|ensembl:ENSP00000422065|uniprotkb:D3DVT3 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:mofa1_human(display_long)|uniprotkb:PGR1(gene name synonym)|uniprotkb:Protein PGR1(gene name synonym)|uniprotkb:Protein associated with MRG of 14 kDa(gene name synonym)|uniprotkb:MRFAP1(gene name)|psi-mi:MRFAP1(display_short)|uniprotkb:PAM14(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089882|imex:IM-21827-119 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_150638.1|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR029254|mint:Q9Y605|ensembl:ENSG00000179010(gene)|ensembl:ENST00000320912(transcript)|ensembl:ENST00000382581(transcript)|ensembl:ENST00000507420(transcript)|go:"GO:0005654"(nucleoplasm)|refseq:NP_001258982.1|uniprotkb:Q9Y605(identity)|entrezgene/locuslink:93621(identity)|ddbj/embl/genbank:BC022797(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:qsRG2MjlSzgcyuUj0/45kBNrfw89606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:B06D41DD6FF5C8AF|rigid:gdfeS3JGz/FKpFkMJdbM0arE86Q false - sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O75409 uniprotkb:Q8IUH5 intact:EBI-6447217|intact:EBI-9090017|ensembl:ENSP00000339511|uniprotkb:A1A4D3 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:hypm_human(display_long)|uniprotkb:H2AP(gene name)|psi-mi:H2AP(display_short)|uniprotkb:CXorf27(gene name synonym)|uniprotkb:HYPM(gene name synonym)|uniprotkb:Histone H2A.P(gene name synonym)|uniprotkb:Huntingtin yeast partner M(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090022|imex:IM-21827-127 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000187516(gene)|ensembl:ENST00000341016(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR009072(Histone-fold)|refseq:NP_036406.1|uniprotkb:O75409(identity)|entrezgene/locuslink:25763(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:tYJhmOh8HrAip5T60fLAvOU+wB89606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:44D31327AA8CDADB|rigid:amSZ9C4AYaU410pjR3fiJkLyPfw false - sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43365 uniprotkb:Q8IUH5 intact:EBI-8643838|ensembl:ENSP00000324884|ensembl:ENSP00000379640|ensembl:ENSP00000484411|uniprotkb:A4D181|intact:MINT-8163379 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:hxa3_human(display_long)|uniprotkb:HOXA3(gene name)|psi-mi:HOXA3(display_short)|uniprotkb:HOX1E(gene name synonym)|uniprotkb:Homeobox protein Hox-1E(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090001|imex:IM-21827-126 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105997(gene)|ensembl:ENST00000317201(transcript)|ensembl:ENST00000396352(transcript)|ensembl:ENST00000612286(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010159"(specification of animal organ position)|go:"GO:0010467"(gene expression)|go:"GO:0021615"(glossopharyngeal nerve morphogenesis)|go:"GO:0030878"(thyroid gland development)|go:"GO:0048538"(thymus development)|go:"GO:0048645"(animal organ formation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051216"(cartilage development)|go:"GO:0060017"(parathyroid gland development)|go:"GO:0071837"(HMG box domain binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR025281|reactome:R-HSA-5617472|refseq:XP_011513645.1|refseq:XP_005249787.1|refseq:XP_005249788.1|refseq:XP_005249789.1|refseq:NP_109377.1|refseq:NP_705895.1|refseq:XP_006715778.1|uniprotkb:O43365(identity)|entrezgene/locuslink:3200(identity)|ddbj/embl/genbank:BC015180(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) comment:mint - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:7gP6b03wtjUhsVpcwdjdrUtQj4Y9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:40D8657A6B2D2597|rigid:VuFNGwrTwU1Any87hxpAYGTFtE8 false - sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:O15535 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-751531|uniprotkb:Q2TTR1|uniprotkb:B4E1W6|uniprotkb:E7EVQ2|ensembl:ENSP00000252207|ensembl:ENSP00000433402 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:zsc9_human(display_long)|uniprotkb:ZSCAN9(gene name)|psi-mi:ZSCAN9(display_short)|uniprotkb:Cell proliferation-inducing gene 12 protein(gene name synonym)|uniprotkb:PRD51(gene name synonym)|uniprotkb:ZNF193(gene name synonym)|uniprotkb:Zinc finger protein 193(gene name synonym)|uniprotkb:PIG12(orf name) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089985|imex:IM-21827-125 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_001186409.1|refseq:NP_006290.1|refseq:NP_001186408.1|refseq:XP_016866756.1|ensembl:ENSG00000137185(gene)|ensembl:ENST00000252207(transcript)|ensembl:ENST00000531979(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|mint:O15535|uniprotkb:O15535(identity)|ddbj/embl/genbank:BC010374(identity)|entrezgene/locuslink:7746(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:NpEnjqbpSwof7YWBbMvQlSvkdeM9606 intact-crc:8E3675C3E2D9D49D|rigid:YyL9jsPzn+9mMr6ut2ajET3k9HE false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:O14662-5 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9089968|ensembl:ENSP00000350723 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:o14662-5(display_long)|uniprotkb:STX16(gene name)|psi-mi:STX16(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9089965|imex:IM-21827-124 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) intact:EBI-2853548(isoform-parent)|uniprotkb:O14662-5(isoform-parent)|ensembl:ENSG00000124222(gene)|ensembl:ENST00000358029(transcript)|uniprotkb:O14662-5(identity)|ddbj/embl/genbank:BC073876(identity)|entrezgene/locuslink:8675(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:LgDkJR9MFld/EZpYXshiQmnJKOE9606 intact-crc:D3D0EFAC0B7C8D3B|rigid:h7A1lwP7MsHU5/3HRMpNkMKBC8c false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:O94876 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-2820525|uniprotkb:Q8IXM8|uniprotkb:Q68E06|uniprotkb:A8K5Y3|uniprotkb:B4DE04|ensembl:ENSP00000376930 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:tmcc1_human(display_long)|uniprotkb:TMCC1(gene name)|psi-mi:TMCC1(display_short)|uniprotkb:KIAA0779(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090053|imex:IM-21827-129 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:XP_011510874.1|refseq:XP_011510875.1|refseq:XP_011510878.1|refseq:XP_011510881.1|refseq:XP_011510884.1|refseq:NP_001017395.2|refseq:NP_001121696.1|refseq:XP_016861420.1|refseq:XP_016861421.1|refseq:XP_016861422.1|ensembl:ENSG00000172765(gene)|ensembl:ENST00000393238(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0090148"(membrane fission)|go:"GO:0097750"(endosome membrane tubulation)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|go:"GO:0140285"(endosome fission)|interpro:IPR019394|refseq:XP_006713605.1|refseq:XP_006713606.1|refseq:XP_006713607.1|uniprotkb:O94876(identity)|entrezgene/locuslink:23023(identity)|ddbj/embl/genbank:BC039859(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:gxHP7LGKWajp9+7rW6Llm1pNhTY9606 intact-crc:5EA3121377043742|rigid:e8EuxLqvimscHUV+DVUhv9hemV4 false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O95070 uniprotkb:Q8IUH5 intact:EBI-2799703|uniprotkb:Q9BVD0|uniprotkb:A6NM00|uniprotkb:Q96G83|ensembl:ENSP00000366098 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:yif1a_human(display_long)|uniprotkb:54TM(gene name synonym)|uniprotkb:HYIF1P(gene name synonym)|uniprotkb:YIF1(gene name synonym)|uniprotkb:54TMp(gene name synonym)|uniprotkb:YIP1-interacting factor homolog A(gene name synonym)|uniprotkb:YIF1A(gene name)|psi-mi:YIF1A(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090069|imex:IM-21827-130 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065203.2|ensembl:ENSG00000174851(gene)|ensembl:ENST00000376901(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR005578(Hrf1)|mint:O95070|reactome:R-HSA-381038|uniprotkb:O95070(identity)|entrezgene/locuslink:10897(identity)|ddbj/embl/genbank:BC001299(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:udkO5o876pUyTxBnhOchiirpW0U9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:E4D43EE7CF869659|rigid:KvJheMiAQzaQ2/Z9DA9VCKouwEE false - sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O76041 uniprotkb:Q8IUH5 intact:EBI-2880203|ensembl:ENSP00000366326|uniprotkb:B0YJ45|uniprotkb:Q2TBD0|uniprotkb:Q9UIC4|uniprotkb:B9EIM9|uniprotkb:E9PRX7|uniprotkb:Q5VZT2|uniprotkb:Q70I54 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:nebl_human(display_long)|uniprotkb:NEBL(gene name)|psi-mi:NEBL(display_short)|uniprotkb:Actin-binding Z-disk protein(gene name synonym)|uniprotkb:LNEBL(gene name synonym)|uniprotkb:C10orf113(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090037|imex:IM-21827-128 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000078114(gene)|ensembl:ENST00000377122(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0030018"(Z disc)|go:"GO:0031005"(filamin binding)|go:"GO:0031674"(I band)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071691"(cardiac muscle thin filament assembly)|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035631|interpro:IPR036028|mint:O76041|rcsb pdb:4F14|refseq:NP_006384.1|refseq:NP_001166955.1|refseq:NP_998734.1|uniprotkb:O76041(identity)|ddbj/embl/genbank:BC110453(identity)|entrezgene/locuslink:10529(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:6+3t3OOFerBzWUyX3qtfz4DhFdg9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:37F56EF4AD527C88|rigid:fWlm+v1ypD2jkFhMp8TIbI+Ky5U false - sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O95447 uniprotkb:Q8IUH5 intact:EBI-8473670|intact:MINT-8417687|uniprotkb:D3DSI0|uniprotkb:Q3ZCT0|ensembl:ENSP00000288350|ensembl:ENSP00000351008|ensembl:ENSP00000370046 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:lca5l_human(display_long)|uniprotkb:LCA5L(gene name)|psi-mi:LCA5L(display_short)|uniprotkb:C21orf13(gene name synonym)|uniprotkb:Leber congenital amaurosis 5-like protein(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090085|imex:IM-21827-131 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_689718.1|refseq:XP_005260983.1|refseq:XP_006724030.1|ensembl:ENSG00000157578(gene)|ensembl:ENST00000288350(transcript)|ensembl:ENST00000358268(transcript)|ensembl:ENST00000380671(transcript)|go:"GO:0005930"(axoneme)|go:"GO:0042073"(intraciliary transport)|interpro:IPR026188|interpro:IPR028933|mint:O95447|uniprotkb:O95447(identity)|entrezgene/locuslink:150082(identity)|ddbj/embl/genbank:BC031059(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) comment:mint|comment:homomint - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:QOk97i8f0RT79mI/23vOyMFt/Ec9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:7F1F936922F53322|rigid:v+bcSm1SAbZQawUmHwHB+EhwWKQ false - sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P01040 uniprotkb:Q8IUH5 intact:EBI-724303|ensembl:ENSP00000264474|uniprotkb:Q6IB90 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:cyta_human(display_long)|uniprotkb:Cystatin-AS(gene name synonym)|uniprotkb:Stefin-A(gene name synonym)|uniprotkb:CSTA(gene name)|psi-mi:CSTA(display_short)|uniprotkb:STF1(gene name synonym)|uniprotkb:STFA(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090101|imex:IM-21827-132 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005204.1|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR001713(Proteinase inhibitor I25A, stefin A)|mint:P01040|rcsb pdb:1CYU|rcsb pdb:1CYV|rcsb pdb:1DVC|rcsb pdb:1DVD|rcsb pdb:1GD3|rcsb pdb:1GD4|rcsb pdb:1N9J|rcsb pdb:1NB3|rcsb pdb:1NB5|rcsb pdb:3K9M|rcsb pdb:3KFQ|interpro:IPR018073|rcsb pdb:3KSE|reactome:R-HSA-6809371|ensembl:ENSG00000121552(gene)|ensembl:ENST00000264474(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002020"(protease binding)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010466"(negative regulation of peptidase activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0045861"(negative regulation of proteolysis)|uniprotkb:P01040(identity)|ddbj/embl/genbank:BC010379(identity)|entrezgene/locuslink:1475(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:SzbpyWUHlOtItIvffzuwhcqFsDI9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:A6F9BFE84ECDD2C3|rigid:5GcJ1qow2dum2sVALKOHSXn1nU0 false - sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P01116-2 uniprotkb:Q8IUH5 intact:EBI-367427|uniprotkb:P01118-1|ensembl:ENSP00000308495 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:p01116-2(display_long)|uniprotkb:KRAS(gene name)|psi-mi:KRAS(display_short)|uniprotkb:KRAS2(gene name synonym)|uniprotkb:RASK2(gene name synonym)|uniprotkb:K-Ras 2(gene name synonym)|uniprotkb:Ki-Ras(gene name synonym)|uniprotkb:c-K-ras(gene name synonym)|uniprotkb:c-Ki-ras(gene name synonym)|uniprotkb:K-Ras4B(isoform synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090117|imex:IM-21827-133 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-367415(rask_human)|ensembl:ENSG00000133703(gene)|ensembl:ENST00000311936(transcript)|uniprotkb:P01116-2(isoform-parent)|uniprotkb:P01116-2(identity)|ddbj/embl/genbank:BC013572(identity)|entrezgene/locuslink:3845(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) isoform-comment:"Variant in position: 152:V->G (in NS3). Variant in position: 153:D->V (in CFC2 and NS3, exhibits only minor alterations in its in vitro biochemical behavior compared to wild-type protein). Variant in position: 156:F->I (in NS3/CFC2). Variant in position: 156:F->L (found in a patient with Costello syndrome, exhibits an increase in intrinsic and guanine nucleotide exchange factor catalyzed nucleotide exchange in combination with an impaired GTPase-activating protein-stimulated GTP hydrolysis but functional in interaction with effectors)." - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:vHSaLYCo0d2r24erApiG/TCTmBc9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:A85AB997D8AAADDB|rigid:xCLJQeVSPwDqW25CelOAb9XjSis false - sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P04439 uniprotkb:Q8IUH5 intact:EBI-1042870|uniprotkb:O02963|uniprotkb:O78073|uniprotkb:P79563|uniprotkb:Q30208|uniprotkb:Q31623|uniprotkb:Q95377|uniprotkb:Q9BD15|uniprotkb:Q9BD19|uniprotkb:Q9MW42|uniprotkb:Q9TQK5|ensembl:ENSP00000366005|ensembl:ENSP00000379873|intact:EBI-1050524|intact:EBI-1049899|intact:EBI-2839447|intact:EBI-1044129|intact:EBI-8770309|intact:EBI-21249599|uniprotkb:B1PKZ3|uniprotkb:O02939|uniprotkb:O02954|uniprotkb:O02955|uniprotkb:O19509|uniprotkb:O19546|uniprotkb:O19598|uniprotkb:O19605|uniprotkb:O19606|uniprotkb:O19619|uniprotkb:O19647|uniprotkb:O19673|uniprotkb:O19687|uniprotkb:O19695|uniprotkb:O19756|uniprotkb:O19794|uniprotkb:O19795|uniprotkb:O43906|uniprotkb:O43907|uniprotkb:O46874|uniprotkb:O62921|uniprotkb:O62924|uniprotkb:O77937|uniprotkb:O77938|uniprotkb:O77964|uniprotkb:O78171|uniprotkb:O98009|uniprotkb:P30455|uniprotkb:P30456|uniprotkb:P30457|uniprotkb:P30458|uniprotkb:O98010|uniprotkb:O98011|uniprotkb:O98137|uniprotkb:P01891|uniprotkb:P01892|uniprotkb:P05534|uniprotkb:P06338|uniprotkb:P10313|uniprotkb:P10314|uniprotkb:P10315|uniprotkb:P10316|uniprotkb:P13746|uniprotkb:P16188|uniprotkb:P16189|uniprotkb:P16190|uniprotkb:P18462|uniprotkb:P30443|uniprotkb:P30444|uniprotkb:P30445|uniprotkb:P30446|uniprotkb:P30447|uniprotkb:P30448|uniprotkb:P30449|uniprotkb:P30450|uniprotkb:P30451|uniprotkb:P30514|uniprotkb:P79505|uniprotkb:P79562|uniprotkb:Q09160|uniprotkb:Q29680|uniprotkb:P30512|uniprotkb:Q29747|uniprotkb:Q29835|uniprotkb:Q29837|uniprotkb:Q29838|uniprotkb:Q29899|uniprotkb:Q29908|uniprotkb:Q29909|uniprotkb:Q29910|uniprotkb:Q5S3G1|uniprotkb:Q65A82|uniprotkb:Q8MHM1|uniprotkb:Q8MHN9|uniprotkb:Q95352|uniprotkb:Q95355|uniprotkb:P30452|uniprotkb:P30459|uniprotkb:Q95380|uniprotkb:Q95IZ5|uniprotkb:Q9BCN0|uniprotkb:Q9GJE6|uniprotkb:Q9GJE7|uniprotkb:Q9GJE8|uniprotkb:Q9MY89|uniprotkb:Q9MYA3|uniprotkb:Q9MYA5|uniprotkb:Q9MYC4|uniprotkb:Q9MYE6|uniprotkb:Q9MYE9|uniprotkb:Q9MYG4|uniprotkb:Q9MYG5|uniprotkb:Q9MYI5|uniprotkb:Q9TP25|uniprotkb:Q9TPQ3|uniprotkb:Q9TPR8|uniprotkb:Q9TPX8|uniprotkb:Q9TPX9|uniprotkb:Q9TPY0|uniprotkb:Q95362|uniprotkb:Q9TQ24|uniprotkb:Q9TQE8|uniprotkb:Q9TQE9|uniprotkb:Q9TQF1|uniprotkb:Q9TQF5|uniprotkb:Q9TQF8|uniprotkb:Q9TQF9|uniprotkb:Q9TQG0|uniprotkb:Q9TQG5|uniprotkb:Q9TQG7|uniprotkb:Q9TQH5|uniprotkb:Q9TQI3|uniprotkb:Q9TQM6|uniprotkb:Q9TQN5|uniprotkb:Q9TQP5|uniprotkb:Q9TQP6|uniprotkb:Q9TQP7|uniprotkb:Q9UIN1|uniprotkb:Q9UIN2|uniprotkb:Q9UIP7|uniprotkb:Q9UQU3|uniprotkb:Q9UQU6|uniprotkb:Q9UQU7|uniprotkb:P30453|uniprotkb:P30454|intact:EBI-1050350|intact:EBI-21505155 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:hlaa_human(display_long)|uniprotkb:HLA-A(gene name)|psi-mi:HLA-A(display_short)|uniprotkb:HLAA(gene name synonym)|uniprotkb:Human leukocyte antigen A(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090133|imex:IM-21827-134 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000376809(transcript)|ensembl:ENST00000396634(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001913"(T cell mediated cytotoxicity)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002419"(T cell mediated cytotoxicity directed against tumor cell target)|go:"GO:0002485"(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent)|go:"GO:0002486"(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0009986"(cell surface)|ensembl:ENSG00000206503(gene)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016045"(detection of bacterium)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030881"(beta-2-microglobulin binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0036037"(CD8-positive, alpha-beta T cell activation)|go:"GO:0042270"(protection from natural killer cell mediated cytotoxicity)|go:"GO:0042590"(antigen processing and presentation of exogenous peptide antigen via MHC class I)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042610"(CD8 receptor binding)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0045087"(innate immune response)|go:"GO:0046977"(TAP binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0062061"(TAP complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:2000566"(positive regulation of CD8-positive, alpha-beta T cell proliferation)|go:"GO:2000568"(positive regulation of memory T cell activation)|go:"GO:2001187"(positive regulation of CD8-positive, alpha-beta T cell activation)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|go:"GO:0050830"(defense response to Gram-positive bacterium)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|mint:P04439|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1AQD|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1Q94|rcsb pdb:1QEW|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1QVO|rcsb pdb:1S8D|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1T1W|rcsb pdb:1T1X|rcsb pdb:1T1Y|rcsb pdb:1T1Z|rcsb pdb:1T20|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1TMC|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1UR7|rcsb pdb:1W72|rcsb pdb:1X7Q|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2BCK|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2C7U|rcsb pdb:2CLR|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2GIT|rcsb pdb:1P7Q|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1HSB|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1JF1|rcsb pdb:1JHT|rcsb pdb:1LP9|rcsb pdb:1OGA|rcsb pdb:5HGH|rcsb pdb:5HHM|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|rcsb pdb:5HYJ|rcsb pdb:5IRO|rcsb pdb:5ISZ|rcsb pdb:5JHD|rcsb pdb:5JZI|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:5N1Y|rcsb pdb:5N6B|rcsb pdb:5NHT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MGT|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MYJ|rcsb pdb:3NFN|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:3QFD|rcsb pdb:3QFJ|rcsb pdb:3QZW|rcsb pdb:3REW|rcsb pdb:3RL1|rcsb pdb:3RL2|rcsb pdb:3TO2|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:3VXM|rcsb pdb:3VXN|rcsb pdb:3VXO|rcsb pdb:3VXP|rcsb pdb:3VXR|rcsb pdb:3VXS|rcsb pdb:3VXU|rcsb pdb:3W0W|rcsb pdb:3WL9|rcsb pdb:3WLB|rcsb pdb:4E5X|rcsb pdb:4EMZ|rcsb pdb:4EN2|rcsb pdb:4EUP|rcsb pdb:4F7M|rcsb pdb:4F7P|rcsb pdb:4F7T|rcsb pdb:4FTV|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:4L3E|rcsb pdb:4MJ5|rcsb pdb:4MJ6|rcsb pdb:4MNQ|rcsb pdb:4N8V|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4NO3|rcsb pdb:4GKN|rcsb pdb:4NO5|rcsb pdb:4NQV|rcsb pdb:4NQX|rcsb pdb:4OV5|rcsb pdb:4QOK|rcsb pdb:4U6X|rcsb pdb:4GKS|rcsb pdb:4HWZ|rcsb pdb:4HX1|rcsb pdb:4U6Y|rcsb pdb:4UQ2|rcsb pdb:4UQ3|rcsb pdb:4I48|rcsb pdb:4WJ5|rcsb pdb:4I4W|rcsb pdb:4WU5|rcsb pdb:4JFD|rcsb pdb:4WU7|rcsb pdb:4WUU|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|rcsb pdb:4K7F|rcsb pdb:5BRZ|rcsb pdb:5BS0|rcsb pdb:5C07|rcsb pdb:5C08|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:5NQK|rcsb pdb:5SWQ|rcsb pdb:5TEZ|rcsb pdb:5W1W|rcsb pdb:5WJL|rcsb pdb:5WJN|rcsb pdb:5WKF|rcsb pdb:5WKH|rcsb pdb:5WSH|rcsb pdb:5WWI|rcsb pdb:5WWJ|rcsb pdb:5WWU|rcsb pdb:5WXC|rcsb pdb:5WXD|rcsb pdb:5XOV|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|rcsb pdb:6AT9|rcsb pdb:6D78|rcsb pdb:6D7G|rcsb pdb:6DKP|rcsb pdb:6EI2|rcsb pdb:6ENY|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:5NME|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0C|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5E00|rcsb pdb:5E6I|rcsb pdb:5E9D|rcsb pdb:5ENW|rcsb pdb:5EOT|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:5EUO|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5GRD|rcsb pdb:5GRG|rcsb pdb:5GSD|rcsb pdb:5HGA|rcsb pdb:5HGB|rcsb pdb:5HGD|rcsb pdb:6EWA|rcsb pdb:6SS7|rcsb pdb:6SS8|rcsb pdb:6SS9|rcsb pdb:6SSA|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|reactome:R-HSA-198933|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-8866654|reactome:R-HSA-909733|reactome:R-HSA-983170|rcsb pdb:6RSY|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6G3J|rcsb pdb:6G3K|rcsb pdb:6ID4|rcsb pdb:6J1W|rcsb pdb:6J29|rcsb pdb:6J2A|rcsb pdb:6JOZ|rcsb pdb:6JP3|rcsb pdb:6MPP|rcsb pdb:6NCA|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6OPD|rcsb pdb:6PBH|rcsb pdb:6PTB|rcsb pdb:6PTE|rcsb pdb:6Q3K|rcsb pdb:6Q3S|rcsb pdb:6R2L|rcsb pdb:6RP9|rcsb pdb:6RPA|rcsb pdb:6RPB|rcsb pdb:2GUO|rcsb pdb:2HLA|rcsb pdb:2HN7|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PYE|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:2XPG|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3BO8|rcsb pdb:3D25|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3I6L|rcsb pdb:3IXA|rcsb pdb:3KLA|rcsb pdb:3MGO|refseq:NP_002107.3|refseq:NP_001229687.1|uniprotkb:P04439(identity)|entrezgene/locuslink:3105(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2019/11/11 rogid:RNvdwEiEB2h1Qfvd4BEIKiGzw1s9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:B2D028BA56350F11|rigid:olsG5zFToYkBl8lUTz4woLkJB1o false - sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P08397 uniprotkb:Q8IUH5 intact:EBI-9090148|uniprotkb:G3V1P4|uniprotkb:G5EA58|uniprotkb:A8K2L0|uniprotkb:Q16012|uniprotkb:P08396|ensembl:ENSP00000498786 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:hem3_human(display_long)|uniprotkb:Hydroxymethylbilane synthase(gene name synonym)|uniprotkb:PBGD(gene name synonym)|uniprotkb:Pre-uroporphyrinogen synthase(gene name synonym)|uniprotkb:UPS(gene name synonym)|uniprotkb:HMBS(gene name)|psi-mi:HMBS(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090157|imex:IM-21827-135 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000181.2|refseq:NP_001019553.1|refseq:NP_001245137.1|refseq:NP_001245138.1|refseq:XP_005271588.1|refseq:XP_005271589.1|refseq:XP_016873118.1|ensembl:ENSG00000256269(gene)|go:"GO:0004418"(hydroxymethylbilane synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006782"(protoporphyrinogen IX biosynthetic process)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0018160"(peptidyl-pyrromethane cofactor linkage)|interpro:IPR000860(Tetrapyrrole biosynthesis, hydroxymethylbilane synthase)|interpro:IPR022417|interpro:IPR022418|interpro:IPR022419|interpro:IPR036803|rcsb pdb:3ECR|ensembl:ENST00000652429(transcript)|rcsb pdb:5M6R|rcsb pdb:5M7F|rcsb pdb:7AAJ|rcsb pdb:7AAK|rcsb pdb:7CCX|rcsb pdb:7CCY|rcsb pdb:7CCZ|rcsb pdb:7CD0|reactome:R-HSA-189451|rcsb pdb:3EQ1|uniprotkb:P08397(identity)|entrezgene/locuslink:3145(identity)|ddbj/embl/genbank:BC008149(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:aTjyl498kJtf2NyY0oQFyz00ogc9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:2C9A56C6334CC273|rigid:+Bm0v3NtgdnCYC/Ep8mfeVQ8X7o false - sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:P15976-2 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9090198 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:p15976-2(display_long)|uniprotkb:ERYF1(gene name synonym)|uniprotkb:Eryf1(gene name synonym)|uniprotkb:GATA-binding factor 1(gene name synonym)|uniprotkb:GF1(gene name synonym)|uniprotkb:NF-E1 DNA-binding protein(gene name synonym)|uniprotkb:GATA1(gene name)|psi-mi:GATA1(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090202|imex:IM-21827-137 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) intact:EBI-3909284(isoform-parent)|uniprotkb:P15976-2(isoform-parent)|uniprotkb:P15976-2(identity)|ddbj/embl/genbank:BC009797(identity)|entrezgene/locuslink:2623(identity) psi-mi:"MI:0469"(intact) - isoform-comment:No experimental confirmation available. figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:k5zPlmC/k7yYWDjUKg+PE9fGlcE9606 intact-crc:84589125B97DDB86|rigid:6mZ3zCwkVn2IZm5Iid5huquh0jY false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:P17655 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-1028956|uniprotkb:Q16738|uniprotkb:Q6PJT3|uniprotkb:Q8WU26|uniprotkb:Q9HBB1|uniprotkb:A6NDG7|ensembl:ENSP00000295006|uniprotkb:B7ZA96|uniprotkb:E7ES58 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:can2_human(display_long)|uniprotkb:CAPN2(gene name)|psi-mi:CAPN2(display_short)|uniprotkb:CANPL2(gene name synonym)|uniprotkb:Calpain-2 large subunit(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase 2(gene name synonym)|uniprotkb:Calpain M-type(gene name synonym)|uniprotkb:Millimolar-calpain(gene name synonym)|uniprotkb:Calpain large polypeptide L2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090218|imex:IM-21827-138 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_001139540.1|refseq:NP_001739.2|ensembl:ENSG00000162909(gene)|ensembl:ENST00000295006(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001824"(blastocyst development)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006508"(proteolysis)|go:"GO:0007520"(myoblast fusion)|go:"GO:0007565"(female pregnancy)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031143"(pseudopodium)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0005634"(nucleus)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048266"(behavioral response to pain)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901741"(positive regulation of myoblast fusion)|go:"GO:2001247"(positive regulation of phosphatidylcholine biosynthetic process)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR001300(Peptidase C2, calpain)|go:"GO:0005737"(cytoplasm)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022682|interpro:IPR022683|interpro:IPR022684|interpro:IPR029539|interpro:IPR033883|interpro:IPR036213|interpro:IPR038765|interpro:IPR042736|mint:P17655|rcsb pdb:1KFU|rcsb pdb:1KFX|rcsb pdb:2NQA|reactome:R-HSA-1474228|reactome:R-HSA-8862803|interpro:IPR002048(Calcium-binding EF-hand)|uniprotkb:P17655(identity)|entrezgene/locuslink:824(identity)|ddbj/embl/genbank:BC021303(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:r60XX66kihGVLaa9888soeXjc0M9606 intact-crc:C38BE74E7068EF6F|rigid:T7f5rF5S5BsYb730MlW+3KGKdEY false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C870 uniprotkb:Q8IUH5 intact:EBI-9090173|uniprotkb:Q9UKV7|uniprotkb:Q8TB10|uniprotkb:A5D6V5|uniprotkb:Q59GF9|uniprotkb:O95712|ensembl:ENSP00000380467 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:jmjd7_human(display_long)|uniprotkb:Jumonji domain-containing protein 7(gene name synonym)|uniprotkb:JMJD7(gene name)|psi-mi:JMJD7(display_short)|uniprotkb:JmjC domain-containing protein 7(gene name synonym)|uniprotkb:"L-lysine (3S)-hydroxylase JMJD7"(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090182|imex:IM-21827-136 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001108104.1|ensembl:ENST00000397299(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR041667|mint:P0C870|rcsb pdb:5NFN|ensembl:ENSG00000243789(gene)|rcsb pdb:5NFO|uniprotkb:P0C870(identity)|ddbj/embl/genbank:BC025290(identity)|entrezgene/locuslink:8681(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:nEpqkRxJEXiQhXjje3BEwXVxKKE9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:C31977C0BFDD1D4F|rigid:u12eIQqTiFVg/aEbYuMWR0KmhwE false - sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:P26651 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-374248|intact:EBI-28988987|ensembl:ENSP00000469647|uniprotkb:B2RA54 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:ttp_human(display_long)|uniprotkb:ZFP36(gene name)|psi-mi:ZFP36(display_short)|uniprotkb:G0S24(gene name synonym)|uniprotkb:TIS11A(gene name synonym)|uniprotkb:TTP(gene name synonym)|uniprotkb:Growth factor-inducible nuclear protein NUP475(gene name synonym)|uniprotkb:G0/G1 switch regulatory protein 24(gene name synonym)|uniprotkb:NUP475(gene name synonym)|uniprotkb:Tristetraprolin(gene name synonym)|uniprotkb:Zinc finger protein 36(gene name synonym)|uniprotkb:RNF162A(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090266|imex:IM-21827-141 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) ensembl:ENSG00000128016(gene)|ensembl:ENST00000597629(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0009611"(response to wounding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010837"(regulation of keratinocyte proliferation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031086"(nuclear-transcribed mRNA catabolic process, deadenylation-independent decay)|go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0038066"(p38MAPK cascade)|go:"GO:0042594"(response to starvation)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045616"(regulation of keratinocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051028"(mRNA transport)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0097011"(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901835"(positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:1902172"(regulation of keratinocyte apoptotic process)|go:"GO:1904246"(negative regulation of polynucleotide adenylyltransferase activity)|go:"GO:1904582"(positive regulation of intracellular mRNA localization)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|rcsb pdb:4J8S|reactome:R-HSA-450513|refseq:NP_003398.2|ensembl:ENSP00000469647|dip:DIP-29845N|uniprotkb:P26651(identity)|ddbj/embl/genbank:BC009693(identity)|entrezgene/locuslink:7538(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:gDx8zP1NQwjgu7oJZg3sneBZnaI9606 intact-crc:52077B70E2EFD546|rigid:3dirkDUzSsSMx1nbbiZdviQUEyY false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:P20290-2 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-1054703|ensembl:ENSP00000338516 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:p20290-2(display_long)|uniprotkb:BTF3b(isoform synonym)|uniprotkb:BTF3(gene name)|psi-mi:BTF3(display_short)|uniprotkb:NACB(gene name synonym)|uniprotkb:RNA polymerase B transcription factor 3(gene name synonym)|uniprotkb:OK/SW-cl.8(orf name)|uniprotkb:Nascent polypeptide-associated complex subunit beta(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090234|imex:IM-21827-139 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) intact:EBI-1054687(btf3_human)|ensembl:ENSG00000145741(gene)|ensembl:ENST00000335895(transcript)|uniprotkb:P20290-2(isoform-parent)|uniprotkb:P20290-2(identity)|ddbj/embl/genbank:BC008062(identity)|entrezgene/locuslink:689(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:nViZ1CRkho2stQQ1ts0kUzwhOO09606 intact-crc:C8F486A3B279C94E|rigid:3zEvxCv/7Nw+1msqW440ziykFvc false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:P26641 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-351467|uniprotkb:Q6PJ62|uniprotkb:Q6PK31|uniprotkb:Q96CU2|uniprotkb:Q9P196|intact:EBI-2321928|uniprotkb:B4DTG2|ensembl:ENSP00000331901 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:ef1g_human(display_long)|uniprotkb:PRO1608(orf name)|uniprotkb:EEF1G(gene name)|psi-mi:EEF1G(display_short)|uniprotkb:EF1G(gene name synonym)|uniprotkb:eEF-1B gamma(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090250|imex:IM-21827-140 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_001395.1|ensembl:ENSG00000254772(gene)|ensembl:ENST00000329251(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006414"(translational elongation)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001662(Translation elongation factor EF1B, gamma chain, conserved)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR036433|interpro:IPR040079|mint:P26641|rcsb pdb:1PBU|rcsb pdb:5DQS|rcsb pdb:5JPO|reactome:R-HSA-156842|dip:DIP-32516N|uniprotkb:P26641(identity)|ddbj/embl/genbank:BC015813(identity)|entrezgene/locuslink:1937(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:biVN96umeEdPm/wvPN4VwbSRHTs9606 intact-crc:93175D3663F62931|rigid:V2h5YJnY1gRKxWbCAtcaVM2jq4g false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:P27986-2 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9090282|ensembl:ENSP00000338554 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:p27986-2(display_long)|uniprotkb:PIK3R1(gene name)|psi-mi:PIK3R1(display_short)|uniprotkb:GRB1(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha(gene name synonym)|uniprotkb:AS53(isoform synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090286|imex:IM-21827-142 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) ensembl:ENSG00000145675(gene)|ensembl:ENST00000336483(transcript)|intact:EBI-79464(isoform-parent)|uniprotkb:P27986-2(isoform-parent)|uniprotkb:P27986-2(identity)|entrezgene/locuslink:5295(identity)|ddbj/embl/genbank:BC030815(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:QtFCNbZABbNcR8Cd7rk+QMroFYM9606 intact-crc:4AB48C5B22B800F8|rigid:QgMDMGlVHDtrblv9qUN+FPUO5AI false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:P35520 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-740135|uniprotkb:Q99425|uniprotkb:Q9BWC5|uniprotkb:B2R993|uniprotkb:D3DSK4|intact:EBI-14245939|ensembl:ENSP00000344460|ensembl:ENSP00000352643|ensembl:ENSP00000381225|ensembl:ENSP00000381231 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:cbs_human(display_long)|uniprotkb:CBS(gene name)|psi-mi:CBS(display_short)|uniprotkb:Serine sulfhydrase(gene name synonym)|uniprotkb:Beta-thionase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090302|imex:IM-21827-143 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_000062.1|refseq:NP_001171479.1|refseq:NP_001171480.1|ensembl:ENSG00000160200(gene)|ensembl:ENST00000352178(transcript)|ensembl:ENST00000359624(transcript)|ensembl:ENST00000398158(transcript)|go:"GO:0004122"(cystathionine beta-synthase activity)|ensembl:ENST00000398165(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006535"(cysteine biosynthetic process from serine)|go:"GO:0006563"(L-serine metabolic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0019343"(cysteine biosynthetic process via cystathionine)|go:"GO:0019344"(cysteine biosynthetic process)|go:"GO:0019346"(transsulfuration)|go:"GO:0019448"(L-cysteine catabolic process)|go:"GO:0019825"(oxygen binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0020037"(heme binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042262"(DNA protection)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043418"(homocysteine catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050421"("nitrite reductase (NO-forming) activity")|go:"GO:0050667"(homocysteine metabolic process)|go:"GO:0070025"(carbon monoxide binding)|go:"GO:0070026"(nitric oxide binding)|go:"GO:0070814"(hydrogen sulfide biosynthetic process)|go:"GO:0072341"(modified amino acid binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001216(Cysteine synthase/cystathionine beta-synthase P-phosphate-binding site)|interpro:IPR001926(Pyridoxal phosphate-dependent enzyme, beta subunit)|interpro:IPR005857(Cystathionine beta-synthase)|interpro:IPR036052|mint:P35520|rcsb pdb:1JBQ|rcsb pdb:1M54|rcsb pdb:4COO|rcsb pdb:4L0D|rcsb pdb:4L27|rcsb pdb:4L28|rcsb pdb:4L3V|rcsb pdb:4PCU|rcsb pdb:4UUU|rcsb pdb:5MMS|reactome:R-HSA-1614603|reactome:R-HSA-2408508|refseq:XP_011528079.1|refseq:XP_011528083.1|refseq:XP_011528084.1|refseq:XP_011544396.1|refseq:XP_011544397.1|refseq:XP_011544399.1|refseq:XP_011544400.1|refseq:XP_011544401.1|refseq:NP_001307227.1|refseq:NP_001308002.1|refseq:XP_016883700.1|refseq:XP_016883701.1|refseq:XP_016883702.1|refseq:XP_016883703.1|refseq:XP_016883704.1|refseq:XP_016883705.1|refseq:XP_016883706.1|refseq:XP_016883707.1|refseq:XP_016883978.1|refseq:XP_016883979.1|refseq:XP_016883980.1|refseq:XP_016883981.1|uniprotkb:P35520(identity)|ddbj/embl/genbank:BC007257(identity)|entrezgene/locuslink:875(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:f9eo0cPOHppVY7Nqejag3YyK18s9606 intact-crc:EE702B27660E10D6|rigid:Ptx+i5+Poo6lOYWK2aKNmVuZKcc false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:P42025 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-367493|uniprotkb:Q53SK5|uniprotkb:Q9BRB7|uniprotkb:D3DVH2|ensembl:ENSP00000289228 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:acty_human(display_long)|uniprotkb:ACTR1B(gene name)|psi-mi:ACTR1B(display_short)|uniprotkb:Actin-related protein 1B(gene name synonym)|uniprotkb:CTRN2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090318|imex:IM-21827-144 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) ensembl:ENSG00000115073(gene)|ensembl:ENST00000289228(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P42025|reactome:R-HSA-2132295|reactome:R-HSA-6798695|refseq:NP_005726.1|uniprotkb:P42025(identity)|entrezgene/locuslink:10120(identity)|ddbj/embl/genbank:BC004374(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:FUpYgmLV3BdkZIlZGyC6L5kR+wE9606 intact-crc:9096365144CE08D4|rigid:bSdvZ+N8+uv9SqNCY0liuPm94Hw false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:P42858 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-466029|uniprotkb:Q9UQB7|ensembl:ENSP00000347184 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:hd_human(display_long)|uniprotkb:HTT(gene name)|psi-mi:HTT(display_short)|uniprotkb:IT15(gene name synonym)|uniprotkb:HD(gene name synonym)|uniprotkb:Huntington disease protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090373|imex:IM-21827-147 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) ensembl:ENSG00000197386(gene)|refseq:NP_002102.4|rcsb pdb:3IOV|rcsb pdb:3IOW|rcsb pdb:3LRH|rcsb pdb:4FE8|rcsb pdb:4FEB|rcsb pdb:4FEC|rcsb pdb:4FED|rcsb pdb:4RAV|rcsb pdb:6EZ8|rcsb pdb:6N8C|rcsb pdb:6RMH|rcsb pdb:6X9O|rcsb pdb:6YEJ|rcsb pdb:7DXJ|rcsb pdb:7DXK|reactome:R-HSA-9022692|ensembl:ENST00000355072(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006915"(apoptotic process)|go:"GO:0007030"(Golgi organization)|go:"GO:0016234"(inclusion body)|go:"GO:0019900"(kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0031648"(protein destabilization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034452"(dynactin binding)|go:"GO:0042297"(vocal learning)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0099111"(microtubule-based transport)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1904504"(positive regulation of lipophagy)|go:"GO:1905289"(regulation of CAMKK-AMPK signaling cascade)|go:"GO:1905337"(positive regulation of aggrephagy)|go:"GO:2000479"(regulation of cAMP-dependent protein kinase activity)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000091(Huntingtin)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|go:"GO:0000132"(establishment of mitotic spindle orientation)|interpro:IPR024613|interpro:IPR028426|mint:P42858|rcsb pdb:2D3X|rcsb pdb:2LD0|rcsb pdb:2LD2|rcsb pdb:3IO4|rcsb pdb:3IO6|rcsb pdb:3IOR|rcsb pdb:3IOT|rcsb pdb:3IOU|dip:DIP-32492N|uniprotkb:P42858(identity)|entrezgene/locuslink:3064(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:KyttHE2o2fORsw6iTh94LB7QShA9606 intact-crc:A62B1CA7B24CA5BC|rigid:lIR/BgNT+bjlRLM14OOqZl3D9Uw false sufficient binding region:64-487("MI:0442") sufficient binding region:1-506("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:P42858 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-466029|uniprotkb:Q9UQB7|ensembl:ENSP00000347184 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:hd_human(display_long)|uniprotkb:HTT(gene name)|psi-mi:HTT(display_short)|uniprotkb:IT15(gene name synonym)|uniprotkb:HD(gene name synonym)|uniprotkb:Huntington disease protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090355|imex:IM-21827-146 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) ensembl:ENSG00000197386(gene)|refseq:NP_002102.4|rcsb pdb:3IOV|rcsb pdb:3IOW|rcsb pdb:3LRH|rcsb pdb:4FE8|rcsb pdb:4FEB|rcsb pdb:4FEC|rcsb pdb:4FED|rcsb pdb:4RAV|rcsb pdb:6EZ8|rcsb pdb:6N8C|rcsb pdb:6RMH|rcsb pdb:6X9O|rcsb pdb:6YEJ|rcsb pdb:7DXJ|rcsb pdb:7DXK|reactome:R-HSA-9022692|ensembl:ENST00000355072(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006915"(apoptotic process)|go:"GO:0007030"(Golgi organization)|go:"GO:0016234"(inclusion body)|go:"GO:0019900"(kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0031648"(protein destabilization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034452"(dynactin binding)|go:"GO:0042297"(vocal learning)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0099111"(microtubule-based transport)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1904504"(positive regulation of lipophagy)|go:"GO:1905289"(regulation of CAMKK-AMPK signaling cascade)|go:"GO:1905337"(positive regulation of aggrephagy)|go:"GO:2000479"(regulation of cAMP-dependent protein kinase activity)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000091(Huntingtin)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|go:"GO:0000132"(establishment of mitotic spindle orientation)|interpro:IPR024613|interpro:IPR028426|mint:P42858|rcsb pdb:2D3X|rcsb pdb:2LD0|rcsb pdb:2LD2|rcsb pdb:3IO4|rcsb pdb:3IO6|rcsb pdb:3IOR|rcsb pdb:3IOT|rcsb pdb:3IOU|dip:DIP-32492N|uniprotkb:P42858(identity)|entrezgene/locuslink:3064(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:KyttHE2o2fORsw6iTh94LB7QShA9606 intact-crc:872921E4A8F68782|rigid:lIR/BgNT+bjlRLM14OOqZl3D9Uw false sufficient binding region:64-487("MI:0442") sufficient binding region:1-513("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:P42858 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-466029|uniprotkb:Q9UQB7|ensembl:ENSP00000347184 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:hd_human(display_long)|uniprotkb:HTT(gene name)|psi-mi:HTT(display_short)|uniprotkb:IT15(gene name synonym)|uniprotkb:HD(gene name synonym)|uniprotkb:Huntington disease protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090334|imex:IM-21827-145 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) ensembl:ENSG00000197386(gene)|refseq:NP_002102.4|rcsb pdb:3IOV|rcsb pdb:3IOW|rcsb pdb:3LRH|rcsb pdb:4FE8|rcsb pdb:4FEB|rcsb pdb:4FEC|rcsb pdb:4FED|rcsb pdb:4RAV|rcsb pdb:6EZ8|rcsb pdb:6N8C|rcsb pdb:6RMH|rcsb pdb:6X9O|rcsb pdb:6YEJ|rcsb pdb:7DXJ|rcsb pdb:7DXK|reactome:R-HSA-9022692|ensembl:ENST00000355072(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006915"(apoptotic process)|go:"GO:0007030"(Golgi organization)|go:"GO:0016234"(inclusion body)|go:"GO:0019900"(kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0031648"(protein destabilization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034452"(dynactin binding)|go:"GO:0042297"(vocal learning)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0099111"(microtubule-based transport)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1904504"(positive regulation of lipophagy)|go:"GO:1905289"(regulation of CAMKK-AMPK signaling cascade)|go:"GO:1905337"(positive regulation of aggrephagy)|go:"GO:2000479"(regulation of cAMP-dependent protein kinase activity)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000091(Huntingtin)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|go:"GO:0000132"(establishment of mitotic spindle orientation)|interpro:IPR024613|interpro:IPR028426|mint:P42858|rcsb pdb:2D3X|rcsb pdb:2LD0|rcsb pdb:2LD2|rcsb pdb:3IO4|rcsb pdb:3IO6|rcsb pdb:3IOR|rcsb pdb:3IOT|rcsb pdb:3IOU|dip:DIP-32492N|uniprotkb:P42858(identity)|entrezgene/locuslink:3064(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:KyttHE2o2fORsw6iTh94LB7QShA9606 intact-crc:3C860F1832764D98|rigid:lIR/BgNT+bjlRLM14OOqZl3D9Uw false sufficient binding region:64-487("MI:0442") sufficient binding region:1..1-87..87("MI:0442")|mutation:18..18-38..38("MI:0118") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P42858 uniprotkb:Q8IUH5 intact:EBI-466029|uniprotkb:Q9UQB7|ensembl:ENSP00000347184 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:hd_human(display_long)|uniprotkb:HTT(gene name)|psi-mi:HTT(display_short)|uniprotkb:IT15(gene name synonym)|uniprotkb:HD(gene name synonym)|uniprotkb:Huntington disease protein(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090412|imex:IM-21827-149 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000197386(gene)|refseq:NP_002102.4|rcsb pdb:3IOV|rcsb pdb:3IOW|rcsb pdb:3LRH|rcsb pdb:4FE8|rcsb pdb:4FEB|rcsb pdb:4FEC|rcsb pdb:4FED|rcsb pdb:4RAV|rcsb pdb:6EZ8|rcsb pdb:6N8C|rcsb pdb:6RMH|rcsb pdb:6X9O|rcsb pdb:6YEJ|rcsb pdb:7DXJ|rcsb pdb:7DXK|reactome:R-HSA-9022692|ensembl:ENST00000355072(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006915"(apoptotic process)|go:"GO:0007030"(Golgi organization)|go:"GO:0016234"(inclusion body)|go:"GO:0019900"(kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0031648"(protein destabilization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034452"(dynactin binding)|go:"GO:0042297"(vocal learning)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0099111"(microtubule-based transport)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1904504"(positive regulation of lipophagy)|go:"GO:1905289"(regulation of CAMKK-AMPK signaling cascade)|go:"GO:1905337"(positive regulation of aggrephagy)|go:"GO:2000479"(regulation of cAMP-dependent protein kinase activity)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000091(Huntingtin)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|go:"GO:0000132"(establishment of mitotic spindle orientation)|interpro:IPR024613|interpro:IPR028426|mint:P42858|rcsb pdb:2D3X|rcsb pdb:2LD0|rcsb pdb:2LD2|rcsb pdb:3IO4|rcsb pdb:3IO6|rcsb pdb:3IOR|rcsb pdb:3IOT|rcsb pdb:3IOU|dip:DIP-32492N|uniprotkb:P42858(identity)|entrezgene/locuslink:3064(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:KyttHE2o2fORsw6iTh94LB7QShA9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:7BF75D44F97ECABF|rigid:lIR/BgNT+bjlRLM14OOqZl3D9Uw false mutation:18..18-38..38("MI:0118")|sufficient binding region:1-513("MI:0442") sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:P42858 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-466029|uniprotkb:Q9UQB7|ensembl:ENSP00000347184 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:hd_human(display_long)|uniprotkb:HTT(gene name)|psi-mi:HTT(display_short)|uniprotkb:IT15(gene name synonym)|uniprotkb:HD(gene name synonym)|uniprotkb:Huntington disease protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090433|imex:IM-21827-150 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) ensembl:ENSG00000197386(gene)|refseq:NP_002102.4|rcsb pdb:3IOV|rcsb pdb:3IOW|rcsb pdb:3LRH|rcsb pdb:4FE8|rcsb pdb:4FEB|rcsb pdb:4FEC|rcsb pdb:4FED|rcsb pdb:4RAV|rcsb pdb:6EZ8|rcsb pdb:6N8C|rcsb pdb:6RMH|rcsb pdb:6X9O|rcsb pdb:6YEJ|rcsb pdb:7DXJ|rcsb pdb:7DXK|reactome:R-HSA-9022692|ensembl:ENST00000355072(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006915"(apoptotic process)|go:"GO:0007030"(Golgi organization)|go:"GO:0016234"(inclusion body)|go:"GO:0019900"(kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0031648"(protein destabilization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034452"(dynactin binding)|go:"GO:0042297"(vocal learning)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0099111"(microtubule-based transport)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1904504"(positive regulation of lipophagy)|go:"GO:1905289"(regulation of CAMKK-AMPK signaling cascade)|go:"GO:1905337"(positive regulation of aggrephagy)|go:"GO:2000479"(regulation of cAMP-dependent protein kinase activity)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000091(Huntingtin)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|go:"GO:0000132"(establishment of mitotic spindle orientation)|interpro:IPR024613|interpro:IPR028426|mint:P42858|rcsb pdb:2D3X|rcsb pdb:2LD0|rcsb pdb:2LD2|rcsb pdb:3IO4|rcsb pdb:3IO6|rcsb pdb:3IOR|rcsb pdb:3IOT|rcsb pdb:3IOU|dip:DIP-32492N|uniprotkb:P42858(identity)|entrezgene/locuslink:3064(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:KyttHE2o2fORsw6iTh94LB7QShA9606 intact-crc:9618734B38A6DE57|rigid:lIR/BgNT+bjlRLM14OOqZl3D9Uw false sufficient binding region:64-487("MI:0442") sufficient binding region:507-1230("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:P42858 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-466029|uniprotkb:Q9UQB7|ensembl:ENSP00000347184 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:hd_human(display_long)|uniprotkb:HTT(gene name)|psi-mi:HTT(display_short)|uniprotkb:IT15(gene name synonym)|uniprotkb:HD(gene name synonym)|uniprotkb:Huntington disease protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090391|imex:IM-21827-148 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) ensembl:ENSG00000197386(gene)|refseq:NP_002102.4|rcsb pdb:3IOV|rcsb pdb:3IOW|rcsb pdb:3LRH|rcsb pdb:4FE8|rcsb pdb:4FEB|rcsb pdb:4FEC|rcsb pdb:4FED|rcsb pdb:4RAV|rcsb pdb:6EZ8|rcsb pdb:6N8C|rcsb pdb:6RMH|rcsb pdb:6X9O|rcsb pdb:6YEJ|rcsb pdb:7DXJ|rcsb pdb:7DXK|reactome:R-HSA-9022692|ensembl:ENST00000355072(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006915"(apoptotic process)|go:"GO:0007030"(Golgi organization)|go:"GO:0016234"(inclusion body)|go:"GO:0019900"(kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0031648"(protein destabilization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034452"(dynactin binding)|go:"GO:0042297"(vocal learning)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0099111"(microtubule-based transport)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1904504"(positive regulation of lipophagy)|go:"GO:1905289"(regulation of CAMKK-AMPK signaling cascade)|go:"GO:1905337"(positive regulation of aggrephagy)|go:"GO:2000479"(regulation of cAMP-dependent protein kinase activity)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000091(Huntingtin)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|go:"GO:0000132"(establishment of mitotic spindle orientation)|interpro:IPR024613|interpro:IPR028426|mint:P42858|rcsb pdb:2D3X|rcsb pdb:2LD0|rcsb pdb:2LD2|rcsb pdb:3IO4|rcsb pdb:3IO6|rcsb pdb:3IOR|rcsb pdb:3IOT|rcsb pdb:3IOU|dip:DIP-32492N|uniprotkb:P42858(identity)|entrezgene/locuslink:3064(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:KyttHE2o2fORsw6iTh94LB7QShA9606 intact-crc:0B4770DAA442086B|rigid:lIR/BgNT+bjlRLM14OOqZl3D9Uw false sufficient binding region:64-487("MI:0442") sufficient binding region:1-513("MI:0442")|mutation:18..18-38..38("MI:0118") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:P49840 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-1044067|uniprotkb:O14959|ensembl:ENSP00000222330|ensembl:ENSP00000412663 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:gsk3a_human(display_long)|uniprotkb:GSK3A(gene name)|psi-mi:GSK3A(display_short)|uniprotkb:Serine/threonine-protein kinase GSK3A(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090467|imex:IM-21827-152 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) ensembl:ENSG00000105723(gene)|ensembl:ENST00000222330(transcript)|ensembl:ENST00000453535(transcript)|go:"GO:0003073"(regulation of systemic arterial blood pressure)|go:"GO:0003214"(cardiac left ventricle morphogenesis)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007212"(dopamine receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007568"(aging)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010905"(negative regulation of UDP-glucose catabolic process)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016477"(cell migration)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0036016"(cellular response to interleukin-3)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044027"(hypermethylation of CpG island)|go:"GO:0045719"(negative regulation of glycogen biosynthetic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0048156"(tau protein binding)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071879"(positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097440"(apical dendrite)|go:"GO:0098794"(postsynapse)|go:"GO:0106071"(positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1904227"(negative regulation of glycogen synthase activity, transferring glucose-1-phosphate)|go:"GO:1990635"(proximal dendrite)|go:"GO:2000077"(negative regulation of type B pancreatic cell development)|go:"GO:2000171"(negative regulation of dendrite development)|go:"GO:2000466"("negative regulation of glycogen (starch) synthase activity")|go:"GO:2000467"("positive regulation of glycogen (starch) synthase activity")|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR039192|mint:P49840|rcsb pdb:2DFM|reactome:R-HSA-198323|go:"GO:1901030"(positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|reactome:R-HSA-381038|reactome:R-HSA-5674400|reactome:R-HSA-9635465|reactome:R-HSA-9682706|reactome:R-HSA-9694686|refseq:NP_063937.2|uniprotkb:P49840(identity)|entrezgene/locuslink:2931(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:CTNNFDhWycUTAOEW/KD2UXu0U7Y9606 intact-crc:4167E0016E2251AA|rigid:FCirhlNcS2O93Jpq4kb812s1oy0 false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:P49840 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-1044067|uniprotkb:O14959|ensembl:ENSP00000222330|ensembl:ENSP00000412663 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:gsk3a_human(display_long)|uniprotkb:GSK3A(gene name)|psi-mi:GSK3A(display_short)|uniprotkb:Serine/threonine-protein kinase GSK3A(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090451|imex:IM-21827-151 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) ensembl:ENSG00000105723(gene)|ensembl:ENST00000222330(transcript)|ensembl:ENST00000453535(transcript)|go:"GO:0003073"(regulation of systemic arterial blood pressure)|go:"GO:0003214"(cardiac left ventricle morphogenesis)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007212"(dopamine receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007568"(aging)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010905"(negative regulation of UDP-glucose catabolic process)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016477"(cell migration)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0036016"(cellular response to interleukin-3)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044027"(hypermethylation of CpG island)|go:"GO:0045719"(negative regulation of glycogen biosynthetic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0048156"(tau protein binding)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071879"(positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097440"(apical dendrite)|go:"GO:0098794"(postsynapse)|go:"GO:0106071"(positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1904227"(negative regulation of glycogen synthase activity, transferring glucose-1-phosphate)|go:"GO:1990635"(proximal dendrite)|go:"GO:2000077"(negative regulation of type B pancreatic cell development)|go:"GO:2000171"(negative regulation of dendrite development)|go:"GO:2000466"("negative regulation of glycogen (starch) synthase activity")|go:"GO:2000467"("positive regulation of glycogen (starch) synthase activity")|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR039192|mint:P49840|rcsb pdb:2DFM|reactome:R-HSA-198323|go:"GO:1901030"(positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|reactome:R-HSA-381038|reactome:R-HSA-5674400|reactome:R-HSA-9635465|reactome:R-HSA-9682706|reactome:R-HSA-9694686|refseq:NP_063937.2|uniprotkb:P49840(identity)|ddbj/embl/genbank:BC027984(identity)|entrezgene/locuslink:2931(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:CTNNFDhWycUTAOEW/KD2UXu0U7Y9606 intact-crc:16D370C0A61F8F09|rigid:FCirhlNcS2O93Jpq4kb812s1oy0 false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50591 uniprotkb:Q8IUH5 intact:EBI-495373|ensembl:ENSP00000241261|uniprotkb:A1Y9B3 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:tnf10_human(display_long)|uniprotkb:TNF-related apoptosis-inducing ligand(gene name synonym)|uniprotkb:Apo-2 ligand(gene name synonym)|uniprotkb:TNFSF10(gene name)|psi-mi:TNFSF10(display_short)|uniprotkb:APO2L(gene name synonym)|uniprotkb:TRAIL(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090482|imex:IM-21827-153 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000241261(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|ensembl:ENSG00000121858(gene)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0032868"(response to insulin)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045569"(TRAIL binding)|go:"GO:0070062"(extracellular exosome)|refseq:NP_003801.1|refseq:NP_001177871.1|dip:DIP-6230N|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR017355(Tumour necrosis factor ligand superfamily member, 10/11)|interpro:IPR021184|rcsb pdb:1D0G|rcsb pdb:1D2Q|rcsb pdb:1D4V|rcsb pdb:1DG6|rcsb pdb:1DU3|rcsb pdb:4N90|rcsb pdb:5CIR|reactome:R-HSA-140534|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-69416|reactome:R-HSA-75158|uniprotkb:P50591(identity)|ddbj/embl/genbank:BC032722(identity)|entrezgene/locuslink:8743(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:hnOC/z7IWh8JRE86qlqUdVvNDUM9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:B140AFBF2DBC9B24|rigid:j+vTQ7EeByVsG8I+bYbf0JTyA+w false - sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P51674 uniprotkb:Q8IUH5 intact:EBI-7187133|ensembl:ENSP00000280187|ensembl:ENSP00000377268|intact:UNK-5379643|uniprotkb:Q92602|uniprotkb:E9PHI5|uniprotkb:B7Z642 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:gpm6a_human(display_long)|uniprotkb:GPM6A(gene name)|psi-mi:GPM6A(display_short)|uniprotkb:M6A(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090514|imex:IM-21827-155 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000150625(gene)|ensembl:ENST00000280187(transcript)|ensembl:ENST00000393658(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003407"(neural retina development)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007416"(synapse assembly)|go:"GO:0009617"(response to bacterium)|go:"GO:0030175"(filopodium)|go:"GO:0031175"(neuron projection development)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044295"(axonal growth cone)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR001614(Myelin proteolipid protein PLP)|interpro:IPR018237|refseq:NP_001248377.1|refseq:NP_963885.1|refseq:NP_005268.1|refseq:NP_963886.1|ddbj/embl/genbank:BC022508(identity)|entrezgene/locuslink:2823(identity)|uniprotkb:P51674(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) comment:mint|comment:homomint - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:6h/p/+l8WRhJ9HsGcbxleQuDtSo9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:3442D5D3EA7315BB|rigid:LqEIwgfaRcyLZlpgZ3CzWDM5ChA false - sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:P52756 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-714003|uniprotkb:Q93021|uniprotkb:Q9BU14|uniprotkb:Q9UKY8|uniprotkb:Q9UL24|ensembl:ENSP00000343054|uniprotkb:B2RA45|uniprotkb:B4DM16|uniprotkb:B4DMF9|uniprotkb:B4DZ63|uniprotkb:Q9HDA6|intact:EBI-16431417 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:rbm5_human(display_long)|uniprotkb:RNA-binding motif protein 5(gene name synonym)|uniprotkb:Putative tumor suppressor LUCA15(gene name synonym)|uniprotkb:Protein G15(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-9(gene name synonym)|uniprotkb:RBM5(gene name)|psi-mi:RBM5(display_short)|uniprotkb:H37(orf name)|uniprotkb:LUCA15(orf name) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090530|imex:IM-21827-156 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) ensembl:ENSG00000003756(gene)|ensembl:ENST00000347869(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR033094|interpro:IPR034991|interpro:IPR034993|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006396"(RNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000467(D111/G-patch)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036443|interpro:IPR041591|mint:P52756|rcsb pdb:2LK0|rcsb pdb:2LK1|rcsb pdb:2LKZ|rcsb pdb:5MF9|rcsb pdb:5MFY|reactome:R-HSA-72163|refseq:NP_005769.1|refseq:XP_016860992.1|dip:DIP-47277N|uniprotkb:P52756(identity)|entrezgene/locuslink:10181(identity)|ddbj/embl/genbank:BC002957(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:LsPTpaKrGY2xtpYofHbFVXjSi/A9606 intact-crc:F11B9A4FF5BFB072|rigid:jLtsHQuY8xO2ZdCv6YhvY/ihG+8 false sufficient binding region:64-487("MI:0442") sufficient binding region:1-546("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50995 uniprotkb:Q8IUH5 intact:EBI-715243|ensembl:ENSP00000361305|ensembl:ENSP00000398610|ensembl:ENSP00000404412|uniprotkb:B4DVE7|intact:EBI-10981770 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:anx11_human(display_long)|uniprotkb:Annexin-11(gene name synonym)|uniprotkb:Annexin XI(gene name synonym)|uniprotkb:Calcyclin-associated annexin 50(gene name synonym)|uniprotkb:56 kDa autoantigen(gene name synonym)|uniprotkb:ANXA11(gene name)|psi-mi:ANXA11(display_short)|uniprotkb:ANX11(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090498|imex:IM-21827-154 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000122359(gene)|ensembl:ENST00000372231(transcript)|ensembl:ENST00000422982(transcript)|ensembl:ENST00000438331(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006909"(phagocytosis)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016020"(membrane)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030496"(midbody)|go:"GO:0032506"(cytokinetic process)|go:"GO:0042470"(melanosome)|go:"GO:0042581"(specific granule)|go:"GO:0042582"(azurophil granule)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001464(Annexin)|interpro:IPR008157(Annexin, type XI, N-terminal)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|refseq:NP_001148.1|refseq:NP_665875.1|refseq:NP_665876.1|refseq:XP_011538038.1|refseq:NP_001265336.1|refseq:NP_001265337.1|refseq:NP_001265338.1|uniprotkb:P50995(identity)|entrezgene/locuslink:311(identity)|ddbj/embl/genbank:BC007564(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:6j7B4/J0DI0LZADQ5klJQoYf7289606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:4534E47678E626E7|rigid:/6nCt09twsQgXpu/dJN4maXevs0 false - sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P61086 uniprotkb:Q8IUH5 intact:EBI-473850|uniprotkb:A6NJC1|uniprotkb:O54806|uniprotkb:P27924|uniprotkb:Q16721|uniprotkb:Q9CVV9|uniprotkb:Q9Y2D3|uniprotkb:B2RDF8|uniprotkb:A8K5Y9|uniprotkb:C9JGP1|ensembl:ENSP00000261427 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:ube2k_human(display_long)|uniprotkb:HIP2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-25 kDa(gene name synonym)|uniprotkb:Ubiquitin-protein ligase(gene name synonym)|uniprotkb:Ubiquitin carrier protein(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2(gene name synonym)|uniprotkb:UBE2K(gene name)|psi-mi:UBE2K(display_short)|uniprotkb:LIG(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme K(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090549|imex:IM-21827-157 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001104582.1|refseq:NP_001104583.1|refseq:NP_005330.1|dip:DIP-32524N|ensembl:ENSG00000078140(gene)|ensembl:ENST00000261427(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032433"(filopodium tip)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|interpro:IPR042599|rcsb pdb:1YLA|rcsb pdb:2O25|rcsb pdb:3E46|rcsb pdb:3F92|rcsb pdb:3K9O|rcsb pdb:3K9P|rcsb pdb:5DFL|rcsb pdb:6IF1|rcsb pdb:6JB6|rcsb pdb:6JB7|reactome:R-HSA-8866652|reactome:R-HSA-936440|reactome:R-HSA-983168|uniprotkb:P61086(identity)|entrezgene/locuslink:3093(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:TTxSiXJ5fNdGUeuzYlPvDl8W7eg9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:3E6699A224167E9A|rigid:yCHrv99CEvnM/NBk2x+vUd/L3UY false - sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:P61224 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-358143|intact:EBI-1047928|uniprotkb:P09526|uniprotkb:Q6DCA1|uniprotkb:Q6LES0|uniprotkb:Q502X3|uniprotkb:Q5TZR4|uniprotkb:B2R5Z2|intact:EBI-11037134|uniprotkb:B4DQI8|uniprotkb:B4DW74|uniprotkb:B4DW94|ensembl:ENSP00000250559|ensembl:ENSP00000377085|ensembl:ENSP00000439966|ensembl:ENSP00000441275 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:rap1b_human(display_long)|uniprotkb:OK/SW-cl.11(orf name)|uniprotkb:RAP1B(gene name)|psi-mi:RAP1B(display_short)|uniprotkb:GTP-binding protein smg p21B(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090564|imex:IM-21827-158 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_001010942.1|refseq:NP_056461.1|dip:DIP-35407N|refseq:NP_001238846.1|refseq:NP_001238847.1|refseq:NP_001238850.1|refseq:NP_001238851.1|ensembl:ENSG00000127314(gene)|ensembl:ENST00000250559(transcript)|ensembl:ENST00000341355(transcript)|ensembl:ENST00000393436(transcript)|ensembl:ENST00000537460(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0016020"(membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0032486"(Rap protein signal transduction)|go:"GO:0033625"(positive regulation of integrin activation)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035690"|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045955"(negative regulation of calcium ion-dependent exocytosis)|go:"GO:0061028"(establishment of endothelial barrier)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0097211"(cellular response to gonadotropin-releasing hormone)|go:"GO:1901888"(regulation of cell junction assembly)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000301"(negative regulation of synaptic vesicle exocytosis)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|interpro:IPR038851|mint:P61224|rcsb pdb:3BRW|rcsb pdb:3CF6|rcsb pdb:4DXA|rcsb pdb:4HDO|rcsb pdb:4HDQ|rcsb pdb:4M8N|rcsb pdb:4MGI|rcsb pdb:4MGK|rcsb pdb:4MGY|rcsb pdb:4MGZ|rcsb pdb:4MH0|rcsb pdb:5KHO|rcsb pdb:6AXF|rcsb pdb:6BA6|rcsb pdb:6KYK|rcsb pdb:6OQ3|rcsb pdb:6OQ4|rcsb pdb:6UZK|rcsb pdb:7C7I|rcsb pdb:7C7J|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-392517|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8875555|reactome:R-HSA-8950505|reactome:R-HSA-9649948|reactome:R-HSA-9656223|uniprotkb:P61224(identity)|ddbj/embl/genbank:BC000176(identity)|entrezgene/locuslink:5908(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:CiuN7je+CaRH9QKDiR3vrzcJ87g9606 intact-crc:1C7D4AFC17D1E1CF|rigid:dfFY4iEiyCTQ/VMFMSwIINeo3V8 false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:P68104 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090580|imex:IM-21827-159 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1|uniprotkb:P68104(identity)|ddbj/embl/genbank:BC010735(identity)|entrezgene/locuslink:1915(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606 intact-crc:3ADAA349F42D4D88|rigid:BpLDa3GC7SU2Cicw3qWq0PqCzbA false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P68431 uniprotkb:Q8IUH5 intact:EBI-79722|ensembl:ENSP00000352252|ensembl:ENSP00000358160|ensembl:ENSP00000366999|ensembl:ENSP00000480826|ensembl:ENSP00000482271|ensembl:ENSP00000483283|ensembl:ENSP00000484095|ensembl:ENSP00000484638|ensembl:ENSP00000484658|ensembl:ENSP00000484841|ensembl:ENSP00000489282|intact:EBI-1560041|uniprotkb:A0PJT7|uniprotkb:P02295|uniprotkb:P02296|uniprotkb:P16106|uniprotkb:Q6ISV8|uniprotkb:Q6NWP8|uniprotkb:Q6NWP9|uniprotkb:Q6NXU4|uniprotkb:Q71DJ3|uniprotkb:Q93081|uniprotkb:A5PLR1 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:h31_human(display_long)|uniprotkb:H3FA(gene name synonym)|uniprotkb:H3FL(gene name synonym)|uniprotkb:H3FD(gene name synonym)|uniprotkb:H3FI(gene name synonym)|uniprotkb:H3FH(gene name synonym)|uniprotkb:H3FK(gene name synonym)|uniprotkb:H3FF(gene name synonym)|uniprotkb:H3FJ(gene name synonym)|uniprotkb:H3FB(gene name synonym)|uniprotkb:Histone H3/a(gene name synonym)|uniprotkb:Histone H3/b(gene name synonym)|uniprotkb:Histone H3/c(gene name synonym)|uniprotkb:Histone H3/d(gene name synonym)|uniprotkb:Histone H3/f(gene name synonym)|uniprotkb:Histone H3/h(gene name synonym)|uniprotkb:Histone H3/i(gene name synonym)|uniprotkb:Histone H3/j(gene name synonym)|uniprotkb:Histone H3/k(gene name synonym)|uniprotkb:Histone H3/l(gene name synonym)|uniprotkb:H3C1(gene name)|psi-mi:H3C1(display_short)|uniprotkb:HIST1H3A(gene name synonym)|uniprotkb:H3C2(gene name)|psi-mi:H3C2(display_short)|uniprotkb:HIST1H3B(gene name synonym)|uniprotkb:H3C3(gene name)|psi-mi:H3C3(display_short)|uniprotkb:H3FC HIST1H3C(gene name synonym)|uniprotkb:H3C4(gene name)|psi-mi:H3C4(display_short)|uniprotkb:HIST1H3D(gene name synonym)|uniprotkb:H3C6(gene name)|psi-mi:H3C6(display_short)|uniprotkb:HIST1H3E(gene name synonym)|uniprotkb:H3C7(gene name)|psi-mi:H3C7(display_short)|uniprotkb:HIST1H3F(gene name synonym)|uniprotkb:H3C8(gene name)|psi-mi:H3C8(display_short)|uniprotkb:HIST1H3G(gene name synonym)|uniprotkb:H3C10(gene name)|psi-mi:H3C10(display_short)|uniprotkb:HIST1H3H(gene name synonym)|uniprotkb:H3C11(gene name)|psi-mi:H3C11(display_short)|uniprotkb:HIST1H3I(gene name synonym)|uniprotkb:H3C12(gene name)|psi-mi:H3C12(display_short)|uniprotkb:HIST1H3J(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090596|imex:IM-21827-160 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4TN7|rcsb pdb:4U68|rcsb pdb:4UP0|rcsb pdb:4UY4|rcsb pdb:4X3K|rcsb pdb:4Y6L|rcsb pdb:4YHP|rcsb pdb:4YHZ|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z0R|rcsb pdb:4Z2M|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:4QBS|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B31|rcsb pdb:5C11|rcsb pdb:5C13|rcsb pdb:5C3I|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5D6Y|rcsb pdb:5DAH|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5FFV|rcsb pdb:5GH9|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5H6Q|rcsb pdb:5H6R|rcsb pdb:5HJB|rcsb pdb:5HJC|rcsb pdb:5HJD|rcsb pdb:5HYN|rcsb pdb:5IQL|rcsb pdb:5J3V|rcsb pdb:5J9S|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5B2J|rcsb pdb:5JRG|rcsb pdb:5KJH|rcsb pdb:5KJI|rcsb pdb:5KKL|rcsb pdb:5LUG|rcsb pdb:5M5G|rcsb pdb:5MR8|rcsb pdb:5NNC|rcsb pdb:5OY3|rcsb pdb:5SVX|rcsb pdb:5SVY|rcsb pdb:5SZB|rcsb pdb:5SZC|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5T1G|rcsb pdb:5T1I|rcsb pdb:5T8R|rcsb pdb:5TBN|rcsb pdb:5TDR|rcsb pdb:5TDW|rcsb pdb:5U2J|rcsb pdb:5V21|rcsb pdb:5V22|rcsb pdb:5VA6|rcsb pdb:5VAB|rcsb pdb:5VGE|rcsb pdb:5VNB|rcsb pdb:5NND|rcsb pdb:5WLE|rcsb pdb:5WVO|rcsb pdb:5WXG|rcsb pdb:5WXH|rcsb pdb:5WYI|rcsb pdb:5X60|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5XFQ|rcsb pdb:5XFR|rcsb pdb:5XNV|rcsb pdb:5XTZ|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Y20|rcsb pdb:5Y2F|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:6AXJ|rcsb pdb:6AZE|rcsb pdb:6BHD|rcsb pdb:6BHE|rcsb pdb:6BHG|rcsb pdb:6BHH|rcsb pdb:6BHI|rcsb pdb:6D07|rcsb pdb:6D08|rcsb pdb:6E83|rcsb pdb:6E86|rcsb pdb:5WFC|rcsb pdb:6F6D|rcsb pdb:6HTS|rcsb pdb:6IEU|rcsb pdb:6IIS|rcsb pdb:6IIT|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6JXD|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6LS6|rcsb pdb:6LSD|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MIL|rcsb pdb:6MIM|rcsb pdb:6MIN|rcsb pdb:6MIO|rcsb pdb:6MIQ|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6HKT|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2H|rcsb pdb:6V2K|rcsb pdb:6V3N|rcsb pdb:6V41|rcsb pdb:6V92|rcsb pdb:6VIL|rcsb pdb:6WAV|rcsb pdb:6WW4|rcsb pdb:6YIF|rcsb pdb:6YIH|rcsb pdb:6YOV|rcsb pdb:7BWD|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:6R92|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7DBP|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7KLR|rcsb pdb:7LYC|reactome:R-HSA-1266695|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|ensembl:ENSG00000197153(gene)|ensembl:ENSG00000197409(gene)|ensembl:ENSG00000273983(gene)|ensembl:ENSG00000274750(gene)|ensembl:ENSG00000275379(gene)|ensembl:ENSG00000275714(gene)|ensembl:ENSG00000277775(gene)|ensembl:ENSG00000278828(gene)|ensembl:ENSG00000286522(gene)|ensembl:ENSG00000287080(gene)|ensembl:ENST00000356476(transcript)|ensembl:ENST00000359303(transcript)|ensembl:ENST00000369163(transcript)|ensembl:ENST00000612966(transcript)|ensembl:ENST00000613854(transcript)|ensembl:ENST00000614378(transcript)|ensembl:ENST00000614911(transcript)|ensembl:ENST00000616365(transcript)|ensembl:ENST00000618052(transcript)|ensembl:ENST00000621411(transcript)|ensembl:ENST00000634733(transcript)|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-3247509|reactome:R-HSA-9710421|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060968"(obsolete regulation of gene silencing)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|interpro:IPR009072(Histone-fold)|mint:P68431|rcsb pdb:1CS9|rcsb pdb:1CT6|rcsb pdb:1O9S|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|rcsb pdb:1Q3L|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|rcsb pdb:2B2T|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|rcsb pdb:2B2U|rcsb pdb:2B2V|rcsb pdb:2B2W|rcsb pdb:2C1J|rcsb pdb:2C1N|go:"GO:0016020"(membrane)|rcsb pdb:2CO0|rcsb pdb:2CV5|rcsb pdb:2FSA|rcsb pdb:2KWJ|rcsb pdb:2KWK|rcsb pdb:2L75|rcsb pdb:2LBM|rcsb pdb:2LGG|rcsb pdb:2M0O|reactome:R-HSA-983231|reactome:R-HSA-977225|rcsb pdb:2NDG|rcsb pdb:2OQ6|rcsb pdb:2OT7|rcsb pdb:2OX0|rcsb pdb:2RI7|rcsb pdb:2RR4|rcsb pdb:2UXN|rcsb pdb:2V85|rcsb pdb:2V89|rcsb pdb:2VNF|rcsb pdb:2VPG|rcsb pdb:2X0L|rcsb pdb:3A1B|rcsb pdb:2NDF|rcsb pdb:3AFA|rcsb pdb:3AVR|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3B95|rcsb pdb:3FDT|rcsb pdb:3KMT|rcsb pdb:3KQI|rcsb pdb:3LQI|rcsb pdb:3LQJ|rcsb pdb:3MP1|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O37|rcsb pdb:3QJ6|rcsb pdb:3RIG|rcsb pdb:3RIY|rcsb pdb:3SOU|rcsb pdb:3SOW|rcsb pdb:3U31|rcsb pdb:3U3D|rcsb pdb:3U4S|rcsb pdb:3U5N|rcsb pdb:3U5O|rcsb pdb:3AZK|rcsb pdb:3U5P|rcsb pdb:3UEE|rcsb pdb:3UEF|rcsb pdb:3UII|rcsb pdb:3UIK|rcsb pdb:3V43|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:3ZG6|rcsb pdb:3ZVY|rcsb pdb:4A0J|rcsb pdb:4A0N|rcsb pdb:4A7J|rcsb pdb:3UIG|rcsb pdb:4BD3|rcsb pdb:4C1Q|rcsb pdb:4F4U|rcsb pdb:4F56|rcsb pdb:4FWF|rcsb pdb:4HON|rcsb pdb:4I51|rcsb pdb:4L7X|rcsb pdb:4LK9|rcsb pdb:4LKA|rcsb pdb:4LLB|rcsb pdb:4LXL|rcsb pdb:4N4H|rcsb pdb:4QBQ|rcsb pdb:4QBR|refseq:NP_003520.1|refseq:NP_003521.2|refseq:NP_003522.1|refseq:NP_003523.1|refseq:NP_003524.1|refseq:NP_003525.1|refseq:NP_003526.1|refseq:NP_003527.1|refseq:NP_003528.1|refseq:NP_066298.1|dip:DIP-29371N|uniprotkb:P68431(identity)|entrezgene/locuslink:8357(identity)|ddbj/embl/genbank:BC007518(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:ood0OohxZHuhsWZtO7U7GMc+LwM9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:B707C6386A3D4DF9|rigid:KWzkRv6JSeC8Kmuk1+A1DOr6kbc false - sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q06265 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-347966|ensembl:ENSP00000243498|uniprotkb:Q12883|uniprotkb:Q86Y41|uniprotkb:Q86Y48|uniprotkb:Q4W5P5 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:exos9_human(display_long)|uniprotkb:EXOSC9(gene name)|psi-mi:EXOSC9(display_short)|uniprotkb:PMSCL1(gene name synonym)|uniprotkb:Exosome component 9(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 1(gene name synonym)|uniprotkb:Autoantigen PM/Scl 1(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 75 kDa(gene name synonym)|uniprotkb:P75 polymyositis-scleroderma overlap syndrome-associated autoantigen(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090631|imex:IM-21827-162 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006955"(immune response)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR033100|interpro:IPR036345|mint:Q06265|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|ensembl:ENSG00000123737(gene)|ensembl:ENST00000243498(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|refseq:NP_001029366.1|refseq:NP_005024.2|dip:DIP-31286N|uniprotkb:Q06265(identity)|ddbj/embl/genbank:NM_005033(identity)|entrezgene/locuslink:5393(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:COzGZISdlfGlht1FhyxPhzbV9hY9606 intact-crc:9613EF63A11E93A5|rigid:hSFXBQfFj8EFO/IL5Fcz6Z1nZrc false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q04695 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-297873|ensembl:ENSP00000308452|uniprotkb:A5Z1M9|uniprotkb:A5Z1N0|uniprotkb:A5Z1N1|uniprotkb:A5Z1N2|uniprotkb:A6NDV6|uniprotkb:A6NKQ2|uniprotkb:Q6IP98|uniprotkb:Q8N1P6 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:k1c17_human(display_long)|uniprotkb:KRT17(gene name)|psi-mi:KRT17(display_short)|uniprotkb:Cytokeratin-17(gene name synonym)|uniprotkb:39.1(gene name synonym)|uniprotkb:Keratin-17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090612|imex:IM-21827-161 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) ensembl:ENSG00000128422(gene)|ensembl:ENST00000311208(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031424"(keratinization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0051798"(positive regulation of hair follicle development)|go:"GO:0071944"(cell periphery)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:Q04695|reactome:R-HSA-6805567|reactome:R-HSA-6809371|refseq:NP_000413.1|dip:DIP-33093N|uniprotkb:Q04695(identity)|ddbj/embl/genbank:BC072018(identity)|entrezgene/locuslink:3872(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:cwKlvMqhQGUokThbIxgEkB6Wzxw9606 intact-crc:8CB489B2936CF1D7|rigid:CZyTl2vZZKaD7IAIWMdfRG7SQXE false sufficient binding region:64-487("MI:0442") sufficient binding region:109-432("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q08499-8 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9090666|ensembl:ENSP00000321739 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:q08499-8(display_long)|uniprotkb:DPDE3(gene name synonym)|uniprotkb:PDE43(gene name synonym)|uniprotkb:PDE4D6(isoform synonym)|uniprotkb:PDE4D(gene name)|psi-mi:PDE4D(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090670|imex:IM-21827-164 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) intact:EBI-1642831(isoform-parent)|uniprotkb:Q08499-8(isoform-parent)|ensembl:ENSG00000113448(gene)|ensembl:ENST00000317118(transcript)|uniprotkb:Q08499-8(identity)|entrezgene/locuslink:5144(identity)|ddbj/embl/genbank:BC036319(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:LuLHIM+zWL+8B9s//iZdfoQXOhw9606 intact-crc:2BCBA7A109219E1B|rigid:n7VWkue5xV7aVYANvAVOpSVWn8w false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q09161 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-464743|uniprotkb:Q59G76|uniprotkb:Q5T1V0|ensembl:ENSP00000364289|uniprotkb:B2R718|uniprotkb:Q5T7X2 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:ncbp1_human(display_long)|uniprotkb:NCBP1(gene name)|psi-mi:NCBP1(display_short)|uniprotkb:CBP80(gene name synonym)|uniprotkb:NCBP(gene name synonym)|uniprotkb:80 kDa nuclear cap-binding protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090686|imex:IM-21827-165 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:1905216"(positive regulation of RNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR015172(MIF4G-like, type 1)|interpro:IPR015174(MIF4G-like, type 2)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027159|mint:Q09161|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|go:"GO:0031047"(gene silencing by RNA)|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-167158|ensembl:ENSG00000136937(gene)|ensembl:ENST00000375147(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006406"(mRNA export from nucleus)|refseq:NP_002477.1|dip:DIP-33244N|uniprotkb:Q09161(identity)|ddbj/embl/genbank:BC001450(identity)|entrezgene/locuslink:4686(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:VpCpiIQQZAXyOpu4J7G2k6ilhxY9606 intact-crc:4025FBB743223249|rigid:X7uASibUS0bUS5iaVHKlqPvrx7k false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q10981 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9090702|uniprotkb:Q14338|uniprotkb:Q5D0G2|uniprotkb:Q0VAG5|ensembl:ENSP00000375748|ensembl:ENSP00000387498|ensembl:ENSP00000430227 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:fut2_human(display_long)|uniprotkb:"Alpha(1,2)FT 2"(gene name synonym)|uniprotkb:Fucosyltransferase 2(gene name synonym)|uniprotkb:"GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 2"(gene name synonym)|uniprotkb:SE2(gene name synonym)|uniprotkb:SEC2(gene name synonym)|uniprotkb:Secretor blood group alpha-2-fucosyltransferase(gene name synonym)|uniprotkb:Secretor factor(gene name synonym)|uniprotkb:FUT2(gene name)|psi-mi:FUT2(display_short)|uniprotkb:"Type 1 galactoside alpha-(1,2)-fucosyltransferase FUT2"(gene name synonym)|uniprotkb:"Type 2 galactoside alpha-(1,2)-fucosyltransferase FUT2"(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090709|imex:IM-21827-166 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_000502.4|refseq:NP_001091107.1|ensembl:ENSG00000176920(gene)|ensembl:ENST00000391876(transcript)|ensembl:ENST00000425340(transcript)|ensembl:ENST00000522966(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001936"(regulation of endothelial cell proliferation)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006664"(glycolipid metabolic process)|go:"GO:0008107"(galactoside 2-alpha-L-fucosyltransferase activity)|go:"GO:0008417"(fucosyltransferase activity)|go:"GO:0009312"(oligosaccharide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0031127"("alpha-(1,2)-fucosyltransferase activity")|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0036065"(fucosylation)|go:"GO:0042355"(L-fucose catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002516(Glycosyl transferase, family 11)|reactome:R-HSA-9033807|reactome:R-HSA-9037629|uniprotkb:Q10981(identity)|entrezgene/locuslink:2524(identity)|ddbj/embl/genbank:BC001899(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:8aMIam5CTUlDHirqHJmneEGSPiQ9606 intact-crc:0521695625BFA370|rigid:iyFAOi7w3X9lyft3cKn9IUfPbdg false sufficient binding region:64-487("MI:0442") sufficient binding region:1-153("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08379 uniprotkb:Q8IUH5 intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090647|imex:IM-21827-163 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|uniprotkb:Q08379(identity)|ddbj/embl/genbank:BC069268(identity)|entrezgene/locuslink:2801(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:5C61F9DAD61AC861|rigid:jUrGhSZ1tfwLFKP5a6r9EIHD9PM false sufficient binding region:13-1002("MI:0442") sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q13573 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-632715|uniprotkb:Q13483|uniprotkb:Q32N03|uniprotkb:Q5D0D6|uniprotkb:A8K8A9|ensembl:ENSP00000261531 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:snw1_human(display_long)|uniprotkb:Nuclear protein SkiP(gene name synonym)|uniprotkb:Ski-interacting protein(gene name synonym)|uniprotkb:Nuclear receptor coactivator NCoA-62(gene name synonym)|uniprotkb:SKIIP(gene name synonym)|uniprotkb:SKIP(gene name synonym)|uniprotkb:SNW1(gene name)|psi-mi:SNW1(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090760|imex:IM-21827-169 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_036377.1|ensembl:ENSG00000100603(gene)|ensembl:ENST00000261531(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005112"(Notch binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0014010"(Schwann cell proliferation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048385"(regulation of retinoic acid receptor signaling pathway)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0070564"(positive regulation of vitamin D receptor signaling pathway)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071300"(cellular response to retinoic acid)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|mint:Q13573|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z58|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7AAV|rcsb pdb:7ABF|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-1912408|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2173796|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-72163|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|dip:DIP-34800N|uniprotkb:Q13573(identity)|ddbj/embl/genbank:BC108903(identity)|entrezgene/locuslink:22938(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:DwdpE5FIS2KfI0GOFt9IbAvjm/Y9606 intact-crc:8F735D92EBAAB380|rigid:rumfr7FhmEPK4MvkeR5LejzsLiY false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q12874 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-1051880|uniprotkb:Q15460|uniprotkb:Q5VT87|uniprotkb:D3DPT5|ensembl:ENSP00000362110 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:sf3a3_human(display_long)|uniprotkb:Spliceosome-associated protein 61(gene name synonym)|uniprotkb:SF3a60(gene name synonym)|uniprotkb:SF3A3(gene name)|psi-mi:SF3A3(display_short)|uniprotkb:SAP61(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090728|imex:IM-21827-167 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_006793.1|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1903241"(U2-type prespliceosome assembly)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR021966|interpro:IPR024598|interpro:IPR031774|interpro:IPR031776|mint:Q12874|rcsb pdb:2DT7|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|go:"GO:0000389"(mRNA 3'-splice site recognition)|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|reactome:R-HSA-72163|rcsb pdb:6Y53|ensembl:ENSG00000183431(gene)|ensembl:ENST00000373019(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|dip:DIP-882N|uniprotkb:Q12874(identity)|entrezgene/locuslink:10946(identity)|ddbj/embl/genbank:BC002395(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:fNjNguUOXqApr46rOAEpTs2geqY9606 intact-crc:88E5BF497C5B6825|rigid:VeDYMGn4szGPqPDXF3dgdLelZps false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12893 uniprotkb:Q8IUH5 intact:EBI-8633987|ensembl:ENSP00000266025|uniprotkb:A2IDB7|uniprotkb:Q6IAY4|uniprotkb:Q9UIX3|uniprotkb:O14568|intact:MINT-8162103 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:tm115_human(display_long)|uniprotkb:TMEM115(gene name)|psi-mi:TMEM115(display_short)|uniprotkb:PL6(gene name synonym)|uniprotkb:Placental protein 6(gene name synonym)|uniprotkb:Protein PL6(gene name synonym)|uniprotkb:LUCA11.2(orf name) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090744|imex:IM-21827-168 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000126062(gene)|ensembl:ENST00000266025(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR013861(Protein of unknown function DUF1751, integral membrane, eukaryotic)|interpro:IPR035952|reactome:R-HSA-6807878|refseq:NP_008955.1|uniprotkb:Q12893(identity)|ddbj/embl/genbank:BC011948(identity)|entrezgene/locuslink:11070(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) comment:mint - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:uudMguOuayjmb2C1lyPkBSpSB9Y9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:02D7CC916AF42D1B|rigid:dMkfQuEYcqTlS/LpWlZdfTsBBjw false - sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15642-2 uniprotkb:Q8IUH5 intact:EBI-6550597|ensembl:ENSP00000320493 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:q15642-2(display_long)|uniprotkb:A(isoform synonym)|uniprotkb:W(isoform synonym)|uniprotkb:TRIP10(gene name)|psi-mi:TRIP10(display_short)|uniprotkb:CIP4(gene name synonym)|uniprotkb:STOT(gene name synonym)|uniprotkb:STP(gene name synonym)|uniprotkb:Protein Felic(gene name synonym)|uniprotkb:Salt tolerant protein(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 10(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090827|imex:IM-21827-173 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q15642-2(isoform-parent)|ensembl:ENSG00000125733(gene)|ensembl:ENST00000313285(transcript)|intact:EBI-739936(isoform-parent)|uniprotkb:Q15642-2(identity)|entrezgene/locuslink:9322(identity)|ddbj/embl/genbank:BC013002(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:FppLeIANQu5tcNbD11u+F0kSOBQ9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:4B217D2DC22D801E|rigid:3GzKwTjPiHeM8Eyx8wrSlIWv8sA false - sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q155Q3-2 uniprotkb:Q8IUH5 intact:EBI-9088722|ensembl:ENSP00000480808 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:q155q3-2(display_long)|uniprotkb:CCD1(gene name synonym)|uniprotkb:Coiled-coil protein DIX1(gene name synonym)|uniprotkb:DIX domain-containing protein 1(gene name synonym)|uniprotkb:KIAA1735(gene name synonym)|uniprotkb:s-DIXDC1(isoform synonym)|uniprotkb:DIXDC1(gene name)|psi-mi:DIXDC1(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090812|imex:IM-21827-172 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1104700(isoform-parent)|ensembl:ENSG00000150764(gene)|ensembl:ENST00000615255(transcript)|uniprotkb:Q155Q3-2(identity)|entrezgene/locuslink:85458(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) isoform-comment:Major isoform. Preferentially expressed in cardiac and skeletal muscles. Initiator Met-1 is removed. Contains a N-myristoyl glycine at position 2. - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:ABLpXbDQcnGM7cwKKz4X9yfLweI9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:CAB0F2CB87B94A7B|rigid:wLuJaXiFOz43qwSABu3l2UfQFfQ false - sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q15047-2 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9090795|ensembl:ENSP00000357958 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:q15047-2(display_long)|uniprotkb:SETDB1(gene name)|psi-mi:SETDB1(display_short)|uniprotkb:ERG-associated protein with SET domain(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 4(gene name synonym)|uniprotkb:KIAA0067(gene name synonym)|uniprotkb:KMT1E(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1E(gene name synonym)|uniprotkb:SET domain bifurcated 1(gene name synonym)|uniprotkb:ESET(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090792|imex:IM-21827-171 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) ensembl:ENSG00000143379(gene)|ensembl:ENST00000368962(transcript)|intact:EBI-79691(isoform-parent)|uniprotkb:Q15047-2(isoform-parent)|uniprotkb:Q15047-2(identity)|entrezgene/locuslink:9869(identity)|ddbj/embl/genbank:BC009362(identity) psi-mi:"MI:0469"(intact) - isoform-comment:No experimental confirmation available. figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:ZRDrtJCxo50PTBfNTskZ+rLRXZM9606 intact-crc:CDA4F50C46A40CE2|rigid:lzmjFmvOlV+D30xFkHhiZqBFEac false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14154 uniprotkb:Q8IUH5 intact:EBI-2805660|ensembl:ENSP00000194118|ensembl:ENSP00000396225|uniprotkb:Q969R4|uniprotkb:Q96EU9|intact:EBI-2831226 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:dele1_human(display_long)|uniprotkb:DELE1(gene name)|psi-mi:DELE1(display_short)|uniprotkb:DELE(gene name synonym)|uniprotkb:Death ligand signal enhancer(gene name synonym)|uniprotkb:KIAA0141(gene name synonym)|uniprotkb:DAP3-binding cell death enhancer 1, long form(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090776|imex:IM-21827-170 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000081791(gene)|ensembl:ENST00000194118(transcript)|ensembl:ENST00000432126(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0019901"(protein kinase binding)|refseq:NP_001136075.1|refseq:NP_055588.3|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0140467"(integrated stress response signaling)|go:"GO:0140468"(HRI-mediated signaling)|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|refseq:XP_005268604.1|refseq:XP_005268605.1|uniprotkb:Q14154(identity)|entrezgene/locuslink:9812(identity)|ddbj/embl/genbank:BC011926(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:UBQ+baEp+eubj9KvSTnUTdJLq9g9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:DD98E4AC5D6B6CBC|rigid:nUIWEDY6sviq0HMf4m1eQgtgDB0 false - sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q2NKX8 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-1042535|uniprotkb:Q8NCI1|uniprotkb:Q96H93|uniprotkb:Q9NXQ8|intact:EBI-2560904|ensembl:ENSP00000334675 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:erc6l_human(display_long)|uniprotkb:ERCC6L(gene name)|psi-mi:ERCC6L(display_short)|uniprotkb:PICH(gene name synonym)|uniprotkb:ATP-dependent helicase ERCC6-like(gene name synonym)|uniprotkb:PLK1-interacting checkpoint helicase(gene name synonym)|uniprotkb:Tumor antigen BJ-HCC-15(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090858|imex:IM-21827-175 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_060139.2|ensembl:ENSG00000186871(gene)|ensembl:ENST00000334463(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016020"(membrane)|go:"GO:0051301"(cell division)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR038718|rcsb pdb:5JNO|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|uniprotkb:Q2NKX8(identity)|entrezgene/locuslink:54821(identity)|ddbj/embl/genbank:BC008808(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:3HZtZq9pgDyQB+UcxtAQjHv7+7o9606 intact-crc:854961F787E6D85C|rigid:L3zGnX1PTfVI1cKm5KCqqosmg5A false sufficient binding region:64-487("MI:0442") sufficient binding region:832-1250("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q16537 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-968374|uniprotkb:B7ZAW5|uniprotkb:J3KQN6|ensembl:ENSP00000337641|uniprotkb:Q52LW4|uniprotkb:A4FU37|uniprotkb:B7ZKK8|intact:EBI-10962508|uniprotkb:B7ZKK9 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:2a5e_human(display_long)|uniprotkb:PPP2R5E(gene name)|psi-mi:PPP2R5E(display_short)|uniprotkb:PP2A B subunit isoform B'-epsilon(gene name synonym)|uniprotkb:PP2A B subunit isoform B56-epsilon(gene name synonym)|uniprotkb:PP2A B subunit isoform PR61-epsilon(gene name synonym)|uniprotkb:PP2A B subunit isoform R5-epsilon(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090843|imex:IM-21827-174 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) ensembl:ENSG00000154001(gene)|ensembl:ENST00000337537(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0072542"(protein phosphatase activator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR016024(Armadillo-type fold)|mint:Q16537|reactome:R-HSA-141444|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-9648025|interpro:IPR011989(Armadillo-like helical)|refseq:NP_006237.1|refseq:NP_001269108.1|refseq:NP_001269109.1|refseq:NP_001269110.1|refseq:NP_001269111.1|uniprotkb:Q16537(identity)|entrezgene/locuslink:5529(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:m6vjnzx9eg+HpXrI2KKBLPbObzA9606 intact-crc:39C268F67D200597|rigid:sYX2FZFmJX+/8NpuJ8ILxsDz1q8 false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5BJF6-2 uniprotkb:Q8IUH5 intact:EBI-9090919 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:q5bjf6-2(display_long)|uniprotkb:Cenexin(gene name synonym)|uniprotkb:Outer dense fiber of sperm tails protein 2(gene name synonym)|uniprotkb:ODF2(gene name)|psi-mi:ODF2(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090916|imex:IM-21827-178 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-8744243(isoform-parent)|uniprotkb:Q5BJF6-2(isoform-parent)|uniprotkb:Q5BJF6-2(identity)|ddbj/embl/genbank:BC010629(identity)|entrezgene/locuslink:4957(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) isoform-comment:No experimental confirmation available. - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:W1Sv2KNHU+wsog/VTetbeuxXPkE9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:7A303AE9E3084F1B|rigid:c51kz+Pj0MJB5R+3h16aTuBRD1M false - sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O15130 uniprotkb:Q8IUH5 intact:EBI-9090899|uniprotkb:Q3SXL4|ensembl:ENSP00000267017 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:npff_human(display_long)|uniprotkb:NPFF(gene name)|psi-mi:NPFF(display_short)|uniprotkb:FMRFamide-related peptides(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090896|imex:IM-21827-177 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003708.1|ensembl:ENSG00000139574(gene)|ensembl:ENST00000267017(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005184"(neuropeptide hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0030425"(dendrite)|go:"GO:0043204"(perikaryon)|go:"GO:0043679"(axon terminus)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0098794"(postsynapse)|interpro:IPR008065(FMRFamide-related peptide 2)|reactome:R-HSA-389397|reactome:R-HSA-416476|go:"GO:0005615"(extracellular space)|refseq:NP_001307225.1|uniprotkb:Q3SXL4(identity)|ddbj/embl/genbank:BC104234(identity)|entrezgene/locuslink:8620(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:DRK0NRnr+1kZ5RnKc20CAtqz4eU9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:0B3B75AC272F98F4|rigid:QcvOWy7cq0Fbea02om4OgETBSmY false - sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q3B7T1 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-2870947|uniprotkb:B2RC65|uniprotkb:Q8IZ74|uniprotkb:Q3KR40|uniprotkb:Q9Y3W4|uniprotkb:Q5VZQ4|uniprotkb:Q4G190|ensembl:ENSP00000349244 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:edrf1_human(display_long)|uniprotkb:EDRF1(gene name)|psi-mi:EDRF1(display_short)|uniprotkb:C10orf137(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090877|imex:IM-21827-176 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_001189367.1|refseq:NP_056423.2|ensembl:ENSG00000107938(gene)|ensembl:ENST00000356792(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|uniprotkb:Q3B7T1(identity)|entrezgene/locuslink:26098(identity)|ddbj/embl/genbank:BC016903(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:VauF5uK1BOHW5dUr9V1XCzY9EPo9606 intact-crc:F0FF8AA1D2ED5634|rigid:VFTTPL5GB1LQ35Ov8Gb3792y5OA false sufficient binding region:64-487("MI:0442") sufficient binding region:675-1238("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q5VTR2 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-2372238|uniprotkb:Q2TB34|uniprotkb:Q69YL5|uniprotkb:Q6P527|uniprotkb:Q8N3J4|uniprotkb:Q96JD3|uniprotkb:Q9H9Y7|uniprotkb:Q9HA51|uniprotkb:Q9NUR4|uniprotkb:Q9NWQ3|uniprotkb:Q9NX83|uniprotkb:A7MCT5|ensembl:ENSP00000373772 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:bre1a_human(display_long)|uniprotkb:RNF20(gene name)|psi-mi:RNF20(display_short)|uniprotkb:BRE1A(gene name synonym)|uniprotkb:RING finger protein 20(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BRE1A(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090975|imex:IM-21827-181 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:XP_011517164.1|refseq:NP_062538.5|dip:DIP-53411N|ensembl:ENSG00000155827(gene)|ensembl:ENST00000389120(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033503"(HULC complex)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013956(E3 ubiquitin ligase, BRE1)|interpro:IPR017907|mint:Q5VTR2|rcsb pdb:5TRB|reactome:R-HSA-8866654|reactome:R-HSA-9013422|uniprotkb:Q5VTR2(identity)|entrezgene/locuslink:56254(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:zscBhEtpu0D69sPn1wXsEGBIiOY9606 intact-crc:14319ED2BB9EACCC|rigid:/bJVeJ0FDLbibuVP6P0Uwo1fJ68 false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5TGY3 uniprotkb:Q8IUH5 intact:EBI-948813|ensembl:ENSP00000247087|ensembl:ENSP00000363123|ensembl:ENSP00000494394|ensembl:ENSP00000495072|ensembl:ENSP00000495665|ensembl:ENSP00000501218|uniprotkb:Q5TGY4|uniprotkb:Q6PJK1|uniprotkb:Q6ZUQ6|uniprotkb:Q99769|uniprotkb:Q9NUF5 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:ahdc1_human(display_long)|uniprotkb:AHDC1(gene name)|psi-mi:AHDC1(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090956|imex:IM-21827-180 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000126705(gene)|ensembl:ENST00000247087(transcript)|ensembl:ENST00000374011(transcript)|ensembl:ENST00000642245(transcript)|ensembl:ENST00000642416(transcript)|ensembl:ENST00000644989(transcript)|ensembl:ENST00000673934(transcript)|go:"GO:0003677"(DNA binding)|interpro:IPR032757|interpro:IPR039225|mint:Q5TGY3|refseq:NP_001025053.1|refseq:XP_011539557.1|refseq:XP_011539558.1|refseq:XP_011539559.1|refseq:XP_005245905.1|refseq:XP_005245906.1|refseq:XP_005245907.1|refseq:XP_005245908.1|refseq:XP_005245909.1|uniprotkb:Q5TGY3(identity)|entrezgene/locuslink:27245(identity)|ddbj/embl/genbank:BC014394(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:lYUJEAEhxO204mZnqOd4Vf6K/g89606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:38CB71A43ABDBADF|rigid:SdzTCo+SNcjb1qH0IPNGaA4igCk false sufficient binding region:1205-1603("MI:0442") sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5D0E6-2 uniprotkb:Q8IUH5 intact:EBI-9090939|ensembl:ENSP00000410623 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:q5d0e6-2(display_long)|uniprotkb:DALRD3(gene name)|psi-mi:DALRD3(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090936|imex:IM-21827-179 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2871865(isoform-parent)|uniprotkb:Q5D0E6-2(isoform-parent)|ensembl:ENSG00000178149(gene)|ensembl:ENST00000441576(transcript)|uniprotkb:Q5D0E6-2(identity)|ddbj/embl/genbank:BC054493(identity)|entrezgene/locuslink:55152(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:6QIr/mx68VVc9C3fYsEwD7/gSPI9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:8E8FB09CBF9E567B|rigid:l2HmZW7WG0BiP+vsMJIibXqIBKc false - sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6I9S2 uniprotkb:Q8IUH5 intact:EBI-711215 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:q6i9s2_human(display_long)|uniprotkb:SNW1(gene name)|psi-mi:SNW1(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091033|imex:IM-21827-184 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR017862|interpro:IPR004015(SKIP/SNW)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|uniprotkb:Q6I9S2(identity)|entrezgene/locuslink:22938(identity)|ddbj/embl/genbank:CR457433(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:wFXsOKrt6F0ZWvKl0aTKRrIzKTg9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:CBE2644E236F061D|rigid:icwNyCsSYCRrNqGS3BBjSQfNM2I false - sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q68CL5-3 uniprotkb:Q8IUH5 intact:EBI-9091010|ensembl:ENSP00000466973 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:q68cl5-3(display_long)|uniprotkb:C18orf10(gene name synonym)|uniprotkb:HMFN0601(orf name)|uniprotkb:L17(orf name)|uniprotkb:TPGS2(gene name)|psi-mi:TPGS2(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091014|imex:IM-21827-183 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-748091(isoform-parent)|ensembl:ENSG00000134779(gene)|ensembl:ENST00000589049(transcript)|uniprotkb:Q68CL5-3(isoform-parent)|uniprotkb:Q68CL5-3(identity)|ddbj/embl/genbank:BC022199(identity)|entrezgene/locuslink:25941(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:D/vJwObPeifwKrEiD9f/gvP+q/E9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:27F17B54E2020C63|rigid:6LKzLMCpL2u9yWVJZog/8cnx7RY false sufficient binding region:61-227("MI:0442") sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q5W5X9-3 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9090990|ensembl:ENSP00000262074|ensembl:ENSP00000433162 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:q5w5x9-3(display_long)|uniprotkb:Cervical cancer proto-oncogene 8 protein(gene name synonym)|uniprotkb:HCC8(orf name)|uniprotkb:TTC23(gene name)|psi-mi:TTC23(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9090994|imex:IM-21827-182 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) intact:EBI-6447954(isoform-parent)|ensembl:ENSG00000103852(gene)|ensembl:ENST00000262074(transcript)|ensembl:ENST00000459771(transcript)|uniprotkb:Q5W5X9-3(isoform-parent)|uniprotkb:Q5W5X9-3(identity)|ddbj/embl/genbank:BC015728(identity)|entrezgene/locuslink:64927(identity) psi-mi:"MI:0469"(intact) - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. No experimental confirmation available. figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:M8gs/nlObbIu45M+eKJxQsXjTRE9606 intact-crc:0B01B33BC5B38264|rigid:KQVIOh3EgKii60sWYUK9vyEGG18 false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7RTV0 uniprotkb:Q8IUH5 intact:EBI-2555365|uniprotkb:Q9UH06|ensembl:ENSP00000216252 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:phf5a_human(display_long)|uniprotkb:Splicing factor 3B-associated 14 kDa protein(gene name synonym)|uniprotkb:PHF5A(gene name)|psi-mi:PHF5A(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091093|imex:IM-21827-187 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116147.1|ensembl:ENSG00000100410(gene)|ensembl:ENST00000216252(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR005345(PHF5-like)|mint:Q7RTV0|rcsb pdb:5IFE|rcsb pdb:5O9Z|rcsb pdb:5SYB|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:5ZYA|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6EN4|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|go:"GO:0048863"(stem cell differentiation)|uniprotkb:Q7RTV0(identity)|ddbj/embl/genbank:BC007321(identity)|entrezgene/locuslink:84844(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:TrngLk+KyJ+qRs8HGvH1LZH2Tsg9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:3BB9C7804873094D|rigid:lGGxBRtoYlpwwWca+HqjPm7pHFA false - sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6PCB5 uniprotkb:Q8IUH5 intact:EBI-9091072|uniprotkb:Q6ZVI9|uniprotkb:Q6ZS58|uniprotkb:Q86X48|uniprotkb:C9K0P1|ensembl:ENSP00000334040 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:rsbnl_human(display_long)|uniprotkb:Round spermatid basic protein 1-like protein(gene name synonym)|uniprotkb:RSBN1L(gene name)|psi-mi:RSBN1L(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091069|imex:IM-21827-186 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_940869.2|ensembl:ENSG00000187257(gene)|ensembl:ENST00000334955(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|interpro:IPR026306|uniprotkb:Q6PCB5(identity)|ddbj/embl/genbank:BC059402(identity)|entrezgene/locuslink:222194(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:r4BxnaLQPQ94s8brbdpiEVePieU9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:903E0F7216E004C2|rigid:SqDoD7pakqOF06bQuCu4brI/+88 false - sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6P4D5-2 uniprotkb:Q8IUH5 intact:EBI-9091052|ensembl:ENSP00000359821 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:q6p4d5-2(display_long)|uniprotkb:FAM122C(gene name synonym)|uniprotkb:PABIR3(gene name)|psi-mi:PABIR3(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091049|imex:IM-21827-185 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-9116315(isoform-parent)|ensembl:ENSG00000156500(gene)|ensembl:ENST00000370785(transcript)|uniprotkb:Q6P4D5-2(isoform-parent)|uniprotkb:Q6P4D5-2(identity)|ddbj/embl/genbank:BC017868(identity)|entrezgene/locuslink:159091(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) isoform-comment:No experimental confirmation available. - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:ofAjNmhmoQcs7DHFXoH0YTxeQRk9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:C5FFBEE6F5356661|rigid:ufXwnR5tXXdjwfwOxQD9fou1iLs false - sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7Z698 uniprotkb:Q8IUH5 intact:EBI-7082156|ensembl:ENSP00000348753|uniprotkb:A1L3V4|uniprotkb:B7Z5K7|intact:MINT-8020116|uniprotkb:Q2NKX6|uniprotkb:E9PEP0|uniprotkb:D6W5F7 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:spre2_human(display_long)|uniprotkb:SPRED2(gene name)|psi-mi:SPRED2(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091129|imex:IM-21827-189 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000198369(gene)|ensembl:ENST00000356388(transcript)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0005173"(stem cell factor receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:1902747"(negative regulation of lens fiber cell differentiation)|interpro:IPR000697(EVH1)|interpro:IPR007875(Sprouty)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023337|interpro:IPR041937|rcsb pdb:2JP2|reactome:R-HSA-5658442|reactome:R-HSA-5658623|reactome:R-HSA-6802953|refseq:NP_861449.2|refseq:NP_001121682.1|uniprotkb:Q7Z698(identity)|ddbj/embl/genbank:BC130292(identity)|entrezgene/locuslink:200734(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) comment:mint - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:Ao93NebBS40A8fFJk5b2ttbat0I9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:E40431B0A365183B|rigid:40vtx39wrol3pP7yYIACxFQTNM4 false - sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q8NFA0 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-2511075|ensembl:ENSP00000300896|intact:EBI-9091112|uniprotkb:Q7Z5T3|uniprotkb:Q9Y591|uniprotkb:Q9BX85 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:ubp32_human(display_long)|uniprotkb:USP32(gene name)|psi-mi:USP32(display_short)|uniprotkb:USP10(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 32(gene name synonym)|uniprotkb:Deubiquitinating enzyme 32(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-60(gene name synonym)|uniprotkb:Ubiquitin thioesterase 32(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091109|imex:IM-21827-188 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) ensembl:ENSG00000170832(gene)|ensembl:ENST00000300896(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016579"(protein deubiquitination)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR018200|interpro:IPR018247|interpro:IPR028889|interpro:IPR035927|interpro:IPR038765|interpro:IPR011992(EF-Hand type)|refseq:NP_115971.2|dip:DIP-53613N|uniprotkb:Q7Z5T3(identity)|ddbj/embl/genbank:BC054344(identity)|entrezgene/locuslink:84669(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:DOnkgvUHy/ldOL9DCSP8PJppAY09606 intact-crc:695F5C7A0F8EA06C|rigid:l4POG5nLRhAIEVTx5SD6NNBg4P0 false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q8IY31-3 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9091197|ensembl:ENSP00000350570 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:q8iy31-3(display_long)|uniprotkb:IFT20(gene name)|psi-mi:IFT20(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091201|imex:IM-21827-193 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) intact:EBI-744203(isoform-parent)|ensembl:ENSG00000109083(gene)|ensembl:ENST00000357896(transcript)|uniprotkb:Q8IY31-3(isoform-parent)|uniprotkb:Q8IY31-3(identity)|ddbj/embl/genbank:BC002640(identity)|entrezgene/locuslink:90410(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:pzW3oitgrBMPes/7NtSEKjfiDKU9606 intact-crc:0FC0EA4E607F406F|rigid:OXzn8w+g1rgEO/GCC1Jnf4s0R6g false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q8IUH5 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091181|imex:IM-21827-192 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|ddbj/embl/genbank:BC050324(identity)|entrezgene/locuslink:23390(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:FC252F7BCEDACF75|rigid:3F96lWb4skN4/qdb2khWY9O/paQ false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q8IUH5 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091163|imex:IM-21827-191 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|entrezgene/locuslink:23390(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:79355E7049722F31|rigid:3F96lWb4skN4/qdb2khWY9O/paQ false sufficient binding region:64-487("MI:0442") sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q8IUH5 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091145|imex:IM-21827-190 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|entrezgene/locuslink:23390(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:7093CC68075EC97A|rigid:3F96lWb4skN4/qdb2khWY9O/paQ false sufficient binding region:1-257("MI:0442") sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NCF5 uniprotkb:Q8IUH5 intact:EBI-5460702|uniprotkb:B7Z4G5|uniprotkb:Q66K34|uniprotkb:Q6NVK1|uniprotkb:Q8NFR2|uniprotkb:Q96ST9|ensembl:ENSP00000324792 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:nf2ip_human(display_long)|uniprotkb:Nuclear factor of activated T-cells, cytoplasmic 2-interacting protein(gene name synonym)|uniprotkb:NFATC2IP(gene name)|psi-mi:NFATC2IP(display_short)|uniprotkb:NIP45(gene name synonym)|uniprotkb:45 kDa NF-AT-interacting protein(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091253|imex:IM-21827-196 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116204.3|ensembl:ENSG00000176953(gene)|ensembl:ENST00000320805(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|mint:Q8NCF5|rcsb pdb:2JXX|rcsb pdb:2L76|rcsb pdb:3RD2|uniprotkb:Q8NCF5(identity)|ddbj/embl/genbank:BC018311(identity)|entrezgene/locuslink:84901(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:di/J7gYo8yHHPDe9APFBR7w2Rwc9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:226D229C4760B03C|rigid:lTWdRC7esU5Ku0CJFXCbRkVWXVo false sufficient binding region:282-419("MI:0442") sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IZU1 uniprotkb:Q8IUH5 intact:EBI-8468186|intact:MINT-8417663|uniprotkb:B7ZLH5|uniprotkb:Q2M2D1|ensembl:ENSP00000370391|ensembl:ENSP00000440163 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:fam9a_human(display_long)|uniprotkb:FAM9A(gene name)|psi-mi:FAM9A(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091237|imex:IM-21827-195 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_777611.1|refseq:NP_001164657.1|ensembl:ENSG00000183304(gene)|ensembl:ENST00000381003(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0007286"(spermatid development)|go:"GO:0051321"(meiotic cell cycle)|mint:Q8IZU1|ensembl:ENST00000543214(transcript)|uniprotkb:Q8IZU1(identity)|entrezgene/locuslink:171482(identity)|ddbj/embl/genbank:BC113449(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) comment:mint|comment:homomint - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:2LlKKs3tvntm/ZPF5v5U1g3QIEg9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:0352B9573D533A26|rigid:xVnjazZYM0qTIjHLfYF4/eFlqlQ false - sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q7Z5R6 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-2818084|intact:EBI-9091217|uniprotkb:Q8IYL7|uniprotkb:Q8IWS8|uniprotkb:Q8IZZ7|ensembl:ENSP00000365411 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:ab1ip_human(display_long)|uniprotkb:APBB1IP(gene name)|psi-mi:APBB1IP(display_short)|uniprotkb:PREL1(gene name synonym)|uniprotkb:RARP1(gene name synonym)|uniprotkb:RIAM(gene name synonym)|uniprotkb:APBB1-interacting protein 1(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 1(gene name synonym)|uniprotkb:Proline-rich protein 73(gene name synonym)|uniprotkb:Rap1-GTP-interacting adapter molecule(gene name synonym)|uniprotkb:Retinoic acid-responsive proline-rich protein 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091221|imex:IM-21827-194 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_061916.3|refseq:XP_006717514.1|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-6802952|ensembl:ENSG00000077420(gene)|ensembl:ENST00000376236(transcript)|go:"GO:0002291"(T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0030027"(lamellipodium)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0045785"(positive regulation of cell adhesion)|interpro:IPR000159(Ras-association)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR039664|interpro:IPR039665|rcsb pdb:2MWN|rcsb pdb:3ZDL|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|ensembl:ENST00000356785|ensembl:ENSP00000349237|ensembl:ENSP00000365411|uniprotkb:Q8IYL7(identity)|ddbj/embl/genbank:BC035636(identity)|entrezgene/locuslink:54518(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:PLBPCQJk3g1jocBsOm6vYnsTRpU9606 intact-crc:728E43C96CCC0747|rigid:549I4UnyogsLVSvP/CELzOSRpuc false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8WUE3 uniprotkb:Q8IUH5 intact:EBI-9091312|ensembl:ENSP00000379437 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:q8wue3_human(display_long)|uniprotkb:hCG_15054(orf name)|uniprotkb:CCNE2(gene name)|psi-mi:CCNE2(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091309|imex:IM-21827-199 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000175305(gene)|ensembl:ENST00000396133(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR028858|interpro:IPR036915|interpro:IPR039361|uniprotkb:Q8WUE3(identity)|ddbj/embl/genbank:BC020729(identity)|entrezgene/locuslink:9134(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:tYf/XLEu/1nNLNtn+9CbmOXbCeM9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:E57F4B6880341A4F|rigid:EyFpOQtMg8dpumi1BSWBYxTBy+Y false - sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q8TBK9 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-1056327 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:q8tbk9_human(display_long)|uniprotkb:PTMA(gene name)|psi-mi:PTMA(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091293|imex:IM-21827-198 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) interpro:IPR004931(Prothymosin/parathymosin)|uniprotkb:Q8TBK9(identity)|ddbj/embl/genbank:BC022433(identity)|entrezgene/locuslink:5757(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:fau5bL7CZfQWQRXIniNmCY+5tVQ9606 intact-crc:4F5F520286C28420|rigid:fv0a9LB7vhaI+hdOn1tPm5eTmnQ false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NCR9 uniprotkb:Q8IUH5 intact:EBI-9091272|uniprotkb:Q6MZX8|ensembl:ENSP00000357660 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:clrn3_human(display_long)|uniprotkb:TMEM12(gene name synonym)|uniprotkb:Transmembrane protein 12(gene name synonym)|uniprotkb:USH3AL1(gene name synonym)|uniprotkb:Usher syndrome type-3A-like protein 1(gene name synonym)|uniprotkb:CLRN3(gene name)|psi-mi:CLRN3(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091277|imex:IM-21827-197 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_689524.1|ensembl:ENSG00000180745(gene)|ensembl:ENST00000368671(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR026748|uniprotkb:Q8NCR9(identity)|ddbj/embl/genbank:BC029478(identity)|entrezgene/locuslink:119467(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:O9r601h+xV3k5OlI7/0t03GnAts9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:35AD48BF0F043163|rigid:wuri/FJ7BtWoV3VU1+lLhiRDfW8 false - sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q969Y6 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9091364 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:q969y6_human(display_long)|uniprotkb:DLK1(gene name)|psi-mi:DLK1(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091368|imex:IM-21827-202 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0016021"(integral component of membrane)|uniprotkb:Q969Y6(identity)|entrezgene/locuslink:8788(identity)|ddbj/embl/genbank:BC007741(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:eyl2yGQCZ+OAMe/4Cha4mzev6X09606 intact-crc:DFF79135296022B0|rigid:spQ+jVeUeKeA1K20qVGAYplcUbU false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q969H4 uniprotkb:Q8IUH5 intact:EBI-741671|uniprotkb:O95381|uniprotkb:B1AMW9|ensembl:ENSP00000363371 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:cnkr1_human(display_long)|uniprotkb:CNK homolog protein 1(gene name synonym)|uniprotkb:Connector enhancer of KSR-like(gene name synonym)|uniprotkb:CNKSR1(gene name)|psi-mi:CNKSR1(display_short)|uniprotkb:CNK1(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091348|imex:IM-21827-201 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006305.2|refseq:NP_001284576.1|refseq:NP_001284577.1|ensembl:ENSG00000142675(gene)|ensembl:ENST00000374253(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0030674"(protein-macromolecule adaptor activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR017874|interpro:IPR036034|rcsb pdb:1WWV|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|uniprotkb:Q969H4(identity)|ddbj/embl/genbank:BC011604(identity)|entrezgene/locuslink:10256(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:zpcFPQYAHRWVvI9tOOu7uCwTgq09606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:F9E831806A8355E4|rigid:UQpbGkDGZfzMf4mekf35PW0nz/Q false - sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q93079 uniprotkb:Q8IUH5 intact:EBI-352469|uniprotkb:Q4VB74|uniprotkb:B2R541|ensembl:ENSP00000479169 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:h2b1h_human(display_long)|uniprotkb:H2BC9(gene name)|psi-mi:H2BC9(display_short)|uniprotkb:H2B-clustered histone 9(gene name synonym)|uniprotkb:H2BFJ(gene name synonym)|uniprotkb:HIST1H2BH(gene name synonym)|uniprotkb:Histone H2B.j(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091329|imex:IM-21827-200 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003515.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019899"(enzyme binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|ensembl:ENSG00000275713(gene)|ensembl:ENST00000619466(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0097677"(STAT family protein binding)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|uniprotkb:Q93079(identity)|ddbj/embl/genbank:BC096116(identity)|entrezgene/locuslink:8345(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:W+7KkrtV9xv7ELLxmJFnI4LQoME9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:532B4E4E1202091F|rigid:bVxrxb5DvPeRBrbyG8QfAwNYPDY false sufficient binding region:1-126("MI:0442") sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96CV9-2 uniprotkb:Q8IUH5 intact:EBI-9091423|ensembl:ENSP00000368027|ensembl:ENSP00000368040 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:q96cv9-2(display_long)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091427|imex:IM-21827-205 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-748974(isoform-parent)|ensembl:ENST00000378752(transcript)|ensembl:ENST00000378764(transcript)|ensembl:ENSG00000123240(gene)|uniprotkb:Q96CV9-2(isoform-parent)|uniprotkb:Q96CV9-2(identity)|ddbj/embl/genbank:BC032762(identity)|entrezgene/locuslink:10133(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) isoform-comment:No experimental confirmation available. - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2018/04/06 rogid:ygzEQkiDJwDAMUuFQuOWsSIqwAk9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:5AD3D55254F6A2D7|rigid:QuIOv7mSpi10Z/MutH7/mS51ahU false - sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q96CN5 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-2805176|ensembl:ENSP00000306760 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:lrc45_human(display_long)|uniprotkb:LRRC45(gene name)|psi-mi:LRRC45(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091407|imex:IM-21827-204 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) ensembl:ENSG00000169683(gene)|ensembl:ENST00000306688(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|refseq:NP_659436.1|dip:DIP-29482N|uniprotkb:Q96CN5(identity)|entrezgene/locuslink:201255(identity)|ddbj/embl/genbank:BC014109(identity) psi-mi:"MI:0469"(intact) - crc64:27F5D210721459FB figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:cuIAlpH4zLJ1La+TtOc2x4c2dMI9606 intact-crc:9198306EB02105EC|rigid:qzhc3F3gtDl3X+6ZXl5CPgLHHP4 false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q96CG8 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9091387|uniprotkb:G3V141|uniprotkb:Q8IX63|uniprotkb:Q6UW91|ensembl:ENSP00000330523 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:cthr1_human(display_long)|uniprotkb:UNQ762/PRO1550(orf name)|uniprotkb:CTHRC1(gene name)|psi-mi:CTHRC1(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091384|imex:IM-21827-203 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_001243028.1|refseq:NP_612464.1|go:"GO:0043932"(ossification involved in bone remodeling)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090177"(establishment of planar polarity involved in neural tube closure)|ensembl:ENSG00000164932(gene)|ensembl:ENST00000330295(transcript)|go:"GO:0005109"(frizzled binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0016477"(cell migration)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|uniprotkb:Q96CG8(identity)|ddbj/embl/genbank:BC014245(identity)|entrezgene/locuslink:115908(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:WXdU4n1esE49WfV4ENbejv93xLs9606 intact-crc:4C255CE8DE0F395E|rigid:Mk41vfdzjF89/tlriQciYih4rlU false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q96HT8 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-748896|uniprotkb:Q6NXT8|uniprotkb:Q9P0J5|uniprotkb:B2R6R0|ensembl:ENSP00000318154 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:mr1l1_human(display_long)|uniprotkb:PP784(orf name)|uniprotkb:MRFAP1L1(gene name)|psi-mi:MRFAP1L1(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091479|imex:IM-21827-208 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_982287.1|refseq:XP_005247989.1|ensembl:ENSG00000178988(gene)|ensembl:ENST00000320848(transcript)|go:"GO:0042802"(identical protein binding)|interpro:IPR029254|mint:Q96HT8|dip:DIP-29019N|uniprotkb:Q96HT8(identity)|entrezgene/locuslink:114932(identity)|ddbj/embl/genbank:BC008087(identity) psi-mi:"MI:0469"(intact) - caution:This sequence has been withdrawn from Uniprot.|crc64:6C914B0B4BEECAE5 figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:hb4enqSS7DeieOByDoLDkXkSlIk9606 intact-crc:A4583D415874FF38|rigid:L85HB/dFCq16wwUNOtcCeKSM0Ug false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96H12 uniprotkb:Q8IUH5 intact:EBI-8466227|uniprotkb:Q5T728|uniprotkb:Q5T726|uniprotkb:Q5T727|intact:MINT-7032147|uniprotkb:B2RC35|ensembl:ENSP00000378506|ensembl:ENSP00000480445|ensembl:ENSP00000480622 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:msd3_human(display_long)|uniprotkb:MSANTD3(gene name)|psi-mi:MSANTD3(display_short)|uniprotkb:C9orf30(gene name synonym)|uniprotkb:L8(orf name) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091463|imex:IM-21827-207 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001185735.1|refseq:NP_001185734.1|refseq:NP_542386.1|refseq:NP_001185736.1|ensembl:ENSG00000066697(gene)|ensembl:ENST00000395067(transcript)|ensembl:ENST00000613183(transcript)|ensembl:ENST00000622639(transcript)|interpro:IPR026709|interpro:IPR028002|mint:Q96H12|uniprotkb:Q96H12(identity)|entrezgene/locuslink:91283(identity)|ddbj/embl/genbank:BC008993(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) comment:mint|comment:homomint - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:JOWl9WQVA131ZH45W9BYNpdEAJU9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:6CC7CA635B198AC0|rigid:VG4YAUqNAjA+s/Z9McxbfDgiReE false - sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q96GN5-2 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9091443 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:q96gn5-2(display_long)|uniprotkb:HR1(gene name synonym)|uniprotkb:JPO2(gene name synonym)|uniprotkb:Protein JPO2(gene name synonym)|uniprotkb:R1(gene name synonym)|uniprotkb:Transcription factor RAM2(gene name synonym)|uniprotkb:Variant B(isoform synonym)|uniprotkb:CDCA7L(gene name)|psi-mi:CDCA7L(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091447|imex:IM-21827-206 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) intact:EBI-5278764(isoform-parent)|uniprotkb:Q96GN5-2(isoform-parent)|uniprotkb:Q96GN5-2(identity)|entrezgene/locuslink:8701(identity)|ddbj/embl/genbank:BC025242(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:wcrQtkogtBLIPTSe1iz4xoeshSY9606 intact-crc:DC4D346370E7C354|rigid:NsCPBJbnJI4aKJ3BUc2boz1yA/E false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96KP4 uniprotkb:Q8IUH5 intact:EBI-1190734|uniprotkb:Q9BQ94|uniprotkb:Q9NVB4|uniprotkb:Q8WY59|uniprotkb:B3KUG4|uniprotkb:V9HWE5|ensembl:ENSP00000325548|ensembl:ENSP00000462311 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:cndp2_human(display_long)|uniprotkb:CNDP dipeptidase 2(gene name synonym)|uniprotkb:Glutamate carboxypeptidase-like protein 1(gene name synonym)|uniprotkb:Peptidase A(gene name synonym)|uniprotkb:HEL-S-13(gene name synonym)|uniprotkb:CNDP2(gene name)|psi-mi:CNDP2(display_short)|uniprotkb:CN2(gene name synonym)|uniprotkb:CPGL(gene name synonym)|uniprotkb:PEPA(gene name synonym)|uniprotkb:Threonyl dipeptidase(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091534|imex:IM-21827-211 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001161971.1|refseq:NP_060705.2|refseq:XP_005266785.1|refseq:XP_006722566.1|refseq:XP_011524373.1|refseq:XP_011524374.1|ensembl:ENSG00000133313(gene)|ensembl:ENST00000324262(transcript)|ensembl:ENST00000579847(transcript)|go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008233"(peptidase activity)|go:"GO:0016805"(dipeptidase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070573"(metallodipeptidase activity)|go:"GO:0103046"(alanylglutamate dipeptidase activity)|interpro:IPR001261(ArgE/DapE/ACY1/CPG2/YscS, conserved site)|interpro:IPR002933(Peptidase M20)|interpro:IPR011650(Peptidase M20, dimerisation)|interpro:IPR017153(Glutathione degradosome, DUG1)|rcsb pdb:4RUH|reactome:R-HSA-174403|uniprotkb:Q96KP4(identity)|entrezgene/locuslink:55748(identity)|ddbj/embl/genbank:BC003176(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:qAepmR2WYMtTL3WyP7AZz39LhkM9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:5AF633E262AAAFC5|rigid:BVPwxtCQAyocCDM/OBRidVgSLvE false - sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96K21 uniprotkb:Q8IUH5 intact:EBI-6448240|intact:EBI-9054731|ensembl:ENSP00000347498|uniprotkb:B3KVB2|uniprotkb:H3BUF9|uniprotkb:Q8WU96|uniprotkb:C9JNF4|uniprotkb:Q86WC2 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:anchr_human(display_long)|uniprotkb:MLL partner containing FYVE domain(gene name synonym)|uniprotkb:MPFYVE(gene name synonym)|uniprotkb:ZFYVE19(gene name)|psi-mi:ZFYVE19(display_short)|uniprotkb:ANCHR(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 19(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091515|imex:IM-21827-210 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000166140(gene)|ensembl:ENST00000355341(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0009838"(abscission)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0044878"(mitotic cytokinesis checkpoint signaling)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0090543"(Flemming body)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR044553|refseq:NP_001070736.1|refseq:NP_001245349.1|refseq:NP_001245350.1|refseq:NP_116239.3|dip:DIP-60854N|uniprotkb:Q96K21(identity)|entrezgene/locuslink:84936(identity)|ddbj/embl/genbank:BC015738(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:xxzfUBHGO3Fuepfq3If+5/nw+4U9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:F3BF256049272E3C|rigid:uhf3mh6f5yTAIndZeUJOQabBCP8 false sufficient binding region:76-471("MI:0442") sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96JB2-2 uniprotkb:Q8IUH5 intact:EBI-9091495|ensembl:ENSP00000481332 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:q96jb2-2(display_long)|uniprotkb:Component of oligomeric Golgi complex 3(gene name synonym)|uniprotkb:SEC34(gene name synonym)|uniprotkb:Vesicle-docking protein SEC34 homolog(gene name synonym)|uniprotkb:p94(gene name synonym)|uniprotkb:COG3(gene name)|psi-mi:COG3(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091499|imex:IM-21827-209 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2807756(isoform-parent)|ensembl:ENSG00000136152(gene)|ensembl:ENST00000617493(transcript)|uniprotkb:Q96JB2-2(isoform-parent)|uniprotkb:Q96JB2-2(identity)|entrezgene/locuslink:83548(identity)|ddbj/embl/genbank:BC038953(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) isoform-comment:No experimental confirmation available. - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:8zR2mtzqXJrsabjGTKUfhdINNZE9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:C192FF885B0E5223|rigid:8zI24uJ2C8bH0APYZ5ICTccmZcE false - sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96MW7 uniprotkb:Q8IUH5 intact:EBI-9091586|uniprotkb:Q6PIF9|uniprotkb:Q6P4D2|ensembl:ENSP00000386186 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:tigd1_human(display_long)|uniprotkb:TIGD1(gene name)|psi-mi:TIGD1(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091592|imex:IM-21827-214 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_663748.1|dip:DIP-61581N|ensembl:ENSG00000221944(gene)|ensembl:ENST00000408957(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|interpro:IPR004875(CENP-B protein)|interpro:IPR006600(Centromere protein B, helix-turn-helix)|interpro:IPR007889(Helix-turn-helix, Psq)|interpro:IPR009057(Homeodomain-like)|interpro:IPR036397|uniprotkb:Q96MW7(identity)|ddbj/embl/genbank:BC063500(identity)|entrezgene/locuslink:200765(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:tqCmDv+EG6oT8f6QQfrNJKjMeGg9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:6F96DB8C756161FA|rigid:fBCwAITYCkOj+nAuaQrBfFHPj7U false sufficient binding region:23-591("MI:0442") sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q96M83 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-742872|uniprotkb:Q8IVQ0|uniprotkb:Q8NEQ0|uniprotkb:Q5VW55|uniprotkb:B0QZ71|uniprotkb:Q08AN7|uniprotkb:Q8N7T7|uniprotkb:Q9H943|ensembl:ENSP00000491655 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:ccdc7_human(display_long)|uniprotkb:CCDC7(gene name)|psi-mi:CCDC7(display_short)|uniprotkb:BIOT2(gene name synonym)|uniprotkb:Protein BIOT2(gene name synonym)|uniprotkb:C10orf68(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091570|imex:IM-21827-213 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_001021554.1|refseq:NP_659460.3|refseq:NP_001308044.1|refseq:XP_011517965.1|ensembl:ENSG00000216937(gene)|ensembl:ENST00000639629(transcript)|interpro:IPR029272|uniprotkb:Q96M83(identity)|ddbj/embl/genbank:BC022020(identity)|entrezgene/locuslink:221016(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2016/07/12 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:roMRrC2qcDDSMwM7szy68bHMvR09606 intact-crc:D7AAA1FDEBBCBE24|rigid:otVm2FUe8vhw0WIBmRHo5nt5m4Q false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96LX8 uniprotkb:Q8IUH5 intact:EBI-9091553|ensembl:ENSP00000301744 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:zn597_human(display_long)|uniprotkb:ZNF597(gene name)|psi-mi:ZNF597(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091550|imex:IM-21827-212 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_689670.1|ensembl:ENSG00000167981(gene)|ensembl:ENST00000301744(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|uniprotkb:Q96LX8(identity)|ddbj/embl/genbank:BC029899(identity)|entrezgene/locuslink:146434(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:wJU9gbrQDuar5o6bWN1LwUMcUAc9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:7EF71008A6624613|rigid:5HGqfIzdEy+msl3EpvIoh9p1ePA false - sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BSL1 uniprotkb:Q8IUH5 intact:EBI-749370|uniprotkb:O75500|uniprotkb:Q9UMW7|ensembl:ENSP00000360821 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:ubac1_human(display_long)|uniprotkb:UBADC1(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase subunit KPC2(gene name synonym)|uniprotkb:Kip1 ubiquitination-promoting complex protein 2(gene name synonym)|uniprotkb:Glialblastoma cell differentiation-related protein 1(gene name synonym)|uniprotkb:UBAC1(gene name)|psi-mi:UBAC1(display_short)|uniprotkb:GBDR1(gene name synonym)|uniprotkb:KPC2(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091627|imex:IM-21827-216 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057256.2|dip:DIP-47279N|ensembl:ENSG00000130560(gene)|ensembl:ENST00000371756(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0070062"(extracellular exosome)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR041926|interpro:IPR041927|mint:Q9BSL1|rcsb pdb:2DAI|reactome:R-HSA-983168|go:"GO:0005886"(plasma membrane)|uniprotkb:Q9BSL1(identity)|entrezgene/locuslink:10422(identity)|ddbj/embl/genbank:BC004967(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:xgBRjmUpQ2UGdiEu5KQSZVy7TrQ9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:96D699EF356FD725|rigid:/pG/v5HvcPKu+7ckrZ793Xs0xLA false - sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99828 uniprotkb:Q8IUH5 intact:EBI-372594|uniprotkb:B5BU40|uniprotkb:O00693|uniprotkb:O00735|uniprotkb:Q6IB49|uniprotkb:Q96J54|uniprotkb:Q99971|uniprotkb:H6WJF3|ensembl:ENSP00000333873 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:cib1_human(display_long)|uniprotkb:Calmyrin(gene name synonym)|uniprotkb:DNA-PKcs-interacting protein(gene name synonym)|uniprotkb:Kinase-interacting protein(gene name synonym)|uniprotkb:SNK-interacting protein 2-28(gene name synonym)|uniprotkb:CIB1(gene name)|psi-mi:CIB1(display_short)|uniprotkb:CIB(gene name synonym)|uniprotkb:KIP(gene name synonym)|uniprotkb:PRKDCIP(gene name synonym)|uniprotkb:Calcium- and integrin-binding protein(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091611|imex:IM-21827-215 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006375.2|go:"GO:0002931"(response to ischemia)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007113"(endomitotic cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007286"(spermatid development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008427"(calcium-dependent protein kinase inhibitor activity)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030220"(platelet formation)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031982"(vesicle)|go:"GO:0032433"(filopodium tip)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033630"(positive regulation of cell adhesion mediated by integrin)|go:"GO:0038163"(thrombopoietin-mediated signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043204"(perikaryon)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070886"(positive regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|ensembl:ENSG00000185043(gene)|ensembl:ENST00000328649(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0071944"(cell periphery)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000256"(positive regulation of male germ cell proliferation)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q99828|rcsb pdb:1DGU|rcsb pdb:1DGV|rcsb pdb:1XO5|rcsb pdb:1Y1A|rcsb pdb:2L4H|rcsb pdb:2L4I|rcsb pdb:6OCX|rcsb pdb:6OD0|rcsb pdb:2LM5|refseq:NP_001264693.1|dip:DIP-31260N|uniprotkb:Q99828(identity)|entrezgene/locuslink:10519(identity)|ddbj/embl/genbank:BC000846(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:6nPuuJSN/emL6jukTGtT2ab+jNU9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:1774E12A8F260DE8|rigid:J8IqufU+d+JY9D/tCs71igZnhEA false - sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q9BXY8 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-745073|uniprotkb:Q5JVV9|uniprotkb:B2R574|ensembl:ENSP00000361759|ensembl:ENSP00000361762|uniprotkb:D3DXA2|uniprotkb:F5H7H5 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:bex2_human(display_long)|uniprotkb:Brain-expressed X-linked protein 2(gene name synonym)|uniprotkb:BEX2(gene name)|psi-mi:BEX2(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091675|imex:IM-21827-219 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_001161872.1|refseq:NP_001161873.1|refseq:NP_116010.1|ensembl:ENSG00000133134(gene)|ensembl:ENST00000372674(transcript)|ensembl:ENST00000372677(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR007623(Brain expressed X-linked like protein)|interpro:IPR021156|refseq:NP_001161871.1|uniprotkb:Q9BXY8(identity)|entrezgene/locuslink:84707(identity)|ddbj/embl/genbank:BC015522(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:Ph15ZEtbP3i54mLfnXgxiEeCRbM9606 intact-crc:FC750AB13B525CE8|rigid:K+GgHMxlYEKUEnaKD5DQFNq13zQ false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q9BTA9 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-749118|intact:EBI-947208|uniprotkb:C9JBT9|uniprotkb:Q5JU75|uniprotkb:Q5JU77|uniprotkb:Q53EN9|uniprotkb:Q5VXK0|uniprotkb:Q5VXK2|uniprotkb:Q8TCK1|uniprotkb:Q96DP3|uniprotkb:Q96FW6|uniprotkb:Q96JI3|uniprotkb:A8K2A9|intact:EBI-1105304|uniprotkb:D3DRW5|uniprotkb:D3DRW6|uniprotkb:D3DRW7|ensembl:ENSP00000346986 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:wac_human(display_long)|uniprotkb:WAC(gene name)|psi-mi:WAC(display_short)|uniprotkb:KIAA1844(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091659|imex:IM-21827-218 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:XP_011517793.1|refseq:NP_057712.2|refseq:NP_567823.1|refseq:NP_567822.1|ensembl:ENSG00000095787(gene)|ensembl:ENST00000354911(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071894"(histone H2B conserved C-terminal lysine ubiquitination)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|interpro:IPR038867|reactome:R-HSA-8866654|go:"GO:0016607"(nuclear speck)|uniprotkb:Q9BTA9(identity)|ddbj/embl/genbank:BC004258(identity)|entrezgene/locuslink:51322(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:TuCxRb98Y5EGRbK1RRNMi/VnXV89606 intact-crc:644B22DB70AFB4F1|rigid:ykmwfEMD6P0Gq3sWBBKoOFd0Mdw false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BT49 uniprotkb:Q8IUH5 intact:EBI-741350|ensembl:ENSP00000215742|ensembl:ENSP00000382084|uniprotkb:B2RD97|uniprotkb:D3DX40 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:thap7_human(display_long)|uniprotkb:THAP7(gene name)|psi-mi:THAP7(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091643|imex:IM-21827-217 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001008695.1|refseq:NP_085050.2|ensembl:ENSG00000184436(gene)|ensembl:ENST00000215742(transcript)|ensembl:ENST00000399133(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016607"(nuclear speck)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0106153"(phosphorylated histone binding)|go:"GO:0140296"(general transcription initiation factor binding)|interpro:IPR006612(Zinc finger, C2CH-type)|interpro:IPR026519|uniprotkb:Q9BT49(identity)|ddbj/embl/genbank:BC004346(identity)|entrezgene/locuslink:80764(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:4efYWbkvlRsynamdao3y6gVxhtA9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:145486B9BFEEB4B0|rigid:lWM4g86MvqWCriiyOH7gEqdJ/5w false - sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q9H4A5 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-4403434|uniprotkb:B7Z6N3|uniprotkb:B1AN09|uniprotkb:Q9NVK0|ensembl:ENSP00000271732 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:glp3l_human(display_long)|uniprotkb:GOLPH3L(gene name)|psi-mi:GOLPH3L(display_short)|uniprotkb:GPP34R(gene name synonym)|uniprotkb:GPP34-related protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091733|imex:IM-21827-222 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_060648.2|ensembl:ENSG00000143457(gene)|ensembl:ENST00000271732(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007030"(Golgi organization)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|interpro:IPR008628(Golgi phosphoprotein 3)|interpro:IPR038261|mint:Q9H4A5|uniprotkb:Q9H4A5(identity)|entrezgene/locuslink:55204(identity)|ddbj/embl/genbank:BC013870(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:E+0Ru85nv0KoO/LW0kZLN1vpbFc9606 intact-crc:F2F6219C5DB68599|rigid:Lx0FrpCKgYYOgguNZ5BPrhF0esM false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q9H0V9 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9091707|uniprotkb:Q53S67|uniprotkb:Q8NBQ6|uniprotkb:D3DXH6|uniprotkb:Q63HN6|uniprotkb:Q53GV3|uniprotkb:Q9BQ14|uniprotkb:B4DSH3|ensembl:ENSP00000264963 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:lma2l_human(display_long)|uniprotkb:Lectin mannose-binding 2-like(gene name synonym)|uniprotkb:VIPL(gene name synonym)|uniprotkb:PSEC0028(orf name)|uniprotkb:UNQ368/PRO704(orf name)|uniprotkb:LMAN2L(gene name)|psi-mi:LMAN2L(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091717|imex:IM-21827-221 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_001135764.1|refseq:NP_110432.1|refseq:NP_001309279.1|refseq:NP_001309280.1|refseq:NP_001309283.1|refseq:NP_001309276.1|refseq:NP_001309275.1|ensembl:ENSG00000114988(gene)|ensembl:ENST00000264963(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005537"(mannose binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006457"(protein folding)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0046872"(metal ion binding)|interpro:IPR005052(Legume-like lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|reactome:R-HSA-204005|reactome:R-HSA-5694530|uniprotkb:Q9H0V9(identity)|entrezgene/locuslink:81562(identity)|ddbj/embl/genbank:BC067265(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:sXVInY7CJsVQIeO5FWJsDBWqQak9606 intact-crc:E944470254B0828C|rigid:wlTrMvoKee7BP7xsBWd3e+HZNpU false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q9BYN7 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9089622|uniprotkb:Q5JXM8|uniprotkb:B7ZM09|uniprotkb:B2RXE5|uniprotkb:Q96ST5|uniprotkb:A2RUF4|ensembl:ENSP00000364346 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:zn341_human(display_long)|uniprotkb:ZNF341(gene name)|psi-mi:ZNF341(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091691|imex:IM-21827-220 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_001269862.1|refseq:NP_001269864.1|refseq:NP_116208.3|ensembl:ENSG00000131061(gene)|ensembl:ENST00000375200(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|uniprotkb:Q9BYN7(identity)|entrezgene/locuslink:84905(identity)|ddbj/embl/genbank:BC132873(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:dEc17LamYWGrumF7ngc3Ayq4Q5E9606 intact-crc:52EC54A7EFEC96FD|rigid:KpU+DBjQL9o4VU+iGkyxZWvqrSY false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H6U6-6 uniprotkb:Q8IUH5 intact:EBI-9089698|ensembl:ENSP00000464825 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:q9h6u6-6(display_long)|uniprotkb:Breast carcinoma-amplified sequence 3(gene name synonym)|uniprotkb:GAOB1(gene name synonym)|uniprotkb:Maaab2(isoform synonym)|uniprotkb:BCAS3(gene name)|psi-mi:BCAS3(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091765|imex:IM-21827-224 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6083685(isoform-parent)|ensembl:ENSG00000141376(gene)|ensembl:ENST00000588874(transcript)|uniprotkb:Q9H6U6-6(identity)|ddbj/embl/genbank:BC001250(identity)|entrezgene/locuslink:54828(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:Me4sRk7FArlInTLgRmhTOzW9SG49606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:D28ACC9E6586C845|rigid:vd79z8dwUwKVVbF64puBbglP85k false sufficient binding region:295-684("MI:0442") sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H668 uniprotkb:Q8IUH5 intact:EBI-746930|uniprotkb:Q5TCZ0|uniprotkb:D3DR99|ensembl:ENSP00000224950|ensembl:ENSP00000358779 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:stn1_human(display_long)|uniprotkb:STN1(gene name)|psi-mi:STN1(display_short)|uniprotkb:OBFC1(gene name synonym)|uniprotkb:Oligonucleotide/oligosaccharide-binding fold-containing protein 1(gene name synonym)|uniprotkb:Suppressor of cdc thirteen homolog(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091749|imex:IM-21827-223 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006718039.1|refseq:NP_079204.2|ensembl:ENSG00000107960(gene)|ensembl:ENST00000224950(transcript)|ensembl:ENST00000369764(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001650"(fibrillar center)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016233"(telomere capping)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:1990879"(CST complex)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014647(Uncharacterised protein with OB-fold)|interpro:IPR015253(Region of unknown function DUF1879)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040260|interpro:IPR042082|rcsb pdb:4JOI|rcsb pdb:4JQF|rcsb pdb:6W6W|reactome:R-HSA-174411|reactome:R-HSA-174430|refseq:XP_016872158.1|refseq:XP_016872159.1|dip:DIP-59914N|uniprotkb:Q9H668(identity)|entrezgene/locuslink:79991(identity)|ddbj/embl/genbank:BC017400(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:bcmazDHRYRmgdk1waIzSspUjupY9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:16DEAC0C3294C569|rigid:fGrSBclXFJBp24kKs+Pja/ObdOQ false - sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q9NP61 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-2875816|ensembl:ENSP00000263245|uniprotkb:Q9Y4V4|uniprotkb:Q9NUP5|uniprotkb:Q9Y4V3|uniprotkb:Q9NT10|uniprotkb:Q9BSC6|uniprotkb:Q9H9J0|uniprotkb:E9PB03 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:arfg3_human(display_long)|uniprotkb:ARFGAP3(gene name)|psi-mi:ARFGAP3(display_short)|uniprotkb:ARFGAP1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091800|imex:IM-21827-226 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) ensembl:ENSG00000242247(gene)|ensembl:ENST00000263245(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0009306"(protein secretion)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0048205"(COPI coating of Golgi vesicle)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR037278|interpro:IPR038508|rcsb pdb:2CRW|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-9013148|reactome:R-HSA-9013408|go:"GO:0005096"(GTPase activator activity)|refseq:NP_001135765.1|refseq:NP_055385.3|uniprotkb:Q9NP61(identity)|ddbj/embl/genbank:BC005122(identity)|entrezgene/locuslink:26286(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:1868s5elsn/sX/f8if3lmbLxKxg9606 intact-crc:45FFFECC65907AC4|rigid:ZyzrmLJFEOOHi+THbM0Iaw5AiCw false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H9Z2 uniprotkb:Q8IUH5 intact:EBI-2462365|ensembl:ENSP00000254231|ensembl:ENSP00000363314 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:ln28a_human(display_long)|uniprotkb:LIN28A(gene name)|psi-mi:LIN28A(display_short)|uniprotkb:CSDD1(gene name synonym)|uniprotkb:LIN28(gene name synonym)|uniprotkb:ZCCHC1(gene name synonym)|uniprotkb:Zinc finger CCHC domain-containing protein 1(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091784|imex:IM-21827-225 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011540450.1|refseq:NP_078950.1|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0035198"(miRNA binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045686"(negative regulation of glial cell differentiation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071076"(RNA 3' uridylation)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:1901724"(positive regulation of cell proliferation involved in kidney development)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1905538"(polysome binding)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR036875|mint:Q9H9Z2|rcsb pdb:2CQF|rcsb pdb:2LI8|rcsb pdb:5UDZ|reactome:R-HSA-452723|ensembl:ENSG00000131914(gene)|ensembl:ENST00000254231(transcript)|ensembl:ENST00000326279(transcript)|go:"GO:0000932"(P-body)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010587"(miRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0031123"(RNA 3'-end processing)|uniprotkb:Q9H9Z2(identity)|entrezgene/locuslink:79727(identity)|ddbj/embl/genbank:BC028566(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:+74ZEfwOtT0fztME4RpHlyYIlww9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:89C6A3D4C6905611|rigid:RprhfcOmEK6qHANWKMGxv8CVq7s false - sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q9NWB7 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-725672|intact:EBI-1581177|uniprotkb:Q96DA9|ensembl:ENSP00000264538 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:ift57_human(display_long)|uniprotkb:IFT57(gene name)|psi-mi:IFT57(display_short)|uniprotkb:DERP8(gene name synonym)|uniprotkb:ESRRBL1(gene name synonym)|uniprotkb:HIPPI(gene name synonym)|uniprotkb:HIP1-interacting protein(gene name synonym)|uniprotkb:Estrogen-related receptor beta-like protein 1(gene name synonym)|uniprotkb:Dermal papilla-derived protein 8(gene name synonym)|uniprotkb:MHS4R2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091852|imex:IM-21827-229 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_060480.1|ensembl:ENSG00000114446(gene)|ensembl:ENST00000264538(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003677"(DNA binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0030992"(intraciliary transport particle B)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044292"(dendrite terminus)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0060972"(left/right pattern formation)|go:"GO:0097542"(ciliary tip)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR019530|reactome:R-HSA-5610787|reactome:R-HSA-5620924|uniprotkb:Q9NWB7(identity)|ddbj/embl/genbank:BC011899(identity)|entrezgene/locuslink:55081(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:dwediEVcY3c1oEqj6xTpaae4aTk9606 intact-crc:9FAE49F25B525E65|rigid:JAgXWozzF4FmAyXVvNNV+/c8I5E false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NSI2 uniprotkb:Q8IUH5 intact:EBI-5457304|ensembl:ENSP00000291634 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:slx9_human(display_long)|uniprotkb:SLX9(gene name)|psi-mi:SLX9(display_short)|uniprotkb:C21orf70(gene name synonym)|uniprotkb:FAM207A(gene name synonym)|uniprotkb:PRED56(orf name) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091836|imex:IM-21827-228 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001303912.1|refseq:NP_001303913.1|refseq:NP_001303914.1|refseq:NP_001303915.1|refseq:NP_001303917.1|refseq:NP_478070.1|ensembl:ENSG00000160256(gene)|ensembl:ENST00000291634(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005730"(nucleolus)|go:"GO:0030686"(90S preribosome)|go:"GO:0030688"(preribosome, small subunit precursor)|interpro:IPR028160|uniprotkb:Q9NSI2(identity)|ddbj/embl/genbank:BC009341(identity)|entrezgene/locuslink:85395(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:pCNahk8BsVfGLtrB/Y290fJCA5g9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:217D57ED01F6BC57|rigid:anlIPjkwcywK1dR49VT++yFi9PQ false - sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q9NPQ8-4 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9091816 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:q9npq8-4(display_long)|uniprotkb:Protein Ric-8A(gene name synonym)|uniprotkb:RIC8A(gene name)|psi-mi:RIC8A(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091820|imex:IM-21827-227 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) intact:EBI-717509(isoform-parent)|uniprotkb:Q9NPQ8-4(isoform-parent)|uniprotkb:Q9NPQ8-4(identity)|ddbj/embl/genbank:BC121808(identity)|entrezgene/locuslink:60626(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:a3j893jMJ2OrxJOciF5RMaXZoAs9606 intact-crc:0B6666630B884D4E|rigid:XMJv/YDzG1JsaGqXbHm3CXHbUGo false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q9UF11-4 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9089825|ensembl:ENSP00000227214|ensembl:ENSP00000442616 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:q9uf11-4(display_long)|uniprotkb:EVT1(gene name synonym)|uniprotkb:Evectin-1(gene name synonym)|uniprotkb:KPL1(gene name synonym)|uniprotkb:PH domain-containing protein in retina 1(gene name synonym)|uniprotkb:PHR1(gene name synonym)|uniprotkb:PHRET1(gene name synonym)|uniprotkb:Pleckstrin homology domain retinal protein 1(gene name synonym)|uniprotkb:PLEKHB1(gene name)|psi-mi:PLEKHB1(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091904|imex:IM-21827-232 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) intact:EBI-6447271(isoform-parent)|ensembl:ENSG00000021300(gene)|ensembl:ENST00000227214(transcript)|ensembl:ENST00000535129(transcript)|uniprotkb:Q9UF11-4(identity)|entrezgene/locuslink:58473(identity)|ddbj/embl/genbank:BC008075(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:5RmF2rJLHJT3yM6ZP4+m7unTGNs9606 intact-crc:5B2527089B5710B6|rigid:13anCpPEJYiB0tB5LzQ9S5O5LCI false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q9UER7 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-77321|ensembl:ENSP00000266000|ensembl:ENSP00000363668|ensembl:ENSP00000372539|ensembl:ENSP00000372681|ensembl:ENSP00000382014|ensembl:ENSP00000382281|ensembl:ENSP00000394108|ensembl:ENSP00000404376|ensembl:ENSP00000404623|ensembl:ENSP00000410772|uniprotkb:O14747|uniprotkb:O15141|uniprotkb:O15208|uniprotkb:Q9BWI3|uniprotkb:B4E1I3|uniprotkb:F5H082|uniprotkb:Q5STK9|uniprotkb:F5ANJ6|uniprotkb:F5ANJ7 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:daxx_human(display_long)|uniprotkb:DAXX(gene name)|psi-mi:DAXX(display_short)|uniprotkb:BING2(gene name synonym)|uniprotkb:DAP6(gene name synonym)|uniprotkb:Daxx(gene name synonym)|uniprotkb:Fas death domain-associated protein(gene name synonym)|uniprotkb:ETS1-associated protein 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091888|imex:IM-21827-231 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) ensembl:ENSG00000206206(gene)|ensembl:ENSG00000206279(gene)|ensembl:ENSG00000227046(gene)|ensembl:ENSG00000231617(gene)|ensembl:ENSG00000204209(gene)|ensembl:ENST00000266000(transcript)|ensembl:ENST00000374542(transcript)|ensembl:ENST00000383062(transcript)|ensembl:ENST00000383194(transcript)|ensembl:ENST00000399060(transcript)|ensembl:ENST00000399344(transcript)|ensembl:ENST00000433482(transcript)|ensembl:ENST00000436311(transcript)|ensembl:ENST00000445009(transcript)|ensembl:ENST00000455860(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002039"(p53 binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0072738"(cellular response to diamide)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903936"(cellular response to sodium arsenite)|interpro:IPR005012(Daxx protein)|interpro:IPR031333|interpro:IPR038298|mint:Q9UER7|rcsb pdb:2KQS|rcsb pdb:2KZS|rcsb pdb:2KZU|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:5GRQ|rcsb pdb:5KDM|rcsb pdb:5Y18|rcsb pdb:5Y6O|reactome:R-HSA-3899300|reactome:R-HSA-6804757|reactome:R-HSA-9609690|reactome:R-HSA-9670095|reactome:R-HSA-9670613|reactome:R-HSA-9670615|refseq:NP_001135441.1|refseq:NP_001341.1|refseq:NP_001241646.1|dip:DIP-27628N|uniprotkb:Q9UER7(identity)|entrezgene/locuslink:1616(identity)|ddbj/embl/genbank:BC109074(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:lM3F/1ay7qvt8NkGWvgfSvBX1qQ9606 intact-crc:C57BD5E5E7225BA3|rigid:s+Wo+WgLyuTdkwmctcpVURvjZ6I false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9P2J8-2 uniprotkb:Q8IUH5 intact:EBI-9091871 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:q9p2j8-2(display_long)|uniprotkb:KIAA1349(gene name synonym)|uniprotkb:ZNF624(gene name)|psi-mi:ZNF624(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091868|imex:IM-21827-230 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-9116427(isoform-parent)|uniprotkb:Q9P2J8-2(isoform-parent)|uniprotkb:Q9P2J8-2(identity)|ddbj/embl/genbank:BC103944(identity)|entrezgene/locuslink:57547(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:ka3WAgvNLucLX7PZ1YJ9I/HCCUw9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:7E3C028846C78C1D|rigid:RnIvx8dsdb2MQeSysbqWzU17/UU false - sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q9UKA8 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9091952|uniprotkb:A4GU14|uniprotkb:Q9UKA7|uniprotkb:E7ENV1|uniprotkb:Q5ECL3|uniprotkb:A4LA69|uniprotkb:Q5TGC6|uniprotkb:E7EWD8|uniprotkb:Q9NUC8|uniprotkb:E3VWE2|uniprotkb:E5L4P0|uniprotkb:E5L4P7|uniprotkb:G1FI66|uniprotkb:G1FLF0|ensembl:ENSP00000363516|ensembl:ENSP00000445401 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:rcan3_human(display_long)|uniprotkb:DSCR1L2(gene name synonym)|uniprotkb:Down syndrome candidate region 1-like protein 2(gene name synonym)|uniprotkb:Myocyte-enriched calcineurin-interacting protein 3(gene name synonym)|uniprotkb:Regulator of calcineurin 3(gene name synonym)|uniprotkb:RCAN3(gene name)|psi-mi:RCAN3(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091964|imex:IM-21827-235 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_001238911.1|refseq:NP_001238912.1|refseq:NP_001238914.1|refseq:NP_038469.1|refseq:NP_001238906.1|refseq:NP_001238907.1|refseq:NP_001238908.1|refseq:NP_001238909.1|refseq:NP_001238910.1|refseq:NP_001238913.1|ensembl:ENSG00000117602(gene)|ensembl:ENST00000374395(transcript)|ensembl:ENST00000538532(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008597"(calcium-dependent protein serine/threonine phosphatase regulator activity)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031013"(troponin I binding)|interpro:IPR006931(Calcipressin)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034923|interpro:IPR035979|uniprotkb:Q9UKA8(identity)|ddbj/embl/genbank:BC035854(identity)|entrezgene/locuslink:11123(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:GcjmPxKst3ISAOr1WMhJLrYq8JY9606 intact-crc:84282D0ABBE41696|rigid:jSfQvAJtY+sG1kusEooidnv43q8 false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UI08-2 uniprotkb:Q8IUH5 intact:EBI-6448852|ensembl:ENSP00000376652 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:q9ui08-2(display_long)|uniprotkb:EVL(gene name)|psi-mi:EVL(display_short)|uniprotkb:Ena/vasodilator-stimulated phosphoprotein-like(gene name synonym)|uniprotkb:RNB6(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091936|imex:IM-21827-234 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-346653(isoform-parent)|uniprotkb:Q9UI08-2(isoform-parent)|ensembl:ENSG00000196405(gene)|ensembl:ENST00000392920(transcript)|uniprotkb:Q9UI08-2(identity)|ddbj/embl/genbank:BC032358(identity)|entrezgene/locuslink:51466(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:vlsreFW75TROSmoknoqbohf76HY9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:E0A780C92F498789|rigid:y3jD+lQ8lS1wU42U31Xt2VQeHfI false - sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q9UHY8 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-396453|uniprotkb:Q76LN0|uniprotkb:Q99690|uniprotkb:Q5EBN3|intact:EBI-28984869|ensembl:ENSP00000385112 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:fez2_human(display_long)|uniprotkb:FEZ2(gene name)|psi-mi:FEZ2(display_short)|uniprotkb:Zygin-2(gene name synonym)|uniprotkb:Zygin II(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091920|imex:IM-21827-233 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_001036013.1|refseq:NP_005093.2|ensembl:ENST00000379245|ensembl:ENSP00000368547|ensembl:ENSP00000385112|ensembl:ENSG00000171055(gene)|ensembl:ENST00000405912(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0030424"(axon)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR011680(FEZ-like)|interpro:IPR015641(Fasciculation and elongation protein zeta 2)|mint:Q9UHY8|uniprotkb:Q9UHY8(identity)|ddbj/embl/genbank:BC110386(identity)|entrezgene/locuslink:9637(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:n5uH+vdgrrvmI+PYkcMUEnAzxwE9606 intact-crc:9CFC04450C9851CE|rigid:GO+MMpsXWNWtmeuSVCaqXwlLXpU false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q9UQB8-6 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9092016 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:q9uqb8-6(display_long)|uniprotkb:Fas ligand-associated factor 3(gene name synonym)|uniprotkb:Insulin receptor substrate p53/p58(gene name synonym)|uniprotkb:Insulin receptor substrate protein of 53 kDa(gene name synonym)|uniprotkb:BAIAP2(gene name)|psi-mi:BAIAP2(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9092020|imex:IM-21827-238 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) intact:EBI-525456(isoform-parent)|uniprotkb:Q9UQB8-6(isoform-parent)|uniprotkb:Q9UQB8-6(identity)|entrezgene/locuslink:10458(identity)|ddbj/embl/genbank:BC014020(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:n2iqdXaDCA6aLxGI9wl3/44N3ws9606 intact-crc:89FA8E03875F754F|rigid:ypBwBKFhpwngfRzmRPXEDAGu8nI false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q9UQB8-3 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9091996|ensembl:ENSP00000458964 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:q9uqb8-3(display_long)|uniprotkb:Fas ligand-associated factor 3(gene name synonym)|uniprotkb:Insulin receptor substrate p53/p58(gene name synonym)|uniprotkb:Insulin receptor substrate protein of 53 kDa(gene name synonym)|uniprotkb:BAIAP2(gene name)|psi-mi:BAIAP2(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9092000|imex:IM-21827-237 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) intact:EBI-525456(isoform-parent)|ensembl:ENSG00000175866(gene)|ensembl:ENST00000575712(transcript)|uniprotkb:Q9UQB8-3(isoform-parent)|uniprotkb:Q9UQB8-3(identity)|ddbj/embl/genbank:BC032559(identity)|entrezgene/locuslink:10458(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:w60JYLTu20jqqHSqrbqjkPon5k49606 intact-crc:C616914120CF9CD6|rigid:/dt81vaIrPbukGSQptbg3LMAy5o false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UMW8 uniprotkb:Q8IUH5 intact:EBI-356206|uniprotkb:Q9NY71|uniprotkb:Q6IAD9|ensembl:ENSP00000215794|uniprotkb:Q53Y90 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:ubp18_human(display_long)|uniprotkb:USP18(gene name)|psi-mi:USP18(display_short)|uniprotkb:ISG43(gene name synonym)|uniprotkb:ISG15-specific-processing protease(gene name synonym)|uniprotkb:43 kDa ISG15-specific protease(gene name synonym)|uniprotkb:Ubl thioesterase 18(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9091980|imex:IM-21827-236 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_059110.2|ensembl:ENSG00000184979(gene)|ensembl:ENST00000215794(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019785"(ISG15-specific protease activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR038765|mint:Q9UMW8|reactome:R-HSA-1169408|reactome:R-HSA-5689880|reactome:R-HSA-912694|dip:DIP-42723N|uniprotkb:Q9UMW8(identity)|entrezgene/locuslink:11274(identity)|ddbj/embl/genbank:BC014896(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:f8gp0LV11CoEQvSGwbUVMEwRd+U9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:6325AEE6DE5188BB|rigid:21A41F0pBUT0XPkcI5EivIMeRPI false - sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q9Y448 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-373334|uniprotkb:Q147U5|uniprotkb:Q32Q57|uniprotkb:Q5ISJ0|uniprotkb:Q6P2S5|uniprotkb:Q6PJM0|uniprotkb:Q86XB4|uniprotkb:B4DXA7|ensembl:ENSP00000249776|intact:EBI-2555320 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:skap_human(display_long)|uniprotkb:KNSTRN(gene name)|psi-mi:KNSTRN(display_short)|uniprotkb:C15orf23(gene name synonym)|uniprotkb:Kinetochore-localized astrin-binding protein(gene name synonym)|uniprotkb:Kinetochore-localized astrin/SPAG5-binding protein(gene name synonym)|uniprotkb:SKAP(gene name synonym)|uniprotkb:TRAF4-associated factor 1(gene name synonym)|uniprotkb:TRAF4AF1(gene name synonym)|uniprotkb:HSD11(orf name) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9092074|imex:IM-21827-241 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_001136233.1|refseq:NP_001136234.1|refseq:NP_150628.3|ensembl:ENSG00000128944(gene)|ensembl:ENST00000249776(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|dip:DIP-31247N|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0001726"(ruffle)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007051"(spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016477"(cell migration)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051301"(cell division)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0072686"(mitotic spindle)|interpro:IPR033373|uniprotkb:Q9Y448(identity)|entrezgene/locuslink:90417(identity)|ddbj/embl/genbank:BC118639(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:48DI5G7v8vAeEMOZpyhAOcmFhc49606 intact-crc:F59F9742392BAFBF|rigid:vQtoL6oa1nHK9Q8VfgAlHZfZntM false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q9Y3D2 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9092052|uniprotkb:Q17R44|uniprotkb:Q9Y5W6|uniprotkb:Q4G1C7|ensembl:ENSP00000365693 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:msrb2_human(display_long)|uniprotkb:CBS-1(gene name synonym)|uniprotkb:MSRB(gene name synonym)|uniprotkb:CGI-131(orf name)|uniprotkb:MSRB2(gene name)|psi-mi:MSRB2(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9092059|imex:IM-21827-240 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_036360.3|ensembl:ENSG00000148450(gene)|ensembl:ENST00000376510(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030091"(protein repair)|go:"GO:0033743"("peptide-methionine (R)-S-oxide reductase activity")|go:"GO:0033745"("L-methionine-(R)-S-oxide reductase activity")|interpro:IPR002579(Methionine sulphoxide reductase B)|interpro:IPR011057(Mss4-like)|interpro:IPR028427|reactome:R-HSA-5676934|uniprotkb:Q9Y3D2(identity)|entrezgene/locuslink:22921(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:8fyFocjIZK3Uq4nM4WLFU+1GrYA9606 intact-crc:7161761AD6362FC5|rigid:X1HA2KrggAt5gwLKF2NqkpSe9eI false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y231 uniprotkb:Q8IUH5 intact:EBI-3922408|uniprotkb:Q5T0W4|ensembl:ENSP00000302599 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:fut9_human(display_long)|uniprotkb:FUT9(gene name)|psi-mi:FUT9(display_short)|uniprotkb:Fucosyltransferase 9(gene name synonym)|uniprotkb:Fucosyltransferase IX(gene name synonym)|uniprotkb:Galactoside 3-L-fucosyltransferase(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9092036|imex:IM-21827-239 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011533685.1|refseq:XP_011533687.1|refseq:NP_006572.2|ensembl:ENSG00000172461(gene)|ensembl:ENST00000302103(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006486"(protein glycosylation)|go:"GO:0008417"(fucosyltransferase activity)|go:"GO:0009312"(oligosaccharide biosynthetic process)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017083"(4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity)|go:"GO:0030182"(neuron differentiation)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0033692"(cellular polysaccharide biosynthetic process)|go:"GO:0036065"(fucosylation)|go:"GO:0042355"(L-fucose catabolic process)|go:"GO:0046920"("alpha-(1->3)-fucosyltransferase activity")|go:"GO:1903037"(regulation of leukocyte cell-cell adhesion)|go:"GO:1903236"(regulation of leukocyte tethering or rolling)|interpro:IPR001503(Glycosyl transferase, family 10)|interpro:IPR031481|interpro:IPR038577|reactome:R-HSA-9037629|refseq:XP_016865677.1|refseq:XP_016865679.1|uniprotkb:Q9Y231(identity)|ddbj/embl/genbank:BC036101(identity)|entrezgene/locuslink:10690(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:aGVYUHvuN69Gw/82upRlQgdeatk9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:D05252AC87175D67|rigid:bAaOofdemk+cL200ZXhfzgcXNPk false - sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:F6TR53 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9092124|ensembl:ENSP00000384984 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:f6tr53_human(display_long)|uniprotkb:HS1BP3(gene name)|psi-mi:HS1BP3(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9092121|imex:IM-21827-244 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) ensembl:ENSG00000118960(gene)|ensembl:ENST00000402541(transcript)|go:"GO:0035091"(phosphatidylinositol binding)|interpro:IPR001683(Phox-like)|interpro:IPR036871|interpro:IPR037901|interpro:IPR039701|uniprotkb:F6TR53(identity)|ddbj/embl/genbank:BC027947(identity)|entrezgene/locuslink:64342(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:QKAslE6zdqwG4fLaCvK8QXiluJc9606 intact-crc:E3B7E1DBC672DDE4|rigid:6cmXqurVW9tAA1m7whFsKaAKK/k false sufficient binding region:1-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q9Y6W5 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-4290615|uniprotkb:O60794|uniprotkb:Q9UDY7|intact:EBI-28973998|ensembl:ENSP00000483313|uniprotkb:B4DZN0 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:wasf2_human(display_long)|uniprotkb:WASF2(gene name)|psi-mi:WASF2(display_short)|uniprotkb:WAVE2(gene name synonym)|uniprotkb:Protein WAVE-2(gene name synonym)|uniprotkb:Verprolin homology domain-containing protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9092106|imex:IM-21827-243 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_008921.1|ensembl:ENST00000536657|ensembl:ENSP00000439883|ensembl:ENSP00000483313|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR028288|mint:Q9Y6W5|rcsb pdb:2A40|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|reactome:R-HSA-9664422|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|ensembl:ENSG00000158195(gene)|ensembl:ENST00000618852(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0001726"(ruffle)|go:"GO:0003779"(actin binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006897"(endocytosis)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0031209"(SCAR complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0072673"(lamellipodium morphogenesis)|refseq:NP_001188333.1|dip:DIP-41817N|uniprotkb:Q9Y6W5(identity)|entrezgene/locuslink:10163(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:lRPT4syjPdKz2JoqWQQm3xw4hWc9606 intact-crc:73A784E17856AA55|rigid:d+RW/+/MO8VbQ9+yFVJbF2sKAnM false sufficient binding region:64-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y605 uniprotkb:Q8IUH5 intact:EBI-995714|uniprotkb:B3KVT2|ensembl:ENSP00000318352|ensembl:ENSP00000372024|ensembl:ENSP00000422065|uniprotkb:D3DVT3 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:mofa1_human(display_long)|uniprotkb:PGR1(gene name synonym)|uniprotkb:Protein PGR1(gene name synonym)|uniprotkb:Protein associated with MRG of 14 kDa(gene name synonym)|uniprotkb:MRFAP1(gene name)|psi-mi:MRFAP1(display_short)|uniprotkb:PAM14(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9092090|imex:IM-21827-242 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_150638.1|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR029254|mint:Q9Y605|ensembl:ENSG00000179010(gene)|ensembl:ENST00000320912(transcript)|ensembl:ENST00000382581(transcript)|ensembl:ENST00000507420(transcript)|go:"GO:0005654"(nucleoplasm)|refseq:NP_001258982.1|uniprotkb:Q9Y605(identity)|entrezgene/locuslink:93621(identity)|ddbj/embl/genbank:BC022797(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:qsRG2MjlSzgcyuUj0/45kBNrfw89606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:96E983C6543283D8|rigid:gdfeS3JGz/FKpFkMJdbM0arE86Q false - sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:O60902-3 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9092164|ensembl:ENSP00000374240 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:o60902-3(display_long)|uniprotkb:Homeobox protein Og12X(gene name synonym)|uniprotkb:OG12X(gene name synonym)|uniprotkb:Paired-related homeobox protein SHOT(gene name synonym)|uniprotkb:SHOT(gene name synonym)|uniprotkb:SHOX2(gene name)|psi-mi:SHOX2(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9092161|imex:IM-21827-246 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) intact:EBI-5278206(isoform-parent)|uniprotkb:O60902-3(isoform-parent)|ensembl:ENSG00000168779(gene)|ensembl:ENST00000389589(transcript)|uniprotkb:O60902-3(identity)|ddbj/embl/genbank:BC008829(identity)|entrezgene/locuslink:6474(identity) psi-mi:"MI:0469"(intact) - isoform-comment:No experimental confirmation available. figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:c0otR/p6G5GswndW3Ix9OYTd37M9606 intact-crc:95B2A872A5EB1030|rigid:htOvAUOhNNRImQ6OPn+uY+30p2g false sufficient binding region:1-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:I6L9D0 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9092141 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:i6l9d0_human(display_long)|uniprotkb:TTLL7(gene name)|psi-mi:TTLL7(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9092145|imex:IM-21827-245 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) interpro:IPR004344(Tubulin-tyrosine ligase)|go:"GO:0006464"(cellular protein modification process)|uniprotkb:I6L9D0(identity)|ddbj/embl/genbank:BC048970(identity)|entrezgene/locuslink:79739(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:p0/ZjaSvjCfpDFv7kxSYCWsC1vI9606 intact-crc:6B511FE68A6F0E97|rigid:PGptjfqkNXmnKL5TBKtzxV9uEBM false sufficient binding region:1-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q9Y294 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-749553|uniprotkb:Q6IA08|uniprotkb:Q9P014|ensembl:ENSP00000229595 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:asf1a_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog A(gene name synonym)|uniprotkb:CCG1-interacting factor A(gene name synonym)|uniprotkb:ASF1A(gene name)|psi-mi:ASF1A(display_short)|uniprotkb:CGI-98(orf name)|uniprotkb:HSPC146(orf name) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9092227|imex:IM-21827-249 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_054753.1|dip:DIP-29241N|ensembl:ENSG00000111875(gene)|ensembl:ENST00000229595(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0042692"(muscle cell differentiation)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9Y294|rcsb pdb:1TEY|rcsb pdb:2I32|rcsb pdb:2IIJ|rcsb pdb:2IO5|rcsb pdb:3AAD|rcsb pdb:5C3I|rcsb pdb:6F0G|rcsb pdb:6F0H|rcsb pdb:6ZUF|reactome:R-HSA-2559584|rcsb pdb:6F0F|uniprotkb:Q9Y294(identity)|entrezgene/locuslink:25842(identity)|ddbj/embl/genbank:BC010878(identity) psi-mi:"MI:0469"(intact) - caution:This sequence has been withdrawn from Uniprot. figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:rIMptRSOYD+wfp0dMEHjhNNsHXQ9606 intact-crc:FA55DC4F76056672|rigid:wvravOim/IjoEnT0Wrc4PrMkqrY false sufficient binding region:1-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q92835-2 uniprotkb:Q8IUH5 intact:EBI-9092209|ensembl:ENSP00000352575|ensembl:ENSP00000486669 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:q92835-2(display_long)|uniprotkb:Inositol polyphosphate-5-phosphatase of 145 kDa(gene name synonym)|uniprotkb:SH2 domain-containing inositol 5'-phosphatase 1(gene name synonym)|uniprotkb:SHIP(gene name synonym)|uniprotkb:SHIP1(gene name synonym)|uniprotkb:p150Ship(gene name synonym)|uniprotkb:INPP5D(gene name)|psi-mi:INPP5D(display_short)|uniprotkb:Inositol polyphosphate-5-phosphatase D(gene name synonym)|uniprotkb:Phosphatidylinositol 4,5-bisphosphate 5-phosphatase(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9092206|imex:IM-21827-248 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1380477(isoform-parent)|uniprotkb:Q92835-2(isoform-parent)|ensembl:ENSG00000168918(gene)|ensembl:ENSG00000281614(gene)|ensembl:ENST00000359570(transcript)|ensembl:ENST00000629761(transcript)|uniprotkb:Q92835-2(identity)|entrezgene/locuslink:3635(identity)|ddbj/embl/genbank:BC113580(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:c8rH1tSqxoSR0vD2pTnlRPGRfiU9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:9A4C04894C0490E0|rigid:iVbit1srPyigYhTIi57qPuBUvSk false - sufficient binding region:1-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q8IVB4 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9092184|uniprotkb:Q5JPI6|uniprotkb:Q3LIC2|uniprotkb:Q8NAB9|uniprotkb:A6NMQ9|uniprotkb:Q5WA58|ensembl:ENSP00000320246 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:sl9a9_human(display_long)|uniprotkb:NHE9(gene name synonym)|uniprotkb:"Na(+)/H(+) exchanger 9"(gene name synonym)|uniprotkb:Solute carrier family 9 member 9(gene name synonym)|uniprotkb:Nbla00118(orf name)|uniprotkb:SLC9A9(gene name)|psi-mi:SLC9A9(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9092181|imex:IM-21827-247 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_775924.1|ensembl:ENSG00000181804(gene)|ensembl:ENST00000316549(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015385"("sodium:proton antiporter activity")|go:"GO:0015386"("potassium:proton antiporter activity")|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0055037"(recycling endosome)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0098719"(sodium ion import across plasma membrane)|interpro:IPR002090("Na+/H+ exchanger, isoform 6 (NHE6)")|interpro:IPR004709(Sodium/hydrogen exchanger subfamily)|interpro:IPR006153(Sodium/hydrogen exchanger)|interpro:IPR018416|interpro:IPR018422|reactome:R-HSA-425986|reactome:R-HSA-5619052|uniprotkb:Q8IVB4(identity)|ddbj/embl/genbank:BC035779(identity)|entrezgene/locuslink:285195(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:2B4SJ+84yiMM5/+Wkuic5hShCik9606 intact-crc:9FA2B471591D41B3|rigid:hFNAxmd/bWp9HmGRsDrbo6yjiHw false sufficient binding region:1-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q9Y3D2 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9092052|uniprotkb:Q17R44|uniprotkb:Q9Y5W6|uniprotkb:Q4G1C7|ensembl:ENSP00000365693 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:msrb2_human(display_long)|uniprotkb:CBS-1(gene name synonym)|uniprotkb:MSRB(gene name synonym)|uniprotkb:CGI-131(orf name)|uniprotkb:MSRB2(gene name)|psi-mi:MSRB2(display_short) psi-mi:"MI:0397"(two hybrid array) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9092243|imex:IM-21827-250 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_036360.3|ensembl:ENSG00000148450(gene)|ensembl:ENST00000376510(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030091"(protein repair)|go:"GO:0033743"("peptide-methionine (R)-S-oxide reductase activity")|go:"GO:0033745"("L-methionine-(R)-S-oxide reductase activity")|interpro:IPR002579(Methionine sulphoxide reductase B)|interpro:IPR011057(Mss4-like)|interpro:IPR028427|reactome:R-HSA-5676934|uniprotkb:Q9Y3D2(identity)|entrezgene/locuslink:22921(identity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:8fyFocjIZK3Uq4nM4WLFU+1GrYA9606 intact-crc:117C0D7BCFBC3F93|rigid:X1HA2KrggAt5gwLKF2NqkpSe9eI false sufficient binding region:1-487("MI:0442") - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q924S8 uniprotkb:Q8IUH5 intact:EBI-9094489|uniprotkb:Q3U2W6|uniprotkb:Q6PET8|ensembl:ENSMUSP00000028829 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:spre1_mouse(display_long)|uniprotkb:Spred1(gene name)|psi-mi:Spred1(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-9094592|imex:IM-21827-362 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001264185.1|refseq:NP_277059.1|ensembl:ENSMUSG00000027351(gene)|ensembl:ENSMUST00000028829(transcript)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0005173"(stem cell factor receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0060979"(vasculogenesis involved in coronary vascular morphogenesis)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:1902747"(negative regulation of lens fiber cell differentiation)|interpro:IPR000697(EVH1)|interpro:IPR007875(Sprouty)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023337|interpro:IPR041937|reactome:R-MMU-5658442|reactome:R-MMU-5658623|genbank identifier:NM_033524(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J go:"GO:0031982"(vesicle) - - figure legend:6a|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2013/12/19 2014/10/16 rogid:5xbClCw4wvGBopgNt2r7NnGckfI10090 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:908F11D4D6BB0AC3|rigid:8XPPdKLs0WUZhXAXv8WJAe1AMas false flag tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q6P6N5 uniprotkb:Q8IUH5 intact:EBI-9094545|uniprotkb:Q7TNJ8 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:spre3_mouse(display_long)|uniprotkb:Spred3(gene name)|psi-mi:Spred3(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-9094590|imex:IM-21827-361 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR041937|mint:Q6P6N5|refseq:NP_891557.3|interpro:IPR023337|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR007875(Sprouty)|interpro:IPR000697(EVH1)|refseq:XP_006539516.1|refseq:XP_006539517.1|refseq:XP_006539518.1|refseq:XP_006539519.1|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:1902747"(negative regulation of lens fiber cell differentiation)|reactome:R-MMU-5658442|genbank identifier:NM_182927(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J go:"GO:0005794"(Golgi apparatus) - - figure legend:6b|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2013/12/19 2014/10/16 rogid:NXhyQ64E96hrWm5caGb1ezdw8Vk10090 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:1C9C2C989B74A6D8|rigid:v9DvhdGXn1yHb/ShDrXZ+iaNuOw false flag tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:P51674 uniprotkb:Q8IUH5 intact:EBI-7187133|ensembl:ENSP00000280187|ensembl:ENSP00000377268|intact:UNK-5379643|uniprotkb:Q92602|uniprotkb:E9PHI5|uniprotkb:B7Z642 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:gpm6a_human(display_long)|uniprotkb:GPM6A(gene name)|psi-mi:GPM6A(display_short)|uniprotkb:M6A(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-9094588|imex:IM-21827-360 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000150625(gene)|ensembl:ENST00000280187(transcript)|ensembl:ENST00000393658(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003407"(neural retina development)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007416"(synapse assembly)|go:"GO:0009617"(response to bacterium)|go:"GO:0030175"(filopodium)|go:"GO:0031175"(neuron projection development)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044295"(axonal growth cone)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR001614(Myelin proteolipid protein PLP)|interpro:IPR018237|refseq:NP_001248377.1|refseq:NP_963885.1|refseq:NP_005268.1|refseq:NP_963886.1|genbank identifier:NM_005277(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J go:"GO:0005794"(Golgi apparatus) comment:mint|comment:homomint - figure legend:6c|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2013/12/19 2014/10/16 rogid:6h/p/+l8WRhJ9HsGcbxleQuDtSo9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:51F3B59C6462EE06|rigid:LqEIwgfaRcyLZlpgZ3CzWDM5ChA false flag tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q924S8 uniprotkb:Q8IUH5 intact:EBI-9094489|uniprotkb:Q3U2W6|uniprotkb:Q6PET8|ensembl:ENSMUSP00000028829 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:spre1_mouse(display_long)|uniprotkb:Spred1(gene name)|psi-mi:Spred1(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9094487|imex:IM-21827-356 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001264185.1|refseq:NP_277059.1|ensembl:ENSMUSG00000027351(gene)|ensembl:ENSMUST00000028829(transcript)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0005173"(stem cell factor receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0060979"(vasculogenesis involved in coronary vascular morphogenesis)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:1902747"(negative regulation of lens fiber cell differentiation)|interpro:IPR000697(EVH1)|interpro:IPR007875(Sprouty)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023337|interpro:IPR041937|reactome:R-MMU-5658442|reactome:R-MMU-5658623|genbank identifier:NM_033524(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J - - - figure legend:4a|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:5xbClCw4wvGBopgNt2r7NnGckfI10090 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:5C13AAAE4A4F5240|rigid:8XPPdKLs0WUZhXAXv8WJAe1AMas false flag tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q6P6N5 uniprotkb:Q8IUH5 intact:EBI-9094545|uniprotkb:Q7TNJ8 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:spre3_mouse(display_long)|uniprotkb:Spred3(gene name)|psi-mi:Spred3(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9094531|imex:IM-21827-357 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR041937|mint:Q6P6N5|refseq:NP_891557.3|interpro:IPR023337|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR007875(Sprouty)|interpro:IPR000697(EVH1)|refseq:XP_006539516.1|refseq:XP_006539517.1|refseq:XP_006539518.1|refseq:XP_006539519.1|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:1902747"(negative regulation of lens fiber cell differentiation)|reactome:R-MMU-5658442|genbank identifier:NM_182927(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J - - - figure legend:4b|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:NXhyQ64E96hrWm5caGb1ezdw8Vk10090 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:902206902592FB41|rigid:v9DvhdGXn1yHb/ShDrXZ+iaNuOw false flag tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P51674 uniprotkb:Q8IUH5 intact:EBI-7187133|ensembl:ENSP00000280187|ensembl:ENSP00000377268|intact:UNK-5379643|uniprotkb:Q92602|uniprotkb:E9PHI5|uniprotkb:B7Z642 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:gpm6a_human(display_long)|uniprotkb:GPM6A(gene name)|psi-mi:GPM6A(display_short)|uniprotkb:M6A(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9094560|imex:IM-21827-358 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000150625(gene)|ensembl:ENST00000280187(transcript)|ensembl:ENST00000393658(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003407"(neural retina development)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007416"(synapse assembly)|go:"GO:0009617"(response to bacterium)|go:"GO:0030175"(filopodium)|go:"GO:0031175"(neuron projection development)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044295"(axonal growth cone)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR001614(Myelin proteolipid protein PLP)|interpro:IPR018237|refseq:NP_001248377.1|refseq:NP_963885.1|refseq:NP_005268.1|refseq:NP_963886.1|genbank identifier:NM_005277(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J - comment:mint|comment:homomint - figure legend:4c|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:6h/p/+l8WRhJ9HsGcbxleQuDtSo9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:ADEC16B3F89E75B4|rigid:LqEIwgfaRcyLZlpgZ3CzWDM5ChA false flag tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8IUH5 uniprotkb:Q96CV9 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9094570|imex:IM-21827-359 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N|genbank identifier:NM_001008211(identity) - - - figure legend:4d|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2018/04/06 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606 intact-crc:9B953F9B97566E71|rigid:muekOPuUfedz04r58AHASfJ2SYc false green fluorescent protein tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9UQB8-3 uniprotkb:Q8IUH5 intact:EBI-9091996|ensembl:ENSP00000458964 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:q9uqb8-3(display_long)|uniprotkb:Fas ligand-associated factor 3(gene name synonym)|uniprotkb:Insulin receptor substrate p53/p58(gene name synonym)|uniprotkb:Insulin receptor substrate protein of 53 kDa(gene name synonym)|uniprotkb:BAIAP2(gene name)|psi-mi:BAIAP2(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9100082|imex:IM-21827-363 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-525456(isoform-parent)|ensembl:ENSG00000175866(gene)|ensembl:ENST00000575712(transcript)|uniprotkb:Q9UQB8-3(isoform-parent)|uniprotkb:Q9UQB8-3(identity)|entrezgene/locuslink:10458(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:w60JYLTu20jqqHSqrbqjkPon5k49606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:317BC24BE2A82AFD|rigid:/dt81vaIrPbukGSQptbg3LMAy5o false tandem tag:n-n("MI:0677") sufficient binding region:64-487("MI:0442")|firefly luciferase protein tag:n-n("MI:1208") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-9087227 uniprotkb:Q8IUH5 - intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:fkbp6-like_human(display_short)|psi-mi:EBI-9087227(display_long) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9100103|imex:IM-21827-364 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) entrezgene/locuslink:8468(identity)|intact:EBI-9087227(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:u6bY9hpLjQ3Lqx5ydjbFZQAvf1g9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:775E2D91D89B099F|rigid:uvPYLO86M+b68zgAVNysbQ+xlzU false tandem tag:n-n("MI:0677") firefly luciferase protein tag:n-n("MI:1208")|sufficient binding region:1-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q8IVB4 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9092184|uniprotkb:Q5JPI6|uniprotkb:Q3LIC2|uniprotkb:Q8NAB9|uniprotkb:A6NMQ9|uniprotkb:Q5WA58|ensembl:ENSP00000320246 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:sl9a9_human(display_long)|uniprotkb:NHE9(gene name synonym)|uniprotkb:"Na(+)/H(+) exchanger 9"(gene name synonym)|uniprotkb:Solute carrier family 9 member 9(gene name synonym)|uniprotkb:Nbla00118(orf name)|uniprotkb:SLC9A9(gene name)|psi-mi:SLC9A9(display_short) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9100145|imex:IM-21827-366 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_775924.1|ensembl:ENSG00000181804(gene)|ensembl:ENST00000316549(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015385"("sodium:proton antiporter activity")|go:"GO:0015386"("potassium:proton antiporter activity")|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0055037"(recycling endosome)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0098719"(sodium ion import across plasma membrane)|interpro:IPR002090("Na+/H+ exchanger, isoform 6 (NHE6)")|interpro:IPR004709(Sodium/hydrogen exchanger subfamily)|interpro:IPR006153(Sodium/hydrogen exchanger)|interpro:IPR018416|interpro:IPR018422|reactome:R-HSA-425986|reactome:R-HSA-5619052|uniprotkb:Q8IVB4(identity)|entrezgene/locuslink:285195(identity) psi-mi:"MI:0469"(intact) - - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:2B4SJ+84yiMM5/+Wkuic5hShCik9606 intact-crc:420488A917B0EB1B|rigid:hFNAxmd/bWp9HmGRsDrbo6yjiHw false firefly luciferase protein tag:n-n("MI:1208")|sufficient binding region:64-487("MI:0442") tandem tag:n-n("MI:0677") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q9NP61 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-2875816|ensembl:ENSP00000263245|uniprotkb:Q9Y4V4|uniprotkb:Q9NUP5|uniprotkb:Q9Y4V3|uniprotkb:Q9NT10|uniprotkb:Q9BSC6|uniprotkb:Q9H9J0|uniprotkb:E9PB03 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:arfg3_human(display_long)|uniprotkb:ARFGAP3(gene name)|psi-mi:ARFGAP3(display_short)|uniprotkb:ARFGAP1(gene name synonym) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9100166|imex:IM-21827-367 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) ensembl:ENSG00000242247(gene)|ensembl:ENST00000263245(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0009306"(protein secretion)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0048205"(COPI coating of Golgi vesicle)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR037278|interpro:IPR038508|rcsb pdb:2CRW|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-9013148|reactome:R-HSA-9013408|go:"GO:0005096"(GTPase activator activity)|refseq:NP_001135765.1|refseq:NP_055385.3|uniprotkb:Q9NP61(identity)|entrezgene/locuslink:26286(identity) psi-mi:"MI:0469"(intact) - - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:1868s5elsn/sX/f8if3lmbLxKxg9606 intact-crc:E605E5FC1331F9D2|rigid:ZyzrmLJFEOOHi+THbM0Iaw5AiCw false sufficient binding region:1-487("MI:0442")|firefly luciferase protein tag:n-n("MI:1208") tandem tag:n-n("MI:0677") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P48730-2 uniprotkb:Q8IUH5 intact:EBI-9087876|ensembl:ENSP00000376146 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:p48730-2(display_long)|uniprotkb:HCKID(gene name synonym)|uniprotkb:Tau-protein kinase CSNK1D(gene name synonym)|uniprotkb:CSNK1D(gene name)|psi-mi:CSNK1D(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9100124|imex:IM-21827-365 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-751621(isoform-parent)|ensembl:ENSG00000141551(gene)|ensembl:ENST00000392334(transcript)|uniprotkb:P48730-2(isoform-parent)|uniprotkb:P48730-2(identity)|entrezgene/locuslink:1453(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:DKYeQTtdg+u5Gm9wscDkiTs7Blg9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:8EEAE86E013D20CC|rigid:yI9cncQsphvllXDDNHnH3oz7OZ8 false tandem tag:n-n("MI:0677") sufficient binding region:1-487("MI:0442")|firefly luciferase protein tag:n-n("MI:1208") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08499-8 uniprotkb:Q8IUH5 intact:EBI-9090666|ensembl:ENSP00000321739 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:q08499-8(display_long)|uniprotkb:DPDE3(gene name synonym)|uniprotkb:PDE43(gene name synonym)|uniprotkb:PDE4D6(isoform synonym)|uniprotkb:PDE4D(gene name)|psi-mi:PDE4D(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9100229|imex:IM-21827-370 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1642831(isoform-parent)|uniprotkb:Q08499-8(isoform-parent)|ensembl:ENSG00000113448(gene)|ensembl:ENST00000317118(transcript)|uniprotkb:Q08499-8(identity)|entrezgene/locuslink:5144(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:LuLHIM+zWL+8B9s//iZdfoQXOhw9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:BF7FF3531137AA15|rigid:n7VWkue5xV7aVYANvAVOpSVWn8w false tandem tag:n-n("MI:0677") firefly luciferase protein tag:n-n("MI:1208")|sufficient binding region:1-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q7Z5R6 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-2818084|intact:EBI-9091217|uniprotkb:Q8IYL7|uniprotkb:Q8IWS8|uniprotkb:Q8IZZ7|ensembl:ENSP00000365411 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:ab1ip_human(display_long)|uniprotkb:APBB1IP(gene name)|psi-mi:APBB1IP(display_short)|uniprotkb:PREL1(gene name synonym)|uniprotkb:RARP1(gene name synonym)|uniprotkb:RIAM(gene name synonym)|uniprotkb:APBB1-interacting protein 1(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 1(gene name synonym)|uniprotkb:Proline-rich protein 73(gene name synonym)|uniprotkb:Rap1-GTP-interacting adapter molecule(gene name synonym)|uniprotkb:Retinoic acid-responsive proline-rich protein 1(gene name synonym) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9100187|imex:IM-21827-368 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_061916.3|refseq:XP_006717514.1|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-6802952|ensembl:ENSG00000077420(gene)|ensembl:ENST00000376236(transcript)|go:"GO:0002291"(T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0030027"(lamellipodium)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0045785"(positive regulation of cell adhesion)|interpro:IPR000159(Ras-association)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR039664|interpro:IPR039665|rcsb pdb:2MWN|rcsb pdb:3ZDL|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|ensembl:ENST00000356785|ensembl:ENSP00000349237|ensembl:ENSP00000365411|uniprotkb:Q8IYL7(identity)|entrezgene/locuslink:54518(identity) psi-mi:"MI:0469"(intact) - - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:PLBPCQJk3g1jocBsOm6vYnsTRpU9606 intact-crc:0980AC7C0F5053AA|rigid:549I4UnyogsLVSvP/CELzOSRpuc false firefly luciferase protein tag:n-n("MI:1208")|sufficient binding region:1-487("MI:0442") tandem tag:n-n("MI:0677") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UQB8-6 uniprotkb:Q8IUH5 intact:EBI-9092016 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:q9uqb8-6(display_long)|uniprotkb:Fas ligand-associated factor 3(gene name synonym)|uniprotkb:Insulin receptor substrate p53/p58(gene name synonym)|uniprotkb:Insulin receptor substrate protein of 53 kDa(gene name synonym)|uniprotkb:BAIAP2(gene name)|psi-mi:BAIAP2(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9100208|imex:IM-21827-369 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-525456(isoform-parent)|uniprotkb:Q9UQB8-6(isoform-parent)|uniprotkb:Q9UQB8-6(identity)|entrezgene/locuslink:10458(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:n2iqdXaDCA6aLxGI9wl3/44N3ws9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:E5AB87898D37EBB3|rigid:ypBwBKFhpwngfRzmRPXEDAGu8nI false tandem tag:n-n("MI:0677") firefly luciferase protein tag:n-n("MI:1208")|sufficient binding region:1-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q15047-2 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9090795|ensembl:ENSP00000357958 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:q15047-2(display_long)|uniprotkb:SETDB1(gene name)|psi-mi:SETDB1(display_short)|uniprotkb:ERG-associated protein with SET domain(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 4(gene name synonym)|uniprotkb:KIAA0067(gene name synonym)|uniprotkb:KMT1E(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1E(gene name synonym)|uniprotkb:SET domain bifurcated 1(gene name synonym)|uniprotkb:ESET(gene name synonym) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9100274|imex:IM-21827-372 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) ensembl:ENSG00000143379(gene)|ensembl:ENST00000368962(transcript)|intact:EBI-79691(isoform-parent)|uniprotkb:Q15047-2(isoform-parent)|uniprotkb:Q15047-2(identity)|entrezgene/locuslink:9869(identity) psi-mi:"MI:0469"(intact) - isoform-comment:No experimental confirmation available. figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:ZRDrtJCxo50PTBfNTskZ+rLRXZM9606 intact-crc:26A2C5EEEDE8AB7C|rigid:lzmjFmvOlV+D30xFkHhiZqBFEac false sufficient binding region:1-257("MI:0442")|tandem tag:n-n("MI:0677") firefly luciferase protein tag:n-n("MI:1208") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UQB8-3 uniprotkb:Q8IUH5 intact:EBI-9091996|ensembl:ENSP00000458964 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:q9uqb8-3(display_long)|uniprotkb:Fas ligand-associated factor 3(gene name synonym)|uniprotkb:Insulin receptor substrate p53/p58(gene name synonym)|uniprotkb:Insulin receptor substrate protein of 53 kDa(gene name synonym)|uniprotkb:BAIAP2(gene name)|psi-mi:BAIAP2(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9100295|imex:IM-21827-373 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-525456(isoform-parent)|ensembl:ENSG00000175866(gene)|ensembl:ENST00000575712(transcript)|uniprotkb:Q9UQB8-3(isoform-parent)|uniprotkb:Q9UQB8-3(identity)|entrezgene/locuslink:10458(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:w60JYLTu20jqqHSqrbqjkPon5k49606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:2CDD09D47D35B4F6|rigid:/dt81vaIrPbukGSQptbg3LMAy5o false firefly luciferase protein tag:n-n("MI:1208") sufficient binding region:1-257("MI:0442")|tandem tag:n-n("MI:0677") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q08379 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9100250|imex:IM-21827-371 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|uniprotkb:Q08379(identity)|entrezgene/locuslink:2801(identity) psi-mi:"MI:0469"(intact) - - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606 intact-crc:63387E863D06A856|rigid:jUrGhSZ1tfwLFKP5a6r9EIHD9PM false tandem tag:n-n("MI:0677")|sufficient binding region:1-257("MI:0442") sufficient binding region:13-1002("MI:0442")|firefly luciferase protein tag:n-n("MI:1208") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O00161 uniprotkb:Q8IUH5 intact:EBI-745000|uniprotkb:O00162|uniprotkb:Q13602|uniprotkb:Q6IAE3|ensembl:ENSP00000249647 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:snp23_human(display_long)|uniprotkb:Vesicle-membrane fusion protein SNAP-23(gene name synonym)|uniprotkb:SNAP23(gene name)|psi-mi:SNAP23(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9100358|imex:IM-21827-376 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003816.2|refseq:NP_570710.1|ensembl:ENSG00000092531(gene)|ensembl:ENST00000249647(transcript)|go:"GO:0002553"(histamine secretion by mast cell)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006887"(exocytosis)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006903"(vesicle targeting)|go:"GO:0006906"(vesicle fusion)|go:"GO:0015031"(protein transport)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042581"(specific granule)|go:"GO:0042582"(azurophil granule)|go:"GO:0043005"(neuron projection)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0098793"(presynapse)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR000928(SNAP-25)|mint:O00161|rcsb pdb:1NHL|rcsb pdb:3ZUS|reactome:R-HSA-1445148|reactome:R-HSA-199992|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-1236974|uniprotkb:O00161(identity)|entrezgene/locuslink:8773(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:8ZcXbqhusSijGdekDMdkZA5DejY9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:3C00D732FC37E013|rigid:McBJa6jHMsQGoi4iaYvZ9HHfNCE false firefly luciferase protein tag:n-n("MI:1208") sufficient binding region:1-257("MI:0442")|tandem tag:n-n("MI:0677") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14847-2 uniprotkb:Q8IUH5 intact:EBI-9088686 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:q14847-2(display_long)|uniprotkb:MLN50(gene name synonym)|uniprotkb:Metastatic lymph node gene 50 protein(gene name synonym)|uniprotkb:LASP1(gene name)|psi-mi:LASP1(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9100337|imex:IM-21827-375 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-742828(isoform-parent)|uniprotkb:Q14847-2(isoform-parent)|uniprotkb:Q14847-2(identity)|entrezgene/locuslink:3927(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) isoform-comment:No experimental confirmation available. - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:uxyDFrkrlmWPmKK1RLEHRbysWj09606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:372B8480106F6BF9|rigid:n8d6vF31PncI6iKrjt6vnxM8mQo false firefly luciferase protein tag:n-n("MI:1208") sufficient binding region:1-257("MI:0442")|tandem tag:n-n("MI:0677") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96DA2 uniprotkb:Q8IUH5 intact:EBI-9089467|uniprotkb:Q5JT79|uniprotkb:Q8NEX3|ensembl:ENSP00000358466 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:rb39b_human(display_long)|uniprotkb:RAB39B(gene name)|psi-mi:RAB39B(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9100316|imex:IM-21827-374 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_741995.1|ensembl:ENSG00000155961(gene)|mint:Q96DA2|rcsb pdb:6S5F|reactome:R-HSA-8873719|reactome:R-HSA-8876198|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0043005"(neuron projection)|go:"GO:0050808"(synapse organization)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041818|ensembl:ENST00000369454(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031489"(myosin V binding)|go:"GO:0031982"(vesicle)|uniprotkb:Q96DA2(identity)|entrezgene/locuslink:116442(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:2lE8eIl2KSFMUz/cOKCRZmHO9oA9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:439A85A4D51E6FC9|rigid:07ZaWyzFNsIcfH4+i3nqvPipu2g false firefly luciferase protein tag:n-n("MI:1208") tandem tag:n-n("MI:0677")|sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IY31-3 uniprotkb:Q8IUH5 intact:EBI-9091197|ensembl:ENSP00000350570 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:q8iy31-3(display_long)|uniprotkb:IFT20(gene name)|psi-mi:IFT20(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9100379|imex:IM-21827-377 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-744203(isoform-parent)|ensembl:ENSG00000109083(gene)|ensembl:ENST00000357896(transcript)|uniprotkb:Q8IY31-3(isoform-parent)|uniprotkb:Q8IY31-3(identity)|entrezgene/locuslink:90410(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:pzW3oitgrBMPes/7NtSEKjfiDKU9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:91CA62EE2F7844A9|rigid:OXzn8w+g1rgEO/GCC1Jnf4s0R6g false firefly luciferase protein tag:n-n("MI:1208") tandem tag:n-n("MI:0677")|sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q96CV9-2 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9091423|ensembl:ENSP00000368027|ensembl:ENSP00000368040 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:q96cv9-2(display_long)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9100442|imex:IM-21827-380 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) intact:EBI-748974(isoform-parent)|ensembl:ENST00000378752(transcript)|ensembl:ENST00000378764(transcript)|ensembl:ENSG00000123240(gene)|uniprotkb:Q96CV9-2(isoform-parent)|uniprotkb:Q96CV9-2(identity)|entrezgene/locuslink:10133(identity) psi-mi:"MI:0469"(intact) - isoform-comment:No experimental confirmation available. figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2018/04/06 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:ygzEQkiDJwDAMUuFQuOWsSIqwAk9606 intact-crc:65E3F0AABE533AB4|rigid:QuIOv7mSpi10Z/MutH7/mS51ahU false sufficient binding region:1-257("MI:0442")|tandem tag:n-n("MI:0677") firefly luciferase protein tag:n-n("MI:1208") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7Z783 uniprotkb:Q8IUH5 intact:EBI-9088990|intact:EBI-12862946 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:q7z783_human(display_long) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9100421|imex:IM-21827-379 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007875(Sprouty)|interpro:IPR030780|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0005737"(cytoplasm)|go:"GO:0032587"(ruffle membrane)|go:"GO:0042127"(regulation of cell population proliferation)|uniprotkb:Q7Z783(identity)|entrezgene/locuslink:10253(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:e2aAamwhAPGI99/OO3G9dqo3u4w9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:FC1B80AA3221D302|rigid:f2OX5qb07HPqwqPVyX1gZOWEdo4 false firefly luciferase protein tag:n-n("MI:1208") tandem tag:n-n("MI:0677")|sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q9Y6W5 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-4290615|uniprotkb:O60794|uniprotkb:Q9UDY7|intact:EBI-28973998|ensembl:ENSP00000483313|uniprotkb:B4DZN0 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:wasf2_human(display_long)|uniprotkb:WASF2(gene name)|psi-mi:WASF2(display_short)|uniprotkb:WAVE2(gene name synonym)|uniprotkb:Protein WAVE-2(gene name synonym)|uniprotkb:Verprolin homology domain-containing protein 2(gene name synonym) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9100400|imex:IM-21827-378 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_008921.1|ensembl:ENST00000536657|ensembl:ENSP00000439883|ensembl:ENSP00000483313|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR028288|mint:Q9Y6W5|rcsb pdb:2A40|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|reactome:R-HSA-9664422|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|ensembl:ENSG00000158195(gene)|ensembl:ENST00000618852(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0001726"(ruffle)|go:"GO:0003779"(actin binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006897"(endocytosis)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0031209"(SCAR complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0072673"(lamellipodium morphogenesis)|refseq:NP_001188333.1|dip:DIP-41817N|uniprotkb:Q9Y6W5(identity)|entrezgene/locuslink:10163(identity) psi-mi:"MI:0469"(intact) - - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:lRPT4syjPdKz2JoqWQQm3xw4hWc9606 intact-crc:A3E72C4D9BCD0E0A|rigid:d+RW/+/MO8VbQ9+yFVJbF2sKAnM false sufficient binding region:1-257("MI:0442")|tandem tag:n-n("MI:0677") firefly luciferase protein tag:n-n("MI:1208") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UF11-4 uniprotkb:Q8IUH5 intact:EBI-9089825|ensembl:ENSP00000227214|ensembl:ENSP00000442616 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:q9uf11-4(display_long)|uniprotkb:EVT1(gene name synonym)|uniprotkb:Evectin-1(gene name synonym)|uniprotkb:KPL1(gene name synonym)|uniprotkb:PH domain-containing protein in retina 1(gene name synonym)|uniprotkb:PHR1(gene name synonym)|uniprotkb:PHRET1(gene name synonym)|uniprotkb:Pleckstrin homology domain retinal protein 1(gene name synonym)|uniprotkb:PLEKHB1(gene name)|psi-mi:PLEKHB1(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9100463|imex:IM-21827-381 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6447271(isoform-parent)|ensembl:ENSG00000021300(gene)|ensembl:ENST00000227214(transcript)|ensembl:ENST00000535129(transcript)|uniprotkb:Q9UF11-4(identity)|entrezgene/locuslink:58473(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:5RmF2rJLHJT3yM6ZP4+m7unTGNs9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:A8C861AB75BB0947|rigid:13anCpPEJYiB0tB5LzQ9S5O5LCI false firefly luciferase protein tag:n-n("MI:1208") sufficient binding region:1-257("MI:0442")|tandem tag:n-n("MI:0677") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7Z699 uniprotkb:Q8IUH5 intact:EBI-5235340|uniprotkb:B2RPJ8|uniprotkb:Q05D53|uniprotkb:Q8N256|ensembl:ENSP00000299084 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:spre1_human(display_long)|uniprotkb:SPRED1(gene name)|psi-mi:SPRED1(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9100484|imex:IM-21827-382 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_689807.1|ensembl:ENSG00000166068(gene)|ensembl:ENST00000299084(transcript)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0005173"(stem cell factor receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0060979"(vasculogenesis involved in coronary vascular morphogenesis)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:1902747"(negative regulation of lens fiber cell differentiation)|interpro:IPR000697(EVH1)|interpro:IPR007875(Sprouty)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023337|interpro:IPR041937|mint:Q7Z699|rcsb pdb:3SYX|rcsb pdb:6V65|rcsb pdb:6V6F|reactome:R-HSA-5658442|reactome:R-HSA-5658623|reactome:R-HSA-6802953|uniprotkb:Q7Z699(identity)|entrezgene/locuslink:161742(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:+jGnxx5TP0aeldLkqVGfO8uY2ko9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:B87BB8749C780603|rigid:0Gd7Ug3r/IvK1t7u7qhESghx+5E false firefly luciferase protein tag:n-n("MI:1208") sufficient binding region:1-257("MI:0442")|tandem tag:n-n("MI:0677") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:O60259 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-3915857|uniprotkb:Q5V9X1|uniprotkb:Q5V9X2|uniprotkb:Q9UQ47|uniprotkb:Q9HCB3|uniprotkb:Q9NR69|uniprotkb:Q8IW69|uniprotkb:Q9UIL9|uniprotkb:Q9NR68|ensembl:ENSP00000472016 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:klk8_human(display_long)|uniprotkb:KLK8(gene name)|psi-mi:KLK8(display_short)|uniprotkb:NRPN(gene name synonym)|uniprotkb:PRSS19(gene name synonym)|uniprotkb:TADG14(gene name synonym)|uniprotkb:Neuropsin(gene name synonym)|uniprotkb:Ovasin(gene name synonym)|uniprotkb:Serine protease 19(gene name synonym)|uniprotkb:Serine protease TADG-14(gene name synonym)|uniprotkb:Tumor-associated differentially expressed gene 14 protein(gene name synonym)|uniprotkb:UNQ283/PRO322(orf name) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9100505|imex:IM-21827-383 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_009127.1|refseq:NP_653088.1|refseq:NP_653089.1|refseq:NP_653090.1|refseq:NP_001268360.1|ensembl:ENSG00000129455(gene)|ensembl:ENST00000600767(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0007613"(memory)|go:"GO:0008219"(cell death)|go:"GO:0009611"(response to wounding)|go:"GO:0030141"(secretory granule)|go:"GO:0031642"(negative regulation of myelination)|go:"GO:0043616"(keratinocyte proliferation)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0050808"(synapse organization)|go:"GO:0097180"(serine protease inhibitor complex)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504|rcsb pdb:5MS3|rcsb pdb:5MS4|reactome:R-HSA-6809371|uniprotkb:O60259(identity)|entrezgene/locuslink:11202(identity) psi-mi:"MI:0469"(intact) - - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:uWjD9cViyVX9pl6mWgGUT6SF14s9606 intact-crc:4BBA2C819B45CE12|rigid:JAQqC2992j3L6890HJaSYJkoqRE false sufficient binding region:1-257("MI:0442")|tandem tag:n-n("MI:0677") firefly luciferase protein tag:n-n("MI:1208") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96GN5-2 uniprotkb:Q8IUH5 intact:EBI-9091443 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:q96gn5-2(display_long)|uniprotkb:HR1(gene name synonym)|uniprotkb:JPO2(gene name synonym)|uniprotkb:Protein JPO2(gene name synonym)|uniprotkb:R1(gene name synonym)|uniprotkb:Transcription factor RAM2(gene name synonym)|uniprotkb:Variant B(isoform synonym)|uniprotkb:CDCA7L(gene name)|psi-mi:CDCA7L(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9100568|imex:IM-21827-386 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-5278764(isoform-parent)|uniprotkb:Q96GN5-2(isoform-parent)|uniprotkb:Q96GN5-2(identity)|entrezgene/locuslink:8701(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:wcrQtkogtBLIPTSe1iz4xoeshSY9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:0D4DF2BE5BC5449F|rigid:NsCPBJbnJI4aKJ3BUc2boz1yA/E false firefly luciferase protein tag:n-n("MI:1208") tandem tag:n-n("MI:0677")|sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P51674 uniprotkb:Q8IUH5 intact:EBI-7187133|ensembl:ENSP00000280187|ensembl:ENSP00000377268|intact:UNK-5379643|uniprotkb:Q92602|uniprotkb:E9PHI5|uniprotkb:B7Z642 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:gpm6a_human(display_long)|uniprotkb:GPM6A(gene name)|psi-mi:GPM6A(display_short)|uniprotkb:M6A(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9100547|imex:IM-21827-385 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000150625(gene)|ensembl:ENST00000280187(transcript)|ensembl:ENST00000393658(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003407"(neural retina development)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007416"(synapse assembly)|go:"GO:0009617"(response to bacterium)|go:"GO:0030175"(filopodium)|go:"GO:0031175"(neuron projection development)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044295"(axonal growth cone)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR001614(Myelin proteolipid protein PLP)|interpro:IPR018237|refseq:NP_001248377.1|refseq:NP_963885.1|refseq:NP_005268.1|refseq:NP_963886.1|uniprotkb:P51674(identity)|entrezgene/locuslink:2823(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) comment:mint|comment:homomint - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:6h/p/+l8WRhJ9HsGcbxleQuDtSo9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:1A5C734ECD787900|rigid:LqEIwgfaRcyLZlpgZ3CzWDM5ChA false firefly luciferase protein tag:n-n("MI:1208") sufficient binding region:1-257("MI:0442")|tandem tag:n-n("MI:0677") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:O15530-4 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9087775|ensembl:ENSP00000268673 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:o15530-4(display_long)|uniprotkb:PDK1(gene name synonym)|uniprotkb:PDPK1(gene name)|psi-mi:PDPK1(display_short) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9100526|imex:IM-21827-384 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) intact:EBI-717097(isoform-parent)|ensembl:ENSG00000140992(gene)|ensembl:ENST00000268673(transcript)|uniprotkb:O15530-4(isoform-parent)|uniprotkb:O15530-4(identity)|entrezgene/locuslink:5170(identity) psi-mi:"MI:0469"(intact) - - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:xpGOPsJyFONnxfu4HaGOV4BLjX09606 intact-crc:D9513DA9AA670DD7|rigid:x3pKmPRr055h9hs4u1wbIgXavzo false sufficient binding region:1-257("MI:0442")|tandem tag:n-n("MI:0677") firefly luciferase protein tag:n-n("MI:1208") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:P15336 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-1170906|uniprotkb:Q13000|uniprotkb:Q4ZFU9|uniprotkb:Q53RY2|uniprotkb:A1L3Z2|uniprotkb:D3DPE9|uniprotkb:Q8TAR1|uniprotkb:A4D7U4|uniprotkb:G8JLM5|uniprotkb:Q3B7B7|uniprotkb:A4D7U5|uniprotkb:A4D7V1|uniprotkb:Q96JT8|intact:EBI-28988937|ensembl:ENSP00000264110|ensembl:ENSP00000376327 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:atf2_human(display_long)|uniprotkb:ATF2(gene name)|psi-mi:ATF2(display_short)|uniprotkb:CREB2(gene name synonym)|uniprotkb:CREBP1(gene name synonym)|uniprotkb:Activating transcription factor 2(gene name synonym)|uniprotkb:cAMP response element-binding protein CRE-BP1(gene name synonym)|uniprotkb:HB16(gene name synonym)|uniprotkb:Cyclic AMP-responsive element-binding protein 2(gene name synonym) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9100610|imex:IM-21827-388 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_001243019.1|refseq:NP_001243020.1|refseq:NP_001871.2|refseq:NP_001243023.1|ensembl:ENST00000345739|ensembl:ENSP00000340576|ensembl:ENSP00000376327|ensembl:ENST00000409499|ensembl:ENSP00000386282|ensembl:ENST00000409635|ensembl:ENSP00000387093|ensembl:ENST00000409833|ensembl:ENSP00000386526|ensembl:ENST00000426833|ensembl:ENSP00000407911|ensembl:ENSP00000264110|refseq:NP_001243021.1|refseq:NP_001243022.1|ensembl:ENSG00000115966(gene)|ensembl:ENST00000264110(transcript)|ensembl:ENST00000392544(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0009414"(response to water deprivation)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0032915"(positive regulation of transforming growth factor beta2 production)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0110024"(positive regulation of cardiac muscle myoblast proliferation)|go:"GO:1902110"(positive regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1902562"(H4 histone acetyltransferase complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR016378(Transcription factor, cyclic AMP-dependent)|interpro:IPR029836|interpro:IPR036236|mint:P15336|rcsb pdb:1BHI|rcsb pdb:1T2K|rcsb pdb:4H36|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|rcsb pdb:6ZQS|rcsb pdb:6ZR5|reactome:R-HSA-2151201|reactome:R-HSA-3214847|reactome:R-HSA-400253|reactome:R-HSA-450341|reactome:R-HSA-6796648|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9031628|reactome:R-HSA-9633012|reactome:R-HSA-9707616|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043969"(histone H2B acetylation)|go:"GO:0044013"(H2B histone acetyltransferase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060612"(adipose tissue development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097186"(amelogenesis)|dip:DIP-632N|uniprotkb:P15336(identity)|entrezgene/locuslink:1386(identity) psi-mi:"MI:0469"(intact) - - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:9krWq+A9Y3xvkInqyJnJs1g9tfc9606 intact-crc:E132ECCE2F6906FB|rigid:WMf14R/I1ByvF4hbyKrR7XBPNqQ false sufficient binding region:1-487("MI:0442")|tandem tag:n-n("MI:0677") firefly luciferase protein tag:n-n("MI:1208")|sufficient binding region:1-209("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q9UHY8 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-396453|uniprotkb:Q76LN0|uniprotkb:Q99690|uniprotkb:Q5EBN3|intact:EBI-28984869|ensembl:ENSP00000385112 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:fez2_human(display_long)|uniprotkb:FEZ2(gene name)|psi-mi:FEZ2(display_short)|uniprotkb:Zygin-2(gene name synonym)|uniprotkb:Zygin II(gene name synonym) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9100634|imex:IM-21827-389 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_001036013.1|refseq:NP_005093.2|ensembl:ENST00000379245|ensembl:ENSP00000368547|ensembl:ENSP00000385112|ensembl:ENSG00000171055(gene)|ensembl:ENST00000405912(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0030424"(axon)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR011680(FEZ-like)|interpro:IPR015641(Fasciculation and elongation protein zeta 2)|mint:Q9UHY8|uniprotkb:Q9UHY8(identity)|entrezgene/locuslink:9637(identity) psi-mi:"MI:0469"(intact) - - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:n5uH+vdgrrvmI+PYkcMUEnAzxwE9606 intact-crc:AF03F76DF7B629E9|rigid:GO+MMpsXWNWtmeuSVCaqXwlLXpU false tandem tag:n-n("MI:0677")|sufficient binding region:1-487("MI:0442") firefly luciferase protein tag:n-n("MI:1208") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:P48730-2 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9087876|ensembl:ENSP00000376146 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:p48730-2(display_long)|uniprotkb:HCKID(gene name synonym)|uniprotkb:Tau-protein kinase CSNK1D(gene name synonym)|uniprotkb:CSNK1D(gene name)|psi-mi:CSNK1D(display_short) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9100589|imex:IM-21827-387 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) intact:EBI-751621(isoform-parent)|ensembl:ENSG00000141551(gene)|ensembl:ENST00000392334(transcript)|uniprotkb:P48730-2(isoform-parent)|uniprotkb:P48730-2(identity)|entrezgene/locuslink:1453(identity) psi-mi:"MI:0469"(intact) - - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:DKYeQTtdg+u5Gm9wscDkiTs7Blg9606 intact-crc:FDADE3F575548707|rigid:yI9cncQsphvllXDDNHnH3oz7OZ8 false sufficient binding region:1-487("MI:0442")|tandem tag:n-n("MI:0677") firefly luciferase protein tag:n-n("MI:1208") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:P60228 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-347740|uniprotkb:O43902|uniprotkb:Q64058|uniprotkb:Q64059|uniprotkb:Q64252|uniprotkb:Q8WVK4|intact:EBI-1237448|uniprotkb:Q6FG33|ensembl:ENSP00000220849 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:eif3e_human(display_long)|uniprotkb:EIF3E(gene name)|psi-mi:EIF3E(display_short)|uniprotkb:INT6(gene name synonym)|uniprotkb:EIF3S6(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 6(gene name synonym)|uniprotkb:eIF-3 p48(gene name synonym)|uniprotkb:Viral integration site protein INT-6 homolog(gene name synonym) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9100655|imex:IM-21827-390 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_001559.1|ensembl:ENSG00000104408(gene)|ensembl:ENST00000220849(transcript)|dip:DIP-32691N|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0016605"(PML body)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071540"(eukaryotic translation initiation factor 3 complex, eIF3e)|go:"GO:1902416"(positive regulation of mRNA binding)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR016650(Translation initiation factor 3, subunit 6, eukaryotic)|interpro:IPR019010|interpro:IPR036390|mint:P60228|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6FEC|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|uniprotkb:P60228(identity)|entrezgene/locuslink:3646(identity) psi-mi:"MI:0469"(intact) - - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:s09LicCa0mb9WwO7esZvVdvUonY9606 intact-crc:E016AF951FBDF542|rigid:ETHBbAOKTOtXo+M7ObTltuArKpc false sufficient binding region:1-487("MI:0442")|tandem tag:n-n("MI:0677") firefly luciferase protein tag:n-n("MI:1208") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O15530-4 uniprotkb:Q8IUH5 intact:EBI-9087775|ensembl:ENSP00000268673 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:o15530-4(display_long)|uniprotkb:PDK1(gene name synonym)|uniprotkb:PDPK1(gene name)|psi-mi:PDPK1(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9100697|imex:IM-21827-392 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-717097(isoform-parent)|ensembl:ENSG00000140992(gene)|ensembl:ENST00000268673(transcript)|uniprotkb:O15530-4(isoform-parent)|uniprotkb:O15530-4(identity)|entrezgene/locuslink:5170(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:xpGOPsJyFONnxfu4HaGOV4BLjX09606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:90CAD7D002C74AF0|rigid:x3pKmPRr055h9hs4u1wbIgXavzo false tandem tag:n-n("MI:0677") firefly luciferase protein tag:n-n("MI:1208")|sufficient binding region:64-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O00161 uniprotkb:Q8IUH5 intact:EBI-745000|uniprotkb:O00162|uniprotkb:Q13602|uniprotkb:Q6IAE3|ensembl:ENSP00000249647 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:snp23_human(display_long)|uniprotkb:Vesicle-membrane fusion protein SNAP-23(gene name synonym)|uniprotkb:SNAP23(gene name)|psi-mi:SNAP23(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9100676|imex:IM-21827-391 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003816.2|refseq:NP_570710.1|ensembl:ENSG00000092531(gene)|ensembl:ENST00000249647(transcript)|go:"GO:0002553"(histamine secretion by mast cell)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006887"(exocytosis)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006903"(vesicle targeting)|go:"GO:0006906"(vesicle fusion)|go:"GO:0015031"(protein transport)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042581"(specific granule)|go:"GO:0042582"(azurophil granule)|go:"GO:0043005"(neuron projection)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0098793"(presynapse)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR000928(SNAP-25)|mint:O00161|rcsb pdb:1NHL|rcsb pdb:3ZUS|reactome:R-HSA-1445148|reactome:R-HSA-199992|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-1236974|uniprotkb:O00161(identity)|entrezgene/locuslink:8773(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:8ZcXbqhusSijGdekDMdkZA5DejY9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:62243E77BCC2B74F|rigid:McBJa6jHMsQGoi4iaYvZ9HHfNCE false tandem tag:n-n("MI:0677") sufficient binding region:1-257("MI:0442")|firefly luciferase protein tag:n-n("MI:1208") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:P49840 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-1044067|uniprotkb:O14959|ensembl:ENSP00000222330|ensembl:ENSP00000412663 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:gsk3a_human(display_long)|uniprotkb:GSK3A(gene name)|psi-mi:GSK3A(display_short)|uniprotkb:Serine/threonine-protein kinase GSK3A(gene name synonym) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9100763|imex:IM-21827-395 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) ensembl:ENSG00000105723(gene)|ensembl:ENST00000222330(transcript)|ensembl:ENST00000453535(transcript)|go:"GO:0003073"(regulation of systemic arterial blood pressure)|go:"GO:0003214"(cardiac left ventricle morphogenesis)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007212"(dopamine receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007568"(aging)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010905"(negative regulation of UDP-glucose catabolic process)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016477"(cell migration)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0036016"(cellular response to interleukin-3)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044027"(hypermethylation of CpG island)|go:"GO:0045719"(negative regulation of glycogen biosynthetic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0048156"(tau protein binding)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071879"(positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097440"(apical dendrite)|go:"GO:0098794"(postsynapse)|go:"GO:0106071"(positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1904227"(negative regulation of glycogen synthase activity, transferring glucose-1-phosphate)|go:"GO:1990635"(proximal dendrite)|go:"GO:2000077"(negative regulation of type B pancreatic cell development)|go:"GO:2000171"(negative regulation of dendrite development)|go:"GO:2000466"("negative regulation of glycogen (starch) synthase activity")|go:"GO:2000467"("positive regulation of glycogen (starch) synthase activity")|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR039192|mint:P49840|rcsb pdb:2DFM|reactome:R-HSA-198323|go:"GO:1901030"(positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|reactome:R-HSA-381038|reactome:R-HSA-5674400|reactome:R-HSA-9635465|reactome:R-HSA-9682706|reactome:R-HSA-9694686|refseq:NP_063937.2|uniprotkb:P49840(identity)|entrezgene/locuslink:2931(identity) psi-mi:"MI:0469"(intact) - - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:CTNNFDhWycUTAOEW/KD2UXu0U7Y9606 intact-crc:CFE8D00569E39DDD|rigid:FCirhlNcS2O93Jpq4kb812s1oy0 false sufficient binding region:64-257("MI:0442")|firefly luciferase protein tag:n-n("MI:1208") tandem tag:n-n("MI:0677") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:O60259 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-3915857|uniprotkb:Q5V9X1|uniprotkb:Q5V9X2|uniprotkb:Q9UQ47|uniprotkb:Q9HCB3|uniprotkb:Q9NR69|uniprotkb:Q8IW69|uniprotkb:Q9UIL9|uniprotkb:Q9NR68|ensembl:ENSP00000472016 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:klk8_human(display_long)|uniprotkb:KLK8(gene name)|psi-mi:KLK8(display_short)|uniprotkb:NRPN(gene name synonym)|uniprotkb:PRSS19(gene name synonym)|uniprotkb:TADG14(gene name synonym)|uniprotkb:Neuropsin(gene name synonym)|uniprotkb:Ovasin(gene name synonym)|uniprotkb:Serine protease 19(gene name synonym)|uniprotkb:Serine protease TADG-14(gene name synonym)|uniprotkb:Tumor-associated differentially expressed gene 14 protein(gene name synonym)|uniprotkb:UNQ283/PRO322(orf name) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9100718|imex:IM-21827-393 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_009127.1|refseq:NP_653088.1|refseq:NP_653089.1|refseq:NP_653090.1|refseq:NP_001268360.1|ensembl:ENSG00000129455(gene)|ensembl:ENST00000600767(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0007613"(memory)|go:"GO:0008219"(cell death)|go:"GO:0009611"(response to wounding)|go:"GO:0030141"(secretory granule)|go:"GO:0031642"(negative regulation of myelination)|go:"GO:0043616"(keratinocyte proliferation)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0050808"(synapse organization)|go:"GO:0097180"(serine protease inhibitor complex)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504|rcsb pdb:5MS3|rcsb pdb:5MS4|reactome:R-HSA-6809371|uniprotkb:O60259(identity)|entrezgene/locuslink:11202(identity) psi-mi:"MI:0469"(intact) - - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:uWjD9cViyVX9pl6mWgGUT6SF14s9606 intact-crc:C7CA16D387659F75|rigid:JAQqC2992j3L6890HJaSYJkoqRE false sufficient binding region:64-257("MI:0442")|firefly luciferase protein tag:n-n("MI:1208") tandem tag:n-n("MI:0677") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:P15336 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-1170906|uniprotkb:Q13000|uniprotkb:Q4ZFU9|uniprotkb:Q53RY2|uniprotkb:A1L3Z2|uniprotkb:D3DPE9|uniprotkb:Q8TAR1|uniprotkb:A4D7U4|uniprotkb:G8JLM5|uniprotkb:Q3B7B7|uniprotkb:A4D7U5|uniprotkb:A4D7V1|uniprotkb:Q96JT8|intact:EBI-28988937|ensembl:ENSP00000264110|ensembl:ENSP00000376327 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:atf2_human(display_long)|uniprotkb:ATF2(gene name)|psi-mi:ATF2(display_short)|uniprotkb:CREB2(gene name synonym)|uniprotkb:CREBP1(gene name synonym)|uniprotkb:Activating transcription factor 2(gene name synonym)|uniprotkb:cAMP response element-binding protein CRE-BP1(gene name synonym)|uniprotkb:HB16(gene name synonym)|uniprotkb:Cyclic AMP-responsive element-binding protein 2(gene name synonym) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9100739|imex:IM-21827-394 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_001243019.1|refseq:NP_001243020.1|refseq:NP_001871.2|refseq:NP_001243023.1|ensembl:ENST00000345739|ensembl:ENSP00000340576|ensembl:ENSP00000376327|ensembl:ENST00000409499|ensembl:ENSP00000386282|ensembl:ENST00000409635|ensembl:ENSP00000387093|ensembl:ENST00000409833|ensembl:ENSP00000386526|ensembl:ENST00000426833|ensembl:ENSP00000407911|ensembl:ENSP00000264110|refseq:NP_001243021.1|refseq:NP_001243022.1|ensembl:ENSG00000115966(gene)|ensembl:ENST00000264110(transcript)|ensembl:ENST00000392544(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0009414"(response to water deprivation)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0032915"(positive regulation of transforming growth factor beta2 production)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0110024"(positive regulation of cardiac muscle myoblast proliferation)|go:"GO:1902110"(positive regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1902562"(H4 histone acetyltransferase complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR016378(Transcription factor, cyclic AMP-dependent)|interpro:IPR029836|interpro:IPR036236|mint:P15336|rcsb pdb:1BHI|rcsb pdb:1T2K|rcsb pdb:4H36|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|rcsb pdb:6ZQS|rcsb pdb:6ZR5|reactome:R-HSA-2151201|reactome:R-HSA-3214847|reactome:R-HSA-400253|reactome:R-HSA-450341|reactome:R-HSA-6796648|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9031628|reactome:R-HSA-9633012|reactome:R-HSA-9707616|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043969"(histone H2B acetylation)|go:"GO:0044013"(H2B histone acetyltransferase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060612"(adipose tissue development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097186"(amelogenesis)|dip:DIP-632N|uniprotkb:P15336(identity)|entrezgene/locuslink:1386(identity) psi-mi:"MI:0469"(intact) - - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:9krWq+A9Y3xvkInqyJnJs1g9tfc9606 intact-crc:FE0160916C543EAB|rigid:WMf14R/I1ByvF4hbyKrR7XBPNqQ false firefly luciferase protein tag:n-n("MI:1208")|sufficient binding region:1-257("MI:0442") sufficient binding region:1-209("MI:0442")|tandem tag:n-n("MI:0677") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P51674 uniprotkb:Q8IUH5 intact:EBI-7187133|ensembl:ENSP00000280187|ensembl:ENSP00000377268|intact:UNK-5379643|uniprotkb:Q92602|uniprotkb:E9PHI5|uniprotkb:B7Z642 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:gpm6a_human(display_long)|uniprotkb:GPM6A(gene name)|psi-mi:GPM6A(display_short)|uniprotkb:M6A(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9100784|imex:IM-21827-396 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000150625(gene)|ensembl:ENST00000280187(transcript)|ensembl:ENST00000393658(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003407"(neural retina development)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007416"(synapse assembly)|go:"GO:0009617"(response to bacterium)|go:"GO:0030175"(filopodium)|go:"GO:0031175"(neuron projection development)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044295"(axonal growth cone)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR001614(Myelin proteolipid protein PLP)|interpro:IPR018237|refseq:NP_001248377.1|refseq:NP_963885.1|refseq:NP_005268.1|refseq:NP_963886.1|uniprotkb:P51674(identity)|entrezgene/locuslink:2823(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) comment:mint|comment:homomint - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:6h/p/+l8WRhJ9HsGcbxleQuDtSo9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:4FF147C96807A4CC|rigid:LqEIwgfaRcyLZlpgZ3CzWDM5ChA false tandem tag:n-n("MI:0677") firefly luciferase protein tag:n-n("MI:1208")|sufficient binding region:64-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:P68104 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9100805|imex:IM-21827-397 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1|entrezgene/locuslink:1915(identity)|uniprotkb:P68104(identity) psi-mi:"MI:0469"(intact) - - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606 intact-crc:81DECC20677617DC|rigid:BpLDa3GC7SU2Cicw3qWq0PqCzbA false firefly luciferase protein tag:n-n("MI:1208")|sufficient binding region:1-257("MI:0442") tandem tag:n-n("MI:0677") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q13188 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-992580|uniprotkb:Q15445|uniprotkb:Q15801|uniprotkb:Q96FM6|uniprotkb:A8K722|ensembl:ENSP00000390500|uniprotkb:B3KYA7 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:stk3_human(display_long)|uniprotkb:STE20-like kinase MST2(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Krs-1(gene name synonym)|uniprotkb:STK3(gene name)|psi-mi:STK3(display_short)|uniprotkb:MST2(gene name synonym)|uniprotkb:KRS1(gene name synonym) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9100826|imex:IM-21827-398 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_001243241.1|refseq:NP_006272.2|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011524(SARAH)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR024205|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|interpro:IPR036674|mint:Q13188|rcsb pdb:3WWS|rcsb pdb:4HKD|rcsb pdb:4L0N|rcsb pdb:4LG4|rcsb pdb:4LGD|rcsb pdb:4OH9|rcsb pdb:5BRM|rcsb pdb:5DH3|rcsb pdb:6AO5|rcsb pdb:6AR2|reactome:R-HSA-2028269|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060215"(primitive hemopoiesis)|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0060800"(regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0106311"|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|ensembl:ENSG00000104375(gene)|ensembl:ENST00000419617(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001841"(neural tube formation)|go:"GO:0003157"(endocardium development)|dip:DIP-36128N|uniprotkb:Q13188(identity)|entrezgene/locuslink:6788(identity) psi-mi:"MI:0469"(intact) - - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:slrC4Ax6263chBC1DJygdoExuCc9606 intact-crc:BBC7435C33CC6A07|rigid:wGKRhUvCv/bMp6miwFoJLZNKPpY false firefly luciferase protein tag:n-n("MI:1208")|sufficient binding region:64-257("MI:0442") tandem tag:n-n("MI:0677") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q8NFA0 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-2511075|ensembl:ENSP00000300896|intact:EBI-9091112|uniprotkb:Q7Z5T3|uniprotkb:Q9Y591|uniprotkb:Q9BX85 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:ubp32_human(display_long)|uniprotkb:USP32(gene name)|psi-mi:USP32(display_short)|uniprotkb:USP10(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 32(gene name synonym)|uniprotkb:Deubiquitinating enzyme 32(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-60(gene name synonym)|uniprotkb:Ubiquitin thioesterase 32(gene name synonym) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9100889|imex:IM-21827-401 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) ensembl:ENSG00000170832(gene)|ensembl:ENST00000300896(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016579"(protein deubiquitination)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR018200|interpro:IPR018247|interpro:IPR028889|interpro:IPR035927|interpro:IPR038765|interpro:IPR011992(EF-Hand type)|refseq:NP_115971.2|dip:DIP-53613N|uniprotkb:Q7Z5T3(identity)|entrezgene/locuslink:84669(identity) psi-mi:"MI:0469"(intact) - - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:DOnkgvUHy/ldOL9DCSP8PJppAY09606 intact-crc:40A7300B0D0E348F|rigid:l4POG5nLRhAIEVTx5SD6NNBg4P0 false sufficient binding region:64-257("MI:0442")|firefly luciferase protein tag:n-n("MI:1208") tandem tag:n-n("MI:0677") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q15047-2 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9090795|ensembl:ENSP00000357958 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:q15047-2(display_long)|uniprotkb:SETDB1(gene name)|psi-mi:SETDB1(display_short)|uniprotkb:ERG-associated protein with SET domain(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 4(gene name synonym)|uniprotkb:KIAA0067(gene name synonym)|uniprotkb:KMT1E(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1E(gene name synonym)|uniprotkb:SET domain bifurcated 1(gene name synonym)|uniprotkb:ESET(gene name synonym) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9100868|imex:IM-21827-400 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) ensembl:ENSG00000143379(gene)|ensembl:ENST00000368962(transcript)|intact:EBI-79691(isoform-parent)|uniprotkb:Q15047-2(isoform-parent)|uniprotkb:Q15047-2(identity)|entrezgene/locuslink:9869(identity) psi-mi:"MI:0469"(intact) - isoform-comment:No experimental confirmation available. figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:ZRDrtJCxo50PTBfNTskZ+rLRXZM9606 intact-crc:8CB2452C90CB855C|rigid:lzmjFmvOlV+D30xFkHhiZqBFEac false sufficient binding region:1-257("MI:0442")|firefly luciferase protein tag:n-n("MI:1208") tandem tag:n-n("MI:0677") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q14847-2 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9088686 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:q14847-2(display_long)|uniprotkb:MLN50(gene name synonym)|uniprotkb:Metastatic lymph node gene 50 protein(gene name synonym)|uniprotkb:LASP1(gene name)|psi-mi:LASP1(display_short) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9100847|imex:IM-21827-399 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) intact:EBI-742828(isoform-parent)|uniprotkb:Q14847-2(isoform-parent)|uniprotkb:Q14847-2(identity)|entrezgene/locuslink:3927(identity) psi-mi:"MI:0469"(intact) - isoform-comment:No experimental confirmation available. figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:uxyDFrkrlmWPmKK1RLEHRbysWj09606 intact-crc:DD18D217A0C531F9|rigid:n8d6vF31PncI6iKrjt6vnxM8mQo false sufficient binding region:1-257("MI:0442")|firefly luciferase protein tag:n-n("MI:1208") tandem tag:n-n("MI:0677") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7Z783 uniprotkb:Q8IUH5 intact:EBI-9088990|intact:EBI-12862946 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:q7z783_human(display_long) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9100931|imex:IM-21827-403 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007875(Sprouty)|interpro:IPR030780|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0005737"(cytoplasm)|go:"GO:0032587"(ruffle membrane)|go:"GO:0042127"(regulation of cell population proliferation)|uniprotkb:Q7Z783(identity)|entrezgene/locuslink:10253(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:e2aAamwhAPGI99/OO3G9dqo3u4w9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:59366A19B6E829BF|rigid:f2OX5qb07HPqwqPVyX1gZOWEdo4 false tandem tag:n-n("MI:0677") firefly luciferase protein tag:n-n("MI:1208")|sufficient binding region:64-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q8IY31-3 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9091197|ensembl:ENSP00000350570 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:q8iy31-3(display_long)|uniprotkb:IFT20(gene name)|psi-mi:IFT20(display_short) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9100952|imex:IM-21827-404 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) intact:EBI-744203(isoform-parent)|ensembl:ENSG00000109083(gene)|ensembl:ENST00000357896(transcript)|uniprotkb:Q8IY31-3(isoform-parent)|uniprotkb:Q8IY31-3(identity)|entrezgene/locuslink:90410(identity) psi-mi:"MI:0469"(intact) - - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:pzW3oitgrBMPes/7NtSEKjfiDKU9606 intact-crc:BCD1AAFBEFF8CFE1|rigid:OXzn8w+g1rgEO/GCC1Jnf4s0R6g false sufficient binding region:1-257("MI:0442")|firefly luciferase protein tag:n-n("MI:1208") tandem tag:n-n("MI:0677") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q7Z699 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-5235340|uniprotkb:B2RPJ8|uniprotkb:Q05D53|uniprotkb:Q8N256|ensembl:ENSP00000299084 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:spre1_human(display_long)|uniprotkb:SPRED1(gene name)|psi-mi:SPRED1(display_short) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9100910|imex:IM-21827-402 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_689807.1|ensembl:ENSG00000166068(gene)|ensembl:ENST00000299084(transcript)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0005173"(stem cell factor receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0060979"(vasculogenesis involved in coronary vascular morphogenesis)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:1902747"(negative regulation of lens fiber cell differentiation)|interpro:IPR000697(EVH1)|interpro:IPR007875(Sprouty)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023337|interpro:IPR041937|mint:Q7Z699|rcsb pdb:3SYX|rcsb pdb:6V65|rcsb pdb:6V6F|reactome:R-HSA-5658442|reactome:R-HSA-5658623|reactome:R-HSA-6802953|uniprotkb:Q7Z699(identity)|entrezgene/locuslink:161742(identity) psi-mi:"MI:0469"(intact) - - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:+jGnxx5TP0aeldLkqVGfO8uY2ko9606 intact-crc:E5218BDCB862950C|rigid:0Gd7Ug3r/IvK1t7u7qhESghx+5E false firefly luciferase protein tag:n-n("MI:1208")|sufficient binding region:64-257("MI:0442") tandem tag:n-n("MI:0677") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96DA2 uniprotkb:Q8IUH5 intact:EBI-9089467|uniprotkb:Q5JT79|uniprotkb:Q8NEX3|ensembl:ENSP00000358466 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:rb39b_human(display_long)|uniprotkb:RAB39B(gene name)|psi-mi:RAB39B(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9100973|imex:IM-21827-405 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_741995.1|ensembl:ENSG00000155961(gene)|mint:Q96DA2|rcsb pdb:6S5F|reactome:R-HSA-8873719|reactome:R-HSA-8876198|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0043005"(neuron projection)|go:"GO:0050808"(synapse organization)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041818|ensembl:ENST00000369454(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031489"(myosin V binding)|go:"GO:0031982"(vesicle)|uniprotkb:Q96DA2(identity)|entrezgene/locuslink:116442(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:2lE8eIl2KSFMUz/cOKCRZmHO9oA9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:094594A461527B70|rigid:07ZaWyzFNsIcfH4+i3nqvPipu2g false tandem tag:n-n("MI:0677") firefly luciferase protein tag:n-n("MI:1208")|sufficient binding region:64-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q9C004 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-354861|uniprotkb:Q6QIX2|uniprotkb:A4FVB3|uniprotkb:Q9C003|uniprotkb:A4FVB2|ensembl:ENSP00000399468 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:spy4_human(display_long)|uniprotkb:SPRY4(gene name)|psi-mi:SPRY4(display_short) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9100994|imex:IM-21827-406 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_001120968.1|refseq:NP_112226.2|refseq:NP_001280218.1|refseq:NP_001280219.1|refseq:XP_011535987.1|refseq:XP_016865399.1|ensembl:ENSG00000187678(gene)|ensembl:ENST00000434127(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0032587"(ruffle membrane)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048513"(animal organ development)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR007875(Sprouty)|interpro:IPR030790|mint:Q9C004|rcsb pdb:3BUN|uniprotkb:Q9C004(identity)|entrezgene/locuslink:81848(identity) psi-mi:"MI:0469"(intact) - - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:NjkIqofg1Fl1PXj8FXVFz10JOUg9606 intact-crc:DC68C0A64B795FF9|rigid:h++nln/HV6t7YeW22DNyvvtlQH4 false sufficient binding region:1-257("MI:0442")|firefly luciferase protein tag:n-n("MI:1208") tandem tag:n-n("MI:0677") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q9UF11-4 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9089825|ensembl:ENSP00000227214|ensembl:ENSP00000442616 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:q9uf11-4(display_long)|uniprotkb:EVT1(gene name synonym)|uniprotkb:Evectin-1(gene name synonym)|uniprotkb:KPL1(gene name synonym)|uniprotkb:PH domain-containing protein in retina 1(gene name synonym)|uniprotkb:PHR1(gene name synonym)|uniprotkb:PHRET1(gene name synonym)|uniprotkb:Pleckstrin homology domain retinal protein 1(gene name synonym)|uniprotkb:PLEKHB1(gene name)|psi-mi:PLEKHB1(display_short) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9101057|imex:IM-21827-409 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) intact:EBI-6447271(isoform-parent)|ensembl:ENSG00000021300(gene)|ensembl:ENST00000227214(transcript)|ensembl:ENST00000535129(transcript)|uniprotkb:Q9UF11-4(identity)|entrezgene/locuslink:58473(identity) psi-mi:"MI:0469"(intact) - - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:5RmF2rJLHJT3yM6ZP4+m7unTGNs9606 intact-crc:663DF8AFB43CB9E8|rigid:13anCpPEJYiB0tB5LzQ9S5O5LCI false firefly luciferase protein tag:n-n("MI:1208")|sufficient binding region:64-257("MI:0442") tandem tag:n-n("MI:0677") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q9NWB7 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-725672|intact:EBI-1581177|uniprotkb:Q96DA9|ensembl:ENSP00000264538 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:ift57_human(display_long)|uniprotkb:IFT57(gene name)|psi-mi:IFT57(display_short)|uniprotkb:DERP8(gene name synonym)|uniprotkb:ESRRBL1(gene name synonym)|uniprotkb:HIPPI(gene name synonym)|uniprotkb:HIP1-interacting protein(gene name synonym)|uniprotkb:Estrogen-related receptor beta-like protein 1(gene name synonym)|uniprotkb:Dermal papilla-derived protein 8(gene name synonym)|uniprotkb:MHS4R2(gene name synonym) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9101036|imex:IM-21827-408 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_060480.1|ensembl:ENSG00000114446(gene)|ensembl:ENST00000264538(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003677"(DNA binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0030992"(intraciliary transport particle B)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044292"(dendrite terminus)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0060972"(left/right pattern formation)|go:"GO:0097542"(ciliary tip)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR019530|reactome:R-HSA-5610787|reactome:R-HSA-5620924|uniprotkb:Q9NWB7(identity)|entrezgene/locuslink:55081(identity) psi-mi:"MI:0469"(intact) - - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:dwediEVcY3c1oEqj6xTpaae4aTk9606 intact-crc:AD96634BFC53269C|rigid:JAgXWozzF4FmAyXVvNNV+/c8I5E false firefly luciferase protein tag:n-n("MI:1208")|sufficient binding region:1-257("MI:0442") tandem tag:n-n("MI:0677") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q9H4A5 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-4403434|uniprotkb:B7Z6N3|uniprotkb:B1AN09|uniprotkb:Q9NVK0|ensembl:ENSP00000271732 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:glp3l_human(display_long)|uniprotkb:GOLPH3L(gene name)|psi-mi:GOLPH3L(display_short)|uniprotkb:GPP34R(gene name synonym)|uniprotkb:GPP34-related protein(gene name synonym) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9101015|imex:IM-21827-407 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) refseq:NP_060648.2|ensembl:ENSG00000143457(gene)|ensembl:ENST00000271732(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007030"(Golgi organization)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|interpro:IPR008628(Golgi phosphoprotein 3)|interpro:IPR038261|mint:Q9H4A5|uniprotkb:Q9H4A5(identity)|entrezgene/locuslink:55204(identity) psi-mi:"MI:0469"(intact) - - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:E+0Ru85nv0KoO/LW0kZLN1vpbFc9606 intact-crc:35027AA097BA76AE|rigid:Lx0FrpCKgYYOgguNZ5BPrhF0esM false firefly luciferase protein tag:n-n("MI:1208")|sufficient binding region:64-257("MI:0442") tandem tag:n-n("MI:0677") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UHY8 uniprotkb:Q8IUH5 intact:EBI-396453|uniprotkb:Q76LN0|uniprotkb:Q99690|uniprotkb:Q5EBN3|intact:EBI-28984869|ensembl:ENSP00000385112 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:fez2_human(display_long)|uniprotkb:FEZ2(gene name)|psi-mi:FEZ2(display_short)|uniprotkb:Zygin-2(gene name synonym)|uniprotkb:Zygin II(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9101078|imex:IM-21827-410 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036013.1|refseq:NP_005093.2|ensembl:ENST00000379245|ensembl:ENSP00000368547|ensembl:ENSP00000385112|ensembl:ENSG00000171055(gene)|ensembl:ENST00000405912(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0030424"(axon)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR011680(FEZ-like)|interpro:IPR015641(Fasciculation and elongation protein zeta 2)|mint:Q9UHY8|uniprotkb:Q9UHY8(identity)|entrezgene/locuslink:9637(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:n5uH+vdgrrvmI+PYkcMUEnAzxwE9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:8AA8F0223FE2743F|rigid:GO+MMpsXWNWtmeuSVCaqXwlLXpU false tandem tag:n-n("MI:0677") sufficient binding region:1-257("MI:0442")|firefly luciferase protein tag:n-n("MI:1208") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UI08-2 uniprotkb:Q8IUH5 intact:EBI-6448852|ensembl:ENSP00000376652 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:q9ui08-2(display_long)|uniprotkb:EVL(gene name)|psi-mi:EVL(display_short)|uniprotkb:Ena/vasodilator-stimulated phosphoprotein-like(gene name synonym)|uniprotkb:RNB6(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9101099|imex:IM-21827-411 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-346653(isoform-parent)|uniprotkb:Q9UI08-2(isoform-parent)|ensembl:ENSG00000196405(gene)|ensembl:ENST00000392920(transcript)|uniprotkb:Q9UI08-2(identity)|entrezgene/locuslink:51466(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:vlsreFW75TROSmoknoqbohf76HY9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:F60EE1D136FE3C1F|rigid:y3jD+lQ8lS1wU42U31Xt2VQeHfI false tandem tag:n-n("MI:0677") firefly luciferase protein tag:n-n("MI:1208")|sufficient binding region:1-257("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q9UJD0 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-3909436|ensembl:ENSP00000361768|ensembl:ENSP00000361769|uniprotkb:D3DPV8|uniprotkb:Q92511|uniprotkb:X5D7U7 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:rims3_human(display_long)|uniprotkb:RIMS3(gene name)|psi-mi:RIMS3(display_short)|uniprotkb:KIAA0237(gene name synonym)|uniprotkb:RIM3 gamma(gene name synonym)|uniprotkb:Rab-3-interacting molecule 3(gene name synonym) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9101120|imex:IM-21827-412 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) ensembl:ENSG00000117016(gene)|ensembl:ENST00000372683(transcript)|ensembl:ENST00000372684(transcript)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0048791"(calcium ion-regulated exocytosis of neurotransmitter)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR035892|interpro:IPR039032|refseq:NP_055562.2|uniprotkb:Q9UJD0(identity)|entrezgene/locuslink:9783(identity) psi-mi:"MI:0469"(intact) - - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:NblGKOuN12f+mXOrdc//beoOPQ09606 intact-crc:A4EE003B1D12C818|rigid:vXExPow2ySg++jy8y5uOCOfQ6s8 false firefly luciferase protein tag:n-n("MI:1208")|sufficient binding region:64-257("MI:0442") tandem tag:n-n("MI:0677") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27986-2 uniprotkb:Q8IUH5 intact:EBI-9090282|ensembl:ENSP00000338554 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:p27986-2(display_long)|uniprotkb:PIK3R1(gene name)|psi-mi:PIK3R1(display_short)|uniprotkb:GRB1(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha(gene name synonym)|uniprotkb:AS53(isoform synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9101183|imex:IM-21827-415 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145675(gene)|ensembl:ENST00000336483(transcript)|intact:EBI-79464(isoform-parent)|uniprotkb:P27986-2(isoform-parent)|uniprotkb:P27986-2(identity)|entrezgene/locuslink:5295(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:QtFCNbZABbNcR8Cd7rk+QMroFYM9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:0056CD2FCDD4C890|rigid:QgMDMGlVHDtrblv9qUN+FPUO5AI false tandem tag:n-n("MI:0677") firefly luciferase protein tag:n-n("MI:1208")|sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17655 uniprotkb:Q8IUH5 intact:EBI-1028956|uniprotkb:Q16738|uniprotkb:Q6PJT3|uniprotkb:Q8WU26|uniprotkb:Q9HBB1|uniprotkb:A6NDG7|ensembl:ENSP00000295006|uniprotkb:B7ZA96|uniprotkb:E7ES58 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:can2_human(display_long)|uniprotkb:CAPN2(gene name)|psi-mi:CAPN2(display_short)|uniprotkb:CANPL2(gene name synonym)|uniprotkb:Calpain-2 large subunit(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase 2(gene name synonym)|uniprotkb:Calpain M-type(gene name synonym)|uniprotkb:Millimolar-calpain(gene name synonym)|uniprotkb:Calpain large polypeptide L2(gene name synonym) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9101162|imex:IM-21827-414 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001139540.1|refseq:NP_001739.2|ensembl:ENSG00000162909(gene)|ensembl:ENST00000295006(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001824"(blastocyst development)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006508"(proteolysis)|go:"GO:0007520"(myoblast fusion)|go:"GO:0007565"(female pregnancy)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031143"(pseudopodium)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0005634"(nucleus)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048266"(behavioral response to pain)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901741"(positive regulation of myoblast fusion)|go:"GO:2001247"(positive regulation of phosphatidylcholine biosynthetic process)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR001300(Peptidase C2, calpain)|go:"GO:0005737"(cytoplasm)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022682|interpro:IPR022683|interpro:IPR022684|interpro:IPR029539|interpro:IPR033883|interpro:IPR036213|interpro:IPR038765|interpro:IPR042736|mint:P17655|rcsb pdb:1KFU|rcsb pdb:1KFX|rcsb pdb:2NQA|reactome:R-HSA-1474228|reactome:R-HSA-8862803|interpro:IPR002048(Calcium-binding EF-hand)|uniprotkb:P17655(identity)|entrezgene/locuslink:824(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) - - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:r60XX66kihGVLaa9888soeXjc0M9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:87070979CB2B6D79|rigid:T7f5rF5S5BsYb730MlW+3KGKdEY false tandem tag:n-n("MI:0677") firefly luciferase protein tag:n-n("MI:1208")|sufficient binding region:64-487("MI:0442") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:O14662-3 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-9093227|ensembl:ENSP00000434369 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:o14662-3(display_long)|uniprotkb:STX16(gene name)|psi-mi:STX16(display_short) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9101141|imex:IM-21827-413 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) intact:EBI-2853548(isoform-parent)|ensembl:ENSG00000124222(gene)|ensembl:ENST00000467096(transcript)|uniprotkb:O14662-3(identity)|entrezgene/locuslink:8675(identity) psi-mi:"MI:0469"(intact) - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:Trp+MFhsxgIRGsz6vX14Qpl+nWM9606 intact-crc:CD86FE81DF3D7033|rigid:ewOcopC+cKQ/gW3gXWKpNPVQAEI false firefly luciferase protein tag:n-n("MI:1208")|sufficient binding region:64-487("MI:0442") tandem tag:n-n("MI:0677") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q16537 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-968374|uniprotkb:B7ZAW5|uniprotkb:J3KQN6|ensembl:ENSP00000337641|uniprotkb:Q52LW4|uniprotkb:A4FU37|uniprotkb:B7ZKK8|intact:EBI-10962508|uniprotkb:B7ZKK9 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:2a5e_human(display_long)|uniprotkb:PPP2R5E(gene name)|psi-mi:PPP2R5E(display_short)|uniprotkb:PP2A B subunit isoform B'-epsilon(gene name synonym)|uniprotkb:PP2A B subunit isoform B56-epsilon(gene name synonym)|uniprotkb:PP2A B subunit isoform PR61-epsilon(gene name synonym)|uniprotkb:PP2A B subunit isoform R5-epsilon(gene name synonym) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9101228|imex:IM-21827-417 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) ensembl:ENSG00000154001(gene)|ensembl:ENST00000337537(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0072542"(protein phosphatase activator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR016024(Armadillo-type fold)|mint:Q16537|reactome:R-HSA-141444|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-9648025|interpro:IPR011989(Armadillo-like helical)|refseq:NP_006237.1|refseq:NP_001269108.1|refseq:NP_001269109.1|refseq:NP_001269110.1|refseq:NP_001269111.1|uniprotkb:Q16537(identity)|entrezgene/locuslink:5529(identity) psi-mi:"MI:0469"(intact) - - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:m6vjnzx9eg+HpXrI2KKBLPbObzA9606 intact-crc:B1E68E7CDDAC8542|rigid:sYX2FZFmJX+/8NpuJ8ILxsDz1q8 false sufficient binding region:64-487("MI:0442")|firefly luciferase protein tag:n-n("MI:1208") tandem tag:n-n("MI:0677") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUH5 uniprotkb:Q08379 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202 psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9101204|imex:IM-21827-416 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|uniprotkb:Q08379(identity)|entrezgene/locuslink:2801(identity) psi-mi:"MI:0469"(intact) - - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606 intact-crc:97595BE0AE2D3BA4|rigid:jUrGhSZ1tfwLFKP5a6r9EIHD9PM false firefly luciferase protein tag:n-n("MI:1208")|sufficient binding region:64-487("MI:0442") sufficient binding region:13-1002("MI:0442")|tandem tag:n-n("MI:0677") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7Z698 uniprotkb:Q8IUH5 intact:EBI-7082156|ensembl:ENSP00000348753|uniprotkb:A1L3V4|uniprotkb:B7Z5K7|intact:MINT-8020116|uniprotkb:Q2NKX6|uniprotkb:E9PEP0|uniprotkb:D6W5F7 intact:EBI-524753|uniprotkb:O75407|uniprotkb:Q7Z2I0|uniprotkb:Q86W89|uniprotkb:Q86YK0|uniprotkb:Q9P088|uniprotkb:Q9UPZ8|uniprotkb:B4DR39|ensembl:ENSP00000403397 psi-mi:spre2_human(display_long)|uniprotkb:SPRED2(gene name)|psi-mi:SPRED2(display_short) psi-mi:zdh17_human(display_long)|uniprotkb:HYPH(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 17(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14(gene name synonym)|uniprotkb:Huntingtin-interacting protein 3(gene name synonym)|uniprotkb:Huntingtin-interacting protein H(gene name synonym)|uniprotkb:Huntingtin yeast partner H(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 205(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM11(gene name synonym)|uniprotkb:HIP14(gene name synonym)|uniprotkb:HSPC294(orf name)|uniprotkb:KIAA0946(gene name synonym)|uniprotkb:ZDHHC17(gene name)|psi-mi:ZDHHC17(display_short)|uniprotkb:HIP3(gene name synonym)|uniprotkb:Acyltransferase ZDHHC17(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 17(gene name synonym) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Butland et al. (2014) imex:IM-21827|pubmed:24705354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9101249|imex:IM-21827-418 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000198369(gene)|ensembl:ENST00000356388(transcript)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0005173"(stem cell factor receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:1902747"(negative regulation of lens fiber cell differentiation)|interpro:IPR000697(EVH1)|interpro:IPR007875(Sprouty)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023337|interpro:IPR041937|rcsb pdb:2JP2|reactome:R-HSA-5658442|reactome:R-HSA-5658623|reactome:R-HSA-6802953|refseq:NP_861449.2|refseq:NP_001121682.1|uniprotkb:Q7Z698(identity)|entrezgene/locuslink:200734(identity) refseq:NP_056151.2|ensembl:ENST00000426126(transcript)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000186908(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016235"(aggresome)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0007409"(axonogenesis)|interpro:IPR030289|interpro:IPR036770|rcsb pdb:3EU9|rcsb pdb:5W7I|rcsb pdb:5W7J|uniprotkb:Q8IUH5(identity)|refseq:NP_056151(identity) psi-mi:"MI:0469"(intact) comment:mint - figure legend:Table 2 and supplementary table S3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/12/19 2014/10/16 rogid:Ao93NebBS40A8fFJk5b2ttbat0I9606 rogid:BmHSx6xanF0tt7bho0j+H06BF689606 intact-crc:3D27AA4F80B9E889|rigid:40vtx39wrol3pP7yYIACxFQTNM4 false tandem tag:n-n("MI:0677") sufficient binding region:64-487("MI:0442")|firefly luciferase protein tag:n-n("MI:1208") - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)