#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q53GS7	uniprotkb:Q53GS7	intact:EBI-1955541|uniprotkb:O75458|uniprotkb:Q53GT9|uniprotkb:Q5VVU1|uniprotkb:Q8NCP6|uniprotkb:Q9UFL6|ensembl:ENSP00000308622	intact:EBI-1955541|uniprotkb:O75458|uniprotkb:Q53GT9|uniprotkb:Q5VVU1|uniprotkb:Q8NCP6|uniprotkb:Q9UFL6|ensembl:ENSP00000308622	psi-mi:gle1_human(display_long)|uniprotkb:GLE1(gene name)|psi-mi:GLE1(display_short)|uniprotkb:GLE1L(gene name synonym)|uniprotkb:GLE1-like protein(gene name synonym)|uniprotkb:GLE1 RNA export mediator(gene name synonym)|uniprotkb:Nucleoporin GLE1(gene name synonym)	psi-mi:gle1_human(display_long)|uniprotkb:GLE1(gene name)|psi-mi:GLE1(display_short)|uniprotkb:GLE1L(gene name synonym)|uniprotkb:GLE1-like protein(gene name synonym)|uniprotkb:GLE1 RNA export mediator(gene name synonym)|uniprotkb:Nucleoporin GLE1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Folkmann et al. (2013)	imex:IM-21748|pubmed:24243016	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8873329|imex:IM-21748-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001003722.1|refseq:NP_001490.1|ensembl:ENSG00000119392(gene)|ensembl:ENST00000309971(transcript)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|interpro:IPR012476(GLE1-like)|interpro:IPR038506|rcsb pdb:6B4F|rcsb pdb:6B4I|rcsb pdb:6B4J|reactome:R-HSA-159236	refseq:NP_001003722.1|refseq:NP_001490.1|ensembl:ENSG00000119392(gene)|ensembl:ENST00000309971(transcript)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|interpro:IPR012476(GLE1-like)|interpro:IPR038506|rcsb pdb:6B4F|rcsb pdb:6B4I|rcsb pdb:6B4J|reactome:R-HSA-159236	-	-	-	figure legend:Supp Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/11/25	2014/10/16	rogid:wdG5CPG2bIFZun0cyQ9jyPK7e9s9606	rogid:wdG5CPG2bIFZun0cyQ9jyPK7e9s9606	intact-crc:59FEF4EF57B256C6|rigid:96y/bRyae/5/Cs6RIWxGFfD0C+A	false	glutathione s tranferase tag:?-?|sufficient binding region:1-362	35s radiolabel:?-?|sufficient binding region:1-362	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q53GS7	uniprotkb:Q53GS7	intact:EBI-1955541|uniprotkb:O75458|uniprotkb:Q53GT9|uniprotkb:Q5VVU1|uniprotkb:Q8NCP6|uniprotkb:Q9UFL6|ensembl:ENSP00000308622	intact:EBI-1955541|uniprotkb:O75458|uniprotkb:Q53GT9|uniprotkb:Q5VVU1|uniprotkb:Q8NCP6|uniprotkb:Q9UFL6|ensembl:ENSP00000308622	psi-mi:gle1_human(display_long)|uniprotkb:GLE1(gene name)|psi-mi:GLE1(display_short)|uniprotkb:GLE1L(gene name synonym)|uniprotkb:GLE1-like protein(gene name synonym)|uniprotkb:GLE1 RNA export mediator(gene name synonym)|uniprotkb:Nucleoporin GLE1(gene name synonym)	psi-mi:gle1_human(display_long)|uniprotkb:GLE1(gene name)|psi-mi:GLE1(display_short)|uniprotkb:GLE1L(gene name synonym)|uniprotkb:GLE1-like protein(gene name synonym)|uniprotkb:GLE1 RNA export mediator(gene name synonym)|uniprotkb:Nucleoporin GLE1(gene name synonym)	psi-mi:"MI:0040"(electron microscopy)	Folkmann et al. (2013)	imex:IM-21748|pubmed:24243016	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8873433|imex:IM-21748-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001003722.1|refseq:NP_001490.1|ensembl:ENSG00000119392(gene)|ensembl:ENST00000309971(transcript)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|interpro:IPR012476(GLE1-like)|interpro:IPR038506|rcsb pdb:6B4F|rcsb pdb:6B4I|rcsb pdb:6B4J|reactome:R-HSA-159236	refseq:NP_001003722.1|refseq:NP_001490.1|ensembl:ENSG00000119392(gene)|ensembl:ENST00000309971(transcript)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|interpro:IPR012476(GLE1-like)|interpro:IPR038506|rcsb pdb:6B4F|rcsb pdb:6B4I|rcsb pdb:6B4J|reactome:R-HSA-159236	-	-	-	comment:"The major lethal congenital contracture syndrome-1 causative mutation in hGLE1 is designated Fin(Major). FinMajor  (1–362) formed structurally disorganised disc-shaped particles."|figure legend:Fig. 2C, 2D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2013/11/25	2014/10/16	rogid:wdG5CPG2bIFZun0cyQ9jyPK7e9s9606	rogid:wdG5CPG2bIFZun0cyQ9jyPK7e9s9606	intact-crc:0033E44D07F9DCBF|rigid:96y/bRyae/5/Cs6RIWxGFfD0C+A	false	maltose binding protein tag:?-?|sufficient binding region:1-362|disease causing amino-acid variant:144-144	maltose binding protein tag:?-?|disease causing amino-acid variant:144-144|sufficient binding region:1-362	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q53GS7	uniprotkb:Q53GS7	intact:EBI-1955541|uniprotkb:O75458|uniprotkb:Q53GT9|uniprotkb:Q5VVU1|uniprotkb:Q8NCP6|uniprotkb:Q9UFL6|ensembl:ENSP00000308622	intact:EBI-1955541|uniprotkb:O75458|uniprotkb:Q53GT9|uniprotkb:Q5VVU1|uniprotkb:Q8NCP6|uniprotkb:Q9UFL6|ensembl:ENSP00000308622	psi-mi:gle1_human(display_long)|uniprotkb:GLE1(gene name)|psi-mi:GLE1(display_short)|uniprotkb:GLE1L(gene name synonym)|uniprotkb:GLE1-like protein(gene name synonym)|uniprotkb:GLE1 RNA export mediator(gene name synonym)|uniprotkb:Nucleoporin GLE1(gene name synonym)	psi-mi:gle1_human(display_long)|uniprotkb:GLE1(gene name)|psi-mi:GLE1(display_short)|uniprotkb:GLE1L(gene name synonym)|uniprotkb:GLE1-like protein(gene name synonym)|uniprotkb:GLE1 RNA export mediator(gene name synonym)|uniprotkb:Nucleoporin GLE1(gene name synonym)	psi-mi:"MI:0040"(electron microscopy)	Folkmann et al. (2013)	imex:IM-21748|pubmed:24243016	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8873430|imex:IM-21748-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001003722.1|refseq:NP_001490.1|ensembl:ENSG00000119392(gene)|ensembl:ENST00000309971(transcript)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|interpro:IPR012476(GLE1-like)|interpro:IPR038506|rcsb pdb:6B4F|rcsb pdb:6B4I|rcsb pdb:6B4J|reactome:R-HSA-159236	refseq:NP_001003722.1|refseq:NP_001490.1|ensembl:ENSG00000119392(gene)|ensembl:ENST00000309971(transcript)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|interpro:IPR012476(GLE1-like)|interpro:IPR038506|rcsb pdb:6B4F|rcsb pdb:6B4I|rcsb pdb:6B4J|reactome:R-HSA-159236	-	-	-	figure legend:Fig. 2A, 2B|comment:"MBP-hGle1(1–362) formed ring/disk structures."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2013/11/25	2014/10/16	rogid:wdG5CPG2bIFZun0cyQ9jyPK7e9s9606	rogid:wdG5CPG2bIFZun0cyQ9jyPK7e9s9606	intact-crc:A65BE6098D5D3E92|rigid:96y/bRyae/5/Cs6RIWxGFfD0C+A	false	maltose binding protein tag:?-?|sufficient binding region:1-362	maltose binding protein tag:?-?|sufficient binding region:1-362	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q53GS7-1	uniprotkb:Q53GS7-1	intact:EBI-8873506|ensembl:ENSP00000308622	intact:EBI-8873506|ensembl:ENSP00000308622	psi-mi:q53gs7-1(display_long)|uniprotkb:GLE1(gene name)|psi-mi:GLE1(display_short)|uniprotkb:GLE1L(gene name synonym)|uniprotkb:GLE1-like protein(gene name synonym)|uniprotkb:GLE1 RNA export mediator(gene name synonym)|uniprotkb:Nucleoporin GLE1(gene name synonym)|uniprotkb:hGle1B(isoform synonym)	psi-mi:q53gs7-1(display_long)|uniprotkb:GLE1(gene name)|psi-mi:GLE1(display_short)|uniprotkb:GLE1L(gene name synonym)|uniprotkb:GLE1-like protein(gene name synonym)|uniprotkb:GLE1 RNA export mediator(gene name synonym)|uniprotkb:Nucleoporin GLE1(gene name synonym)|uniprotkb:hGle1B(isoform synonym)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Folkmann et al. (2013)	imex:IM-21748|pubmed:24243016	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8873491|imex:IM-21748-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1955541(isoform-parent)|ensembl:ENSG00000119392(gene)|ensembl:ENST00000309971(transcript)	intact:EBI-1955541(isoform-parent)|ensembl:ENSG00000119392(gene)|ensembl:ENST00000309971(transcript)	go:"GO:0031965"(nuclear membrane)	isoform-comment:Major isoform.	isoform-comment:Major isoform.	figure legend:Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2013/11/25	2014/10/16	rogid:wdG5CPG2bIFZun0cyQ9jyPK7e9s9606	rogid:wdG5CPG2bIFZun0cyQ9jyPK7e9s9606	intact-crc:6BF22CEC0ACF9D0A|rigid:96y/bRyae/5/Cs6RIWxGFfD0C+A	false	fluorescent protein tag:?-?	venus fluorescent protein tag:?-?|necessary binding region:1-361	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q53GS7	uniprotkb:Q53GS7	intact:EBI-1955541|uniprotkb:O75458|uniprotkb:Q53GT9|uniprotkb:Q5VVU1|uniprotkb:Q8NCP6|uniprotkb:Q9UFL6|ensembl:ENSP00000308622	intact:EBI-1955541|uniprotkb:O75458|uniprotkb:Q53GT9|uniprotkb:Q5VVU1|uniprotkb:Q8NCP6|uniprotkb:Q9UFL6|ensembl:ENSP00000308622	psi-mi:gle1_human(display_long)|uniprotkb:GLE1(gene name)|psi-mi:GLE1(display_short)|uniprotkb:GLE1L(gene name synonym)|uniprotkb:GLE1-like protein(gene name synonym)|uniprotkb:GLE1 RNA export mediator(gene name synonym)|uniprotkb:Nucleoporin GLE1(gene name synonym)	psi-mi:gle1_human(display_long)|uniprotkb:GLE1(gene name)|psi-mi:GLE1(display_short)|uniprotkb:GLE1L(gene name synonym)|uniprotkb:GLE1-like protein(gene name synonym)|uniprotkb:GLE1 RNA export mediator(gene name synonym)|uniprotkb:Nucleoporin GLE1(gene name synonym)	psi-mi:"MI:0028"(cosedimentation in solution)	Folkmann et al. (2013)	imex:IM-21748|pubmed:24243016	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8873372|imex:IM-21748-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001003722.1|refseq:NP_001490.1|ensembl:ENSG00000119392(gene)|ensembl:ENST00000309971(transcript)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|interpro:IPR012476(GLE1-like)|interpro:IPR038506|rcsb pdb:6B4F|rcsb pdb:6B4I|rcsb pdb:6B4J|reactome:R-HSA-159236	refseq:NP_001003722.1|refseq:NP_001490.1|ensembl:ENSG00000119392(gene)|ensembl:ENST00000309971(transcript)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|interpro:IPR012476(GLE1-like)|interpro:IPR038506|rcsb pdb:6B4F|rcsb pdb:6B4I|rcsb pdb:6B4J|reactome:R-HSA-159236	-	-	-	comment:"The major lethal congenital contracture syndrome-1 causative mutation in hGLE1 is designated Fin(Major). FinMajor  (1–362) sedimented in a series of distinct peaks ranging from 0.097 MDa to 1.9 MDa"|figure legend:Supp. Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2013/11/25	2014/10/16	rogid:wdG5CPG2bIFZun0cyQ9jyPK7e9s9606	rogid:wdG5CPG2bIFZun0cyQ9jyPK7e9s9606	intact-crc:5F5D5CE40366249B|rigid:96y/bRyae/5/Cs6RIWxGFfD0C+A	false	maltose binding protein tag:?-?|sufficient binding region:1-362|disease causing amino-acid variant:144-144	maltose binding protein tag:?-?|sufficient binding region:1-362|disease causing amino-acid variant:144-144	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q53GS7	uniprotkb:Q53GS7	intact:EBI-1955541|uniprotkb:O75458|uniprotkb:Q53GT9|uniprotkb:Q5VVU1|uniprotkb:Q8NCP6|uniprotkb:Q9UFL6|ensembl:ENSP00000308622	intact:EBI-1955541|uniprotkb:O75458|uniprotkb:Q53GT9|uniprotkb:Q5VVU1|uniprotkb:Q8NCP6|uniprotkb:Q9UFL6|ensembl:ENSP00000308622	psi-mi:gle1_human(display_long)|uniprotkb:GLE1(gene name)|psi-mi:GLE1(display_short)|uniprotkb:GLE1L(gene name synonym)|uniprotkb:GLE1-like protein(gene name synonym)|uniprotkb:GLE1 RNA export mediator(gene name synonym)|uniprotkb:Nucleoporin GLE1(gene name synonym)	psi-mi:gle1_human(display_long)|uniprotkb:GLE1(gene name)|psi-mi:GLE1(display_short)|uniprotkb:GLE1L(gene name synonym)|uniprotkb:GLE1-like protein(gene name synonym)|uniprotkb:GLE1 RNA export mediator(gene name synonym)|uniprotkb:Nucleoporin GLE1(gene name synonym)	psi-mi:"MI:0028"(cosedimentation in solution)	Folkmann et al. (2013)	imex:IM-21748|pubmed:24243016	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8873347|imex:IM-21748-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001003722.1|refseq:NP_001490.1|ensembl:ENSG00000119392(gene)|ensembl:ENST00000309971(transcript)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|interpro:IPR012476(GLE1-like)|interpro:IPR038506|rcsb pdb:6B4F|rcsb pdb:6B4I|rcsb pdb:6B4J|reactome:R-HSA-159236	refseq:NP_001003722.1|refseq:NP_001490.1|ensembl:ENSG00000119392(gene)|ensembl:ENST00000309971(transcript)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|interpro:IPR012476(GLE1-like)|interpro:IPR038506|rcsb pdb:6B4F|rcsb pdb:6B4I|rcsb pdb:6B4J|reactome:R-HSA-159236	-	-	-	comment:"MBP-hGle1(1–362) protomer itself has a predicted molecular mass of 0.084 MDa.  MBP-hGle1(1–362) sedimented in a series of distinct peaks corresponding to at least eight species with high relative molecular masses ranging from 0.096 MDa to 2.0 MDa"|figure legend:Supp. Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2013/11/25	2014/10/16	rogid:wdG5CPG2bIFZun0cyQ9jyPK7e9s9606	rogid:wdG5CPG2bIFZun0cyQ9jyPK7e9s9606	intact-crc:6DB22D6E90A06AFE|rigid:96y/bRyae/5/Cs6RIWxGFfD0C+A	false	maltose binding protein tag:?-?|sufficient binding region:1-362	sufficient binding region:1-362|maltose binding protein tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12315	uniprotkb:Q12315	intact:EBI-7635|uniprotkb:D6VRE7|ensemblfungi:YDL207W	intact:EBI-7635|uniprotkb:D6VRE7|ensemblfungi:YDL207W	psi-mi:gle1_yeast(display_long)|uniprotkb:BRR3(gene name synonym)|uniprotkb:RSS1(gene name synonym)|uniprotkb:YDL207W(locus name)|uniprotkb:D1049(orf name)|uniprotkb:GLE1(gene name)|psi-mi:GLE1(display_short)|uniprotkb:Nuclear pore protein GLE1(gene name synonym)|uniprotkb:RNA export factor GLE1(gene name synonym)|uniprotkb:Nucleoporin GLE1(gene name synonym)	psi-mi:gle1_yeast(display_long)|uniprotkb:BRR3(gene name synonym)|uniprotkb:RSS1(gene name synonym)|uniprotkb:YDL207W(locus name)|uniprotkb:D1049(orf name)|uniprotkb:GLE1(gene name)|psi-mi:GLE1(display_short)|uniprotkb:Nuclear pore protein GLE1(gene name synonym)|uniprotkb:RNA export factor GLE1(gene name synonym)|uniprotkb:Nucleoporin GLE1(gene name synonym)	psi-mi:"MI:0040"(electron microscopy)	Folkmann et al. (2013)	imex:IM-21748|pubmed:24243016	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8873470|imex:IM-21748-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002366|refseq:NP_010074.1|mint:Q12315|dip:DIP-2350N|ensemblfungi:YDL207W(gene)|ensemblfungi:YDL207W_mRNA(transcript)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0015031"(protein transport)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|interpro:IPR012476(GLE1-like)|interpro:IPR038506|rcsb pdb:3PEU|rcsb pdb:3PEV|rcsb pdb:3RRM|rcsb pdb:3RRN|rcsb pdb:6B4E	sgd:S000002366|refseq:NP_010074.1|mint:Q12315|dip:DIP-2350N|ensemblfungi:YDL207W(gene)|ensemblfungi:YDL207W_mRNA(transcript)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0015031"(protein transport)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|interpro:IPR012476(GLE1-like)|interpro:IPR038506|rcsb pdb:3PEU|rcsb pdb:3PEV|rcsb pdb:3RRM|rcsb pdb:3RRN|rcsb pdb:6B4E	-	crc64:C9C6B1513AF95711	crc64:C9C6B1513AF95711	figure legend:Fig. 2H/I|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2013/11/25	2014/10/16	rogid:1RI51/DOenI6DQvh2tErmJnDffI559292	rogid:1RI51/DOenI6DQvh2tErmJnDffI559292	intact-crc:5775566BC4F22999|rigid:FNe/AU8eMFTvoCR8s5lyFAgvgU4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q53GS7	uniprotkb:O75694	intact:EBI-1955541|uniprotkb:O75458|uniprotkb:Q53GT9|uniprotkb:Q5VVU1|uniprotkb:Q8NCP6|uniprotkb:Q9UFL6|ensembl:ENSP00000308622	intact:EBI-1050769|uniprotkb:Q9UBE9|uniprotkb:Q9UFL5|intact:EBI-28983292|ensembl:ENSP00000231498	psi-mi:gle1_human(display_long)|uniprotkb:GLE1(gene name)|psi-mi:GLE1(display_short)|uniprotkb:GLE1L(gene name synonym)|uniprotkb:GLE1-like protein(gene name synonym)|uniprotkb:GLE1 RNA export mediator(gene name synonym)|uniprotkb:Nucleoporin GLE1(gene name synonym)	psi-mi:nu155_human(display_long)|uniprotkb:Nucleoporin Nup155(gene name synonym)|uniprotkb:155 kDa nucleoporin(gene name synonym)|uniprotkb:KIAA0791(gene name synonym)|uniprotkb:NUP155(gene name)|psi-mi:NUP155(display_short)	psi-mi:"MI:0018"(two hybrid)	Folkmann et al. (2013)	imex:IM-21748|pubmed:24243016	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8873568|imex:IM-21748-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001003722.1|refseq:NP_001490.1|ensembl:ENSG00000119392(gene)|ensembl:ENST00000309971(transcript)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|interpro:IPR012476(GLE1-like)|interpro:IPR038506|rcsb pdb:6B4F|rcsb pdb:6B4I|rcsb pdb:6B4J|reactome:R-HSA-159236	refseq:NP_004289.1|refseq:NP_705618.1|ensembl:ENSP00000231498|ensembl:ENST00000381843|ensembl:ENSP00000371265|ensembl:ENSG00000113569(gene)|ensembl:ENST00000231498(transcript)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0016020"(membrane)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044611"(nuclear pore inner ring)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|interpro:IPR004870(Nucleoporin, non-repetitive/WGA-negative)|interpro:IPR007187(Nucleoporin, Nup133-like, C-terminal)|interpro:IPR014908(Nup133, N-terminal)|interpro:IPR042533|interpro:IPR042537|interpro:IPR042538|rcsb pdb:5A9Q|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933	-	-	-	figure legend:Supp. Fig. 3A|comment:"Results using the GBD-FinMajor Bait (with PFQ insertion) were similar to those obtained using wild-type GBD-hGle1B."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/11/25	2014/10/16	rogid:wdG5CPG2bIFZun0cyQ9jyPK7e9s9606	rogid:k6LjWvJdqtT78G4Wu12rJX/2WHo9606	intact-crc:88133952E99F739A|rigid:HyJcd1SNGvXNfuo++F3SFIa6e1o	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O00303	uniprotkb:Q53GS7	intact:EBI-711990|ensembl:ENSP00000431800|ensembl:ENSP00000499218|uniprotkb:Q6IB45|uniprotkb:Q8N978|uniprotkb:A8K0S2	intact:EBI-1955541|uniprotkb:O75458|uniprotkb:Q53GT9|uniprotkb:Q5VVU1|uniprotkb:Q8NCP6|uniprotkb:Q9UFL6|ensembl:ENSP00000308622	psi-mi:eif3f_human(display_long)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 5(gene name synonym)|uniprotkb:eIF-3-epsilon(gene name synonym)|uniprotkb:eIF3 p47(gene name synonym)|uniprotkb:EIF3F(gene name)|psi-mi:EIF3F(display_short)|uniprotkb:EIF3S5(gene name synonym)|uniprotkb:Deubiquitinating enzyme eIF3f(gene name synonym)	psi-mi:gle1_human(display_long)|uniprotkb:GLE1(gene name)|psi-mi:GLE1(display_short)|uniprotkb:GLE1L(gene name synonym)|uniprotkb:GLE1-like protein(gene name synonym)|uniprotkb:GLE1 RNA export mediator(gene name synonym)|uniprotkb:Nucleoporin GLE1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Folkmann et al. (2013)	imex:IM-21748|pubmed:24243016	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8873550|imex:IM-21748-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000175390(gene)|ensembl:ENST00000533626(transcript)|ensembl:ENST00000651655(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0101005"(deubiquitinase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR027531|interpro:IPR037518|mint:O00303|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:NP_003745.1|dip:DIP-35580N	refseq:NP_001003722.1|refseq:NP_001490.1|ensembl:ENSG00000119392(gene)|ensembl:ENST00000309971(transcript)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|interpro:IPR012476(GLE1-like)|interpro:IPR038506|rcsb pdb:6B4F|rcsb pdb:6B4I|rcsb pdb:6B4J|reactome:R-HSA-159236	-	-	-	figure legend:Supp. Fig. 3A|comment:"Results using the GBD-FinMajor Bait (with PFQ insertion) were similar to those obtained using wild-type GBD-hGle1B."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/11/25	2014/10/16	rogid:dpH1pTcPshcrSjNCdPPnkYiW0YU9606	rogid:wdG5CPG2bIFZun0cyQ9jyPK7e9s9606	intact-crc:C734A7ACBFAE730D|rigid:RkGCNwGodtHsaDwXVYxgK52TI9Q	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q53GS7	uniprotkb:Q86UP2	intact:EBI-1955541|uniprotkb:O75458|uniprotkb:Q53GT9|uniprotkb:Q5VVU1|uniprotkb:Q8NCP6|uniprotkb:Q9UFL6|ensembl:ENSP00000308622	intact:EBI-359761|uniprotkb:Q13999|uniprotkb:Q14707|uniprotkb:Q15387|uniprotkb:Q86W57|ensembl:ENSP00000378725|ensembl:ENSP00000432149|uniprotkb:Q17RZ5|uniprotkb:B4DZ88|uniprotkb:Q5GGW3	psi-mi:gle1_human(display_long)|uniprotkb:GLE1(gene name)|psi-mi:GLE1(display_short)|uniprotkb:GLE1L(gene name synonym)|uniprotkb:GLE1-like protein(gene name synonym)|uniprotkb:GLE1 RNA export mediator(gene name synonym)|uniprotkb:Nucleoporin GLE1(gene name synonym)	psi-mi:ktn1_human(display_long)|uniprotkb:KTN1(gene name)|psi-mi:KTN1(display_short)|uniprotkb:CG1(gene name synonym)|uniprotkb:KIAA0004(gene name synonym)|uniprotkb:Kinesin receptor(gene name synonym)|uniprotkb:CG-1 antigen(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Folkmann et al. (2013)	imex:IM-21748|pubmed:24243016	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8873563|imex:IM-21748-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001003722.1|refseq:NP_001490.1|ensembl:ENSG00000119392(gene)|ensembl:ENST00000309971(transcript)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|interpro:IPR012476(GLE1-like)|interpro:IPR038506|rcsb pdb:6B4F|rcsb pdb:6B4I|rcsb pdb:6B4J|reactome:R-HSA-159236	refseq:NP_001072989.1|refseq:NP_004977.2|ensembl:ENSG00000126777(gene)|ensembl:ENST00000395314(transcript)|ensembl:ENST00000459737(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045296"(cadherin binding)|interpro:IPR007794(Ribosome receptor lysine or proline rich)|interpro:IPR024854|mint:Q86UP2|refseq:XP_011535053.1|refseq:XP_011535055.1|reactome:R-HSA-381426|reactome:R-HSA-5625970|reactome:R-HSA-8957275|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013408|reactome:R-HSA-9696264|reactome:R-HSA-9696270|refseq:NP_001072990.1|refseq:NP_001257943.1|refseq:XP_006720201.1|refseq:XP_006720202.1|refseq:XP_016876767.1|refseq:XP_016876771.1|refseq:XP_016876772.1|dip:DIP-27585N	-	-	-	figure legend:Supp. Fig. 3A|comment:"Results using the GBD-FinMajor Bait (with PFQ insertion) were similar to those obtained using wild-type GBD-hGle1B."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/11/25	2014/10/16	rogid:wdG5CPG2bIFZun0cyQ9jyPK7e9s9606	rogid:paZIiw7G2n1qUQ91xj5zi8x1Oxc9606	intact-crc:85AAFED5432381A7|rigid:6ZTf6qf3G8SNlo8eiWam6Zm8GoY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15422"	uniprotkb:P20449	intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249"	intact:EBI-5617|uniprotkb:D6W2B2|ensemblfungi:YOR046C	psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:dbp5_yeast(display_long)|uniprotkb:YOR046C(locus name)|uniprotkb:DBP5(gene name)|psi-mi:DBP5(display_short)|uniprotkb:RAT8(gene name synonym)|uniprotkb:DEAD box protein 5(gene name synonym)|uniprotkb:Helicase CA5/6(gene name synonym)|uniprotkb:Ribonucleic acid-trafficking protein 8(gene name synonym)	psi-mi:"MI:0880"(atpase assay)	Folkmann et al. (2013)	imex:IM-21748|pubmed:24243016	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0882"(atpase reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8873583|imex:IM-21748-12	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_014689.1|sgd:S000005572|dip:DIP-2352N|mint:P20449|ensemblfungi:YOR046C(gene)|ensemblfungi:YOR046C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0005934"(cellular bud tip)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006415"(translational termination)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0015031"(protein transport)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031965"(nuclear membrane)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:2KBE|rcsb pdb:2KBF|rcsb pdb:3GFP|rcsb pdb:3PEU|rcsb pdb:3PEV|rcsb pdb:3PEW|rcsb pdb:3PEY|rcsb pdb:3RRM|rcsb pdb:3RRN|rcsb pdb:5ELX	go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0006200"(obsolete ATP catabolic process)	-	crc64:C50CAFE8C060D46B	figure legend:Supp. Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/11/25	2014/10/16	-	rogid:54iW7iCC7GTFWfgoHUq0Qv5WVMI559292	intact-crc:F7489D5B2A92B220	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15422"	uniprotkb:P20449	intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249"	intact:EBI-5617|uniprotkb:D6W2B2|ensemblfungi:YOR046C	psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:dbp5_yeast(display_long)|uniprotkb:YOR046C(locus name)|uniprotkb:DBP5(gene name)|psi-mi:DBP5(display_short)|uniprotkb:RAT8(gene name synonym)|uniprotkb:DEAD box protein 5(gene name synonym)|uniprotkb:Helicase CA5/6(gene name synonym)|uniprotkb:Ribonucleic acid-trafficking protein 8(gene name synonym)	psi-mi:"MI:0880"(atpase assay)	Folkmann et al. (2013)	imex:IM-21748|pubmed:24243016	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0882"(atpase reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8873595|imex:IM-21748-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_014689.1|sgd:S000005572|dip:DIP-2352N|mint:P20449|ensemblfungi:YOR046C(gene)|ensemblfungi:YOR046C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0005934"(cellular bud tip)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006415"(translational termination)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0015031"(protein transport)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031965"(nuclear membrane)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:2KBE|rcsb pdb:2KBF|rcsb pdb:3GFP|rcsb pdb:3PEU|rcsb pdb:3PEV|rcsb pdb:3PEW|rcsb pdb:3PEY|rcsb pdb:3RRM|rcsb pdb:3RRN|rcsb pdb:5ELX	go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0006200"(obsolete ATP catabolic process)	-	crc64:C50CAFE8C060D46B	figure legend:Supp. Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/11/25	2014/10/16	-	rogid:54iW7iCC7GTFWfgoHUq0Qv5WVMI559292	intact-crc:18C2D277D0CBCE21	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15422"	uniprotkb:Q12315	intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249"	intact:EBI-7635|uniprotkb:D6VRE7|ensemblfungi:YDL207W	psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:gle1_yeast(display_long)|uniprotkb:BRR3(gene name synonym)|uniprotkb:RSS1(gene name synonym)|uniprotkb:YDL207W(locus name)|uniprotkb:D1049(orf name)|uniprotkb:GLE1(gene name)|psi-mi:GLE1(display_short)|uniprotkb:Nuclear pore protein GLE1(gene name synonym)|uniprotkb:RNA export factor GLE1(gene name synonym)|uniprotkb:Nucleoporin GLE1(gene name synonym)	psi-mi:"MI:0880"(atpase assay)	Folkmann et al. (2013)	imex:IM-21748|pubmed:24243016	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0882"(atpase reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8873595|imex:IM-21748-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	sgd:S000002366|refseq:NP_010074.1|mint:Q12315|dip:DIP-2350N|ensemblfungi:YDL207W(gene)|ensemblfungi:YDL207W_mRNA(transcript)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0015031"(protein transport)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|interpro:IPR012476(GLE1-like)|interpro:IPR038506|rcsb pdb:3PEU|rcsb pdb:3PEV|rcsb pdb:3RRM|rcsb pdb:3RRN|rcsb pdb:6B4E	go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0006200"(obsolete ATP catabolic process)	-	crc64:C9C6B1513AF95711	figure legend:Supp. Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/11/25	2014/10/16	-	rogid:1RI51/DOenI6DQvh2tErmJnDffI559292	intact-crc:18C2D277D0CBCE21	false	-	sufficient binding region:241-538	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15422"	chebi:"CHEBI:17401"	intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249"	intact:EBI-1251377	psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:myo-inositol hexakisphosphate(display_short)|psi-mi:"CHEBI:17401"(display_long)	psi-mi:"MI:0880"(atpase assay)	Folkmann et al. (2013)	imex:IM-21748|pubmed:24243016	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0882"(atpase reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8873595|imex:IM-21748-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0328"(small molecule)	-	-	go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0006200"(obsolete ATP catabolic process)	-	-	figure legend:Supp. Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/11/25	2014/10/16	-	-	intact-crc:18C2D277D0CBCE21	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)