#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q92560	uniprotkb:P51610	intact:EBI-1791447|uniprotkb:Q6LEM0|uniprotkb:Q7Z5E8|uniprotkb:A8K993|intact:EBI-2558090|ensembl:ENSP00000417132	intact:EBI-396176|intact:EBI-2832627|uniprotkb:Q6P4G5|intact:EBI-12037257|intact:EBI-14324845|ensembl:ENSP00000309555|intact:EBI-12980473	psi-mi:bap1_human(display_long)|uniprotkb:BAP1(gene name)|psi-mi:BAP1(display_short)|uniprotkb:KIAA0272(gene name synonym)|uniprotkb:hucep-6(orf name)|uniprotkb:BRCA1-associated protein 1(gene name synonym)|uniprotkb:Cerebral protein 6(gene name synonym)	psi-mi:hcfc1_human(display_long)|uniprotkb:HCFC1(gene name)|psi-mi:HCFC1(display_short)|uniprotkb:HCF1(gene name synonym)|uniprotkb:C1 factor(gene name synonym)|uniprotkb:VP16 accessory protein(gene name synonym)|uniprotkb:VCAF(gene name synonym)|uniprotkb:CFF(gene name synonym)|uniprotkb:HFC1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ziad et al. (2013)	pubmed:24211834|imex:IM-21711	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8829605|imex:IM-21711-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-47004N|refseq:NP_004647.1|ensembl:ENSG00000163930(gene)|ensembl:ENST00000460680(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003682"(chromatin binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008233"(peptidase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061519"(macrophage homeostasis)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:1900015"(regulation of cytokine production involved in inflammatory response)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q92560|reactome:R-HSA-5689603|reactome:R-HSA-5693565	refseq:NP_005325.2|refseq:XP_006724879.1|rcsb pdb:6MA1|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|reactome:R-HSA-2151201|reactome:R-HSA-3214847|reactome:R-HSA-5689603|ensembl:ENSG00000172534(gene)|ensembl:ENST00000310441(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0019046"(release from viral latency)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045296"(cadherin binding)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR036116|interpro:IPR037854|interpro:IPR043536|mint:P51610|rcsb pdb:4GO6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:5LWV|dip:DIP-32955N	-	-	-	figure legend:f1b|comment:"To further assess whether the pS592-BAP1 antibody recognizes phosphorylated BAP1, we  performed IPs of BAP1 and HCF-1 from endogenous HeLa SCEs (Fig 1B). Consistent with previous  reports [5, 8], BAP1 only brings down a small fraction of HCF-1, while HCF-1 brings down a  significant fraction of BAP1. In the absence of UV, there is no detectable pS592-signal in the IP inputs,  yet after UV-treatment the pS592-BAP1 signal is induced and both BAP1 and HCF-1 coimmunoprecipitate  pS592-BAP1."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2013/10/25	2014/10/16	rogid:GMWdT1u5HUl29N+YgC/bCKTbxm49606	rogid:RzsCRe9l6md3DI87H4ZgdR9oBMI9606	intact-crc:9F850C3E083BA221|rigid:KovQxPFbp2E/brl9/j0+7Ru7RB4	false	phosphorylated residue:592-592	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q92560	uniprotkb:P51610	intact:EBI-1791447|uniprotkb:Q6LEM0|uniprotkb:Q7Z5E8|uniprotkb:A8K993|intact:EBI-2558090|ensembl:ENSP00000417132	intact:EBI-396176|intact:EBI-2832627|uniprotkb:Q6P4G5|intact:EBI-12037257|intact:EBI-14324845|ensembl:ENSP00000309555|intact:EBI-12980473	psi-mi:bap1_human(display_long)|uniprotkb:BAP1(gene name)|psi-mi:BAP1(display_short)|uniprotkb:KIAA0272(gene name synonym)|uniprotkb:hucep-6(orf name)|uniprotkb:BRCA1-associated protein 1(gene name synonym)|uniprotkb:Cerebral protein 6(gene name synonym)	psi-mi:hcfc1_human(display_long)|uniprotkb:HCFC1(gene name)|psi-mi:HCFC1(display_short)|uniprotkb:HCF1(gene name synonym)|uniprotkb:C1 factor(gene name synonym)|uniprotkb:VP16 accessory protein(gene name synonym)|uniprotkb:VCAF(gene name synonym)|uniprotkb:CFF(gene name synonym)|uniprotkb:HFC1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ziad et al. (2013)	pubmed:24211834|imex:IM-21711	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8829641|imex:IM-21711-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-47004N|refseq:NP_004647.1|ensembl:ENSG00000163930(gene)|ensembl:ENST00000460680(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003682"(chromatin binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008233"(peptidase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061519"(macrophage homeostasis)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:1900015"(regulation of cytokine production involved in inflammatory response)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q92560|reactome:R-HSA-5689603|reactome:R-HSA-5693565	refseq:NP_005325.2|refseq:XP_006724879.1|rcsb pdb:6MA1|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|reactome:R-HSA-2151201|reactome:R-HSA-3214847|reactome:R-HSA-5689603|ensembl:ENSG00000172534(gene)|ensembl:ENST00000310441(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0019046"(release from viral latency)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045296"(cadherin binding)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR036116|interpro:IPR037854|interpro:IPR043536|mint:P51610|rcsb pdb:4GO6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:5LWV|dip:DIP-32955N	-	-	-	figure legend:f1b|comment:"To further assess whether the pS592-BAP1 antibody recognizes phosphorylated BAP1, we  performed IPs of BAP1 and HCF-1 from endogenous HeLa SCEs (Fig 1B). Consistent with previous  reports [5, 8], BAP1 only brings down a small fraction of HCF-1, while HCF-1 brings down a  significant fraction of BAP1. In the absence of UV, there is no detectable pS592-signal in the IP inputs,  yet after UV-treatment the pS592-BAP1 signal is induced and both BAP1 and HCF-1 coimmunoprecipitate  pS592-BAP1."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2013/10/25	2014/10/16	rogid:GMWdT1u5HUl29N+YgC/bCKTbxm49606	rogid:RzsCRe9l6md3DI87H4ZgdR9oBMI9606	intact-crc:1810499203A3331A|rigid:KovQxPFbp2E/brl9/j0+7Ru7RB4	false	phosphorylated residue:592-592	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)